Streptomyces varsoviensis (DSM 40346, ATCC 14631c, ATCC 25505)

Name: Streptomyces varsoviensis (DSM 40346, ATCC 14631c, ATCC 25505)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 16065

Type strain

Strain Designation 13-I

Culture col. no. DSM 40346 ATCC 14631c ATCC 25505 CBS 357.64 CBS 647.69 30 more

NCBI tax ID(s) 67373

Special Collections DSMZ JCM Wink compendium JMRC JMRC

History DSMZ <- E.B. Shirling, ISP <- W. Kurylowicz, 13-1 JCM <-- KCC S-0523 <-- IFO 13093 <-- SAJ <-- ISP 5346 <-- W. Kury?owicz 13-1.

Links

Streptomyces varsoviensis 13-I is a bacterium that produces antibiotic compounds and was isolated from soil.

antibiotic compound production genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 92753

LMG 19360,ATCC 25505,CCRC 12647,DSM 40346,IFO 13093,IMET 43351,JCM 4303,JCM 4523,NCIMB 9522,NRRL B-3589,MTCC 1537,ATCC 14631,NCIB 9522,DSM 40677,VKM Ac-1000,CBS 647.69,CBS 357.64,AS 4.1431,NBRC 13093,BCRC 12647,HAMBI 1046,NCAIM B.01482,CGMCC 4.1431

@ref 20215

Last LPSN update 2026-05-29 08:28:41

Domain Bacteria

Phylum Actinomycetota

Class Actinomycetes

Order Kitasatosporales

Family Streptomycetaceae

Genus Streptomyces

Species Streptomyces varsoviensis

Full scientific name Streptomyces varsoviensis Kurylowicz and Woznicka 1967 (Approved Lists 1980)

BacDive ID	Other strains from **Streptomyces varsoviensis** (3)	Type strain
127864	S. varsoviensis SF001226,
127865	S. varsoviensis SF004159,
178889	S. varsoviensis YIM31659, ST034013

Morphology

Cell morphology

@ref	Gram stain	Confidence
125438	positive	91.555
125439	positive	99.638
125439		95.945

Colony morphology

@ref	Colony color	Medium used
69259	Copper brown (8004)	ISP 5
69259	Brown beige (1011), beige brown (8024)	suter with tyrosine
69259	Brown beige (1011)	ISP 4
69259	Brown beige (1011)	suter without tyrosine
69259	Ochre brown (8001), clay brown (8003)	ISP 2
69259	Olive brown (8008), nut brown (8011)	ISP 6
69259	Sand yellow (1002)	ISP 3
69259	Signal orange (2010)	ISP 7

Multicellular morphology

@ref	Complex name	Medium name
69259	Aerial mycelium	ISP 2
69259	Aerial mycelium	ISP 3
69259	Aerial mycelium	ISP 4
69259	Aerial mycelium	ISP 5
69259	Aerial mycelium	ISP 6
69259	Aerial mycelium	ISP 7
69259	Aerial mycelium	suter with tyrosine
69259	Aerial mycelium	suter without tyrosine

Pigmentation

@ref	Production	Color	Name
69259			melanin pigment
69259		Brown beige (1011), sand yellow (1002), clay brown (8003), ochre brown (8001)	soluble pigment

Multimedia

@ref:	9474
multimedia content:	DSM_40346.jpg
multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_40346.jpg
caption:	Medium 65 28°C
intellectual property rights:	© Leibniz-Institut DSMZ
manual_annotation:	1

@ref:	69259
multimedia content:	DSM_40346_image6.jpeg
multimedia.multimedia content:	DSM_40346_image6.jpeg
caption:	(ISP6, ISP7, SSM+T, SSM-T)
intellectual property rights:	Helmholtz-Zentrum für Infektionsforschung GmbH
manual_annotation:	1

