Bifidobacterium longum subsp. longum (DSM 20219, ATCC 15707, NCTC 11818)

Name: Bifidobacterium longum subsp. longum (DSM 20219, ATCC 15707, NCTC 11818)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 1709

Type strain

Strain Designation E194b (Variant a), E194b

Culture col. no. DSM 20219 ATCC 15707 NCTC 11818 CCUG 28903 LMG 13197 13 more

NCBI tax ID(s) 565042 216816 1679

Special Collections DSMZ CCUG JCM KCTC CIP

History <- G. Reuter, E194b (Variant a) ATCC 15707 <-- G. Reuter E194b (Variant a). CIP <- 1964, Lab. Ident. Inst. Pasteur, Paris, France <- M. Sebald, Inst. Pasteur, Paris, France <- H. Werner <- G. Reuter: strain E194b

Links

Bifidobacterium longum subsp. longum E194b is an anaerobe, mesophilic, Gram-positive prokaryote that was isolated from intestine of adult.

Gram-positive rod-shaped anaerobe mesophilic genome sequence 16S sequence

Name and taxonomic classification

SI-ID 376921

NBIMCC 8821,CECT 4503,ATCC 15707,CCRC 11847,CCUG 28903,CECT 4554,CIP 64.62,JCM 1217,LMG 10497,NCFB 2259,NCTC 11818,AS 1.2186,BCRC 11847,DSM 20219,HAMBI 554,KCTC 3128,LMG 13197,NCAIM B.01819,NCIMB 702259,VTT E-96664,NCDO 2259

@ref 20215

Last LPSN update 2026-02-09 11:18:10

Domain Bacteria

Phylum Actinomycetota

Class Actinomycetes

Order Bifidobacteriales

Family Bifidobacteriaceae

Genus Bifidobacterium

Species Bifidobacterium longum subsp. longum

Full scientific name Bifidobacterium longum subsp. longum (Reuter 1963) Mattarelli et al. 2008 (Approved Lists 1980)

BacDive ID	Other strains from **Bifidobacterium longum subsp. longum** (11)	Type strain
161151	B. longum subsp. longum JCM 11340
161152	B. longum subsp. longum JCM 11341
161153	B. longum subsp. longum JCM 11342
161154	B. longum subsp. longum JCM 11343
164160	B. longum subsp. longum JCM 31944
165469	B. longum subsp. longum JCM 7050, LMG 18899
165470	B. longum subsp. longum JCM 7052, CGMCC 1.3013
165471	B. longum subsp. longum JCM 7053, CGMCC 1.3048
165472	B. longum subsp. longum JCM 7055
165473	B. longum subsp. longum JCM 7056
165474	B. longum subsp. longum JCM 7060, CGMCC 1.3049

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Motility	Confidence
120652	positive	rod-shaped
125438				93

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
38030	MEDIUM 20 - for Anaerobic bacteria		Agar (15.000 g);Glucose (5.000 g);Yeast extract (20.000 g);Tryptone (30.000 g);Cysteine hydrochloride (0.500 g);distilled water (1000.000 ml);Hemin solution -M00149 (25.000 ml)
8612	BIFIDOBACTERIUM MEDIUM (DSMZ Medium 58)	Medium recipe at MediaDive	Name: BIFIDOBACTERIUM MEDIUM (DSMZ Medium 58) Composition: Glucose 10.0 g/l Casein peptone 10.0 g/l Bacto Soytone 5.0 g/l Meat extract 5.0 g/l Yeast extract 5.0 g/l L-Cysteine HCl x H2O 0.5 g/l NaHCO3 0.4 g/l NaCl 0.08 g/l MnSO4 x H2O 0.05 g/l KH2PO4 0.04 g/l K2HPO4 0.04 g/l MgSO4 x 7 H2O 0.02 g/l CaCl2 x 2 H2O 0.01 g/l Tween 80 Resazurin Distilled water
120652	CIP Medium 20	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)	Range
8612	positive	growth	37	mesophilic
38030	positive	growth	37	mesophilic
49449	positive	growth	37	mesophilic
67770	positive	growth	37	mesophilic

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
8612	anaerobe
49449	anaerobe
120652	facultative anaerobe
125439	anaerobe	94.7

Spore formation

@ref	Spore formation	Confidence
125439		98.1

Murein

@ref	Murein short key	Type
8612	A21.03	A3ß L-Orn-L-Ser-L-Ala-L-Thr-L-Ala

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68371	27613 ChEBI	amygdalin	-	builds acid from	from API 50CH acid
68371	18305 ChEBI	arbutin	-	builds acid from	from API 50CH acid
68371	17057 ChEBI	cellobiose	-	builds acid from	from API 50CH acid
68371	17108 ChEBI	D-arabinose	-	builds acid from	from API 50CH acid
68371	18333 ChEBI	D-arabitol	-	builds acid from	from API 50CH acid
68371	15824 ChEBI	D-fructose	+	builds acid from	from API 50CH acid
68371	28847 ChEBI	D-fucose	-	builds acid from	from API 50CH acid
68371	12936 ChEBI	D-galactose	+	builds acid from	from API 50CH acid
68371	17634 ChEBI	D-glucose	+	builds acid from	from API 50CH acid
68371	62318 ChEBI	D-lyxose	-	builds acid from	from API 50CH acid
68371	16899 ChEBI	D-mannitol	-	builds acid from	from API 50CH acid
68371	16988 ChEBI	D-ribose	+	builds acid from	from API 50CH acid
68371	17924 ChEBI	D-sorbitol	-	builds acid from	from API 50CH acid
68371	16443 ChEBI	D-tagatose	-	builds acid from	from API 50CH acid
68371	65327 ChEBI	D-xylose	+	builds acid from	from API 50CH acid
68371	17113 ChEBI	erythritol	-	builds acid from	from API 50CH acid
68371	16813 ChEBI	galactitol	-	builds acid from	from API 50CH acid
68371	28066 ChEBI	gentiobiose	-	builds acid from	from API 50CH acid
68371	24265 ChEBI	gluconate	-	builds acid from	from API 50CH acid
68371	17754 ChEBI	glycerol	-	builds acid from	from API 50CH acid
68371	28087 ChEBI	glycogen	-	builds acid from	from API 50CH acid
68371	30849 ChEBI	L-arabinose	+	builds acid from	from API 50CH acid
68371	18403 ChEBI	L-arabitol	-	builds acid from	from API 50CH acid
68371	18287 ChEBI	L-fucose	-	builds acid from	from API 50CH acid
68371	62345 ChEBI	L-rhamnose	-	builds acid from	from API 50CH acid
68371	65328 ChEBI	L-xylose	-	builds acid from	from API 50CH acid
68371	17716 ChEBI	lactose	+	builds acid from	from API 50CH acid
68371	17306 ChEBI	maltose	+	builds acid from	from API 50CH acid
68371	6731 ChEBI	melezitose	+	builds acid from	from API 50CH acid
68371	28053 ChEBI	melibiose	+	builds acid from	from API 50CH acid
68371	320061 ChEBI	methyl alpha-D-glucopyranoside	+	builds acid from	from API 50CH acid
68371	74863 ChEBI	methyl beta-D-xylopyranoside	-	builds acid from	from API 50CH acid
68371	17268 ChEBI	myo-inositol	-	builds acid from	from API 50CH acid
68371	59640 ChEBI	N-acetylglucosamine	-	builds acid from	from API 50CH acid
120652	17632 ChEBI	nitrate	-	reduction
120652	16301 ChEBI	nitrite	-	reduction
68371		Potassium 2-ketogluconate	-	builds acid from	from API 50CH acid
68371	16634 ChEBI	raffinose	+	builds acid from	from API 50CH acid
68371	15963 ChEBI	ribitol	-	builds acid from	from API 50CH acid
68371	17814 ChEBI	salicin	-	builds acid from	from API 50CH acid
68371	17151 ChEBI	xylitol	-	builds acid from	from API 50CH acid

Metabolite production

@ref	Chebi-ID	Metabolite	Production
120652	35581 ChEBI	indole

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
68382	alkaline phosphatase	-	3.1.3.1	from API zym
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	+	3.2.1.22	from API zym
68382	alpha-glucosidase	+	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68382	beta-galactosidase	+	3.2.1.23	from API zym
68382	beta-glucosidase	+	3.2.1.21	from API zym
68382	beta-glucuronidase	-	3.2.1.31	from API zym
120652	catalase	-	1.11.1.6
68382	cystine arylamidase	-	3.4.11.3	from API zym
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
68382	leucine arylamidase	+	3.4.11.1	from API zym
68382	lipase (C 14)	-		from API zym
68382	N-acetyl-beta-glucosaminidase	+	3.2.1.52	from API zym
68382	naphthol-AS-BI-phosphohydrolase	-		from API zym
120652	oxidase	-
68382	trypsin	-	3.4.21.4	from API zym
120652	urease	-	3.5.1.5
68382	valine arylamidase	-		from API zym

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
120652	-	-	+	+	-	+	-	-	-	-	+	-	+	+	-	+	+	+	-	-

API 50CHac

@ref	ControlQ	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
8612	-	-	-	-	+	+	+	-	-	-	+	+	+	-	-	-	-	-	-	-	-	+	-	-	-	+	-	-	+	+	+	+	-	-	+	+	-	-	-	-	+	-	-	-	-	-	-	-	-	-
8612	-	-	-	-	+	+	+	-	-	-	+	+	+	+	+	-	-	-	-	-	+/-	+	-	-	-	-	-	-	+	+	+	+	+	+	+	+	+/-	-	-	-	+/-	-	-	-	-	-	-	-	-	+/-
8612	-	-	-	-	+	+	+	-	-	-	+	+	+	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	+	+	+	+	-	-	+	+	-	-	-	-	+/-	-	-	-	-	-	-	-	-	-
8612	-	-	-	-	+	+	+	-	-	-	+	+	+	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	+	+	+	-	-	-	+	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2
#Host Body-Site	#Gastrointestinal tract

Isolation

@ref	Sample type
8612	intestine of adult
49449	Human intestine,adult
67770	Intestine of adult
120652	Human, Intestine (adult)

Taxonmaps

69479

Global distribution of 16S sequence LC071818 (>99% sequence identity) for Bifidobacterium longum subclade from Microbeatlas

Aquatic Samples	7450
Soil Samples	1795
Animal Samples	197025
Plant Samples	785
Total Samples	207055

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
8612	1	Risk group (German classification) According to TRBA 466
120652	1	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM19655v1 assembly for Bifidobacterium longum subsp. longum JCM 1217	complete	GCA_000196555	565042.3	649633019	565042	99.26
66792	50618_H02 assembly for Bifidobacterium longum NCTC11818	complete	GCA_900637335	216816.359	8117555014	216816	99.08
66792	ASM1713277v1 assembly for Bifidobacterium longum subsp. longum KCTC 3128	complete	GCA_017132775	1679.291		1679	98.08
67770	IMG-taxon 2634166334 annotated assembly for Bifidobacterium longum DSM 20219	contig	GCA_900104835	216816.128	2634166334	216816	77.67
67770	Biflon_sub.lon assembly for Bifidobacterium longum subsp. longum LMG 13197	contig	GCA_000741245	1679.6	2600254982	1679	76.9
124043	ASM5190617v1 assembly for Bifidobacterium longum subsp. longum CICC 6186 = JCM 1217	contig	GCA_051906175			1679	70.65

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Bifidobacterium longum strain ATCC 15707 16S ribosomal RNA gene, partial sequence	M58739	1476	216816
20218	Bifidobacterium longum (ATCC 15707) 16S ribosomal RNA gene, partial	M84781	642	216816
20218	Bifidobacterium longum subsp. longum strain DSM 20219 16S ribosomal RNA gene, partial sequence	HQ012022	940	1679
20218	Bifidobacterium longum subsp. longum JCM 1217 gene for 16S rRNA, partial sequence	AB116313	476	565042
20218	Bifidobacterium longum gene for 16S rRNA, partial sequence, strain: JCM 1217	AB507101	669	565042
20218	Bifidobacterium longum subsp. longum strain KCTC 3128 16S ribosomal RNA gene, partial sequence	GU361823	1477	1679
67770	Bifidobacterium longum subsp. longum gene for 16S ribosomal RNA, partial sequence	AB437359	1507	1679
67770	Bifidobacterium longum subsp. longum gene for 16S ribosomal RNA, partial sequence, strain: JCM 1217	LC071818	1456	1679
124043	Bifidobacterium longum strain VTT E-96664 16S ribosomal RNA gene, partial sequence.	KU321257	1448	216816

GC content

@ref	GC-content (mol%)	Method
8612	61.4
67770	61.4	thermal denaturation, midpoint method (Tm)
67770	61.3	high performance liquid chromatography (HPLC)

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Bifidobacterium longum NCTC11818
NCBI: GCA_900637335

