Name: Burkholderia mallei NCTC 12938
Creator: BacDive
License: https://creativecommons.org/licenses/by/4.0/

Strain identifier

BacDive ID: 169112

Type strain:

Species: Burkholderia mallei

Culture col. no.: NCTC 12938, ATCC 23344

NCBI tax ID(s): 243160 (strain), 13373 (species)

SI-ID 87678

ATCC 23344, NCTC 12938

Section

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Burkholderia mallei NCTC 12938 is a bacterium of the family Burkholderiaceae.

16S sequence
Bacteria
genome sequence

Information on the name and the taxonomic classification. Name and taxonomic classification

	Last LPSN update	09-12-2024 (DD-MM-YYYY)
	Domain	*Bacteria*
	Phylum	*Pseudomonadota*
	Class	*Betaproteobacteria*
	Order	*Burkholderiales*
	Family	*Burkholderiaceae*
	Genus	*Burkholderia*
	Species	**Burkholderia mallei**
	Full Scientific Name (LPSN)	Burkholderia mallei (Zopf 1885) Yabuuchi et al. 1993

	Synonym	Pseudomonas mallei
	Synonym	"Bacillus* mallei"*
	Synonym	"Malleomyces* mallei"*

Information on morphological and physiological properties Morphology

[Ref.: #125439]	Gram stain	negative Confidence in %94.3
[Ref.: #125438]	Gram stain	negative Confidence in %98.5

Information on physiology and metabolism Physiology and metabolism

[Ref.: #125439]

Oxygen tolerance

obligate aerobe Confidence in %98.8

[Ref.: #125439]

Ability of spore formation

no Confidence in %92.8

Information on isolation source, the sampling and environmental conditions Isolation, sampling and environmental information

[Ref.: #69479]

Global distribution of 16S sequence AF110188 (>99% sequence identity) for Burkholderia from Microbeatlas

Aquatic Samples	1640
Soil Samples	4295
Animal Samples	7137
Plant Samples	2419
Total Samples	15491

Information on possible application of the strain and its possible interaction with e.g. potential hosts Safety information

[Ref.: #20215]

Biosafety level

Risk group

Information on genomic background e.g. entries in nucleic sequence databass Sequence information

16S Sequence information:

	Sequence accession description	Seq. accession number	Sequence length (bp)	Sequence database	Associated NCBI tax ID
[Ref.: #20215]	Burkholderia mallei strain ATCC 23344 16S ribosomal RNA gene, complete sequence	AF110188	1488	GenBank ENA	13373 tax ID
[Ref.: #124043]	Burkholderia mallei gene for 16S rRNA, partial sequence, strain: ATCC 23344 (= EY 2233, = RH 627, = NCTC 7383).	D13057	160	GenBank ENA	13373 tax ID	*

Genome sequence information:

	Sequence accession description	Seq. accession number	Assembly level	Sequence database	Associated NCBI tax ID
[Ref.: #66792]	Burkholderia mallei ATCC 23344	GCA_000011705	complete	GenBank ENA	243160 tax ID	*
[Ref.: #66792]	Burkholderia mallei NCTC12938	GCA_900446245	contig	GenBank ENA	13373 tax ID	*
[Ref.: #66792]	Burkholderia mallei ATCC 23344	243160.12	complete	PATRIC	243160 tax ID	*
[Ref.: #66792]	Burkholderia mallei strain NCTC12938	13373.76	wgs	PATRIC	13373 tax ID	*

Data predicted using genome information as a basis Genome-based predictions

	Model	Trait	Prediction	Confidence in %	In training data
	Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Burkholderia mallei ATCC 23344 ATCC 23344 NCBI: GCA_000011705.1
[Ref.: #125438]	gram-positive	gram-positiveⓘ	no	98.5	no
[Ref.: #125438]	anaerobic	anaerobicⓘ	no	96.93	no
[Ref.: #125438]	aerobic	aerobicⓘ	yes	88.287	no
[Ref.: #125438]	spore-forming	spore-formingⓘ	no	88.572	no
[Ref.: #125438]	thermophile	thermophilicⓘ	no	98	no
[Ref.: #125438]	motile2+	flagellatedⓘ	yes	83.568	no

	Model	Trait	Prediction	Confidence in %
	Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Burkholderia mallei ATCC 23344 NCBI: GCA_000011705
[Ref.: #125439]	BacteriaNet	spore_formationⓘ	no	92.8
[Ref.: #125439]	BacteriaNet	motilityⓘ	yes	68.3
[Ref.: #125439]	BacteriaNet	gram_stainⓘ	negative	94.3
[Ref.: #125439]	BacteriaNet	oxygen_toleranceⓘ	obligate aerobe	98.8

Availability in culture collections External links

[Ref.: #20215]

Culture collection no.

