Name: Bifidobacterium longum E194b (Variant a)
Creator: BacDive
License: https://creativecommons.org/licenses/by/4.0/

Strain identifier

BacDive ID: 1709

Type strain:

Species: Bifidobacterium longum

Strain Designation: E194b (Variant a), E194b

Culture col. no.: DSM 20219, ATCC 15707, NCTC 11818, CCUG 28903, LMG 13197, JCM 1217, LMG 10497, BCRC 11847, CECT 4503, CIP 64.62, KCTC 3128, KCTC 3215, NCFB 2259, VTT E-96664, NCDO 2259, WDCM 00225

Strain history: CIP <- 1964, Lab. Ident. Inst. Pasteur, Paris, France <- M. Sebald, Inst. Pasteur, Paris, France <- H. Werner <- G. Reuter: strain E194b

NCBI tax ID(s): 565042 (strain), 216816 (species)

SI-ID 376921

CECT 4503, ATCC 15707, CCRC 11847, CCUG 28903, CECT 4554, CIP 64.62, JCM 1217, LMG 10497, NCFB 2259, NCTC 11818, AS 1.2186, BCRC 11847, DSM 20219, HAMBI 554, KCTC 3128, LMG 13197, NCAIM B.01819, NCIMB 702259, VTT E-96664, NCDO 2259

Special Collections

Other strains from Bifidobacterium longum

Section

Bifidobacterium longum E194b is an anaerobe, Gram-positive bacterium that was isolated from intestine of adult.

Gram-positive
anaerobe
16S sequence
Bacteria
genome sequence

Information on the name and the taxonomic classification. Name and taxonomic classification

	Last LPSN update	14-12-2023 (DD-MM-YYYY)
	Domain	"Bacteria"
	Phylum	*Actinomycetota*
	Class	*Actinomycetes*
	Order	*Bifidobacteriales*
	Family	*Bifidobacteriaceae*
	Genus	*Bifidobacterium*
	Species	**Bifidobacterium longum**
	Full Scientific Name (LPSN)	Bifidobacterium longum Reuter 1963 (Approved Lists 1980)

Information on morphological and physiological properties Morphology

[Ref.: #120652]	Gram stain	positive

[Ref.: #120652]	Cell shape	rod-shaped

[Ref.: #120652]	Motility	no
[Ref.: #69480]	Motility	no Confidence in %93

Information on culture and growth conditions Culture and growth conditions

[Ref.: #38030]

Culture medium

MEDIUM 20 - for Anaerobic bacteria

[Ref.: #38030]

Culture medium growth

[Ref.: #38030]

Culture medium composition

expand / minimize

[Ref.: #8612]

Culture medium

BIFIDOBACTERIUM MEDIUM (DSMZ Medium 58)

[Ref.: #8612]

Culture medium growth

[Ref.: #8612]

Culture medium link

Medium recipe at MediaDive

[Ref.: #8612]

Culture medium composition

expand / minimize

[Ref.: #120652]

Culture medium

CIP Medium 20

[Ref.: #120652]

Culture medium growth

[Ref.: #120652]

Culture medium link

Medium recipe provided by DSMZ

		Temperature
[Ref.: #8612]	growth	37 °C
[Ref.: #38030]	growth	37 °C
[Ref.: #49449]	growth	37 °C
[Ref.: #67770]	growth	37 °C

Information on physiology and metabolism Physiology and metabolism

[Ref.: #8612]	Oxygen tolerance	anaerobe
[Ref.: #49449]	Oxygen tolerance	anaerobe
[Ref.: #120652]	Oxygen tolerance	facultative anaerobe

[Ref.: #8612]	Murein short key	A21.03
[Ref.: #8612]	Murein types	A3ß L-Orn-L-Ser-L-Ala-L-Thr-L-Ala

	Metabolite	Utilization activity	Kind of utilization tested
[Ref.: #68371]	amygdalin ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	arbutin ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	cellobiose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-arabinose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-arabitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-fructose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-fucose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-galactose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-glucose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-lyxose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-mannitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-ribose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-sorbitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-tagatose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-xylose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	erythritol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	galactitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	gentiobiose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	gluconate ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	glycerol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	glycogen ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-arabinose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-arabitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-fucose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-rhamnose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-xylose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	lactose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	maltose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	melezitose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	melibiose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	methyl alpha-D-glucopyranoside ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	methyl beta-D-xylopyranoside ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	myo-inositol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	N-acetylglucosamine ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #120652]	nitrate ChEBI	-	reduction
[Ref.: #120652]	nitrite ChEBI	-	reduction
[Ref.: #68371]	Potassium 2-ketogluconate ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	raffinose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	ribitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	salicin ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	xylitol ChEBI	-	builds acid from	* from API 50CH acid
	Only first 10 entries are displayed. Click here to see all.

