Cutibacterium acnes subsp. acnes JCM 6495 is a bacterium that produces polysaccharides.
polysaccharide production genome sequence 16S sequence Bacteria| @ref 20215 |
Last LPSN update
2026-02-09 11:40:05 |
| Domain Bacteria |
| Phylum Actinomycetota |
| Class Actinomycetes |
| Order Propionibacteriales |
| Family Propionibacteriaceae |
| Genus Cutibacterium |
| Species Cutibacterium acnes subsp. acnes |
| Full scientific name Cutibacterium acnes subsp. acnes (Gilchrist 1900) Nouioui et al. 2018 |
| Synonyms (2) |
Global distribution of 16S sequence AB693168 (>99% sequence identity) for Cutibacterium acnes from Microbeatlas 
 Aquatic Samples |
7473 |
 Soil Samples |
3573 |
 Animal Samples |
47966 |
 Plant Samples |
1257 |
| Total Samples | 60269 |
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|
| 67770 | ASM886832v1 assembly for Cutibacterium acnes ATCC 11827 | contig | GCA_008868325   | 1747.867  | 1747 | 70.44 |
| @ref | Description | Accession | Length | Database | NCBI tax ID | |
|---|---|---|---|---|---|---|
| 67770 | Propionibacterium acnes gene for 16S ribosomal RNA, partial sequence, strain: JCM 6495 | AB693168 | 1486 | | 1747 |
| @ref | GC-content (mol%) | Method | |
|---|---|---|---|
| 67770 | 57 | thermal denaturation, midpoint method (Tm) |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Phylogeny | Classification of Cutibacterium acnes at phylotype level by MALDI-MS proteotyping. | Teramoto K, Okubo T, Yamada Y, Sekiya S, Iwamoto S, Tanaka K. | Proc Jpn Acad Ser B Phys Biol Sci | 10.2183/pjab.95.042 | 2019 |  |
| Synthesis, in vitro and in silico evaluation of halogenated xanthone and benzophenone derivatives as antibacterial agents against acne-causing bacteria. | Devakrishnan P, Nasir NM, Hasan H, Tejo BA, Baharuddin FF. | Bioorg Chem | 10.1016/j.bioorg.2025.108906 | 2025 | | |
| Integrated Machine Learning and Structure-Based Virtual Screening Identifies Natural Product Targeting 50S Ribosome Inhibitory Activity Against Cutibacterium acnes. | Liu J, Tong HHY, Zheng H, Lei MIF, Li S. | Molecules | 10.3390/molecules30224433 | 2025 | | |
| Reversal Potential of Multidrug Antibiotic Resistance in Cutibacterium acnes by Ethanol Extracts of Rhubarb. | Yang D, Cui Y, Zhu S, Wang R, Xu H, Zhao G, Zhang D, Liang Y. | Microbiologyopen | 10.1002/mbo3.70096 | 2025 | | |
| Pathogenicity | A Mixture of Water-Soluble Polysaccharides Reduces Caspase-1 and IL-1beta Inflammatory Responses by Cutibacterium acnes in vitro in Reconstructed Human Epidermis (RHE). | Gruber JV, Terpak N, Massard S, Chen X, Kim Y. | Clin Cosmet Investig Dermatol | 10.2147/ccid.s487881 | 2024 | |
| Minocycline Nanocrystals: A New Approach for Treating Acne with Reduced Systemic Side Effects. | Abudoleh SM, Abu Ershaid JM, Lafi D, Dahshan NA, Talhouni A, Abuirmeileh A. | Pharmaceutics | 10.3390/pharmaceutics17060727 | 2025 | | |
| Formulation and Characterization of PLGA Minocycline Microneedles for Enhanced Skin Deposition and Antibacterial Activity in Acne Treatment. | Abu Ershaid JM, Abudoleh SM, Lafi DN, Dahshan NA. | Polymers (Basel) | 10.3390/polym17212912 | 2025 | | |