NCTC 12938, ATCC 23344

[Ref.: #115381]

SI-ID 87678

Literature:

Only first 10 entries are displayed. Click here to see all.

Topic	Title	Authors	Journal	DOI	Year
Pathogenicity	Validation of a Lateral Flow Test for the Presumptive Identification of the Presence of Burkholderia mallei or Burkholderia pseudomallei in Environmental Samples.	Venkateswaran KS, Parameswaran N, Sarwar J, Plummer A, Santos A, Pillai CA, Bowen S, Granville M, Selvan S, Babu P, Thirunavukkarasu N, Venkateswaran N, Sharma S, Morse SA, Anderson K, Hodge DR, Pillai SP	Health Secur	10.1089/hs.2021.0168	2022	*
Metabolism	DBSecSys 2.0: a database of Burkholderia mallei and Burkholderia pseudomallei secretion systems.	Memisevic V, Kumar K, Zavaljevski N, DeShazer D, Wallqvist A, Reifman J	BMC Bioinformatics	10.1186/s12859-016-1242-z	2016	*
Pathogenicity	Mining host-pathogen protein interactions to characterize Burkholderia mallei infectivity mechanisms.	Memisevic V, Zavaljevski N, Rajagopala SV, Kwon K, Pieper R, DeShazer D, Reifman J, Wallqvist A	PLoS Comput Biol	10.1371/journal.pcbi.1004088	2015	*
Pathogenicity	Oropharyngeal aspiration of Burkholderia mallei and Burkholderia pseudomallei in BALB/c mice.	Schully KL, Bell MG, Ward JM, Keane-Myers AM	PLoS One	10.1371/journal.pone.0115066	2014	*
Metabolism	Characterization of an autotransporter adhesin protein shared by Burkholderia mallei and Burkholderia pseudomallei.	Lafontaine ER, Balder R, Michel F, Hogan RJ	BMC Microbiol	10.1186/1471-2180-14-92	2014	*
Pathogenicity	Use of a safe, reproducible, and rapid aerosol delivery method to study infection by Burkholderia pseudomallei and Burkholderia mallei in mice.	Lafontaine ER, Zimmerman SM, Shaffer TL, Michel F, Gao X, Hogan RJ	PLoS One	10.1371/journal.pone.0076804	2013	*
Pathogenicity	Alanine racemase mutants of Burkholderia pseudomallei and Burkholderia mallei and use of alanine racemase as a non-antibiotic-based selectable marker.	Zajdowicz SL, Jones-Carson J, Vazquez-Torres A, Jobling MG, Gill RE, Holmes RK	PLoS One	10.1371/journal.pone.0021523	2011	*
Metabolism	Burkholderia thailandensis oacA mutants facilitate the expression of Burkholderia mallei-like O polysaccharides.	Brett PJ, Burtnick MN, Heiss C, Azadi P, DeShazer D, Woods DE, Gherardini FC	Infect Immun	10.1128/IAI.01023-10	2010	*
Phylogeny	Identification of Burkholderia mallei and Burkholderia pseudomallei adhesins for human respiratory epithelial cells.	Balder R, Lipski S, Lazarus JJ, Grose W, Wooten RM, Hogan RJ, Woods DE, Lafontaine ER	BMC Microbiol	10.1186/1471-2180-10-250	2010	*
Genetics	ATP-binding cassette systems in Burkholderia pseudomallei and Burkholderia mallei.	Harland DN, Dassa E, Titball RW, Brown KA, Atkins HS	BMC Genomics	10.1186/1471-2164-8-83	2007	*
Enzymology	Development of a polymerase chain reaction assay for the specific identification of Burkholderia mallei and differentiation from Burkholderia pseudomallei and other closely related Burkholderiaceae.	Ulrich RL, Ulrich MP, Schell MA, Kim HS, DeShazer D	Diagn Microbiol Infect Dis	10.1016/j.diagmicrobio.2005.11.007	2006	*
Phylogeny	Genome-wide identification and mapping of variable sequences in the genomes of Burkholderia mallei and Burkholderia pseudomallei.	Fushan A, Monastyrskaya G, Abaev I, Kostina M, Filyukova O, Pecherskih E, Sverdlov E	Res Microbiol	10.1016/j.resmic.2004.09.009	2004	*
Genetics	Structural flexibility in the Burkholderia mallei genome.	Nierman WC, DeShazer D, Kim HS, Tettelin H, Nelson KE, Feldblyum T, Ulrich RL, Ronning CM, Brinkac LM, Daugherty SC, Davidsen TD, Deboy RT, Dimitrov G, Dodson RJ, Durkin AS, Gwinn ML, Haft DH, Khouri H, Kolonay JF, Madupu R, Mohammoud Y, Nelson WC, Radune D, Romero CM, Sarria S, Selengut J, Shamblin C, Sullivan SA, White O, Yu Y, Zafar N, Zhou L, Fraser CM	Proc Natl Acad Sci U S A	10.1073/pnas.0403306101	2004	*
