Bifidobacterium longum subsp. infantis S76E is an anaerobe, mesophilic, Gram-positive prokaryote that was isolated from intestine of infant.
Gram-positive rod-shaped anaerobe mesophilic 16S sequence
SI-ID 264248
| @ref 20215 |
|
Last LPSN update
2026-02-09 11:18:10 |
| Domain Bacteria |
| Phylum Actinomycetota |
| Class Actinomycetes |
| Order Bifidobacteriales |
| Family Bifidobacteriaceae |
| Genus Bifidobacterium |
| Species Bifidobacterium longum subsp. infantis |
| Full scientific name Bifidobacterium longum subsp. infantis (Reuter 1963) Mattarelli et al. 2008 |
| Synonyms (1) |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 8516 | BIFIDOBACTERIUM MEDIUM (DSMZ Medium 58) | Medium recipe at MediaDive  | Name: BIFIDOBACTERIUM MEDIUM (DSMZ Medium 58) Composition: Glucose 10.0 g/l Casein peptone 10.0 g/l Bacto Soytone 5.0 g/l Meat extract 5.0 g/l Yeast extract 5.0 g/l L-Cysteine HCl x H2O 0.5 g/l NaHCO3 0.4 g/l NaCl 0.08 g/l MnSO4 x H2O 0.05 g/l KH2PO4 0.04 g/l K2HPO4 0.04 g/l MgSO4 x 7 H2O 0.02 g/l CaCl2 x 2 H2O 0.01 g/l Tween 80 Resazurin Distilled water | ||
| 38032 | MEDIUM 20 - for Anaerobic bacteria | Agar (15.000 g);Glucose (5.000 g);Yeast extract (20.000 g);Tryptone (30.000 g);Cysteine hydrochloride (0.500 g);distilled water (1000.000 ml);Hemin solution -M00149 (25.000 ml) | |||
| 116049 | CIP Medium 72 | Medium recipe at CIP | |||
| 116049 | CIP Medium 20 | Medium recipe at CIP |
| @ref | Murein short key | Type | |
|---|---|---|---|
| 8516 | A21.03 | A3ß L-Orn-L-Ser-L-Ala-L-Thr-L-Ala |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68371 | 27613 ChEBI | amygdalin | - | builds acid from | from API 50CH acid |
| 68371 | 18305 ChEBI | arbutin | - | builds acid from | from API 50CH acid |
| 68371 | 17057 ChEBI | cellobiose | - | builds acid from | from API 50CH acid |
| 68371 | 18333 ChEBI | D-arabitol | - | builds acid from | from API 50CH acid |
| 68371 | 28847 ChEBI | D-fucose | - | builds acid from | from API 50CH acid |
| 68371 | 62318 ChEBI | D-lyxose | - | builds acid from | from API 50CH acid |
| 68371 | 16899 ChEBI | D-mannitol | - | builds acid from | from API 50CH acid |
| 68371 | 17924 ChEBI | D-sorbitol | - | builds acid from | from API 50CH acid |
| 68371 | 16443 ChEBI | D-tagatose | - | builds acid from | from API 50CH acid |
| 68371 | 17113 ChEBI | erythritol | - | builds acid from | from API 50CH acid |
| 68371 | 16813 ChEBI | galactitol | - | builds acid from | from API 50CH acid |
| 68371 | 28066 ChEBI | gentiobiose | - | builds acid from | from API 50CH acid |
| 68371 | 24265 ChEBI | gluconate | - | builds acid from | from API 50CH acid |
| 68371 | 17754 ChEBI | glycerol | - | builds acid from | from API 50CH acid |
| 68371 | 28087 ChEBI | glycogen | - | builds acid from | from API 50CH acid |
| 68371 | 15443 ChEBI | inulin | - | builds acid from | from API 50CH acid |
| 68371 | 30849 ChEBI | L-arabinose | - | builds acid from | from API 50CH acid |
| 68371 | 18403 ChEBI | L-arabitol | - | builds acid from | from API 50CH acid |
| 68371 | 62345 ChEBI | L-rhamnose | - | builds acid from | from API 50CH acid |
| 68371 | 17266 ChEBI | L-sorbose | - | builds acid from | from API 50CH acid |
| 68371 | 65328 ChEBI | L-xylose | - | builds acid from | from API 50CH acid |
| 68371 | 320061 ChEBI | methyl alpha-D-glucopyranoside | - | builds acid from | from API 50CH acid |