	Metabolite production	Metabolite	Production
[Ref.: #120652]		indole ChEBI	no

	Enzyme	Enzyme activity	EC number
[Ref.: #68382]	acid phosphatase	+	3.1.3.2	* from API zym
[Ref.: #68382]	alkaline phosphatase	-	3.1.3.1	* from API zym
[Ref.: #68382]	alpha-chymotrypsin	-	3.4.21.1	* from API zym
[Ref.: #68382]	alpha-fucosidase	-	3.2.1.51	* from API zym
[Ref.: #68382]	alpha-galactosidase	+	3.2.1.22	* from API zym
[Ref.: #68382]	alpha-glucosidase	+	3.2.1.20	* from API zym
[Ref.: #68382]	alpha-mannosidase	-	3.2.1.24	* from API zym
[Ref.: #68382]	beta-galactosidase	+	3.2.1.23	* from API zym
[Ref.: #68382]	beta-glucosidase	+	3.2.1.21	* from API zym
[Ref.: #68382]	beta-glucuronidase	-	3.2.1.31	* from API zym
[Ref.: #120652]	catalase	-	1.11.1.6
[Ref.: #68382]	cystine arylamidase	-	3.4.11.3	* from API zym
[Ref.: #68382]	esterase (C 4)	+		* from API zym
[Ref.: #68382]	esterase lipase (C 8)	+		* from API zym
[Ref.: #68382]	leucine arylamidase	+	3.4.11.1	* from API zym
[Ref.: #68382]	lipase (C 14)	-		* from API zym
[Ref.: #68382]	N-acetyl-beta-glucosaminidase	+	3.2.1.52	* from API zym
[Ref.: #68382]	naphthol-AS-BI-phosphohydrolase	-		* from API zym
[Ref.: #120652]	oxidase	-
[Ref.: #68382]	trypsin	-	3.4.21.4	* from API zym
[Ref.: #120652]	urease	-	3.5.1.5
[Ref.: #68382]	valine arylamidase	-		* from API zym
	Only first 10 entries are displayed. Click here to see all.

API® 50CH acid:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	ControlQ	Acid from glycerolGLY	Acid from erythritolERY	Acid from D-arabinoseDARA	Acid from L-arabinoseLARA	Acid from D-riboseRIB	Acid from D-xyloseDXYL	Acid from L-xyloseLXYL	Acid from D-adonitolADO	Acid from methyl beta-D-xylopyranosideMDX	Acid from D-galactoseGAL	Acid from D-glucoseGLU	Acid from D-fructoseFRU	Acid from D-mannoseMNE	Acid from L-sorboseSBE	Acid from L-rhamnoseRHA	Acid from dulcitolDUL	Acid from inositolINO	Acid from D-mannitolMAN	Acid from D-sorbitolSOR	Acid from methyl alpha-D-mannopyranosideMDM	Acid from methyl alpha-D-glucopyranosideMDG	Acid from N-acetyl-glucosamineNAG	Acid from amygdalinAMY	Acid from arbutinARB	Acid from esculinESC	Acid from salicinSAL	Acid from cellobioseCEL	Acid from maltoseMAL	Acid from lactoseLAC	Acid from melibioseMEL	Acid from sucroseSAC	Acid from trehaloseTRE	Acid from inulinINU	Acid from melezitoseMLZ	Acid from raffinoseRAF	Acid from starchAMD	Acid from glycogenGLYG	Acid from xylitolXLT	Acid from gentiobioseGEN	Acid from turanoseTUR	Acid from D-lyxoseLYX	Acid from D-tagatoseTAG	Acid from D-fucoseDFUC	Acid from L-fucoseLFUC	Acid from D-arabitolDARL	Acid from L-arabitolLARL	Acid from gluconateGNT	Acid from 2-Ketogluconate2KG	Acid from 5-Ketogluconate5KG
[Ref.: #8612]	14585	-	-	-	-	+	+	+	-	-	-	+	+	+	-	-	-	-	-	-	-	-	+	-	-	-	+	-	-	+	+	+	+	-	-	+	+	-	-	-	-	+	-	-	-	-	-	-	-	-	-
[Ref.: #8612]	14584	-	-	-	-	+	+	+	-	-	-	+	+	+	+	+	-	-	-	-	-	+/-	+	-	-	-	-	-	-	+	+	+	+	+	+	+	+	+/-	-	-	-	+/-	-	-	-	-	-	-	-	-	+/-
[Ref.: #8612]	14583	-	-	-	-	+	+	+	-	-	-	+	+	+	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	+	+	+	+	-	-	+	+	-	-	-	-	+/-	-	-	-	-	-	-	-	-	-
[Ref.: #8612]	14582	-	-	-	-	+	+	+	-	-	-	+	+	+	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	+	+	+	-	-	-	+	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-