@ref:	69259
multimedia content:	DSM_40346_image8.jpeg
multimedia.multimedia content:	DSM_40346_image8.jpeg
caption:	(ISP6, ISP7, SSM+T, SSM-T)
intellectual property rights:	Helmholtz-Zentrum für Infektionsforschung GmbH
manual_annotation:	1

Culture and growth conditions

Culture medium

@ref	Name	Growth	Medium link	Composition
9474	GYM STREPTOMYCES MEDIUM (DSMZ Medium 65)		Medium recipe at MediaDive	Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 18.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water

Culture temp

@ref	Growth	Type	Temperature (°C)
9474	positive	growth	28
67770	positive	growth	28

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
125439	obligate aerobe	98.705

Spore formation

@ref	Spore formation	Confidence
125439		96.458
125438		91.925

Compound production

@ref	Compound
9474	oxytetracycline
20216	Oxytetracycline

Halophily

@ref	Salt	Growth	Tested relation	Concentration
69259	NaCl	positive	growth	0-7.5 %

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
69259	22599 ChEBI	arabinose	+/-	growth
69259	62968 ChEBI	cellulose	-	growth
68379	17634 ChEBI	D-glucose	-	fermentation	from API Coryne
68379	16899 ChEBI	D-mannitol	-	fermentation	from API Coryne
68379	16988 ChEBI	D-ribose	-	fermentation	from API Coryne
68379	65327 ChEBI	D-xylose	-	fermentation	from API Coryne
68379	4853 ChEBI	esculin	-	hydrolysis	from API Coryne
69259	28757 ChEBI	fructose	+	growth
68379	5291 ChEBI	gelatin	-	hydrolysis	from API Coryne
69259	17234 ChEBI	glucose	+	growth
68379	28087 ChEBI	glycogen	-	fermentation	from API Coryne
68379	17716 ChEBI	lactose	-	fermentation	from API Coryne
68379	17306 ChEBI	maltose	-	fermentation	from API Coryne
69259	37684 ChEBI	mannose	+	growth
69259	17268 ChEBI	myo-inositol	-	growth
68379	17632 ChEBI	nitrate	-	reduction	from API Coryne
69259	16634 ChEBI	raffinose	-	growth
69259	26546 ChEBI	rhamnose	+/-	growth
68379	17992 ChEBI	sucrose	-	fermentation	from API Coryne
69259	17992 ChEBI	sucrose	-	growth
68379	16199 ChEBI	urea	-	hydrolysis	from API Coryne
69259	18222 ChEBI	xylose	-	growth

Metabolite production

@ref	Chebi-ID	Metabolite	Production
67770	27701 ChEBI	oxytetracycline

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
68382	alkaline phosphatase	+	3.1.3.1	from API zym
68379	alkaline phosphatase	+	3.1.3.1	from API Coryne
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68382	alpha-glucosidase	-	3.2.1.20	from API zym
68379	alpha-glucosidase	-	3.2.1.20	from API Coryne
68382	beta-galactosidase	-	3.2.1.23	from API zym
68379	beta-galactosidase	-	3.2.1.23	from API Coryne
68382	beta-glucosidase	-	3.2.1.21	from API zym
68379	beta-glucosidase	-	3.2.1.21	from API Coryne
68382	beta-glucuronidase	-	3.2.1.31	from API zym
68379	beta-glucuronidase	-	3.2.1.31	from API Coryne
68382	cystine arylamidase	-	3.4.11.3	from API zym
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
68379	gelatinase	-		from API Coryne
68382	leucine arylamidase	+	3.4.11.1	from API zym
68382	lipase (C 14)	-		from API zym
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68379	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API Coryne
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
68379	pyrazinamidase	-	3.5.1.B15	from API Coryne
68379	pyrrolidonyl arylamidase	-	3.4.19.3	from API Coryne
68382	trypsin	-	3.4.21.4	from API zym
68379	urease	-	3.5.1.5	from API Coryne