| The antibacterial activity of berberine against Cutibacterium acnes: its therapeutic potential in inflammatory acne. | Sun L, Yu Q, Peng F, Sun C, Wang D, Pu L, Xiong F, Tian Y, Peng C, Zhou Q. | Front Microbiol | 10.3389/fmicb.2023.1276383 | 2023 | | |
| Assessment of the Anti-Acne Properties of Some Medicinal Plants and Development of an Herbal Anti-Acne Formulation. | Deniz FSS, Oyardi O, Bozkurt Guzel C, Yalcin TE, Yigitkan S, Kan Y, Ulger Toprak N, Orhan IE. | Pharmaceutics | 10.3390/pharmaceutics17030317 | 2025 | | |
| Phytochemicals, promising strategies combating Cutibacterium acnes. | Sun C, Na Y, Wang Z, Zhu T, Liu X. | Front Pharmacol | 10.3389/fphar.2024.1476670 | 2024 | | |
| Effect of Different Arnica montana L. Plant Parts on the Essential Oil Composition, Antimicrobial Activity, and Synergistic Interactions with Antibiotics. | Sugier P, Sugier D, Miazga-Karska M, Nurzynska A, Krol B, Seczyk L, Kowalski R. | Molecules | 10.3390/molecules30183812 | 2025 | | |
| Synovial Fluid Cutibacterium acnes Antigen Is Detected Among Shoulder Samples with High Inflammation and Early Culture Growth. | Toler KO, Paranjape PR, McLaren A, Deirmengian C. | J Bone Joint Surg Am | 10.2106/jbjs.23.00409 | 2024 | | |
| Genomic and Phenotypic Characterization of Cutibacterium acnes Bacteriophages Isolated from Acne Patients. | Kim S, Song H, Jin JS, Lee WJ, Kim J. | Antibiotics (Basel) | 10.3390/antibiotics11081041 | 2022 | | |
| In vitro evaluation of microbial D- and L-lactate production as biomarkers of infection. | Morovic P, Gonzalez Moreno M, Trampuz A, Karbysheva S. | Front Microbiol | 10.3389/fmicb.2024.1406350 | 2024 | | |
| Essential Oil Compounds in Combination with Conventional Antibiotics for Dermatology. | Simbu S, Orchard A, Vuuren SV. | Molecules | 10.3390/molecules29061225 | 2024 | | |
| Nasturtium officinale Microshoot Culture Multiplied in PlantForm Bioreactor-Phytochemical Profiling and Biological Activity. | Klimek-Szczykutowicz M, Malinowska MA, Galka A, Blazevic I, Dulovic A, Paprocka P, Wrzosek M, Szopa A. | Molecules | 10.3390/molecules30040936 | 2025 | | |
| Antimicrobial Activity of Stilbenes from Bletilla striata against Cutibacterium acnes and Its Effect on Cell Membrane. | Yu Q, Sun L, Peng F, Sun C, Xiong F, Sun M, Liu J, Peng C, Zhou Q. | Microorganisms | 10.3390/microorganisms11122958 | 2023 | | |
| Vancomycin is effective in preventing Cutibacterium acnes growth in a mimetic shoulder arthroplasty. | Miquel J, Huang TB, Athwal GS, Faber KJ, O'Gorman DB. | J Shoulder Elbow Surg | 10.1016/j.jse.2021.06.015 | 2022 | | |
| Hop Extract: An Efficacious Antimicrobial and Anti-biofilm Agent Against Multidrug-Resistant Staphylococci Strains and Cutibacterium acnes. | Di Lodovico S, Menghini L, Ferrante C, Recchia E, Castro-Amorim J, Gameiro P, Cellini L, Bessa LJ. | Front Microbiol | 10.3389/fmicb.2020.01852 | 2020 | | |
| Investigating the Effect of Enzymatically-Derived Blackcurrant Extract on Skin Staphylococci Using an In Vitro Human Stratum Corneum Model. | Corovic M, Petrov Ivankovic A, Milivojevic A, Pfeffer K, Homey B, Jansen PAM, Zeeuwen PLJM, van den Bogaard EH, Bezbradica D. | Pharmaceutics | 10.3390/pharmaceutics17040487 | 2025 | | |