| 68371 | 43943 ChEBI | methyl alpha-D-mannoside | - | builds acid from | from API 50CH acid |
| 68371 | 74863 ChEBI | methyl beta-D-xylopyranoside | - | builds acid from | from API 50CH acid |
| 68371 | 59640 ChEBI | N-acetylglucosamine | - | builds acid from | from API 50CH acid |
| 116049 | 17632 ChEBI | nitrate | - | reduction | |
| 116049 | 16301 ChEBI | nitrite | - | reduction | |
| 68371 | Potassium 2-ketogluconate | - | builds acid from | from API 50CH acid | |
| 68371 | 15963 ChEBI | ribitol | - | builds acid from | from API 50CH acid |
| 68371 | 17814 ChEBI | salicin | - | builds acid from | from API 50CH acid |
| 68371 | 28017 ChEBI | starch | - | builds acid from | from API 50CH acid |
| 68371 | 27082 ChEBI | trehalose | - | builds acid from | from API 50CH acid |
| 68371 | 32528 ChEBI | turanose | - | builds acid from | from API 50CH acid |
| 68371 | 17151 ChEBI | xylitol | - | builds acid from | from API 50CH acid |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68382 | acid phosphatase | - | 3.1.3.2 | from API zym |
| 68382 | alkaline phosphatase | - | 3.1.3.1 | from API zym |
| 68382 | alpha-chymotrypsin | - | 3.4.21.1 | from API zym |
| 68382 | alpha-fucosidase | - | 3.2.1.51 | from API zym |
| 68382 | alpha-galactosidase | + | 3.2.1.22 | from API zym |
| 68382 | alpha-glucosidase | + | 3.2.1.20 | from API zym |
| 68382 | alpha-mannosidase | - | 3.2.1.24 | from API zym |
| 68382 | beta-galactosidase | + | 3.2.1.23 | from API zym |
| 68382 | beta-glucosidase | + | 3.2.1.21 | from API zym |
| 68382 | beta-glucuronidase | - | 3.2.1.31 | from API zym |
| 116049 | catalase | - | 1.11.1.6 | |
| 68382 | cystine arylamidase | - | 3.4.11.3 | from API zym |
| 68382 | esterase (C 4) | - | from API zym | |
| 68382 | esterase lipase (C 8) | - | from API zym | |
| 68382 | leucine arylamidase | - | 3.4.11.1 | from API zym |
| 68382 | lipase (C 14) | - | from API zym | |
| 68382 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API zym |
| 68382 | naphthol-AS-BI-phosphohydrolase | - | from API zym | |
| 116049 | oxidase | - | ||
| 68382 | trypsin | - | 3.4.21.4 | from API zym |
| 116049 | urease | - | 3.5.1.5 | |
| 68382 | valine arylamidase | - | from API zym |
| @ref | ControlQ | GLY | ERY | DARA | LARA | RIB | DXYL | LXYL | ADO | MDX | GAL | GLU | FRU | MNE | SBE | RHA | DUL | INO | MAN | SOR | MDM | MDG | NAG | AMY | ARB | ESC | SAL | CEL | MAL | LAC | MEL | SAC | TRE | INU | MLZ | RAF | AMD | GLYG | XLT | GEN | TUR | LYX | TAG | DFUC | LFUC | DARL | LARL | GNT | 2KG | 5KG | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 8516 | - | - | - | + | - | - | + | - | - | - | + | + | + | + | - | - | - | + | - | - | - | - | - | - | - | + | - | - | + | + | + | + | - | - | - | + | - | - | - | - | - | - | - | - | + | - | - | - | - | - | |
| 8516 | - | - | - | - | - | + | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | + | + | - | + | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| 116049 | not determinedn.d. | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + |
| @ref | Description | Accession | Length | Database | NCBI tax ID | |
|---|---|---|---|---|---|---|
| 20218 | Bifidobacterium longum subsp. infantis gene for 16S rRNA, partial sequence, strain: JCM 1272 | AB116307 | 475 |   | 1682 | |
| 20218 | Bifidobacterium longum gene for 16S rRNA, partial sequence, strain: JCM 1272 | AB507105 | 664 | | 216816 | |