API® zym:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	Control	2-naphthyl phosphateAlkaline phosphatase	2-naphthyl butyrateEsterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	2-naphthyl myristateLipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	N-benzoyl-DL-arginine-2-naphthylamideTrypsin	N-glutaryl-phenylalanine-2-naphthylamidealpha- Chymotrypsin	2-naphthyl phosphateAcid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	6-Br-2-naphthyl-alphaD-galactpyranosidealpha- Galactosidase	2-naphthyl-betaD-galactpyranosidebeta- Galactosidase	Naphthol-AS-BI-betaD-glucuronidebeta- Glucuronidase	2-naphthyl-alphaD-glucopyranosidealpha- Glucosidase	6-Br-2-naphthyl-betaD-glucopyranosidebeta- Glucosidase	1-naphthyl-N-acetyl-betaD-glucosaminideN-acetyl-beta- glucosaminidase	6-Br-2-naphthyl-alphaD-mannopyranosidealpha- Mannosidase	2-naphthyl-alphaL-fucopyranosidealpha- Fucosidase
[Ref.: #120652]	13061	-	-	+	+	-	+	-	-	-	-	+	-	+	+	-	+	+	+	-	-

Information on isolation source, the sampling and environmental conditions Isolation, sampling and environmental information

[Ref.: #8612]	Sample type/isolated from	intestine of adult

[Ref.: #49449]	Sample type/isolated from	Human intestine,adult

[Ref.: #67770]	Sample type/isolated from	Intestine of adult

[Ref.: #120652]	Sample type/isolated from	Human, Intestine (adult)
* marker position based on {}

Isolation sources categories

#Host Body-Site

#Gastrointestinal tract

What are isolation sources categories?

[Ref.: #69479]

Global distribution of 16S sequence LC071818 (>99% sequence identity) for Bifidobacterium longum subclade from Microbeatlas

Aquatic Samples	7450
Soil Samples	1795
Animal Samples	197025
Plant Samples	785
Total Samples	207055

Information on possible application of the strain and its possible interaction with e.g. potential hosts Safety information

[Ref.: #8612]	Biosafety level	1	Risk group (German classification) According to TRBA 466
[Ref.: #120652]	Biosafety level	1	Risk group (French classification)

Information on genomic background e.g. entries in nucleic sequence databass Sequence information

16S Sequence information:

Only first 5 entries are displayed. Click here to see all.

	Sequence accession description	Seq. accession number	Sequence length (bp)	Sequence database	Associated NCBI tax ID
[Ref.: #67770]	Bifidobacterium longum subsp. longum gene for 16S ribosomal RNA, partial sequence, strain: JCM 1217	LC071818	1456	GenBank ENA	1679 tax ID
[Ref.: #67770]	Bifidobacterium longum subsp. longum gene for 16S ribosomal RNA, partial sequence	AB437359	1507	GenBank ENA	1679 tax ID
[Ref.: #20218]	Bifidobacterium longum subsp. longum strain DSM 20219 16S ribosomal RNA gene, partial sequence	HQ012022	940	GenBank ENA	1679 tax ID	*
[Ref.: #20218]	Bifidobacterium longum subsp. longum JCM 1217 gene for 16S rRNA, partial sequence	AB116313	476	GenBank ENA	565042 tax ID	*
[Ref.: #20218]	Bifidobacterium longum gene for 16S rRNA, partial sequence, strain: JCM 1217	AB507101	669	GenBank ENA	565042 tax ID	*
[Ref.: #20218]	Bifidobacterium longum subsp. longum strain KCTC 3128 16S ribosomal RNA gene, partial sequence	GU361823	1477	GenBank ENA	1679 tax ID	*
[Ref.: #20218]	Bifidobacterium longum strain ATCC 15707 16S ribosomal RNA gene, partial sequence	M58739	1476	GenBank ENA	216816 tax ID	*
[Ref.: #20218]	Bifidobacterium longum (ATCC 15707) 16S ribosomal RNA gene, partial	M84781	642	GenBank ENA	216816 tax ID	*

Genome sequence information:

Only first 5 entries are displayed. Click here to see all.