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	no	98.10	no
125439	motility	BacteriaNetⓘ	yes	50.10	no
125439	gram_stain	BacteriaNetⓘ	negative	72.90	no
125439	oxygen_tolerance	BacteriaNetⓘ	anaerobe	94.70	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Bifidobacterium longum subsp. longum JCM 1217 JCM 1217
NCBI: GCA_000196555.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	87.75	no
125438	anaerobic	anaerobicⓘ	yes	83.29	no
125438	aerobic	aerobicⓘ	no	91.96	yes
125438	spore-forming	spore-formingⓘ	no	88.31	no
125438	thermophilic	thermophileⓘ	no	92.97	yes
125438	flagellated	motile2+ⓘ	no	93.00	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	Fexofenadine HCl enhances growth, biofilm, and lactic acid production of Limosilactobacillus reuteri and Bifidobacterium longum: implications for allergy treatment.	Hammouda ZK, Wasfi R, Abdeltawab NF.	BMC Microbiol	10.1186/s12866-025-04130-0	2025
	Uncovering the Probiotic Supplement Landscape: Market Offerings, Sales Patterns, and Future Forecasts Using Machine Learning Approach - A Case Study of Montenegro.	Andela M, Ivan M, Mora D, Arioli S.	Probiotics Antimicrob Proteins	10.1007/s12602-024-10400-6	2025
	Highly efficient CRISPR-Cas9 base editing in Bifidobacterium with bypass of restriction modification systems.	Lin H-C, Hsiao W-C, Hsu Y-C, Lin M-C, Hsu C-C, Zhang MM.	Appl Environ Microbiol	10.1128/aem.01985-24	2025
Pathogenicity	Fermented Soymilk with Probiotic Lactobacilli and Bifidobacterium Strains Ameliorates Dextran-Sulfate-Sodium-Induced Colitis in Rats.	Al Zahrani AJ, Shori AB, Al-Judaibi E.	Nutrients	10.3390/nu16203478	2024
	Ultrasound can increase biofilm formation by Lactiplantibacillus plantarum and Bifidobacterium spp.	Racioppo A, Speranza B, Altieri C, Sinigaglia M, Corbo MR, Bevilacqua A.	Front Microbiol	10.3389/fmicb.2023.1094671	2023
	Modulation of Designed Gut Bacterial Communities by Prebiotics and the Impact of Their Metabolites on Intestinal Cells.	Roupar D, Gonzalez A, Martins JT, Goncalves DA, Teixeira JA, Botelho C, Nobre C.	Foods	10.3390/foods12234216	2023
	Probiotics for the management of irritable bowel syndrome: a systematic review and three-level meta-analysis.	Chen M, Yuan L, Xie CR, Wang XY, Feng SJ, Xiao XY, Zheng H.	Int J Surg	10.1097/js9.0000000000000658	2023
	Plant-Based Fermented Beverages: Nutritional Composition, Sensory Properties, and Health Benefits.	Hidalgo-Fuentes B, de Jesus-Jose E, Cabrera-Hidalgo AJ, Sandoval-Castilla O, Espinosa-Solares T, Gonzalez-Reza RM, Zambrano-Zaragoza ML, Liceaga AM, Aguilar-Toala JE.	Foods	10.3390/foods13060844	2024
	Bifunctional Systems of Amelanchier alnifolia Leaves Extract-Oligosaccharides with Prebiotic and Antidiabetic Benefits	Gosciniak A, Sip A, Szulc P, Cielecka-Piontek J.	Molecules		2025
	Enriched pathways in gut microbiome predict response to immune checkpoint inhibitor treatment across demographic regions and various cancer types.	Cai X, Cho JY, Chen L, Liu Y, Ji F, Salgado K, Ge S, Yang D, Yu H, Shao J, Futreal PA, Sepesi B, Gibbons D, Chen Y, Wang G, Cheng C, Wu M, Zhang J, Hsiao A, Xia T.	iScience	10.1016/j.isci.2025.112162	2025
	Evaluation of Bacterial Diversity and Evolutionary Dynamics of Gut Bifidobacterium longum Isolates Obtained from Older Individuals in Hubei Province, China.	Zhang Z, Hou Q, Wang Y, Xiang F, Guo Z.	Microbiol Spectr	10.1128/spectrum.01442-21	2022
	The Synergistic Effect of Quince Fruit and Probiotics (Lactobacillus and Bifidobacterium) on Reducing Oxidative Stress and Inflammation at the Intestinal Level and Improving Athletic Performance during Endurance Exercise.	Herrera-Rocha KM, Manjarrez-Juanes MM, Larrosa M, Barrios-Payan JA, Rocha-Guzman NE, Macias-Salas A, Gallegos-Infante JA, Alvarez SA, Gonzalez-Laredo RF, Moreno-Jimenez MR.	Nutrients	10.3390/nu15224764	2023
	SEMQuant: Extending Sipros-Ensemble with Match-Between-Runs for Comprehensive Quantitative Metaproteomics.	Zhang B, Feng S, Parajuli M, Xiong Y, Pan C, Guo X.	Bioinform Res Appl	10.1007/978-981-97-5087-0_9	2024
	Growth of Bifidobacterium species is inhibited by free fatty acids and bile salts but not by glycerides.	Perez-Burillo S, Rajakaruna S, Paliy O.	AIMS Microbiol	10.3934/microbiol.2022005	2022
Genetics	Targeted High-Resolution Taxonomic Identification of Bifidobacterium longum subsp. infantis Using Human Milk Oligosaccharide Metabolizing Genes.	Tso L, Bonham KS, Fishbein A, Rowland S, Klepac-Ceraj V.	Nutrients	10.3390/nu13082833	2021
Pathogenicity	Quantifying the varying harvest of fermentation products from the human gut microbiota.	Arnoldini M, Sharma R, Moresi C, Chure G, Chabbey J, Slack E, Cremer J.	Cell	10.1016/j.cell.2025.07.005	2025
Genetics	Probiotic Lactobacillus and Bifidobacterium strains possess safety characteristics, antiviral activities and host adherence factors revealed by genome mining.	Abdelhamid AG, El-Masry SS, El-Dougdoug NK, El-Dougdoug NK.	EPMA J	10.1007/s13167-019-00184-z	2019
	Bifidobacterium beta-Glucosidase Activity and Fermentation of Dietary Plant Glucosides Is Species and Strain Specific.	Modrackova N, Vlkova E, Tejnecky V, Schwab C, Neuzil-Bunesova V.	Microorganisms	10.3390/microorganisms8060839	2020
Phylogeny	Phylogenomic disentangling of the Bifidobacterium longum subsp. infantis taxon.	Tarracchini C, Milani C, Lugli GA, Mancabelli L, Fontana F, Alessandri G, Longhi G, Anzalone R, Viappiani A, Turroni F, van Sinderen D, Ventura M.	Microb Genom	10.1099/mgen.0.000609	2021
	Dietary Melanoidins from Biscuits and Bread Crust Alter the Structure and Short-Chain Fatty Acid Production of Human Gut Microbiota.	Rajakaruna S, Perez-Burillo S, Kramer DL, Rufian-Henares JA, Paliy O.	Microorganisms	10.3390/microorganisms10071268	2022
	Developing standards for the microbiome field.	Amos GCA, Logan A, Anwar S, Fritzsche M, Mate R, Bleazard T, Rijpkema S.	Microbiome	10.1186/s40168-020-00856-3	2020
	Quantitative Detection of Bifidobacterium longum Strains in Feces Using Strain-Specific Primers.	Xiao Y, Wang C, Zhao J, Zhang H, Chen W, Zhai Q.	Microorganisms	10.3390/microorganisms9061159	2021
	Characterization and Exploitation of CRISPR Loci in Bifidobacterium longum.	Hidalgo-Cantabrana C, Crawley AB, Sanchez B, Barrangou R.	Front Microbiol	10.3389/fmicb.2017.01851	2017
	Administration of Bovine Milk Oligosaccharide to Weaning Gnotobiotic Mice Inoculated with a Simplified Infant Type Microbiota.	Jakobsen LMA, Sundekilde UK, Andersen HJ, Kot W, Mejia JLC, Nielsen DS, Hansen AK, Bertram HC.	Microorganisms	10.3390/microorganisms9051003	2021
Metabolism	Fucosyllactose and L-fucose utilization of infant Bifidobacterium longum and Bifidobacterium kashiwanohense.	Bunesova V, Lacroix C, Schwab C.	BMC Microbiol	10.1186/s12866-016-0867-4	2016
	Fermented foods affect the seasonal stability of gut bacteria in an Indian rural population.	Jeyaram K, Lahti L, Tims S, Heilig HGHJ, van Gelder AH, de Vos WM, Smidt H, Zoetendal EG.	Nat Commun	10.1038/s41467-025-56014-6	2025
	Bifidobacteria support optimal infant vaccine responses.	Ryan FJ, Clarke M, Lynn MA, Benson SC, McAlister S, Giles LC, Choo JM, Rossouw C, Ng YY, Semchenko EA, Richard A, Leong LEX, Taylor SL, Blake SJ, Mugabushaka JI, Walker M, Wesselingh SL, Licciardi PV, Seib KL, Tumes DJ, Richmond P, Rogers GB, Marshall HS, Lynn DJ.	Nature	10.1038/s41586-025-08796-4	2025
Metabolism	SIMMER employs similarity algorithms to accurately identify human gut microbiome species and enzymes capable of known chemical transformations.	Bustion AE, Nayak RR, Agrawal A, Turnbaugh PJ, Pollard KS.	Elife	10.7554/elife.82401	2023
	Maternal milk microbiota and oligosaccharides contribute to the infant gut microbiota assembly.	Laursen MF, Pekmez CT, Larsson MW, Lind MV, Yonemitsu C, Larnkjaer A, Molgaard C, Bode L, Dragsted LO, Michaelsen KF, Licht TR, Bahl MI.	ISME Commun	10.1038/s43705-021-00021-3	2021
	Metaproteomics approach to study the functionality of the microbiota in the human infant gastrointestinal tract.	Klaassens ES, de Vos WM, Vaughan EE.	Appl Environ Microbiol	10.1128/aem.01921-06	2007
	Valorization of waste forest biomass toward the production of cello-oligosaccharides with potential prebiotic activity by utilizing customized enzyme cocktails.	Karnaouri A, Matsakas L, Krikigianni E, Rova U, Christakopoulos P.	Biotechnol Biofuels	10.1186/s13068-019-1628-z	2019
Metabolism	Bifidobacterium species associated with breastfeeding produce aromatic lactic acids in the infant gut.	Laursen MF, Sakanaka M, von Burg N, Morbe U, Andersen D, Moll JM, Pekmez CT, Rivollier A, Michaelsen KF, Molgaard C, Lind MV, Dragsted LO, Katayama T, Frandsen HL, Vinggaard AM, Bahl MI, Brix S, Agace W, Licht TR, Roager HM.	Nat Microbiol	10.1038/s41564-021-00970-4	2021
Metabolism	Lactobacillus acidophilus Metabolizes Dietary Plant Glucosides and Externalizes Their Bioactive Phytochemicals.	Theilmann MC, Goh YJ, Nielsen KF, Klaenhammer TR, Barrangou R, Abou Hachem M.	mBio	10.1128/mbio.01421-17	2017
	Multistrain probiotic preparation significantly reduces symptoms of irritable bowel syndrome in a double-blind placebo-controlled study.	Cui S, Hu Y.	Int J Clin Exp Med		2012
	Trophic Interactions of Infant Bifidobacteria and Eubacterium hallii during L-Fucose and Fucosyllactose Degradation.	Schwab C, Ruscheweyh HJ, Bunesova V, Pham VT, Beerenwinkel N, Lacroix C.	Front Microbiol	10.3389/fmicb.2017.00095	2017
Pathogenicity	Inhibitory activity spectrum of reuterin produced by Lactobacillus reuteri against intestinal bacteria.	Cleusix V, Lacroix C, Vollenweider S, Duboux M, Le Blay G.	BMC Microbiol	10.1186/1471-2180-7-101	2007
Phylogeny	INC-Seq: accurate single molecule reads using nanopore sequencing.	Li C, Chng KR, Boey EJ, Ng AH, Wilm A, Nagarajan N.	Gigascience	10.1186/s13742-016-0140-7	2016
Metabolism	Microbial short-chain fatty acids modulate CD8⁺ T cell responses and improve adoptive immunotherapy for cancer.	Luu M, Riester Z, Baldrich A, Reichardt N, Yuille S, Busetti A, Klein M, Wempe A, Leister H, Raifer H, Picard F, Muhammad K, Ohl K, Romero R, Fischer F, Bauer CA, Huber M, Gress TM, Lauth M, Danhof S, Bopp T, Nerreter T, Mulder IE, Steinhoff U, Hudecek M, Visekruna A.	Nat Commun	10.1038/s41467-021-24331-1	2021
Metabolism	Hydrolytic fate of deoxynivalenol-3-glucoside during digestion.	Berthiller F, Krska R, Domig KJ, Kneifel W, Juge N, Schuhmacher R, Adam G.	Toxicol Lett	10.1016/j.toxlet.2011.08.006	2011
	Development of an in vitro Model of Human Gut Microbiota for Screening the Reciprocal Interactions With Antibiotics, Drugs, and Xenobiotics.	El Houari A, Ecale F, Mercier A, Crapart S, Laparre J, Soulard B, Ramnath M, Berjeaud JM, Rodier MH, Crepin A.	Front Microbiol	10.3389/fmicb.2022.828359	2022
	Differences in gut microbiota composition between obese and lean children: a cross-sectional study.	Bervoets L, Van Hoorenbeeck K, Kortleven I, Van Noten C, Hens N, Vael C, Goossens H, Desager KN, Vankerckhoven V.	Gut Pathog	10.1186/1757-4749-5-10	2013
Metabolism	Bifidobacterium longum requires a fructokinase (Frk; ATP:D-fructose 6-phosphotransferase, EC 2.7.1.4) for fructose catabolism.	Caescu CI, Vidal O, Krzewinski F, Artenie V, Bouquelet S.	J Bacteriol	10.1128/jb.186.19.6515-6525.2004	2004
Cultivation	A new selective medium for Bifidobacterium spp.	Nebra Y, Blanch AR.	Appl Environ Microbiol	10.1128/aem.65.11.5173-5176.1999	1999
Metabolism	Methotrexate impacts conserved pathways in diverse human gut bacteria leading to decreased host immune activation.	Nayak RR, Alexander M, Deshpande I, Stapleton-Gray K, Rimal B, Patterson AD, Ubeda C, Scher JU, Turnbaugh PJ.	Cell Host Microbe	10.1016/j.chom.2020.12.008	2021
Genetics	Genome-Based Taxonomic Classification of the Phylum Actinobacteria.	Nouioui I, Carro L, Garcia-Lopez M, Meier-Kolthoff JP, Woyke T, Kyrpides NC, Pukall R, Klenk HP, Goodfellow M, Goker M.	Front Microbiol	10.3389/fmicb.2018.02007	2018
	Microarray analysis and barcoded pyrosequencing provide consistent microbial profiles depending on the source of human intestinal samples.	van den Bogert B, de Vos WM, Zoetendal EG, Kleerebezem M.	Appl Environ Microbiol	10.1128/aem.02477-10	2011
Enzymology	Quantification of intestinal bacterial populations by real-time PCR with a universal primer set and minor groove binder probes: a global approach to the enteric flora.	Ott SJ, Musfeldt M, Ullmann U, Hampe J, Schreiber S.	J Clin Microbiol	10.1128/jcm.42.6.2566-2572.2004	2004
	Extracellular vesicles of Bifidobacterium longum reverse the acquired carboplatin resistance in ovarian cancer cells via p53 phosphorylation on Ser15.	Fan YL, Jin JX, Zhu J, Ruan HB, Huang JQ.	Kaohsiung J Med Sci	10.1002/kjm2.12837	2024
	Exo- and Endo-1,5-alpha-L-Arabinanases and Prebiotic Arabino-Oligosaccharides Production.	Ju YR, Im SB, Jung DE, Son MJ, Park CY, Jeon MH, Hwang JH, Lee SJ, Kim TJ.	J Microbiol Biotechnol	10.4014/jmb.2412.12052	2025
	Colonization of engineered bacteria enhanced lipid nanomedicine accumulation in tumors for sonodynamic immunotherapy.	Xu Y, Cai X, Wu J, Zheng Y, Wang Y.	Mater Today Bio	10.1016/j.mtbio.2025.101943	2025
	Gut Microbe Fermentation of Moringa oleifera Leaf Extract Increases Measurable Polyphenols and Improves Barrier Function in a Cell Culture Model.	Kable ME, Storms DH, Alkan Z, Muriki M, DeVries D, Waterman C, Lemay DG.	Microbiologyopen	10.1002/mbo3.70068	2025
	Rehydration Beverages Made from Quercus sideroxyla Infusion, Probiotics, and Prebiotics: Antioxidant and Anti-Inflammatory Potential.	Salas-Ramirez CA, Moreno-Jimenez MR, Rocha-Guzman NE, Gallegos-Infante JA, Gonzalez-Laredo RF, Gonzalez Herrera SM, Gonzalez-Mercado ME, Herrera-Rocha KM, Chairez-Ramirez MH.	Foods	10.3390/foods14050837	2025
	Optimizing Precision Probiotics for Mitigating Graft-Versus-Host Disease.	Ebigbo N, Long A, Do P, Coughlin L, Poulides N, Jewell T, Gan S, Zhan X, Koh AY.	Microorganisms	10.3390/microorganisms13040706	2025
	Emerging Roles of the Gut Microbiome in Musculoskeletal Injury and Repair.	Roberts JL, Park CC.	Microorganisms	10.3390/microorganisms13092193	2025
Pathogenicity	Bifidobacterium longum subsp. longum BG-L47 boosts growth and activity of Limosilactobacillus reuteri DSM 17938 and its extracellular membrane vesicles.	Ermann Lundberg L, Pallabi Mishra P, Liu P, Forsberg MM, Sverremark-Ekstrom E, Grompone G, Hakansson S, Linninge C, Roos S.	Appl Environ Microbiol	10.1128/aem.00247-24	2024
Pathogenicity	Assessment of the feed additive consisting of a strain belonging to Eggerthellaceae family (DSM 11798) for pigs and all avian species (1m01) for the renewal of its authorisation (BIOMIN GmbH).	EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Villa RE, Azimonti G, Bonos E, Christensen H, Durjava M, Dusemund B, Gehring R, Glandorf B, Kouba M, Lopez-Alonso M, Marcon F, Nebbia C, Pechova A, Prieto-Maradona M, Rohe I, Theodoridou K, Mayo B, Anguita M, Galobart J, Ortuno J, Pizzo F, Brozzi R.	EFSA J	10.2903/j.efsa.2025.9360	2025
Pathogenicity	Bifidobacteria and Celiac Disease: Mechanisms of Probiotic Action in Reducing Gluten-Induced Cytotoxicity and Inflammation.	Scherer TC, De Marco I, Ferreira NRC, Pimentel TC, Magnani M, Hassemer GS, Nascimento ABD, Verruck S.	Mol Nutr Food Res	10.1002/mnfr.70222	2025
	Rapid discrimination of Bifidobacterium longum subspecies based on MALDI-TOF MS and machine learning.	Liu K, Wang Y, Zhao M, Xue G, Wang A, Wang W, Xu L, Chen J.	Front Microbiol	10.3389/fmicb.2023.1297451	2023
	Biosynthesis and health promoting traits of green synthesized cobalt oxide nanoparticles.	Moawad R, Abdallah Y, Mohany M, Al-Rejaie SS, Djurasevic S, Ramadan MF, Mousa AB.	Sci Rep	10.1038/s41598-024-82679-y	2025
	Featured Prebiotic Agent: The Roles and Mechanisms of Direct and Indirect Prebiotic Activities of Lactoferrin and Its Application in Disease Control.	Liu ZS, Chen PW.	Nutrients	10.3390/nu15122759	2023
	A low-cost, easy-to-use prototype bioreactor model for the investigation of human gut microbiota: validation using a prebiotic treatment.	Agrinier AL, Pilon G, Marette A.	Front Microbiol	10.3389/fmicb.2024.1250366	2024
	Abundance of Bifidobacterium species in the infant gut microbiota and associations with maternal-infant characteristics in Dhaka, Bangladesh.	Freitas AC, Li G, Shawon J, Qamar H, Pell LG, Kabir M, Oduaran OH, Puebla-Barragan S, Bassani DG, O'Callaghan KM, Onuora JC, Loutet MG, Heasley C, Starke CWE, Mahmud AA, Hamer DH, Pullenayegum E, Hossain MI, Siddiqui MM, Islam MS, Sherman PM, Shah PS, Gaffar SMA, Sultana S, Morris SK, Ahmed T, Haque R, Sarker SA, Roth DE.	mSphere	10.1128/msphere.00314-25	2025
	Screening canine sources for novel antimicrobials reveals the circular broad-spectrum bacteriocin, caledonicin, produced by Staphylococcus caledonicus.	O'Connor M, O'Connor PM, Hourigan D, Murray E, de Farias FM, Field D, Hill C, Ross RP.	Front Microbiol	10.3389/fmicb.2024.1470988	2024
	Dual mode imaging guided multi-functional bio-targeted oxygen production probes for tumor therapy.	Wang Y, Zhang Z, Ren L, Luo Y, Wang Q, Zou J.	J Nanobiotechnology	10.1186/s12951-023-01901-7	2023
	Bifidobacterium exopolysaccharides: new insights into engineering strategies, physicochemical functions, and immunomodulatory effects on host health.	Sadeghi M, Haghshenas B, Nami Y.	Front Microbiol	10.3389/fmicb.2024.1396308	2024
Metabolism	Structure-dependent stimulation of gut bacteria by arabinoxylo-oligosaccharides (AXOS): a review.	Leschonski KP, Mortensen MS, Hansen LBS, Krogh KBRM, Kabel MA, Laursen MF.	Gut Microbes	10.1080/19490976.2024.2430419	2024
	Probiotic Properties of Bifidobacterium longum KABP042 and Pediococcus pentosaceus KABP041 Show Potential to Counteract Functional Gastrointestinal Disorders in an Observational Pilot Trial in Infants.	Asto E, Huedo P, Altadill T, Aguilo Garcia M, Sticco M, Perez M, Espadaler-Mazo J.	Front Microbiol	10.3389/fmicb.2021.741391	2021
	Structural, antioxidant, prebiotic and anti-inflammatory properties of pectic oligosaccharides hydrolyzed from okra pectin by Fenton reaction	Yeung YK, Kang YR, So BR, Jung SK, Chang YH.	Food hydrocolloids.	10.1016/j.foodhyd.2021.106779	2021
	The protective role of prebiotics and probiotics on diarrhea and gut damage in the rotavirus-infected piglets.	Yang H, Fan X, Mao X, Yu B, He J, Yan H, Wang J.	J Anim Sci Biotechnol	10.1186/s40104-024-01018-3	2024
	Bifidobacterium longum supplementation improves age-related delays in fracture repair.	Roberts JL, Golloshi M, Harding DB, Conduah M, Liu G, Drissi H.	Aging Cell	10.1111/acel.13786	2023
	Exploring Beneficial Properties of Haskap Berry Leaf Compounds for Gut Health Enhancement.	Sip S, Sip A, Szulc P, Selwet M, Zarowski M, Czerny B, Cielecka-Piontek J.	Antioxidants (Basel)	10.3390/antiox13030357	2024
	Butyrate modulates mucin secretion and bacterial adherence in LoVo cells via MAPK signaling.	Jung TH, Han KS, Park JH, Hwang HJ.	PLoS One	10.1371/journal.pone.0269872	2022
	Unveiling the inhibition mechanism of Clostridioides difficile by Bifidobacterium longum via multiomics approach.	Jo SH, Jeon HJ, Song WS, Lee JS, Kwon JE, Park JH, Kim YR, Kim MG, Baek JH, Kwon SY, Kim JS, Yang YH, Kim YG.	Front Microbiol	10.3389/fmicb.2023.1293149	2023
	A systematic review and meta-analysis of the effects of probiotics on bone outcomes in rodent models.	Yumol JL, Gittings W, de Souza RJ, Ward WE.	J Bone Miner Res	10.1093/jbmr/zjae187	2024
	Structural characteristics, physicochemical properties and prebiotic potential of modified dietary fibre from the basal part of bamboo shoot	Fang D, Wang Q, Chen C, Li Z, Li S, Chen W, Zheng Y.	International journal of food science and technology.	10.1111/ijfs.14709	2021
	Study of the biosynthesis and functionality of polyphosphate in Bifidobacterium longum KABP042.	Alcantara C, Perez M, Huedo P, Altadill T, Espadaler-Mazo J, Arques JL, Zuniga M, Monedero V.	Sci Rep	10.1038/s41598-023-38082-0	2023
Pathogenicity	The Anti-Inflammatory and Curative Exponent of Probiotics: A Comprehensive and Authentic Ingredient for the Sustained Functioning of Major Human Organs.	Virk MS, Virk MA, He Y, Tufail T, Gul M, Qayum A, Rehman A, Rashid A, Ekumah JN, Han X, Wang J, Ren X.	Nutrients	10.3390/nu16040546	2024
	The Impact of Fermented Dairy Products and Probiotics on Bone Health Improvement.	Bashir HH, Hasnain MA, Abbas A, Lee JH, Moon GS.	Food Sci Anim Resour	10.5851/kosfa.2025.e7	2025
	Hormonal drugs: Influence on growth, biofilm formation, and adherence of selected gut microbiota.	Hammouda ZK, Wasfi R, Abdeltawab NF.	Front Cell Infect Microbiol	10.3389/fcimb.2023.1147585	2023
	In vitro inhibitory activity of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 alone or in combination against bacterial and Candida reference strains and clinical isolates.	Inturri R, Trovato L, Volti GL, Oliveri S, Blandino G.	Heliyon	10.1016/j.heliyon.2019.e02891	2019
	Bifidobacterium breve PRL2020: Antibiotic-Resistant Profile and Genomic Detection of Antibiotic Resistance Determinants.	Di Pierro F, Campedelli I, De Marta P, Fracchetti F, Del Casale A, Cavecchia I, Matera M, Cazzaniga M, Bertuccioli A, Guasti L, Zerbinati N.	Microorganisms	10.3390/microorganisms11071649	2023
Pathogenicity	The Cooperation of Bifidobacterium longum and Active Vitamin D3 on Innate Immunity in Salmonella Colitis Mice via Vitamin D Receptor.	Huang FC, Huang SC.	Microorganisms	10.3390/microorganisms9091804	2021
	Prebiotic Oligosaccharides in Skin Health: Benefits, Mechanisms, and Cosmetic Applications.	Zeng M, Li Y, Cheng J, Wang J, Liu Q.	Antioxidants (Basel)	10.3390/antiox14060754	2025
	Comparison of fidaxomicin, thuricin CD, vancomycin and nisin highlights the narrow spectrum nature of thuricin CD.	Walsh L, Lavelle A, O'Connor PM, Hill C, Ross RP.	Gut Microbes	10.1080/19490976.2024.2342583	2024
	Bifidobacterium Longum: Protection against Inflammatory Bowel Disease.	Yao S, Zhao Z, Wang W, Liu X.	J Immunol Res	10.1155/2021/8030297	2021
	Metabolic Effects of Bovine Milk Oligosaccharides on Selected Commensals of the Infant Microbiome-Commensalism and Postbiotic Effects.	Jakobsen LMA, Maldonado-Gomez MX, Sundekilde UK, Andersen HJ, Nielsen DS, Bertram HC.	Metabolites	10.3390/metabo10040167	2020
	Extraction and Characterization of Cocoa Bean Shell Cell Wall Polysaccharides.	Younes A, Karboune S, Liu L, Andreani ES, Dahman S.	Polymers (Basel)	10.3390/polym15030745	2023
	Alginate encapsulation improves probiotics survival in carbonated sodas and beers.	Tan LL, Ang KL, Loo SCJ.	PLoS One	10.1371/journal.pone.0283745	2023
	Synergistic and off-target effects of bacteriocins in a simplified human intestinal microbiome: implications for Clostridioides difficile infection control.	Rios Colombo NS, Paul Ross R, Hill C.	Gut Microbes	10.1080/19490976.2025.2451081	2025
	Variation in characterization and probiotic activities of polysaccharides from litchi pulp fermented for different times.	He C, Zhang R, Jia X, Dong L, Ma Q, Zhao D, Sun Z, Zhang M, Huang F.	Front Nutr	10.3389/fnut.2022.993828	2022
	Cross-feeding interactions between human gut commensals belonging to the Bacteroides and Bifidobacterium genera when grown on dietary glycans.	Fernandez-Julia P, Commane DM, van Sinderen D, Munoz-Munoz J.	Microbiome Res Rep	10.20517/mrr.2021.05	2022
Metabolism	Carbohydrate-controlled serine protease inhibitor (serpin) production in Bifidobacterium longum subsp. longum.	Duboux S, Golliard M, Muller JA, Bergonzelli G, Bolten CJ, Mercenier A, Kleerebezem M.	Sci Rep	10.1038/s41598-021-86740-y	2021
	Recent Development of Probiotic Bifidobacteria for Treating Human Diseases.	Chen J, Chen X, Ho CL.	Front Bioeng Biotechnol	10.3389/fbioe.2021.770248	2021
	Isolation and purification of Tartary buckwheat polysaccharides and their effect on gut microbiota.	Xiang Y, Cao YN, Yang SH, Ren YH, Zhao G, Li Q, Li H, Peng LX.	Food Sci Nutr	10.1002/fsn3.3072	2023
Metabolism	Ingestion of Bifidobacterium longum changes miRNA levels in the brains of mice.	DeVries L, Horstman C, Fossell M, Carlson C.	PLoS One	10.1371/journal.pone.0249817	2021
	Antimicrobial Resistance of Seventy Lactic Acid Bacteria Isolated from Commercial Probiotics in Korea.	Shin E, Paek JJ, Lee Y.	J Microbiol Biotechnol	10.4014/jmb.2210.10041	2023
	Evaluation of the microbiota-sparing properties of the anti-staphylococcal antibiotic afabicin.	Nowakowska J, Cameron DR, De Martino A, Kuhn J, Le Fresne-Languille S, Leuillet S, Amouzou Y, Wittke F, Carton T, Le Vacon F, Chaves RL, Nicolas-Metral V, Vuagniaux G.	J Antimicrob Chemother	10.1093/jac/dkad181	2023
	A postbiotic consisting of heat-treated lactobacilli has a bifidogenic effect in pure culture and in human fermented faecal communities.	Warda AK, Clooney AG, Ryan F, de Almeida Bettio PH, Di Benedetto G, Ross RP, Hill C.	Appl Environ Microbiol	10.1128/aem.02459-20	2021
	The Antimicrobial Effect of Various Single-Strain and Multi-Strain Probiotics, Dietary Supplements or Other Beneficial Microbes against Common Clinical Wound Pathogens.	Fijan S, Kocbek P, Steyer A, Vodicar PM, Strauss M.	Microorganisms	10.3390/microorganisms10122518	2022
	Growth and survival of Bifidobacterium breve and Bifidobacterium longum in various sugar systems with fructooligosaccharide supplementation.	Parhi P, Song KP, Choo WS.	J Food Sci Technol	10.1007/s13197-022-05361-z	2022
	Enhanced Viability and Anti-rotavirus Effect of Bifidobacterium longum and Lactobacillus plantarum in Combination With Chlorella sorokiniana in a Dairy Product.	Cantu-Bernal S, Dominguez-Gamez M, Medina-Peraza I, Aros-Uzarraga E, Ontiveros N, Flores-Mendoza L, Gomez-Flores R, Tamez-Guerra P, Gonzalez-Ochoa G.	Front Microbiol	10.3389/fmicb.2020.00875	2020
	Multi-omics analysis of the effects of dietary changes and probiotics on diet-induced obesity.	Jiang S, Su Y, Wang Q, Lv L, Xue C, Xu L, Li L.	Curr Res Food Sci	10.1016/j.crfs.2023.100435	2023
	Susceptibility to inflammatory bowel diseases promotes invasive carcinomas in a murine model of ATF6-driven colon cancer.	Kovilein J, Sorbie A, Khaloian S, Kuntzel V, von Stern M, Ahmed M, Jarosch S, Remke M, Metwaly A, Reuss EM, Busch DH, Allez M, Steiger K, Schraml B, Coleman OI, Haller D.	J Crohns Colitis	10.1093/ecco-jcc/jjaf102	2025
	The Effects of Stevia Consumption on Gut Bacteria: Friend or Foe?	Kasti AN, Nikolaki MD, Synodinou KD, Katsas KN, Petsis K, Lambrinou S, Pyrousis IA, Triantafyllou K.	Microorganisms	10.3390/microorganisms10040744	2022
	Streptococcus thermophilus: A Source of Postbiotics Displaying Anti-Inflammatory Effects in THP 1 Macrophages.	Allouche R, Hafeez Z, Dary-Mourot A, Genay M, Miclo L.	Molecules	10.3390/molecules29071552	2024
	Beyond the gut: decoding the gut-immune-brain axis in health and disease.	Park JC, Chang L, Kwon HK, Im SH.	Cell Mol Immunol	10.1038/s41423-025-01333-3	2025
	Advancements and obstacles in acrylamide detection and mitigation in food products.	Lupaescu AV, Oroian M.	Food Chem X	10.1016/j.fochx.2025.102593	2025
	Psychobiotics in Depression: Sources, Metabolites, and Treatment-A Systematic Review.	Sliwka A, Polak-Berecka M, Zdybel K, Zelek-Molik A, Wasko A.	Nutrients	10.3390/nu17132139	2025
Metabolism	Synthetic Microbiomes on the Rise-Application in Deciphering the Role of Microbes in Host Health and Disease.	Bolsega S, Bleich A, Basic M.	Nutrients	10.3390/nu13114173	2021
	Synthetic microbial consortia for the treatment of Clostridioides difficile infection in mice model.	Liu J, Zhu W, Lessing DJ, Chu W.	Microb Biotechnol	10.1111/1751-7915.14333	2023
	Interactions between Blastocystis subtype ST4 and gut microbiota in vitro.	Deng L, Tan KSW.	Parasit Vectors	10.1186/s13071-022-05194-x	2022
	Evaluation of Modulatory Activities of Lactobacillus crispatus Strains in the Context of the Vaginal Microbiota.	Argentini C, Fontana F, Alessandri G, Lugli GA, Mancabelli L, Ossiprandi MC, van Sinderen D, Ventura M, Milani C, Turroni F.	Microbiol Spectr	10.1128/spectrum.02733-21	2022
	Bifidobacterium longum subsp. infantis ATCC 15697 and Goat Milk Oligosaccharides Show Synergism In Vitro as Anti-Infectives against Campylobacter jejuni.	Quinn EM, Slattery H, Walsh D, Joshi L, Hickey RM.	Foods	10.3390/foods9030348	2020
	Two-Stage Interpretation of Changes in TEER of Intestinal Epithelial Layers Protected by Adhering Bifidobacteria During E. coli Challenges.	Yuan L, van der Mei HC, Busscher HJ, Peterson BW.	Front Microbiol	10.3389/fmicb.2020.599555	2020
	The synthesis of extracellular vesicles by the protistan parasite Blastocystis.	Leonardi SS, Koh EY, Deng L, Huang C, Tong L, Wang JW, Tan KS.	Front Cell Infect Microbiol	10.3389/fcimb.2022.1019789	2022
Pathogenicity	Novel Antifungal Activity of Q-Griffithsin, a Broad-Spectrum Antiviral Lectin.	Nabeta HW, Kouokam JC, Lasnik AB, Fuqua JL, Palmer KE.	Microbiol Spectr	10.1128/spectrum.00957-21	2021
	Study of the Efficacy of Probiotic Bacteria to Reduce Acrylamide in Food and In Vitro Digestion.	Choi SM, Yang L, Chang Y, Chu IK, Dong N.	Foods	10.3390/foods11091263	2022
	Delivery Strategies of Probiotics from Nano- and Microparticles: Trends in the Treatment of Inflammatory Bowel Disease-An Overview.	Lopes SA, Roque-Borda CA, Duarte JL, Di Filippo LD, Borges Cardoso VM, Pavan FR, Chorilli M, Meneguin AB.	Pharmaceutics	10.3390/pharmaceutics15112600	2023
	Experimental Study of Tumor Therapy Mediated by Multimodal Imaging Based on a Biological Targeting Synergistic Agent.	Wang Y, Chen C, Luo Y, Xiong J, Tang Y, Yang H, Wang L, Jiang F, Gao X, Xu D, Li H, Wang Q, Zou J.	Int J Nanomedicine	10.2147/ijn.s238398	2020
	In Vitro Antimicrobial Activity and Probiotic Potential of Bifidobacterium and Lactobacillus against Species of Clostridium.	Monteiro CRAV, do Carmo MS, Melo BO, Alves MS, Dos Santos CI, Monteiro SG, Bomfim MRQ, Fernandes ES, Monteiro-Neto V.	Nutrients	10.3390/nu11020448	2019
Metabolism	Feasibility between Bifidobacteria Targeting and Changes in the Acoustic Environment of tumor Tissue for Synergistic HIFU.	Xu D, Zou W, Luo Y, Gao X, Jiang B, Wang Y, Jiang F, Xiong J, Chen C, Tang Y, Qiao H, Li H, Zou J.	Sci Rep	10.1038/s41598-020-64661-6	2020
	Protective Effects of Bifidobacterial Strains Against Toxigenic Clostridium difficile.	Wei Y, Yang F, Wu Q, Gao J, Liu W, Liu C, Guo X, Suwal S, Kou Y, Zhang B, Wang Y, Zheng K, Tang R.	Front Microbiol	10.3389/fmicb.2018.00888	2018
	Purification of Polysaccharide Produced by the Haploid Yeast Strain of Tremella sanguinea and Its Antioxidant and Prebiotic Activities.	Liu Y, Chen S, Zhang J, Gao M, Li L.	Molecules	10.3390/molecules28145391	2023
Metabolism	Lactobacillus acidophilus and Bifidobacterium longum supernatants upregulate the serotonin transporter expression in intestinal epithelial cells.	Cao YN, Feng LJ, Wang BM, Jiang K, Li S, Xu X, Wang WQ, Zhao JW, Wang YM.	Saudi J Gastroenterol	10.4103/sjg.sjg_333_17	2018
Metabolism	Lactoferrin Metal Saturation-Which Form Is the Best for Neonatal Nutrition?	Majka G, Pilarczyk-Zurek M, Baranowska A, Skowron B, Strus M.	Nutrients	10.3390/nu12113340	2020
	General Commentary on: Alternatives to Antibiotic Growth Promoters in Animals.	Anonye BO.	Front Vet Sci	10.3389/fvets.2016.00074	2016
Pathogenicity	Neuroimmunomodulation by gut bacteria: Focus on inflammatory bowel diseases.	Aggarwal S, Ranjha R, Paul J.	World J Gastrointest Pathophysiol	10.4291/wjgp.v12.i3.25	2021
Metabolism	tuf Gene Sequence Variation in Bifidobacterium longum subsp. infantis Detected in the Fecal Microbiota of Chinese Infants.	Lawley B, Centanni M, Watanabe J, Sims I, Carnachan S, Broadbent R, Lee PS, Wong KH, Tannock GW.	Appl Environ Microbiol	10.1128/aem.00336-18	2018
	Characterization of an Alkaline GH49 Dextranase from Marine Bacterium Arthrobacter oxydans KQ11 and Its Application in the Preparation of Isomalto-Oligosaccharide.	Liu H, Ren W, Ly M, Li H, Wang S.	Mar Drugs	10.3390/md17080479	2019
Metabolism	Mapping Interactions of Microbial Metabolites with Human G-Protein-Coupled Receptors.	Colosimo DA, Kohn JA, Luo PM, Piscotta FJ, Han SM, Pickard AJ, Rao A, Cross JR, Cohen LJ, Brady SF.	Cell Host Microbe	10.1016/j.chom.2019.07.002	2019
Metabolism	Safety Evaluations of Bifidobacterium bifidum BGN4 and Bifidobacterium longum BORI.	Kim MJ, Ku S, Kim SY, Lee HH, Jin H, Kang S, Li R, Johnston TV, Park MS, Ji GE.	Int J Mol Sci	10.3390/ijms19051422	2018
	Maternal fiber deprivation alters microbiota in offspring, resulting in low-grade inflammation and predisposition to obesity.	Zou J, Ngo VL, Wang Y, Wang Y, Gewirtz AT.	Cell Host Microbe	10.1016/j.chom.2022.10.014	2023
	Immunomodulatory Effect of Gut Microbiota-Derived Bioactive Peptides on Human Immune System from Healthy Controls and Patients with Inflammatory Bowel Disease.	Fernandez-Tome S, Marin AC, Ortega Moreno L, Baldan-Martin M, Mora-Gutierrez I, Lanas-Gimeno A, Moreno-Monteagudo JA, Santander C, Sanchez B, Chaparro M, Gisbert JP, Bernardo D.	Nutrients	10.3390/nu11112605	2019
Phylogeny	Identification of species belonging to the Bifidobacterium genus by PCR-RFLP analysis of a hsp60 gene fragment.	Baffoni L, Stenico V, Strahsburger E, Gaggia F, Di Gioia D, Modesto M, Mattarelli P, Biavati B.	BMC Microbiol	10.1186/1471-2180-13-149	2013
	A study of the prebiotic effect of lactulose at low dosages in healthy Japanese women.	Sakai Y, Seki N, Hamano H, Ochi H, Abe F, Shimizu F, Masuda K, Iino H.	Biosci Microbiota Food Health	10.12938/bmfh.18-013	2019
Metabolism	Complementary Mechanisms for Degradation of Inulin-Type Fructans and Arabinoxylan Oligosaccharides among Bifidobacterial Strains Suggest Bacterial Cooperation.	Riviere A, Selak M, Geirnaert A, Van den Abbeele P, De Vuyst L.	Appl Environ Microbiol	10.1128/aem.02893-17	2018
	Inhibitory Effect of Fermented Flammulina velutipes Polysaccharides on Mice Intestinal Inflammation.	Ma S, Xu J, Lai T, Xu W, Zhang J, Zhang H, Zhang W.	Front Nutr	10.3389/fnut.2022.934073	2022
	Complex Bacterial Consortia Reprogram the Colitogenic Activity of Enterococcus faecalis in a Gnotobiotic Mouse Model of Chronic, Immune-Mediated Colitis.	Lengfelder I, Sava IG, Hansen JJ, Kleigrewe K, Herzog J, Neuhaus K, Hofmann T, Sartor RB, Haller D.	Front Immunol	10.3389/fimmu.2019.01420	2019
	Experimental Study of Retention on the Combination of Bifidobacterium with High-Intensity Focused Ultrasound (HIFU) Synergistic Substance in Tumor Tissues.	Gao X, Zou W, Jiang B, Xu D, Luo Y, Xiong J, Yan S, Wang Y, Tang Y, Chen C, Li H, Qiao H, Wang Q, Zou J.	Sci Rep	10.1038/s41598-019-42832-4	2019
	Prebiotic potential of Agave angustifolia Haw fructans with different degrees of polymerization.	Velazquez-Martinez JR, Gonzalez-Cervantes RM, Hernandez-Gallegos MA, Mendiola RC, Aparicio AR, Ocampo ML.	Molecules	10.3390/molecules190812660	2014
Proteome	In Silico Screening of the Human Gut Metaproteome Identifies Th17-Promoting Peptides Encrypted in Proteins of Commensal Bacteria.	Hidalgo-Cantabrana C, Moro-Garcia MA, Blanco-Miguez A, Fdez-Riverola F, Lourenco A, Alonso-Arias R, Sanchez B.	Front Microbiol	10.3389/fmicb.2017.01726	2017
Pathogenicity	Characterization, Antioxidant and Anti-Inflammation Capacities of Fermented Flammulina velutipes Polyphenols.	Ma S, Zhang H, Xu J.	Molecules	10.3390/molecules26206205	2021
Metabolism	Bioaccessible antioxidants in milk fermented by Bifidobacterium longum subsp. longum strains.	Gagnon M, Savard P, Riviere A, LaPointe G, Roy D.	Biomed Res Int	10.1155/2015/169381	2015
Pathogenicity	Effect of probiotics supplementation on bone mineral content and bone mass density.	Parvaneh K, Jamaluddin R, Karimi G, Erfani R.	ScientificWorldJournal	10.1155/2014/595962	2014
	Impact of bacteriocin-producing strains on bacterial community composition in a simplified human intestinal microbiota.	Rios Colombo NS, Perez-Ibarreche M, Draper LA, O'Connor PM, Field D, Ross RP, Hill C.	Front Microbiol	10.3389/fmicb.2023.1290697	2023
	Prebiotic Potential and Chemical Composition of Seven Culinary Spice Extracts.	Lu QY, Summanen PH, Lee RP, Huang J, Henning SM, Heber D, Finegold SM, Li Z.	J Food Sci	10.1111/1750-3841.13792	2017
	Biodiversity in nutrients and biological activities of 14 highbush blueberry (Vaccinium corymbosum L.) cultivars.	Lachowicz-Wisniewska S, Pratap-Singh A, Ochmian I, Kapusta I, Kotowska A, Pluta S.	Sci Rep	10.1038/s41598-024-71114-x	2024
	Interactions between a pathogenic Blastocystis subtype and gut microbiota: in vitro and in vivo studies.	Yason JA, Liang YR, Png CW, Zhang Y, Tan KSW.	Microbiome	10.1186/s40168-019-0644-3	2019
Phylogeny	Biodiversity and Physiological Characteristics of Novel Faecalibacterium prausnitzii Strains Isolated from Human Feces.	Hu W, Gao W, Liu Z, Fang Z, Zhao J, Zhang H, Lu W, Chen W.	Microorganisms	10.3390/microorganisms10020297	2022
	Four Types of TiO₂ Reduced the Growth of Selected Lactic Acid Bacteria Strains.	Baranowska-Wojcik E, Gustaw K, Szwajgier D, Oleszczuk P, Pawlikowska-Pawlega B, Pawelec J, Kapral-Piotrowska J.	Foods	10.3390/foods10050939	2021
Pathogenicity	The botanical origin and antioxidant, anti-BACE1 and antiproliferative properties of bee pollen from different regions of South Korea.	Zou Y, Hu J, Huang W, Zhu L, Shao M, Dordoe C, Ahn YJ, Wang D, Zhao Y, Xiong Y, Wang X.	BMC Complement Med Ther	10.1186/s12906-020-03023-1	2020
	Butyrate modulates bacterial adherence on LS174T human colorectal cells by stimulating mucin secretion and MAPK signaling pathway.	Jung TH, Park JH, Jeon WM, Han KS.	Nutr Res Pract	10.4162/nrp.2015.9.4.343	2015
Metabolism	Probiotics (Bifidobacterium longum) Increase Bone Mass Density and Upregulate Sparc and Bmp-2 Genes in Rats with Bone Loss Resulting from Ovariectomy.	Parvaneh K, Ebrahimi M, Sabran MR, Karimi G, Hwei AN, Abdul-Majeed S, Ahmad Z, Ibrahim Z, Jamaluddin R.	Biomed Res Int	10.1155/2015/897639	2015
Pathogenicity	Effects of Pretreatment with Bifidobacterium bifidum Using 16S Ribosomal RNA Gene Sequencing in a Mouse Model of Acute Colitis Induced by Dextran Sulfate Sodium.	Weng YJ, Jiang DX, Liang J, Ye SC, Tan WK, Yu CY, Zhou Y.	Med Sci Monit	10.12659/msm.928478	2021
Metabolism	The gastrointestinal fate of limonin and its effect on gut microbiota in mice.	Gu M, Sun J, Qi C, Cai X, Goulette T, Song M, You X, Sela DA, Xiao H.	Food Funct	10.1039/c9fo01274e	2019
Pathogenicity	Butyrate Inhibits Osteoclast Activity In Vitro and Regulates Systemic Inflammation and Bone Healing in a Murine Osteotomy Model Compared to Antibiotic-Treated Mice.	Wallimann A, Magrath W, Pugliese B, Stocker N, Westermann P, Heider A, Gehweiler D, Zeiter S, Claesson MJ, Richards RG, Akdis CA, Hernandez CJ, O'Mahony L, Thompson K, Moriarty TF.	Mediators Inflamm	10.1155/2021/8817421	2021
	The Potential of Probiotics as a Therapy for Osteoporosis.	Collins FL, Rios-Arce ND, Schepper JD, Parameswaran N, McCabe LR.	Microbiol Spectr	10.1128/microbiolspec.bad-0015-2016	2017
	Quantification of Intestinal Lactobacillus Species in Children with Functional Constipation by Quantitative Real-Time PCR.	Jomehzadeh N, Javaherizadeh H, Amin M, Rashno M, Teimoori A.	Clin Exp Gastroenterol	10.2147/ceg.s250755	2020
Metabolism	Relevance of Bifidobacterium animalis subsp. lactis plasminogen binding activity in the human gastrointestinal microenvironment.	Candela M, Turroni S, Centanni M, Fiori J, Bergmann S, Hammerschmidt S, Brigidi P.	Appl Environ Microbiol	10.1128/aem.00413-11	2011
Genetics	Lactic acid bacteria and bifidobacteria deliberately introduced into the agro-food chain do not significantly increase the antimicrobial resistance gene pool.	Rozman V, Mohar Lorbeg P, Treven P, Accetto T, Golob M, Zdovc I, Bogovic Matijasic B.	Gut Microbes	10.1080/19490976.2022.2127438	2022
	Staphylococcus aureus in Foodborne Diseases and Alternative Intervention Strategies to Overcome Antibiotic Resistance by Using Natural Antimicrobials	Phan A, Mijar S, Harvey C, Biswas D.	Microorganisms		2025
	The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet.	Olson CA, Vuong HE, Yano JM, Liang QY, Nusbaum DJ, Hsiao EY.	Cell	10.1016/j.cell.2018.04.027	2018
Pathogenicity	In vivo selection to identify bacterial strains with enhanced ecological performance in synbiotic applications.	Krumbeck JA, Maldonado-Gomez MX, Martinez I, Frese SA, Burkey TE, Rasineni K, Ramer-Tait AE, Harris EN, Hutkins RW, Walter J.	Appl Environ Microbiol	10.1128/aem.03903-14	2015
Metabolism	Characterization of the serpin-encoding gene of Bifidobacterium breve 210B.	Turroni F, Foroni E, O'Connell Motherway M, Bottacini F, Giubellini V, Zomer A, Ferrarini A, Delledonne M, Zhang Z, van Sinderen D, Ventura M.	Appl Environ Microbiol	10.1128/aem.02938-09	2010
Metabolism	Advances in Probiotic Regulation of Bone and Mineral Metabolism.	McCabe LR, Parameswaran N.	Calcif Tissue Int	10.1007/s00223-018-0403-7	2018
	Large-Scale Molecular Evolutionary Analysis Uncovers a Variety of Polynucleotide Kinase Clp1 Family Proteins in the Three Domains of Life.	Saito M, Sato A, Nagata S, Tamaki S, Tomita M, Suzuki H, Kanai A.	Genome Biol Evol	10.1093/gbe/evz195	2019
	Intracellular Fusobacterium nucleatum infection attenuates antitumor immunity in esophageal squamous cell carcinoma.	Li Y, Xing S, Chen F, Li Q, Dou S, Huang Y, An J, Liu W, Zhang G.	Nat Commun	10.1038/s41467-023-40987-3	2023
	Upregulation of Intestinal Barrier Function in Mice with DSS-Induced Colitis by a Defined Bacterial Consortium Is Associated with Expansion of IL-17A Producing Gamma Delta T Cells.	Li M, Wang B, Sun X, Tang Y, Wei X, Ge B, Tang Y, Deng Y, He C, Yuan J, Li X.	Front Immunol	10.3389/fimmu.2017.00824	2017
Pathogenicity	Immunomodulatory properties of cell wall extract from Enterococcus faecalis CECT7121.	Sparo M, Delpech G, Batisttelli S, Basualdo JA.	Braz J Infect Dis	10.1016/j.bjid.2014.05.005	2014
Pathogenicity	Microbiota metabolites modulate the T helper 17 to regulatory T cell (Th17/Treg) imbalance promoting resilience to stress-induced anxiety- and depressive-like behaviors.	Westfall S, Caracci F, Zhao D, Wu QL, Frolinger T, Simon J, Pasinetti GM.	Brain Behav Immun	10.1016/j.bbi.2020.10.013	2021
Metabolism	A versatile and scalable strategy for glycoprofiling bifidobacterial consumption of human milk oligosaccharides.	Locascio RG, Ninonuevo MR, Kronewitter SR, Freeman SL, German JB, Lebrilla CB, Mills DA.	Microb Biotechnol	10.1111/j.1751-7915.2008.00072.x	2009
	Intestinal microbiota and probiotics in celiac disease.	de Sousa Moraes LF, Grzeskowiak LM, de Sales Teixeira TF, Gouveia Peluzio Mdo C.	Clin Microbiol Rev	10.1128/cmr.00106-13	2014
	Intestinal microbiota succession and immunomodulatory consequences after introduction of Lactobacillus reuteri I5007 in neonatal piglets.	Hou C, Liu H, Zhang J, Zhang S, Yang F, Zeng X, Thacker PA, Zhang G, Qiao S.	PLoS One	10.1371/journal.pone.0119505	2015
	Chronic Stress-Induced Depression and Anxiety Priming Modulated by Gut-Brain-Axis Immunity.	Westfall S, Caracci F, Estill M, Frolinger T, Shen L, Pasinetti GM.	Front Immunol	10.3389/fimmu.2021.670500	2021
Genetics	Technological advances in bifidobacterial molecular genetics: application to functional genomics and medical treatments.	Fukiya S, Hirayama Y, Sakanaka M, Kano Y, Yokota A.	Biosci Microbiota Food Health	10.12938/bmfh.31.15	2012
	Induction of bacterial antigen-specific colitis by a simplified human microbiota consortium in gnotobiotic interleukin-10-/- mice.	Eun CS, Mishima Y, Wohlgemuth S, Liu B, Bower M, Carroll IM, Sartor RB.	Infect Immun	10.1128/iai.01513-13	2014
Phylogeny	Comparative genomics of Bifidobacterium animalis subsp. lactis reveals a strict monophyletic bifidobacterial taxon.	Milani C, Duranti S, Lugli GA, Bottacini F, Strati F, Arioli S, Foroni E, Turroni F, van Sinderen D, Ventura M.	Appl Environ Microbiol	10.1128/aem.00984-13	2013
Phylogeny	Safety Assessment of a Nham Starter Culture Lactobacillus plantarum BCC9546 via Whole-genome Analysis.	Chokesajjawatee N, Santiyanont P, Chantarasakha K, Kocharin K, Thammarongtham C, Lertampaiporn S, Vorapreeda T, Srisuk T, Wongsurawat T, Jenjaroenpun P, Nookaew I, Visessanguan W.	Sci Rep	10.1038/s41598-020-66857-2	2020
Phylogeny	Molecular detection of bacterial contamination in gnotobiotic rodent units.	Packey CD, Shanahan MT, Manick S, Bower MA, Ellermann M, Tonkonogy SL, Carroll IM, Sartor RB.	Gut Microbes	10.4161/gmic.25824	2013
Metabolism	Consumption of human milk glycoconjugates by infant-associated bifidobacteria: mechanisms and implications.	Garrido D, Dallas DC, Mills DA.	Microbiology (Reading)	10.1099/mic.0.064113-0	2013
Biotechnology	A Human Gut Commensal Ferments Cranberry Carbohydrates To Produce Formate.	Ozcan E, Sun J, Rowley DC, Sela DA.	Appl Environ Microbiol	10.1128/aem.01097-17	2017
Metabolism	Diversity, ecology and intestinal function of bifidobacteria.	Bottacini F, Ventura M, van Sinderen D, O'Connell Motherway M.	Microb Cell Fact	10.1186/1475-2859-13-s1-s4	2014
Pathogenicity	Growth-Inhibiting and morphostructural effects of constituents identified in Asarum heterotropoides root on human intestinal bacteria.	Perumalsamy H, Jung MY, Hong SM, Ahn YJ.	BMC Complement Altern Med	10.1186/1472-6882-13-245	2013