| 124043 | Bifidobacterium longum subsp. infantis gene for 16S ribosomal RNA, partial sequence, strain: YIT 4019. | AB924514 | 1513 | | 1682 | |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Supplemented Infant Formula and Human Breast Milk Show Similar Patterns in Modulating Infant Microbiota Composition and Function In Vitro. | Borewicz K, Bruck WM. | Int J Mol Sci | 10.3390/ijms25031806 | 2024 | | |
| How Do Prebiotics Affect Human Intestinal Bacteria?-Assessment of Bacterial Growth with Inulin and XOS In Vitro. | Schropp N, Stanislas V, Michels KB, Thriene K. | Int J Mol Sci | 10.3390/ijms241612796 | 2023 | | |
| A Small Molecule-Screening Pipeline to Evaluate the Therapeutic Potential of 2-Aminoimidazole Molecules Against Clostridium difficile. | Thanissery R, Zeng D, Doyle RG, Theriot CM. | Front Microbiol | 10.3389/fmicb.2018.01206 | 2018 | | |
| DNA enrichment and tagmentation method for species-level identification and strain-level differentiation using ON-rep-seq. | Krych L, Castro-Mejia JL, Forero-Junco LM, Moesby DN, Mikkelsen MB, Rasmussen MA, Sykulski M, Nielsen DS. | Commun Biol | 10.1038/s42003-019-0617-x | 2019 | | |
| Trophic Interactions of Infant Bifidobacteria and Eubacterium hallii during L-Fucose and Fucosyllactose Degradation. | Schwab C, Ruscheweyh HJ, Bunesova V, Pham VT, Beerenwinkel N, Lacroix C. | Front Microbiol | 10.3389/fmicb.2017.00095 | 2017 | | |
| Metabolism | Intestinal integrity and Akkermansia muciniphila, a mucin-degrading member of the intestinal microbiota present in infants, adults, and the elderly. | Collado MC, Derrien M, Isolauri E, de Vos WM, Salminen S. | Appl Environ Microbiol | 10.1128/aem.01477-07 | 2007 | |
| Indole Derivatives Biosynthesis in Bifidobacterium longum subsp. infantis and the Tryptophan Substrate Availability. | Zhang SM, Wu HC, Hung JH, Huang SL. | Microb Biotechnol | 10.1111/1751-7915.70167 | 2025 | | |
| A human milk oligosaccharide prevents intestinal inflammation in adulthood via modulating gut microbial metabolism. | Schalich KM, Buendia MA, Kaur H, Choksi YA, Washington MK, Codreanu GS, Sherrod SD, McLean JA, Peek RM, Acra SA, Townsend SD, Yan F. | mBio | 10.1128/mbio.00298-24 | 2024 | | |
| Human milk oligosaccharides combine with Bifidobacterium longum to form the "golden shield" of the infant intestine: metabolic strategies, health effects, and mechanisms of action. | Yang S, Cai J, Su Q, Li Q, Meng X. | Gut Microbes | 10.1080/19490976.2024.2430418 | 2024 | | |
| Metabolism | Galacto- and Fructo-oligosaccharides Utilized for Growth by Cocultures of Bifidobacterial Species Characteristic of the Infant Gut. | Sims IM, Tannock GW. | Appl Environ Microbiol | 10.1128/aem.00214-20 | 2020 | |
| Potential Applications of Endo-beta-N-Acetylglucosaminidases From Bifidobacterium longum Subspecies infantis in Designing Value-Added, Next-Generation Infant Formulas. | Duman H, Kaplan M, Arslan A, Sahutoglu AS, Kayili HM, Frese SA, Karav S. | Front Nutr | 10.3389/fnut.2021.646275 | 2021 | | |
| Evaluation of the microbiota-sparing properties of the anti-staphylococcal antibiotic afabicin. | Nowakowska J, Cameron DR, De Martino A, Kuhn J, Le Fresne-Languille S, Leuillet S, Amouzou Y, Wittke F, Carton T, Le Vacon F, Chaves RL, Nicolas-Metral V, Vuagniaux G. | J Antimicrob Chemother | 10.1093/jac/dkad181 | 2023 | | |