| Skin dysbiosis and Cutibacterium acnes biofilm in inflammatory acne lesions of adolescents. | Cavallo I, Sivori F, Truglio M, De Maio F, Lucantoni F, Cardinali G, Pontone M, Bernardi T, Sanguinetti M, Capitanio B, Cristaudo A, Ascenzioni F, Morrone A, Pimpinelli F, Di Domenico EG. | Sci Rep | 10.1038/s41598-022-25436-3 | 2022 | | |
| A pilot study on the efficacy of topical lotion containing anti-acne postbiotic in subjects with mild -to -moderate acne. | Cui H, Guo C, Wang Q, Feng C, Duan Z. | Front Med (Lausanne) | 10.3389/fmed.2022.1064460 | 2022 | | |
| Exploring the Antimicrobial Properties of 99 Natural Flavour and Fragrance Raw Materials against Pathogenic Bacteria: A Comparative Study with Antibiotics. | Bacinska Z, Baberowska K, Surowiak AK, Balcerzak L, Strub DJ. | Plants (Basel) | 10.3390/plants12213777 | 2023 | | |
| In Vitro Antibacterial and Anti-Inflammatory Activity of Arctostaphylos uva-ursi Leaf Extract against Cutibacterium acnes. | Dell'Annunziata F, Cometa S, Della Marca R, Busto F, Folliero V, Franci G, Galdiero M, De Giglio E, De Filippis A. | Pharmaceutics | 10.3390/pharmaceutics14091952 | 2022 | | |
| Pathogenicity | Biological Efficacy Evaluation of a Non-Cross-Linked Hyaluronic Acid Dermal Filler for Biomedical Application in Inflammatory Scalp Conditions. | Sommatis S, Capillo MC, Liga E, Maccario C, Rauso R, Herrera M, Zerbinati N, Mocchi R. | Life (Basel) | 10.3390/life12010002 | 2021 | |
| Development of Novel Topical Anti-Acne Cream Containing Postbiotics for Mild-to-Moderate Acne: An Observational Study to Evaluate Its Efficacy. | Cui H, Feng C, Guo C, Duan Z. | Indian J Dermatol | 10.4103/ijd.ijd_655_22 | 2022 | | |
| Pathogenicity | Effect of Tranexamic Acid against Staphylococcus spp. and Cutibacterium acnes Associated with Peri-Implant Infection: Results from an In Vitro Study. | Benjumea A, Diaz-Navarro M, Hafian R, Sanchez-Somolinos M, Vaquero J, Chana F, Munoz P, Guembe M. | Microbiol Spectr | 10.1128/spectrum.01612-21 | 2022 | |
| Pathogenicity | Effect of commonly used cosmetic preservatives on skin resident microflora dynamics. | Pinto D, Ciardiello T, Franzoni M, Pasini F, Giuliani G, Rinaldi F. | Sci Rep | 10.1038/s41598-021-88072-3 | 2021 | |
| Enzymology | Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays. | Mussi L, Baby AR, Camargo Junior FB, Padovani G, Sufi BDS, Magalhaes WV. | Molecules | 10.3390/molecules26216704 | 2021 | |
| Efficacy of Two Moroccan Cistus Species Extracts against Acne Vulgaris: Phytochemical Profile, Antioxidant, Anti-Inflammatory and Antimicrobial Activities. | Bouabidi M, Salamone FL, Gadhi C, Bouamama H, Speciale A, Ginestra G, Pulvirenti L, Siracusa L, Nostro A, Cristani M. | Molecules | 10.3390/molecules28062797 | 2023 | | |
| Bioactivities of Karanda (Carissa carandas Linn.) fruit extracts for novel cosmeceutical applications. | Khuanekkaphan M, Khobjai W, Noysang C, Wisidsri N, Thungmungmee S. | J Adv Pharm Technol Res | 10.4103/japtr.japtr_254_20 | 2021 | | |