Metabolism	A Review on Role of Microbiome in Obesity and Antiobesity Properties of Probiotic Supplements.	Sivamaruthi BS, Kesika P, Suganthy N, Chaiyasut C.	Biomed Res Int	10.1155/2019/3291367	2019
Enzymology	Improved selective and differential medium for isolation of Escherichia coli O157:H7.	Park SH, Ryu S, Kang DH.	J Clin Microbiol	10.1128/jcm.01359-10	2011
Pathogenicity	Study of the In Vitro Antagonistic Activity of Various Single-Strain and Multi-Strain Probiotics against Escherichia coli.	Fijan S, Sulc D, Steyer A.	Int J Environ Res Public Health	10.3390/ijerph15071539	2018
Enzymology	PCR detection and quantitation of predominant anaerobic bacteria in human and animal fecal samples.	Wang RF, Cao WW, Cerniglia CE.	Appl Environ Microbiol	10.1128/aem.62.4.1242-1247.1996	1996
Enzymology	Cloning and characterization of the bile salt hydrolase genes (bsh) from Bifidobacterium bifidum strains.	Kim GB, Miyamoto CM, Meighen EA, Lee BH.	Appl Environ Microbiol	10.1128/aem.70.9.5603-5612.2004	2004
Metabolism	Transforming berberine into its intestine-absorbable form by the gut microbiota.	Feng R, Shou JW, Zhao ZX, He CY, Ma C, Huang M, Fu J, Tan XS, Li XY, Wen BY, Chen X, Yang XY, Ren G, Lin Y, Chen Y, You XF, Wang Y, Jiang JD.	Sci Rep	10.1038/srep12155	2015
	Application of in vitro gut fermentation models to food components: A review.	Moon JS, Li L, Bang J, Han NS.	Food Sci Biotechnol	10.1007/s10068-016-0091-x	2016
Genetics	Comparative Genomics Reveals the Regulatory Complexity of Bifidobacterial Arabinose and Arabino-Oligosaccharide Utilization.	Arzamasov AA, van Sinderen D, Rodionov DA.	Front Microbiol	10.3389/fmicb.2018.00776	2018
Pathogenicity	In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria.	Tanaka K, Mikamo H, Nakao K, Ichiishi T, Goto T, Yamagishi Y, Watanabe K.	Antimicrob Agents Chemother	10.1128/aac.00595-08	2009
Metabolism	The ability of bifidobacteria to degrade arabinoxylan oligosaccharide constituents and derived oligosaccharides is strain dependent.	Riviere A, Moens F, Selak M, Maes D, Weckx S, De Vuyst L.	Appl Environ Microbiol	10.1128/aem.02853-13	2014
Pathogenicity	In vitro antimicrobial activity of razupenem (SMP-601, PTZ601) against anaerobic bacteria.	Tran CM, Tanaka K, Yamagishi Y, Goto T, Mikamo H, Watanabe K.	Antimicrob Agents Chemother	10.1128/aac.01038-10	2011
Enzymology	Detection of Bifidobacterium animalis subsp. lactis (Bb12) in the intestine after feeding of sows and their piglets.	Solano-Aguilar G, Dawson H, Restrepo M, Andrews K, Vinyard B, Urban JF.	Appl Environ Microbiol	10.1128/aem.00309-08	2008
	Relationship between total phenolic contents and biological properties of propolis from 20 different regions in South Korea.	Wang X, Sankarapandian K, Cheng Y, Woo SO, Kwon HW, Perumalsamy H, Ahn YJ.	BMC Complement Altern Med	10.1186/s12906-016-1043-y	2016
Enzymology	Quantification of bacterial groups within human fecal flora by oligonucleotide probe hybridization.	Sghir A, Gramet G, Suau A, Rochet V, Pochart P, Dore J.	Appl Environ Microbiol	10.1128/aem.66.5.2263-2266.2000	2000
Genetics	Development of the human infant intestinal microbiota.	Palmer C, Bik EM, DiGiulio DB, Relman DA, Brown PO.	PLoS Biol	10.1371/journal.pbio.0050177	2007
	Simultaneous immunofluorescent detection of coentrapped cells in gel beads.	Prioult G, Lacroix C, Turcotte C, Fliss I.	Appl Environ Microbiol	10.1128/aem.66.5.2216-2219.2000	2000
Enzymology	Species-specific oligonucleotide probes for five Bifidobacterium species detected in human intestinal microflora.	Yamamoto T, Morotomi M, Tanaka R.	Appl Environ Microbiol	10.1128/aem.58.12.4076-4079.1992	1992
	Commensal Obligate Anaerobic Bacteria and Health: Production, Storage, and Delivery Strategies.	Andrade JC, Almeida D, Domingos M, Seabra CL, Machado D, Freitas AC, Gomes AM.	Front Bioeng Biotechnol	10.3389/fbioe.2020.00550	2020
	Molecules produced by probiotics prevent enteric colibacillosis in pigs.	Nordeste R, Tessema A, Sharma S, Kovac Z, Wang C, Morales R, Griffiths MW.	BMC Vet Res	10.1186/s12917-017-1246-6	2017
Pathogenicity	Probiotic Bifidobacterium strains and galactooligosaccharides improve intestinal barrier function in obese adults but show no synergism when used together as synbiotics.	Krumbeck JA, Rasmussen HE, Hutkins RW, Clarke J, Shawron K, Keshavarzian A, Walter J.	Microbiome	10.1186/s40168-018-0494-4	2018
Metabolism	Sudan azo dyes and Para Red degradation by prevalent bacteria of the human gastrointestinal tract.	Xu H, Heinze TM, Paine DD, Cerniglia CE, Chen H.	Anaerobe	10.1016/j.anaerobe.2009.06.007	2010
Phylogeny	Identification and tracing of Bifidobacterium species by use of enterobacterial repetitive intergenic consensus sequences.	Ventura M, Meylan V, Zink R.	Appl Environ Microbiol	10.1128/aem.69.7.4296-4301.2003	2003
	The metabolic activity of gut microbiota in obese children is increased compared with normal-weight children and exhibits more exhaustive substrate utilization.	Payne AN, Chassard C, Zimmermann M, Muller P, Stinca S, Lacroix C.	Nutr Diabetes	10.1038/nutd.2011.8	2011
Phylogeny	Comparative study of bacterial groups within the human cecal and fecal microbiota.	Marteau P, Pochart P, Dore J, Bera-Maillet C, Bernalier A, Corthier G.	Appl Environ Microbiol	10.1128/aem.67.10.4939-4942.2001	2001
	A low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers.	Takahashi MK, Tan X, Dy AJ, Braff D, Akana RT, Furuta Y, Donghia N, Ananthakrishnan A, Collins JJ.	Nat Commun	10.1038/s41467-018-05864-4	2018
Pathogenicity	Strategies to Dissect Host-Microbial Immune Interactions That Determine Mucosal Homeostasis vs. Intestinal Inflammation in Gnotobiotic Mice.	Rogala AR, Oka A, Sartor RB.	Front Immunol	10.3389/fimmu.2020.00214	2020
	Probiotics and the Microbiome in Celiac Disease: A Randomised Controlled Trial.	Harnett J, Myers SP, Rolfe M.	Evid Based Complement Alternat Med	10.1155/2016/9048574	2016
Pathogenicity	In vitro antianaerobic activity of DX-619, a new des-fluoro(6) quinolone.	Tanaka K, Mikamo H, Nakao K, Watanabe K.	Antimicrob Agents Chemother	10.1128/aac.00639-06	2006
Metabolism	1H nuclear magnetic resonance spectroscopy-based studies of the metabolism of food-borne carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline by human intestinal microbiota.	Humblot C, Combourieu B, Vaisanen ML, Furet JP, Delort AM, Rabot S.	Appl Environ Microbiol	10.1128/aem.71.9.5116-5123.2005	2005
Enzymology	Characterization and heterologous expression of the oxalyl coenzyme A decarboxylase gene from Bifidobacterium lactis.	Federici F, Vitali B, Gotti R, Pasca MR, Gobbi S, Peck AB, Brigidi P.	Appl Environ Microbiol	10.1128/aem.70.9.5066-5073.2004	2004
Enzymology	Identification, detection, and enumeration of human bifidobacterium species by PCR targeting the transaldolase gene.	Requena T, Burton J, Matsuki T, Munro K, Simon MA, Tanaka R, Watanabe K, Tannock GW.	Appl Environ Microbiol	10.1128/aem.68.5.2420-2427.2002	2002
Phylogeny	Use of PCR and sodium dodecyl sulfate-polyacrylamide gel electrophoresis techniques for differentiation of Prevotella intermedia sensu stricto and Prevotella nigrescens.	Premaraj T, Kato N, Fukui K, Kato H, Watanabe K.	J Clin Microbiol	10.1128/jcm.37.4.1057-1061.1999	1999
	Influence of lactic acid bacteria on longevity of Caenorhabditis elegans and host defense against salmonella enterica serovar enteritidis.	Ikeda T, Yasui C, Hoshino K, Arikawa K, Nishikawa Y.	Appl Environ Microbiol	10.1128/aem.00704-07	2007
Pathogenicity	Novel riboswitch-binding flavin analog that protects mice against Clostridium difficile infection without inhibiting cecal flora.	Blount KF, Megyola C, Plummer M, Osterman D, O'Connell T, Aristoff P, Quinn C, Chrusciel RA, Poel TJ, Schostarez HJ, Stewart CA, Walker DP, Wuts PG, Breaker RR.	Antimicrob Agents Chemother	10.1128/aac.01282-15	2015
Enzymology	Fecal excretion of Bifidobacterium infantis 35624 and changes in fecal microbiota after eight weeks of oral supplementation with encapsulated probiotic.	Charbonneau D, Gibb RD, Quigley EM.	Gut Microbes	10.4161/gmic.24196	2013
Enzymology	Molecular analysis of the composition of the bifidobacterial and lactobacillus microflora of humans.	McCartney AL, Wenzhi W, Tannock GW.	Appl Environ Microbiol	10.1128/aem.62.12.4608-4613.1996	1996
Phylogeny	Development of cpn60-based real-time quantitative PCR assays for the detection of 14 Campylobacter species and application to screening of canine fecal samples.	Chaban B, Musil KM, Himsworth CG, Hill JE.	Appl Environ Microbiol	10.1128/aem.00101-09	2009
Enzymology	Alterations of the dominant faecal bacterial groups in patients with Crohn's disease of the colon.	Seksik P, Rigottier-Gois L, Gramet G, Sutren M, Pochart P, Marteau P, Jian R, Dore J.	Gut	10.1136/gut.52.2.237	2003
Enzymology	Bifidobacterial diversity in human feces detected by genus-specific PCR and denaturing gradient gel electrophoresis.	Satokari RM, Vaughan EE, Akkermans AD, Saarela M, de Vos WM.	Appl Environ Microbiol	10.1128/aem.67.2.504-513.2001	2001
	Molecular characterization of hsp20, encoding a small heat shock protein of bifidobacterium breve UCC2003.	Ventura M, Canchaya C, Zhang Z, Fitzgerald GF, van Sinderen D.	Appl Environ Microbiol	10.1128/aem.02496-06	2007
Pathogenicity	In vitro model of colonization resistance by the enteric microbiota: effects of antimicrobial agents used in food-producing animals.	Wagner RD, Johnson SJ, Cerniglia CE.	Antimicrob Agents Chemother	10.1128/aac.00852-07	2008
	The Bifidobacterium dentium Bd1 genome sequence reflects its genetic adaptation to the human oral cavity.	Ventura M, Turroni F, Zomer A, Foroni E, Giubellini V, Bottacini F, Canchaya C, Claesson MJ, He F, Mantzourani M, Mulas L, Ferrarini A, Gao B, Delledonne M, Henrissat B, Coutinho P, Oggioni M, Gupta RS, Zhang Z, Beighton D, Fitzgerald GF, O'Toole PW, van Sinderen D.	PLoS Genet	10.1371/journal.pgen.1000785	2009
Enzymology	Ruminococcin A, a new lantibiotic produced by a Ruminococcus gnavus strain isolated from human feces.	Dabard J, Bridonneau C, Phillipe C, Anglade P, Molle D, Nardi M, Ladire M, Girardin H, Marcille F, Gomez A, Fons M.	Appl Environ Microbiol	10.1128/aem.67.9.4111-4118.2001	2001
Phylogeny	Quantification of different Eubacterium spp. in human fecal samples with species-specific 16S rRNA-targeted oligonucleotide probes.	Schwiertz A, Le Blay G, Blaut M.	Appl Environ Microbiol	10.1128/aem.66.1.375-382.2000	2000
Pathogenicity	Streptococcus faecium-derived antibacterial substance antagonistic to Bifidobacteria.	Harasawa R, Suzuki K, Mitsuoka T.	Antimicrob Agents Chemother	10.1128/aac.18.1.58	1980
Enzymology	Structure of macroamphiphiles from several Bifidobacterium strains.	Iwasaki H, Araki Y, Ito E, Nagaoka M, Yokokura T.	J Bacteriol	10.1128/jb.172.2.845-852.1990	1990
Phylogeny	Analysis, characterization, and loci of the tuf genes in lactobacillus and bifidobacterium species and their direct application for species identification.	Ventura M, Canchaya C, Meylan V, Klaenhammer TR, Zink R.	Appl Environ Microbiol	10.1128/aem.69.11.6908-6922.2003	2003
Enzymology	Quantitative procedure for enumeration of bifidobacteria.	Resnick IG, Levin MA.	Appl Environ Microbiol	10.1128/aem.42.3.427-432.1981	1981
	Survival and enumeration of the fecal indicators Bifidobacterium adolescentis and Escherichia coli in a tropical rain forest watershed.	Carrillo M, Estrada E, Hazen TC.	Appl Environ Microbiol	10.1128/aem.50.2.468-476.1985	1985
	Expression of concern: Ingestion of Bifidobacterium longum subspecies infantis strain CCFM687 regulated emotional behavior and the central BDNF pathway in chronic stress-induced depressive mice through reshaping the gut microbiota.	Tian P, Zou R, Song L, Zhang X, Jiang B, Wang G, Lee YK, Zhao J, Zhang H, Chen W.	Food Funct	10.1039/d5fo90103k	2025
	Stimulation of Bifidobacterium longum viability and fermented milk quality by co-culture with Lactobacillus paracasei and inulin	Xiao M, Zang X, Tian F, Zhao J, Chen W, Zhai Q, Yu L.	Food Research International.		2025
	Plasmid-transformed Bifidobacterium longum 105A secreting beta-glucuronidase for prodrug conversion of SN-38 glucuronide.	Saisho A, Shimokawa M, Kubo R, Enomoto Y, Taniguchi S, Kobayashi H.	Protein Expr Purif	10.1016/j.pep.2025.106844	2025
	In silico study and optimization of bacteriocin family proteins from Bifidobacterium longum using response surface methodology.	Siavoshi M, Reza Fazeli M, Armand M, Dilmaghani A.	Prep Biochem Biotechnol	10.1080/10826068.2025.2560543	2025
	Effects of Bifidobacterium longum, Lactobacillus rhamnosus, and Lactobacillus reuteri on oral microbial balance and host cell functions: Implications for the prevention and management of oral diseases.	Zhu Z, Li X, Liu J, Chen L, Zhan Y, Wang L, Zhou L, Jiang D, Peng X, Jiang X.	Arch Oral Biol	10.1016/j.archoralbio.2025.106458	2025
	Bifidobacterium longum supplementation prevents intestinal inflammation and cognitive impairment in sleep-deprived mice by modulating clock gene expression.	Huang L, Li X, Guo M, Lu W, Zhao J, Xiao Y, Chen W.	Food Funct	10.1039/d5fo02921j	2025
	Human gut Bifidobacterium longum subsp. suillum is enriched in vitro by a pectic polysaccharide isolated from the flowers of Lilium lancifolium	Li M, Liu R, Wang T, Duo L, Chen G, Mao M, Sun Y, Li Y, Cai S, Zhou W, Lai H, Ding K.	Carbohydrate polymers.		2025
	Gut microbiome differences in Parkinson's disease patients in Central Kerala population.	Jacob AA, Rout S, Dash R, Venugopal G, Punde AR, John JK, Varghese SS, Cherupanakkal C, Mattethra GC, Ramadass B.	Neurodegener Dis Manag	10.1080/17582024.2025.2574204	2025
	Lactococcus lactis and Bifidobacterium longum attenuate Clostridioides difficile- or Clostridium symbiosum-induced colitis and depression/anxiety-like behavior in male mice.	Joo MK, Ma X, Shin JW, Shin YJ, Kim DH.	Microbes Infect	10.1016/j.micinf.2025.105560	2025
Metabolism	Bifidobacterium longum subsp. longum B-53 Alleviated Abnormalities of Glycolipid Metabolism and Oxidative Stress in T2DM Mice Through Regulating Gut Microbiota and GLP-1 Secretion.	Chen J, Zhang L, Cheng Z, Zhang Y, Li X, Zheng S, Zhang N, Li B, Liu F, Jiao Y.	J Agric Food Chem	10.1021/acs.jafc.5c07346	2025
	Dictyophora indusiata polysaccharide fractions promote the proliferation and metabolism of Bifidobacterium longum F2.	Wang L, Lin Y, Zeng Z, Zhang Z, Zheng B, Pan L, Zhang Y.	Food Funct	10.1039/d5fo02732b	2025
	Bacterial metabolite patterns of infants receiving multi-strain probiotics and risk of late-onset sepsis.	Waschina S, Pagel J, Seeger K, Pasderski E, Ruhlemann M, Froitzheim S, Kunzel S, Sommer F, Franzenburg S, Fortmann I, Sugihara F, Faust K, Marissen J, Demmert M, Baines JF, Gopel W, Herting E, Kaleta C, Rupp J, Hartel C.	Cell Rep	10.1016/j.celrep.2025.116431	2025
	Dominant Gut Commensals Enriched by Pectin with Low Esterification Degree Orchestrate the Amelioration of Acute Ulcerative Colitis.	Tan H, Chen M, Yao H, Li S, Nie S.	J Agric Food Chem	10.1021/acs.jafc.5c09097	2025
	Probiotic Intervention Mitigates Behavioural Effects of Maternal Morphine Exposure in Offspring.	Sadeghi-Adl M, Tarashi S, Zamani MS, Soltani H, Siadat SD, Zarrindast MR.	Int J Dev Neurosci	10.1002/jdn.70060	2025
	Probiotic Supplementation Enhances Functional Recovery and Modulates the Serum Metabolome in Mice.	Roberts JL, Kooima P, Kaiser J, Chi J, Gu H, Drissi H.	J Orthop Res	10.1002/jor.70073	2025
	Stimulation of Bifidobacterium longum viability and fermented milk quality by co-culture with Lactobacillus paracasei and inulin.	Xiao M, Zang X, Tian F, Zhao J, Chen W, Zhai Q, Yu L.	Food Res Int	10.1016/j.foodres.2025.117057	2025
	The impact of gut microbiota modulation on responses to immune checkpoint inhibitors in cancer.	Ni Z, Ye D.	Acta Microbiol Immunol Hung	10.1556/030.2025.02719	2025
Metabolism	Bifidobacterium longum TISTR 2893 Regulates Glycemic Homeostasis by Modulating the Hepatic Carbohydrate Metabolism in High-Fat Diet and Streptozotocin-Induced Type 2 Diabetic Rats.	Tasa K, Chonpathompikunlert P, Wongmanee N, Rojanaverawong W, Suttikul S, Kumlung T, Lekchaoum T, Hanchang W.	Probiotics Antimicrob Proteins	10.1007/s12602-025-10678-0	2025
	Parishin A reduces hepatic encephalopathy via gut microbiota increasing the activity of intestinal EAAT3 to reduce blood ammonia.	Lu JY, Zuo HT, Feng R, Chen YL, Ye ML, Xu H, Hu JC, Song JY, Zhao Y, Wang JY, Jin JY, Yuan TF, Wang WX, Zhao YF, Tu YM, Wei LY, Li MY, Cong B, Jiang JD, Wang Y.	Pharmacol Res	10.1016/j.phrs.2025.108030	2025
	The impact of Bifidobacterium longum CCFM1112 on chronic constipation: a randomised, double-blind, placebo-controlled study.	Liu W, Wang J, Xue Y, Li J, Huang Y, Zhu S, Wang L, Wang G, Chen W, Zhao J.	Benef Microbes	10.1163/18762891-bja00085	2025
	Elucidation of the pathway for Dictyophora indusiata polysaccharide-regulated differential acetic acid production by Bifidobacterium longum F2.	Zeng Z, Wang L, Zhang W, Lin Y, Wang B, Zhang Y, Zheng B, Pan L.	J Sci Food Agric	10.1002/jsfa.70027	2025
	In Vitro Amyloid Formation by a Bacteriocin From Bifidobacterium longum subsp. infantis.	Kumagai A, Mayanagi K, Hayashi S, Nakano S, Ito S, Fujinami D.	Proteins	10.1002/prot.70002	2025
	Probiotics Ameliorate Aging-Related Cognitive Impairments and Pathological Changes through Alleviating Telomere Attrition and Enhancing Mitochondrial Function in Senescence-Accelerated Mouse Prone 8 Mice.	Zhou S, Shan S, Li R, Wang X, Xiong J, Cheng G.	J Agric Food Chem	10.1021/acs.jafc.5c09572	2025
Pathogenicity	Investigation of the Mitigating Mechanism of Bifidobacterium longum 300 in d-Galactose-Induced Cognitive Impairment in Mice.	Zhang X, Ma X, Zhang J, Nie H, Mu G, Wu X.	J Agric Food Chem	10.1021/acs.jafc.5c01742	2025
	Unraveling the causal relationship between gut microbiota and chronic hepatitis B: A large-scale mediation Mendelian randomization analysis.	Yuan T, Chen J, Yang J, Pu J, Lu Y, Zheng H, Xu J.	Microb Pathog	10.1016/j.micpath.2025.108179	2025
Pathogenicity	Synbiotics as Modulators of Developing Brain for Reproductive Development Via Estrogen Receptors in Male Coturnix Coturnix Japonica.	Khan A, Sikdar M, Kango N, Srivastava R.	Neurochem Res	10.1007/s11064-025-04528-2	2025
	BCL-2 Multi-Strain Probiotics for Immunomodulation In Vitro and In Vivo Alleviation of Atopic Dermatitis.	Sung M, Sim S, Lim A, Moon JS, Jeon J, Heo K, Kwak W, Park MS, Kwak J, Park E, Yoon S.	Microorganisms	10.3390/microorganisms13081950	2025
	L-theanine mediates Hsf1 protection of intestinal mucosal barrier through Bifidobacterium to alleviate heat stress.	Liang H, Yang Y, Yao K, Lin L, Wang B, Liu S, Gong Z, Xiao W.	J Nutr Biochem	10.1016/j.jnutbio.2025.110177	2025
	Engineered Bifidobacterium Strains Colonization at Tumor Sites: A Novel Approach to the Delivery of Cancer Treatments.	Amonkar R, Uy AA, Ramirez P, Patel H, Jeong JJ, Shoyele NO, Vaghela V, Lakshmikuttyamma A.	Cancers (Basel)	10.3390/cancers17152487	2025
	Cold-set gels from fresh duck egg white for probiotic delivery and application in mayonnaise.	Liu YC, Chen YP, Chen HN, Shiu JS, Wang SY.	Poult Sci	10.1016/j.psj.2025.106089	2025
	Bifidobacterium longum BL300 alleviates DSS-induced Colitis by promoting IgA-mediated Gut Microbiota homeostasis.	Jin H, Wang H, Feng X, Ma X, Zhai Z, Hao Y.	Food Funct	10.1039/d5fo00992h	2025
	Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 administration to Long-Evans rats has interactive effects with sex and diet on anxiety-related feeding behaviors and specific endocrine outcomes.	Myles EM, O'Leary ME, Romkey ID, Hamm SI, Dauphinee L, Piano A, Bronner S, Perrot TS.	Physiol Behav	10.1016/j.physbeh.2025.115030	2025
	Strain specific effects of probiotic supplementation on serum amino acid profiles in Alzheimer's disease: a randomized, double blind, placebo controlled trial.	Jouni N, Akhgarjand C, Vahabi Z, Shab-Bidar S, Khalifeh H, Djafarian K.	Sci Rep	10.1038/s41598-025-15355-4	2025
	Microbial modulators of the mind: probiotic interventions in hippocampal neurogenesis and cognitive flexibility.	Zhao J, Liu H, Badehnoosh B.	Antonie Van Leeuwenhoek	10.1007/s10482-025-02162-0	2025
	Maternal gut microbiota transmission and early-life colonization patterns influence infant CMPA risk.	Zhang L, Ge X, Shen P, Zhou Y, Hu S, Xu H.	Microbiol Spectr	10.1128/spectrum.01162-25	2025
	Targeted probiotic therapy in irritable bowel syndrome: a clinical evaluation on Clostridium butyricum CBM588 and Bifidobacterium longum W11.	Bertuccioli A, Sisti D, Lazzerini N, Palazzi CM, Zonzini GB, Ragazzini M, Belli A.	Front Med (Lausanne)	10.3389/fmed.2025.1604319	2025
	Machine Learning Identifies a Distinct Microbiota Signature in Immune Checkpoint Inhibitor Colitis Compared with Inflammatory Bowel Disease.	Barberio B, Patuzzi I, Bertin L, Facchin S, De Ruvo M, Bonazzi E, De Barba C, Dal Maso A, Frega S, Simionati B, Sattin E, Buda A, Zingone F, Burra P, Dei Tos AP, Pasello G, Bonanno L, Savarino EV.	Oncologist	10.1093/oncolo/oyaf376	2025
Pathogenicity	Probiotics Decrease C-Reactive Protein Levels in Depression Depending on Metabolic Syndrome Presence or Antidepressant Treatment - Secondary Results of a Randomized Clinical Trial.	Kotelnicka OG, Wysokinski A, Gajewska A, Czarnecka-Chrebelska K, Kopacz K, Skowronska A, Pikus E, Brzezianska-Lasota E, Strzelecki D.	Curr Neuropharmacol	10.2174/011570159x371175251002220658	2025
	Microencapsulation of Lactobacillus acidophilus LA-832 and Bifidobacterium longum BL-101 by using sodium alginate and chitosan to improve the survival in simulated gastrointestinal conditions.	Ullah FS, Saeed M, Shabbir MA, Israr B.	J Food Sci Technol	10.1007/s13197-025-06345-5	2025
Pathogenicity	Probiotics restore GABAergic neurons and attenuate postnatal seizures in periventricular leukomalacia.	Chen JS, Tu MJ, Chang YM, Tu YF, Chiang CW.	Nutr Neurosci	10.1080/1028415x.2025.2574964	2025
Metabolism	Prebiotic Administration to CKD Patients Modifies Their Microbiome and Metabolism.	Raj DS, Gao B, Sohn MB, Brydges C, Srivastava A, Rabb H, Cheung AK, Fiehn O, Kendrick C, Gassman JJ, Tariq A, Isakova T, Fried LF, Wolf M, Raphael KL, Middleton JP, Abdalla Y, Pilot Studies in CKD Consortium.	J Ren Nutr	10.1053/j.jrn.2025.10.015	2025
	Levan-like exopolysaccharide EPS-SOM8 produced by Bacillus subtilis SOM8 isolated from sesame oil meal as potential prebiotic and synbiotic formulations for altering human gut microbiome.	Zhao Z, Chua LW, Feng S, Kang X, Wong SH, Loo SCJ.	Int J Biol Macromol	10.1016/j.ijbiomac.2025.147391	2025
Metabolism	The role of probiotics in modulating RANKL in osteoporosis: A systematic review of animal interventional studies and RCTs.	Hamedi-Kalajahi F, Alizadeh M, Kheirouri S.	Bone	10.1016/j.bone.2025.117622	2025
	Human gut Bifidobacterium longum subsp. suillum is enriched in vitro by a pectic polysaccharide isolated from the flowers of Lilium lancifolium.	Li M, Liu R, Wang T, Duo L, Chen G, Mao M, Sun Y, Li Y, Cai S, Zhou W, Lai H, Ding K.	Carbohydr Polym	10.1016/j.carbpol.2025.123772	2025
	The psychobiotic revolution: comprehending the optimistic role of gut microbiota on gut-brain axis during neurological and Gastrointestinal (GI) disorders.	Mohiuddin M, Asghar T, Hameed H, Din AM, Siddique A, Younas S, Mohi Ud Din M, Ara R.	World J Microbiol Biotechnol	10.1007/s11274-025-04632-z	2025
	Comparative effectiveness and safety of probiotics with psychotropic potential in mental health benefits in irritable bowel syndrome: a systematic review and network meta-analysis.	Rokkas T, Ekmektzoglou K, Tsanou E, Bricca L, Menni AE, Golfakis P, Kotzampassi K.	Eur J Gastroenterol Hepatol	10.1097/meg.0000000000003062	2025
	Assembly of the infant gut microbiome and resistome are linked to bacterial strains in mother's milk.	Ferretti P, Allert M, Johnson KE, Rossi M, Heisel T, Gonia S, Knights D, Fields DA, Albert FW, Demerath EW, Gale CA, Blekhman R.	Nat Commun	10.1038/s41467-025-66497-y	2025
	Restoring Balance: Probiotic Modulation of Microbiota, Metabolism, and Inflammation in SSRI-Induced Dysbiosis Using the SHIME^® Model.	de Oliveira MT, de Oliveira FL, Salgaco MK, Mesa V, Sartoratto A, Duailibi K, Raimundo BVB, Ramos WS, Sivieri K.	Pharmaceuticals (Basel)	10.3390/ph18081132	2025
	Bifidobacterium animalis subsp. lactis BLa80 for preventing allergic, respiratory, and gastrointestinal diseases in young children in China: a randomized double-blind placebo-controlled trial.	Chen K, Zhang X, Zeng K, Zhong J, Jin S, Nie Y, Yang P, He N, Chen H, Cao Y, Fu Y, Fang Z, Jiang W, Liu C.	Clin Exp Pediatr	10.3345/cep.2025.01256	2025
	Gut microbial diversity is preserved through localised chemo-immunotherapy delivery in a KPC mouse model of pancreatic cancer.	Minaei E, Joyce P, Wade SJ, Brownlee C, Penney C, Ranson M, Aghmesheh M, Sluyter R, Vine-Perrow KL.	J Control Release	10.1016/j.jconrel.2025.114143	2025
Pathogenicity	Bifidobacterium longum Ameliorates Intestinal Inflammation and Metabolic Biomarkers in Mice Fed a High-Fat Diet with Gliadin by Indoleacrylic Acid.	Wang N, Pei Z, Wang H, Zhao J, Lu W.	Probiotics Antimicrob Proteins	10.1007/s12602-025-10486-6	2025
	The organic acid metabolites of Bifidobacterium longum subsp. iuvenis alleviate ultraviolet irradiation-induced photoaging.	Dou S, Pan W, Pan X, Li Y, Mao J, Cheng J, Yan X, Wang T, Zhou X, Zhang SY, Zhang G.	Microbiol Res	10.1016/j.micres.2025.128100	2025
	Identification of a Differential Microbiological Signature of Extended-Spectrum ß-Lactamases Producing Escherichia Carriers in Spanish Community Children.	Cardinali-Benigni M, Khannous-Lleiffe O, Saus E, Carmena D, McConnell MJ, Gabaldon T, Lopez-Siles M.	Microbiologyopen	10.1002/mbo3.70077	2025
	Vinegar-processed frankincense ameliorates ulcerative colitis by targeting BSH-active bacteria preference-mediated GDCA hydrolysis.	Lu W, Liu Z, Song Z, Wang C, Yu Z, Peng S, Tian Z, Lyu A, Ning Z.	J Ethnopharmacol	10.1016/j.jep.2025.119845	2025
	Development of a bio-functional fermented soy beverage supplemented with microbial exopolysaccharides and its effect on the human gut microbiome in vitro.	Bisson G, Comuzzi C, FitzGerald JA, Mukherjee A, Renoldi N, Innocente N, Beresford T, Mathur H, Cotter PD, Marino M.	Food Funct	10.1039/d5fo01288k	2025
	Microbiome-mediated colonization resistance to carbapenem-resistant Klebsiella pneumoniae in ICU patients.	Yang J, Zhou Y, Du A, Zhang Z, Wang B, Tian Y, Liu H, Cai L, Pang F, Li Y, Du C, Wu X, Yan C, Wu W, Jiang M, Shen K, Zhang C, Feng Y, Kang Y, Shen B, Zong Z.	NPJ Biofilms Microbiomes	10.1038/s41522-025-00791-x	2025
	A phase II clinical trial of Bifidobacterium longum subsp. longum BL21 for preventing acute radiation enteritis among pelvic radiotherapy patients.	Yang Y, Gu X, Liu C, Zou L, Xie L, Liu Y, Zhao P, Tian Y, Cai S.	Front Nutr	10.3389/fnut.2025.1626169	2025
	Modulation of gut propionate and intestinal mucosal protection by Bifidobacterium longum: Mitigating methotrexate side effects without compromising the efficacy of psoriasis therapy.	Mao M, Yuan Y, Li R, Kuang Y, Lu Y, Zhu W, Chen W.	Int Immunopharmacol	10.1016/j.intimp.2025.114196	2025
	Bifidobacterium longum subsp. longum XZ01 delays the progression of colon cancer in mice through the interaction between the microbial spatial distribution and tumour immunity.	Chen Y, Wu J, Cai K, Xiao X, Chen Y, Zhang X, Deng S, Pei C, Chen Y, Xie Z, Li P, Liao Q.	Int Immunopharmacol	10.1016/j.intimp.2025.114283	2025
	Impact of prebiotics and postbiotics in the management of constipation: Analysis of their differentiated modulation of intestinal microbiota.	Culqui Levano DR, Rodriguez Sanz P, Palacios Sanchez R, Saldana Miranda MY, Santa Cruz Lopez CY, Mateus Rodriguez JA.	Clin Nutr ESPEN	10.1016/j.clnesp.2025.08.003	2025
	Bifidobacterium longum subsp. longum relieves loperamide hydrochloride-induced constipation in mice by enhancing bile acid dissociation.	Zhang C, Wang L, Liu X, Wang G, Zhao J, Chen W.	Food Funct	10.1039/d4fo04660a	2025
Pathogenicity	Construction of a simplified co-culture system using MDCK cells as surrogate intestinal epithelium with intestinal anaerobic bacterial mixtures.	Umehara Y, Aoyagi H.	J Biosci Bioeng	10.1016/j.jbiosc.2025.06.010	2025
	Analyzing potential of next-generation probiotics in cancer management.	Naz SS, Zafar S.	Mol Biol Rep	10.1007/s11033-025-10737-3	2025
Pathogenicity	Probiotic secretomes attenuate inflammation and disrupted antioxidant status induced by polychlorinated biphenyls in human intestinal T84 epithelial cells.	Lu F, MacPherson CW, Iskandar MM, Kubow S.	Free Radic Biol Med	10.1016/j.freeradbiomed.2025.07.008	2025
	Bifidobacterium longum can degrade the urinary N -glycoprotein Uromodulin.	Al Khoury E, Gourdine JP.	MicroPubl Biol	10.17912/micropub.biology.001724	2025
	The intervention of B. longum metabolites in Fnevs' carcinogenic capacity: A potential double-edged sword.	Xu J, Wu X, Yang L, Xu X.	Exp Cell Res	10.1016/j.yexcr.2025.114407	2025
	Alleviation of Helicobacter pylori- or aspirin-induced gastritis and neuroinflammation in mice by Lactococcus lactis and Bifidobacterium longum.	Shin JW, Shin YJ, Lee DY, Kim DH.	Lett Appl Microbiol	10.1093/lambio/ovae128	2024
	Bacteria enable tolerance to bile salt exposure in an immune-competent human intestinal model.	Li Y, Wang CM, Zhao P, Fernez MT, Carrier RL.	Gut Microbes	10.1080/19490976.2025.2514144	2025
	Studies of methylated CpG ODN from Bifidobacterium longum subsp. infantis in a murine model: Implications for treatment of human allergic disease.	Li D, Sorkhabi S, Cruz I, Foley PL, Bellanti JA.	Allergy Asthma Proc	10.2500/aap.2025.46.240100	2025
	Multi-omics characterization of gut microbiota and fecal and plasma metabolites in patients with primary Sjögren's syndrome.	Liu Y, Wang Q, Zhang Y, Duo R, Bian X, Tian J, Hao J, Zheng J, Shen H.	Clin Rheumatol	10.1007/s10067-025-07642-2	2025
	Increased survival rate of selected probiotics under environmental stresses through encapsulation in alpha-glucan-coated porous starch granules.	Kwon TE, Kim DM, Seo DH, Hamaker BR, Yoo SH.	Int J Biol Macromol	10.1016/j.ijbiomac.2025.140754	2025
	Bifid Triple Viable Capsules alleviate constipation by modulating gut microbiota and maintaining the integrity of the intestinal epithelial barrier.	Sun D, Yu J, Zhan Y, Cheng X, Zhang J, Li Y, Li Q, Xiong Y, Liu W.	Benef Microbes	10.1163/18762891-bja00076	2025
	Dose-response studies of methylated and nonmethylated CpG ODNs from Bifidobacterium longum subsp. infantis for optimizing Treg cell stimulation.	Li D, Cruz I, Sorkhabi S, Foley PL, Wagner J, Bellanti JA.	Allergy Asthma Proc	10.2500/aap.2025.46.250001	2025
	Pullulan-spermine enhance the tolerance of probiotics and immune stimulation of macrophages.	Meng Z, He Q, Mu L, Feng J, Zhang F, Wu J, Zhou L, Hu Q, Tang X, Li Y.	Int J Biol Macromol	10.1016/j.ijbiomac.2024.138417	2025
	Bifidobacterium longum Metabolite Indole-3-Carboxaldehyde Blocks HDAC3 and Inhibits Macrophage NLRP3 Inflammasome Activation in Intestinal Ischemia/Reperfusion Injury.	Miao Y, Wang M, Sun H, Zhang Y, Zhou W, Yang W, Duan L, Niu L, Li Z, Chen J, Li Y, Fan A, Xie Q, Wei S, Bai H, Wang C, Chen Q, Wang X, Li Y, Liu J, Han Y, Fan D, Hong L.	Inflammation	10.1007/s10753-024-02211-2	2025
	The gut core microbial species Bifidobacterium longum: Colonization, mechanisms, and health benefits.	Xiao Y, Huang L, Zhao J, Chen W, Lu W.	Microbiol Res	10.1016/j.micres.2024.127966	2025
	Mitigating effect of Bifidobacterium longum CCFM1077 on nonylphenol toxicity: An integrative in vitro and in vivo analysis.	Ye Z, Yu L, Lu D, Zhang Q, Narbad A, Chen W, Zhai Q, Tian F.	J Hazard Mater	10.1016/j.jhazmat.2024.136401	2024
	Screening of potential probiotic bifidobacteria from intestinal tract and its application in fermented milk.	Li Y, Fan Q, Dong H, Chang S, Liu W.	J Dairy Sci	10.3168/jds.2024-25960	2025
	Comparing the survivability of various probiotic strains through the pelleting process	Jacobs RW, Ayala D, Dunmire K, Gordon ME.	J Equine Vet Sci		2025
	Effects of a live versus heat-inactivated probiotic Bifidobacterium spp in preterm infants: a randomised clinical trial.	Athalye-Jape G, Esvaran M, Patole S, Nathan EA, Doherty DA, Sim E, Chandrasekaran L, Kok C, Schuster S, Conway P.	Arch Dis Child Fetal Neonatal Ed	10.1136/archdischild-2023-326667	2025
Pathogenicity	Effects of supplementation with two probiotic strains (Lactobacillus helveticus and Bifidobacterium longum) on hormonal status, oxidative stress, and clinical symptoms in women with polycystic ovary syndrome: a randomized clinical trial.	Shirani M, Bagherniya M, Sadeghi O, Ghasemi Tehrani H, Eskandari MH, Sharma M, Askari G.	Nutr J	10.1186/s12937-025-01240-3	2025
	Treatment with the Bifidobacterium longum Strain DSM 32947 Increases Bone Mineral Density in Female Mice.	Ohlsson C, Hagg D, Horkeby K, Nilsson KH, Lawenius L, Wu J, Koskela A, Tuukkanen J, Grahnemo L, Lundberg LE, Roos S, Sjogren K.	Calcif Tissue Int	10.1007/s00223-025-01429-y	2025
	Investigating the bidirectional interactions between senotherapeutic agents and human gut microbiota.	Sangfuang N, Xie Y, McCoubrey LE, Taub M, Favaron A, Mai Y, Gaisford S, Basit AW.	Eur J Pharm Sci	10.1016/j.ejps.2025.107098	2025
	Investigation of associations between the neonatal gut microbiota and severe viral lower respiratory tract infections in the first 2 years of life: a birth cohort study with metagenomics.	Garcia-Maurino C, Shao Y, Miltz A, Lawley TD, Rodger A, Field N.	Lancet Microbe	10.1016/j.lanmic.2024.101072	2025
	Insights into the modulatory effects of host-gut microbial xanthine co-metabolism on high-fat diet-fed mice.	Chen WB, Hu GA, Dong BC, Sun HY, Lu DZ, Ru MY, Yu YL, Wang H, Wei B.	Biochem Pharmacol	10.1016/j.bcp.2024.116596	2024
	Production of 2-O-alpha-d-glucopyranosyl-l-ascorbic acid using sucrose phosphorylase by semi-rational design.	Shen Y, Guo J, Xia Y, Wei L, Lin X, Liu Y, Chen Y, Bao Y, Yang H, Chen X.	Int J Biol Macromol	10.1016/j.ijbiomac.2024.138213	2025
Pathogenicity	Comparative evaluation of dulaglutide alone vs. dulaglutide combined with probiotics on cardiovascular risk factors in T2DM.	Tian J, Yang Y, Yu Z, Gao Y, Zong X, Wu Q, Su H, Cao W, Xu D.	Hormones (Athens)	10.1007/s42000-025-00649-z	2025
	Oral administration of Bifidobacterium longum and Bifidobacterium infantis ameliorates cefcapene pivoxil-induced attenuation of anti-programmed cell death protein-1 antibody action in mice.	Funayama E, Hosonuma M, Tajima K, Isobe J, Baba Y, Murayama M, Narikawa Y, Toyoda H, Tsurui T, Maruyama Y, Sasaki A, Amari Y, Yamazaki Y, Nakashima R, Uchiyama J, Nakano R, Shida M, Sasaki A, Udaka Y, Oguchi T, Sambe T, Kobayashi S, Tsuji M, Kiuchi Y, Kim YG, Wada S, Tsunoda T, Akiyama M, Nobe K, Kuramasu A, Yoshimura K.	Biomed Pharmacother	10.1016/j.biopha.2024.117749	2025
	Sugarcane bagasse derived xylooligosaccharides produced by an arabinofuranosidase/xylobiohydrolase from Bifidobacterium longum in synergism with xylanases	Capetti CCdM, Ontanon O, Navas LE, Campos E, Simister R, Dowle A, Liberato MV, Pellegrini VdOA, Gomez LD, Polikarpov I.	Carbohydrate polymers.		2024
	Enhancement of the flavor and functional characteristics of cod protein isolate using an enzyme-microbe system.	Yan ZF, Chen JY, Yang J, Yuan S, Qiao XY, Xu B, Su LQ.	Food Funct	10.1039/d4fo02272f	2024
	Preventive impact of probiotic supplements on heart injury and inflammatory indices in a rat model of myocardial infarction: histopathological and gene expression evaluation.	Bonab SF, Tahmasebi S, Ghafouri-Fard S, Eslami S.	APMIS	10.1111/apm.13479	2025
	Gut-resident regulatory T cells (GTregs) play a pivotal role in maintaining bone health under postmenopausal osteoporotic conditions.	Bhardwaj A, Sapra L, Madan D, Ahuja V, Sharma HP, Velpandian T, Mishra PK, Srivastava RK.	J Leukoc Biol	10.1093/jleuko/qiaf008	2025
	Preventive and therapeutic impact of probiotic supplementation on behavior and inflammatory responses in the PTZ-induced chemical kindling in rats.	Tahmasebi S, Bonab SF, Ghafouri-Fard S, Eslami S.	Psychopharmacology (Berl)	10.1007/s00213-025-06760-8	2025
	Exploring the clinical value of probiotics in the perioperative management of colorectal cancer: Meta-analysis with trial sequential analysis.	Zhang Y, Hu J, Xu Q, Yu Y, Yan H, Shao W, Zhang F.	Oncol Lett	10.3892/ol.2025.15261	2025
	Probiotic modulation of central and peripheral sensitization in a migraine model via the gut-brain-trigeminal axis.	Suthivanich P, Vongseenin S, Auvichayapat V, Supronsinchai W, Tumwasorn S, Chayanupatkul M, Bongsebandhu-Phubhakdi S.	Sci Rep	10.1038/s41598-025-24928-2	2025
	Harnessing the Power of Probiotics: Boosting Immunity and Safeguarding against Various Diseases and Infections.	Singh A, Mazumder A, Das S, Kanda A, Tyagi PK, Chaitanya MVNL.	Recent Adv Antiinfect Drug Discov	10.2174/0127724344308638240530065552	2025
	Antimicrobial activity and sensory acceptability of probiotic-strained (Torba) yogurt with medicinal and aromatic plants	Bayram OY, Kinik O, Buyukkileci C.	S Afr J Bot		2024
Cultivation	Optimization of Medium Composition for High Cell Density Culture of Bifidobacterium longum HSBL001 Using Response Surface Methodology.	Cheng H, Liu J, Mei L, Liu W, Yang F, Ma X, Zhang Y, Xie Y, Zhang Y, Xiong Y.	Microbiologyopen	10.1002/mbo3.70027	2025
	Effect of Ultrahigh-Pressure on the Physicochemical Properties and Biological Activities of Dietary Fiber From Litchi Pomace.	Zuo YH, Xu YJ, Wu JJ, Wen J, Zou B, Li L, Peng J, Cheng LN, Bu ZB, Yu YS, Hu TG.	J Food Sci	10.1111/1750-3841.70289	2025
	Anaerobic probiotics-in situ Se nanoradiosensitizers selectively anchor to tumor with immuno-regulations for robust cancer radio-immunotherapy.	Yu Y, Wang Y, Zhang J, Bu Q, Jiang D, Jiang Y, Xu L, Ju Z, Chen T.	Biomaterials	10.1016/j.biomaterials.2025.123117	2025
	Use of Macrogol to Accelerate Feeding Advancement in Extremely Preterm Infants.	Faust KB, Lupatsii M, Romer F, Graspeuntner S, Waschina S, Zimmermann S, Humberg A, Fortmann MI, Hanke K, Bockenholt K, Dirks J, Silwedel C, Rupp J, Herting E, Gopel W, Hartel C.	Neonatology	10.1159/000543050	2025
	Effects of Bifidobacterium longum 35624 in Children and Adolescents with Irritable Bowel Syndrome.	Cruchet Munoz S, Verbeke Palma S, Lera Marques L, Espinosa Pizarro MN, Malig Mechasqui J, Sorensen K.	Nutrients	10.3390/nu16121967	2024
	Are Bifidobacterium Species Key Players in the Progression of Type 1 Diabetes? A Systematic Review.	Vergoz V, Jeong D, Hamilton-Williams EE.	Endocrinol Diabetes Metab	10.1002/edm2.70120	2025
	Probiotic supplementation for optimizing athletic performance: current evidence and future perspectives for microbiome-based strategies.	Teglas T, Radak Z.	Front Nutr	10.3389/fnut.2025.1572687	2025
	The Role of Infant Gut Microbiota Modulation by Perinatal Maternal Probiotic Intervention in Atopic Eczema Risk Reduction.	Puisto R, Gomez-Gallego C, Collado MC, Turta O, Isolauri E, Rautava S.	Neonatology	10.1159/000540075	2025
	Bifidobacterium longum S3 alleviates loperamide-induced constipation by modulating intestinal acetic acid and stearic acid levels in mice.	Zhang T, Lu H, Cheng T, Wang L, Wang G, Zhang H, Chen W.	Food Funct	10.1039/d4fo00695j	2024
	Bifidobacterium longum GL001 alleviates rat intestinal ischemia-reperfusion injury by modulating gut microbiota composition and intestinal tissue metabolism.	Tang J, Zhao M, Miao X, Chen H, Zhao B, Wang Y, Guo Y, Wang T, Cheng X, Ruan H, Zhang J.	Food Funct	10.1039/d3fo03669c	2024
	Synbiotic modulation of adult gut microbiome by 2'-fucosyllactose and Bifidobacterium longum subsp. infantis EFEL8008.	Lee DH, Seong H, Kim SA, Han NS.	Microbiome Res Rep	10.20517/mrr.2025.35	2025
Genetics	Metagenomics Investigation on Baby Diaper Area Microbiome and Its Association with Skin pH and Dermatitis in the Diapered Area.	Hu P, Carr AN, Parlov M, Swift D, Tiesman JP, Ramji N, Schoch JJ, Teufel AG.	Microorganisms	10.3390/microorganisms13112632	2025
	Biotransformation analysis of daidzin in vitro based on fecal bacteria and probiotics.	Wang Y, Li Z, Wu D, Wang Z, Wang S, Jiang Q, Gong X, Xia C.	J Pharm Biomed Anal	10.1016/j.jpba.2024.116623	2025
	Inhibitory Potential of Bifidobacterium longum FB1-1 Cell-Free Supernatant against Carbapenem-Resistant Klebsiella pneumoniae Drug Resistance Spread.	Wang J, Fan DC, Wang RS, Chang Y, Ji XM, Li XY, Zhang Y, Liu JM, Wang S, Wang J.	Microorganisms	10.3390/microorganisms12061203	2024
	Bifidobacterium longum-Derived Extracellular Vesicles Prevent Hepatocellular Carcinoma by Modulating the TGF-beta1/Smad Signaling in Mice.	Li B, Chi X, Huang Y, Wang W, Liu Z.	Front Biosci (Landmark Ed)	10.31083/j.fbl2907241	2024
Genetics	Joint Bacterial Traces in the Gut and Oral Cavity of Obesity Patients Provide Evidence for Saliva as a Rich Microbial Biomarker Source.	Rehner J, Gund M, Becker SL, Hannig M, Rupf S, Schattenberg JM, Keller A, The Imagine Consortium, Molano LG, Keller V.	Nutrients	10.3390/nu17223527	2025
Metabolism	Molecular insights into FucR transcription factor to control the metabolism of _L-fucose in Bifidobacterium longum subsp. infantis.	Yang X, Zhang J, Zhu J, Yang R, Tong Y.	Microbiol Res	10.1016/j.micres.2024.127709	2024
	Assessing the effects of probiotic supplementation, single strain versus mixed strains, on femoral mineral density and osteoblastic gene mRNA expression in rats.	Parvaneh M, Jamaluddin R, Ebrahimi M, Karimi G, Sabran MR.	J Bone Miner Metab	10.1007/s00774-024-01512-8	2024
	Postcholecystectomy Gut Microbiome Changes and the Clinical Impact: A Systematic Review With Narrative Synthesis.	Ang TL, Koo SH, Ang D, Tan CK, Wang LM, Wong SH, Chow PKH.	J Gastroenterol Hepatol	10.1111/jgh.16846	2025
	Impact of two human milk oligosaccharides and lactose on the faecal microbiome of infants with probable cow's milk allergy.	Van den Abbeele P, Heine RG, Van de Vliet M, Favre L, Tytgat HLP, Sprenger N, Deyaert S, Baudot A, Nutten S.	Benef Microbes	10.1163/18762891-bja00048	2024
	Bifidobacterium longum P77 and Lactiplantibacillus plantarum P72 and Their Mix-Live or Heat-Treated-Mitigate Sleeplessness and Depression in Mice: Involvement of Serotonergic and GABAergic Systems.	Baek JS, Ma X, Park HS, Lee DY, Kim DH.	Cells	10.3390/cells14191547	2025
	An In Vitro Evaluation of the Effect of Bifidobacterium longum L556 on Microbiota Composition and Metabolic Properties in Patients with Coronary Heart Disease (CHD).	Yang L, Wu Y, Zhao X, Liang T, Li L, Yang J, Jiang T, Zhang T, Zhang J, Zhong H, Xie X, Wu Q.	Probiotics Antimicrob Proteins	10.1007/s12602-024-10267-7	2025
	Synergistic effects of Bifidobacterium longum subsp. infantis B8762 and milk-derived osteopontin on male reproductive health in mice.	Zhao C, Gao G, Zhang T, Li N, Zhao Y, Lu Z, Zhang Y, Sun Z.	J Sci Food Agric	10.1002/jsfa.70121	2025
	FMT reduces systemic inflammatory response in severe acute pancreatitis by increasing the abundance of intestinal Bifidobacteria and fecal bacteria.	Mao Y, Huang Y, Zhang W, Liang H, Liu F, Luo Q, Xu C, Qin Y, Liu J, Tang S, Liu H, Ge X.	Biomol Biomed	10.17305/bb.2024.11445	2025
	A postbiotic exopolysaccharide synergizes with Lactobacillus acidophilus to reduce intestinal inflammation in a mouse model of colitis.	Ma C, Zheng X, Zhang Q, Renaud SJ, Yu H, Xu Y, Chen Y, Gong J, Cai Y, Hong Y, Li H, Liao Q, Guo Y, Kang L, Xie Z.	Int J Biol Macromol	10.1016/j.ijbiomac.2024.138931	2025
	Highly conserved bifidobacteria in the human gut: Bifidobacterium longum subsp. longum as a potential modulator of elderly innate immunity.	Longhi G, Lugli GA, Bianchi MG, Rizzo SM, Tarracchini C, Mancabelli L, Vergna LM, Alessandri G, Fontana F, Taurino G, Chiu M, Milani C, van Sinderen D, Bussolati O, Ventura M, Turroni F.	Benef Microbes	10.1163/18762891-bja00013	2024
Pathogenicity	A Symbiotic Meal Containing Extruded Sorghum and Probiotic (Bifidobacterium longum) Ameliorated Intestinal Health Markers in Individuals with Chronic Kidney Disease: A Secondary Analysis of a Subsample from a Previous Randomized and Controlled Clinical Trial.	Lucio HG, Lopes RCSO, Gomes MJC, da Silva A, Grancieri M, Della Lucia CM, Queiroz VAV, da Silva BP, Martino HSD.	Nutrients	10.3390/nu16121852	2024
Metabolism	Bifidobacterium longum subsp. longum dipro-O: a potential therapeutic agent for ameliorating metabolic disorders in high-fat diet-induced obesity mouse model.	Xu N, Luo J, Chen W, Xiang W, Zhai Y, Jiang W, Wu J, Hao Y, Chen M, Yu Q.	Front Endocrinol (Lausanne)	10.3389/fendo.2025.1519058	2025
	Gut microbiota influences lung cancer risk through circulating cytokines-Insights from a Mendelian randomization study.	Shen W, Hou R, Zhang J, Liu C, Zhang C, Liu X.	Medicine (Baltimore)	10.1097/md.0000000000044897	2025
	Sugarcane bagasse derived xylooligosaccharides produced by an arabinofuranosidase/xylobiohydrolase from Bifidobacterium longum in synergism with xylanases.	Capetti CCM, Ontanon O, Navas LE, Campos E, Simister R, Dowle A, Liberato MV, Pellegrini VOA, Gomez LD, Polikarpov I.	Carbohydr Polym	10.1016/j.carbpol.2024.122248	2024
	Impact of synbiotics on disease activity in systemic lupus erythematosus: Results from a randomized clinical trial.	Mirfeizi Z, Mahmoudi M, Jokar MH, Sahebari M, Noori E, Mehrad-Majd H, Barati M, Faridzadeh A.	J Food Sci	10.1111/1750-3841.17460	2024