Genetics	Burkholderia thailandensis E125 harbors a temperate bacteriophage specific for Burkholderia mallei.	Woods DE, Jeddeloh JA, Fritz DL, DeShazer D	J Bacteriol	10.1128/JB.184.14.4003-4017.2002	2002	*
Genetics	Identification of a Burkholderia mallei polysaccharide gene cluster by subtractive hybridization and demonstration that the encoded capsule is an essential virulence determinant.	DeShazer D, Waag DM, Fritz DL, Woods DE	Microb Pathog	10.1006/mpat.2000.0430	2001	*
Pathogenicity	Evaluation of Burkholderia mallei DeltatonB Deltahcp1 (CLH001) as a live attenuated vaccine in murine models of glanders and melioidosis.	Khakhum N, Bharaj P, Myers JN, Tapia D, Walker DH, Endsley JJ, Torres AG	PLoS Negl Trop Dis	10.1371/journal.pntd.0007578	2019	*
Metabolism	Phenotypic Characterization of a Novel Virulence-Factor Deletion Strain of Burkholderia mallei That Provides Partial Protection against Inhalational Glanders in Mice.	Bozue JA, Chaudhury S, Amemiya K, Chua J, Cote CK, Toothman RG, Dankmeyer JL, Klimko CP, Wilhelmsen CL, Raymond JW, Zavaljevski N, Reifman J, Wallqvist A	Front Cell Infect Microbiol	10.3389/fcimb.2016.00021	2016	*
Metabolism	The Autotransporter BpaB Contributes to the Virulence of Burkholderia mallei in an Aerosol Model of Infection.	Zimmerman SM, Michel F, Hogan RJ, Lafontaine ER	PLoS One	10.1371/journal.pone.0126437	2015	*
Pathogenicity	Use of the common marmoset to study Burkholderia mallei infection.	Jelesijevic T, Zimmerman SM, Harvey SB, Mead DG, Shaffer TL, Estes DM, Michel F, Quinn FD, Hogan RJ, Lafontaine ER	PLoS One	10.1371/journal.pone.0124181	2015	*
Metabolism	DBSecSys: a database of Burkholderia mallei secretion systems.	Memisevic V, Kumar K, Cheng L, Zavaljevski N, DeShazer D, Wallqvist A, Reifman J	BMC Bioinformatics	10.1186/1471-2105-15-244	2014	*
Pathogenicity	Novel Burkholderia mallei virulence factors linked to specific host-pathogen protein interactions.	Memisevic V, Zavaljevski N, Pieper R, Rajagopala SV, Kwon K, Townsend K, Yu C, Yu X, DeShazer D, Reifman J, Wallqvist A	Mol Cell Proteomics	10.1074/mcp.M113.029041	2013	*
Pathogenicity	Comparison of the in vitro and in vivo susceptibilities of Burkholderia mallei to Ceftazidime and Levofloxacin.	Judy BM, Whitlock GC, Torres AG, Estes DM	BMC Microbiol	10.1186/1471-2180-9-88	2009	*
Metabolism	A disruption of ctpA encoding carboxy-terminal protease attenuates Burkholderia mallei and induces partial protection in CD1 mice.	Bandara AB, DeShazer D, Inzana TJ, Sriranganathan N, Schurig GG, Boyle SM	Microb Pathog	10.1016/j.micpath.2008.05.005	2008	*
Genetics	The factors shaping synonymous codon usage in the genome of Burkholderia mallei.	Zhao S, Zhang Q, Chen Z, Zhao Y, Zhong J	J Genet Genomics	10.1016/S1673-8527(07)60039-3	2007	*
Metabolism	Octanoyl-homoserine lactone is the cognate signal for Burkholderia mallei BmaR1-BmaI1 quorum sensing.	Duerkop BA, Ulrich RL, Greenberg EP	J Bacteriol	10.1128/JB.00317-07	2007	*
Enzymology	mini-Tn7 insertion in bacteria with multiple glmS-linked attTn7 sites: example Burkholderia mallei ATCC 23344.	Choi KH, DeShazer D, Schweizer HP	Nat Protoc	10.1038/nprot.2006.25	2006	*
Genetics	Genome sequence alterations detected upon passage of Burkholderia mallei ATCC 23344 in culture and in mammalian hosts.	Romero CM, DeShazer D, Feldblyum T, Ravel J, Woods D, Kim HS, Yu Y, Ronning CM, Nierman WC	BMC Genomics	10.1186/1471-2164-7-228	2006	*
Metabolism	The animal pathogen-like type III secretion system is required for the intracellular survival of Burkholderia mallei within J774.2 macrophages.	Ribot WJ, Ulrich RL	Infect Immun	10.1128/IAI.01939-05	2006	*
