Megasphaera vaginalis (BV3C16-1, ATCC TSD- 207, DSM 111203)

Name: Megasphaera vaginalis (BV3C16-1, ATCC TSD- 207, DSM 111203)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 166921

Type strain

Strain Designation BV3C16-1, Type3

Culture col. no. BV3C16-1 ATCC TSD- 207 DSM 111203 Type3

NCBI tax ID(s) 1111454

Special Collections DSMZ

History DSMZ <- D. Fredricks, Fred Hutchinson Cancer Research Center; BV3C16-1

Links

Megasphaera vaginalis BV3C16-1 is a bacterium that was isolated from human vagiinal fluid.

genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 283197

DSM 111203

@ref 20215

Last LPSN update 2026-05-29 08:46:01

Domain Bacteria

Phylum Bacillota

Class Negativicutes

Order Veillonellales

Family Veillonellaceae

Genus Megasphaera

Species Megasphaera vaginalis

Full scientific name Megasphaera vaginalis Srinivasan et al. 2021

Morphology

Culture and growth conditions

Culture medium

@ref	Name	Growth	Medium link	Composition
125258	COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)		Medium recipe at MediaDive	Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base
125258	CHOPPED MEAT MEDIUM WITH CARBOHYDRATES (DSMZ Medium 110)		Medium recipe at MediaDive	Name: CHOPPED MEAT MEDIUM WITH CARBOHYDRATES (DSMZ Medium 110) Composition: Ground beef 500.0 g/l Casitone 30.0 g/l Agar 15.0 g/l K2HPO4 5.0 g/l Yeast extract 5.0 g/l D-Glucose 4.0 g/l Maltose 1.0 g/l Cellobiose 1.0 g/l Starch 1.0 g/l L-Cysteine HCl 0.5 g/l Ethanol 0.19 g/l Haemin 0.005 g/l Vitamin K3 0.0005 g/l Sodium resazurin 0.0005 g/l Distilled water Water Vitamin K1 NaOH

Culture temp

@ref	Growth	Type	Temperature (°C)
125258	positive	growth	37

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
125439	facultative anaerobe	94.103

Isolation, sampling and environmental information

Isolation

@ref	Sample type	Host species	Geographic location	Country	Country ISO 3 Code	Continent	Latitude	Longitude
125258	human vagiinal fluid	Homo sapiens	Seattle, WA	USA	USA	North America	47.606	-122.332 47.606/-122.332

Taxonmaps

69479

Global distribution of 16S sequence JN809775 (>99% sequence identity) for Megasphaera from Microbeatlas

Aquatic Samples	229
Soil Samples	96
Animal Samples	9247
Plant Samples	21
Total Samples	9593

Interaction and safety

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	MspBV3C16-1v1.0 assembly for Megasphaera vaginalis (ex Srinivasan et al. 2021) BV3C16-1	contig	GCA_000478965	1111454.3	2558860389	1111454	65.61

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
20215	Megasphaera sp. BV3C16-1 16S ribosomal RNA gene, partial sequence	JN809775	1452		1111454

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: MspBV3C16-1v1.0 assembly for Megasphaera vaginalis (ex Srinivasan et al. 2021) BV3C16-1
NCBI: GCA_000478965

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	motility	BacteriaNetⓘ	yes	44.46	no
125439	gram_stain	BacteriaNetⓘ	positive	52.98	no
125439	oxygen_tolerance	BacteriaNetⓘ	facultative anaerobe	94.10	no
125439	spore_formation	BacteriaNetⓘ	yes	44.01	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Megasphaera vaginalis BV3C16-1
NCBI: GCA_000478965.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	no	88.63	no
125438	anaerobic	anaerobicⓘ	yes	87.77	no
125438	aerobic	aerobicⓘ	no	94.25	no
125438	spore-forming	spore-formingⓘ	no	76.50	no
125438	thermophilic	thermophileⓘ	no	92.39	no
125438	flagellated	motile2+ⓘ	no	85.62	no

Literature

Topic	Title	Authors	Journal	DOI	Year
Phylogeny	Megasphaera lornae sp. nov., Megasphaera hutchinsoni sp. nov., and Megasphaera vaginalis sp. nov.: novel bacteria isolated from the female genital tract.	Srinivasan S, Beamer MA, Fiedler TL, Austin MN, Sizova MV, Strenk SM, Agnew KJ, Gowda GAN, Raftery D, Epstein SS, Fredricks DN, Hillier SL	Int J Syst Evol Microbiol	10.1099/ijsem.0.004702	2021

References

#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#125258	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 111203
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Megasphaera vaginalis (BV3C16-1, ATCC TSD- 207, DSM 111203)

Name and taxonomic classification

Morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Isolation, sampling and environmental information

Isolation

Taxonmaps

Interaction and safety

Sequence information

Genome sequences

Genome browser: GCA_000478965

16S sequences

Genome-based predictions

Predictions

Literature

Literature

References

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