	Process Development for the Enzymatic Gram-Scale Production of the Unnatural Nucleotide Sugar UDP-6-Azido-GalNAc.	Frohnmeyer H, Verkade JMM, Spiertz M, Rentsch A, Hoffmann N, Sobota M, Schwede F, Tjeerdsma P, Elling L.	ChemSusChem	10.1002/cssc.202400311	2024
	Perioperative Oral Immunonutrient Regulation of Intestinal Barrier and Gut Microbiota in Patients with Gastric Cancer, a Randomized Controlled Clinical Trial.	Zheng Z, Liu G, Wang Y, Li J, Zhang C, Zhang Y, Ye X, Kang W.	Biomedicines	10.3390/biomedicines13092163	2025
	Versatile inulin/trans-ferulic acid/silk sericin nanoparticles-nourished probiotic complex with prolonged intestinal retention for synergistic therapy of inflammatory bowel disease.	Zhang Y, Zhang X, Lv L, Gao S, Li X, Wang R, Wang P, Shi F, She J, Wang Y.	Carbohydr Polym	10.1016/j.carbpol.2024.123063	2025
	Exopolysaccharides Produced by Bifidobacterium longum subsp. longum YS108R Ameliorates DSS-Induced Ulcerative Colitis in Mice by Improving the Gut Barrier and Regulating the Gut Microbiota.	Li H, Li H, Stanton C, Ross RP, Zhao J, Chen W, Yang B.	J Agric Food Chem	10.1021/acs.jafc.3c06421	2024
	Probiotics may be useful for drug-induced liver dysfunction in patients with depression - A secondary analysis of a randomized clinical trial.	Gawlik-Kotelnicka O, Burzynski J, Rogalski J, Skowronska A, Strzelecki D.	Clin Nutr ESPEN	10.1016/j.clnesp.2024.07.1024	2024
	The Role of Plasma Metabolites in Mediating the Effect of Gut Microbiota on Obstructive Sleep Apnea: A Two-Step, Two-Sample Mendelian Randomization Study.	Wang X, Zhao R, Guo J, Yang K, Xu B.	Nat Sci Sleep	10.2147/nss.s527778	2025
	A Randomized Controlled Trial Evaluating the Effects of a Probiotic Containing Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 on Gastrointestinal Symptoms and Metabolomic Profiles in Female Dancers.	Wiacek J, Skonieczna-Zydecka K, Loniewski I, Styburski D, Kaczmarczyk M, Karolkiewicz J.	Int J Mol Sci	10.3390/ijms26125823	2025
	Effect of Bifidobacterium longum subsp. infantis YLGB-1496 on common diseases in pediatrics: a randomized, blinded, placebo-controlled trial.	Zhang X, Chen K, Lan H, Chen H, Chen H, Yang P, He N, Hung W, Zeng Z, Liu C.	Front Nutr	10.3389/fnut.2025.1585504	2025
	Assessment of the efficacy of a feed additive consisting of Bifidobacterium longum CNCM I-5642 (PP102I) for dogs (Nestlé Enterprises S.A.).	EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Villa RE, Azimonti G, Bonos E, Christensen H, Durjava M, Dusemund B, Gehring R, Glandorf B, Kouba M, Lopez-Alonso M, Marcon F, Nebbia C, Pechova A, Prieto-Maradona M, Rohe I, Theodoridou K, Martelli G, Anguita M, Innocenti ML, Ortuno J.	EFSA J	10.2903/j.efsa.2025.9254	2025
	A Probiotic Bacterium with Activity against the Most Frequent Bacteria and Viruses Causing Pediatric Diarrhea: Bifidobacterium longum subsp. infantis CECT 7210 (B. infantis IM1^®).	Moreno-Munoz JA, Ojeda JD, Lopez JJ.	Microorganisms	10.3390/microorganisms12061183	2024
	Sourdough bread enriched with exopolysaccharides and gazpacho by-products modulates in vitro the microbiota dysbiosis.	Nieto JA, Roses C, Viadel B, Gallego E, Romo-Hualde A, Milagro FI, Barcelo A, Virto R, Saldana G, Luengo E.	Int J Biol Macromol	10.1016/j.ijbiomac.2024.132906	2024
	Antibiotic Resistance in Bifidobacterium animalis subsp. lactis and Bifidobacterium longum: Definition of Sensitivity/Resistance Profiles at the Species Level.	Terlizzi M, Speranza B, Sinigaglia M, Corbo MR, Bevilacqua A.	Microorganisms	10.3390/microorganisms13071647	2025
	Structure dependent fermentation kinetics of dietary carrot rhamnogalacturonan-I in an in vitro gut model	Desai K, Van den Abbeele P, Duysburgh C, Albers R, Wennekes T, Schols HA, Mercenier A.	Food hydrocolloids.		2024
Pathogenicity	The Gut Microbiome and Its Impact on Mood and Decision-Making: A Mechanistic and Therapeutic Review.	Diotaiuti P, Misiti F, Marotta G, Falese L, Calabro GE, Mancone S.	Nutrients	10.3390/nu17213350	2025
	Survival and safety evaluation of Bifidobacterium longum subsp. longum ZS-8 in healthy adults, determined using PMAxx-qPCR and amplicon sequencing.	Liu F, Dong B, Wang Z, Lin D, Xu H, Ke B, Kang W, Jin Y, Huang X, Lu H, Zhao L, Qian Y, Cai L, Xu L, Xu ZZ.	Microbiol Spectr	10.1128/spectrum.02861-24	2025
	Restoring Balance: Probiotic Modulation of Microbiota, Metabolism, and Inflammation in SSRI-Induced Dysbiosis Using the SHIME® Model	de Oliveira M, de Oliveira F, Salgaco M, Mesa V, Sartoratto A, Duailibi K, Raimundo B, Ramos W, Sivieri K.	Pharmaceuticals (Basel)		2025
	Efficacy of probiotics regimens for Helicobacter pylori eradication: A systematic review, pairwise, and network meta-analysis of randomized controlled trials.	Tanashat M, Abuelazm M, Abouzid M, Al-Ajlouni YA, Ramadan A, Alsalah S, Sharaf A, Ayman D, Elharti H, Zhana S, Altobaishat O, Abdelazeem B, Jaber F.	Clin Nutr ESPEN	10.1016/j.clnesp.2024.11.016	2025
	Analysis of microbiotas between traumatic and ulcerative wound: insights into challenges of current wounds managements.	Chen C, Wang J, Li Y, Fan Z, Dai Y.	Front Cell Infect Microbiol	10.3389/fcimb.2025.1622552	2025
Metabolism	Effects of defatted rice bran-fortified bread on gut microbiome, cardiovascular risk, gut discomfort, wellbeing and gut physiology in healthy adults with low dietary fibre intake.	Ng HM, Maggo J, Wall CL, Bayer SB, Mullaney JA, Cabrera D, Fraser K, Cooney JM, Gunther CS, McNabb WC, Foster M, Frampton C, Gearry RB, Roy NC.	Clin Nutr ESPEN	10.1016/j.clnesp.2025.03.045	2025
	Protective effects of Bifidobacterium longum subsp. longum BL21 against cyclophosphamide-induced reproductive dysfunction in zebrafish.	Dong Y, Zhou J, Tian H, Gai Z, Zou K, Wei Q, Han M.	Sci Rep	10.1038/s41598-025-97721-w	2025
	Data-Driven Monitoring of Probiotic Fermentation in Fruit Juices Using Near-Infrared Spectroscopy and Aquaphotomics: An Innovative Approach to Food Valorization.	Regatieri L, Vitalis F, Bujna E, Nguyen QD, Kovacs Z.	Foods	10.3390/foods14071274	2025
	In vitro fermentation characteristics and interaction of neutral and acidic polysaccharides from Lycii fructus on human gut microbiota	Liang X, Liu M, Yao A, Cui W, Wei Y, Guo S, Duan J, Kang H, Zhou X, Su S, Jin H, Zhang F, Duan J.	Food hydrocolloids.		2024
Transcriptome	Association of alterations in transcriptomics and intestinal immune responses with Bifidobacterium longum BAA2573 in improving dextran sulfate sodium-induced colitis.	Hao W, Gu L, Zhou R, Huang C, Wang X, Liu Y, Lin Q.	BMC Gastroenterol	10.1186/s12876-025-04116-2	2025
	Lacticaseibacillus casei- and Bifidobacterium breve-fermented red pitaya promotes beneficial microbial proliferation in the colon.	Cao L, Wan M, Xian Z, Zhou Y, Dong L, Huang F, Su D.	Food Funct	10.1039/d4fo02352h	2024
	Varying Bifidobacterium species in the maternal-infant gut microbiota correlate with distinct early neurodevelopmental outcomes.	Liu C, Lu Q, Xi Q, Xiao S, Du J, Qin R, Wang J, Xu B, Han X, Zhou K, Tao S, Lv H, Jiang Y, Jiang T, Ye K, Jin G, Ma H, Xia Y, Shen H, Liu X, Lin Y, Hu Z.	J Genet Genomics	10.1016/j.jgg.2025.01.015	2025
	Improvement of 3D printing age-friendly brown rice food on rough texture, swallowability, and in vitro digestibility using fermentation properties of different probiotics.	Huang J, Zhang M, Mujumdar AS, Wang Y, Li C.	Food Chem	10.1016/j.foodchem.2024.140701	2024
	Evaluation of a probiotic blend on psychosocial health and biomarkers of inflammatory, immune and stress response in adults with subthreshold depression: a double-blind, randomised, placebo-controlled trial.	Moschonis G, Sarapis K, Resciniti S, Hall R, Yim K, Tonkovic M, Fitzgerald C, Anixiadis F, Vinh A, Dinh QN, Cronin RA, Hale MW, Wright BJ, Pane M, Tuck CJ, Biesiekierski JR.	Br J Nutr	10.1017/s0007114524001703	2024
	Therapeutic Potential of Cynara scolymus Extract and Bifidobacterium longum in Alleviating Diabetes-Induced Male Reproductive Dysfunction.	Bozorgpoursavadjani H, Keyghobadi H, Moghadam D, Zare R, Dehghani F, Jamhiri I, Koohpeyma F, Dastghaib S.	Int J Endocrinol	10.1155/ije/5884930	2025
	Effects of 2'-fucosyllactose on the viability of starter cultures and Bifidobacterium strains of human origin in yogurt during refrigerated storage.	Xie Z, Kim C, Miller MJ, Jin YS.	J Food Sci	10.1111/1750-3841.16996	2024
	Complementary immunoregulatory effects of Bifidobacterium longum 1714^TM associated exopolysaccharide and tryptophan metabolism.	Groeger D, Yao L, Collins F, Larsen IS, Tan HT, Healy S, Ambrogi V, Tykwinska K, Schmidt M, Golletz P, Kiely B, Clarke G, Dinan TG, Murphy EF, O'Mahony L.	Curr Res Microb Sci	10.1016/j.crmicr.2025.100481	2025
	Application of probiotic therapy in nonalcoholic fatty liver disease: mediating mechanism and future perspective.	Luo XY, Huang WB, Lu CH, Gu W, Feng ZX, Shen S, Chen MZ, Zheng SS, Yang Z.	Front Cell Infect Microbiol	10.3389/fcimb.2025.1638372	2025
	Probiotics in IBD: Evidence and Perspectives on Patient Health and Disease Management.	Hijova E.	Int J Mol Sci	10.3390/ijms26189065	2025
	Blood metabolites reflect the effect of gut microbiota on differentiated thyroid cancer: a Mendelian randomization analysis.	Zhang H, Li Y, Li L.	BMC Cancer	10.1186/s12885-025-13598-y	2025
	Differences in physicochemical, rheological, and prebiotic properties of inulin isolated from five botanical sources and their potential applications.	Lin X, Zhang X, Xu B.	Food Res Int	10.1016/j.foodres.2024.114048	2024
	Analysis of the safety and probiotic properties of Bifidobacterium longum B2-01 by complete genome sequencing combined with corresponding phenotypes	Peng YY, Zhong SY, Xu XL, Liu DM.	Lebensm Wiss Technol		2023
	Physicochemical Characterization and Immunomodulatory Activity of Polyelectrolyte Multilayer Coatings Incorporating an Exopolysaccharide from Bifidobacterium longum.	Bagnol R, Siverino C, Barnier V, O'Mahony L, Grijpma DW, Eglin D, Moriarty TF.	Biomacromolecules	10.1021/acs.biomac.3c00516	2023
	Bifidobacterium longum subsp. infantis regulates Th1/Th2 balance through the JAK-STAT pathway in growing mice.	Ding M, Li B, Chen H, Ross RP, Stanton C, Jiang S, Zhao J, Chen W, Yang B.	Microbiome Res Rep	10.20517/mrr.2023.64	2024
Pathogenicity	Synbiotics containing sea buckthorn polysaccharides ameliorate DSS-induced colitis in mice via regulating Th17/Treg homeostasis through intestinal microbiota and their production of BA metabolites and SCFAs.	Yuan M, Chang L, Gao P, Li J, Lu X, Hua M, Li X, Liu X, Lan Y.	Int J Biol Macromol	10.1016/j.ijbiomac.2024.133794	2024
	Beneficial effect of consuming milk containing only A2 beta-casein on gut microbiota: A single-center, randomized, double-blind, cross-over study.	Song CH, Kim N, Choi Y, Kim S, Kim KS, Park MH, Lee SH, Lee DH.	PLoS One	10.1371/journal.pone.0323016	2025
	Impact of Dietary Probiotics on the Immune and Reproductive Physiology of Pubertal Male Japanese Quail (Coturnix coturnix japonica) Administered at the Onset of Pre-Puberty.	Khan A, Kango N, Srivastava R.	Probiotics Antimicrob Proteins	10.1007/s12602-023-10209-9	2025
Pathogenicity	Zinc-Enriched Bifidobacterium longum subsp. longum CCFM1195 Alleviates Cutibacterium acnes-Induced Skin Lesions in Mice by Mitigating Inflammatory Responses and Oxidative Stress.	Gu X, Wang B, Zhang T, Zhang Q, Mao B, Tang X, Zhao J, Cui S.	Nutrients	10.3390/nu17111803	2025
	Gut microbiome composition and functionality impact the responsiveness to a dairy-based product containing galacto-oligosaccharides for improving sleep quality in adults.	Kortman GAM, Hester ER, Schaafsma A, Mulder J, Mallee L, Nauta A.	Benef Microbes	10.1163/18762891-bja00017	2024
	Multi-omics technology reveals the changes in gut microbiota to stimulate aromatic amino acid metabolism in children with allergic rhinitis and constipation.	Wang C, Liu H, Li X, Kong W, Wu H, Huang C.	Front Allergy	10.3389/falgy.2025.1562832	2025
	Gut microbiota therapy for chronic kidney disease.	Liu C, Wang J, Lei L, Li L, Yuan X.	Front Immunol	10.3389/fimmu.2025.1660226	2025
	Active Inclusion Bodies in the Multienzymatic Synthesis of UDP-N-acetylglucosamine.	Koszagova R, Palencarova K, Nahalka J.	Int J Mol Sci	10.3390/ijms26199679	2025
	Methylated CpG ODNs from Bifidobacterium longum subsp. infantis Modulate Treg Induction and Suppress Allergic Response in a Murine Model.	Li D, Cruz I, Peltak SN, Foley PL, Bellanti JA.	Int J Mol Sci	10.3390/ijms26146755	2025
	Bifidobacterium longum subsp. infantis B6MNI Alleviates Collagen-Induced Arthritis in Rats via Regulating 5-HIAA and Pim-1/JAK/STAT3 Inflammation Pathways.	Li B, Ding M, Chen C, Zhao J, Shi G, Ross P, Stanton C, Chen W, Yang B.	J Agric Food Chem	10.1021/acs.jafc.3c05371	2023
	Exploring the Interplay Between Gut Microbiota and the Melatonergic Pathway in Hormone Receptor-Positive Breast Cancer.	Laborda-Illanes A, Boutriq S, Aranega-Martin L, Castellano-Castillo D, Sanchez-Alcoholado L, Plaza-Andrades I, Peralta-Linero J, Alba E, Fernandez-Garcia JC, Gonzalez-Gonzalez A, Queipo-Ortuno MI.	Int J Mol Sci	10.3390/ijms26146801	2025
Pathogenicity	Integrated multi-omics reveals different host crosstalk of atopic dermatitis-enriched Bifidobacterium longum Strains.	Seong HJ, Park YM, Kim BS, Yoo HJ, Kim T, Yoon SM, Kim JH, Lee SY, Lee YK, Lee DW, Nam MH, Hong SJ.	NPJ Biofilms Microbiomes	10.1038/s41522-025-00714-w	2025
	Indole Derivatives Biosynthesis in Bifidobacterium longum subsp. infantis and the Tryptophan Substrate Availability.	Zhang SM, Wu HC, Hung JH, Huang SL.	Microb Biotechnol	10.1111/1751-7915.70167	2025
	[Long-term probiotic administration for irritable bowel syndrome: a legal need].	Solovyeva OI, Nekrasova AS, Topalova IG, Ponomarenko VA, Tsurtsumiia DB, Ilyashevich IG.	Ter Arkh	10.26442/00403660.2023.08.202378	2023
	Microbiota-A Rescuing Modulator in Children Struggling with Functional Constipation.	Tomsa NA, Melit LE, Popescu T, Najjar K, Vasiesiu AM, Pop AV, Borka-Balas R.	Microorganisms	10.3390/microorganisms13071504	2025
	Non-Animal Hyaluronic Acid and Probiotics Enhance Skin Health via the Gut-Skin Axis: An In Vitro Study on Bioavailability and Cellular Impact.	Galla R, Mule S, Ferrari S, Molinari C, Uberti F.	Int J Mol Sci	10.3390/ijms26030897	2025
Genetics	Machine learning integrates region-specific microbial signatures to distinguish geographically adjacent populations within a province.	Luo L, Chen B, Zeng S, Li Y, Chen X, Zhang J, Guo X, Li S, Ruan L, Zhu S, Gao C, Zhang C, Li T.	Front Microbiol	10.3389/fmicb.2025.1586195	2025
	Gut bacteria-driven homovanillic acid alleviates depression by modulating synaptic integrity.	Zhao M, Ren Z, Zhao A, Tang Y, Kuang J, Li M, Chen T, Wang S, Wang J, Zhang H, Wang J, Zhang T, Zeng J, Liu X, Xie G, Liu P, Sun N, Bao T, Nie T, Lin J, Liu P, Zheng Y, Zheng X, Liu T, Jia W.	Cell Metab	10.1016/j.cmet.2024.03.010	2024
	Adaptation to tolerate high doses of arabinoxylan is associated with fecal levels of Bifidobacterium longum.	Deehan EC, Zhang Z, Nguyen NK, Perez-Munoz ME, Cole J, Riva A, Berry D, Prado CM, Walter J.	Gut Microbes	10.1080/19490976.2024.2363021	2024
	Optimizing chronic kidney disease management: The potential of a multi-strain probiotic formulation.	Chafekar D.	World J Nephrol	10.5527/wjn.v14.i1.101515	2025
	Multi-omics analysis of the biofilm forming mechanism of Bifidobacterium longum	Zhang T, Liu Z, Zhao J, Zhang H, Chen W, Li H, Lu W, Xiao Y, Zhou X.	Lebensm Wiss Technol		2023
	Bifidobacterium longum subsp. longum BL21 ameliorates alcoholic liver disease in mice through enhancement of the hepatic antioxidant capacity and modulation of the gut microbiota.	Dong Y, Wu Z, Gai Z, Han M.	J Appl Microbiol	10.1093/jambio/lxad251	2023
	The effectiveness of probiotics as an adjunct therapy in patients under mechanical ventilation: an umbrella systematic review and meta-analysis.	Anvarifard P, Anbari M, Ghalichi F, Ghoreishi Z, Zarezadeh M.	Food Funct	10.1039/d3fo04653b	2024
	Investigating the potential of yacon (Smallanthus sonchifolius) juice in the development of organic apple-based snacks.	Braschi G, Njieukam JA, Gottardi D, Genovese J, Tylewicz U, Patrignani F, Rocculi P.	Heliyon	10.1016/j.heliyon.2024.e32342	2024
	Bifidobacterium longum subsp. infantis CCFM1426 enhances the anti-colitic effect of vitamin A via retinoic acid restoration and gut microbiota modulation in ulcerative colitis mice.	Yu X, Huang L, Wang Y, Li L, Lu W, Zhang Z, Wang H.	Front Nutr	10.3389/fnut.2025.1644649	2025
	Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 Supplementation: An Exploratory, Randomized, Placebo-Controlled Trial of Endocannabinoid and Inflammatory Responses in Female Dancers.	Wiacek J, Skonieczna-Zydecka K, Loniewski I, Deli CK, Fatouros IG, Jamurtas AZ, Moszczynska D, Karolkiewicz J.	Microorganisms	10.3390/microorganisms13061284	2025
	Up-regulation of sortase-dependent pili in Bifidobacterium longum BBMN68 in response to bile stress enhances its adhesion to HT-29 cells.	Zhai Z, Xiong Y, Gu Y, Lei Y, An H, Yi H, Zhao L, Ren F, Hao Y.	Int J Biol Macromol	10.1016/j.ijbiomac.2023.127527	2024
	Supplementation with the Probiotic Strains Bifidobacterium longum and Lactiplantibacillus rhamnosus Alleviates Glucose Intolerance by Restoring the IL-22 Response and Pancreatic Beta Cell Dysfunction in Type 2 Diabetic Mice.	Kim WJ, Ryu R, Doo EH, Choi Y, Kim K, Kim BK, Kim H, Kim M, Huh CS.	Probiotics Antimicrob Proteins	10.1007/s12602-023-10156-5	2025
	Proteomic analyses of Bacteroides ovatus and Bifidobacterium longum in xylan bidirectional culture shows sugar cross-feeding interactions	Vega-Sagardia M, Delgado J, Ruiz-Moyano S, Garrido D.	Food Research International.		2023
	Gut microbiota of sub-Saharan Africa infants exposed to antiretroviral therapy: Scoping review.	Mudhluli TE, Mashingaidze-Mano R, Chitsike I, Manasa J, Hall LJ, Gomo E, Zhou DT.	Afr J Prim Health Care Fam Med	10.4102/phcfm.v17i1.4939	2025
Phylogeny	Longitudinal changes in bifidobacterial population during the first two years of life.	An R, Fontana F, Van Daele E, Ventura M, Vlieger A, van Elburg RM, Knol J, Milani C, Belzer C.	Benef Microbes	10.1163/18762891-bja00012	2024
	Impact of supplementing Limosilactobacillus fermentum MN-LF23 on the eradication of Helicobacter pylori with 14-day standard quadruple therapy: a randomized, double-blind, placebo-controlled trial.	Zhao Y, Niu X, Zhang Y, Zhao L, Zhang L, He J, Zhang Q, Mao Y, Wang F, Zhao X, Wang R.	Nutr J	10.1186/s12937-025-01124-6	2025
Genetics	Limitations of MALDI-TOF MS in identifying anaerobic bacteremia: challenges in polymicrobial infections and the role of whole-genome sequencing.	Hosoda T, Suzuki M, Matsuno T, Matsui K, Ohyama K, Doi Y.	Microbiol Spectr	10.1128/spectrum.01014-25	2025
	Oral administration of Bifidobacterium longum WHH2270 ameliorates type 2 diabetes in rats.	Gao K, Ren X, Chen C, Fan Q, Li Y, Wang H, Chen S.	J Food Sci	10.1111/1750-3841.16727	2023
Pathogenicity	Modulatory impact of Bifidobacterium longum subsp. longum BL21 on the gut-brain-ovary axis in polycystic ovary syndrome: insights into metabolic regulation, inflammation mitigation, and neuroprotection.	Dong Y, Yang S, Zhang S, Zhao Y, Li X, Han M, Gai Z, Zou K.	mSphere	10.1128/msphere.00887-24	2025
	Isolation, identification, and in vitro probiotic characterization of forty novel Bifidobacterium strains from neonatal feces in Erzurum province, Türkiye	Guler MA, Cetin B, Albayrak B, Meral-Aktas H, Tekgunduz KS, Kara M, Islek A.	Journal of the Science of Food and Agriculture.		2024
	Persistent reduction of Bifidobacterium longum in the infant gut microbiome in the first year of age following intrapartum penicillin prophylaxis for maternal GBS colonization.	Teuscher JL, Lupatsii M, Graspeuntner S, Jonassen S, Bringewatt A, Herting E, Stichtenoth G, Bossung V, Rupp J, Hartel C, Demmert M.	Front Immunol	10.3389/fimmu.2025.1540979	2025
	Clinical effects of Bifidobacterium Longum Subsp. Infantis YLGB-1496 on children with respiratory symptoms.	Li P, Mageswary U, Ali A, Taib F, Koo TH, Yusof A, Jiang H, Lan H, Hung W, Liong MT, Zhang Y.	Front Nutr	10.3389/fnut.2025.1537610	2025
	Probiotics as an adjunct in the treatment of canine atopic dermatitis: a systematic review and meta-analysis of in vivo studies in dogs.	Pacheco RCF, Lins LF, DE Brito LP, DE Andrade Calaca PR, Porto ALF, Cavalcanti MTH.	J Vet Med Sci	10.1292/jvms.24-0471	2025
	Efficacy of Lactobacillus spp. Interventions to Modulate Mood Symptoms: A Scoping Review of Clinical Trials	Fernandez-Rodriguez D, Bravo M, Pizarro M, Vergara-Barra P, Hormazabal M, Leonario-Rodriguez M.	Int J Mol Sci		2025
	Gut microbiota and metabolic signatures of anxiety in ulcerative colitis: a cross-sectional study.	Ping Y, Zhao X, Lv L, Meng W, Meng Y, Ruan G, Cheng Y, Xiao Z, Tian Y, Chen M, Chen L, Yi A, Tang Z, Li N, Chen D, Wei Y.	Therap Adv Gastroenterol	10.1177/17562848251393419	2025
	Gut microbiome differences after vaginal birth in relation to rupture of membranes at term: a prospective longitudinal cohort study of twins.	Cuerva MJ, Bartha I, Escribano E, Chueca G, de Aguado MP, Espinosa-Martos I, Esteban S, De La Calle M, Jimenez E, Bartha JL.	Eur J Pediatr	10.1007/s00431-025-06336-w	2025
	Bifidobacterium longum promotes postoperative liver function recovery in patients with hepatocellular carcinoma.	Yu J, Zhu P, Shi L, Gao N, Li Y, Shu C, Xu Y, Yu Y, He J, Guo D, Zhang X, Wang X, Shao S, Dong W, Wang Y, Zhang W, Zhang W, Chen WH, Chen X, Liu Z, Yang X, Zhang B.	Cell Host Microbe	10.1016/j.chom.2023.11.011	2024
	Effects of probiotics, prebiotics, and synbiotics on gut microbiota in older adults: a systematic review and meta-analysis of randomized controlled trials.	Zhuang K, Luo H, Zeng M, Chan SCL, Gong M, Wang Y.	Nutr J	10.1186/s12937-025-01218-1	2025
	[Improving the technology for obtaining an ingredient with probiotic properties using a new complex proteolytic enzyme preparation].	Kuksova EV, Kostyleva EV, Sereda AS, Toloknova AA, Fursova EA, Volkova GS.	Vopr Pitan	10.33029/0042-8833-2024-93-5-142-152	2024
	Konjac Oligosaccharides Alleviated Ovariectomy-Induced Bone Loss through Gut Microbiota Modulation and Treg/Th17 Regulation.	Ai T, Shang L, Li B, Li J, Qin R.	J Agric Food Chem	10.1021/acs.jafc.4c00281	2024
	Effects of Bifidobacterium on metabolic parameters in overweight or obesity adults: a systematic review and meta-analysis.	Huang J, Cheng H.	Front Microbiol	10.3389/fmicb.2025.1633434	2025
	Bifidobacterium infantis and Bifidobacterium breve Improve Symptomatology and Neuronal Damage in Neurodegenerative Disease: A Systematic Review.	Reiriz M, Beltran-Velasco AI, Echeverry-Alzate V, Martinez-Miguel E, Gomez-Senent S, Uceda S, Clemente-Suarez VJ.	Nutrients	10.3390/nu17030391	2025
Genetics	Multikingdom characterization of gut microbiota in patients with rheumatoid arthritis and rheumatoid arthritis-associated interstitial lung disease.	Xing Y, Liu Y, Sha S, Zhang Y, Dou Y, Liu C, Xu M, Zhao L, Wang J, Wang Y, Ma X, Yan Q, Kong X.	J Med Virol	10.1002/jmv.29781	2024
Pathogenicity	Meta-analytical insight on probiotic metabolites and inflammatory markers in diabetes.	Xie Y, Zheng Y, Jiang F, Cai X.	Front Cell Infect Microbiol	10.3389/fcimb.2025.1677671	2025
	Elucidation of the Tissue Distribution and Host Immunostimulatory Activity of Exogenously Administered Probiotic-Derived Extracellular Vesicles for Immunoadjuvant.	Morishita M, Kida M, Motomura T, Tsukamoto R, Atari M, Higashiwaki K, Masuda K, Katsumi H, Yamamoto A.	Mol Pharm	10.1021/acs.molpharmaceut.3c00460	2023
	Dual Bioconversion Strategy: Synergistic Germination and Lactobacillus Fermentation Engineering for a gamma-Aminobutyric Acid-Enriched Beverage from Brown Rice	Yuan D, Zhang S, Hong B, Shan S, Zhang J, Sha D, Gao S, Liu Q, Lu S, Ren C.	Foods		2025
	The effect of oral nutritional supplementation combined with probiotics on the liver function and intestinal microflora in lung cancer chemotherapy patients through the gut-liver axis.	Li X, Gong W, Tang K, Kang J, Song F, Wang Y.	Sci Rep	10.1038/s41598-025-95005-x	2025
	Cell free supernatants of Bifidobacterium adolescentis and Bifidobacterium longum suppress the tumor growth in colorectal cancer organoid model.	Kim MJ, Song MH, Ji YS, Park JW, Shin YK, Kim SC, Kim G, Cho B, Park H, Ku JL, Jeong SY.	Sci Rep	10.1038/s41598-024-83048-5	2025
	"Protective effects of artichoke extract and Bifidobacterium longum on male infertility in diabetic rats".	Ansari Z, Maleki MH, Roohy F, Ebrahimi Z, Shams M, Mokaram P, Zamanzadeh Z, Hosseinzadeh Z, Koohpeyma F, Dastghaib S.	Biochem Biophys Rep	10.1016/j.bbrep.2024.101834	2024
	Versatile inulin/trans-ferulic acid/silk sericin nanoparticles-nourished probiotic complex with prolonged intestinal retention for synergistic therapy of inflammatory bowel disease	Zhang Y, Zhang X, Lv L, Gao S, Li X, Wang R, Wang P, Shi F, She J, Wang Y.	Carbohydrate polymers.		2024
Pathogenicity	The effects of probiotic supplements on oxidative stress and inflammation in subjects with mild and moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled study.	Akhgarjand C, Vahabi Z, Shab-Bidar S, Anoushirvani A, Djafarian K.	Inflammopharmacology	10.1007/s10787-023-01427-2	2024
	Characterization of the preweaned Holstein calf fecal microbiota prior to, during, and following resolution of uncomplicated gastrointestinal disease.	Claus-Walker RA, Slanzon GS, Elder LA, Hinnant HR, Mandella CM, Parrish LM, Trombetta SC, McConnel CS.	Front Microbiol	10.3389/fmicb.2024.1388489	2024
	Supplementing infant milk formula with a multi-strain synbiotic and osteopontin enhances colonic microbial colonization and modifies jejunal gene expression in lactating piglets.	Ferreres-Serafini L, Martin-Orue SM, Sadurni M, Jimenez J, Moreno-Munoz JA, Castillejos L.	Food Funct	10.1039/d4fo00489b	2024
	The impact of prebiotics, probiotics and synbiotics on the prevention and treatment of atopic dermatitis in children: an umbrella meta-analysis.	Wang L, Xu L.	Front Pediatr	10.3389/fped.2025.1498965	2025
	Eggerthella lenta down regulated flavone and flavonol biosynthesis promoted Kawasaki disease.	Yeh YT, Chen KD, Huang CH, Tsai JR, Kuo HC.	Virulence	10.1080/21505594.2025.2512401	2025
	Bifidobacterium longum JBLC-141 alleviates hypobaric hypoxia-induced intestinal barrier damage by attenuating inflammatory responses and oxidative stress.	Li XY, Shang J, Wang XJ, Ma HP, Ren LF, Zhang L.	Front Microbiol	10.3389/fmicb.2024.1501999	2024
	Role of the gut microbiome in psychological symptoms associated with inflammatory bowel diseases.	Atanasova K, Knodler LL, Reindl W, Ebert MP, Thomann AK.	Semin Immunopathol	10.1007/s00281-025-01036-x	2025
	In vitro faecal fermentation metabolites of 2'-fucosyllactose protect against intestinal epithelial injury: Infant enterotype effects	Gu Z, Xu S, Zheng Y, Lane JA, Dhital S, Huang Q, Hu R, Liu F, Zhang B.	Int Dairy J		2023
Pathogenicity	The effect of probiotic-fortified kefir on depression, appetite, oxidative stress, and inflammatory parameters in Iranian overweight and obese elderly: a randomized, double-blind, placebo-controlled clinical trial.	Noori M, Shateri Z, Babajafari S, Eskandari MH, Parastouei K, Ghasemi M, Afshari H, Samadi M.	J Health Popul Nutr	10.1186/s41043-025-00773-x	2025
	Gut microbial and clinical characteristics of individuals with autism spectrum disorder differ depending on the ecological structure of the gut microbiome.	Jung Y, Lee T, Oh HS, Hyun Y, Song S, Chun J, Kim HW.	Psychiatry Res	10.1016/j.psychres.2024.115775	2024
	Entrapment of probiotic (Bifidobacterium longum) in bilayer emulsion film with enhanced barrier property for improving viability.	Yang Z, Li M, Li Y, Wang X, Li Z, Shi J, Huang X, Zhai X, Zou X, Gong Y, Holmes M, Povey M, Xiao J.	Food Chem	10.1016/j.foodchem.2023.136300	2023
	Optimization of a novel dental self-healing resin composite by bacteria-induced biomineralization.	Han Y, Zhang X, Weng J, Tian S, Dong X, Cai Z, Zhang Y, Wu T, Lin D, Zhu Y.	Front Bioeng Biotechnol	10.3389/fbioe.2025.1590348	2025
	Metagenomic analysis of blood microbiota alterations: insights into HIV progression and immune restoration.	Chen Y, Zhang R, Wen J, Zhao J, Zhang J.	Front Cell Infect Microbiol	10.3389/fcimb.2025.1619059	2025
	Effects of Probiotics as Adjunctive Therapy to Fluoxetine on Depression Severity and Serum Brain-Derived Neurotrophic Factor, Cortisol, and Adrenocorticotropic Hormone in Patients With Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled Trial.	Elahinejad V, Khorasanian AS, Tehrani-Doost M, Khosravi-Darani K, Mirsepasi Z, Effatpanah M, Askari-Rabori R, Tajadod S, Jazayeri S.	Food Sci Nutr	10.1002/fsn3.4698	2025
	Immune microenvironment-dependent effects of age-associated Bifidobacterium strains on gut immunity and microbial diversity.	He Y, Zhang F, Tian Z, Li R, Su M, Hong L, Wen J, Zhang C, Tian J, Guo L.	Front Cell Infect Microbiol	10.3389/fcimb.2025.1639178	2025
	Proteomic analyses of Bacteroides ovatus and Bifidobacterium longum in xylan bidirectional culture shows sugar cross-feeding interactions.	Vega-Sagardia M, Delgado J, Ruiz-Moyano S, Garrido D.	Food Res Int	10.1016/j.foodres.2023.113025	2023
Pathogenicity	Effects of Probiotics on Neurodegenerative Disease-Related Symptoms and Systemic Inflammation: A Systematic Review.	Zhu F, Yin S, Wang Y, Zhong Y, Ji Q, Wu J.	Int J Gen Med	10.2147/ijgm.s499406	2024
	Untargeted metabolomic analysis uncovers metabolic variability of four Bifidobacterial strains for probiotic development.	Liu K, Yao G, Yang Z, Huang T, Kwok LY, Zhang H.	Front Microbiol	10.3389/fmicb.2025.1522036	2025
	Uptake of fucosylated type I human milk oligosaccharide blocks by Bifidobacterium longum subsp. infantis.	Ejby Hansen M, Sakanaka M, Jensen M, Sakanaka H, Pichler MJ, Maeda S, Franck Hovring J, Nakajima A, Kunstmann S, Nielsen TS, Peters GHJ, Slotboom DJ, Morth JP, Katayama T, Abou Hachem M.	mBio	10.1128/mbio.00368-25	2025
	The potential of the microbiome as a target for prevention and treatment of carbapenem-resistant Enterobacteriaceae infections.	Zhang L, Xu T, Chen W, Chai Y, Wu Y, Du X.	Front Cell Infect Microbiol	10.3389/fcimb.2025.1674534	2025
Genetics	Structural and functional characterization of gut microbiota in dyslipidemic patients from high-altitude Tibetan pastoral areas.	Chen J, Luo Y, Hao Y, Wang Q, Wang Q.	Front Nutr	10.3389/fnut.2025.1676238	2025
	Screening competition and cross-feeding interactions during utilization of human milk oligosaccharides by gut microbes.	Diaz R, Garrido D.	Microbiome Res Rep	10.20517/mrr.2023.61	2024
	Effects of Mesalamine Combined with Live Combined Bifidobacterium, Lactobacillus and Enterococcus Capsules on Intestinal Mucosa Barrier Function and Intestinal Microbiota in Mildly Active Crohn's Disease Patients.	Shen M, Shi Y, Ge Z, Qian J.	J Invest Surg	10.1080/08941939.2023.2297565	2024
	Therapeutic Potential of Bifidobacterium longum subsp. infantis B8762 on Gut and Respiratory Health in Infant.	Richmond RV, Mageswary U, Ali A, Taib F, Koo TH, Yusof A, Hamid IJA, Zhao F, Rahman NNNA, Hasan TH, Zhang H, Liong MT.	Int J Mol Sci	10.3390/ijms26031323	2025
	Intestinal Bacteria Fluctuating in Early-Stage Colorectal Cancer Carcinogenesis are Associated with Diet in Healthy Adults.	Narii N, Zha L, Sobue T, Kitamura T, Komatsu M, Shimomura Y, Shiba S, Mizutani S, Yamada T, Yachida S.	Nutr Cancer	10.1080/01635581.2024.2344257	2024
	Arabinoxylan-based substrate preferences and predicted metabolic properties of Bifidobacterium longum subspecies as a basis to design differential media	Calvete-Torre I, Sabater C, Delgado S, Ruas-Madiedo P, Ruperez-Garcia A, Montilla A, Javier Moreno F, Margolles A, Ruiz L.	Food Research International.		2023
	In Vitro Screening of Trehalose Synbiotics and Their Effects on Early-Lactating Females and Offspring Mice.	Peng H, Guo Y, Zhang J, Hei M, Li Y, Zhang W.	Antioxidants (Basel)	10.3390/antiox13101223	2024
	L-Citrulline Improves Recovery of Enterocytes While Not Affecting Gut Microbiota in an In Vitro Model of Chemotherapy-Induced Gastrointestinal Mucositis.	van der Laan W, Gallardo Molina PA, Koonen DPY, Harmsen HJM, Tissing WJE.	Biomedicines	10.3390/biomedicines13092244	2025
	Multi-strain probiotic improves subjective sleep quality with no impact on body composition, hemodynamics, and physical activity.	Kerksick CM, Moon JM, Walden KE, Hagele AM, Allen LE, Gaige CJ, Krieger JM, Jager R, Pane M, Mumford P.	Benef Microbes	10.1163/18762891-bja00002	2024
	Gut microbiota as a novel target for treating anxiety and depression: from mechanisms to multimodal interventions.	Ruohan Z, Ruting W, Hongxi W, Zhenjin H, Jiale L, Rongxin Z, Feng J, Yuanbo S.	Front Microbiol	10.3389/fmicb.2025.1664800	2025
	Selenium-enriched Bifidobacterium longum DD98 relieves irritable bowel syndrome induced by chronic unpredictable mild stress in mice.	Jin X, Hu Y, Lin T, Gao F, Xu Z, Hou X, Yin Y, Kan S, Zhu H, Chen D.	Food Funct	10.1039/d2fo03408e	2023
	Probiotic-based self-crosslinking bio-coating for the treatment of colitis by increasing probiotic colonization.	Shi S, Li B, Zhang Y, Li Z, Cui Y, Ma C, Zhang X, Liu S, Zhou B.	Mater Today Bio	10.1016/j.mtbio.2025.102447	2025
	The Impact of Gut Microbiota on the Development of Anxiety Symptoms-A Narrative Review.	Nikel K, Stojko M, Smolarczyk J, Piegza M.	Nutrients	10.3390/nu17060933	2025
	Bifidobacterium longum R0175 protects mice against APAP-induced liver injury by modulating the Nrf2 pathway.	Li S, Zhuge A, Xia J, Wang S, Lv L, Wang K, Jiang H, Yan R, Yang L, Bian X, Jiang X, Wang Q, Han S, Li L.	Free Radic Biol Med	10.1016/j.freeradbiomed.2023.03.026	2023
	Strain-specific effects of probiotics on depression and anxiety: a meta-analysis.	Rahmannia M, Poudineh M, Mirzaei R, Aalipour MA, Shahidi Bonjar AH, Goudarzi M, Kheradmand A, Aslani HR, Sadeghian M, Nasiri MJ, Sechi LA.	Gut Pathog	10.1186/s13099-024-00634-8	2024
	Characterization of the Gut Microbiota in Patients with Psoriasis: A Systematic Review.	Gao Y, Lou Y, Hui Y, Chen H, Sang H, Liu F.	Pathogens	10.3390/pathogens14040358	2025
	Benefit of Probiotics on Cardiovascular Health- A Narrative Review.	Mathur A, Malik S, Ganti L.	Health Psychol Res	10.52965/001c.123856	2024
	Isolation, identification, and in vitro probiotic characterization of forty novel Bifidobacterium strains from neonatal feces in Erzurum province, Türkiye.	Guler MA, Cetin B, Albayrak B, Meral-Aktas H, Tekgunduz KS, Kara M, Islek A.	J Sci Food Agric	10.1002/jsfa.13298	2024
	Effects of Probiotic Use on Gastrointestinal Symptoms in the Late Postoperative Period of Bariatric Surgery: A Cross-Over, Randomized, Triple-Blind, Placebo-Controlled Study.	Wagner NRF, Lopes MCP, Fernandes R, Taconelli CA, Nascimento GM, Pessini J, Trindade EBSM, Campos ACL.	Obes Surg	10.1007/s11695-024-07117-4	2024
Genetics	Direct-fed microbials optimize ruminal fermentation, microbial ecosystem and milk quality to enhance the lactation performance of Sanhe dairy cows.	Jiang A, Liu Z, Yang Z, Zhang S, Wu J, Zhou C, Tan Z.	Anim Microbiome	10.1186/s42523-025-00437-5	2025
	Effects of Heat-Treated Bifidobacterium longum CECT-7347 Combined with Fibersol-2 on the Intestinal Health of Cats Submitted to an Abrupt Dietary Change: A Randomized Controlled Study.	Wang F, Gao S, Peng Q, Tan L, Chen S, Xia Z.	Animals (Basel)	10.3390/ani14152179	2024
	Maternal-to-neonatal microbial transmission and impact of prenatal probiotics on neonatal gut development.	Meng L, Fan G, Xie H, Tye KD, Xia L, Luo H, Tang X, Huang T, Lin J, Ma G, Xiao X, Li Z.	J Transl Med	10.1186/s12967-025-07293-6	2025
	Marked reduction of SARS-CoV-2 infection and improved recovery following supplementation with a probiotic mix of four strains and two strains of Bifidobacterium breve in hamsters.	Torres-Maravilla E, Wasniewski M, Wauquier A, Servat A, Picard-Meyer E, Monchatre-Leroy E, Auger S, Holowacz S, Boue F, Langella P, Jacouton E, Waligora-Dupriet A-J.	Appl Environ Microbiol	10.1128/aem.00648-25	2025
	Role of Gut Microbiota and Metabolomics in Predicting Response to Vedolizumab in Inflammatory Bowel Disease: A Systematic Review.	Malinauskiene V, Cijauskaite E, Sadauskaite G, Stundiene I.	Pharmaceutics	10.3390/pharmaceutics17040476	2025
Metabolism	Intratumoral microbial heterogeneity in HCC reveals a potential therapeutic target.	Li L, Wang M, Jiang Z, Yi C, Yi Y.	JHEP Rep	10.1016/j.jhepr.2025.101538	2025
	Real-time PCR methods for identification and stability monitoring of Bifidobacterium longum subsp. longum UABl-14 during shelf life.	Shehata HR, Hassane B, Newmaster SG.	Front Microbiol	10.3389/fmicb.2024.1360241	2024
	Comparative in silico analyses between Lactiplantibacillus plantarum and Bifidobacterium longum concerning probiotic properties, anti-lipidemic, and anti-diabetic in vitro activities.	El-Dein AN, Alshehri WA, Khalel AF, Awad HM.	BMC Microbiol	10.1186/s12866-025-04062-9	2025
	Proteomic study of Akkermansia muciniphila and Bifidobacterium species co-culture under different carbon sources.	Sulaiman JE, Zhan Y, Wang S, Lai KL, Li JHW, Yutong DY, Tsim KWK, Cheng KKY, Lai Y, Lam H.	Front Microbiol	10.3389/fmicb.2025.1666747	2025
	In vitro assessment of bacterial supernatants on hypothalamic gene expression: implications for appetite regulation.	Cuesta-Marti C, Valderrama B, Bastiaanssen T, Cryan JF, Stanton C, O'Mahony SM, Clarke G, Schellekens H.	NPJ Biofilms Microbiomes	10.1038/s41522-025-00820-9	2025
	Gut microbiota modulation, prebiotic and bioactive characteristics of date pomace polysaccharides extracted by microwave-assisted deep eutectic solvent.	Bamigbade GB, Subhash AJ, Al-Ramadi B, Kamal-Eldin A, Gan RY, Liu SQ, Ayyash M.	Int J Biol Macromol	10.1016/j.ijbiomac.2024.130167	2024
	A metabolomics-driven model for early remission prediction following vedolizumab treatment in patients with moderate-to-severe active ulcerative colitis.	Jiang L, Liu X, Su Y, Chen Y, Yang S, Ke X, Yao K, Guo Z.	Int Immunopharmacol	10.1016/j.intimp.2024.111527	2024
Enzymology	Ambient temperature structure of phosphoketolase from Bifidobacterium longum determined by serial femtosecond X-ray crystallography.	Nakata K, Kashiwagi T, Kunishima N, Naitow H, Matsuura Y, Miyano H, Mizukoshi T, Tono K, Yabashi M, Nango E, Iwata S.	Acta Crystallogr D Struct Biol	10.1107/s2059798323001638	2023
	Lactobacillus plantarum and Bifidobacterium longum Alleviate High-Fat Diet-Induced Obesity and Depression/Cognitive Impairment-like Behavior in Mice by Upregulating AMPK Activation and Downregulating Adipogenesis and Gut Dysbiosis.	Yun SW, Shin YJ, Ma X, Kim DH.	Nutrients	10.3390/nu16223810	2024
Metabolism	Carrot-Derived Rhamnogalacturonan-I Consistently Increases the Microbial Production of Health-Promoting Indole-3-Propionic Acid Ex Vivo.	Mercenier A, Vu LD, Poppe J, Albers R, McKay S, Van den Abbeele P.	Metabolites	10.3390/metabo14120722	2024
	The microbiota and the host organism switch between cooperation and competition based on dietary iron levels.	Noordine ML, Seyoum Y, Bruneau A, Baye K, Lefebvre T, Cherbuy C, Canonne-Hergaux F, Nicolas G, Humblot C, Thomas M.	Gut Microbes	10.1080/19490976.2024.2361660	2024
Genetics	Metagenomics Analysis Reveals Unique Gut Microbiota Signature of Slow-Transit Constipation.	Han K, Kuo B, Khalili H, Staller K.	Clin Transl Gastroenterol	10.14309/ctg.0000000000000766	2024
	Synbiotics as a novel therapeutic approach for hyperphosphatemia and hyperparathyroidism in chronic kidney disease rats.	Anegkamol W, Bowonsomsarit W, Taweevisit M, Tumwasorn S, Thongsricome T, Kaewwongse M, Pitchyangkura R, Tosukhowong P, Chuaypen N, Dissayabutra T.	Sci Rep	10.1038/s41598-025-91033-9	2025
	Arabinoxylan-based substrate preferences and predicted metabolic properties of Bifidobacterium longum subspecies as a basis to design differential media.	Calvete-Torre I, Sabater C, Delgado S, Ruas-Madiedo P, Ruperez-Garcia A, Montilla A, Javier Moreno F, Margolles A, Ruiz L.	Food Res Int	10.1016/j.foodres.2023.112711	2023
	Effects of Biofilm Formation on Gastrointestinal Tolerance, Mucoadhesion and Transcriptomic Responses of Probiotics.	Gao W, Jing H, Qiu B, Zhang S, Zhang J, Xu L, Ba F, Xie S, Liu XM, Li L, Yao M.	Food Sci Nutr	10.1002/fsn3.70206	2025
Pathogenicity	Implication of microbiota gut-brain axis in the manifestation of obsessive-compulsive disorder: Preclinical and clinical evidence.	Kamble SR, Dandekar MP.	Eur J Pharmacol	10.1016/j.ejphar.2023.176014	2023
	The effects of candidate probiotic strains on the gut environment in dextran sulfate sodium-induced colitis mouse.	Ahn K, Baek KW, Yun K, Oh Y, Kim YS, Im E, Lee Y, Choi J, Song EJ, Park YS, Lee DH, Lee W, Lee DY, Han K, Ahn YJ.	Sci Rep	10.1038/s41598-025-03860-5	2025
	Efficacy of encapsulated fecal microbiota transplantation and FMT via rectal enema for irritable bowel syndrome: a double-blind, randomized, placebo-controlled trial (CAP-ENEMA FMT Trial).	Aumpan N, Chonprasertsuk S, Pornthisarn B, Siramolpiwat S, Bhanthumkomol P, Issariyakulkarn N, Gamnarai P, Bongkotvirawan P, Wongcha-Um A, Mahachai V, Vilaichone RK.	Front Med (Lausanne)	10.3389/fmed.2025.1648944	2025
	Effects of the fermentation process on the selenite metabolism and selenium incorporation and speciation in a probiotic Bifidobacterium longum.	Zhu H, Bierla K, Tan J, Szpunar J, Chen D, Lobinski R.	Metallomics	10.1093/mtomcs/mfac100	2023
	Probiotic Consortia Protect the Intestine Against Radiation Injury by Improving Intestinal Epithelial Homeostasis.	Xie LW, Lu HY, Tang LF, Tang FL, Zhu RQ, Wang DF, Cai S, Tian Y, Li M.	Int J Radiat Oncol Biol Phys	10.1016/j.ijrobp.2024.03.003	2024
	The Role and the Regulation of NLRP3 Inflammasome in Irritable Bowel Syndrome: A Narrative Review.	Kasti A, Katsas K, Nikolaki MD, Triantafyllou K.	Microorganisms	10.3390/microorganisms13010171	2025
	Meta-analysis reveals different functional characteristics of human gut Bifidobacteria associated with habitual diet.	Yin P, Zhang C, Du T, Yi S, Yu L, Tian F, Chen W, Zhai Q.	Food Res Int	10.1016/j.foodres.2023.112981	2023
	Efficacy and safety of probiotic supplements on cognitive function: a systematic review and meta-analysis of randomized clinical trials.	Calzada-Gonzales N, Moreno-Colina I, Chu-Fuentes L, Andrade-Giron D, Tito-Chura HE, Quispe-Vicuna C, Torres-Balarezo PI, Bautista-Pariona A, Barboza JJ.	BMC Complement Med Ther	10.1186/s12906-025-05149-6	2025
	Bifidobacterium longum subsp. infantis FJSYZ1M3 ameliorates DSS-induced colitis by maintaining the intestinal barrier, regulating inflammatory cytokines, and modifying gut microbiota.	Li M, Ding J, Stanton C, Ross RP, Zhao J, Yang B, Chen W.	Food Funct	10.1039/d2fo03263e	2023
	Evaluating the prebiotic activity of arabinogalactan on the human gut microbiota using 16S rRNA gene sequencing and Raman-activated cell sorting.	Rasoulimehrabani H, Khadem S, Hodzic A, Philipp M, Gallo R, Nikolov G, Seneca J, Ramesmayer J, Sivulic P, Berry D.	Microbiome Res Rep	10.20517/mrr.2025.29	2025
Genetics	Priority effects, nutrition and milk glycan-metabolic potential drive Bifidobacterium longum subspecies dynamics in the infant gut microbiome.	Pucci N, Ujcic-Voortman J, Verhoeff AP, Mende DR.	PeerJ	10.7717/peerj.18602	2025
Genetics	ParallelEvolCCM: Quantifying Coevolutionary Patterns Among Genomic Features.	Beiko RG, Liu C, Cavalcante JV, Fink RC.	Genome Biol Evol	10.1093/gbe/evaf092	2025
	Artificial-enzymes-armed Bifidobacterium longum probiotics for alleviating intestinal inflammation and microbiota dysbiosis.	Cao F, Jin L, Gao Y, Ding Y, Wen H, Qian Z, Zhang C, Hong L, Yang H, Zhang J, Tong Z, Wang W, Chen X, Mao Z.	Nat Nanotechnol	10.1038/s41565-023-01346-x	2023
	The Effect of the Combination of Two Postbiotics on Anxiety-like Behavior in Animal Models.	Robles V, Balaguer F, Maicas M, Martinez-Vazquez JM, Martorell P, Tortajada M, Ramon D, Valcarce DG.	Cells	10.3390/cells13232006	2024
	Bifidobacterium longum increases serum vitamin D metabolite levels and modulates intestinal flora to alleviate osteoporosis in mice.	Wang H, Tian G, Pei Z, Yu X, Wang Y, Xu F, Zhao J, Lu S, Lu W.	mSphere	10.1128/msphere.01039-24	2025
	Meta-analysis reveals different functional characteristics of human gut Bifidobacteria associated with habitual diet	Yin P, Zhang C, Du T, Yi S, Yu L, Tian F, Chen W, Zhai Q.	Food Research International.		2023
	Evaluation of the Effect of Probiotic Supplementation on Intestinal Barrier Integrity and Epithelial Damage in Colitis Disease: A Systematic Review.	Sivri D, Seref B, Sare Bulut M, Gezmen Karadag M.	Nutr Rev	10.1093/nutrit/nuae180	2025
	Breastfeeding patterns and total volume of human milk consumed influence the development of the infant oral microbiome.	Arishi RA, Gridneva Z, Perrella SL, Cheema AS, Lai CT, Payne MS, Geddes DT, Stinson LF.	J Oral Microbiol	10.1080/20002297.2025.2469892	2025