	Sequence accession description	Seq. accession number	Assembly level	Sequence database	Associated NCBI tax ID
[Ref.: #67770]	Bifidobacterium longum DSM 20219	GCA_900104835	contig	GenBank ENA	216816 tax ID
[Ref.: #67770]	Bifidobacterium longum subsp. longum LMG 13197	GCA_000741245	contig	GenBank ENA	1679 tax ID
[Ref.: #66792]	Bifidobacterium longum subsp. longum JCM 1217	GCA_000196555	complete	GenBank ENA	565042 tax ID	*
[Ref.: #66792]	Bifidobacterium longum strain DSM 20219	216816.128	wgs	PATRIC	216816 tax ID	*
[Ref.: #66792]	Bifidobacterium longum strain NCTC11818	216816.359	complete	PATRIC	216816 tax ID	*
[Ref.: #66792]	Bifidobacterium longum subsp. longum JCM 1217	565042.3	complete	PATRIC	565042 tax ID	*

[Ref.: #8612]	GC-content	61.4 mol%
[Ref.: #67770]	GC-content	61.4 mol%	thermal denaturation, midpoint method (Tm)
[Ref.: #67770]	GC-content	61.3 mol%	high performance liquid chromatography (HPLC)

Data predicted using genome information as a basis Genome-based predictions

	Trait	Model	Prediction	Confidence in %	In training data
	Predictions from Diaspora project based on: Bifidobacterium longum subsp. longum JCM 1217 JCM 1217 NCBI: GCA_000196555.1
[Ref.: #69480]	gram-positive	gram-positiveⓘ	yes	87.752	no
[Ref.: #69480]	anaerobic	anaerobicⓘ	yes	83.288	no
[Ref.: #69480]	aerobic	aerobicⓘ	no	91.961	yes
[Ref.: #69480]	spore-forming	spore-formingⓘ	no	88.307	no
[Ref.: #69480]	thermophilic	thermophileⓘ	no	92.967	yes
[Ref.: #69480]	flagellated	motile2+ⓘ	no	93	no

Availability in culture collections External links

[Ref.: #8612]

Culture collection no.

DSM 20219, ATCC 15707, NCTC 11818, CCUG 28903, LMG 13197, JCM 1217, LMG 10497, BCRC 11847, CECT 4503, CIP 64.62, KCTC 3128, KCTC 3215, NCFB 2259, VTT E-96664, NCDO 2259, WDCM 00225

[Ref.: #71356]

SI-ID 376921

Literature:

Only first 10 entries are displayed. Click here to see all.