| Staphylococcus epidermidis and Cutibacterium acnes: Two Major Sentinels of Skin Microbiota and the Influence of Cosmetics. | Fourniere M, Latire T, Souak D, Feuilloley MGJ, Bedoux G. | Microorganisms | 10.3390/microorganisms8111752 | 2020 | | |
| Phytochemical Profile and Biological Activity of the Ethanolic Extract from the Aerial Part of Crocus alatavicus Regel & Semen Growing Wildly in Southern Kazakhstan. | Allambergenova Z, Kasela M, Adamczuk G, Humeniuk E, Iwan M, Swiatek L, Boguszewska A, Rajtar B, Jozefczyk A, Baj T, Wojtanowski KK, Korulkin D, Kozhanova K, Ibragimova L, Sakipova Z, Tyskiewicz K, Malm A, Skalicka-Wozniak K. | Molecules | 10.3390/molecules27113468 | 2022 | | |
| Pathogenicity | Biophysical and Biological Tools to Better Characterize the Stability, Safety and Efficacy of a Cosmeceutical for Acne-Prone Skin. | Sommatis S, Capillo MC, Maccario C, Liga E, Grimaldi G, Rauso R, Bencini PL, Guida S, Zerbinati N, Mocchi R. | Molecules | 10.3390/molecules27041255 | 2022 | |
| Microbiological Control of Cellular Products: The Relevance of the Cellular Matrix, Incubation Temperature, and Atmosphere for the Detection Performance of Automated Culture Systems. | Gunther SK, Geiss C, Kaiser SJ, Mutters NT, Gunther F. | Transfus Med Hemother | 10.1159/000503397 | 2020 | | |
| pH-Dependent Antibacterial Activity of Glycolic Acid: Implications for Anti-Acne Formulations. | Valle-Gonzalez ER, Jackman JA, Yoon BK, Mokrzecka N, Cho NJ. | Sci Rep | 10.1038/s41598-020-64545-9 | 2020 | | |
| Pathogenicity | Is Implant Coating With Tyrosol- and Antibiotic-loaded Hydrogel Effective in Reducing Cutibacterium (Propionibacterium) acnes Biofilm Formation? A Preliminary In Vitro Study. | Tsikopoulos K, Bidossi A, Drago L, Petrenyov DR, Givissis P, Mavridis D, Papaioannidou P. | Clin Orthop Relat Res | 10.1097/corr.0000000000000663 | 2019 | |
| Evaluation of the Antimicrobial and Antivirulent Potential of Essential Oils Isolated from Juniperus oxycedrus L. ssp. macrocarpa Aerial Parts. | Spengler G, Gajdacs M, Donadu MG, Usai M, Marchetti M, Ferrari M, Mazzarello V, Zanetti S, Nagy F, Kovacs R. | Microorganisms | 10.3390/microorganisms10040758 | 2022 | | |
| Experimental procedures for decontamination and microbiological testing in cardiovascular tissue banks. | Suss PH, Ribeiro VST, Cieslinski J, Kraft L, Tuon FF. | Exp Biol Med (Maywood) | 10.1177/1535370218820515 | 2018 | | |
| Simulating transmission of ESKAPE pathogens plus C. difficile in relevant clinical scenarios. | Weber KL, LeSassier DS, Kappell AD, Schulte KQ, Westfall N, Albright NC, Godbold GD, Palsikar V, Acevedo CA, Ternus KL, Hewitt FC. | BMC Infect Dis | 10.1186/s12879-020-05121-4 | 2020 | | |
| Biotechnology | Sweet Basil (Ocimum basilicum L.)-A Review of Its Botany, Phytochemistry, Pharmacological Activities, and Biotechnological Development. | Azizah NS, Irawan B, Kusmoro J, Safriansyah W, Farabi K, Oktavia D, Doni F, Miranti M. | Plants (Basel) | 10.3390/plants12244148 | 2023 | |
| Genetics | Clinical and Biological Features of Cutibacterium (Formerly Propionibacterium) avidum, an Underrecognized Microorganism. | Corvec S. | Clin Microbiol Rev | 10.1128/cmr.00064-17 | 2018 | |