	Probiotic Bifidobacterium longum Subsp. longum 5^1A Protects Mice from Genotoxic and Metabolic Alterations Induced by Subchronic Exposure to a Low-Dose Pesticide Cocktail.	Maciel d'Auriol Souza M, Mendes de Almeida V, Silva Cruz C, de Melo Rocha V, Lacerda Leocardio PC, Araujo Pires S, do Vale Oliveira M, Brumate T, Nunes de Paiva MJ, Alvarez-Leite JI, Dantas Cassali G, Santos Martins F, Thomaz Vieira A, Coelho Andre L.	ACS Omega	10.1021/acsomega.5c04121	2025
	Research status and development trends of probiotics in clinical applications.	Li Y, Yao Y, Zhang Z, Gan Y.	Front Nutr	10.3389/fnut.2025.1650883	2025
	Mechanistic insights into the structure-dependant and strain-specific utilization of wheat arabinoxylan by Bifidobacterium longum	Song AX, Li LQ, Yin JY, Chiou JC, Wu JY.	Carbohydrate polymers.		2022
	A key genetic factor governing arabinan utilization in the gut microbiome alleviates constipation.	Zhang C, Yu L, Ma C, Jiang S, Zhang Y, Wang S, Tian F, Xue Y, Zhao J, Zhang H, Liu L, Chen W, Huang S, Zhang J, Zhai Q.	Cell Host Microbe	10.1016/j.chom.2023.10.011	2023
	BCL-2 Multi-Strain Probiotics for Immunomodulation In Vitro and In Vivo Alleviation of Atopic Dermatitis	Sung M, Sim S, Lim A, Moon J, Jeon J, Heo K, Kwak W, Park M, Kwak J, Park E, Yoon S.	Microorganisms		2025
	Effects of Bifidobacterium longum 35624 in Children and Adolescents with Irritable Bowel Syndrome	Cruchet Munoz S, Verbeke Palma S, Lera Marques L, Espinosa Pizarro M, Malig Mechasqui J, Sorensen K.	Nutrients		2024
	Bifidobacterium longum CCFM1206 Promotes the Biotransformation of Glucoraphanin to Sulforaphane That Contributes to Amelioration of Dextran-Sulfate-Sodium-Induced Colitis in Mice.	Wu J, Cui S, Tang X, Zhang Q, Jin Y, Zhao J, Mao B, Zhang H.	J Agric Food Chem	10.1021/acs.jafc.2c07090	2023
	Individual and Combined Effects of 2'-Fucosyllactose and Bifidobacterium longum subsp. infantis on the Gut Microbiota Composition of Piglets.	Wang M, Monaco MH, Daniels VC, Hirvonen J, Jensen HM, Ouwehand AC, Mukherjea R, Christensen N, Lehtinen MJ, Hibberd AA, Dilger RN, Donovan SM.	J Nutr	10.1016/j.tjnut.2024.12.022	2025
	Effect of Probiotic Supplementation on the Gut Microbiota Composition of Infants Delivered by Cesarean Section: An Exploratory, Randomized, Open-label, Parallel-controlled Trial.	Gong Y, Zhong H, Wang J, Wang X, Huang L, Zou Y, Qin H, Yang R.	Curr Microbiol	10.1007/s00284-023-03444-4	2023
Pathogenicity	A Symbiotic Meal Containing Extruded Sorghum and Probiotic (Bifidobacterium longum) Ameliorated Intestinal Health Markers in Individuals with Chronic Kidney Disease: A Secondary Analysis of a Subsample from a Previous Randomized and Controlled Clinical Trial	Lucio H, Lopes R, Gomes M, da Silva A, Grancieri M, Della Lucia C, Queiroz V, da Silva B, Martino H.	Nutrients		2024
Genetics	Microbial metagenomic shifts in children with acute lymphoblastic leukaemia during induction therapy and predictive biomarkers for infection.	Wang H, Zhang Y, Zhou Q, Yu L, Fu J, Lin D, Huang L, Lai X, Wu L, Zhang J, Zi J, Liao X, Huang S, Xie Y, He Y, Yang L.	Ann Clin Microbiol Antimicrob	10.1186/s12941-024-00717-z	2024
	Ex-vivo investigation of probiotic bacterial adhesion to the intestinal mucus.	Phung TT, Dupont S, Beney L, Moundanga S, Denimal E, Ho PH, Karbowiak T.	Heliyon	10.1016/j.heliyon.2024.e36339	2024
	Efficacy and Safety of Bifidobacterium longum Supplementation in Infants: A Meta-Analysis of Randomized Controlled Trials.	Guo H, Fan M, Hou T, Li Y, Wang S, Wang X, Peng H, Wang M, Wu T, Zhang Y.	Foods	10.3390/foods12244451	2023
	Efficacy of Bifidobacterium longum and Lactobacillus plantarum (NVP-1703) in Children With Allergic Rhinitis: A Randomized Controlled Trial.	Jeong K, Jang SW, Jeon SA, Seo HJ, Kang SH, Han SW, Suh DI, Lee S.	J Korean Med Sci	10.3346/jkms.2024.39.e266	2024
Phylogeny	Diversity and Functional Predictions of Gut Microbiota in Vietnamese Children Aged 6-24 Months with Persistent Diarrhea of Unknown Etiology.	Pham TTN, Dao TK, Nguyen TVH, Phung TBT, Nguyen HD, Nguyen TQ, Le TTH, Do TH.	Pathogens	10.3390/pathogens14111136	2025
Phylogeny	Effects of Sequential Antimicrobial Phases on Root Canal Microbiome Dynamics in Two-Visit Treatment of Primary Apical Periodontitis: A Longitudinal Experimental Study.	Kesim B, Tezcan Ulger S, Aslan G, Ustun Y, Avci AT, Kucuk MO.	Life (Basel)	10.3390/life14121696	2024
	Can We Modulate Our Second Brain and Its Metabolites to Change Our Mood? A Systematic Review on Efficacy, Mechanisms, and Future Directions of "Psychobiotics".	Garzone S, Charitos IA, Mandorino M, Maggiore ME, Capozzi L, Cakani B, Dias Lopes GC, Bocchio-Chiavetto L, Colella M.	Int J Mol Sci	10.3390/ijms26051972	2025
	The impact of probiotic administration on experimental in vitro and in vivo infection by Trypanosoma cruzi.	Batista DDGJ, Missagia LC, Demarque KC, de Oliveira GM, Batista MM, Soeiro MNC.	Mem Inst Oswaldo Cruz	10.1590/0074-02760240272	2025
Metabolism	The role of probiotics in adolescents' obesity.	Chen XP, You L, Jia Y.	Front Cell Infect Microbiol	10.3389/fcimb.2025.1546627	2025
	A synbiotic combination of Bifidobacterium longum Bif10 and Bifidobacterium breve Bif11, isomaltooligosaccharides and finger millet arabinoxylan prevents dextran sodium sulphate induced ulcerative colitis in mice.	Sharma S, Bhatia R, Devi K, Rawat A, Singh S, Bhadada SK, Bishnoi M, Sharma SS, Kondepudi KK.	Int J Biol Macromol	10.1016/j.ijbiomac.2023.123326	2023
Metabolism	Gut microbiome alterations and hepatic encephalopathy post-TIPS in liver cirrhosis patients.	Li S, Xu Z, Diao H, Zhou A, Tu D, Wang S, Feng Y, Feng X, Lai Y, Yang S, Tang B.	J Transl Med	10.1186/s12967-025-06774-y	2025
	Probiotic Bifidobacterium reduces serum TMAO in unstable angina patients via the gut to liver to heart axis.	Zhou Z, Sun L, Zhou W, Gao W, Yuan X, Zhou H, Ren Y, Li B, Wu Y, She J.	Liver Res	10.1016/j.livres.2025.02.001	2025
Genetics	Characterization of an EPS-producing bifidobacterial strain based on integration of phenotypic and complete genome sequencing data.	Liu D, Huang H, Han J, Wu Q, Xiang Y, Liu Y, Wei Y.	Can J Microbiol	10.1139/cjm-2023-0025	2023
	Cinnamon (Cinnamomum cassia) water extract improves diarrhea symptoms by changing the gut environment: a randomized controlled trial.	Park SY, Kim YD, Kim MS, Kim KT, Kim JY.	Food Funct	10.1039/d2fo01835g	2023
	L. plantarum UBLP-40 Versus the Combined Formula of L. rhamnosus UBLP-58 and B. longum UBBL-64 in Excisional Wound Healing: A Cellular Perspective.	Moysidis M, Chorti A, Cheva A, Abba Deka I, Tzikos G, Kosmidis C, Koutelidakis I, Tsetis JK, Papavramidis T, Kotzampassi K.	Pharmaceuticals (Basel)	10.3390/ph17111414	2024
	From gut to brain: unveiling probiotic effects through a neuroimaging perspective-A systematic review of randomized controlled trials.	Crocetta A, Liloia D, Costa T, Duca S, Cauda F, Manuello J.	Front Nutr	10.3389/fnut.2024.1446854	2024
	Bifidobacterium deficit in United States infants drives prevalent gut dysbiosis.	Jarman JB, Torres PJ, Stromberg S, Sato H, Stack C, Ladrillono A, Pace S, Jimenez NL, Haselbeck RJ, Insel R, Van Dien S, Culler SJ.	Commun Biol	10.1038/s42003-025-08274-7	2025
	Microbiome analysis of gut microbiota in patients with colorectal polyps and healthy individuals.	Deng D, Zhao L, Song H, Wang H, Cao H, Cui H, Zhou Y, Cui R.	Sci Rep	10.1038/s41598-025-91626-4	2025
	Rewiring Mood: Precision Psychobiotics as Adjunct or Stand-Alone Therapy in Depression Using Insights from 19 Randomized Controlled Trials in Adults.	Menni AE, Theodorou H, Tzikos G, Theodorou IM, Semertzidou E, Stelmach V, Shrewsbury AD, Stavrou G, Kotzampassi K.	Nutrients	10.3390/nu17122022	2025
	Probiotics improve polystyrene microplastics-induced male reproductive toxicity in mice by alleviating inflammatory response.	Zhang Y, Hou B, Liu T, Wu Y, Wang Z.	Ecotoxicol Environ Saf	10.1016/j.ecoenv.2023.115248	2023
	Synbiotics production using Lactobacillus reuteri EC01, a strain that produces alternan-type exopolysaccharide	Ju JH, Jeon SG, Heo SY, Kim JS, Jo MH, Kim Ms, Kim CH, Oh BR.	Lebensm Wiss Technol		2023
Genetics	Metagenomic analysis revealed the association between gut microbiota and different ovary responses to controlled ovarian stimulation.	Fo X, Pei ML, Liu PJ, Zhu F, Zhang Y, Mu X.	Sci Rep	10.1038/s41598-024-65869-6	2024
	Synbiotics as Treatment for Irritable Bowel Syndrome: A Review.	Sommermeyer H, Piatek J.	Microorganisms	10.3390/microorganisms12071493	2024
	Sex Difference in the Effect of Bifidobacterium longum on Repeated Water Avoidance Stress-induced Gut Dysbiosis in Wistar Rats.	Choi SI, Kim N, Nam RH, Jang JY, Kim EH, Ha S, Kang K, Lee W, Shin CM, Lee DH.	J Cancer Prev	10.15430/jcp.23.042	2024
Metabolism	Effects of Bifidobacterium-Fermented Milk on Obesity: Improved Lipid Metabolism through Suppression of Lipogenesis and Enhanced Muscle Metabolism.	Maruta H, Fujii Y, Toyokawa N, Nakamura S, Yamashita H.	Int J Mol Sci	10.3390/ijms25189934	2024
	Optimal beta-galactosidases for producing high-titer 3,6-anhydro-L-galactose from red-algal agarobiose.	Kim DH, Park SY, Kim KH.	Appl Microbiol Biotechnol	10.1007/s00253-022-12274-6	2022
	Combining Bifidobacterium longum subsp. infantis and human milk oligosaccharides synergistically increases short chain fatty acid production ex vivo.	De Bruyn F, James K, Cottenet G, Dominick M, Katja J.	Commun Biol	10.1038/s42003-024-06628-1	2024
	The antidiabetic effects of Bifidobacterium longum subsp. longum BL21 through regulating gut microbiota structure in type 2 diabetic mice.	Hao J, Zhang Y, Wu T, Liu R, Sui W, Zhu J, Fang S, Geng J, Zhang M.	Food Funct	10.1039/d2fo01109c	2022
	Potential Role of Lactobacillus and Bifidobacterium for Preventing Kidney Stones.	Masoleh AM, Khoshnood S, Haddadi MH, Rostamzad A, Narki M, Hoshmandfar R, Sadeghifard N.	Clin Lab	10.7754/clin.lab.2022.220645	2023
	The association between greenery type and gut microbiome in schizophrenia: did all greenspaces play the equivalent role?	Wei N, Wang S, Li X, Pan R, Yi W, Song J, Liu L, Liu J, Yuan J, Song R, Cheng J, Su H.	Environ Sci Pollut Res Int	10.1007/s11356-023-29419-3	2023
	In vitro fermentation of human milk oligosaccharides by individual Bifidobacterium longum-dominant infant fecal inocula	Li H, Lane JA, Chen J, Lu Z, Wang H, Dhital S, Fuehrer B, Huang Q, Liu F, Zhang B.	Carbohydrate polymers.		2022
	A distinct clade of Bifidobacterium longum in the gut of Bangladeshi children thrives during weaning.	Vatanen T, Ang QY, Siegwald L, Sarker SA, Le Roy CI, Duboux S, Delannoy-Bruno O, Ngom-Bru C, Boulange CL, Strazar M, Avila-Pacheco J, Deik A, Pierce K, Bullock K, Dennis C, Sultana S, Sayed S, Rahman M, Ahmed T, Modesto M, Mattarelli P, Clish CB, Vlamakis H, Plichta DR, Sakwinska O, Xavier RJ.	Cell	10.1016/j.cell.2022.10.011	2022
	Bifidobacterial GH146 beta-l-Arabinofuranosidase (Bll4HypBA1) as the Last Enzyme for the Complete Removal of Oligoarabinofuranosides from Hydroxyproline-Rich Glycoproteins.	Ishiwata A, Tsunomachi H, Kameyama K, Sophon K, Nakamura M, Kitahara K, Tanaka K, Ito Y, Fujita K.	Chembiochem	10.1002/cbic.202200637	2023
	The Gut Microbiome and Vaccination: A Comprehensive Review of Current Evidence and Future Perspectives.	Gioula G, Exindari M.	Vaccines (Basel)	10.3390/vaccines13111116	2025
	Multiomics reveals the mechanism of B. longum in promoting the formation of mixed-species biofilms.	Xu T, Xiao Y, Wang H, Zhu J, Lu W, Chen W.	Food Funct	10.1039/d3fo01751f	2023
	The effectiveness of treatment with probiotics in preventing necrotizing enterocolitis and related mortality: results from an umbrella meta-analysis on meta-analyses of randomized controlled trials.	Han J, Ren Y, Zhang P, Fang C, Yang L, Zhou S, Ji Z.	BMC Gastroenterol	10.1186/s12876-025-03788-0	2025
Pathogenicity	Harnessing Metabolomics to Advance Nutrition-Based Therapeutics for Inflammation: A Systematic Review of Randomized Clinical Trials.	Carlino B, Guerrero-Flores GN, Niclis C, Segovia-Siapco G, Mayta ML.	Metabolites	10.3390/metabo15110705	2025
	Exploring the role of acylated ghrelin and gut microbiome in delineating cognitive health in the elderly.	Rout S, Dash R, Satish V, Venugopal G, Rao BN, Bandhyopadhyay D, Bhoi SK, Ramadass B.	Aging (Albany NY)	10.18632/aging.206200	2025
	A multi-strain probiotic formulation preserves intestinal epithelial and vascular barriers during enteropathogenic infection	Naso A, Lizier M, Correale C, Silvestri A, Penna G, Brescia P, Rescigno M.	Front Microbiol		2025
	Fermentation of Ganoderma lucidum and Raphani Semen with a probiotic mixture attenuates cyclophosphamide-induced immunosuppression through microbiota-dependent or -independent regulation of intestinal mucosal barrier and immune responses.	Li Y, Lei Z, Guo Y, Liu Y, Guo X, Wang X, Che J, Yuan J, Wang C, Li M.	Phytomedicine	10.1016/j.phymed.2023.155082	2023
	The Neurobehavioral Impact of Zinc Chloride Exposure in Zebrafish: Evaluating Cognitive Deficits and Probiotic Modulation.	Ene M, Savuca A, Ciobica AS, Jijie R, Gurzu IL, Hritcu LD, Chelaru IA, Plavan GI, Nicoara MN, Gurzu B.	Toxics	10.3390/toxics13030193	2025
Genetics	Draft genomes of 12 Bifidobacterium isolates from human IBD fecal samples.	Souza CE, Jacobson NE, An MA, Droit L, Vega AA, Rosales M, Mihindukulasuriya KA, Pastrana K, Handley SA, Parkes M, Rimmer J, Wang D, Dinsdale EA, A Edwards R, Segall AM.	Microbiol Resour Announc	10.1128/mra.00130-23	2024
	The Role of Probiotics in Modulating Myocardial Infarction and Depression-like Symptoms: A Study on Sex-Specific Responses.	Gagne MA, Fregeau G, Godbout R, Rousseau G.	Biomedicines	10.3390/biomedicines12112511	2024
	The anti-allergic effect of Lactobacillus plantarum GUANKE on allergic rhinitis induced by either ragweed pollen or house dust mites in mice.	Zhao P, Zhang B, Zhao LS, Yang Z, Li MD.	Front Nutr	10.3389/fnut.2025.1678249	2025
	The resident gut microbiome modulates the effect of synbiotics on the immunogenicity after SARS-COV-2 vaccination in elderly and diabetes patients.	Zhang L, Wang S, Wong MCS, Mok CKP, Ching JYL, Mak JWY, Chen C, Huo B, Yan S, Cheung CP, Chiu EOL, Fung EYT, Cheong PK, Chan FKL, Ng SC.	NPJ Biofilms Microbiomes	10.1038/s41522-025-00804-9	2025
	Efficacy in Clinical Studies of a Skin Care Serum Formula Containing 7 Short and Long Saccharides and Bacterial Fractions to Repair and Strengthen the Skin Barrier From Aggressions in Intense Conditions.	Pichon C, Mesrobian M, De Bussy S, Valverde E, Gueniche A.	J Cosmet Dermatol	10.1111/jocd.70193	2025
	Infant gut microbiome reprogramming following introduction of solid foods (weaning).	Ding M, Ross RP, Dempsey E, Li B, Stanton C.	Gut Microbes	10.1080/19490976.2025.2571428	2025
	Overview of the Efficacy of Using Probiotics for Neurosurgical and Potential Neurosurgical Patients.	Fijan S, Smigoc T.	Microorganisms	10.3390/microorganisms12071361	2024
	The gut microbiome and gastrointestinal cancers: mechanisms, biomarkers and therapeutic opportunities.	Makkar SK, Bishnupuri KS.	Front Physiol	10.3389/fphys.2025.1676796	2025
	Immunomodulatory Effects of Multi-Strain Probiotic Capsules for Psoriatic Arthritis: A Pilot Double-Blind Randomized Controlled Trial.	Alshihmani AHH, Kolahdooz H, Mahmoudi M, Rezaieyazdi Z, Kamal Kheder R, Tabasi NS, Fadaee A, Esmaeili SA.	Food Sci Nutr	10.1002/fsn3.71132	2025
	A randomized double-blind, placebo-controlled trial to evaluate the safety and efficacy of live Bifidobacterium longum CECT 7347 (ES1) and heat-treated Bifidobacterium longum CECT 7347 (HT-ES1) in participants with diarrhea-predominant irritable bowel syndrome.	Srivastava S, Basak U, Naghibi M, Vijayakumar V, Parihar R, Patel J, Jadon PS, Pandit A, Dargad RR, Khanna S, Kumar S, Day R.	Gut Microbes	10.1080/19490976.2024.2338322	2024
	Unique Athletic Gut Microbiomes and Their Role in Sports Performance: A Narrative Review.	Huminska-Lisowska K, Labaj PP, Zielinska K.	J Hum Kinet	10.5114/jhk/202642	2025
	Evaluation of Prebiotic Activity of Stellariae Radix Polysaccharides and Its Effects on Gut Microbiota.	Wang H, Li H, Li Z, Feng L, Peng L.	Nutrients	10.3390/nu15224843	2023
Genetics	Bifidobacterium longum and microbiome maturation modify a nutrient intervention for stunting in Zimbabwean infants.	Gough EK, Edens TJ, Carr L, Robertson RC, Mutasa K, Ntozini R, Chasekwa B, Geum HM, Baharmand I, Gill SK, Mutasa B, Mbuya MNN, Majo FD, Tavengwa N, Francis F, Tome J, Evans C, Kosek M, Prendergast AJ, Manges AR, Sanitation Hygiene Infant Nutrition Efficacy (SHINE) Trial Team.	EBioMedicine	10.1016/j.ebiom.2024.105362	2024
	Chinese expert consensus on the application of live combined Bifidobacterium, Lactobacillus, and Enterococcus powder/capsule in digestive system diseases (2021).	Fang J, Yang Y, Xie W.	J Gastroenterol Hepatol	10.1111/jgh.16195	2023
	Gut Microbiota in Adults with Chronic Widespread Pain: A Systematic Review.	Leong PY, Shi LH.	Diseases	10.3390/diseases13090299	2025
	Bile salt hydrolase catalyses formation of amine-conjugated bile acids.	Rimal B, Collins SL, Tanes CE, Rocha ER, Granda MA, Solanki S, Hoque NJ, Gentry EC, Koo I, Reilly ER, Hao F, Paudel D, Singh V, Singh V, Yan T, Kim MS, Bittinger K, Zackular JP, Krausz KW, Desai D, Amin S, Coleman JP, Shah YM, Bisanz JE, Gonzalez FJ, Vanden Heuvel JP, Wu GD, Zemel BS, Dorrestein PC, Weinert EE, Patterson AD.	Nature	10.1038/s41586-023-06990-w	2024
	Promoter engineering for efficient production of sucrose phosphorylase in Bacillus subtilis and its application in enzymatic synthesis of 2-O-alpha-D-glucopyranosyl-L-ascorbic acid.	Gan T, Fang J, Wang Y, Liu K, Sang Y, Chen H, Lu Y, Zhu L, Chen X.	Enzyme Microb Technol	10.1016/j.enzmictec.2023.110267	2023
Metabolism	Identification of Gut Microbiome Signatures Associated with Serotonin Pathway in Tryptophan Metabolism of Patients Undergoing Hemodialysis.	Kuo TH, Wu PH, Liu PY, Chuang YS, Tai CJ, Kuo MC, Chiu YW, Lin YT.	Int J Mol Sci	10.3390/ijms262110463	2025
Genetics	Integrative genomic reconstruction reveals heterogeneity in carbohydrate utilization across human gut bifidobacteria.	Arzamasov AA, Rodionov DA, Hibberd MC, Guruge JL, Kent JE, Kazanov MD, Leyn SA, Elane ML, Sejane K, Furst A, Bode L, Barratt MJ, Gordon JI, Osterman AL.	Nat Microbiol	10.1038/s41564-025-02056-x	2025
	Efficient Production of 2-O-alpha-D-Glucosyl Glycerol Catalyzed by an Engineered Sucrose Phosphorylase from Bifidobacterium longum.	Lei J, Tang K, Zhang T, Li Y, Gao Z, Jia H.	Appl Biochem Biotechnol	10.1007/s12010-022-03939-z	2022
	Efficacy of probiotics as adjuvant therapy in bronchial asthma: a systematic review and meta-analysis.	Balan D, Baral T, Manu MK, Mohapatra AK, Miraj SS.	Allergy Asthma Clin Immunol	10.1186/s13223-024-00922-7	2024
	Respiratory diseases and the gut microbiota: an updated review.	Yu X, Yu X, Wang Y, Guo X, Wang C, Wang F.	Front Cell Infect Microbiol	10.3389/fcimb.2025.1629005	2025
	Female genital tract microbiome: the influence of probiotics on assisted reproduction.	Santana ASA, Povoa AM.	Rev Bras Ginecol Obstet	10.61622/rbgo/2024rbgo82	2024
	Structural changes of polysaccharides from Astragulus after honey processing and their bioactivities on human gut microbiota.	Tian Y, Wu J, Zheng Y, Li M, Xu X, Chen H, Rui W.	J Sci Food Agric	10.1002/jsfa.12808	2023
Metabolism	A Low-Gluten Diet Reduces the Abundance of Potentially Beneficial Bacteria in Healthy Adult Gut Microbiota	Delmas E, Bingula R, Del'homme C, Meunier N, Caille A, Lyon-Belgy N, Richard R, Do Couto M, Wittrant Y, Bernalier-Donadille A.	Nutrients		2025
	A review on the potential use of eubiotics in non-chicken poultry species.	Mnisi CM, Njeri FM, Maina AN, Waliaula PK, Cheng V, Kumalo I, Egbu CF, Kiarie EG.	Trop Anim Health Prod	10.1007/s11250-025-04466-9	2025
	Identification of gamma-Glutamyl-Selenomethionine as the Principal Selenium Metabolite in a Selenium-Enriched Probiotic, Bifidobacterium longum, by Two-Dimensional HPLC-ICP MS and HPLC-ESI Orbitrap MS.	Zhu H, Bierla K, Jin X, Szpunar J, Chen D, Lobinski R.	J Agric Food Chem	10.1021/acs.jafc.2c01409	2022
Transcriptome	Comprehensive gene expression analysis of organoid-derived healthy human colonic epithelium and cancer cell line stimulated with live probiotic bacteria.	Sen A, Imai A, Miyauchi E, Yanagisawa K, Oda T, Sasaki F, Uchida S, Okada T, Yokobori T, Saeki H, Odamaki T, Sasaki N.	Sci Rep	10.1038/s41598-025-07391-x	2025
	The impact of antimicrobial food additives and sweeteners on the growth and metabolite production of gut bacteria.	de Souza Lopes A, Elisabete Costa Antunes A, Idelca Aires Machado K, Sartoratto A, Cristina Teixeira Duarte M.	Folia Microbiol (Praha)	10.1007/s12223-023-01076-6	2023
	Bifidobacterium longum NSP001-derived extracellular vesicles ameliorate ulcerative colitis by modulating T cell responses in gut microbiota-(in)dependent manners.	Nie X, Li Q, Ji H, Zhang S, Wang Y, Xie J, Nie S.	NPJ Biofilms Microbiomes	10.1038/s41522-025-00663-4	2025
	Bi-Directional Relationship Between Bile Acids (BAs) and Gut Microbiota (GM): UDCA/TUDCA, Probiotics, and Dietary Interventions in Elderly People.	Francini E, Badillo Pazmay GV, Fumarola S, Procopio AD, Olivieri F, Marchegiani F.	Int J Mol Sci	10.3390/ijms26041759	2025
	The Role of Gut Microbiota in Orthopedic Surgery: A Systematic Review.	Nadeem-Tariq A, Kazemeini S, Michelberger M, Fang C, Maitra S, Nelson K.	Microorganisms	10.3390/microorganisms13051048	2025
	Effects of Viable and Heat-Inactivated Bifidobacterium longum D42 on Proliferation and Apoptosis of HT-29 Human Colon Cancer Cells.	Zhang Y, Cao T, Wang Y, Yang R, Han Y, Li S, Liu D, Yue Y, Cao Y, Li B, Wang S, Huo G.	Foods	10.3390/foods13060958	2024
	Intestinal microecological transplantation for a patient with chronic radiation enteritis: A case report.	Wang L, Li Y, Zhang YJ, Peng LH.	World J Gastroenterol	10.3748/wjg.v30.i19.2603	2024
	Composition of the intestinal microbiota of infant rhesus macaques at different ages before and after weaning	Li Y, Wang J, Liu Q, Yang F, Chen L, Xu H, Jin W, Liu Y, Zhang W, Yang F, He Z, Zhao Y.	Heliyon.		2023
	Bifidobacterium longum and Chlorella sorokiniana Combination Modulates IFN-gamma, IL-10, and SOCS3 in Rotavirus-Infected Cells.	Velderrain-Armenta F, Gonzalez-Ochoa G, Tamez-Guerra P, Romero-Arguelles R, Romo-Saenz CI, Gomez-Flores R, Flores-Mendoza L, Icedo-Garcia R, Sonanez-Organis JG.	Int J Mol Sci	10.3390/ijms25105514	2024
Pathogenicity	Effect of Postbiotic Bifidobacterium longum CECT 7347 on Gastrointestinal Symptoms, Serum Biochemistry, and Intestinal Microbiota in Healthy Adults: A Randomised, Parallel, Double-Blind, Placebo-Controlled Pilot Study.	Naghibi M, Pont-Beltran A, Lamelas A, Llobregat L, Martinez-Blanch JF, Rojas A, Alvarez B, Lopez Plaza B, Arcos Castellanos L, Chenoll E, Vijayakumar V, Day R.	Nutrients	10.3390/nu16223952	2024
Pathogenicity	Probiotic Supplementation and Inflammatory Status in Coronary Artery Disease: A Systematic Review and Meta-Analysis.	Chiou YY, Chiu TY, Chen MJ.	Microorganisms	10.3390/microorganisms13102303	2025
	Improved gut microbiota by selenium-enriched Bifidobacterium longum DD98 alleviates chemotherapy-induced intestinal mucositis via inhibiting the STING pathway.	Qiu YS, Ye C, Li Q, Jiang LC, Zhou CC, Fu H, Li DJ, Chen D, Shen FM.	NPJ Sci Food	10.1038/s41538-025-00473-0	2025
	Probiotics as technological innovations in psychiatric disorders: patents and research reviews.	de Lima AA, Santos SS, de Araujo MA, Vinderola G, Villarreal CF, Viana MDM.	Front Nutr	10.3389/fnut.2025.1567097	2025
	Biosorption of cadmium from aqueous solution by combination of microorganisms and chitosan: response surface methodology for optimization of removal conditions.	Khanniri E, Yousefi M, Mortazavian AM, Khorshidian N, Sohrabvandi S, Koushki MR, Esmaeili S.	J Environ Sci Health A Tox Hazard Subst Environ Eng	10.1080/10934529.2023.2188023	2023
	Therapeutic effects of three-strain probiotic combination on slow transit constipation: mechanistic insights into MAPK signaling pathway and gut microbiota restoration.	Liu L, Li P, Chen Y, Yang G, Cheng Y, Liu S, Zhang X, Wu Y, Liu Q, Zhao P, Fang W, Ren Y, Hu L, Liu Y, Li K, Chen Z, Ke X, Li Q, Shen A.	Front Pharmacol	10.3389/fphar.2025.1684442	2025
	Comparative Study of Prebiotics for Infants Using a Fecal Culture System: Insights into Responders and Non-Responders.	Mingat SX, Ehara T, Nakamura H, Miyaji K.	Nutrients	10.3390/nu16193347	2024
	Long-term efficacy of dapagliflozin combined with Bifidobacterium triple viable tablets on metabolic syndrome and gut microbiota in overweight/obese patients with type 2 diabetes.	Li K, Li Z, Liu L.	Endocr Connect	10.1530/ec-25-0219	2025
	Mitigation of chemotherapy-induced gut dysbiosis and diarrhea by supplementation with heat-killed Bacteroides fragilis.	Yan X, Lin X, Wu J, Zheng L, Liu Y, Wu F, Lin Y, Lu Y, Huang C, Shen B, Liu H, Huang R, Hou F, Zhou Q, Song M, Liu K, Zhu F, Li S, Lin Y, Wang W, Li P, Liao W, Zhi F.	BMC Med	10.1186/s12916-025-04233-5	2025
	The Athlete Gut Microbiome: A Narrative Review of Multi-Omics Insights and Next-Generation Probiotic Strategies.	Li Z, Li Y, Wang Y, Chen J, Liu Y.	Nutrients	10.3390/nu17203260	2025
	Bifidobacterium longum CCFM752 prevented hypertension and aortic lesion, improved antioxidative ability, and regulated the gut microbiome in spontaneously hypertensive rats.	Lu W, Wang Y, Fang Z, Wang H, Zhu J, Zhai Q, Zhao J, Zhang H, Chen W, Chen W.	Food Funct	10.1039/d1fo04446j	2022
	Understanding the interaction between melatonin and bifidobacteria.	Rizzo SM, Longhi G, Tarracchini C, Argentini C, Viappiani A, Bianchi MG, Bussolati O, van Sinderen D, Ventura M, Turroni F.	Microbiome Res Rep	10.20517/mrr.2025.10	2025
	Bifidobacterium and Lactobacillus improve inflammatory bowel disease in zebrafish of different ages by regulating the intestinal mucosal barrier and microbiota.	Ni Y, Zhang Y, Zheng L, Rong N, Yang Y, Gong P, Yang Y, Siwu X, Zhang C, Zhu L, Fu Z.	Life Sci	10.1016/j.lfs.2023.121699	2023
	Probiotics for pediatric diarrhea and constipation: an umbrella meta-analysis.	Chen L, Wang Y, Liu X, Wong H, Huang C.	BMC Pediatr	10.1186/s12887-025-06002-y	2025
	Single Strain vs Multiple Strain Probiotics: The Clinician's Choice.	Kesavelu D, Yadav Krishnamurty A, A P.	Cureus	10.7759/cureus.86353	2025
Pathogenicity	Gut mucin fucosylation dictates the entry of botulinum toxin complexes.	Amatsu S, Matsumura T, Morimoto C, Keisham S, Goto Y, Kohda T, Hirabayashi J, Kitadokoro K, Katayama T, Kiyono H, Tateno H, Zuka M, Fujinaga Y.	Nat Commun	10.1038/s41467-025-65384-w	2025
	Efficacy of probiotic, prebiotic, and synbiotics supplements in individuals with anemia: a systematic review and meta-analysis of randomized controlled trials.	Hu Q, Liu Y, Fei Y, Zhang J, Yin S, Zou H, Zhu F.	BMC Gastroenterol	10.1186/s12876-024-03562-8	2024
	Dietary of Lactobacillus paracasei and Bifidobacterium longum improve nonspecific immune responses, growth performance, and resistance against Vibrio parahaemolyticus in Penaeus vannamei.	Huang HT, Hu YF, Lee BH, Huang CY, Lin YR, Huang SN, Chen YY, Chang JJ, Nan FH.	Fish Shellfish Immunol	10.1016/j.fsi.2022.07.062	2022
	Maternal Milk Orchestrates the Development of Infant Gut Microbiota: Implications for Health and Future Research Directions.	Wang R, Sun S, Zhang Q, Wu G, Ren F, Chen J.	Research (Wash D C)	10.34133/research.0558	2025
	Probiotics in the management of radiation-induced oral mucositis.	Li Y, Li Z, Zheng S, Xu X.	Front Cell Infect Microbiol	10.3389/fcimb.2024.1477143	2024
	A Bifidobacterium Strain with Antibacterial Activity, Its Antibacterial Characteristics and In Vitro Probiotics Studies.	Ji J, Li T, Ma B, Wang R.	Microorganisms	10.3390/microorganisms13061190	2025
	A Novel Bifidobacterium longum ssp. longum Strain with Pleiotropic Effects.	Ratsep M, Kilk K, Zilmer M, Kuus L, Songisepp E.	Microorganisms	10.3390/microorganisms12010174	2024
Pathogenicity	Exploring the Potential of Novel Animal-Origin Probiotics as Key Players in One Health: Opportunities and Challenges.	Gorzelanna Z, Mamrot A, Bedkowska D, Bubak J, Miszczak M.	Int J Mol Sci	10.3390/ijms26115143	2025
	Cutaneous UVB Irradiation Alters Gut Microbiota Independently of Skin Inflammation in SKH-1 Hairless Mice.	Lee E, Sim WJ, Lim TG.	J Microbiol Biotechnol	10.4014/jmb.2507.07020	2025
	Causal relationships between gut microbiome and obstructive sleep apnea: a bi-directional Mendelian randomization.	Liu L, He G, Yu R, Lin B, Lin L, Wei R, Zhu Z, Xu Y.	Front Microbiol	10.3389/fmicb.2024.1410624	2024
	The Role of Gut Microbiota Modification in Nonalcoholic Fatty Liver Disease Treatment Strategies.	Yaghmaei H, Bahanesteh A, Soltanipur M, Takaloo S, Rezaei M, Siadat SD.	Int J Hepatol	10.1155/2024/4183880	2024
	A methyl esterase from Bifidobacterium longum subsp. longum reshapes the prebiotic properties of apple pectin by triggering differential modulatory capacity in faecal cultures.	Calvete-Torre I, Sabater C, Munoz-Almagro N, Campelo AB, Moreno FJ, Margolles A, Ruiz L.	Microb Biotechnol	10.1111/1751-7915.14443	2024
	Activation of chloride channels and promotion of bowel movements by heat-killed Bifidobacterium longum CLA8013.	Makizaki Y, Kishimoto M, Tanaka Y, Ohno H.	Biosci Microbiota Food Health	10.12938/bmfh.2023-084	2024
	In vitro fermentation of human milk oligosaccharides by individual Bifidobacterium longum-dominant infant fecal inocula.	Li H, Lane JA, Chen J, Lu Z, Wang H, Dhital S, Fu X, Huang Q, Liu F, Zhang B.	Carbohydr Polym	10.1016/j.carbpol.2022.119322	2022
	Engineering Bifidobacterium longum Endo-alpha-N-acetylgalactosaminidase for Neu5Acalpha2-3Galbeta1-3GalNAc reactivity on Fetuin.	Hansen DK, Hansen AL, Koivisto JM, Shuoker B, Abou Hachem M, Winther JR, Willemoes M.	Arch Biochem Biophys	10.1016/j.abb.2022.109280	2022
	Cholesterol-Lowering Mechanism of Lactobacillus Bile Salt Hydrolase Through Regulation of Bifidobacterium pseudolongum in the Gut Microbiota.	Liu Y, Kuang W, Li M, Wang Z, Liu Y, Zhao M, Huan H, Yang Y.	Nutrients	10.3390/nu17183019	2025
	Bifidobacterium longum RAPO Attenuates Dermal and Pulmonary Fibrosis in a Mouse Model of Systemic Sclerosis through Macrophage Modulation and Growth of Short-Chain Fatty Acid Producers.	Park HJ, Yu D, Hong ST, Lee J, Park SJ, Park MS, Lee H, Kim M, Cheon YH, Lee SG, Sohn DH, Jun JB, Kim S, Lee SI.	Immune Netw	10.4110/in.2024.24.e41	2024
	Utilizing Xanthan Gum Coatings as Probiotic Bacteria Carriers to Enhance Postharvest Quality and Antioxidants in Fresh-Cut Cantaloupe and Honeydew (Cucumis melo L.) Melons.	Chikhala T, Seke F, Slabbert RM, Sultanbawa Y, Sivakumar D.	Foods	10.3390/foods13060940	2024
	Bifidobacterium longum SX-1326 ameliorates gastrointestinal toxicity after irinotecan chemotherapy via modulating the P53 signaling pathway and brain-gut axis.	Yue F, Zeng X, Wang Y, Fang Y, Yue M, Zhao X, Zhu R, Zeng Q, Wei J, Chen T.	BMC Microbiol	10.1186/s12866-023-03152-w	2024
Genetics	Genomic insights into the beneficial potential of Bifidobacterium and Enterococcus strains isolated from Cameroonian infants.	Kaktcham PM, Kujawska M, Kouam EMF, Piame LT, Tientcheu MLT, Mueller J, Felsl A, Truppel BA, Ngoufack FZ, Hall LJ.	Microb Genom	10.1099/mgen.0.001354	2025
	Improvement of the functional properties of insoluble dietary fiber from corn bran by ultrasonic-microwave synergistic modification.	Jiang C, Zeng X, Wei X, Liu X, Wang J, Zheng X.	Ultrason Sonochem	10.1016/j.ultsonch.2024.106817	2024
	Efficacy of Probiotic Tablets in the Reduction of Halitosis: A Randomised, Single Blind, Controlled Clinical Trial.	Huang G, Li N.	Oral Health Prev Dent	10.3290/j.ohpd.b5866901	2024
	Fermentation and Quality Characteristics of Yogurt Treated with Bifidobacterium longum.	Son JK, Jo YJ, Jung YJ, Lee YR, Lee J, Jeong HS.	Nutrients	10.3390/nu15153490	2023
Phylogeny	Faecal microbiota composition is related to response to CDK4/6-inhibitors in metastatic breast cancer: A prospective cross-sectional exploratory study.	Schettini F, Fontana A, Gattazzo F, Strina C, Milani M, Cappelletti MR, Cervoni V, Morelli L, Curigliano G, Iebba V, Generali D.	Eur J Cancer	10.1016/j.ejca.2023.112948	2023
	Perinatal factors influencing the earliest establishment of the infant microbiome.	Linehan K, Healy K, Hurley E, O'Shea CA, Ryan CA, Ross RP, Stanton C, Dempsey EM.	Microbiome Res Rep	10.20517/mrr.2024.92	2025
	Unlocking Probiotic Potential: Physicochemical Approaches to Evaluate Probiotic Bacterial Adhesion Potential to the Intestinal Tract.	Phung TT, Dupont S, Beney L, Chanut J, Karbowiak T.	Mol Nutr Food Res	10.1002/mnfr.202400705	2025
Transcriptome	Combined Analysis of Transcriptomes and Metabolomes Reveals Key Genes and Substances That Affect the Formation of a Multi-Species Biofilm by Nine Gut Bacteria.	Zhang T, Pei Z, Wang H, Zhao J, Chen W, Lu W.	Microorganisms	10.3390/microorganisms13020234	2025
	Bifidobacterium longum relieves constipation by regulating the intestinal barrier of mice.	Wang L, Chai M, Wang J, Yu Q, Wang G, Zhang H, Zhao J, Chen W, Chen W.	Food Funct	10.1039/d1fo04151g	2022
	Pre-sleep casein ingestion with probiotic strains improves anaerobic power and lower-body-specific strength and power performance in soccer players.	Sadeghi R, Hemmatinafar M, Eftekhari F, Imanian B, Koureshfard N.	J Int Soc Sports Nutr	10.1080/15502783.2025.2505184	2025
	In Vitro Probiotic Modulation of Specific Dietary Complex Sugar Consumption in Fecal Cultures in Infants.	Mollova D, Baev V, Iliev I.	Microorganisms	10.3390/microorganisms13102352	2025
	The Role and Mechanisms of Probiotic Supplementation on Depressive Symptoms: A Narrative Review.	Dacaya P, Sarapis K, Moschonis G.	Curr Nutr Rep	10.1007/s13668-025-00644-1	2025
	Gut Bifidobacterium longum is associated with better native liver survival in patients with biliary atresia.	Lee CS, Lin CR, Chua HH, Wu JF, Chang KC, Ni YH, Chang MH, Chen HL.	JHEP Rep	10.1016/j.jhepr.2024.101090	2024
	Evaluation of Faecal Microbiota Following Probiotics in Infants of Mothers with Gestational Diabetes Mellitus Trial: Protocol for Double-Blind Placebo-Controlled Randomized Trial.	Athalye-Jape G, Rath CP, Panchal H, Mishra A, Graham D, Patole S.	Microorganisms	10.3390/microorganisms13010112	2025
	Contribution of the capsular polysaccharide layer to antibiotic resistance in bifidobacteria.	Argentini C, Tarracchini C, Alessandri G, Longhi G, Milani C, van Sinderen D, Ventura M, Turroni F.	FEMS Microbiol Ecol	10.1093/femsec/fiad032	2023
	Daily Supplementation with Bifidobacterium longum KACC91563 Alleviates Allergic Contact Dermatitis in an Animal Model.	Hoa VB, Park SH, Ha DH, Son JH, Lee KH, Park WS, Yoo JY, Bae IS, Kim HW, Kang HB, Lee SM, Ham JS.	Foods	10.3390/foods13142190	2024
	Functional Characterization of Endo- and Exo-Hydrolase Genes in Arabinan Degradation Gene Cluster of Bifidobacterium longum subsp. suis.	Kang Y, Choi CY, Kang J, Ju YR, Kim HB, Han NS, Kim TJ.	Int J Mol Sci	10.3390/ijms25063175	2024
	A Systematic Review of the Effects of Probiotics and Synbiotics on Infection Incidence after Liver Transplant Surgery.	Alhouei B, Eslamian G, Mohtadi M.	Prev Nutr Food Sci	10.3746/pnf.2025.30.2.101	2025
Genetics	The Genome of Bifidobacterium longum subsp. infantis YLGB-1496 Provides Insights into Its Carbohydrate Utilization and Genetic Stability.	Li X, Yang J, Shi S, Lan H, Zhao W, Hung W, He J, Wang R.	Genes (Basel)	10.3390/genes15040466	2024
	Validation of the hypothesis on the protective role of functional beverages in mitigating the adverse health effects of digital technologies.	Tultabayev M, Zhumanova U, Tultabayeva T, Shoman A.	Front Nutr	10.3389/fnut.2025.1626046	2025
	Gut microbiota indole-3-propionic acid mediates neuroprotective effect of probiotic consumption in healthy elderly: A randomized, double-blind, placebo-controlled, multicenter trial and in vitro study.	Kim CS, Jung S, Hwang GS, Shin DM.	Clin Nutr	10.1016/j.clnu.2023.04.001	2023
	Use of Probiotics for Preventing Necrotizing Enterocolitis in Preterm Infants: A Survey of Current Practices Among Indian Neonatologists.	More K, Hanumantharaju A, Amrit A, Nimbalkar SM, Patole S.	Cureus	10.7759/cureus.73923	2024
Phylogeny	Comparative analysis of oral microbiome in saliva samples of oral leukoplakia, proliferative leukoplakia and oral squamous cell carcinoma.	Intini R, Balsells S, Bagan L, Fortuna G, Sroussi H, Bagan J.	Front Oral Health	10.3389/froh.2025.1600090	2025
	Tumor-suppressing multi-enterobacteria and PD-1/PD-L1 immune checkpoint inhibitor combination improves the outcome of hepatocellular carcinoma therapy	Wu D, Fan Y, Zhang M, Wang X, He X, Guo X, Liu Y, Cao C, Deng Z.	Front Immunol		2025
	The Role of Gut Microbiota in Pediatric Obesity and Metabolic Disorders: Insights from a Comprehensive Review.	Koller AM, Sasaran MO, Marginean CO.	Nutrients	10.3390/nu17111883	2025
	Gut-brain-liver axis in growth hormone deficiency: role of microbiota-derived short-chain fatty acids in ethnic variability and therapeutic development.	Meng D, Kong W, Cheng S, Liu H, Huang C.	Front Public Health	10.3389/fpubh.2025.1541654	2025
Metabolism	Association of gut microbiota and glucose metabolism in children with disparate degrees of adiposity.	Yuan X, Zhang Y, Lin X, Yang X, Chen R.	Pediatr Obes	10.1111/ijpo.13009	2023
Metabolism	Adverse effects of titanium dioxide nanoparticles on beneficial gut bacteria and host health based on untargeted metabolomics analysis.	Wu Y, Cao X, Du H, Guo X, Han Y, McClements DJ, Decker E, Xing B, Xiao H.	Environ Res	10.1016/j.envres.2023.115921	2023
Metabolism	Ameliorating Effects of Bifidobacterium longum subsp. infantis FB3-14 against High-Fat-Diet-Induced Obesity and Gut Microbiota Disorder.	Kou R, Wang J, Li A, Wang Y, Zhang B, Liu J, Sun Y, Wang S.	Nutrients	10.3390/nu15194104	2023
	The gut microbiota in persistent post-operative pain following breast cancer surgery.	Masaud K, Collins JM, Rubio RC, Corrigan M, Cotter PD, O'Brien N, Bluett R, Jimenez CK, O'Mahony SM, Shorten GD.	Sci Rep	10.1038/s41598-024-62397-1	2024
	Viability of Probiotics, Rheological and the Sensorial Properties of Probiotic Yogurts Fortified with Aqueous Extracts of Some Plants.	Akan E, Yerlikaya O, Bayram OY, Kinik O.	An Acad Bras Cienc	10.1590/0001-3765202220211274	2022
	A core human gut microbe, Mediterraneibacter gnavus, produces a broad-spectrum bacteriocin mediterrocin.	Mingolelli G, Raherisoanjato J, Trinh D, Gao Y, Henke M.	mBio	10.1128/mbio.01523-25	2025
	In vitro intestinal simulation system on the carbon source utilization characteristics and mechanism of interspecific syntrophic effects of Bifidobacterium longum CECT7894 and Pediococcus pentosaceus CECT8330.	Li J, Xu L, Liao J, Li X, Wang X, Wu Q, Zhu L.	Front Pediatr	10.3389/fped.2023.1276846	2023
	Microencapsulation of Bifidobacterium longum 51A cells by spray drying and its incorporation in acerola (Malpighia emarginata) pulp powder	Costa K, Silva LS, Kobori CN, da Silva AM, Nicoli JR.	International journal of food science and technology.		2022
	Nutritional, antioxidant, and antimicrobial assessment of carrot powder and its application as a functional ingredient in probiotic soft cheese.	Kamel DG, Hammam ARA, Nagm El-Diin MAH, Awasti N, Abdel-Rahman AM.	J Dairy Sci	10.3168/jds.2022-22090	2023
	Heat-killed Bifidobacterium longum BBMN68 and inulin protect against high-fat diet-induced obesity by modulating gut microbiota.	Sun S, Zhang Q, Li D, Li H, Ma H, Wu X, Li Y, Wang P, Liu R, Feng H, Zhang Y, Sang Y, Fang B, Wang R.	Front Nutr	10.3389/fnut.2024.1406070	2024
	Gut microbiota associated with equol production in school-age children.	Wada K, Suda W, Ueno T, Masuoka H, Yamakawa M, Nakashima Y, Sugino M, Mori T, Uchiyama S, Sumoto Y, Kiguchi Y, Hattori M, Nagata C.	Eur J Nutr	10.1007/s00394-025-03625-w	2025
Phylogeny	BN-BacArena: Bayesian network extension of BacArena for the dynamic simulation of microbial communities.	Blasco T, Balzerani F, Valcarcel LV, Larranaga P, Bielza C, Francino MP, Rufian-Henares JA, Planes FJ, Perez-Burillo S.	Bioinformatics	10.1093/bioinformatics/btae266	2024
	The Efficacy of Probiotics Supplementation on the Quality of Life of Patients with Gastrointestinal Disease: A Systematic Review of Clinical Studies.	Moludi J, Saber A, Zozani MA, Moradi S, Azamian Y, Hajiahmadi S, Pasdar Y, Moradi F.	Prev Nutr Food Sci	10.3746/pnf.2024.29.3.237	2024
	Breastfeeding and the milk resistome shape the establishment and transmission of antibiotic resistance genes in the infant gut microbiome.	Pan Z, Walsh CJ, Feehily C, Nori SRC, McAuliffe FM, Cotter PD, MacSharry J, van Sinderen D.	Gut Microbes	10.1080/19490976.2025.2541033	2025
	Effects of Bifidobacterium longum BB536 and Bifidobacterium breve MCC1274 on Body Composition in Normal and Overweight Adults in Randomized Placebo-Controlled Study.	Sato S, Arai S, Kato K, Yoshida K, Iwabuchi N, Sagami T, Tanaka M.	Nutrients	10.3390/nu16060815	2024
	Prebiotic potential and metabolic benefits of Acorus gramineus rhizome-derived polysaccharides in a high-fat diet-induced obesity model.	Park M, Chae YR, Lee HB, Lee JE, Lee YR, Hur J, Park HY.	Front Nutr	10.3389/fnut.2025.1605201	2025
	Gut microbiota in patients with sarcopenia: a systematic review and meta-analysis.	Wang G, Li Y, Liu H, Yu X.	Front Microbiol	10.3389/fmicb.2025.1513253	2025
	Extraction, Characterization, Biological Properties, and X-Ray Fluorescence Analysis of Functional Polysaccharides Derived from Limnospira platensis	Pan-utai W, Phomkaivon N, Settachaimongkon S, Pongponpai P, Songsiriritthigul C.	Life (Basel)		2025
	Lacticaseibacillus rhamnosus LRa05 in the treatment of acute diarrhea in children: a randomized controlled trial.	Chen K, Zeng K, Jin S, Ma Y, Cai L, Xu P, Nie Y, Luo L, Yu Q, Liu C.	Front Nutr	10.3389/fnut.2024.1479186	2024
	Gut microbial features may influence antiviral IgG levels after vaccination against viral respiratory infectious diseases: the evidence from two-sample bidirectional mendelian randomization.	Tu J, Wang Y, Ye X, Wang Y, Zou Y, Jia L, Yang S, Yu R, Liu W, Huang P.	BMC Infect Dis	10.1186/s12879-024-09189-0	2024
	Interventions targeting the gut microbiota and their possible effect on gastrointestinal and neurobehavioral symptoms in autism spectrum disorder.	Takyi E, Nirmalkar K, Adams J, Krajmalnik-Brown R.	Gut Microbes	10.1080/19490976.2025.2499580	2025
Pathogenicity	"Do probiotics mitigate GI-induced inflammation and perceived fatigue in athletes? A systematic review".	Kearns RP, Dooley JSG, Matthews M, McNeilly AM.	J Int Soc Sports Nutr	10.1080/15502783.2024.2388085	2024
	Teenagers with Obesity at the Gym: Recommendations for Physical Activity, Diet, and Supplementation-A Narrative Review.	Koziol-Kozakowska A, Wojcik M, Mazur-Kurach P, Drozdz D, Brzek A.	Nutrients	10.3390/nu17111798	2025
	Probiotics in the Prophylaxis of Premature Rupture of Membranes and Cervical Incompetence.	Vaduva CC, Petrescu AM, Dira LM, Ruican D, Pana RC.	Nutrients	10.3390/nu16234230	2024
	The effect of psychoactive bacteria, Bifidobacterium longum Rosell®-175 and Lactobacillus rhamnosus JB-1, on brain proteome profiles in mice.	Jarosz LS, Socala K, Michalak K, Wiater A, Ciszewski A, Majewska M, Marek A, Gradzki Z, Wlaz P.	Psychopharmacology (Berl)	10.1007/s00213-023-06519-z	2024
Genetics	Gut-Microbiome Signatures Predicting Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer: A Systematic Review.	Domilescu I, Miutescu B, Horhat FG, Popescu A, Nica C, Ghiuchici AM, Gadour E, Sirbu I, Hutanu D.	Metabolites	10.3390/metabo15060412	2025
Biotechnology	In vitro digestive system simulation and anticancer activity of soymilk fermented by probiotics and synbiotics immobilised on agro-industrial residues.	Gad AI, Orabi MM, Abou-Taleb KA, Abdelghani DY, Amin SA.	Sci Rep	10.1038/s41598-024-68086-3	2024
	Network meta-analysis of randomized control trials evaluating the effectiveness of various probiotic formulations in patients with type 2 diabetes mellitus.	Allam AR, Helal MB, Alhateem MS, Shehab MA, Elshaar AG, Saeda MA, Ibrahim FM, Khalil AM, Mahmoud AM.	Diabetol Metab Syndr	10.1186/s13098-025-01841-2	2025
	Longitudinal quantification of Bifidobacterium longum subsp. infantis reveals late colonization in the infant gut independent of maternal milk HMO composition.	Ennis D, Shmorak S, Jantscher-Krenn E, Yassour M.	Nat Commun	10.1038/s41467-024-45209-y	2024
Phylogeny	Comparison of Gut Microbiomes Between Neonates Born by Cesarean Section and Vaginal Delivery: Prospective Observational Study.	Pahirah N, Narkwichean A, Taweechotipatr M, Wannaiampikul S, Duang-Udom C, Laosooksathit W.	Biomed Res Int	10.1155/bmri/8302361	2024
	Behavior study of Bifidobacterium longum using solid state fermentation from commercial soybean meal	Rodriguez de Olmos A, Garro OA, Garro MS.	Lebensm Wiss Technol	10.1016/j.lwt.2022.113101	2022
	Investigation of Effects of Novel Bifidobacterium longum ssp. longum on Gastrointestinal Microbiota and Blood Serum Parameters in a Conventional Mouse Model.	Ratsep M, Kilk K, Zilmer M, Kuusik S, Kuus L, Vallas M, Gerulis O, Stsepetova J, Orav A, Songisepp E.	Microorganisms	10.3390/microorganisms12040840	2024