Topic	Title	Authors	Journal	DOI	Year
Metabolism	Two alpha-L-arabinofuranosidases from Bifidobacterium longum subsp. longum are involved in arabinoxylan utilization.	Komeno M, Yoshihara Y, Kawasaki J, Nabeshima W, Maeda K, Sasaki Y, Fujita K, Ashida H	Appl Microbiol Biotechnol	10.1007/s00253-022-11845-x	2022	*
Pathogenicity	Crystal structures of glycoside hydrolase family 136 lacto-N-biosidases from monkey gut- and human adult gut bacteria.	Yamada C, Katayama T, Fushinobu S	Biosci Biotechnol Biochem	10.1093/bbb/zbac015	2022	*
Metabolism	Novel 3-O-alpha-d-Galactosyl-alpha-l-Arabinofuranosidase for the Assimilation of Gum Arabic Arabinogalactan Protein in Bifidobacterium longum subsp. longum.	Sasaki Y, Horigome A, Odamaki T, Xiao JZ, Ishiwata A, Ito Y, Kitahara K, Fujita K	Appl Environ Microbiol	10.1128/AEM.02690-20	2021	*
Enzymology	Crystal structure of beta-L-arabinobiosidase belonging to glycoside hydrolase family 121.	Saito K, Viborg AH, Sakamoto S, Arakawa T, Yamada C, Fujita K, Fushinobu S	PLoS One	10.1371/journal.pone.0231513	2020	*
Pathogenicity	Rheological properties of a neutral polysaccharide extracted from maca (Lepidium meyenii Walp.) roots with prebiotic and anti-inflammatory activities.	Lee YK, Jung SK, Chang YH	Int J Biol Macromol	10.1016/j.ijbiomac.2020.02.307	2020	*
Biotechnology	Viability assessment of Bifidobacterium longum ATCC 15707 on non-dairy foods using quantitative fluorescence microscopy.	Min M, Mason SL, Bennett GN, Hussain MA, Bunt CR	J Microbiol Methods	10.1016/j.mimet.2019.105778	2019	*
Metabolism	Efficient Phytase Secretion and Phytate Degradation by Recombinant Bifidobacterium longum JCM 1217.	Sun Z, Yue Z, Yang X, Hao X, Song M, Li L, Chen C, Chu C, Li C	Front Microbiol	10.3389/fmicb.2019.00796	2019	*
Metabolism	Two Novel alpha-l-Arabinofuranosidases from Bifidobacterium longum subsp. longum Belonging to Glycoside Hydrolase Family 43 Cooperatively Degrade Arabinan.	Komeno M, Hayamizu H, Fujita K, Ashida H	Appl Environ Microbiol	10.1128/AEM.02582-18	2019	*
Metabolism	Degradative enzymes for type II arabinogalactan side chains in Bifidobacterium longum subsp. longum.	Fujita K, Sakamoto A, Kaneko S, Kotake T, Tsumuraya Y, Kitahara K	Appl Microbiol Biotechnol	10.1007/s00253-018-9566-4	2018	*
Metabolism	How accurate is automated gap filling of metabolic models?	Karp PD, Weaver D, Latendresse M	BMC Syst Biol	10.1186/s12918-018-0593-7	2018	*
Enzymology	Expression and Characterization of Recombinant Sucrose Phosphorylase.	Zhang H, Sun X, Li W, Li T, Li S, Kitaoka M	Protein J	10.1007/s10930-017-9754-6	2018	*
Enzymology	Characterization of novel thermophilic alpha-glucosidase from Bifidobacterium longum.	Kim NR, Jeong DW, Ko DS, Shim JH	Int J Biol Macromol	10.1016/j.ijbiomac.2017.03.009	2017	*
Pathogenicity	Membrane filter method to study the effects of Lactobacillus acidophilus and Bifidobacterium longum on fecal microbiota.	Shimizu H, Benno Y	Microbiol Immunol	10.1111/1348-0421.12332	2015	*
Stress	Cocktails of probiotics pre-adapted to multiple stress factors are more robust under simulated gastrointestinal conditions than their parental counterparts and exhibit enhanced antagonistic capabilities against Escherichia coli and Staphylococcus aureus.	Mathipa MG, Thantsha MS	Gut Pathog	10.1186/s13099-015-0053-5	2015	*
Enzymology	Bifidobacterium longum subsp. longum Exo-beta-1,3-Galactanase, an enzyme for the degradation of type II arabinogalactan.	Fujita K, Sakaguchi T, Sakamoto A, Shimokawa M, Kitahara K	Appl Environ Microbiol	10.1128/AEM.00802-14	2014	*
Enzymology	Crystallization and preliminary X-ray diffraction analysis of a novel beta-L-arabinofuranosidase (HypBA1) from Bifidobacterium longum.	Zhu Z, He M, Huang CH, Ko TP, Zeng YF, Huang YN, Jia S, Lu F, Liu JR, Guo RT	Acta Crystallogr F Struct Biol Commun	10.1107/S2053230X14001812	2014	*
Metabolism	Insights into the binding specificity and catalytic mechanism of N-acetylhexosamine 1-phosphate kinases through multiple reaction complexes.	Wang KC, Lyu SY, Liu YC, Chang CY, Wu CJ, Li TL	Acta Crystallogr D Biol Crystallogr	10.1107/S1399004714004209	2014	*