| Metabolism | In Vitro Prebiotic and Anti-Colon Cancer Activities of Agar-Derived Sugars from Red Seaweeds. | Yun EJ, Yu S, Kim YA, Liu JJ, Kang NJ, Jin YS, Kim KH. | Mar Drugs | 10.3390/md19040213 | 2021 | |
| Metabolism | Detection of galectin-3 interaction with commensal bacteria. | Kavanaugh D, Kane M, Joshi L, Hickey RM. | Appl Environ Microbiol | 10.1128/aem.03694-12 | 2013 | |
| Metabolism | Bioaccessible antioxidants in milk fermented by Bifidobacterium longum subsp. longum strains. | Gagnon M, Savard P, Riviere A, LaPointe G, Roy D. | Biomed Res Int | 10.1155/2015/169381 | 2015 | |
| Pathogenicity | Exposure of Bifidobacterium longum subsp. infantis to Milk Oligosaccharides Increases Adhesion to Epithelial Cells and Induces a Substantial Transcriptional Response. | Kavanaugh DW, O'Callaghan J, Butto LF, Slattery H, Lane J, Clyne M, Kane M, Joshi L, Hickey RM. | PLoS One | 10.1371/journal.pone.0067224 | 2013 | |
| Transcription analysis of a lantibiotic gene cluster from Bifidobacterium longum DJO10A. | Lee JH, Li X, O'Sullivan DJ. | Appl Environ Microbiol | 10.1128/aem.00571-11 | 2011 | | |
| Prebiotic and Functional Fibers from Micro- and Macroalgae: Gut Microbiota Modulation, Health Benefits, and Food Applications. | Deniz N, Saritas S, Bechelany M, Karav S. | Int J Mol Sci | 10.3390/ijms262211082 | 2025 | | |
| Metabolism | Comparative transcriptomics reveals key differences in the response to milk oligosaccharides of infant gut-associated bifidobacteria. | Garrido D, Ruiz-Moyano S, Lemay DG, Sela DA, German JB, Mills DA. | Sci Rep | 10.1038/srep13517 | 2015 | |
| Bifidobacterial species differentially affect expression of cell surface markers and cytokines of dendritic cells harvested from cord blood. | Young SL, Simon MA, Baird MA, Tannock GW, Bibiloni R, Spencely K, Lane JM, Fitzharris P, Crane J, Town I, Addo-Yobo E, Murray CS, Woodcock A. | Clin Diagn Lab Immunol | 10.1128/cdli.11.4.686-690.2004 | 2004 | | |
| Enzymology | Identification, detection, and enumeration of human bifidobacterium species by PCR targeting the transaldolase gene. | Requena T, Burton J, Matsuki T, Munro K, Simon MA, Tanaka R, Watanabe K, Tannock GW. | Appl Environ Microbiol | 10.1128/aem.68.5.2420-2427.2002 | 2002 | |
| Phylogeny | Comparison of the compositions of the stool microbiotas of infants fed goat milk formula, cow milk-based formula, or breast milk. | Tannock GW, Lawley B, Munro K, Gowri Pathmanathan S, Zhou SJ, Makrides M, Gibson RA, Sullivan T, Prosser CG, Lowry D, Hodgkinson AJ. | Appl Environ Microbiol | 10.1128/aem.03910-12 | 2013 | |
| Enzymology | Detection of Bifidobacterium animalis subsp. lactis (Bb12) in the intestine after feeding of sows and their piglets. | Solano-Aguilar G, Dawson H, Restrepo M, Andrews K, Vinyard B, Urban JF. | Appl Environ Microbiol | 10.1128/aem.00309-08 | 2008 | |
| Phylogeny | Identification and tracing of Bifidobacterium species by use of enterobacterial repetitive intergenic consensus sequences. | Ventura M, Meylan V, Zink R. | Appl Environ Microbiol | 10.1128/aem.69.7.4296-4301.2003 | 2003 | |
| Pathogenicity | Novel riboswitch-binding flavin analog that protects mice against Clostridium difficile infection without inhibiting cecal flora. | Blount KF, Megyola C, Plummer M, Osterman D, O'Connell T, Aristoff P, Quinn C, Chrusciel RA, Poel TJ, Schostarez HJ, Stewart CA, Walker DP, Wuts PG, Breaker RR. | Antimicrob Agents Chemother | 10.1128/aac.01282-15 | 2015 | |