	Both viable Bifidobacterium longum subsp. infantis B8762 and heat-killed cells alleviate the intestinal inflammation of DSS-induced IBD rats.	Li Z, Peng C, Sun Y, Zhang T, Feng C, Zhang W, Huang T, Yao G, Zhang H, He Q.	Microbiol Spectr	10.1128/spectrum.03509-23	2024
Pathogenicity	The Anti-Inflammatory, Immunomodulatory, and Pro-Autophagy Activities of Probiotics for Colorectal Cancer Prevention and Treatment: A Narrative Review.	Garavaglia B, Vallino L, Ferraresi A, Visciglia A, Amoruso A, Pane M, Munteanu C, Isidoro C.	Biomedicines	10.3390/biomedicines13071554	2025
	Effects of meglumine antimoniate and allopurinol treatment on the fecal microbiome profile in dogs with leishmaniosis.	Marti-Carreras J, Carrasco M, Noguera-Julian M, Francino O, Leal RO, Ferrer L, Oliva G, Molina J, Roura X.	Anim Microbiome	10.1186/s42523-025-00447-3	2025
	The effect of probiotic-fortified kefir on cardiovascular risk factors in elderly population: a double-blind, randomized, placebo-controlled clinical trial.	Noori M, Shateri Z, Babajafari S, Eskandari MH, Parastouei K, Ghasemi M, Afshari H, Samadi M.	BMC Nutr	10.1186/s40795-024-00875-5	2024
	Microbiota-Gut-Brain Axis Dysregulation in Alzheimer's Disease: Multi-Pathway Effects and Therapeutic Potential.	Qu L, Li Y, Liu F, Fang Y, He J, Ma J, Xu T, Wang L, Lei P, Dong H, Jin L, Yang Q, Wu W, Sun D.	Aging Dis	10.14336/ad.2023.0823-2	2024
Metabolism	Modulation of Intestinal Smooth Muscle Cell Function by BL-99 Postbiotics in Functional Constipation.	Zhao W, Liu M, Lan H, Wang R, Hung WL, He J, Fang B.	Foods	10.3390/foods14193441	2025
	A Mini Literature Review of Probiotics: Transforming Gastrointestinal Health Through Evidence-Based Insights.	Mohammed C, Fuego JP, Garcia KV, Jamil H, Rajesh RY, Escobar AS, Hassan MJ, Rai M.	Cureus	10.7759/cureus.57055	2024
	Evaluation of treatment in acute gastroenteritis: A comparative study.	Yalcin G, Demirbas F, Bacalan F, Toy EB.	J Pak Med Assoc	10.47391/jpma.4438	2022
	Potentially probiotic Limosilactobacillus reuteri from human milk strengthens the gut barrier in T84 cells and a murine enteroid model.	Anjum J, Quach A, Wongkrasant P, Nazir S, Tariq M, Barrett KE, Zaidi A.	J Appl Microbiol	10.1093/jambio/lxac029	2023
	'It takes a village': deciphering the role of the gut microbiome in the health and performance of military personnel.	Templeman I, Parish E, Rimmer J, Clarke G, Troth T, Goodson MS, Soares JW, Harding SV.	BMJ Mil Health	10.1136/military-2024-002746	2025
	Effects of probiotic supplementation on 12 min run performance, mood management, body composition and gut microbiota in amateur marathon runners: A double-blind controlled trial.	Wang L, Meng FJ, Jin YH, Wu LQ, Tang RY, Xu KH, Guo Y, Mao JJ, Ding JP, Li J.	J Exerc Sci Fit	10.1016/j.jesf.2024.04.004	2024
Genetics	The effect of young blood plasma administration on gut microbiota in middle-aged rats.	Ceylani T, Teker HT.	Arch Microbiol	10.1007/s00203-022-03154-8	2022
Phylogeny	Progression of gut microbiome in preterm infants during the first three months.	Li F, Hooi SL, Choo YM, Teh CSJ, Toh KY, Lim LWZ, Lee YQ, Chong CW, Ahmad Kamar A.	Sci Rep	10.1038/s41598-025-95198-1	2025
	2'-Fucosyllactose as a prebiotic modulates the probiotic responses of Bifidobacterium bifidum.	Du J, Yang H.	Curr Res Food Sci	10.1016/j.crfs.2025.100975	2025
	Gut Microbiota and Exercise: Probiotics to Modify the Composition and Roles of the Gut Microbiota in the Context of 3P Medicine.	Liu Y, Hu Y, Ma B, Wang Z, Wei B.	Microb Ecol	10.1007/s00248-025-02529-w	2025
	Randomized double-blind placebo-controlled clinical trial to evaluate the effect of a mixture of probiotic strains on symptom severity and use of corticosteroids in children and adolescents with atopic dermatitis.	Feito-Rodriguez M, Ramirez-Bosca A, Vidal-Asensi S, Fernandez-Nieto D, Ros-Cervera G, Alonso-Usero V, Prieto-Merino D, Nunez-Delegido E, Ruzafa-Costas B, Sanchez-Pellicer P, Genoves S, Navarro-Lopez V.	Clin Exp Dermatol	10.1093/ced/llad007	2023
	Exercise combined with postbiotics treatment results in synergistic improvement of mitochondrial function in the brain of male transgenic mice for Alzheimer's disease.	Kolonics A, Bori Z, Torma F, Abraham D, Feher J, Radak Z.	BMC Neurosci	10.1186/s12868-023-00836-x	2023
	Engineered probiotics: a new era in treating inflammatory bowel disease.	Duan S, Wang Y, Zhan S, Ye Z, Luo T, Zhou Y, Xu H, Huang H.	J Transl Med	10.1186/s12967-025-07271-y	2025
	One-pot synthesis of cellobiose from sucrose using sucrose phosphorylase and cellobiose phosphorylase co-displaying Pichia pastoris as a reusable whole-cell biocatalyst.	Inokuma K, Toyohara K, Hamada T, Kondo A, Hasunuma T.	Sci Rep	10.1038/s41598-024-69676-x	2024
	Microbial signatures in metastatic cancer.	Bautista J, Fuentes-Yepez MP, Adatty-Molina J, Lopez-Cortes A.	Front Med (Lausanne)	10.3389/fmed.2025.1654792	2025
	Comparative effects of enteral nutrition strategies on nutritional indices, inflammatory factors, and clinical outcomes in patients with severe traumatic brain injury.	Chen H, Li Z, Xuan P, Yu L.	Am J Transl Res	10.62347/qroo6899	2025
	Immunoresponsive microbiota-gut-on-chip reproduces barrier dysfunction, stromal reshaping and probiotics translocation under inflammation.	De Gregorio V, Sgambato C, Urciuolo F, Vecchione R, Netti PA, Imparato G.	Biomaterials	10.1016/j.biomaterials.2022.121573	2022
Enzymology	High-resolution structure of phosphoketolase from Bifidobacterium longum determined by cryo-EM single-particle analysis.	Nakata K, Miyazaki N, Yamaguchi H, Hirose M, Kashiwagi T, Kutumbarao NHV, Miyashita O, Tama F, Miyano H, Mizukoshi T, Iwasaki K.	J Struct Biol	10.1016/j.jsb.2022.107842	2022
Phylogeny	Gut microbiota dysbiosis and short-chain fatty acid depletion in phlegm-dampness polycystic ovary syndrome: a cross-sectional 16S rRNA sequencing analysis.	Xia XY, Chen Y, Zhang XJ, Wang J, Xu HY, Zhao R.	BMC Endocr Disord	10.1186/s12902-025-02076-y	2025
	Bifidobacterium longum Subsp. infantis Promotes IgA Level of Growing Mice in a Strain-Specific and Intestinal Niche-Dependent Manner.	Ding M, Li B, Chen H, Ross RP, Stanton C, Zhao J, Chen W, Yang B.	Nutrients	10.3390/nu16081148	2024
Phylogeny	Study on biotransformation and absorption of genistin based on fecal microbiota and Caco-2 cell.	Li Z, Wang Y, Wang Z, Wu D, Zhao Y, Gong X, Jiang Q, Xia C.	Front Pharmacol	10.3389/fphar.2024.1437020	2024
	Comparison of bacterial and fungal biodiversity of Turkish kefir grains with high-throughput metagenomic analysis	Ilikkan OK, Bagdat ES.	Lebensm Wiss Technol		2021
Pathogenicity	Bifidobacterium longum subsp. longum 5^1A attenuates intestinal injury against irinotecan-induced mucositis in mice.	Quintanilha MF, Miranda VC, Souza RO, Gallotti B, Cruz C, Santos EA, Alvarez-Leite JI, Jesus LCL, Azevedo V, Trindade LM, Cardoso VN, Ferreira E, Carvalho BA, Soares PMG, Vieira AT, Nicoli JR, Martins FS.	Life Sci	10.1016/j.lfs.2021.120243	2022
	Anti-Inflammatory Peptides as Promising Therapeutics Agent Against Inflammatory Bowel Diseases: A Systematic Review.	Ghazvini K, Taghiabadi Z, Karimi MA, Hosseini Bafghi M, Paryan M, Amirfakhrian R.	JGH Open	10.1002/jgh3.70212	2025
	Probiotic Yoghurt Made from Milk of Ewes Fed a Diet Supplemented with Spirulina platensis or Fish Oil	Shazly AB, Khattab MSA, Fouad MT, Abd El Tawab AM, Saudi EM, El-Aziz MA.	Ann Microbiol		2022
	Gut Microbiota and Nutrition in Nursing Homes: Challenges and Translational Approaches for Healthy Aging.	Jimenez-Arroyo C, Molinero N, Moreno-Arribas MV.	Adv Nutr	10.1016/j.advnut.2025.100520	2025
Phylogeny	Analysis of gut microecological characteristics and differences between children with biliary atresia and non-biliary atresia in infantile cholestasis.	Liu Y, Zhang Y, Guo C, Li M, Wang Y, Zhang L.	Front Cell Infect Microbiol	10.3389/fcimb.2024.1402329	2024
	Mechanism-based inhibition of GH127/146 cysteine glycosidases by stereospecifically functionalized l-arabinofuranosides.	Ishiwata A, Narita S, Kimura K, Tanaka K, Fujita K, Fushinobu S, Ito Y.	Bioorg Med Chem	10.1016/j.bmc.2022.117054	2022
Cultivation	A novel selective medium for isolation of Limosilactobacillus reuteri from dietary supplements.	Wang YT, Chuang JW, Wu MS, Wang MC, Yang YC, Yang JJ, Chiou ST, Li CH, Lin CY, Huang SC, Tseng SH, Wang DY.	J Food Drug Anal	10.38212/2224-6614.3507	2024
	Pathogen exclusion from intestinal mucus and antimicrobial susceptibility of Bifidobacterium spp. strains from fecal donors.	Ronkainen A, Khan I, Satokari R.	Microbiome Res Rep	10.20517/mrr.2024.43	2025
Metabolism	Selenium-enriched Bifidobacterium longum DD98 attenuates irinotecan-induced intestinal and hepatic toxicity in vitro and in vivo.	Zhu H, Lu C, Gao F, Qian Z, Yin Y, Kan S, Chen D.	Biomed Pharmacother	10.1016/j.biopha.2021.112192	2021
	The Hazards of Probiotics on Gut-Derived Pseudomonas aeruginosa Sepsis in Mice Undergoing Chemotherapy.	Huang FC, Huang SC.	Biomedicines	10.3390/biomedicines12020253	2024
	Pretreatment with Bifidobacterium longum BAA2573 ameliorates dextran sulfate sodium (DSS)-induced colitis by modulating gut microbiota.	Lin Q, Hao WJ, Zhou RM, Huang CL, Wang XY, Liu YS, Li XZ.	Front Microbiol	10.3389/fmicb.2023.1211259	2023
	Effect of probiotics or prebiotics on thyroid function: A meta-analysis of eight randomized controlled trials.	Shu Q, Kang C, Li J, Hou Z, Xiong M, Wang X, Peng H.	PLoS One	10.1371/journal.pone.0296733	2024
	Insufficient immune protection in preterm infants due to delayed or incomplete hexavalent vaccination.	Kaiser E, Weber R, Bous M, Fortmann I, Dammann MT, Marissen J, Viemann D, Derouet C, Hein S, Nourkami-Tutdibi N, Tutdibi E, Wuhrmann M, Hans MC, Gille C, Gehring S, Henneke P, Hartel C, Goedicke-Fritz S, Zemlin M.	Front Immunol	10.3389/fimmu.2025.1626057	2025
	Plateau Environment, Gut Microbiota, and Depression: A Possible Concealed Connection?	Qiao Y, Cheng R, Li X, Zheng H, Guo J, Wei L, Gao T, Bi H.	Curr Issues Mol Biol	10.3390/cimb47070487	2025
	A survey of multiple candidate probiotic bacteria reveals specificity in the ability to modify the effects of key wound pathogens.	Alhubail M, McBain AJ, O'Neill CA.	Microbiol Spectr	10.1128/spectrum.00347-24	2024
Pathogenicity	Probiotics Enhance Bone Density and Reduce Inflammation Postalveolar Surgery.	Fu D, He X, Lu J, Du T.	Int Dent J	10.1016/j.identj.2025.100881	2025
	Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infections in a Cystic Fibrosis Child Previously Screen Positive, Inconclusive Diagnosis (CFSPID): A Case Report.	Marsiglia R, Pane S, Del Chierico F, Russo A, Vernocchi P, Romani L, Cardile S, Diamanti A, Galli L, Tamborino A, Terlizzi V, De Angelis P, Angelino G, Putignani L.	Microorganisms	10.3390/microorganisms12102059	2024
	Gut microbiota of preterm infants in the neonatal intensive care unit: a study from a tertiary care center in northern India.	Devarajalu P, Kumar J, Dutta S, Attri SV, Kabeerdoss J.	Front Microbiol	10.3389/fmicb.2024.1329926	2024
	In-silico assessment of dynamic symbiotic microbial interactions in a reduced microbiota related to the autism spectrum disorder symptoms.	Olaguez-Gonzalez JM, Chairez I, Breton-Deval L, Alfaro-Ponce M.	Comput Struct Biotechnol J	10.1016/j.csbj.2025.09.006	2025
Phylogeny	Identifying fecal microbiota signatures of colorectal cancer in a Vietnamese cohort.	Nhung PTT, Le HTT, Nguyen QH, Huyen DT, Quyen DV, Song LH, Van Thuan T, Tran TTT.	Front Microbiol	10.3389/fmicb.2024.1388740	2024
Metabolism	Alleviation of cognitive impairment by gut microbiota lipopolysaccharide production-suppressing Lactobacillus plantarum and Bifidobacterium longum in mice.	Lee DY, Shin YJ, Kim JK, Jang HM, Joo MK, Kim DH.	Food Funct	10.1039/d1fo02167b	2021
	Probiotic Microorganisms in Inflammatory Bowel Diseases: Live Biotherapeutics as Food.	Santos EN, Magalhaes-Guedes KT, Borges FEM, Ferreira DD, da Silva DF, Conceicao PCG, Lima AKC, Cardoso LG, Umsza-Guez MA, Ramos CL.	Foods	10.3390/foods13244097	2024
	Monensin phase-out in Norwegian turkey production decreases Bifidobacterium spp. abundance while enhancing microbial diversity.	Kaspersen HP, Estensmo EL, Slettemeas JS, Haverkamp THA, Sjurseth SK, Granstad S, Sekse C, Frederiksen RF, Urdahl AM.	Microb Genom	10.1099/mgen.0.001466	2025
	Resilience of the Gut Microbiome to Short Proton Pump Inhibitor Therapy With or Without High-Dosage L. reuteri in H. pylori-Infected Adults.	Bibbo S, Ahlstrom G, Pes GM, Graham DY, Engstrand L, Merola E, Dore MP.	Helicobacter	10.1111/hel.70064	2025
	Probiotics' Effects in the Treatment of Anxiety and Depression: A Comprehensive Review of 2014-2023 Clinical Trials.	Merkouris E, Mavroudi T, Miliotas D, Tsiptsios D, Serdari A, Christidi F, Doskas TK, Mueller C, Tsamakis K.	Microorganisms	10.3390/microorganisms12020411	2024
	[The effectiveness of a probiotic containing Bifidobacterium longum BB-46 and Enterococcus faecium ENCfa-68 in the treatment of post-infectious irritable bowel syndrome. Prospective randomized comparative study].	Yakovenko EP, Strokova TV, Ivanov AN, Iakovenko AV, Gioeva IZ, Aldiyarova MA.	Ter Arkh	10.26442/00403660.2022.02.201368	2022
	Association Between Vaginal Microbiota and Cervical Dysplasia Due to Persistent Human Papillomavirus Infection: A Systematic Review of Evidence from Shotgun Metagenomic Sequencing Studies.	Zukiene G, Narutyte R, Rudaitis V.	Int J Mol Sci	10.3390/ijms26094258	2025
	Probiotic therapy modulates the brain-gut-liver microbiota axis in a mouse model of traumatic brain injury.	Amaral WZ, Kokroko N, Treangen TJ, Villapol S, Gomez-Pinilla F.	Biochim Biophys Acta Mol Basis Dis	10.1016/j.bbadis.2024.167483	2024
	Safety and efficacy of oral cancer vaccine B440 in patients with PD-1/PD-L1 inhibitor-resistant advanced urothelial cancer: a study protocol for a phase 1 multicenter, open-label, single-arm clinical trial.	Furukawa J, Kakei Y, Murakami S, Kita H, Ueki H, Hara T, Teishima J, Hinata N, Miyake H, Fujisawa M, Shirakawa T.	BMC Cancer	10.1186/s12885-025-13514-4	2025
	Widespread vertical transmission of secretory immunoglobulin A coated trace bacterial variants from the mother to infant gut through breastfeeding.	Qi C, Tu H, Zhou J, Tu R, Chang H, Chen J, Hu H, Yu R, Sun J.	Food Funct	10.1039/d2fo01244h	2022
	Bifidobacterium longum and Chlorella sorokiniana Improve the IFN Type I-Mediated Antiviral Response in Rotavirus-Infected Cells.	Romero-Arguelles R, Tamez-Guerra P, Gonzalez-Ochoa G, Romo-Saenz CI, Gomez-Flores R, Flores-Mendoza L, Aros-Uzarraga E.	Microorganisms	10.3390/microorganisms11051237	2023
	Probiotics in inflammatory bowel diseases: emphasis on mechanisms and clinical application.	Zhang J, Zhang X, Cheng X, Wang S, Lv Y, Zheng X, Wu G.	Front Med (Lausanne)	10.3389/fmed.2025.1620079	2025
Genetics	A metagenome-wide association study of gut microbiota in hepatitis B virus-related cirrhosis in northwest China.	Feng M, Chai Y, Li J, Wang Q, Zhang D.	Front Genet	10.3389/fgene.2025.1619911	2025
	In Vitro Infant Fecal Fermentation Characteristics of Human Milk Oligosaccharides Were Controlled by Initial Microbiota Composition More than Chemical Structure.	Xu S, Lane JA, Chen J, Zheng Y, Wang H, Fu X, Huang Q, Dhital S, Liu F, Zhang B.	Mol Nutr Food Res	10.1002/mnfr.202200098	2022
	A comprehensive review of probiotics and human health-current prospective and applications.	Sarita B, Samadhan D, Hassan MZ, Kovaleva EG.	Front Microbiol	10.3389/fmicb.2024.1487641	2024
	Characterizing the fecal microbiome in patients on the ketogenic diet for drug resistant epilepsy.	Freibauer A, Pai N, RamachandranNair R.	Heliyon	10.1016/j.heliyon.2025.e41631	2025
	Bifidobacterium animalis subsp. lactis A6 alleviates perennial allergic rhinitis in adults by inhibiting serum total IgE and IL-13: A randomized, double-blind, placebo-controlled trial.	Wang L, Zhou S, Chen H, Zhang C, Sun M, Zhang Q, Liu Y, Shi S, Ge S, Chen J, Hao Y, Zhang Y, Fang B, He J, Wang R.	Clin Transl Allergy	10.1002/clt2.70064	2025
	Association of Gut Microbiota With Performance Level Among Iranian Professional and Semi-Professional Runners: A Cross-Sectional Study.	Nazari H, Meibodi AE, Bassami M, Olfatifar M, Yadegar A.	Health Sci Rep	10.1002/hsr2.71319	2025
	Microbial biomarkers and sex-associated gut microbiota characteristics of thyroid cancer.	Gou J, Hu Z, Cai M, Zhang S, Zhou S, Feng X, Tian Y, Li K, Hu X, Liu X, Pei X, Tian L, Zuo H, Fu MR.	BMC Cancer	10.1186/s12885-025-14986-0	2025
	Combination of Bifidobacterium longum and Galacto-Oligosaccharide Protects the Skin from Photoaging.	Kim D, Lee KR, Kim NR, Park SJ, Lee M, Kim OK.	J Med Food	10.1089/jmf.2021.k.0032	2021
	Multistrain probiotics alleviate gastrointestinal symptoms during bismuth quadruple therapy for Helicobacter pylori infection.	Liu WJ, Zhao YM, Xie QQ, Wu MC, Pan YF, Yan HK, Shan XX, Xu WT, Liu YL, Peng CX, Zhang XM, Lin Q.	World J Gastroenterol	10.3748/wjg.v31.i42.112577	2025
	Efficacy of bifidobacterium-related preparations on depression: the first meta-analysis.	Huang R, Liu Y.	Front Psychiatry	10.3389/fpsyt.2024.1463848	2024
	Metagenomic insights to understand the role of polluted river Yamuna in shaping the gut microbial communities of two invasive fish species.	Bharti M, Nagar S, Khurana H, Negi RK.	Arch Microbiol	10.1007/s00203-022-03127-x	2022
	Bifidobacterium longum suppresses colorectal cancer through the modulation of intestinal microbes and immune function.	Shang F, Jiang X, Wang H, Guo S, Kang S, Xu B, Wang X, Chen S, Li N, Liu B, Zhao Z.	Front Microbiol	10.3389/fmicb.2024.1327464	2024
Pathogenicity	Targeting gut microbiota dysbiosis in inflammatory bowel disease: a systematic review of current evidence.	Farah A, Paul P, Khan AS, Sarkar A, Laws S, Chaari A.	Front Med (Lausanne)	10.3389/fmed.2025.1435030	2025
Pathogenicity	Bifidobacterium longumBL-19 inhibits oxidative stress and inflammatory damage in the liver of mice with NAFLD by regulating the production of butyrate in the intestine.	Zhang X, Xu J, Dong X, Tang J, Xie Y, Yang J, Zou L, Wu L, Fan J.	Food Sci Nutr	10.1002/fsn3.4279	2024
	The role of probiotics, prebiotics, and synbiotics in the treatment of inflammatory bowel diseases: an overview of recent clinical trials	Yassine F, Najm A, Bilen M.	Front Syst Biol		2025
	Gram-positive probiotics improves acetaminophen-induced hepatotoxicity by inhibiting leucine and Hippo-YAP pathway.	Gao W, Wang G, Yuan H, Chen Y, Che J, Cheng Z, Chen L, Zhang L, Zhu Y, Liu X, Liu A, Yang Q, Cao P, Qian W, Huang W, Schnabl B, Yang L, Chu H.	Cell Biosci	10.1186/s13578-025-01370-5	2025
	The synergy of dietary supplements Lactobacillus salivarius LI01 and Bifidobacterium longum TC01 in alleviating liver failure in rats treated with D-galactosamine.	Zhuge A, Li S, Yuan Y, Li B, Li L.	Food Funct	10.1039/d1fo01807h	2021
	Construction of a Humanized PBMC-PDX Model to Study the Efficacy of a Bacterial Marker in Lung Cancer Immunotherapy.	Wu C, Wang X, Shang H, Wei H.	Dis Markers	10.1155/2022/1479246	2022
	Gut microbiota, inflammatory proteins and COVID-19: a Mendelian randomisation study.	Chen Y, Chen C.	Front Immunol	10.3389/fimmu.2024.1406291	2024
	Cross-country multi-modal evidence links Aspergillus to biliary atresia.	Huang SW, Lin CR, Chang YH, Ni YH, Chen HL, Liu HH.	Gut Pathog	10.1186/s13099-025-00772-7	2025
	The impact of diet and ethnicity on gut microbiota variation in irritable bowel syndrome: A multi-center study.	Khoo XH, Chong CW, Talha AM, Philip K, Teh CS, Isa AM, Wong MS, Chew DC, Wong Z, Jusoh NS, Maksum NMM, Mokhtar NM, Majid HA, Ali RAR, Lee YY, Mahadeva S.	J Gastroenterol Hepatol	10.1111/jgh.16174	2023
	The diversity and composition of the human gut lactic acid bacteria and bifidobacterial microbiota vary depending on age.	Ma T, Yao C, Shen X, Jin H, Guo Z, Zhai Q, Yu-Kwok L, Zhang H, Sun Z.	Appl Microbiol Biotechnol	10.1007/s00253-021-11625-z	2021
	Probiotic formulations and gastro-intestinal diseases in the paediatric population: a narrative review.	Siddiqui A, Haider R, Aaqil SI, Vohra LI, Qamar K, Jawed A, Fatima N, Adnan A, Parikh V, Ochani S, Hasibuzzaman MA.	Ann Med Surg (Lond)	10.1097/ms9.0000000000002007	2024
	Inaccurate labelling practices in probiotic products: A regulatory shortfall in Accra, Ghana.	Fredua-Agyeman M, Larbi EA.	PLoS One	10.1371/journal.pone.0322194	2025
	Effect of Probiotics in Stress-Associated Constipation Model in Zebrafish (Danio rerio) Larvae.	Lee A, Kim SY, Kang S, Kang SH, Kim DW, Choe JW, Hyun JJ, Jung SW, Jung YK, Koo JS, Yim HJ, Kim S.	Int J Mol Sci	10.3390/ijms25073669	2024
	Effect of Probiotics Supplementation on REM Sleep Behavior Disorder and Motor Symptoms in Parkinson's Disease: A Pilot Study.	Du Y, Wang L, Cui Y, Xu X, Zhang M, Li Y, Gao T, Gao D, Sheng Z, Wang S, Tuo H.	CNS Neurosci Ther	10.1111/cns.70541	2025
	Divergent Immunomodulatory Roles of Fungal DNA in Shaping Treg and Inflammatory Responses.	Li D, Cruz I, Feng Y, Moussa M, Cheng J, Patil D, Kroemer A, Bellanti JA.	J Fungi (Basel)	10.3390/jof11110760	2025
	Anti-Melanogenic and Antioxidant Activity of Bifidobacterium longum Strain ZJ1 Extracts, Isolated from a Chinese Centenarian.	Wu J, Zhang F, Yu H, Qi S, Wu Y, Xiao W.	Int J Mol Sci	10.3390/ijms241612810	2023
	An insight into an intriguing oxidative biotransformation pathway of 5-O-caffeoylquinic acid by a gut bacterium.	Balaj G, Tamanai-Shacoori Z, Olivier-Jimenez D, Sauvager A, Faustin M, Bousarghin L, David-Le Gall S, Guyot S, Nebija D, Tomasi S, Abasq ML.	Food Funct	10.1039/d1fo04304h	2022
	Evaluating the Effectiveness of Probiotic Supplementation in Combination With Doxycycline for the Treatment of Moderate Acne: A Randomized Double-Blind Controlled Clinical Trial.	Atefi N, Mohammadi M, Bodaghabadi M, Mehrali M, Behrangi E, Ghassemi M, Jafarzadeh A, Goodarzi A.	J Cosmet Dermatol	10.1111/jocd.16614	2025
	Maternal-infant probiotic transmission mitigates early-life stress-induced autism in mice.	Qing L, Qian X, Zhu H, Wang J, Sun J, Jin Z, Tang X, Zhao Y, Wang G, Zhao J, Chen W, Tian P.	Gut Microbes	10.1080/19490976.2025.2456584	2025
Pathogenicity	Evaluation of microecological therapy in endometriosis through modulation of the gut microbiota.	Qiao L, Zhao D, Wu J.	Eur J Med Res	10.1186/s40001-025-03334-4	2025
	The microbiome as a therapeutic co-driver in melanoma immuno-oncology.	Bautista J, Villegas-Chavez JA, Bunces-Larco D, Martin-Aguilera R, Lopez-Cortes A.	Front Med (Lausanne)	10.3389/fmed.2025.1673880	2025
	What happens to Bifidobacterium adolescentis and Bifidobacterium longum ssp. longum in an experimental environment with eukaryotic cells?	Jakubczyk D, Leszczynska K, Pacyga-Prus K, Kozakiewicz D, Kazana-Pluszka W, Gelej D, Migdal P, Kruszakin R, Zablocka A, Gorska S.	BMC Microbiol	10.1186/s12866-023-03179-z	2024
	Influence of Temperature during Freeze-Drying Process on the Viability of Bifidobacterium longum BB68S.	Sang Y, Wang J, Zhang Y, Gao H, Ge S, Feng H, Zhang Y, Ren F, Wen P, Wang R.	Microorganisms	10.3390/microorganisms11010181	2023
	Anti-aflatoxigenic effect of Lactobacillus rhamnosus and its synbiotic combination of chitosan/ZnO in milk.	Riad OKM, Selim HMRM, Tohamy STK, Aboshanab KM.	AMB Express	10.1186/s13568-025-01960-z	2025
	Efficacy of a food supplement based on S-adenosyl methionine and probiotic strains in subjects with subthreshold depression and mild-to-moderate depression: A monocentric, randomized, cross-over, double-blind, placebo-controlled clinical trial.	Ullah H, Di Minno A, Esposito C, El-Seedi HR, Khalifa SAM, Baldi A, Greco A, Santonastaso S, Cioffi V, Sperandeo R, Sacchi R, Daglia M.	Biomed Pharmacother	10.1016/j.biopha.2022.113930	2022
Genetics	Metabolites of the gut microbiota may serve as precise diagnostic markers for sarcopenia in the elderly.	He Y, Cui W, Fang T, Zhang Z, Zeng M.	Front Microbiol	10.3389/fmicb.2023.1301805	2023
	Exercise training combined with Bifidobacterium longum OLP-01 treatment regulates insulin resistance and physical performance in db/db mice.	Hsu YJ, Wu MF, Lee MC, Huang CC.	Food Funct	10.1039/d0fo02939d	2021
	Probiotics combined with prebiotics alleviated seasonal allergic rhinitis by altering the composition and metabolic function of intestinal microbiota: a prospective, randomized, double-blind, placebo-controlled clinical trial.	Hou Y, Wang D, Zhou S, Huo C, Chen H, Li F, Ding M, Li H, Zhao H, He J, Da H, Ma Y, Qiang Z, Chen X, Bai C, Cui J, Gao N, Liu Y.	Front Immunol	10.3389/fimmu.2024.1439830	2024
	Analysis of Gut Bacterial and Fungal Microbiota in Children with Autism Spectrum Disorder and Their Non-Autistic Siblings.	Retuerto M, Al-Shakhshir H, Herrada J, McCormick TS, Ghannoum MA.	Nutrients	10.3390/nu16173004	2024
	The Effect of Apple and Pear Cultivars on In Vitro Fermentation with Human Faecal Microbiota	Hoogeveen A, Butts C, Kim C, Jobsis C, Parkar S, Stoklosinski H, Sutton K, Davis P, Hedderley D, Johnston J, Gopal P.	Microorganisms		2025
Phylogeny	Structural Analysis and Antioxidant and Immunoregulatory Activities of an Exopolysaccharide Isolated from Bifidobacterium longum subsp. longum XZ01.	Zhang X, Gong J, Huang W, Liu W, Ma C, Liang R, Chen Y, Xie Z, Li P, Liao Q.	Molecules	10.3390/molecules28217448	2023
	Green synthesis of isomaltulose from cane molasses by an immobilized recombinant Escherichia coli strain and its prebiotic activity	Su HH, Xu RY, Yang ZD, Guo YS, Gao JY, Mo LZ, Gao YF, Cheng H, Zhang PJ, Huang JS.	Lebensm Wiss Technol		2022
	The role of microbiota modulation in preventing Alzheimer's disease- a review.	Strzepa A, Szczepanik M.	Pharmacol Rep	10.1007/s43440-025-00796-5	2025
	Prebiotic Structural Diversity Shapes Gut Microbial Diversity, Community Composition, and Metabolic Activity In Vitro.	Fu Y, Wang Y, Zhang J, Ren J, Fang B.	Foods	10.3390/foods14213774	2025
Pathogenicity	Correlation Analysis of Characteristics of Intestinal Microbiota and Cytokine Levels in Patients with Obstructive Sleep Apnea-Hypopnea Syndrome.	Liu KL, Xu SJ, Chen SW, Zhang MJ, Ye N, Li J.	Nat Sci Sleep	10.2147/nss.s471264	2024
	Effect of short-term consumption of yellow peas as noodles on the intestinal environment: A single-armed pre-post comparative pilot study.	Yamada M, Yoshimoto J, Maeda T, Ishii S, Kishi M, Taguchi T, Morita H.	Food Sci Nutr	10.1002/fsn3.3416	2023
	Birthmode and environment-dependent microbiota transmission dynamics are complemented by breastfeeding during the first year.	Selma-Royo M, Dubois L, Manara S, Armanini F, Cabrera-Rubio R, Valles-Colomer M, Gonzalez S, Parra-Llorca A, Escuriet R, Bode L, Martinez-Costa C, Segata N, Collado MC.	Cell Host Microbe	10.1016/j.chom.2024.05.005	2024
	Are probiotics effective in reducing the metabolic side effects of psychiatric medication? A scoping review of evidence from clinical studies.	Motteli S, Vetter S, Colla M, Hotzy F.	Transl Psychiatry	10.1038/s41398-024-02735-z	2024
Genetics	Scarless gene disruption enabled by a dual-plasmid knockout platform in a clinical infant-derived Bifidobacterium breve strain.	Gao Z, Feng L.	Front Microbiol	10.3389/fmicb.2025.1653505	2025
Phylogeny	MAGinator enables accurate profiling of de novo MAGs with strain-level phylogenies.	Zachariasen T, Russel J, Petersen C, Vestergaard GA, Shah S, Atienza Lopez P, Passali M, Turvey SE, Sorensen SJ, Lund O, Stokholm J, Brejnrod A, Thorsen J.	Nat Commun	10.1038/s41467-024-49958-8	2024
	Nutritional Strategies to Address Malnutrition in Dialyses Patients: A Systematic Review.	Arroyo-Serrano P, Alonso-Dominguez R, Mas-Fontao S, Gonzalez-Parra E, Sanchez-Tocino ML.	Nutrients	10.3390/nu17213478	2025
Pathogenicity	Protective role of short-chain fatty acids on intestinal oxidative stress induced by TNF-alpha.	Ferrer M, Buey B, Grasa L, Mesonero JE, Latorre E.	Cell Stress Chaperones	10.1016/j.cstres.2024.11.002	2024
	The association between prenatal exposure and childhood asthma: the mediating role of gut microbiota.	Ning Z, Zhang Y, Lu R, Zhao A, Wang Z, Yuan J, Li S.	Front Microbiol	10.3389/fmicb.2025.1664708	2025
Metabolism	Generating a fucose permease deletion mutant in Bifidobacterium longum subspecies infantis ATCC 15697.	Higgins MA, Ryan KS.	Anaerobe	10.1016/j.anaerobe.2021.102320	2021
	Vestibulodynia and the Vaginal Microbiome: A Case-Control Study.	Panzarella DA, Peresleni T, Collier JL, Kocis C, Baker DA.	J Sex Med	10.1016/j.jsxm.2022.06.014	2022
	Combined Administration of Lactobacillus or Bifidobacterium Offers Enhanced Antidepressant and Anxiolytic Activity in a Dose Dependent Manner.	Bankah AZ, Tagoe TA, Darko E, Agoha R, Ametefe EN, Kukuia KKE, Adjei S.	Brain Behav	10.1002/brb3.70564	2025
	Understanding the relationship between breast cancer, immune checkpoint inhibitors, and gut microbiota: a narrative review.	Hrubesz G, Leigh J, Ng TL.	Transl Breast Cancer Res	10.21037/tbcr-24-14	2024
	Probiotics supplementation in the treatment of male infertility: A Systematic Review.	Oliveira LCSL, Costa EC, Martins FDG, Rocha ASD, Brasil GA.	JBRA Assist Reprod	10.5935/1518-0557.20240013	2024
Pathogenicity	Influence of Maqian essential oil on gut microbiota and immunoresponses in type 1 diabetes: In silico study.	Dahab M, Idris H, Zhang P, Aladhadh M, Alatawi EA, Ming LC, Goh KW, Ser HL.	Heliyon	10.1016/j.heliyon.2024.e29490	2024
	A modular, reusable biocatalytic flow system for UDP-GlcNAc production.	Roberts TL, Dolan JP, Miller GJ, Lima MAD, Cosgrove SC.	React Chem Eng	10.1039/d5re00127g	2025
	Bifidobacterium longum subsp. infantis regulates Th1/Th2 balance through the JAK-STAT pathway in growing mice	Ding M, Li B, Chen H, Ross R, Stanton C, Jiang S, Zhao J, Chen W, Yang B.	Microbiome Res Rep		2024
	LPL-RH suppresses bone loss in ovariectomised rat models.	Chen WJ, Wang XL, Wang YF, Liu DM, Yue MY, Wei J, Li J, Chen TT, Tu HJ.	BMC Microbiol	10.1186/s12866-024-03683-w	2024
	Effect of a Multi-Strain Probiotic on Secretory Immunoglobulin-A Levels in Patients with Complete Edentulism: A Quasi-Experimental Study.	Kaur H, Dhawan P, Mahesh S, Gupta N.	J Int Soc Prev Community Dent	10.4103/jispcd.jispcd_36_25	2025
Enzymology	Direct loop-mediated isothermal amplification (LAMP) assay for rapid on-site detection of Bifidobacterium longum subspecies longum, infantis, and suis in probiotic products.	Kim MJ, Shin SW, Kim HB, Kim E, Kim HY.	Food Chem	10.1016/j.foodchem.2020.128887	2021
	Bifidobacterium longum subsp. infantis YB0411 Inhibits Adipogenesis in 3T3-L1 Pre-adipocytes and Reduces High-Fat-Diet-Induced Obesity in Mice.	Rahman MS, Kang I, Lee Y, Habib MA, Choi BJ, Kang JS, Park DS, Kim YS.	J Agric Food Chem	10.1021/acs.jafc.1c01440	2021
	The Potential Immunomodulatory Effect of Bifidobacterium longum subsp. longum BB536 on Healthy Adults through Plasmacytoid Dendritic Cell Activation in the Peripheral Blood.	Li Y, Arai S, Kato K, Iwabuchi S, Iwabuchi N, Muto N, Motobayashi H, Ebihara S, Tanaka M, Hashimoto S.	Nutrients	10.3390/nu16010042	2023
	Comparison of Plasmid Curing Efficiency across Five Lactic Acid Bacterial Species.	Park CH, Yang H, Kim S, Yun CS, Jang BC, Hong YJ, Park DS.	J Microbiol Biotechnol	10.4014/jmb.2406.06003	2024
	Prolonged effect of antibiotic therapy on the gut microbiota composition, functionality, and antibiotic resistance genes' profiles in healthy stool donors.	Karimianghadim R, Satokari R, Yeo S, Arkkila P, Kao D, Pakpour S.	Front Microbiol	10.3389/fmicb.2025.1589704	2025
	Bifidobacterium as a Potential Biomarker of Sarcopenia in Elderly Women.	Wang Z, Xu X, Deji Y, Gao S, Wu C, Song Q, Shi Z, Xiang X, Zang J, Su J.	Nutrients	10.3390/nu15051266	2023
	A synbiotic marine oligosaccharide microcapsules for enhancing Bifidobacterium longum survivability and regulatory on intestinal probiotics	Chang L, Wang P, Sun S, Shen Z, Jiang X.	International journal of food science and technology.	10.1111/ijfs.14650	2021
	Traditional Chinese herbal formulas modulate gut microbiome and improve insomnia in patients with distinct syndrome types: insights from an interventional clinical study.	Zeng H, Xu J, Zheng L, Zhan Z, Fang Z, Li Y, Zhao C, Xiao R, Zheng Z, Li Y, Yang L.	Front Cell Infect Microbiol	10.3389/fcimb.2024.1395267	2024
	Lactiplantibacillus (Lactobacillus) plantarum as a Complementary Treatment to Improve Symptomatology in Neurodegenerative Disease: A Systematic Review of Open Access Literature.	Beltran-Velasco AI, Reiriz M, Uceda S, Echeverry-Alzate V.	Int J Mol Sci	10.3390/ijms25053010	2024
	Effects of probiotic treatment on the prognosis of patients with sepsis: a systematic review.	Gong C, Xu S, Pan Y, Guo S, Walline JH, Wang X, Lu X, Yu S, Qin M, Zhu H, Gao Y, Li Y.	World J Emerg Med	10.5847/wjem.j.1920-8642.2025.018	2025
	Probiotic mouthwash as an adjunct to mechanical therapy in the treatment of stage II periodontitis: A randomized controlled clinical trial.	Ranjith A, Nazimudeen NB, Baiju KV.	Int J Dent Hyg	10.1111/idh.12589	2022
	Dynamics of Microbiome Changes in the Endometrium and Uterine Cervix during Embryo Implantation: A Comparative Analysis.	Bednarska-Czerwinska A, Morawiec E, Zmarzly N, Szapski M, Jendrysek J, Pecyna A, Zapletal-Pudelko K, Malysiak W, Sirek T, Ossowski P, Lach A, Boron D, Bogdal P, Bernet A, Grabarek BO.	Med Sci Monit	10.12659/msm.941289	2023
	Alleviation of Cognitive Impairment-like Behaviors, Neuroinflammation, Colitis, and Gut Dysbiosis in 5xFAD Transgenic and Aged Mice by Lactobacillus mucosae and Bifidobacterium longum.	Ma X, Kim JK, Shin YJ, Son YH, Lee DY, Park HS, Kim DH.	Nutrients	10.3390/nu15153381	2023
	Solid-State Fermentation of Riceberry Rice with Mushroom Mycelium for Enhanced Beta-Glucan Production and Health Applications.	Nacha J, Chen H, Owatworakit A, Saharat K, Makeudom A, Chamyuang S.	Molecules	10.3390/molecules30193879	2025
	Gut-Immune Interplay: Decoding the Microbiome's Impact on Immunity and Diseases.	Khazi AI, Ahmad A.	J Pharm Bioallied Sci	10.4103/jpbs.jpbs_1377_25	2025
	Limited Changes in Red Blood Cell Parameters After Probiotic Supplementation in Depressive Individuals: Insights from a Secondary Analysis of the PRO-DEMET Randomized Controlled Trial.	Gajewska A, Wysokinski A, Strzelecki D, Gawlik-Kotelnicka O.	J Clin Med	10.3390/jcm14010265	2025
Phylogeny	Cervical and Vaginal Microbiomes in Early Miscarriages and Ongoing Pregnancy with and without Dydrogesterone Usage.	Gryaznova M, Kozarenko O, Smirnova Y, Burakova I, Syromyatnikov M, Maslov A, Lebedeva O.	Int J Mol Sci	10.3390/ijms241813836	2023
	Alterations of Gut Microbiome, Metabolome, and Lipidome in Takayasu Arteritis.	Fan L, Chen J, Pan L, Xin X, Geng B, Yang L, Wang Q, Ma W, Lou Y, Bian J, Cui X, Li J, Wang L, Chen Z, Wang W, Cui C, Li S, Gao Q, Song Q, Deng Y, Fan J, Yu J, Zhang H, Li Y, Cai J.	Arthritis Rheumatol	10.1002/art.42331	2023
	[A prospective randomized comparative study of the efficacy and safety of a two-week bismuth-based quadrotherapy of Helicobacter pylori infection with the inclusion of the probiotic containing Bifidobacterium longum BB-46 and Enterococcus faecium ENCfa-68 ].	Yakovenko EP, Strokova TV, Iakovenko AV, Ivanov AN, Soluyanova IP, Vasilyev NN.	Ter Arkh	10.26442/00403660.2021.08.200996	2021
Metabolism	Identification of a Catalytic Nucleophile-Activating Network in the endo-alpha-N-Acetylgalactosaminidase of Family GH101.	Hansen AL, Koivisto JM, Simonsen S, Dong Z, Crehuet R, Hansen DK, Willemoes M.	Biochemistry	10.1021/acs.biochem.1c00596	2021
Metabolism	Genome-scale metabolic modeling of the human milk oligosaccharide utilization by Bifidobacterium longum subsp. infantis.	Roman L, Melis-Arcos F, Proschle T, Saa PA, Garrido D.	mSystems	10.1128/msystems.00715-23	2024
	Addition of 1, 4-alpha-glucan branching enzyme during the preparation of raw dough reduces the retrogradation and increases the slowly digestible fraction of starch in cooked noodles	Ji X, Zeng C, Yang D, Mu S, Shi Y, Huang Y, Lee BH, Li D, Li X.	J Cereal Sci	10.1016/j.jcs.2022.103431	2022
	Research progress of probiotics intervention on reconstruction of intestinal flora and improvement of quality of life in patients after endometrial cancer surgery.	Chen W, Chen X, Fang Y, Sun Y, Lin Y.	Front Cell Infect Microbiol	10.3389/fcimb.2025.1670836	2025
	Modulation of Bifidobacterium by HD5 during weaning is associated with high abundance in later life.	Shimizu Y, Yokoi Y, Ohira S, Izumi H, Kawakami S, Ihara M, Tabata F, Takeda Y, Kimura T, Nakamura K, Tamakoshi A, Ayabe T, Nakamura K.	Commun Med (Lond)	10.1038/s43856-025-00977-6	2025
Genetics	Neonatal microbiome dysbiosis decoded by mNGS: from mechanistic insights to precision interventions.	Huang F, Li J, Liu D, Li Y, Tang J.	Front Cell Infect Microbiol	10.3389/fcimb.2025.1642072	2025
	Longitudinal Fecal Microbiota Profiles in A Cohort of Non-Hospitalized Adolescents and Young Adults with COVID-19: Associations with SARS-CoV-2 Status and Long-Term Fatigue.	Olbjorn C, Hagen M, Moen AEF, Havdal LB, Sommen SL, Berven LL, Thiis-Evensen E, Stiansen-Sonerud T, Selvakumar J, Wyller VBB.	Pathogens	10.3390/pathogens13110953	2024
	Human milk oligosaccharides: bridging the gap in intestinal microbiota between mothers and infants.	Sun W, Tao L, Qian C, Xue PP, Du SS, Tao YN.	Front Cell Infect Microbiol	10.3389/fcimb.2024.1386421	2024
	Characterization and stabilization of GluLm and its application to deglycosylate dietary flavonoids and lignans.	Curiel JA, de la Bastida AR, Langa S, Peiroten A, Landete JM.	Appl Microbiol Biotechnol	10.1007/s00253-023-12956-9	2024
	Colorectal cancer and microbiota: systematic review.	Imanbayev N, Iztleuov Y, Bekmukhambetov Y, Abdelazim IA, Donayeva A, Amanzholkyzy A, Aigul Z, Aigerim I, Aslan Y.	Prz Gastroenterol	10.5114/pg.2024.136228	2024
Pathogenicity	Decoding the role of gut mycobiota in immune regulation and disease.	Zhang T, Guo F, Zhang C, Xiang Y.	Virulence	10.1080/21505594.2025.2541704	2025
	Viability of Microencapsulated Probiotics in Cross-Linked Alginate Matrices and Chia Seed or Flaxseed Mucilage During Spray-Drying and Storage.	Bustamante M, Oomah BD, Burgos-Diaz C, Vergara D, Flores L, Shene C.	Microorganisms	10.3390/microorganisms13071457	2025
	Can probiotics stop oral cancer progression?	Kumar SS.	Evid Based Dent	10.1038/s41432-022-0246-y	2022
	Characterization of whey protein isolate-gum Arabic Maillard conjugate and evaluation of the effects of conjugate-stabilized emulsion on microbiota of human fecal cultures	Kan X, Hu Y, Huang Y, Fan X, Chen G, Ye H, Zeng X.	Food hydrocolloids.		2022
	Research Progress on the Degradation of Human Milk Oligosaccharides (HMOs) by Bifidobacteria.	Cai R, Zhang J, Song Y, Liu X, Xu H.	Nutrients	10.3390/nu17030519	2025
	Isolation and identification of mucin-degrading bacteria originated from human faeces and their potential probiotic efficacy according to host-microbiome enterotype.	Yuan H, Zhou J, Li N, Wu X, Huang S, Park S.	J Appl Microbiol	10.1111/jam.15560	2022
	A low glycemic index, energy-restricted diet but not Lactobacillus rhamnosus supplementation changes fecal short-chain fatty acid and serum lipid concentrations in women with overweight or obesity and polycystic ovary syndrome.	Lagowska K, Drzymala-Czyz S.	Eur Rev Med Pharmacol Sci	10.26355/eurrev_202202_28001	2022
	Deciphering the Potential of Probiotics in Vaccines.	Xu C, Aqib AI, Fatima M, Muneer S, Zaheer T, Peng S, Ibrahim EH, Li K.	Vaccines (Basel)	10.3390/vaccines12070711	2024
	The Role of Bifidobacterium in COVID-19: A Systematic Review.	Taufer CR, Rampelotto PH.	Life (Basel)	10.3390/life13091847	2023
	Identification of the key characteristics of Bifidobacterium longum strains for the alleviation of ulcerative colitis.	Zhang C, Zhao Y, Jiang J, Yu L, Tian F, Zhao J, Zhang H, Chen W, Chen W, Zhai Q.	Food Funct	10.1039/d1fo00017a	2021
	In Vitro Hypoglycemic Activities of Lactobacilli and Bifidobacterium Strains from Healthy Children's Sources and Their Effect on Stimulating GLP-1 Secretion in STC-1 Cells.	Cheng Z, Chen J, Zhang Y, Li X, Zhang N, Liu F, Jiao Y.	Foods	10.3390/foods13040519	2024
	Agarooligosaccharides as a novel concept in prebiotics: selective inhibition of Ruminococcus gnavus and Fusobacterium nucleatum while preserving Bifidobacteria, Lactobacillales in vitro, and inhibiting Lachnospiraceae in vivo.	Fujii T, Karasawa K, Takahashi H, Shirai I, Funasaka K, Ohno E, Hirooka Y, Tochio T.	Microbiology (Reading)	10.1099/mic.0.001510	2024
	A systematic review of microbiome composition in osteoarthritis subjects.	Bonato A, Zenobi-Wong M, Barreto G, Huang Z.	Osteoarthritis Cartilage	10.1016/j.joca.2021.12.006	2022
Pathogenicity	Preventive oral supplementation with Bifidobacterium longum 5^1A alleviates oxazolone-induced allergic contact dermatitis-like skin inflammation in mice.	Ribeiro WR, Queiroz AG, Mendes E, Casaro MB, Nascimento CM, Coelho LSSF, Martins FS, Leite-Silva VR, Ferreira CM.	Benef Microbes	10.3920/bm2020.0134	2021
	Modulation of Gut Microbiota Using VSL#3 and Its Impact on Aortic Parameters in a Rat Model.	Altun M, Kucuk U, Yildirim N.	Anatol J Cardiol	10.14744/anatoljcardiol.2025.5048	2025
	Fiber Intervention Study in Prader-Willi Syndrome: Insights into Metabolic and Microbiota Shifts.	Tan Q, Peng Y, Deehan EC, Vieira FT, Ho BWP, Afhami S, Wine E, Madsen KL, Field CJ, Pakseresht M, Ilkayeva O, Newgard CB, Walter J, Tun HM, Haqq AM.	J Clin Endocrinol Metab	10.1210/clinem/dgaf142	2025
	Engineering Probiotics for Diabetes Management: Advances, Challenges, and Future Directions in Translational Microbiology.	Zhang S, Ma J, Ma Y, Yi J, Wang B, Wang H, Yang Q, Zhang K, Yan X, Sun D, You J.	Int J Nanomedicine	10.2147/ijn.s492651	2024
	A Comprehensive Overview of the Past, Current, and Future Randomized Controlled Trials in Hepatic Encephalopathy.	Ilie OD, Duta R, Nita IB, Dobrin I, Gurzu IL, Girleanu I, Huiban L, Muzica C, Ciobica A, Popescu R, Cianga P, Stanciu C, Cimpoesu D, Trifan A.	Medicina (Kaunas)	10.3390/medicina59122143	2023
	Efficacy and safety of Bacteroides fragilis BF839 for pediatric autism spectrum disorder: a randomized clinical trial.	Lin CH, Zeng T, Lu CW, Li DY, Liu YY, Li BM, Chen SQ, Deng YH.	Front Nutr	10.3389/fnut.2024.1447059	2024
Phenotype	Gene-trait matching analysis reveals putative genes involved in Bifidobacterium spp. biofilm formation.	Liu Z, Li H, Li L, Ma Q, Fang Z, Wang H, Lee Y, Zhao J, Zhang H, Chen W, Lu W.	Gene	10.1016/j.gene.2022.146449	2022
	The Bacterial Composition of the Gut Microbiota of Mexicans with Overweight and Obesity: A Systematic Review	Samudio-Cruz M, Luna-Angulo A, Cabrera-Ruiz E, Landa-Solis C, Rangel-Lopez E, Carrillo-Mora P, Rios-Martinez J, Toledo-Perez R, Paniagua-Perez R, Martinez-Canseco C, Lino-Gonzalez A, Saldana Solano A, Sanchez-Chapul L.	Microorganisms		2025
	Delayed colonization of Bifidobacterium spp. and low prevalence of B. infantis among infants of Asian ancestry born in Singapore: insights from the GUSTO cohort study.	Xu J, Duar RM, Quah B, Gong M, Tin F, Chan P, Sim CK, Tan KH, Chong YS, Gluckman PD, Frese SA, Kyle D, Karnani N.	Front Pediatr	10.3389/fped.2024.1421051	2024
	mbSparse: an autoencoder-based imputation method to address sparsity in microbiome data.	Qi C, Cai Y, He G, Qian K, Guo M, Cheng L.	Gut Microbes	10.1080/19490976.2025.2552347	2025
Metabolism	Exposure to anti-seizure medications impact growth of gut bacterial species and subsequent host response.	Ilhan ZE, Brochard V, Lapaque N, Auvin S, Lepage P.	Neurobiol Dis	10.1016/j.nbd.2022.105664	2022
	Gut feeling gone wrong: Tangled relationship between disorders of gut-brain interaction and liver disease.	Goyal MK, Goyal P, Goyal O, Sood A.	World J Hepatol	10.4254/wjh.v17.i5.105582	2025
	Footprint of Domestic Processing on Safety and Functional Properties of Italian Black Garlic	Addazii D, Cevoli C, Casciano F, Ferioli F, Gallina Toschi T, Gianotti A, Nissen L.	Foods		2025
	Synergistic Effects of an Eight-Week Resistance Training and Probiotic Supplementation on Bone Metabolism in Ovariectomized Rats.	Nasabeh Asl S, Daryanoosh F, Shekarforoush SS, Tanideh N, Koohi-Hosseinabadi O, Khorshidian A, Zarifkar AH.	Prev Nutr Food Sci	10.3746/pnf.2025.30.4.323	2025
	In Vitro Evaluation of Probiotic Properties and Anti-Pathogenic Effects of Lactobacillus and Bifidobacterium Strains as Potential Probiotics.	Lee J, Jo J, Wan J, Seo H, Han SW, Shin YJ, Kim DH.	Foods	10.3390/foods13142301	2024
	Investigation into the effects of CbXyn10C and Xyn11A on xylooligosaccharide profiles produced from sugarcane bagasse and rice straw and their impact on probiotic growth.	Gufe C, Ngenyoung A, Rattanarojpong T, Khunrae P.	Bioresour Technol	10.1016/j.biortech.2021.126319	2022
Metabolism	Comparative genomics and in silico gene evaluation involved in the probiotic potential of Bifidobacterium longum 5^1A.	da Silva JGV, Vieira AT, Sousa TJ, Viana MVC, Parise D, Sampaio B, da Silva AL, de Jesus LCL, de Carvalho PKRML, de Castro Oliveira L, Aburjaile FF, Martins FS, Nicoli JR, Ghosh P, Brenig B, Azevedo V, Gomide ACP.	Gene	10.1016/j.gene.2021.145781	2021
	Drawbacks of antibiotic regimen following cesarean deliveries on beneficial bacteria in colostrum, a prospective observational study.	Mousa AB, Abdel-Rasheed M, Moawad RMS.	BMC Nutr	10.1186/s40795-025-01143-w	2025