Metabolism	Characterization of a novel beta-L-arabinofuranosidase in Bifidobacterium longum: functional elucidation of a DUF1680 protein family member.	Fujita K, Takashi Y, Obuchi E, Kitahara K, Suganuma T	J Biol Chem	10.1074/jbc.M113.528711	2014	*
Metabolism	Synergistic antibacterial efficacies of the combination of bovine lactoferrin or its hydrolysate with probiotic secretion in curbing the growth of meticillin-resistant Staphylococcus aureus.	Chen PW, Jheng TT, Shyu CL, Mao FC	J Med Microbiol	10.1099/jmm.0.052639-0	2013	*
Metabolism	Lacto-N-biosidase encoded by a novel gene of Bifidobacterium longum subspecies longum shows unique substrate specificity and requires a designated chaperone for its active expression.	Sakurama H, Kiyohara M, Wada J, Honda Y, Yamaguchi M, Fukiya S, Yokota A, Ashida H, Kumagai H, Kitaoka M, Yamamoto K, Katayama T	J Biol Chem	10.1074/jbc.M113.484733	2013	*
Metabolism	Antimicrobial potential for the combination of bovine lactoferrin or its hydrolysate with lactoferrin-resistant probiotics against foodborne pathogens.	Chen PW, Jheng TT, Shyu CL, Mao FC	J Dairy Sci	10.3168/jds.2012-6112	2013	*
Pathogenicity	Bifidobacterium spp. influences the production of autoinducer-2 and biofilm formation by Escherichia coli O157:H7.	Kim Y, Lee JW, Kang SG, Oh S, Griffiths MW	Anaerobe	10.1016/j.anaerobe.2012.08.006	2012	*
Enzymology	Characterization of a novel beta-L-Arabinofuranosidase in Bifidobacterium longum: functional elucidation of A DUF1680 family member.	Fujita K, Takashi Y, Obuchi E, Kitahara K, Suganuma T	J Biol Chem	10.1074/jbc.M111.248690	2011	*
Metabolism	Physiology of consumption of human milk oligosaccharides by infant gut-associated bifidobacteria.	Asakuma S, Hatakeyama E, Urashima T, Yoshida E, Katayama T, Yamamoto K, Kumagai H, Ashida H, Hirose J, Kitaoka M	J Biol Chem	10.1074/jbc.M111.248138	2011	*
Enzymology	Molecular cloning and characterization of a beta-L-Arabinobiosidase in Bifidobacterium longum that belongs to a novel glycoside hydrolase family.	Fujita K, Sakamoto S, Ono Y, Wakao M, Suda Y, Kitahara K, Suganuma T	J Biol Chem	10.1074/jbc.M110.190512	2010	*
Pathogenicity	Pivotal Advance: Bifidobacteria and Gram-negative bacteria differentially influence immune responses in the proinflammatory milieu of celiac disease.	De Palma G, Cinova J, Stepankova R, Tuckova L, Sanz Y	J Leukoc Biol	10.1189/jlb.0709471	2009	*
Metabolism	Development of silk fibroin-based beads for immobilized cell fermentations.	Yildirim S, Borer ME, Wenk E, Meinel L, Lacroix C	J Microencapsul	10.3109/02652040802217516	2010	*
Pathogenicity	The screening method of a bifidogenic dietary fiber extracted from inedible parts of vegetables.	Iwata E, Hotta H, Goto M	J Nutr Sci Vitaminol (Tokyo)	10.3177/jnsv.55.385	2009	*
Metabolism	In vitro fermentation of arabinoxylan-derived carbohydrates by bifidobacteria and mixed fecal microbiota.	Pastell H, Westermann P, Meyer AS, Tuomainen P, Tenkanen M	J Agric Food Chem	10.1021/jf901397b	2009	*
Metabolism	Crystallographic and mutational analyses of substrate recognition of endo-alpha-N-acetylgalactosaminidase from Bifidobacterium longum.	Suzuki R, Katayama T, Kitaoka M, Kumagai H, Wakagi T, Shoun H, Ashida H, Yamamoto K, Fushinobu S	J Biochem	10.1093/jb/mvp086	2009	*
Pathogenicity	Analysis of tetracycline resistance tet(W) genes and their flanking sequences in intestinal Bifidobacterium species.	Ammor MS, Florez AB, Alvarez-Martin P, Margolles A, Mayo B	J Antimicrob Chemother	10.1093/jac/dkn280	2008	*
Pathogenicity	Differential transcriptional response of Bifidobacterium longum to human milk, formula milk, and galactooligosaccharide.	Gonzalez R, Klaassens ES, Malinen E, de Vos WM, Vaughan EE	Appl Environ Microbiol	10.1128/AEM.00122-08	2008	*
Phylogeny	Proposal to reclassify the three biotypes of Bifidobacterium longum as three subspecies: Bifidobacterium longum subsp. longum subsp. nov., Bifidobacterium longum subsp. infantis comb. nov. and Bifidobacterium longum subsp. suis comb. nov.	Mattarelli P, Bonaparte C, Pot B, Biavati B	Int J Syst Evol Microbiol	10.1099/ijs.0.65319-0	2008	*