| Enzymology | Species-specific oligonucleotide probes for five Bifidobacterium species detected in human intestinal microflora. | Yamamoto T, Morotomi M, Tanaka R. | Appl Environ Microbiol | 10.1128/aem.58.12.4076-4079.1992 | 1992 | |
| Enzymology | Distribution of bifidobacterial species in human intestinal microflora examined with 16S rRNA-gene-targeted species-specific primers. | Matsuki T, Watanabe K, Tanaka R, Fukuda M, Oyaizu H. | Appl Environ Microbiol | 10.1128/aem.65.10.4506-4512.1999 | 1999 | |
| Phylogeny | Quantification of different Eubacterium spp. in human fecal samples with species-specific 16S rRNA-targeted oligonucleotide probes. | Schwiertz A, Le Blay G, Blaut M. | Appl Environ Microbiol | 10.1128/aem.66.1.375-382.2000 | 2000 | |
| In vitro competition with Bifidobacterium strains impairs potentially pathogenic growth of Clostridium perfringens on 2'-fucosyllactose. | Nakajima A, Arzamasov AA, Sakanaka M, Murakami R, Kozakai T, Yoshida K, Katoh T, Ojima MN, Hirose J, Nagao S, Xiao JZ, Odamaki T, Rodionov DA, Katayama T. | Gut Microbes | 10.1080/19490976.2025.2478306 | 2025 | | |
| Biotechnology | A Human Gut Commensal Ferments Cranberry Carbohydrates To Produce Formate. | Ozcan E, Sun J, Rowley DC, Sela DA. | Appl Environ Microbiol | 10.1128/aem.01097-17 | 2017 | |
| Metabolism | Broad conservation of milk utilization genes in Bifidobacterium longum subsp. infantis as revealed by comparative genomic hybridization. | LoCascio RG, Desai P, Sela DA, Weimer B, Mills DA. | Appl Environ Microbiol | 10.1128/aem.00675-10 | 2010 | |
| Phylogeny | Imbalances in faecal and duodenal Bifidobacterium species composition in active and non-active coeliac disease. | Collado MC, Donat E, Ribes-Koninckx C, Calabuig M, Sanz Y. | BMC Microbiol | 10.1186/1471-2180-8-232 | 2008 | |
| Application of probiotic bacteria in ginsenoside bioconversion and enhancing its health-promoting benefits: a review. | Vasquez R, Song JH, Park YS, Paik HD, Kang DK. | Food Sci Biotechnol | 10.1007/s10068-024-01734-6 | 2025 | | |
| 2'-Fucosyllactose as a prebiotic modulates the probiotic responses of Bifidobacterium bifidum. | Du J, Yang H. | Curr Res Food Sci | 10.1016/j.crfs.2025.100975 | 2025 | | |
| Microbial interactions and the homeostasis of the gut microbiome: the role of Bifidobacterium. | Martin AJM, Serebrinsky-Duek K, Riquelme E, Saa PA, Garrido D. | Microbiome Res Rep | 10.20517/mrr.2023.10 | 2023 | | |
| Feasibility of Using Seaweed (Gracilaria coronopifolia) Synbiotic as a Bioactive Material for Intestinal Health. | Li PH, Lu WC, Chan YJ, Zhao YP, Nie XB, Jiang CX, Ji YX. | Foods | 10.3390/foods8120623 | 2019 | | |
| Designing primers and evaluation of the efficiency of propidium monoazide - Quantitative polymerase chain reaction for counting the viable cells of Lactobacillus gasseri and Lactobacillus salivarius. | Lai CH, Wu SR, Pang JC, Ramireddy L, Chiang YC, Lin CK, Tsen HY. | J Food Drug Anal | 10.1016/j.jfda.2016.10.004 | 2017 | | |
| Genetics | Genomic insights into bifidobacteria. | Lee JH, O'Sullivan DJ. | Microbiol Mol Biol Rev | 10.1128/mmbr.00004-10 | 2010 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive1744.20251217.10
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
License