	An 8-Week Course of Bifidobacterium longum 35624^® Is Associated with a Reduction in the Symptoms of Irritable Bowel Syndrome.	Lenoir M, Wienke J, Fardao-Beyler F, Roese N.	Probiotics Antimicrob Proteins	10.1007/s12602-023-10151-w	2025
	Lactation-dependent vertical transmission of natural probiotics from the mother to the infant gut through breast milk.	Qi C, Zhou J, Tu H, Tu R, Chang H, Chen J, Li D, Sun J, Yu R.	Food Funct	10.1039/d1fo03131g	2022
	Randomized, Double-Blind, Placebo-Controlled Study to Assess the Effect of Two Probiotics on the Preterms' Gut Microbiota.	Moreno-Sanz B, Montes MT, Manzano S, Espinosa-Martos I, Cardenas N, Esteban S, Cruz M, Jimenez E, de Pipaon MS.	J Pediatr Gastroenterol Nutr	10.1097/mpg.0000000000003427	2022
	Clostridium butyricum-altered lung microbiome is associated with enhanced anti-influenza effects via G-protein-coupled receptor120.	Hagihara M, Yamashita M, Ariyoshi T, Minemura A, Yoshida C, Higashi S, Oka K, Takahashi M, Ota A, Maenaka A, Iwasaki K, Hirai J, Shibata Y, Umemura T, Mori T, Kato H, Asai N, Mikamo H.	iScience	10.1016/j.isci.2025.113502	2025
Phylogeny	Effects of fructooligosaccharides (FOS) on the composition of cecal and fecal microbiota and the quantitative detection of FOS-metabolizing bacteria using species-specific primers.	Gu J, Cui S, Tang X, Liu Z, Zhao J, Zhang H, Mao B, Chen W.	J Sci Food Agric	10.1002/jsfa.11884	2022
	Effect of Composite Probiotics on Antioxidant Capacity, Gut Barrier Functions, and Fecal Microbiome of Weaned Piglets and Sows.	Tang J, Zhao M, Yang W, Chen H, Dong Y, He Q, Miao X, Zhang J.	Animals (Basel)	10.3390/ani14091359	2024
	Probiotics as Potential Treatments for Neurodegenerative Diseases: a Review of the Evidence from in vivo to Clinical Trial.	Kim JH, Choi Y, Lee S, Oh MS.	Biomol Ther (Seoul)	10.4062/biomolther.2024.215	2025
	An Exopolysaccharide Produced by Bifidobacterium longum 35624® Inhibits Osteoclast Formation via a TLR2-Dependent Mechanism.	Wallimann A, Hildebrand M, Groeger D, Stanic B, Akdis CA, Zeiter S, Richards RG, Moriarty TF, O'Mahony L, Thompson K.	Calcif Tissue Int	10.1007/s00223-020-00790-4	2021
	Probiotic Supplementation Enhances the Effects of a Nutritional Intervention on Quality of Life in Women with Hashimoto's Thyroiditis-A Double-Blind Randomised Study.	Osowiecka K, Skrypnik D, Myszkowska-Ryciak J.	Nutrients	10.3390/nu17213387	2025
	Preventive role of Pastinaca sativa in mitigating metabolic dysfunction-associated steatotic liver disease via modulation of metabolic endotoxemia.	Park JE, Lee HB, Lee YR, Yoo G, Son HK, Choi SY, Park M, Park HY.	NPJ Sci Food	10.1038/s41538-024-00366-8	2025
	Evaluation of skin cancer prevention properties of probiotics.	Torabi S, Nahidi Y, Ghasemi SZ, Reihani A, Samadi A, Ramezanghorbani N, Nazari E, Davoudi S.	Genes Nutr	10.1186/s12263-025-00770-z	2025
	The ameliorative role of specific probiotic combinations on bone loss in the ovariectomized rat model.	Gholami A, Dabbaghmanesh MH, Ghasemi Y, Koohpeyma F, Talezadeh P, Montazeri-Najafabady N.	BMC Complement Med Ther	10.1186/s12906-022-03713-y	2022
	Probiotic strains alleviated OVA-induced food allergy in mice by regulating the gut microbiota and improving the level of indoleacrylic acid in fecal samples.	Lu W, Qian L, Fang Z, Wang H, Zhu J, Lee YK, Zhao J, Zhang H, Chen W, Chen W.	Food Funct	10.1039/d1fo03520g	2022
	Understanding the role of the gut microbiome in solid tumor responses to immune checkpoint inhibitors for personalized therapeutic strategies: a review.	Lim MY, Hong S, Nam YD.	Front Immunol	10.3389/fimmu.2024.1512683	2024
Pathogenicity	Comparison of novel native probiotics and paraprobiotics in modulating oxidative stress and inflammation in DSS-induced colitis: implications for enhanced therapeutic strategies in high fat diet.	Rezaie N, Aghamohammad S, Gholizadeh Khiavi EHA, Pourshafie MR, Talebi M, Rohani M.	BMC Immunol	10.1186/s12865-024-00678-0	2024
	Nutraceuticals and pharmacological to balance the transitional microbiome to extend immunity during COVID-19 and other viral infections.	Kaushal A.	J Transl Med	10.1186/s12967-024-05587-9	2024
	Recent advances in gut microbiota and thyroid disease: pathogenesis and therapeutics in autoimmune, neoplastic, and nodular conditions.	Fang L, Ning J.	Front Cell Infect Microbiol	10.3389/fcimb.2024.1465928	2024
Phylogeny	Exploring the Intestinal Microbiota Profile in Prostate Cancer Patients and Healthy Controls.	Cocomazzi G, Villani A, Mencarelli G, Contu V, De Ruvo D, Virgili E, Marino F, Baldini GM, Binda E, Parmegiani L, Ciampaglia W, Capone L, Perri F, Cisternino A, Pazienza V, Panebianco C.	Microorganisms	10.3390/microorganisms13092105	2025
	The effects of probiotic supplementation and exercise training on liver enzymes and cardiometabolic markers in patients with non-alcoholic fatty liver disease: a systematic review and meta-analysis of randomized clinical trials.	Kazeminasab F, Miraghajani M, Mokhtari K, Karimi B, Rosenkranz SK, Santos HO.	Nutr Metab (Lond)	10.1186/s12986-024-00826-8	2024
	Fabrication of fish gelatin / sodium alginate double network gels for encapsulation of probiotics	Liu J, Liu F, Ren T, Wang J, Yang M, Yao Y, Chen H.	Journal of the Science of Food and Agriculture.		2021
	Bile Salt Hydrolase Activity-Based Probes for Monitoring Gut Microbial Bile Acid Metabolism.	Han L, Xu R, Conwell AN, Takahashi S, Parasar B, Chang PV.	Chembiochem	10.1002/cbic.202300821	2024
Pathogenicity	Healing from Within: How Gut Microbiota Predicts IBD Treatment Success-A Systematic Review.	Alexandrescu L, Nicoara AD, Tofolean DE, Herlo A, Nelson Twakor A, Tocia C, Trandafir A, Dumitru A, Dumitru E, Aftenie CF, Preotesoiu I, Dina E, Tofolean IT.	Int J Mol Sci	10.3390/ijms25158451	2024
	Substrate complex structure, active site labeling and catalytic role of the zinc ion in cysteine glycosidase.	Maruyama S, Sawano K, Amaki S, Suzuki T, Narita S, Kimura K, Arakawa T, Yamada C, Ito Y, Dohmae N, Fujita K, Ishiwata A, Fushinobu S.	Glycobiology	10.1093/glycob/cwab103	2022
Genetics	Genomic and stress resistance characterization of Lactiplantibacillus plantarum GX17, a potential probiotic for animal feed applications.	Yin Y, Li C, Pei Z, Li C, Chen Z, Bai H, Ma C, Lan M, Li J, Gong Y, Liu J, Teng L, Wang L, Qin Z, Zhang E, Peng H.	Microbiol Spectr	10.1128/spectrum.01243-25	2025
Metabolism	Bifidobacterium species associated with breastfeeding alleviate neonatal hyperbilirubinaemia via the gut microbiota-alpha-linolenic and linoleic acid metabolism-enterohepatic circulation axis.	Lin C, Lin Y, Xiao R, Guo M, Zhang H, Chen W, Wang G.	Microbiome	10.1186/s40168-025-02190-y	2025
	Effective removal of lead (II) using chitosan and microbial adsorbents: Response surface methodology (RSM).	Khanniri E, Yousefi M, Mortazavian AM, Khorshidian N, Sohrabvandi S, Arab M, Koushki MR.	Int J Biol Macromol	10.1016/j.ijbiomac.2021.02.065	2021
	Association Between the Mode of Delivery and Infant Gut Microbiota Composition Up to 6 Months of Age: A Systematic Literature Review Considering the Role of Breastfeeding.	Princisval L, Rebelo F, Williams BL, Coimbra AC, Crovesy L, Ferreira AL, Kac G.	Nutr Rev	10.1093/nutrit/nuab008	2021
	The Benefits of Prebiotics and Probiotics on Mental Health.	Bistas KG, Tabet JP.	Cureus	10.7759/cureus.43217	2023
	Potentiated antitumor effects of APS001F/5-FC combined with anti-PD-1 antibody in a CT26 syngeneic mouse model.	Shioya K, Matsumura T, Seki Y, Shimizu H, Nakamura T, Taniguchi S.	Biosci Biotechnol Biochem	10.1093/bbb/zbaa057	2021
	Identification and characterization of two AA9 lytic polysaccharide monooxygenases isolated from the enzymatic arsenal in Phanerochaete chrysosporium.	Xu X, Chu CE, Li N, Sun XB, Han J, Xu Z, Liu Y, Wang JK, Zhang TT, Wang Q.	Bioresour Bioprocess	10.1186/s40643-025-00950-0	2025
	Exploring Therapeutic Advances: A Comprehensive Review of Intestinal Microbiota Modulators.	Pires L, Gonzalez-Paramas AM, Heleno SA, Calhelha RC.	Antibiotics (Basel)	10.3390/antibiotics13080720	2024
	[Prospects of probiotic strains of bifidobacteria and enterococcus in treatment and prevention of diseases in gastroenterology].	Shikh EV, Makhova AA, Astapovskiy AA, Perkov AV.	Vopr Pitan	10.33029/0042-8833-2021-90-2-15-25	2021
	In vitro conversion of ellagic acid to urolithin A by different gut microbiota of urolithin metabotype A.	He F, Bian Y, Zhao Y, Xia M, Liu S, Gui J, Hou X, Fang Y.	Appl Microbiol Biotechnol	10.1007/s00253-024-13061-1	2024
	Growth progression and hematobiochemical dynamics in broiler chickens treated with antibiotic, probiotic, and acidifier.	Islam MM, Islam MS, Sujan KM, Miah MA.	Open Vet J	10.5455/ovj.2025.v15.i8.11	2025
	Impact of Fermentation of Pumpkin Leaves and Melon Varieties with Lactobacillus Strains on Physicochemical Properties, Antioxidant Activity, and Carotenoid Compounds.	Mhlanga P, Mianda SM, Sivakumar D.	Foods	10.3390/foods13223562	2024
Pathogenicity	The Efficacy and Safety of Probiotic Combinations Lobun Forte® Versus Renadyl® in Patients With Chronic Kidney Disease: A Comparative, Phase IV, Randomized, Open-Label, Active-Controlled, Parallel Study.	Kalidindi RK, Reddy CP, Pv K, Kompella P.	Cureus	10.7759/cureus.67987	2024
	Review of Integrative Medical Therapies for Psoriasis: The Microbiome, Probiotics, Diet, and Mindfulness.	Min M, Dulai AS, Ahmad N, Sivamani RK.	J Psoriasis Psoriatic Arthritis	10.1177/24755303241236386	2024
	Bifidobacterium bifidum reduces oxidative stress and alters gut flora to mitigate acute liver injury caused by N-acetyl-p-aminophenol.	Yin J, Chen L, Lin Y, Qiu J, Liu F, Wang Y, Dou X.	BMC Microbiol	10.1186/s12866-025-03775-1	2025
	Effectiveness of Probiotics, Prebiotics, and Synbiotics in Managing Insulin Resistance and Hormonal Imbalance in Women with Polycystic Ovary Syndrome (PCOS): A Systematic Review of Randomized Clinical Trials.	Martinez Guevara D, Vidal Canas S, Palacios I, Gomez A, Estrada M, Gallego J, Liscano Y.	Nutrients	10.3390/nu16223916	2024
Pathogenicity	Probiotic Bifidobacterium longum subsp. longum Protects against Cigarette Smoke-Induced Inflammation in Mice.	Budden KF, Gellatly SL, Vaughan A, Amorim N, Horvat JC, Hansbro NG, Wood DLA, Hugenholtz P, Dennis PG, Wark PAB, Hansbro PM.	Int J Mol Sci	10.3390/ijms24010252	2022
	The prebiotic effect of 1-kestose in low-birth-weight neonates taking bifidobacteria: a pilot randomized trial in comparison with lactulose.	Tanaka S, Takahashi M, Takeshita K, Nagasawa K, Takei H, Sato H, Hishiki H, Ishiwada N, Hamada H, Kadota Y, Tochio T, Ishida T, Sasaki K, Tomita M, Osone Y, Takemura R, Shimojo N.	Biosci Microbiota Food Health	10.12938/bmfh.2023-079	2024
	Influence and Selection of Probiotics on Depressive Disorders in Occupational Health: Scoping Review.	Pico-Monllor JA, Sala-Segura E, Tobares RA, Moreno-Ochando A, Hernandez-Teruel A, Navarro-Lopez V.	Nutrients	10.3390/nu15163551	2023
	Impact of probiotics on cognition and constipation in the elderly: A meta-analysis.	Recharla N, Choi J, Puligundla P, Park SJ, Lee HJ.	Heliyon	10.1016/j.heliyon.2023.e18306	2023
Genetics	Precision Nutrition and Gut-Brain Axis Modulation in the Prevention of Neurodegenerative Diseases.	Tuigunov D, Sinyavskiy Y, Nurgozhin T, Zholdassova Z, Smagul G, Omarov Y, Dolmatova O, Yeshmanova A, Omarova I.	Nutrients	10.3390/nu17193068	2025
	Verification of an alteration in the gut microbiota that increases nutritional risk in patients on hemodialysis.	Fukuhara S, Ohmori H, Matsumoto T, Takei D, Matsuoka K, Takemoto M, Sumimoto R, Ohdan H.	Biosci Microbiota Food Health	10.12938/bmfh.2024-048	2025
	Free lipoproteins from Bifidobacterium longum alleviate osteoarthritis through modulation of the gut microbiome.	Sane F, Piva F, Romond MB.	Microbiome Res Rep	10.20517/mrr.2023.12	2023
	Coeliac disease and microbiota: is it time for personalised biotics intervention? A scoping review.	Valitutti F, Cavalli E, Leter B, Leonard M, Alessio F, Cucchiara S.	BMJ Nutr Prev Health	10.1136/bmjnph-2024-001100	2025
	Effects of systemic Bifidobacterium longum and Lactobacillus rhamnosus probiotics on the ligature-induced periodontitis in rat.	Chen YW, Lee ML, Chiang CY, Fu E.	J Dent Sci	10.1016/j.jds.2023.04.013	2023
	Fecal Bacterial Communities Differ by Lactation Status in Postpartum Women and Their Infants.	Haddad EN, Ferro LE, Russell KEB, Sugino KY, Kerver JM, Comstock SS.	J Hum Lact	10.1177/08903344211060343	2022
	The adhesion of the gut microbiota to insoluble dietary fiber from soy hulls promoted the proliferation of probiotics in vitro	Li L, Zhao Y, Li J, Ban L, Yang L, Wang S, Zhu L, Song H, Liu H.	Lebensm Wiss Technol		2021
Pathogenicity	A Narrative Review on Gut Microbiome Disturbances and Microbial Preparations in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Implications for Long COVID.	Jurek JM, Castro-Marrero J.	Nutrients	10.3390/nu16111545	2024
	Exploring the genomic traits of infant-associated microbiota members from a Zimbabwean cohort.	Mudhluli TE, Kujawska M, Mueller J, Felsl A, Truppel BA, Hall LJ, Chitsike I, Gomo E, Zhou DT.	BMC Genomics	10.1186/s12864-024-10618-2	2024
	The Relationship Between Gut Microbiota, Muscle Mass and Physical Function in Older Individuals: A Systematic Review.	Barry DJ, Wu SSX, Cooke MB.	Nutrients	10.3390/nu17010081	2024
	Lactulose selectively stimulates members of the gut microbiota, as determined by multi-modal activity-based sorting.	Rasoulimehrabani H, Riva A, Inan D, Hodzic A, Hausmann B, Nikolov G, Khadem S, Hieger N, Wiesenbauer J, Kaiser C, Filz V, Bottcher T, Berry D.	Gut Microbes	10.1080/19490976.2025.2525482	2025
	Food colorant brilliant blue causes persistent functional and structural changes in an in vitro simplified microbiota model system.	Castaneda-Monsalve V, Haange SB, Frohlich LF, Fu Q, Rolle-Kampczyk U, von Bergen M, Jehmlich N.	ISME Commun	10.1093/ismeco/ycaf050	2025
	The Effect of Microbiome-Modulating Agents (MMAs) on Type 1 Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.	Zhang Y, Huang A, Li J, Munthali W, Cao S, Putri UMP, Yang L.	Nutrients	10.3390/nu16111675	2024
	Regulatory mechanism of cysteine-dependent methionine biosynthesis in Bifidobacterium longum: insights into sulfur metabolism in gut microbiota.	Kim YT, Kwon JG, O'Sullivan DJ, Lee JH.	Gut Microbes	10.1080/19490976.2024.2419565	2024
Metabolism	N-Glycan Degradation Pathways in Gut- and Soil-Dwelling Actinobacteria Share Common Core Genes.	Higgins MA, Tegl G, MacDonald SS, Arnal G, Brumer H, Withers SG, Ryan KS.	ACS Chem Biol	10.1021/acschembio.0c00995	2021
Enzymology	Recombinant Bile Salt Hydrolase Enhances the Inhibition Efficiency of Taurodeoxycholic Acid against Clostridium perfringens Virulence.	Alenezi T, Alrubaye B, Fu Y, Shrestha J, Algehani S, Wang H, Liyanage R, Sun X.	Pathogens	10.3390/pathogens13060464	2024
Pathogenicity	Heat-Killed Bifidobacterium longum BBMN68 in Pasteurized Yogurt Alleviates Mugwort Pollen-Induced Allergic Airway Responses through Gut Microbiota Modulation in a Murine Model.	Niu X, Yin X, Wu X, Zhang Q, Jiang Y, He J, Zhao Y, Zhang C, Ren Y, Lai M, Sang Y, Wang R.	Foods	10.3390/foods12102049	2023
	Application of bifidobacterium in tumor therapy	Kong Y, Bai H, Deng F, Zhao Y, Li Q, Chang L.	Front Oncol		2025
	Assessment of the safety and gut microbiota modulation ability of an infant formula containing Bifidobacterium animalis ssp. lactis CP-9 or Lactobacillus salivarius AP-32 and the effects of the formula on infant growth outcomes: insights from a four-month clinical study in infants under two months old.	Shen SP, Lin HC, Chen JF, Wang HS, Huang YY, Hsia KC, Lin JH, Kuo YW, Li CM, Hsu YC, Tsai SY, Ho HH.	BMC Pediatr	10.1186/s12887-024-05289-7	2024
	Insights into the Relationship Between the Gut Microbiome and Immune Checkpoint Inhibitors in Solid Tumors.	Ciernikova S, Sevcikova A, Novisedlakova M, Mego M.	Cancers (Basel)	10.3390/cancers16244271	2024
	Probiotic bacteria vs. yeast for gastrointestinal diseases treatment: Protocol for a systematic review and meta-analysis.	Alsalemi W, Chik Z, Alshawsh MA.	PLoS One	10.1371/journal.pone.0324926	2025
	The Effect of Proline on the Freeze-Drying Survival Rate of Bifidobacterium longum CCFM 1029 and Its Inherent Mechanism.	Cui S, Zhou W, Tang X, Zhang Q, Yang B, Zhao J, Mao B, Zhang H.	Int J Mol Sci	10.3390/ijms232113500	2022
	Role of probiotic extracellular vesicles in inter-kingdom communication and current technical limitations in advancing their therapeutic utility.	Sanwlani R, Bramich K, Mathivanan S.	Extracell Vesicles Circ Nucl Acids	10.20517/evcna.2024.39	2024
Metabolism	Impact of milk secretor status on the fecal metabolome and microbiota of breastfed infants.	Wang A, Diana A, Rahmannia S, Gibson RS, Houghton LA, Slupsky CM.	Gut Microbes	10.1080/19490976.2023.2257273	2023
	Effects of Probiotic Supplementation on Depressive Symptoms, Sleep Quality, and Modulation of Gut Microbiota and Inflammatory Biomarkers: A Randomized Controlled Trial.	Ahmad SR, AlShahrani AM, Kumari A.	Brain Sci	10.3390/brainsci15070761	2025
	Evaluating the Impact of Probiotic Therapy on the Endocannabinoid System, Pain, Sleep and Fatigue: A Randomized, Double-Blind, Placebo-Controlled Trial in Dancers.	Wiacek J, Podgorski T, Kusy K, Loniewski I, Skonieczna-Zydecka K, Karolkiewicz J.	Int J Mol Sci	10.3390/ijms25115611	2024
Metabolism	Mechanistic insights into the structure-dependant and strain-specific utilization of wheat arabinoxylan by Bifidobacterium longum.	Song AX, Li LQ, Yin JY, Chiou JC, Wu JY.	Carbohydr Polym	10.1016/j.carbpol.2020.116886	2020
	Microplastics and probiotics: Mechanisms of interaction and their consequences for health.	Demarquoy J.	AIMS Microbiol	10.3934/microbiol.2025018	2025
Pathogenicity	Improvement of the inflammation-damaged intestinal barrier and modulation of the gut microbiota in ulcerative colitis after FMT in the SHIME® model.	Kamlarova A, Kvakova M, Ambro L, Link R, Bertkova I, Hertelyova Z, Janicko M, Hijova E, Stofilova J.	BMC Complement Med Ther	10.1186/s12906-025-04889-9	2025
	Bifidobacterium adolescentis CCFM1447 effectively alleviates osteoporosis by enriching intestinal flora capable of vitamin D conversion.	Yu X, Tian G, Wang Y, Li L, Huang L, Zhao Y, Feng L, Zhao Y, Fang H, Lu W, Lu S, Wang H.	Front Nutr	10.3389/fnut.2025.1647671	2025
	Effect of Motiflor AS probiotic for oral health on cell viability in human gingival fibroblasts and human dental pulp stem cells.	Elgun T, Merdan YE.	J Conserv Dent Endod	10.4103/jcde.jcde_125_23	2023
	Gut microbiota shapes cancer immunotherapy responses.	Lei W, Zhou K, Lei Y, Li Q, Zhu H.	NPJ Biofilms Microbiomes	10.1038/s41522-025-00786-8	2025
	Inulin supplementation exhibits increased muscle mass via gut-muscle axis in children with obesity: double evidence from clinical and in vitro studies.	Visuthranukul C, Leelahavanichkul A, Tepaamorndech S, Chamni S, Mekangkul E, Chomtho S.	Sci Rep	10.1038/s41598-024-61781-1	2024
Metabolism	Microbiota dysbiosis impact on the metabolism of T3 and T4 hormones and its association with thyroid cancer.	Cadena-Ullauri S, Guevara-Ramirez P, Paz-Cruz E, Ruiz-Pozo VA, Tamayo-Trujillo R, Zambrano AK.	Front Cell Dev Biol	10.3389/fcell.2025.1589726	2025
	Probiotics and nanoparticle-mediated nutrient delivery in the management of transfusion-supported diseases.	Han W, Xiong N, Huang L.	Front Cell Infect Microbiol	10.3389/fcimb.2025.1575798	2025
Biotechnology	Probiotics formulation and cancer nanovaccines show synergistic effect in immunotherapy and prevention of colon cancer.	Xu X, Zhang M, Liu X, Chai M, Diao L, Ma L, Nie S, Xu M, Wang Y, Mo F, Liu M.	iScience	10.1016/j.isci.2023.107167	2023
Pathogenicity	Bifidobacterium longum, Lactobacillus plantarum and Pediococcus acidilactici Reversed ETEC-Inducing Intestinal Inflammation in Mice.	Li W, Kai L, Jiang Z, He H, Yang M, Su W, Wang Y, Jin M, Lu Z.	Microorganisms	10.3390/microorganisms10122350	2022
	alpha-Amylase inhibition, cytotoxicity and influence of the in vitro gastrointestinal digestion on the bioaccessibility of phenolic compounds in the peel and seed of Theobroma grandiflorum.	Andrade JKS, Barros RGC, Pereira UC, Gualberto NC, de Oliveira CS, Shanmugam S, Narain N.	Food Chem	10.1016/j.foodchem.2021.131494	2022
Pathogenicity	Exogenous acetate mitigates later enhanced allergic airway inflammation in a menopausal mouse model.	Perez Umana ER, Mendes E, Casaro MC, Lazarini M, Oliveira FA, Sperling AI, Ferreira CM.	Front Cell Infect Microbiol	10.3389/fcimb.2025.1543822	2025
Phylogeny	Effects of prenatal bifidobacterium supplementation on the gut microbiome in preterm infants of preeclamptic mothers.	Yin L, Zhao J, Zhou Z, Zhang J, Qu X, Shi J, Yin F.	J Transl Med	10.1186/s12967-025-07296-3	2025
	A ferroptosis-related risk model for non-coding RNA AC002331.1 in colon cancer: construction via competing endogenous RNA network analysis.	Liu J, Zhang C, Ma B, Qi J, Zhang X, Zhao H.	Discov Oncol	10.1007/s12672-025-03351-z	2025
	Exploring the Dose-Effect Relationship of Bifidobacterium longum in Relieving Loperamide Hydrochloride-Induced Constipation in Rats through Colon-Released Capsules.	Zhou X, Mao B, Tang X, Zhang Q, Zhao J, Zhang H, Cui S.	Int J Mol Sci	10.3390/ijms24076585	2023
	Outcome-Specific Efficacy of Different Probiotic Strains and Mixtures in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis.	Xie P, Luo M, Deng X, Fan J, Xiong L.	Nutrients	10.3390/nu15173856	2023
	Design and application of synthetic human gut microbial communities.	Kim MS, Bisanz JE.	Gut Microbes	10.1080/19490976.2025.2575923	2025
	[N-Domain of ArdA Antirestriction Proteins Inhibits the Repression Activity of the Histone-Like H-NS Protein].	Melkina OE, Zavilgelsky GB.	Mol Biol (Mosk)	10.31857/s0026898421030125	2021
	Effect of Probiotics on Uric Acid Levels: Meta-Analysis with Subgroup Analysis and Meta-Regression	Othman R, Sassi M, Hammamia S, Dziri C, Zanina Y, Salem K, Jamoussi H.	Nutrients		2025
	Exploring the Potential of Humoral Immune Response to Commensal Bifidobacterium as a Biomarker for Human Health, including Both Malignant and Non-Malignant Diseases: A Perspective on Detection Strategies and Future Directions.	Itoh K, Matsueda S.	Biomedicines	10.3390/biomedicines12040803	2024
	3'-Sialyllactose and B. infantis synergistically alleviate gut inflammation and barrier dysfunction by enriching cross-feeding bacteria for short-chain fatty acid biosynthesis.	Yang M, Jiang Z, Zhou L, Chen N, He H, Li W, Yu Z, Jiao S, Song D, Wang Y, Jin M, Lu Z.	Gut Microbes	10.1080/19490976.2025.2486512	2025
Metabolism	2'-Fucosyllactose helps butyrate producers outgrow competitors in infant gut microbiota simulations.	Versluis DM, Schoemaker R, Looijesteijn E, Geurts JMW, Merks RMH.	iScience	10.1016/j.isci.2024.109085	2024
Metabolism	Mung Bean Protein Suppresses Undernutrition-Induced Growth Deficits and Cognitive Dysfunction in Rats via Gut Microbiota-TLR4/NF-kB Pathway.	Wei Z, Wang Y, Shi Z, Zhou N, Ren G, Hao X, Zou L, Yao Y.	J Agric Food Chem	10.1021/acs.jafc.1c05220	2021
	Generation of novel prebiotic oligosaccharide pools from fiber drives biological insight in bacterial glycan metabolism.	Masarweh C, Maldonado-Gomez M, Paviani B, Bhattacharya M, Weng C-Y, Suarez C, Ehlers-Cheang S, Stacy A, Castillo J, Krishnakumar N, Kalanetra KA, Barile D, German JB, Lebrilla CB, Mills DA.	Appl Environ Microbiol	10.1128/aem.02077-24	2025
	Fabrication of fish gelatin / sodium alginate double network gels for encapsulation of probiotics.	Liu J, Liu F, Ren T, Wang J, Yang M, Yao Y, Chen H.	J Sci Food Agric	10.1002/jsfa.11081	2021
	Pathologic complete response to chemoimmunotherapy of an advanced gastric cancer patient with high PD-L1 expression, dMMR, and unique gut microbiota composition: A case report.	Jiang H, Wang J, Deng W.	Front Oncol	10.3389/fonc.2023.1150931	2023
	Effect of Probiotics on Sperm Quality in the Adult Mouse.	Sanchez-Rodriguez A, Idrovo IID, Villafranca R, Latorre N, Rielo JA, Laburu A, Nieto-Roman S, Heredia D, Gonzalez R, Garcia-Canas V, Laxalde D, Simo C, Vieites DR, Roldan ERS.	Probiotics Antimicrob Proteins	10.1007/s12602-024-10388-z	2025
	Purple-Grain Wheat Regulation of Blood Lipids and Blood Glucose in Diet-Induced Hyperlipidemic Mice and Type 2 Diabetic Mice.	Hu D, Cheng S, Wei X, Man C.	Nutrients	10.3390/nu17081310	2025
	The Effect of Kefir Consumption on Blood Pressure and C-Reactive Protein: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.	Rashidbeygi E, Samarin MM, Sheikhhossein F, Khalilkhaneh AH, Gholizadeh M, Lohrasbi N, Abbasi A, Bazyar H, Askari G, Amini MR.	Endocrinol Diabetes Metab	10.1002/edm2.70124	2025
Metabolism	Bifidobacterium infantis utilizes N-acetylglucosamine-containing human milk oligosaccharides as a nitrogen source.	Li S, You X, Rani A, Ozcan E, Sela DA.	Gut Microbes	10.1080/19490976.2023.2244721	2023
	Maillard reaction products from Tilapia (Oreochromis mossambicus) scale collagen peptides conjugated with Galactooligosaccharides of different purities: Characterization, antioxidant activity, and impact on the growth of probiotics.	Liu Z, Chen B, Wang S, Xiao Z, Guo H, Wang Z, Qi X, Dong S, Zhao Z.	Food Chem X	10.1016/j.fochx.2025.102733	2025
	Bifidobacterium longum 1714 improves sleep quality and aspects of well-being in healthy adults: a randomized, double-blind, placebo-controlled clinical trial.	Patterson E, Tan HTT, Groeger D, Andrews M, Buckley M, Murphy EF, Groeger JA.	Sci Rep	10.1038/s41598-024-53810-w	2024
Biotechnology	Development of Delivery Systems with Prebiotic and Neuroprotective Potential of Industrial-Grade Cannabis sativa L.	Sip S, Stasilowicz-Krzemien A, Sip A, Szulc P, Neumann M, Kryszak A, Cielecka-Piontek J.	Molecules	10.3390/molecules29153574	2024
	Genetically engineered bacteria-based nanocomposite synergistic HIFU for tumor therapy by changing the acoustic environment of tumor tissues	Gong T, Zhao W, Chen Y, He Y, Xiong J, Xiong Y, Yin L, Luo Y, Tang Y.	Cancer Cell Int		2025
	Preliminary study on BRICS sequential therapeutic regimen as salvage treatment for refractory advanced colorectal cancer patients harboring pMMR status.	Peng Y, Wang J, Wang J, Chen J.	Front Immunol	10.3389/fimmu.2025.1670812	2025
	Exploring the Potential of Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 as Promising Psychobiotics Using SHIME.	De Oliveira FL, Salgaco MK, de Oliveira MT, Mesa V, Sartoratto A, Peregrino AM, Ramos WS, Sivieri K.	Nutrients	10.3390/nu15061521	2023
	MiCK: a database of gut microbial genes linked with chemoresistance in cancer patients.	Shahzaib M, Muaz M, Zubair MH, Kayani MUR.	Database (Oxford)	10.1093/database/baae124	2024
Genetics	Diet-Gut Microbiota Relations: Critical Appraisal of Evidence From Studies Using Metagenomics.	Lotankar M, Houttu N, Mokkala K, Laitinen K.	Nutr Rev	10.1093/nutrit/nuae192	2025
	In vitro ruminal fermentation and cow-to-mouse fecal transplantations verify the inter-relationship of microbiome and metabolome biomarkers: potential to promote health in dairy cows.	Hsieh JC, Chuang ST, Hsu YT, Ho ST, Li KY, Chou SH, Chen MJ.	Front Vet Sci	10.3389/fvets.2023.1228086	2023
	Probiotic Supplements Effect on Feeding Tolerance, Growth and Neonatal Morbidity in Extremely Preterm Infants: A Systematic Review and Meta-Analysis.	Soderquist Kruth S, Persad E, Rakow A.	Nutrients	10.3390/nu17071228	2025
	Effects of Queso Blanco cheese containing Bifidobacterium longum KACC 91563 on fecal microbiota, metabolite and serum cytokine in healthy beagle dogs.	Park HE, Kim YJ, Kim M, Kim H, Do KH, Kim JK, Ham JS, Lee WK.	Anaerobe	10.1016/j.anaerobe.2020.102234	2020
Genetics	Metagenomics reveals functional profiles of gut microbiota during the recovery phase of acute pancreatitis.	Song X, Li JN, Wang D, Han ZY, Yan XX, Yang ZH, Xu J, Wang Q, Wu D.	Sci Rep	10.1038/s41598-025-05127-5	2025
Phylogeny	Multi-omics analysis reveals gut microbial and metabolic signatures in metabolic dysfunction-associated steatotic liver disease.	Maimaitiyiming M, Maihemuti S, Aierken T, Abulimiti G, Aibaidula T, Guan Y, Simayi A, Aimaiti M, Wang X, Abuduaini A, Aishan Y.	Front Microbiol	10.3389/fmicb.2025.1666110	2025
	The effect of Miya on skeletal muscle changes by regulating gut microbiota in rats with osteoarthritis through AMPK pathway.	Wang S, Duan Z, Li Z, Yang D, Lu H, Zhang Y, Fu Y, Guan Y, Li G, Qian F, Xu T.	BMC Musculoskelet Disord	10.1186/s12891-024-08203-5	2024
	Seeding the Infant Gut in Early Life-Effects of Maternal and Infant Seeding with Probiotics on Strain Transfer, Microbiota, and Gastrointestinal Symptoms in Healthy Breastfed Infants.	Melsaether C, Hotoft D, Wellejus A, Hermes GDA, Damholt A.	Nutrients	10.3390/nu15184000	2023
	Milk phospholipids protect Bifidobacterium longum subsp. infantis during in vitro digestion and enhance polysaccharide production.	Kosmerl E, Gonzalez-Orozco BD, Garcia-Cano I, Ortega-Anaya J, Jimenez-Flores R.	Front Nutr	10.3389/fnut.2023.1194945	2023
	The Effects of 12-Week Prebiotic Supplementation on General Wellness and Exercise-Induced Gastrointestinal Symptoms in Recreationally Trained Endurance Athletes: A Triple-Blind Randomised Controlled Pilot Trial.	Gough LA, Weldon A, Clark CCT, Young A, Roberts CJ, Clarke ND, Brown MA, Williams R.	Nutrients	10.3390/nu17213390	2025
	The biofilm-forming ability of six Bifidobacterium strains on grape seed flour	Liu Z, Li L, Fang Z, Lee Y, Zhao J, Zhang H, Chen W, Li H, Lu W.	Lebensm Wiss Technol		2021
	In-depth Microbiological Characterization of Urine From Subjects With Type 2 Diabetes.	Calvigioni M, Biancalana E, Mazzantini D, Celandroni F, Rossi C, Mengozzi A, Ghelardi E, Solini A.	J Clin Endocrinol Metab	10.1210/clinem/dgae389	2024
Pathogenicity	Oral Probiotic Bifidobacterium Longum Supplementation Improves Metabolic Parameters and Alters the Expression of the Renin-Angiotensin System in Obese Mice Liver.	Machado AS, Oliveira JR, Lelis DF, de Paula AMB, Guimaraes ALS, Andrade JMO, Brandi IV, Santos SHS.	Biol Res Nurs	10.1177/1099800420942942	2021
	Multiomics approach reveals the comprehensive interactions between nutrition and children's gut microbiota, and microbial and host metabolomes.	Zhu M, Wang Q, Yang Y, Liu X, Zhang J, Li G, Liu W, Xiang X, Chen J.	Nutr J	10.1186/s12937-025-01116-6	2025
	Effectiveness of Probiotic Use in Alleviating Symptoms of Irritable Bowel Syndrome: A Systematic Review.	Umeano L, Iftikhar S, Alhaddad SF, Paulsingh CN, Riaz MF, Garg G, Mohammed L.	Cureus	10.7759/cureus.58306	2024
	The dual role for probiotics use in dental practices.	Goff DA, McFarland LV, Johnson S, Goff DW.	Front Oral Health	10.3389/froh.2023.1336565	2023
	Effects of dietary fiber on the composition, function, and symbiotic interactions of intestinal microbiota in pre-weaned calves.	Lu W, Yi X, Ge Y, Zhang X, Shen K, Zhuang H, Deng Z, Liu D, Cao J, Ma C.	Front Microbiol	10.3389/fmicb.2025.1554484	2025
	Probiotics to prevent necrotizing enterocolitis in very low birth weight infants: A network meta-analysis.	Zhou KZ, Wu K, Deng LX, Hu M, Luo YX, Zhang LY.	Front Pediatr	10.3389/fped.2023.1095368	2023
Genetics	Metagenomic Characterisation of the Gut Microbiome and Effect of Complementary Feeding on Bifidobacterium spp. in Australian Infants.	Parkin K, Palmer DJ, Verhasselt V, Amenyogbe N, Cooper MN, Christophersen CT, Prescott SL, Silva D, Martino D.	Microorganisms	10.3390/microorganisms12010228	2024
	The effect of culturing temperature on the growth of the most dominant bacterial species of human gut microbiota and harmful bacterial species.	Shimokawa H, Sakakibara H, Ami Y, Hirano R, Kurihara S.	Biosci Microbiota Food Health	10.12938/bmfh.2024-087	2025
	Probiotics ameliorate endocrine disorders via modulating inflammatory pathways: a systematic review.	Nemati M, Ebrahimi B, Montazeri-Najafabady N.	Genes Nutr	10.1186/s12263-024-00743-8	2024
	Long-term alterations in gut microbiota following mild COVID-19 recovery: bacterial and fungal community shifts.	Li D, Zhang DY, Chen SJ, Lv YT, Huang SM, Chen C, Zeng F, Chen RX, Zhang XD, Xiong JX, Chen FD, Jiang YH, Chen Z, Mo CY, Chen JJ, Zhu XL, Zhang LJ, Bai FH.	Front Cell Infect Microbiol	10.3389/fcimb.2025.1565887	2025
	Adjunctive efficacy of Bifidobacterium animalis subsp. lactis XLTG11 for functional constipation in children.	Chen K, Zhou Z, Nie Y, Cao Y, Yang P, Zhang Y, Xu P, Yu Q, Shen Y, Ma W, Jin S, Liu C.	Braz J Microbiol	10.1007/s42770-024-01276-3	2024
	Usefulness of Bifidobacterium longum BB536 in Elderly Individuals With Chronic Constipation: A Randomized Controlled Trial.	Takeda T, Asaoka D, Nojiri S, Yanagisawa N, Nishizaki Y, Osada T, Koido S, Nagahara A, Katsumata N, Odamaki T, Xiao JZ, Ohkusa T, Sato N.	Am J Gastroenterol	10.14309/ajg.0000000000002028	2023
	Studies of the Impact of the Bifidobacterium Species on Inducible Nitric Oxide Synthase Expression and Nitric Oxide Production in Murine Macrophages of the BMDM Cell Line.	Zablocka A, Jakubczyk D, Leszczynska K, Pacyga-Prus K, Macala J, Gorska S.	Probiotics Antimicrob Proteins	10.1007/s12602-023-10093-3	2024
	Impact of Bifidobacterium longum Subspecies infantis on Pediatric Gut Health and Nutrition: Current Evidence and Future Directions.	Dargenio VN, Cristofori F, Brindicci VF, Schettini F, Dargenio C, Castellaneta SP, Iannone A, Francavilla R.	Nutrients	10.3390/nu16203510	2024
	Metabolome-associated psychological comorbidities improvement in irritable bowel syndrome patients receiving a probiotic.	Martin FP, Cominetti O, Berger B, Combremont S, Marquis J, Xie G, Jia W, Pinto-Sanchez MI, Bercik P, Bergonzelli G.	Gut Microbes	10.1080/19490976.2024.2347715	2024
Pathogenicity	Gut microbiota alterations and their association with tumorigenic pathways in colorectal cancer: insights from a pooled analysis of 109 microbiome datasets.	Haque S, Bantun F, Jalal NA, Faidah H, Babalghith AO, Alobaidy MA, Aldairi AF, Ahmad F.	Gut Pathog	10.1186/s13099-025-00712-5	2025
Metabolism	Bifidobacterium longum DS0956 and Lactobacillus rhamnosus DS0508 culture-supernatant ameliorate obesity by inducing thermogenesis in obese-mice.	Hossain M, Park DS, Rahman MS, Ki SJ, Lee YR, Imran KM, Yoon D, Heo J, Lee TJ, Kim YS.	Benef Microbes	10.3920/bm2019.0179	2020
	Supercharged NK cells: a unique population of NK cells capable of differentiating stem cells and lysis of MHC class I high differentiated tumors	Kaur K, Chen P, Jewett A.	Cell Death Dis		2025
	Analysis of Antibiotic Resistance Genes in Water Reservoirs and Related Wastewater from Animal Farms in Central China.	Rui Y, Qiu G.	Microorganisms	10.3390/microorganisms12020396	2024
	Comparison of the Gut Microbiota of Patients Who Improve with Antibiotic Combination Therapy for Ulcerative Colitis and Those Who Do Not: Investigation by Fecal Metagenomic Analyses.	Ohkusa T, Kato K, Sekizuka T, Sugiyama T, Sato N, Kuroda M.	Nutrients	10.3390/nu16203500	2024
	The role of Bifidobacterium in longevity and the future of probiotics.	Ku S, Haque MA, Jang MJ, Ahn J, Choe D, Jeon JI, Park MS.	Food Sci Biotechnol	10.1007/s10068-024-01631-y	2024
	Nutrition is Associated with Violent and Criminal Behaviors	Asil E, Erkmen E.	Curr Nutr Rep		2025
	Two extracellular alpha-arabinofuranosidases are required for cereal-derived arabinoxylan metabolism by Bifidobacterium longum subsp. longum.	Friess L, Bottacini F, McAuliffe FM, O'Neill IJ, Cotter PD, Lee C, Munoz-Munoz J, van Sinderen D.	Gut Microbes	10.1080/19490976.2024.2353229	2024
	Dynamics of Active Fluorescent Units (AFU) and Water Activity (a_w) Changes in Probiotic Products-Pilot Study.	Sielatycka K, Sliwa-Dominiak J, Radaczynska M, Juzwa W, Kaczmarczyk M, Marlicz W, Skonieczna-Zydecka K, Loniewski I.	Foods	10.3390/foods12214018	2023
Pathogenicity	Next-generation probiotics and engineered BEVs for precision therapeutics in osteoporosis.	Wei J, Ding W, Song K, Zhang Y, Luo Q, Qi C.	Front Nutr	10.3389/fnut.2025.1581971	2025
	Prebiotics, Probiotics, and Synbiotics-A Research Hotspot for Pediatric Obesity.	Borka Balas R, Melit LE, Lupu A, Lupu VV, Marginean CO.	Microorganisms	10.3390/microorganisms11112651	2023
	Synbiotic Supplementation with Probiotics and Omega-3 Fatty Acids Enhances Upper-Body Muscle Strength in Elite Swimmers: Evidence for Gut-Muscle Axis Modulation During Race-Pace Training.	Imanian B, Hemmatinafar M, Maymandinejad I, Binazade MR, Jager R, Jahan Z, Naseri K, Rezaei R, Suzuki K.	Nutrients	10.3390/nu17182959	2025
	Influence of the pili of Lacticaseibacillus rhamnosus GG on its encapsulation and survival in mixed protein-starch gels assembled by in situ fermentation.	Hernandez-Barrueta T, Amaya-Llano SL, Nitin N.	Appl Environ Microbiol	10.1128/aem.00248-25	2025
	Study of Potential Synergistic Effect of Probiotic Formulas on Acrylamide Reduction.	Choi SM, Lin H, Xie W, Chu IK.	Int J Mol Sci	10.3390/ijms24054693	2023
	Synergistic Inhibition of Candida albicans by Cranberry Proanthocyanidins and Probiotics: Novel Strategies for Vulvovaginal Candidiasis Treatment.	Wu YR, Chen JS, Chen LC, Chen L, Huang YF, Liao CS.	Pathogens	10.3390/pathogens14040308	2025
Pathogenicity	Role of Lactiplantibacillus plantarum UBLP-40, Lactobacillus rhamnosus UBLR-58 and Bifidobacterium longum UBBL-64 in the Wound Healing Process of the Excisional Skin.	Panagiotou D, Filidou E, Gaitanidou M, Tarapatzi G, Spathakis M, Kandilogiannakis L, Stavrou G, Arvanitidis K, Tsetis JK, Gionga P, Shrewsbury AD, Manolopoulos VG, Kapoukranidou D, Lasithiotakis K, Kolios G, Kotzampassi K.	Nutrients	10.3390/nu15081822	2023
	Impact of the microbiome on tumor immunity.	McCoy KD, Mager LF.	Curr Opin Immunol	10.1016/j.coi.2021.01.002	2021
	Bifidobacterium longum BORI inhibits pain behavior and chondrocyte death, and attenuates osteoarthritis progression.	Oh DK, Na HS, Jhun JY, Lee JS, Um IG, Lee SY, Park MS, Cho ML, Park SH.	PLoS One	10.1371/journal.pone.0286456	2023
	Fecal microbiome analysis in patients with metabolic syndrome and type 2 diabetes.	Sinisterra Loaiza LI, Fernandez-Edreira D, Linares-Blanco J, Cepeda A, Cardelle-Cobas A, Fernandez-Lozano C.	PeerJ	10.7717/peerj.19108	2025
	Microbiome features associated with performance measures in athletic and non-athletic individuals: A case-control study.	Huminska-Lisowska K, Zielinska K, Mieszkowski J, Michalowska-Sawczyn M, Cieszczyk P, Labaj PP, Wasag B, Fraczek B, Grzywacz A, Kochanowicz A, Kosciolek T.	PLoS One	10.1371/journal.pone.0297858	2024
	Antidiabetic effects of selenium-enriched Bifidobacterium longum DD98 in type 2 diabetes model of mice.	Zhao D, Zhu H, Gao F, Qian Z, Mao W, Yin Y, Tan J, Chen D.	Food Funct	10.1039/d0fo00180e	2020
	Synergistic Effects of Probiotic and Omega-3 Supplementation with Ultra-Short Race Pace Training on Sprint Swimming Performance.	Maymandinejad I, Hemmatinafar M, Jager R, Imanian B, Koushkie Jahromi M, Suzuki K.	Nutrients	10.3390/nu17142296	2025
	Gut microbiome links obesity to type 2 diabetes: insights from Mendelian randomization.	Fu L, Baranova A, Cao H, Zhang F.	BMC Microbiol	10.1186/s12866-025-03968-8	2025
	Efficacy and Safety of a Mixture of Microencapsulated Sodium Butyrate, Probiotics, and Short Chain Fructooligosaccharides in Patients with Irritable Bowel Syndrome-A Randomized, Double-Blind, Placebo-Controlled Study.	Gasiorowska A, Romanowski M, Walecka-Kapica E, Kaczka A, Chojnacki C, Padysz M, Siedlecka M, Banasik J, Sobolewska-Wlodarczyk A, Wisniewska-Jarosinska M, Bierla JB, Otaru N, Cukrowska B, Steinert RE.	J Clin Med	10.3390/jcm14010006	2024
	Microbiota boost immunotherapy? A meta-analysis dives into fecal microbiota transplantation and immune checkpoint inhibitors.	Lin A, Huang L, Jiang A, Zhu L, Mou W, Li Y, Zhang C, Liu Z, Zhang J, Cheng Q, Wei T, Luo P.	BMC Med	10.1186/s12916-025-04183-y	2025
	Total Transit Time and Probiotic Persistence in Healthy Adults: A Pilot Study.	Tremblay A, Auger J, Alyousif Z, Calero SEC, Mathieu O, Rivero-Mendoza D, Elmaoui A, Dahl WJ, Tompkins TA.	J Neurogastroenterol Motil	10.5056/jnm22031	2023
	Probiotics and Human Milk Differentially Influence the Gut Microbiome and NEC Incidence in Preterm Pigs.	Melendez Hebib V, Taft DH, Stoll B, Liu J, Call L, Guthrie G, Jensen N, Hair AB, Mills DA, Burrin DG.	Nutrients	10.3390/nu15112585	2023
	Metabolic Status Influences Probiotic Efficacy for Depression-PRO-DEMET Randomized Clinical Trial Results.	Gawlik-Kotelnicka O, Margulska A, Pleska K, Skowronska A, Strzelecki D.	Nutrients	10.3390/nu16091389	2024
	The Effect of the Ideal Food Pyramid on Gut Microbiota in Rheumatoid Arthritis Patients.	Kacar Mutluturk U, Cicek B, Cengiz G.	Life (Basel)	10.3390/life15030463	2025
	Implications of the gut microbiome in spinal cord injuries.	Jeyaraman N, Jeyaraman M, Dhanabal P, Ramasubramanian S, Ambrosio L, Vadala G, Muthu S.	Front Surg	10.3389/fsurg.2025.1668225	2025
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Metabolism	A cold-active 1,4-alpha-glucan branching enzyme from Bifidobacterium longum reduces the retrogradation and enhances the slow digestibility of wheat starch.	Li D, Fei T, Wang Y, Zhao Y, Dai L, Fu X, Li X.	Food Chem	10.1016/j.foodchem.2020.126855	2020
Pathogenicity	Selenium-enriched Bifidobacterium longum protected alcohol and high fat diet induced hepatic injury in mice.	Yi HW, Zhu XX, Huang XL, Lai YZ, Tang Y.	Chin J Nat Med	10.1016/s1875-5364(20)30018-2	2020
	Associations between gut microbiota and sarcopenia or its defining parameters in older adults: A systematic review.	Lapauw L, Rutten A, Dupont J, Amini N, Vercauteren L, Derrien M, Raes J, Raes J, Gielen E.	J Cachexia Sarcopenia Muscle	10.1002/jcsm.13569	2024
	Early-life gut microbiota in food allergic children and its impact on the development of allergic disease.	Yan X, Yan J, Xiang Q, Dai H, Wang Y, Fang L, Huang K, Zhang W.	Ital J Pediatr	10.1186/s13052-023-01557-x	2023
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Genetics	Metagenomic Microbial Signatures for Noninvasive Detection of Pancreatic Cancer.	Chen Y, Nian F, Chen J, Jiang Q, Yuan T, Feng H, Shen X, Dong L.	Biomedicines	10.3390/biomedicines13041000	2025
Metabolism	Effect of supplemental prebiotics, probiotics and bioactive proteins on the microbiome composition and fecal calprotectin in C57BL6/j mice.	Li Y, Hintze KJ, Ward RE.	Biochimie	10.1016/j.biochi.2021.02.010	2021
	Evaluation of the gut microbiome associated with COVID-19.	Maddah R, Goodarzi V, Asadi-Yousefabad SL, Abbasluo M, Shariati P, Shafiei Kafraj A.	Inform Med Unlocked	10.1016/j.imu.2023.101239	2023
	Gut-brain axis in post-traumatic stress disorder: microbial - mediated mechanisms and new therapeutic approaches - A narrative review.	Pan J, Lin S, Qian Q, Fu S, Liu X.	Front Pharmacol	10.3389/fphar.2025.1621678	2025
	Comparison of Rifaximin Monotherapy and Rifaximin Combined with Probiotics in Patients with Irritable Bowel Syndrome: A Randomized Controlled Trial.	Oh CK, Chung HH, Kim YJ, Kim JB.	Nutrients	10.3390/nu17050763	2025
	Analysis of the Beneficial Effects of Probiotics on the Gut-Prostate Axis Using Prostatic Co-Culture Model.	Ferrari S, Galla R, Mule S, Uberti F.	Foods	10.3390/foods13223647	2024
	Association of Gut Microbiome with Muscle Mass, Muscle Strength, and Muscle Performance in Older Adults: A Systematic Review.	Mayer MH, Woldemariam S, Gisinger C, Dorner TE.	Int J Environ Res Public Health	10.3390/ijerph21091246	2024
	Human milk oligosaccharides combine with Bifidobacterium longum to form the "golden shield" of the infant intestine: metabolic strategies, health effects, and mechanisms of action.	Yang S, Cai J, Su Q, Li Q, Meng X.	Gut Microbes	10.1080/19490976.2024.2430418	2024
	Assessment of In Ovo Administration of Bifidobacterium bifidum and Bifidobacterium longum on Performance, Ileal Histomorphometry, Blood Hematological, and Biochemical Parameters of Broilers.	El-Moneim AEEA, El-Wardany I, Abu-Taleb AM, Wakwak MM, Ebeid TA, Saleh AA.	Probiotics Antimicrob Proteins	10.1007/s12602-019-09549-2	2020
	Efficacy of probiotic co-supplementation with omega-3 PUFAs on pancreatic beta-cell function in type 2 diabetes.	Savytska M, Kyriienko D, Mykhalchyshyn G, Tsyryuk O, Falalyeyeva T, Kobyliak N.	Sci Rep	10.1038/s41598-025-07861-2	2025
	Understanding the link between gut microbiota, dietary intake, and nutritional status in children with autism and typical development.	Mendive Dubourdieu P, Guerendiain M.	Front Nutr	10.3389/fnut.2023.1202948	2023
	Acerola by-product may improve the in vitro gastrointestinal resistance of probiotic strains in a plant-based fermented beverage	Vieira ADS, Battistini C, Bedani R, Saad SMI.	Lebensm Wiss Technol	10.1016/j.lwt.2021.110858	2021
	Plant-based dietary index in relation to gut microbiota in Arab women.	Aljuraiban GS, Aljazairy EA, Alsahli AS, Sabico S, Al-Musharaf S.	Medicine (Baltimore)	10.1097/md.0000000000035262	2023
Pathogenicity	Study on the regulatory effects and mechanisms of action of bifidobacterial exopolysaccharides on anaphylaxes in mice.	Luo M, Gan M, Yu X, Wu X, Xu F.	Int J Biol Macromol	10.1016/j.ijbiomac.2020.09.224	2020