Enzymology	Identification of galacto-N-biose phosphorylase from Clostridium perfringens ATCC13124.	Nakajima M, Nihira T, Nishimoto M, Kitaoka M	Appl Microbiol Biotechnol	10.1007/s00253-007-1319-8	2008	*
Enzymology	Purification, crystallization and preliminary X-ray analysis of the galacto-N-biose-/lacto-N-biose I-binding protein (GL-BP) of the ABC transporter from Bifidobacterium longum JCM1217.	Wada J, Suzuki R, Fushinobu S, Kitaoka M, Wakagi T, Shoun H, Ashida H, Kumagai H, Katayama T, Yamamoto K	Acta Crystallogr Sect F Struct Biol Cryst Commun	10.1107/S1744309107036263	2007	*
Metabolism	Identification of N-acetylhexosamine 1-kinase in the complete lacto-N-biose I/galacto-N-biose metabolic pathway in Bifidobacterium longum.	Nishimoto M, Kitaoka M	Appl Environ Microbiol	10.1128/AEM.01425-07	2007	*
Enzymology	Identification and molecular cloning of a novel glycoside hydrolase family of core 1 type O-glycan-specific endo-alpha-N-acetylgalactosaminidase from Bifidobacterium longum.	Fujita K, Oura F, Nagamine N, Katayama T, Hiratake J, Sakata K, Kumagai H, Yamamoto K	J Biol Chem	10.1074/jbc.M506874200	2005	*
Metabolism	Novel putative galactose operon involving lacto-N-biose phosphorylase in Bifidobacterium longum.	Kitaoka M, Tian J, Nishimoto M	Appl Environ Microbiol	10.1128/AEM.71.6.3158-3162.2005	2005	*
Metabolism	Optimization of a Bifidobacterium longum production process.	Kiviharju K, Leisola M, Eerikainen T	J Biotechnol	10.1016/j.jbiotec.2005.02.007	2005	*
Metabolism	Kinetics of Bifidobacterium longum ATCC 15707 fermentations: effect of the dilution rate and carbon source.	Shene C, Mardones M, Zamora P, Bravo S	Appl Microbiol Biotechnol	10.1007/s00253-004-1792-2	2005	*
Metabolism	Fermentation of a milk-soymilk and Lycium chinense Miller mixture using a new isolate of Lactobacillus paracasei subsp. paracasei NTU101 and Bifidobacterium longum.	Lin FM, Chiu CH, Pan TM	J Ind Microbiol Biotechnol	10.1007/s10295-004-0184-z	2004	*
Pathogenicity	Increased stress tolerance of Bifidobacterium longum and Lactococcus lactis produced during continuous mixed-strain immobilized-cell fermentation.	Doleyres Y, Fliss I, Lacroix C	J Appl Microbiol	10.1111/j.1365-2672.2004.02326.x	2004	*
Metabolism	Continuous production of mixed lactic starters containing probiotics using immobilized cell technology.	Doleyres Y, Fliss I, Lacroix C	Biotechnol Prog	10.1021/bp020096w	2004	*
Metabolism	Bifidobacterium longum ATCC 15707 cell production during free- and immobilized-cell cultures in MRS-whey permeate medium.	Doleyres Y, Paquin C, LeRoy M, Lacroix C	Appl Microbiol Biotechnol	10.1007/s00253-002-1103-8	2002	*
Enzymology	Cloning and expression in Escherichia coli of a gene, hup, encoding the histone-like protein HU of Bifidobacterium longum.	Takeuchi A, Matsumura H, Kano Y	Biosci Biotechnol Biochem	10.1271/bbb.66.598	2002	*
Metabolism	Formulations and processing of yogurt affect the microbial quality of carbonated yogurt.	Karagul-Yuceer Y, Wilson JC, White CH	J Dairy Sci	10.3168/jds.S0022-0302(01)74506-7	2001	*
Cultivation	Survival of Bifidobacterium longum immobilized in calcium alginate beads in simulated gastric juices and bile salt solution.	Lee KY, Heo TR	Appl Environ Microbiol	10.1128/AEM.66.2.869-873.2000	2000	*
Metabolism	Investigations of bifidobacterial ecology and oligosaccharide metabolism in a three-stage compound continuous culture system.	McBain AJ, Macfarlane GT	Scand J Gastroenterol Suppl	10.1080/00365521.1997.11720715	1997	*
Enzymology	Viability and enzymatic activity of bifidobacteria in milk.	Hughes DB, Hoover DG	J Dairy Sci	10.3168/jds.S0022-0302(95)76634-6	1995	*
Genetics	Selection of species-specific DNA probes which detect strain restriction polymorphism in four Bifidobacterium species.	Mangin I, Bourget N, Simonet JM, Decaris B	Res Microbiol	10.1016/0923-2508(96)80271-3	1995	*
Cultivation	Effect of chelatants on gellan gel rheological properties and setting temperature for immobilization of living bifidobacteria.	Camelin I, Lacroix C, Paquin C, Prevost H, Cachon R, Divies C	Biotechnol Prog	10.1021/bp00021a008	1993	*