Pathway annotation

Computationally determined by

@ref	pathway	enzyme coverage	annotated reactions
66794	valine metabolism	100	9 of 9
66794	adipate degradation	100	2 of 2
66794	cis-vaccenate biosynthesis	100	2 of 2
66794	4-hydroxymandelate degradation	100	9 of 9
66794	ribulose monophosphate pathway	100	2 of 2
66794	cyanate degradation	100	3 of 3
66794	aspartate and asparagine metabolism	100	9 of 9
66794	enterobactin biosynthesis	100	3 of 3
66794	glycine betaine biosynthesis	100	5 of 5
66794	formaldehyde oxidation	100	3 of 3
66794	phenylacetate degradation (aerobic)	100	5 of 5
66794	ethanol fermentation	100	2 of 2
66794	aminopropanol phosphate biosynthesis	100	2 of 2
66794	butanoate fermentation	100	4 of 4
66794	cardiolipin biosynthesis	100	7 of 7
66794	methylglyoxal degradation	100	5 of 5
66794	biotin biosynthesis	100	4 of 4
66794	kanosamine biosynthesis II	100	2 of 2
66794	pentose phosphate pathway	100	11 of 11
66794	ppGpp biosynthesis	100	4 of 4
66794	hydrogen production	100	5 of 5
66794	threonine metabolism	100	10 of 10
66794	coenzyme A metabolism	100	4 of 4
66794	UDP-GlcNAc biosynthesis	100	3 of 3
66794	ceramide biosynthesis	100	1 of 1
66794	palmitate biosynthesis	100	22 of 22
66794	sulfopterin metabolism	100	4 of 4
66794	anapleurotic synthesis of oxalacetate	100	1 of 1
66794	isoleucine metabolism	100	8 of 8
66794	taurine degradation	100	1 of 1
66794	acetate fermentation	100	4 of 4
66794	aerobactin biosynthesis	100	1 of 1
66794	folate polyglutamylation	100	1 of 1
66794	suberin monomers biosynthesis	100	2 of 2
66794	cellulose degradation	100	5 of 5
66794	CDP-diacylglycerol biosynthesis	100	2 of 2
66794	CO2 fixation in Crenarchaeota	100	9 of 9
66794	tetrahydrofolate metabolism	92.86	13 of 14
66794	heme metabolism	92.86	13 of 14
66794	phenylalanine metabolism	92.31	12 of 13
66794	leucine metabolism	92.31	12 of 13
66794	proline metabolism	90.91	10 of 11
66794	phenol degradation	90	18 of 20
66794	Entner Doudoroff pathway	90	9 of 10
66794	starch degradation	90	9 of 10
66794	myo-inositol biosynthesis	90	9 of 10
66794	tryptophan metabolism	89.47	34 of 38
66794	glutamate and glutamine metabolism	89.29	25 of 28
66794	molybdenum cofactor biosynthesis	88.89	8 of 9
66794	serine metabolism	88.89	8 of 9
66794	chorismate metabolism	88.89	8 of 9
66794	ketogluconate metabolism	87.5	7 of 8
66794	gluconeogenesis	87.5	7 of 8
66794	C4 and CAM-carbon fixation	87.5	7 of 8
66794	dTDPLrhamnose biosynthesis	87.5	7 of 8
66794	alanine metabolism	86.21	25 of 29
66794	reductive acetyl coenzyme A pathway	85.71	6 of 7
66794	ubiquinone biosynthesis	85.71	6 of 7
66794	citric acid cycle	85.71	12 of 14
66794	photosynthesis	85.71	12 of 14
66794	propanol degradation	85.71	6 of 7
66794	vitamin B1 metabolism	84.62	11 of 13
66794	glycolate and glyoxylate degradation	83.33	5 of 6
66794	purine metabolism	82.98	78 of 94
66794	vitamin B12 metabolism	82.35	28 of 34
66794	glycolysis	82.35	14 of 17
66794	3-chlorocatechol degradation	80	4 of 5