Metabolism	Effect of inactivated Bifidobacterium longum intake on obese diabetes model mice (TSOD).	Ben Othman M, Sakamoto K.	Food Res Int	10.1016/j.foodres.2019.108792	2020
	The effect of probiotics and casein supplementation on aerobic capacity parameters of male soccer players.	Imanian B, Hemmatinafar M, Daryanoosh F, Koureshfard N, Sadeghi R, Niknam A, Rezaei R, Qashqaei A.	J Int Soc Sports Nutr	10.1080/15502783.2024.2382165	2024
Metabolism	Bifidobacterium longum subsp. longum Remodeled Roseburia and Phosphatidylserine Levels and Ameliorated Intestinal Disorders and liver Metabolic Abnormalities Induced by High-Fat Diet.	Wu T, Wu T, Sun M, Liu R, Sui W, Zhang J, Yin J, Fang S, Zhu J, Zhang M.	J Agric Food Chem	10.1021/acs.jafc.0c00717	2020
	A Review on the Protective Effects of Probiotics against Alzheimer's Disease.	Mishra V, Yadav D, Solanki KS, Koul B, Song M.	Biology (Basel)	10.3390/biology13010008	2023
	Immunomodulatory Effects by Bifidobacterium longum KACC 91563 in Mouse Splenocytes and Macrophages.	Choi M, Lee Y, Lee NK, Bae CH, Park DC, Paik HD, Park E.	J Microbiol Biotechnol	10.4014/jmb.1812.12002	2019
	Effect of the Darolac^® (Oralis SB^®) Probiotic Formulation on Oral Health: A Narrative Review.	Blais L, Auclair-Ouellet N, Tremblay A, Binda S.	Microorganisms	10.3390/microorganisms13020408	2025
	Enteral supplementation with probiotics in preterm infants: A retrospective cohort study and 6-year follow-up.	Brown BE, Huisman E, Miller MR, Ulrich C, Reid G, da Silva O.	Front Nutr	10.3389/fnut.2022.1063121	2022
Metabolism	Metabarcoding analysis of gut microbiota of healthy individuals reveals impact of probiotic and maltodextrin consumption.	Calgaro M, Pandolfo M, Salvetti E, Marotta A, Larini I, Pane M, Amoruso A, Del Casale A, Vitulo N, Fiorio M, Felis GE.	Benef Microbes	10.3920/bm2020.0137	2021
	Exploring the Relationship between MicroRNAs, Intratumoral Microbiota, and Breast Cancer Progression in Patients with and without Metastasis.	Laborda-Illanes A, Aranega-Martin L, Sanchez-Alcoholado L, Boutriq S, Plaza-Andrades I, Peralta-Linero J, Garrido Ruiz G, Pajares-Hachero B, Alvarez M, Alba E, Gonzalez-Gonzalez A, Queipo-Ortuno MI.	Int J Mol Sci	10.3390/ijms25137091	2024
	Management of Neonates in the Special Care Nursery and Its Impact on the Developing Gut Microbiota: A Comprehensive Clinical Review	Srinivasjois R, Rao S, Pereira G.	Microorganisms		2025
Enzymology	Human Bifidobacterium strains as adjunct cultures in Spanish sheep milk cheese.	Langa S, Peiroten A, Gaya P, Garde S, Arques JL, Nunez M, Medina M, Rodriguez-Minguez E.	J Dairy Sci	10.3168/jds.2020-18203	2020
	Microbiota Modulation of Radiosensitiveness and Toxicity in Gastrointestinal Cancers: What Radiation Oncologists Need to Know-A Review on Behalf of the Italian Association of Radiobiology (AIRB).	Bonu ML, Georgopulos A, Ramera M, Andreuccetti J, Guerini AE, Bozzola AM, Morelli V, Balduzzi J, Katica M, Cefaratti M, Granello L, Triggiani L, Buglione M, Magrini SM, Marampon F, Mondini M, Parisi S, Timon G, Bellu L, Rescigno M, Arcangeli S, Scorsetti M.	Curr Issues Mol Biol	10.3390/cimb47040265	2025
	Crosstalk Between Microbiome and Ferroptosis in Diseases: From Mechanism to Therapy.	Ding SQ, Lei Y, Zhao ZM, Li XY, Lang JX, Zhang JK, Li YS, Zhang CD, Dai DQ.	Compr Physiol	10.1002/cph4.70042	2025
	Aging characteristics of colorectal cancer based on gut microbiota.	Wu Y, Zhuang J, Zhang Q, Zhao X, Chen G, Han S, Hu B, Wu W, Han S.	Cancer Med	10.1002/cam4.6414	2023
	Comprehensive insights from composition to functional microbe-based biodiversity of the infant human gut microbiota.	Lugli GA, Mancabelli L, Milani C, Fontana F, Tarracchini C, Alessandri G, van Sinderen D, Turroni F, Ventura M.	NPJ Biofilms Microbiomes	10.1038/s41522-023-00392-6	2023
	Comparative effects of non-fermented and Lacticaseibacillus paracasei-fermented pomelo juice on gut microbiota composition and short-chain fatty acid production: An in vitro colonic model.	Balmori V, Marnpae M, Kamonsuwan K, Chusak C, Nungarlee U, Sivapornnukul P, Chanchaem P, Payungporn S, Charoensiddhi S, Suantawee T, Thilavech T, Adisakwattana S.	Food Chem X	10.1016/j.fochx.2024.102041	2024
	Bifidobacterium longum subsp. longum Reduces Perceived Psychological Stress in Healthy Adults: An Exploratory Clinical Trial.	Boehme M, Remond-Derbez N, Lerond C, Lavalle L, Keddani S, Steinmann M, Rytz A, Dalile B, Verbeke K, Van Oudenhove L, Steiner P, Berger B, Vicario M, Bergonzelli G, Colombo Mottaz S, Hudry J.	Nutrients	10.3390/nu15143122	2023
	Bifidobacterium longum subsp. infantis CECT 7210 Reduces Inflammatory Cytokine Secretion in Caco-2 Cells Cultured in the Presence of Escherichia coli CECT 515.	Alvarez-Mercado AI, Plaza-Diaz J, de Almagro MC, Gil A, Moreno-Munoz JA, Fontana L.	Int J Mol Sci	10.3390/ijms231810813	2022
	Identification of core gene-gut microbiome associations in diverticulitis patients through a two-sample mendelian randomization and bioinformatics-based investigation.	Hao W, Wang Z, Ma H.	Glob Med Genet	10.1016/j.gmg.2025.100065	2025
	Clinical efficacy of probiotic supplementation in the treatment of knee osteoarthritis: a meta-analysis.	Tian M, Zhu Y, Lu S, Qin Y, Li X, Wang T, Guo Y, Shi H, Qin D.	Front Microbiol	10.3389/fmicb.2025.1526690	2025
	Putative Probiotic Strains Isolated from Kefir Improve Gastrointestinal Health Parameters in Adults: a Randomized, Single-Blind, Placebo-Controlled Study.	Wang MC, Zaydi AI, Lin WH, Lin JS, Liong MT, Wu JJ.	Probiotics Antimicrob Proteins	10.1007/s12602-019-09615-9	2020
Metabolism	Structural analysis of beta-L-arabinobiose-binding protein in the metabolic pathway of hydroxyproline-rich glycoproteins in Bifidobacterium longum.	Miyake M, Terada T, Shimokawa M, Sugimoto N, Arakawa T, Shimizu K, Igarashi K, Fujita K, Fushinobu S.	FEBS J	10.1111/febs.15315	2020
	Tryptophan Metabolism in Neurodevelopment and Its Implications For Neurodevelopmental Disorders.	Giuliano MG, Tognini P.	Mol Neurobiol	10.1007/s12035-025-05437-9	2025
	Unlocking the potential of probiotic administration in caries management: a systematic review.	Lopes PC, Gomes ATPC, Mendes K, Blanco L, Correia MJ.	BMC Oral Health	10.1186/s12903-024-03893-8	2024
	Antioxidant, Anti-Inflammatory, Antagonistic, and Probiotic Properties of Lactic Acid Bacteria Isolated from Traditional Algerian Fermented Wheat	Benguiar R, Benaraba R, Farhat C, Chouchane H, Boughaddou D, Belalem F, Cherif A.	Microorganisms		2025
	Disclosing alpha-lactalbumin impact on the intestinal and vaginal microbiota of women suffering from polycystic ovary syndrome.	Alessandri G, Mancabelli L, Fontana F, Lepore E, Forte G, Burratti M, Ventura M, Turroni F.	Microb Biotechnol	10.1111/1751-7915.14540	2024
	Co-Encapsulation of Probiotics and Prebiotics: Techniques and Applications in Food Fortification.	Shanuke DS, Ranasinghage NBDP, Illippangama AU, Kulathunga J, Bandara MD.	Food Sci Nutr	10.1002/fsn3.70426	2025
	The Tetracycline Resistance Gene, tet(W) in Bifidobacterium animalis subsp. lactis Follows Phylogeny and Differs From tet(W) in Other Species.	Nohr-Meldgaard K, Struve C, Ingmer H, Agerso Y.	Front Microbiol	10.3389/fmicb.2021.658943	2021
Genetics	Mobilome and Resistome Reconstruction from Genomes Belonging to Members of the Bifidobacterium Genus.	Mancino W, Lugli GA, Sinderen DV, Ventura M, Turroni F.	Microorganisms	10.3390/microorganisms7120638	2019
Pathogenicity	Fourier transform infra-red spectroscopy and flow cytometric assessment of the antibacterial mechanism of action of aqueous extract of garlic (Allium sativum) against selected probiotic Bifidobacterium strains.	Booyens J, Thantsha MS.	BMC Complement Altern Med	10.1186/1472-6882-14-289	2014
	Adhesion properties of a putative polymorphic fimbrial subunit protein from Bifidobacterium longum subsp. longum.	Suzuki K, Nishiyama K, Miyajima H, Osawa R, Yamamoto Y, Mukai T.	Biosci Microbiota Food Health	10.12938/bmfh.2015-015	2016
Phylogeny	Investigation of the evolutionary development of the genus Bifidobacterium by comparative genomics.	Lugli GA, Milani C, Turroni F, Duranti S, Ferrario C, Viappiani A, Mancabelli L, Mangifesta M, Taminiau B, Delcenserie V, van Sinderen D, Ventura M.	Appl Environ Microbiol	10.1128/aem.02004-14	2014
Genetics	The comparative genomics of Bifidobacterium callitrichos reflects dietary carbohydrate utilization within the common marmoset gut.	Albert K, Rani A, Sela DA.	Microb Genom	10.1099/mgen.0.000183	2018
Genetics	Pangenome analysis of Bifidobacterium longum and site-directed mutagenesis through by-pass of restriction-modification systems.	O'Callaghan A, Bottacini F, O'Connell Motherway M, van Sinderen D.	BMC Genomics	10.1186/s12864-015-1968-4	2015
Genetics	Bifidobacterium Bacteremia: Clinical Characteristics and a Genomic Approach To Assess Pathogenicity.	Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C, Norwegian Study Group on Invasive Bifidobacterial Infections.	J Clin Microbiol	10.1128/jcm.00150-17	2017
	Linking human milk oligosaccharide metabolism and early life gut microbiota: bifidobacteria and beyond.	Lordan C, Roche AK, Delsing D, Nauta A, Groeneveld A, MacSharry J, Cotter PD, van Sinderen D.	Microbiol Mol Biol Rev	10.1128/mmbr.00094-23	2024
Pathogenicity	Exploring the Ecology of Bifidobacteria and Their Genetic Adaptation to the Mammalian Gut.	Duranti S, Longhi G, Ventura M, van Sinderen D, Turroni F.	Microorganisms	10.3390/microorganisms9010008	2020
	Prevalence of Antibiotic Resistance Genes among Human Gut-Derived Bifidobacteria.	Duranti S, Lugli GA, Mancabelli L, Turroni F, Milani C, Mangifesta M, Ferrario C, Anzalone R, Viappiani A, van Sinderen D, Ventura M.	Appl Environ Microbiol	10.1128/aem.02894-16	2017
Pathogenicity	Effect of Soy Isoflavones on Growth of Representative Bacterial Species from the Human Gut.	Vazquez L, Florez AB, Guadamuro L, Mayo B.	Nutrients	10.3390/nu9070727	2017
Metabolism	Oligosaccharide binding proteins from Bifidobacterium longum subsp. infantis reveal a preference for host glycans.	Garrido D, Kim JH, German JB, Raybould HE, Mills DA.	PLoS One	10.1371/journal.pone.0017315	2011
	Potential of Nanonutraceuticals in Increasing Immunity.	Jampilek J, Kralova K.	Nanomaterials (Basel)	10.3390/nano10112224	2020
Genetics	Comparative genomic and phylogenomic analyses of the Bifidobacteriaceae family.	Lugli GA, Milani C, Turroni F, Duranti S, Mancabelli L, Mangifesta M, Ferrario C, Modesto M, Mattarelli P, Jiri K, van Sinderen D, Ventura M.	BMC Genomics	10.1186/s12864-017-3955-4	2017
	Characterization of GH2 and GH42 beta-galactosidases derived from bifidobacterial infant isolates.	Ambrogi V, Bottacini F, O'Sullivan J, O'Connell Motherway M, Linqiu C, Schoemaker B, Schoterman M, van Sinderen D.	AMB Express	10.1186/s13568-019-0735-3	2019
Genetics	Tracking the Taxonomy of the Genus Bifidobacterium Based on a Phylogenomic Approach.	Lugli GA, Milani C, Duranti S, Mancabelli L, Mangifesta M, Turroni F, Viappiani A, van Sinderen D, Ventura M.	Appl Environ Microbiol	10.1128/aem.02249-17	2018
Metabolism	Ability of bifidobacteria to metabolize chitin-glucan and its impact on the gut microbiota.	Alessandri G, Milani C, Duranti S, Mancabelli L, Ranjanoro T, Modica S, Carnevali L, Statello R, Bottacini F, Turroni F, Ossiprandi MC, Sgoifo A, van Sinderen D, Ventura M.	Sci Rep	10.1038/s41598-019-42257-z	2019
Phylogeny	Genomic encyclopedia of type strains of the genus Bifidobacterium.	Milani C, Lugli GA, Duranti S, Turroni F, Bottacini F, Mangifesta M, Sanchez B, Viappiani A, Mancabelli L, Taminiau B, Delcenserie V, Barrangou R, Margolles A, van Sinderen D, Ventura M.	Appl Environ Microbiol	10.1128/aem.02308-14	2014
Enzymology	Specific identification and targeted characterization of Bifidobacterium lactis from different environmental isolates by a combined multiplex-PCR approach.	Ventura M, Reniero R, Zink R.	Appl Environ Microbiol	10.1128/aem.67.6.2760-2765.2001	2001
	Mixed-species genomic microarray analysis of fecal samples reveals differential transcriptional responses of bifidobacteria in breast- and formula-fed infants.	Klaassens ES, Boesten RJ, Haarman M, Knol J, Schuren FH, Vaughan EE, de Vos WM.	Appl Environ Microbiol	10.1128/aem.02492-08	2009
	Enzymatic lacto-N-biose elongation of human milk oligosaccharides with the GH136 lacto-N-biosidase LnbX engineered for improved transglycosylation.	Vuillemin M, Lengyel M, Muschiol J, Matwiejuk M, Zhang Y, Cannac N, Molnar-Gabor D, Meyer AS, Zeuner B.	Enzyme Microb Technol	10.1016/j.enzmictec.2025.110660	2025
	Bifidobacterial GH146 beta-L-arabinofuranosidase for the removal of beta1,3-L-arabinofuranosides on plant glycans.	Fujita K, Tsunomachi H, Lixia P, Maruyama S, Miyake M, Dakeshita A, Kitahara K, Tanaka K, Ito Y, Ishiwata A, Fushinobu S.	Appl Microbiol Biotechnol	10.1007/s00253-024-13014-8	2024
	Isomaltooligosaccharides utilization and genomic characterization of human infant anti-inflammatory Bifidobacterium longum and Bifidobacterium breve strains.	Sharma S, Singh S, Chaudhary V, Mantri S, Chander A, Maurya R, Rajarammohan S, Singh RP, Rishi P, Bishnoi M, Bhadada SK, Kondepudi KK.	3 Biotech	10.1007/s13205-022-03141-2	2022
	Substrate recognition mode of a glycoside hydrolase family 42 beta-galactosidase from Bifidobacterium longum subspecies infantis (BiBga42A) revealed by crystallographic and mutational analyses.	Gotoh A, Hidaka M, Sakurama H, Nishimoto M, Kitaoka M, Sakanaka M, Fushinobu S, Katayama T.	Microbiome Res Rep	10.20517/mrr.2023.14	2023
	Safety, efficacy, and impact on gut microbial ecology of a Bifidobacterium longum subspecies infantis LMG11588 supplementation in healthy term infants: a randomized, double-blind, controlled trial in the Philippines.	Capeding MRZ, Phee LCM, Ming C, Noti M, Vidal K, Le Carrou G, Frezal A, Moll JM, Vogt JK, Myers PN, Nielsen BH, Boulange CL, Samuel TM, Berger B, Cercamondi CI.	Front Nutr	10.3389/fnut.2023.1319873	2023
	MicroRNAs from edible plants reach the human gastrointestinal tract and may act as potential regulators of gene expression.	Diez-Sainz E, Milagro FI, Aranaz P, Riezu-Boj JI, Lorente-Cebrian S.	J Physiol Biochem	10.1007/s13105-024-01023-0	2024
	Faecal hsa-miR-7704 inhibits the growth and adhesion of Bifidobacterium longum by suppressing ProB and aggravates hepatic encephalopathy.	Wang Y, Li Y, Lv L, Zhu L, Hong L, Wang X, Zhang Y, Wang X, Diao H.	NPJ Biofilms Microbiomes	10.1038/s41522-024-00487-8	2024
	A Novel Bifidobacterium longum Subsp. longum T1 Strain from Cow's Milk: Homeostatic and Antibacterial Activity against ESBL-Producing Escherichia coli.	Machulin AV, Abramov VM, Kosarev IV, Deryusheva EI, Priputnevich TV, Panin AN, Manoyan AM, Chikileva IO, Abashina TN, Blumenkrants DA, Ivanova OE, Papazyan TT, Nikonov IN, Suzina NE, Melnikov VG, Khlebnikov VS, Sakulin VK, Samoilenko VA, Gordeev AB, Sukhikh GT, Uversky VN, Karlyshev AV.	Antibiotics (Basel)	10.3390/antibiotics13100924	2024
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	Revisiting the Metabolic Capabilities of Bifidobacterium longum susbp. longum and Bifidobacterium longum subsp. infantis from a Glycoside Hydrolase Perspective.	Blanco G, Ruiz L, Tames H, Ruas-Madiedo P, Fdez-Riverola F, Sanchez B, Lourenco A, Margolles A.	Microorganisms	10.3390/microorganisms8050723	2020
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Metabolism	Structure and evolution of the bifidobacterial carbohydrate metabolism proteins and enzymes.	Fushinobu S, Abou Hachem M.	Biochem Soc Trans	10.1042/bst20200163	2021
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Genetics	Viability and Composition Validation of Commercial Probiotic Products by Selective Culturing Combined with Next-Generation Sequencing.	Ullah M, Raza A, Ye L, Yu Z.	Microorganisms	10.3390/microorganisms7070188	2019
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Genetics	The estrobolome: Estrogen-metabolizing pathways of the gut microbiome and their relation to breast cancer.	Larnder AH, Manges AR, Murphy RA.	Int J Cancer	10.1002/ijc.35427	2025
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Genetics	Genomic diversity and distribution of Bifidobacterium longum subsp. longum across the human lifespan.	Odamaki T, Bottacini F, Kato K, Mitsuyama E, Yoshida K, Horigome A, Xiao JZ, van Sinderen D.	Sci Rep	10.1038/s41598-017-18391-x	2018
	Species- and Age/Generation-Dependent Adherence of Bifidobacterium bifidum to Human Intestinal Mucus In Vitro.	Harata G, Yoda K, Wang R, Miyazawa K, Sato M, He F, Endo A.	Microorganisms	10.3390/microorganisms9030542	2021
	RNA-Based Anti-Inflammatory Effects of Membrane Vesicles Derived from Lactiplantibacillus plantarum.	Yamasaki-Yashiki S, Kawashima F, Saika A, Hosomi R, Kunisawa J, Katakura Y.	Foods	10.3390/foods13060967	2024
	Co-administration of the prebiotic 1-kestose and the paraprobiotic Lactiplantibacillus plantarum FM8 in magellanic penguins promotes the activity of intestinal Lactobacillaceae and reduces the plc gene levels encoding Clostridium perfringens toxin.	Fujii T, Kezuka C, Kawaguchi Y, Yamakawa S, Kondo N, Funasaka K, Hirooka Y, Tochio T.	J Vet Med Sci	10.1292/jvms.23-0238	2024
	Enzymatic Adaptation of Bifidobacterium bifidum to Host Glycans, Viewed from Glycoside Hydrolyases and Carbohydrate-Binding Modules.	Katoh T, Ojima MN, Sakanaka M, Ashida H, Gotoh A, Katayama T.	Microorganisms	10.3390/microorganisms8040481	2020
Biotechnology	Discovery and Biotechnological Exploitation of Glycoside-Phosphorylases.	Li A, Benkoulouche M, Ladeveze S, Durand J, Cioci G, Laville E, Potocki-Veronese G.	Int J Mol Sci	10.3390/ijms23063043	2022
	Thermal shift assay to identify ligands for bacterial sensor proteins.	Monteagudo-Cascales E, Cano-Munoz M, Genova R, Cabrera JJ, Matilla MA, Krell T.	FEMS Microbiol Rev	10.1093/femsre/fuaf033	2025
	Acidogenic Potential of Oral Bifidobacterium and Its High Fluoride Tolerance.	Manome A, Abiko Y, Kawashima J, Washio J, Fukumoto S, Takahashi N.	Front Microbiol	10.3389/fmicb.2019.01099	2019
Genetics	Milk glycan metabolism by intestinal bifidobacteria: insights from comparative genomics.	Arzamasov AA, Osterman AL.	Crit Rev Biochem Mol Biol	10.1080/10409238.2023.2182272	2022
	Roles of the Cell Surface Architecture of Bacteroides and Bifidobacterium in the Gut Colonization.	Nishiyama K, Yokoi T, Sugiyama M, Osawa R, Mukai T, Okada N.	Front Microbiol	10.3389/fmicb.2021.754819	2021
Metabolism	Characterization of fructooligosaccharide metabolism and fructooligosaccharide-degrading enzymes in human commensal butyrate producers.	Tanno H, Fujii T, Hirano K, Maeno S, Tonozuka T, Sakamoto M, Ohkuma M, Tochio T, Endo A.	Gut Microbes	10.1080/19490976.2020.1869503	2021
	Molecular Insights Into O-Linked Glycan Utilization by Gut Microbes.	Gonzalez-Morelo KJ, Vega-Sagardia M, Garrido D.	Front Microbiol	10.3389/fmicb.2020.591568	2020
Genetics	Comparative Analyses of the Transport Proteins Encoded within the Genomes of nine Bifidobacterium Species.	Zafar H, Saier MH.	Microb Physiol	10.1159/000518954	2022
	A completeness-independent method for pre-selection of closely related genomes for species delineation in prokaryotes.	Zhou Y, Zheng J, Wu Y, Zhang W, Jin J.	BMC Genomics	10.1186/s12864-020-6597-x	2020
	Short-Chain Fatty Acids and Human Health: From Metabolic Pathways to Current Therapeutic Implications.	Facchin S, Bertin L, Bonazzi E, Lorenzon G, De Barba C, Barberio B, Zingone F, Maniero D, Scarpa M, Ruffolo C, Angriman I, Savarino EV.	Life (Basel)	10.3390/life14050559	2024
	Comparative Genomics Revealed Genetic Diversity and Species/Strain-Level Differences in Carbohydrate Metabolism of Three Probiotic Bifidobacterial Species.	Odamaki T, Horigome A, Sugahara H, Hashikura N, Minami J, Xiao JZ, Abe F.	Int J Genomics	10.1155/2015/567809	2015
	Phylogenetic identification of bacterial MazF toxin protein motifs among probiotic strains and foodborne pathogens and potential implications of engineered probiotic intervention in food.	Yan X, Gurtler JB, Fratamico PM, Hu J, Juneja VK.	Cell Biosci	10.1186/2045-3701-2-39	2012
	Utilization of Host-Derived Glycans by Intestinal Lactobacillus and Bifidobacterium Species.	Zuniga M, Monedero V, Yebra MJ.	Front Microbiol	10.3389/fmicb.2018.01917	2018
	Evolutionary switches between two serine codon sets are driven by selection.	Rogozin IB, Belinky F, Pavlenko V, Shabalina SA, Kristensen DM, Koonin EV.	Proc Natl Acad Sci U S A	10.1073/pnas.1615832113	2016
Genetics	Reconstruction of Bacterial and Viral Genomes from Multiple Metagenomes.	Gupta A, Kumar S, Prasoodanan VP, Harish K, Sharma AK, Sharma VK.	Front Microbiol	10.3389/fmicb.2016.00469	2016
Pathogenicity	Manipulation of the diet-microbiota-brain axis in Alzheimer's disease.	Lee D, Lee VM, Hur SK.	Front Neurosci	10.3389/fnins.2022.1042865	2022
Phylogeny	Intraspecies Genomic Diversity and Long-Term Persistence of Bifidobacterium longum.	Chaplin AV, Efimov BA, Smeianov VV, Kafarskaia LI, Pikina AP, Shkoporov AN.	PLoS One	10.1371/journal.pone.0135658	2015
Proteome	Proteinaceous Molecules Mediating Bifidobacterium-Host Interactions.	Ruiz L, Delgado S, Ruas-Madiedo P, Margolles A, Sanchez B.	Front Microbiol	10.3389/fmicb.2016.01193	2016
Metabolism	Broad conservation of milk utilization genes in Bifidobacterium longum subsp. infantis as revealed by comparative genomic hybridization.	LoCascio RG, Desai P, Sela DA, Weimer B, Mills DA.	Appl Environ Microbiol	10.1128/aem.00675-10	2010
Metabolism	Glucuronides in the gut: Sugar-driven symbioses between microbe and host.	Pellock SJ, Redinbo MR.	J Biol Chem	10.1074/jbc.r116.767434	2017
	Intestinal Bacteria as Powerful Trapping Lifeforms for the Elimination of Radioactive Cesium.	Saito K, Kuroda K, Suzuki R, Kino Y, Sekine T, Shinoda H, Yamashiro H, Fukuda T, Kobayashi J, Abe Y, Nishimura J, Urushihara Y, Yoneyama H, Fukumoto M, Isogai E.	Front Vet Sci	10.3389/fvets.2019.00070	2019
Metabolism	The first crystal structure of a family 129 glycoside hydrolase from a probiotic bacterium reveals critical residues and metal cofactors.	Sato M, Liebschner D, Yamada Y, Matsugaki N, Arakawa T, Wills SS, Hattie M, Stubbs KA, Ito T, Senda T, Ashida H, Fushinobu S.	J Biol Chem	10.1074/jbc.m117.777391	2017
Metabolism	Mechanistic investigation of the endo-alpha-N-acetylgalactosaminidase from Streptococcus pneumoniae R6.	Willis LM, Zhang R, Reid A, Withers SG, Wakarchuk WW.	Biochemistry	10.1021/bi9013825	2009
Phylogeny	Age-related changes in gut microbiota composition from newborn to centenarian: a cross-sectional study.	Odamaki T, Kato K, Sugahara H, Hashikura N, Takahashi S, Xiao JZ, Abe F, Osawa R.	BMC Microbiol	10.1186/s12866-016-0708-5	2016
Enzymology	Identification of difructose dianhydride I synthase/hydrolase from an oral bacterium establishes a novel glycoside hydrolase family.	Kashima T, Okumura K, Ishiwata A, Kaieda M, Terada T, Arakawa T, Yamada C, Shimizu K, Tanaka K, Kitaoka M, Ito Y, Fujita K, Fushinobu S.	J Biol Chem	10.1016/j.jbc.2021.101324	2021
Metabolism	The Short-Chain Fatty Acid Acetate in Body Weight Control and Insulin Sensitivity.	Hernandez MAG, Canfora EE, Jocken JWE, Blaak EE.	Nutrients	10.3390/nu11081943	2019
	Characterization of the groEL and groES loci in Bifidobacterium breve UCC 2003: genetic, transcriptional, and phylogenetic analyses.	Ventura M, Canchaya C, Zink R, Fitzgerald GF, van Sinderen D.	Appl Environ Microbiol	10.1128/aem.70.10.6197-6209.2004	2004
	Microbiota and epigenetics: promising therapeutic approaches?	El-Sayed A, Aleya L, Kamel M.	Environ Sci Pollut Res Int	10.1007/s11356-021-15623-6	2021
Metabolism	An ATP Binding Cassette Transporter Mediates the Uptake of alpha-(1,6)-Linked Dietary Oligosaccharides in Bifidobacterium and Correlates with Competitive Growth on These Substrates.	Ejby M, Fredslund F, Andersen JM, Vujicic Zagar A, Henriksen JR, Andersen TL, Svensson B, Slotboom DJ, Abou Hachem M.	J Biol Chem	10.1074/jbc.m116.746529	2016
Genetics	The Gastrointestinal Microbiome: A Review.	Barko PC, McMichael MA, Swanson KS, Williams DA.	J Vet Intern Med	10.1111/jvim.14875	2018
Phylogeny	Phylogenetic framework and molecular signatures for the main clades of the phylum Actinobacteria.	Gao B, Gupta RS.	Microbiol Mol Biol Rev	10.1128/mmbr.05011-11	2012
Genetics	Comparative genomics of the Bifidobacterium breve taxon.	Bottacini F, O'Connell Motherway M, Kuczynski J, O'Connell KJ, Serafini F, Duranti S, Milani C, Turroni F, Lugli GA, Zomer A, Zhurina D, Riedel C, Ventura M, van Sinderen D.	BMC Genomics	10.1186/1471-2164-15-170	2014
Metabolism	Characterization of three beta-galactoside phosphorylases from Clostridium phytofermentans: discovery of d-galactosyl-beta1->4-l-rhamnose phosphorylase.	Nakajima M, Nishimoto M, Kitaoka M.	J Biol Chem	10.1074/jbc.m109.007666	2009
Metabolism	alpha-N-acetylgalactosaminidase from infant-associated bifidobacteria belonging to novel glycoside hydrolase family 129 is implicated in alternative mucin degradation pathway.	Kiyohara M, Nakatomi T, Kurihara S, Fushinobu S, Suzuki H, Tanaka T, Shoda SI, Kitaoka M, Katayama T, Yamamoto K, Ashida H.	J Biol Chem	10.1074/jbc.m111.277384	2012
Metabolism	Cross-feeding by Bifidobacterium breve UCC2003 during co-cultivation with Bifidobacterium bifidum PRL2010 in a mucin-based medium.	Egan M, Motherway MO, Kilcoyne M, Kane M, Joshi L, Ventura M, van Sinderen D.	BMC Microbiol	10.1186/s12866-014-0282-7	2014
Biotechnology	Microbial characterization of probiotics--advisory report of the Working Group "8651 Probiotics" of the Belgian Superior Health Council (SHC).	Huys G, Botteldoorn N, Delvigne F, De Vuyst L, Heyndrickx M, Pot B, Dubois JJ, Daube G.	Mol Nutr Food Res	10.1002/mnfr.201300065	2013
Metabolism	Short fractions of oligofructose are preferentially metabolized by Bifidobacterium animalis DN-173 010.	Van der Meulen R, Avonts L, De Vuyst L.	Appl Environ Microbiol	10.1128/aem.70.4.1923-1930.2004	2004
Metabolism	The Reciprocal Interactions between Polyphenols and Gut Microbiota and Effects on Bioaccessibility.	Ozdal T, Sela DA, Xiao J, Boyacioglu D, Chen F, Capanoglu E.	Nutrients	10.3390/nu8020078	2016
Biotechnology	Lactic acid production - producing microorganisms and substrates sources-state of art.	Abedi E, Hashemi SMB.	Heliyon	10.1016/j.heliyon.2020.e04974	2020
	Comparative analysis of prebiotic effects of four oligosaccharides using in vitro gut model: digestibility, microbiome, and metabolome changes.	Cheon S, Kim G, Bae JH, Lee DH, Seong H, Kim DH, Han JS, Lim SY, Han NS.	FEMS Microbiol Ecol	10.1093/femsec/fiad002	2023
	The novel immunobiotic Clostridium butyricum S-45-5 displays broad-spectrum antiviral activity in vitro and in vivo by inducing immune modulation.	Chathuranga K, Shin Y, Uddin MB, Paek J, Chathuranga WAG, Seong Y, Bai L, Kim H, Shin JH, Chang YH, Lee JS.	Front Immunol	10.3389/fimmu.2023.1242183	2023
	Deciphering the anti-obesity mechanisms of pharmabiotic probiotics through advanced multiomics analysis.	Kim YR, Choi TR, Jo SH, Song WS, Kim T, Kim MG, Baek JH, Kwon SY, Choi BG, Seo SW, Jang CS, Yang YH, Kim YG.	iScience	10.1016/j.isci.2025.111890	2025
	Succession of the microbial community during the process of mechanical and biological pretreatment coupled with a bio-filter for removal of VOCs derived from domestic waste: a field study.	Hou J, Yu C, Meng F, He X, Wang Y, Chen W, Li M.	RSC Adv	10.1039/d1ra05962a	2021
	Technology and potential applications of probiotic encapsulation in fermented milk products.	Iravani S, Korbekandi H, Mirmohammadi SV.	J Food Sci Technol	10.1007/s13197-014-1516-2	2015
	Reviewing the potential of probiotics, prebiotics and synbiotics: advancements in treatment of ulcerative colitis.	Jadhav A, Jagtap S, Vyavahare S, Sharbidre A, Kunchiraman B.	Front Cell Infect Microbiol	10.3389/fcimb.2023.1268041	2023
	Nutritional composition, heavy metal content and in vitro effect on the human gut microbiota of Talitrus saltator, an underutilized crustacean from the Atlantic coast.	Lopez-Santamarina A, Cardelle-Cobas A, Lamas A, Mondragon-Portocarrero A, Cepeda A, Miranda JM.	Front Nutr	10.3389/fnut.2022.943133	2022
	Probiotics, prebiotics and synbiotics: Safe options for next-generation therapeutics.	Yadav MK, Kumari I, Singh B, Sharma KK, Tiwari SK.	Appl Microbiol Biotechnol	10.1007/s00253-021-11646-8	2022
	Bifidobacterium longum CECT 7347 modulates immune responses in a gliadin-induced enteropathy animal model.	Laparra JM, Olivares M, Gallina O, Sanz Y.	PLoS One	10.1371/journal.pone.0030744	2012
Phylogeny	Imbalances in faecal and duodenal Bifidobacterium species composition in active and non-active coeliac disease.	Collado MC, Donat E, Ribes-Koninckx C, Calabuig M, Sanz Y.	BMC Microbiol	10.1186/1471-2180-8-232	2008
	Feasibility of Using Seaweed (Gracilaria coronopifolia) Synbiotic as a Bioactive Material for Intestinal Health.	Li PH, Lu WC, Chan YJ, Zhao YP, Nie XB, Jiang CX, Ji YX.	Foods	10.3390/foods8120623	2019
	Designing primers and evaluation of the efficiency of propidium monoazide - Quantitative polymerase chain reaction for counting the viable cells of Lactobacillus gasseri and Lactobacillus salivarius.	Lai CH, Wu SR, Pang JC, Ramireddy L, Chiang YC, Lin CK, Tsen HY.	J Food Drug Anal	10.1016/j.jfda.2016.10.004	2017
Metabolism	Two alpha-L-arabinofuranosidases from Bifidobacterium longum subsp. longum are involved in arabinoxylan utilization.	Komeno M, Yoshihara Y, Kawasaki J, Nabeshima W, Maeda K, Sasaki Y, Fujita K, Ashida H	Appl Microbiol Biotechnol	10.1007/s00253-022-11845-x	2022
Pathogenicity	Crystal structures of glycoside hydrolase family 136 lacto-N-biosidases from monkey gut- and human adult gut bacteria.	Yamada C, Katayama T, Fushinobu S	Biosci Biotechnol Biochem	10.1093/bbb/zbac015	2022
	Effect of Rosemary (Rosmarinus officinalis L.) Supplementation on Probiotic Yoghurt: Physicochemical Properties, Microbial Content, and Sensory Attributes.	Ali HI, Dey M, Alzubaidi AK, Alneamah SJA, Altemimi AB, Pratap-Singh A	Foods	10.3390/foods10102393	2021
Metabolism	Novel 3-O-alpha-d-Galactosyl-alpha-l-Arabinofuranosidase for the Assimilation of Gum Arabic Arabinogalactan Protein in Bifidobacterium longum subsp. longum.	Sasaki Y, Horigome A, Odamaki T, Xiao JZ, Ishiwata A, Ito Y, Kitahara K, Fujita K	Appl Environ Microbiol	10.1128/AEM.02690-20	2021
Enzymology	Crystal structure of beta-L-arabinobiosidase belonging to glycoside hydrolase family 121.	Saito K, Viborg AH, Sakamoto S, Arakawa T, Yamada C, Fujita K, Fushinobu S	PLoS One	10.1371/journal.pone.0231513	2020
	Properties of recombinant 4-alpha-glucanotransferase from Bifidobacterium longum subsp. longum JCM 1217 and its application.	Jeong DW, Jeong HM, Shin YJ, Woo SH, Shim JH	Food Sci Biotechnol	10.1007/s10068-019-00707-4	2019
Pathogenicity	Rheological properties of a neutral polysaccharide extracted from maca (Lepidium meyenii Walp.) roots with prebiotic and anti-inflammatory activities.	Lee YK, Jung SK, Chang YH	Int J Biol Macromol	10.1016/j.ijbiomac.2020.02.307	2020
Biotechnology	Viability assessment of Bifidobacterium longum ATCC 15707 on non-dairy foods using quantitative fluorescence microscopy.	Min M, Mason SL, Bennett GN, Hussain MA, Bunt CR	J Microbiol Methods	10.1016/j.mimet.2019.105778	2019
Metabolism	Efficient Phytase Secretion and Phytate Degradation by Recombinant Bifidobacterium longum JCM 1217.	Sun Z, Yue Z, Yang X, Hao X, Song M, Li L, Chen C, Chu C, Li C	Front Microbiol	10.3389/fmicb.2019.00796	2019
Metabolism	Two Novel alpha-l-Arabinofuranosidases from Bifidobacterium longum subsp. longum Belonging to Glycoside Hydrolase Family 43 Cooperatively Degrade Arabinan.	Komeno M, Hayamizu H, Fujita K, Ashida H	Appl Environ Microbiol	10.1128/AEM.02582-18	2019
Metabolism	Degradative enzymes for type II arabinogalactan side chains in Bifidobacterium longum subsp. longum.	Fujita K, Sakamoto A, Kaneko S, Kotake T, Tsumuraya Y, Kitahara K	Appl Microbiol Biotechnol	10.1007/s00253-018-9566-4	2018
Metabolism	How accurate is automated gap filling of metabolic models?	Karp PD, Weaver D, Latendresse M	BMC Syst Biol	10.1186/s12918-018-0593-7	2018
Enzymology	Expression and Characterization of Recombinant Sucrose Phosphorylase.	Zhang H, Sun X, Li W, Li T, Li S, Kitaoka M	Protein J	10.1007/s10930-017-9754-6	2018
	Effect of Non-Dairy Food Matrices on the Survival of Probiotic Bacteria during Storage.	Min M, Bunt CR, Mason SL, Bennett GN, Hussain MA	Microorganisms	10.3390/microorganisms5030043	2017
	Beneficial Effect of Bifidobacterium longum ATCC 15707 on Survival Rate of Clostridium difficile Infection in Mice.	Yun B, Song M, Park DJ, Oh S	Korean J Food Sci Anim Resour	10.5851/kosfa.2017.37.3.368	2017
	Effect of a probiotic beverage consumption (Enterococcus faecium CRL 183 and Bifidobacterium longum ATCC 15707) in rats with chemically induced colitis.	Celiberto LS, Bedani R, Dejani NN, Ivo de Medeiros A, Sampaio Zuanon JA, Spolidorio LC, Tallarico Adorno MA, Amancio Varesche MB, Carrilho Galvao F, Valentini SR, Font de Valdez G, Rossi EA, Cavallini DCU	PLoS One	10.1371/journal.pone.0175935	2017
Enzymology	Characterization of novel thermophilic alpha-glucosidase from Bifidobacterium longum.	Kim NR, Jeong DW, Ko DS, Shim JH	Int J Biol Macromol	10.1016/j.ijbiomac.2017.03.009	2017
	Survival of Bifidobacterium longum LMG 13197 microencapsulated in Vegetal or Vegetal-inulin matrix in simulated gastrointestinal fluids and yoghurt.	Amakiri AC, Thantsha MS	Springerplus	10.1186/s40064-016-3010-y	2016
Pathogenicity	Membrane filter method to study the effects of Lactobacillus acidophilus and Bifidobacterium longum on fecal microbiota.	Shimizu H, Benno Y	Microbiol Immunol	10.1111/1348-0421.12332	2015
	Lyophilised Vegetal BM 297 ATO-Inulin lipid-based synbiotic microparticles containing Bifidobacterium longum LMG 13197: design and characterisation.	Amakiri AC, Kalombo L, Thantsha MS	J Microencapsul	10.3109/02652048.2015.1094534	2015
Stress	Cocktails of probiotics pre-adapted to multiple stress factors are more robust under simulated gastrointestinal conditions than their parental counterparts and exhibit enhanced antagonistic capabilities against Escherichia coli and Staphylococcus aureus.	Mathipa MG, Thantsha MS	Gut Pathog	10.1186/s13099-015-0053-5	2015
Enzymology	Bifidobacterium longum subsp. longum Exo-beta-1,3-Galactanase, an enzyme for the degradation of type II arabinogalactan.	Fujita K, Sakaguchi T, Sakamoto A, Shimokawa M, Kitahara K	Appl Environ Microbiol	10.1128/AEM.00802-14	2014
Enzymology	Crystallization and preliminary X-ray diffraction analysis of a novel beta-L-arabinofuranosidase (HypBA1) from Bifidobacterium longum.	Zhu Z, He M, Huang CH, Ko TP, Zeng YF, Huang YN, Jia S, Lu F, Liu JR, Guo RT	Acta Crystallogr F Struct Biol Commun	10.1107/S2053230X14001812	2014
Metabolism	Insights into the binding specificity and catalytic mechanism of N-acetylhexosamine 1-phosphate kinases through multiple reaction complexes.	Wang KC, Lyu SY, Liu YC, Chang CY, Wu CJ, Li TL	Acta Crystallogr D Biol Crystallogr	10.1107/S1399004714004209	2014
Metabolism	Characterization of a novel beta-L-arabinofuranosidase in Bifidobacterium longum: functional elucidation of a DUF1680 protein family member.	Fujita K, Takashi Y, Obuchi E, Kitahara K, Suganuma T	J Biol Chem	10.1074/jbc.M113.528711	2014
Metabolism	Synergistic antibacterial efficacies of the combination of bovine lactoferrin or its hydrolysate with probiotic secretion in curbing the growth of meticillin-resistant Staphylococcus aureus.	Chen PW, Jheng TT, Shyu CL, Mao FC	J Med Microbiol	10.1099/jmm.0.052639-0	2013
Metabolism	Lacto-N-biosidase encoded by a novel gene of Bifidobacterium longum subspecies longum shows unique substrate specificity and requires a designated chaperone for its active expression.	Sakurama H, Kiyohara M, Wada J, Honda Y, Yamaguchi M, Fukiya S, Yokota A, Ashida H, Kumagai H, Kitaoka M, Yamamoto K, Katayama T	J Biol Chem	10.1074/jbc.M113.484733	2013
Metabolism	Antimicrobial potential for the combination of bovine lactoferrin or its hydrolysate with lactoferrin-resistant probiotics against foodborne pathogens.	Chen PW, Jheng TT, Shyu CL, Mao FC	J Dairy Sci	10.3168/jds.2012-6112	2013
	Effects of Enteric-coated Lactoferrin Tablets Containing Lactobacillus brevis subsp. coagulans on Fecal Properties, Defecation Frequency and Intestinal Microbiota of Japanese Women with a Tendency for Constipation: a Randomized Placebo-controlled Crossover Study.	Suzuki N, Murakoshi M, Ono T, Morishita S, Koide M, Bae MJ, Totsuka M, Shimizu M, Sugiyama K, Nishino H, Iida N	Biosci Microbiota Food Health	10.12938/bmfh.32.13	2013
Pathogenicity	Bifidobacterium spp. influences the production of autoinducer-2 and biofilm formation by Escherichia coli O157:H7.	Kim Y, Lee JW, Kang SG, Oh S, Griffiths MW	Anaerobe	10.1016/j.anaerobe.2012.08.006	2012
Enzymology	Characterization of a novel beta-L-Arabinofuranosidase in Bifidobacterium longum: functional elucidation of A DUF1680 family member.	Fujita K, Takashi Y, Obuchi E, Kitahara K, Suganuma T	J Biol Chem	10.1074/jbc.M111.248690	2011
Metabolism	Physiology of consumption of human milk oligosaccharides by infant gut-associated bifidobacteria.	Asakuma S, Hatakeyama E, Urashima T, Yoshida E, Katayama T, Yamamoto K, Kumagai H, Ashida H, Hirose J, Kitaoka M	J Biol Chem	10.1074/jbc.M111.248138	2011
Enzymology	Molecular cloning and characterization of a beta-L-Arabinobiosidase in Bifidobacterium longum that belongs to a novel glycoside hydrolase family.	Fujita K, Sakamoto S, Ono Y, Wakao M, Suda Y, Kitahara K, Suganuma T	J Biol Chem	10.1074/jbc.M110.190512	2010
Pathogenicity	Pivotal Advance: Bifidobacteria and Gram-negative bacteria differentially influence immune responses in the proinflammatory milieu of celiac disease.	De Palma G, Cinova J, Stepankova R, Tuckova L, Sanz Y	J Leukoc Biol	10.1189/jlb.0709471	2009
Metabolism	Development of silk fibroin-based beads for immobilized cell fermentations.	Yildirim S, Borer ME, Wenk E, Meinel L, Lacroix C	J Microencapsul	10.3109/02652040802217516	2010
Pathogenicity	The screening method of a bifidogenic dietary fiber extracted from inedible parts of vegetables.	Iwata E, Hotta H, Goto M	J Nutr Sci Vitaminol (Tokyo)	10.3177/jnsv.55.385	2009
Metabolism	In vitro fermentation of arabinoxylan-derived carbohydrates by bifidobacteria and mixed fecal microbiota.	Pastell H, Westermann P, Meyer AS, Tuomainen P, Tenkanen M	J Agric Food Chem	10.1021/jf901397b	2009
Metabolism	Crystallographic and mutational analyses of substrate recognition of endo-alpha-N-acetylgalactosaminidase from Bifidobacterium longum.	Suzuki R, Katayama T, Kitaoka M, Kumagai H, Wakagi T, Shoun H, Ashida H, Yamamoto K, Fushinobu S	J Biochem	10.1093/jb/mvp086	2009
Pathogenicity	Analysis of tetracycline resistance tet(W) genes and their flanking sequences in intestinal Bifidobacterium species.	Ammor MS, Florez AB, Alvarez-Martin P, Margolles A, Mayo B	J Antimicrob Chemother	10.1093/jac/dkn280	2008
Pathogenicity	Differential transcriptional response of Bifidobacterium longum to human milk, formula milk, and galactooligosaccharide.	Gonzalez R, Klaassens ES, Malinen E, de Vos WM, Vaughan EE	Appl Environ Microbiol	10.1128/AEM.00122-08	2008
Enzymology	Identification of galacto-N-biose phosphorylase from Clostridium perfringens ATCC13124.	Nakajima M, Nihira T, Nishimoto M, Kitaoka M	Appl Microbiol Biotechnol	10.1007/s00253-007-1319-8	2008
Enzymology	Purification, crystallization and preliminary X-ray analysis of the galacto-N-biose-/lacto-N-biose I-binding protein (GL-BP) of the ABC transporter from Bifidobacterium longum JCM1217.	Wada J, Suzuki R, Fushinobu S, Kitaoka M, Wakagi T, Shoun H, Ashida H, Kumagai H, Katayama T, Yamamoto K	Acta Crystallogr Sect F Struct Biol Cryst Commun	10.1107/S1744309107036263	2007
Metabolism	Identification of N-acetylhexosamine 1-kinase in the complete lacto-N-biose I/galacto-N-biose metabolic pathway in Bifidobacterium longum.	Nishimoto M, Kitaoka M	Appl Environ Microbiol	10.1128/AEM.01425-07	2007
Enzymology	Identification and molecular cloning of a novel glycoside hydrolase family of core 1 type O-glycan-specific endo-alpha-N-acetylgalactosaminidase from Bifidobacterium longum.	Fujita K, Oura F, Nagamine N, Katayama T, Hiratake J, Sakata K, Kumagai H, Yamamoto K	J Biol Chem	10.1074/jbc.M506874200	2005
Metabolism	Novel putative galactose operon involving lacto-N-biose phosphorylase in Bifidobacterium longum.	Kitaoka M, Tian J, Nishimoto M	Appl Environ Microbiol	10.1128/AEM.71.6.3158-3162.2005	2005
Metabolism	Optimization of a Bifidobacterium longum production process.	Kiviharju K, Leisola M, Eerikainen T	J Biotechnol	10.1016/j.jbiotec.2005.02.007	2005
Metabolism	Kinetics of Bifidobacterium longum ATCC 15707 fermentations: effect of the dilution rate and carbon source.	Shene C, Mardones M, Zamora P, Bravo S	Appl Microbiol Biotechnol	10.1007/s00253-004-1792-2	2005
Metabolism	Fermentation of a milk-soymilk and Lycium chinense Miller mixture using a new isolate of Lactobacillus paracasei subsp. paracasei NTU101 and Bifidobacterium longum.	Lin FM, Chiu CH, Pan TM	J Ind Microbiol Biotechnol	10.1007/s10295-004-0184-z	2004
Pathogenicity	Increased stress tolerance of Bifidobacterium longum and Lactococcus lactis produced during continuous mixed-strain immobilized-cell fermentation.	Doleyres Y, Fliss I, Lacroix C	J Appl Microbiol	10.1111/j.1365-2672.2004.02326.x	2004
Metabolism	Continuous production of mixed lactic starters containing probiotics using immobilized cell technology.	Doleyres Y, Fliss I, Lacroix C	Biotechnol Prog	10.1021/bp020096w	2004
Metabolism	Bifidobacterium longum ATCC 15707 cell production during free- and immobilized-cell cultures in MRS-whey permeate medium.	Doleyres Y, Paquin C, LeRoy M, Lacroix C	Appl Microbiol Biotechnol	10.1007/s00253-002-1103-8	2002
	Quantitative determination of the spatial distribution of pure- and mixed-strain immobilized cells in gel beads by immunofluorescence.	Doleyres Y, Fliss I, Lacroix C	Appl Microbiol Biotechnol	10.1007/s00253-002-1004-x	2002
Enzymology	Cloning and expression in Escherichia coli of a gene, hup, encoding the histone-like protein HU of Bifidobacterium longum.	Takeuchi A, Matsumura H, Kano Y	Biosci Biotechnol Biochem	10.1271/bbb.66.598	2002
Metabolism	Formulations and processing of yogurt affect the microbial quality of carbonated yogurt.	Karagul-Yuceer Y, Wilson JC, White CH	J Dairy Sci	10.3168/jds.S0022-0302(01)74506-7	2001
Cultivation	Survival of Bifidobacterium longum immobilized in calcium alginate beads in simulated gastric juices and bile salt solution.	Lee KY, Heo TR	Appl Environ Microbiol	10.1128/AEM.66.2.869-873.2000	2000
Metabolism	Investigations of bifidobacterial ecology and oligosaccharide metabolism in a three-stage compound continuous culture system.	McBain AJ, Macfarlane GT	Scand J Gastroenterol Suppl	10.1080/00365521.1997.11720715	1997
Enzymology	Viability and enzymatic activity of bifidobacteria in milk.	Hughes DB, Hoover DG	J Dairy Sci	10.3168/jds.S0022-0302(95)76634-6	1995
Genetics	Selection of species-specific DNA probes which detect strain restriction polymorphism in four Bifidobacterium species.	Mangin I, Bourget N, Simonet JM, Decaris B	Res Microbiol	10.1016/0923-2508(96)80271-3	1995
Cultivation	Effect of chelatants on gellan gel rheological properties and setting temperature for immobilization of living bifidobacteria.	Camelin I, Lacroix C, Paquin C, Prevost H, Cachon R, Divies C	Biotechnol Prog	10.1021/bp00021a008	1993
Pathogenicity	Quantitative fluorometric assay for rapid enzymatic characterization of Bifidobacterium longum and related bifidobacteria.	O'Brien M, Mitsuoka T	Microbiol Immunol	10.1111/j.1348-0421.1991.tb01626.x	1991
	Preparation of the bifidus milk powder.	Nagawa M, Nakabayashi A, Fujino S	J Dairy Sci	10.3168/jds.S0022-0302(88)79745-3	1988
	In vivo Trial of Bifidobacterium longum Revealed the Complex Network Correlations Between Gut Microbiota and Health Promotional Effects.	Kim YT, Kim CH, Kwon JG, Cho JH, Shin YS, Kim HB, Lee JH	Front Microbiol	10.3389/fmicb.2022.886934	2022
Phylogeny	Proposal to reclassify the three biotypes of Bifidobacterium longum as three subspecies: Bifidobacterium longum subsp. longum subsp. nov., Bifidobacterium longum subsp. infantis comb. nov. and Bifidobacterium longum subsp. suis comb. nov.	Mattarelli P, Bonaparte C, Pot B, Biavati B	Int J Syst Evol Microbiol	10.1099/ijs.0.65319-0	2008

References

#8612	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 20219
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#38030	; Curators of the CIP;
#49449	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 28903
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68371	Automatically annotated from API 50CH acid .
#68382	Automatically annotated from API zym .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#120652	Collection of Institut Pasteur ; Curators of the CIP; CIP 64.62
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Bifidobacterium longum subsp. longum (DSM 20219, ATCC 15707, NCTC 11818)

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