Pathogenicity	Quantitative fluorometric assay for rapid enzymatic characterization of Bifidobacterium longum and related bifidobacteria.	O'Brien M, Mitsuoka T	Microbiol Immunol	10.1111/j.1348-0421.1991.tb01626.x	1991	*
	Effect of Rosemary (Rosmarinus officinalis L.) Supplementation on Probiotic Yoghurt: Physicochemical Properties, Microbial Content, and Sensory Attributes.	Ali HI, Dey M, Alzubaidi AK, Alneamah SJA, Altemimi AB, Pratap-Singh A	Foods	10.3390/foods10102393	2021	*
	Properties of recombinant 4-alpha-glucanotransferase from Bifidobacterium longum subsp. longum JCM 1217 and its application.	Jeong DW, Jeong HM, Shin YJ, Woo SH, Shim JH	Food Sci Biotechnol	10.1007/s10068-019-00707-4	2019	*
	Effect of Non-Dairy Food Matrices on the Survival of Probiotic Bacteria during Storage.	Min M, Bunt CR, Mason SL, Bennett GN, Hussain MA	Microorganisms	10.3390/microorganisms5030043	2017	*
	Beneficial Effect of Bifidobacterium longum ATCC 15707 on Survival Rate of Clostridium difficile Infection in Mice.	Yun B, Song M, Park DJ, Oh S	Korean J Food Sci Anim Resour	10.5851/kosfa.2017.37.3.368	2017	*
	Effect of a probiotic beverage consumption (Enterococcus faecium CRL 183 and Bifidobacterium longum ATCC 15707) in rats with chemically induced colitis.	Celiberto LS, Bedani R, Dejani NN, Ivo de Medeiros A, Sampaio Zuanon JA, Spolidorio LC, Tallarico Adorno MA, Amancio Varesche MB, Carrilho Galvao F, Valentini SR, Font de Valdez G, Rossi EA, Cavallini DCU	PLoS One	10.1371/journal.pone.0175935	2017	*
	Survival of Bifidobacterium longum LMG 13197 microencapsulated in Vegetal or Vegetal-inulin matrix in simulated gastrointestinal fluids and yoghurt.	Amakiri AC, Thantsha MS	Springerplus	10.1186/s40064-016-3010-y	2016	*
	Lyophilised Vegetal BM 297 ATO-Inulin lipid-based synbiotic microparticles containing Bifidobacterium longum LMG 13197: design and characterisation.	Amakiri AC, Kalombo L, Thantsha MS	J Microencapsul	10.3109/02652048.2015.1094534	2015	*
	Effects of Enteric-coated Lactoferrin Tablets Containing Lactobacillus brevis subsp. coagulans on Fecal Properties, Defecation Frequency and Intestinal Microbiota of Japanese Women with a Tendency for Constipation: a Randomized Placebo-controlled Crossover Study.	Suzuki N, Murakoshi M, Ono T, Morishita S, Koide M, Bae MJ, Totsuka M, Shimizu M, Sugiyama K, Nishino H, Iida N	Biosci Microbiota Food Health	10.12938/bmfh.32.13	2013	*
	Quantitative determination of the spatial distribution of pure- and mixed-strain immobilized cells in gel beads by immunofluorescence.	Doleyres Y, Fliss I, Lacroix C	Appl Microbiol Biotechnol	10.1007/s00253-002-1004-x	2002	*
	Preparation of the bifidus milk powder.	Nagawa M, Nakabayashi A, Fujino S	J Dairy Sci	10.3168/jds.S0022-0302(88)79745-3	1988	*
	In vivo Trial of Bifidobacterium longum Revealed the Complex Network Correlations Between Gut Microbiota and Health Promotional Effects.	Kim YT, Kim CH, Kwon JG, Cho JH, Shin YS, Kim HB, Lee JH	Front Microbiol	10.3389/fmicb.2022.886934	2022	*

References

#8612

Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 20219

#20215

Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )

#20218

Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )

#38030 ; Curators of the CIP;
#49449 Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 28903

#66792

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#67770 Japan Collection of Microorganism (JCM) ; Curators of the JCM;

#68371

Automatically annotated from API 50CH acid .

#68382

Automatically annotated from API zym .

#69479

João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .

#69480

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

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Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.: StrainInfo: A central database for resolving microbial strain identifiers . ( DOI 10.60712/SI-ID376921.1 )

#120652 Collection of Institut Pasteur ; Curators of the CIP; CIP 64.62
* These data were automatically processed and therefore are not curated

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