Enzymology	Detection of the reemerging agent Burkholderia mallei in a recent outbreak of glanders in the United Arab Emirates by a newly developed fliP-based polymerase chain reaction assay.	Scholz HC, Joseph M, Tomaso H, Al Dahouk S, Witte A, Kinne J, Hagen RM, Wernery R, Wernery U, Neubauer H	Diagn Microbiol Infect Dis	10.1016/j.diagmicrobio.2005.09.018	2006	*
Metabolism	Quorum sensing: a transcriptional regulatory system involved in the pathogenicity of Burkholderia mallei.	Ulrich RL, Deshazer D, Hines HB, Jeddeloh JA	Infect Immun	10.1128/IAI.72.11.6589-6596.2004	2004	*
Phylogeny	Genome-wide comparison reveals great inter- and intraspecies variability in B. pseudomallei and B. mallei pathogens.	Monastyrskaya G, Fushan A, Abaev I, Filyukova O, Kostina M, Pecherskih E, Sverdlov E	Res Microbiol	10.1016/j.resmic.2004.05.014	2004	*
Metabolism	Type III secretion: a virulence factor delivery system essential for the pathogenicity of Burkholderia mallei.	Ulrich RL, DeShazer D	Infect Immun	10.1128/IAI.72.2.1150-1154.2004	2004	*
Metabolism	Experimental aerogenic Burkholderia mallei (glanders) infection in the BALB/c mouse.	Lever MS, Nelson M, Ireland PI, Stagg AJ, Beedham RJ, Hall GA, Knight G, Titball RW	J Med Microbiol	10.1099/jmm.0.05180-0	2003	*
	Antibodies against In Vivo-Expressed Antigens Are Sufficient To Protect against Lethal Aerosol Infection with Burkholderia mallei and Burkholderia pseudomallei.	Zimmerman SM, Dyke JS, Jelesijevic TP, Michel F, Lafontaine ER, Hogan RJ	Infect Immun	10.1128/IAI.00102-17	2017	*
	Autotransporters and Their Role in the Virulence of Burkholderia pseudomallei and Burkholderia mallei.	Lazar Adler NR, Stevens JM, Stevens MP, Galyov EE	Front Microbiol	10.3389/fmicb.2011.00151	2011	*
	The Peptidoglycan-associated lipoprotein Pal contributes to the virulence of Burkholderia mallei and provides protection against lethal aerosol challenge.	Dyke JS, Huertas-Diaz MC, Michel F, Holladay NE, Hogan RJ, He B, Lafontaine ER	Virulence	10.1080/21505594.2020.1804275	2020	*
	Virulence of Burkholderia mallei quorum-sensing mutants.	Majerczyk C, Kinman L, Han T, Bunt R, Greenberg EP	Infect Immun	10.1128/IAI.00048-13	2013	*
	Protective antigens against glanders identified by expression library immunization.	Whitlock GC, Robida MD, Judy BM, Qazi O, Brown KA, Deeraksa A, Taylor K, Massey S, Loskutov A, Borovkov AY, Brown K, Cano JA, Torres AG, Estes DM, Sykes KF	Front Microbiol	10.3389/fmicb.2011.00227	2011	*
	Protective response to subunit vaccination against intranasal Burkholderia mallei and B. pseudomallei challenge.	Whitlock GC, Deeraksa A, Qazi O, Judy BM, Taylor K, Propst KL, Duffy AJ, Johnson K, Kitto GB, Brown KA, Dow SW, Torres AG, Estes DM	Procedia Vaccinol	10.1016/j.provac.2010.03.013	2010	*
	Aerogenic vaccination with a Burkholderia mallei auxotroph protects against aerosol-initiated glanders in mice.	Ulrich RL, Amemiya K, Waag DM, Roy CJ, DeShazer D	Vaccine	10.1016/j.vaccine.2004.10.017	2005	*
	Molecular and physical characterization of Burkholderia mallei O antigens.	Burtnick MN, Brett PJ, Woods DE	J Bacteriol	10.1128/JB.184.3.849-852.2002	2002	*

References

#20215

Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )

#66792

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#69479

João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .

#115381

Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.: StrainInfo: A central database for resolving microbial strain identifiers . ( DOI 10.60712/SI-ID87678.1 )

#124043

Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .

#125438

Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )

#125439

Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .

* These data were automatically processed and therefore are not curated

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Burkholderia mallei ATCC 23344 ATCC 23344

Burkholderia mallei ATCC 23344

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