| An In Vitro Study of the Anti-Acne Effects of Scutellaria barbata. | Zheng Q, Jin X, Nguyen TTM, Park SJ, Yi GS, Yang SJ, Yi TH. | Molecules | 10.3390/molecules30030515 | 2025 | | |
| Different Prostatic Tissue Microbiomes between High- and Low-Grade Prostate Cancer Pathogenesis. | Kim JH, Seo H, Kim S, Rahim MA, Jo S, Barman I, Tajdozian H, Sarafraz F, Song HY, Song YS. | Int J Mol Sci | 10.3390/ijms25168943 | 2024 | | |
| Peel-off emulgel mask of Cocos nucifera L. Extract using gelling agent carbomer 940 as antiacne against Propionibacterium acnes ATCC 11827. | Hariyadi DM, Isnaeni I, Sudarma S, Suciati S, Rosita N | J Adv Pharm Technol Res | 10.4103/japtr.JAPTR_51_20 | 2020 | | |
| Pathogenicity | Lactobacillus paraplantarum THG-G10 as a potential anti-acne agent with anti-bacterial and anti-inflammatory activities. | Cha H, Kim SK, Kook M, Yi TH | Anaerobe | 10.1016/j.anaerobe.2020.102243 | 2020 | |
| Radial Extracorporeal Shock Wave Therapy Against Cutibacterium acnes Implant-Associated Infections: An in Vitro Trial. | Tsikopoulos K, Drago L, Koutras G, Givissis P, Vagdatli E, Soukiouroglou P, Papaioannidou P | Microorganisms | 10.3390/microorganisms8050743 | 2020 | | |
| The in vitro antimicrobial evaluation of commercially essential oils and their combinations against acne. | Orchard A, van Vuuren SF, Viljoen AM, Kamatou G | Int J Cosmet Sci | 10.1111/ics.12456 | 2018 | | |
| Genetics | In vitro emergence of fluoroquinolone resistance in Cutibacterium (formerly Propionibacterium) acnes and molecular characterization of mutations in the gyrA gene. | Takoudju EM, Guillouzouic A, Kambarev S, Pecorari F, Corvec S | Anaerobe | 10.1016/j.anaerobe.2017.06.005 | 2017 | |
| Pathogenicity | In vitro antimicrobial activity of benzoyl peroxide against Propionibacterium acnes assessed by a novel susceptibility testing method. | Okamoto K, Ikeda F, Kanayama S, Nakajima A, Matsumoto T, Ishii R, Umehara M, Gotoh N, Hayashi N, Iyoda T, Matsuzaki K, Matsumoto S, Kawashima M | J Infect Chemother | 10.1016/j.jiac.2015.12.010 | 2016 | |
| Pathogenicity | Evaluation of antibacterial and anti-inflammatory activities of less polar ginsenosides produced from polar ginsenosides by heat-transformation. | Wang L, Yang X, Yu X, Yao Y, Ren G | J Agric Food Chem | 10.1021/jf404461q | 2013 | |
| Genetics | In vitro emergence of rifampicin resistance in Propionibacterium acnes and molecular characterization of mutations in the rpoB gene. | Furustrand Tafin U, Trampuz A, Corvec S | J Antimicrob Chemother | 10.1093/jac/dks428 | 2012 | |
| Pathogenicity | Long-chain 3-acyl-4-hydroxycoumarins: structure and antibacterial activity. | Cravotto G, Tagliapietra S, Cappello R, Palmisano G, Curini M, Boccalini M | Arch Pharm (Weinheim) | 10.1002/ardp.200500127 | 2006 | |
| Enzymology | Two-dimensional gel electrophoresis of ribosomal proteins from Propionibacterium acnes and granulosum. | Dekio S, Hashimoto K, Makino M | Zentralbl Bakteriol | 10.1016/s0934-8840(89)80103-3 | 1989 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive165408.20251217.10
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
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