66794	flavin biosynthesis	80	12 of 15
66794	gallate degradation	80	4 of 5
66794	peptidoglycan biosynthesis	80	12 of 15
66794	3-phenylpropionate degradation	80	12 of 15
66794	metabolism of amino sugars and derivatives	80	4 of 5
66794	ethylmalonyl-CoA pathway	80	4 of 5
66794	factor 420 biosynthesis	80	4 of 5
66794	4-hydroxyphenylacetate degradation	80	8 of 10
66794	glycogen metabolism	80	4 of 5
66794	propionate fermentation	80	8 of 10
66794	NAD metabolism	77.78	14 of 18
66794	d-mannose degradation	77.78	7 of 9
66794	allantoin degradation	77.78	7 of 9
66794	urea cycle	76.92	10 of 13
66794	pyrimidine metabolism	75.56	34 of 45
66794	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	75	6 of 8
66794	glycogen biosynthesis	75	3 of 4
66794	cyclohexanol degradation	75	3 of 4
66794	arginine metabolism	75	18 of 24
66794	CMP-KDO biosynthesis	75	3 of 4
66794	degradation of aromatic, nitrogen containing compounds	75	9 of 12
66794	metabolism of disaccharids	72.73	8 of 11
66794	oxidative phosphorylation	72.53	66 of 91
66794	histidine metabolism	72.41	21 of 29
66794	degradation of hexoses	72.22	13 of 18
66794	degradation of sugar acids	72	18 of 25
66794	glutathione metabolism	71.43	10 of 14
66794	aclacinomycin biosynthesis	71.43	5 of 7
66794	non-pathway related	71.05	27 of 38
66794	lipid metabolism	70.97	22 of 31
66794	methionine metabolism	69.23	18 of 26
66794	androgen and estrogen metabolism	68.75	11 of 16
66794	degradation of sugar alcohols	68.75	11 of 16
66794	daunorubicin biosynthesis	66.67	6 of 9
66794	(5R)-carbapenem carboxylate biosynthesis	66.67	2 of 3
66794	acetyl CoA biosynthesis	66.67	2 of 3
66794	L-lactaldehyde degradation	66.67	2 of 3
66794	acetoin degradation	66.67	2 of 3
66794	1,4-dihydroxy-6-naphthoate biosynthesis	66.67	4 of 6
66794	octane oxidation	66.67	2 of 3
66794	IAA biosynthesis	66.67	2 of 3
66794	tyrosine metabolism	64.29	9 of 14
66794	cholesterol biosynthesis	63.64	7 of 11
66794	carnitine metabolism	62.5	5 of 8
66794	lysine metabolism	61.9	26 of 42
66794	cysteine metabolism	61.11	11 of 18
66794	glycine metabolism	60	6 of 10
66794	vitamin K metabolism	60	3 of 5
66794	lipoate biosynthesis	60	3 of 5
66794	arachidonate biosynthesis	60	3 of 5
66794	benzoyl-CoA degradation	57.14	4 of 7
66794	sulfate reduction	53.85	7 of 13
66794	phenylpropanoid biosynthesis	53.85	7 of 13
66794	degradation of pentoses	50	14 of 28
66794	coenzyme M biosynthesis	50	5 of 10
66794	lactate fermentation	50	2 of 4
66794	selenocysteine biosynthesis	50	3 of 6
66794	mannosylglycerate biosynthesis	50	1 of 2
66794	chlorophyll metabolism	50	9 of 18
66794	dolichol and dolichyl phosphate biosynthesis	50	1 of 2
66794	toluene degradation	50	2 of 4
66794	isoprenoid biosynthesis	50	13 of 26
66794	pantothenate biosynthesis	50	3 of 6
66794	phenylmercury acetate degradation	50	1 of 2
66794	vitamin E metabolism	50	2 of 4
66794	quinate degradation	50	1 of 2
66794	bile acid biosynthesis, neutral pathway	47.06	8 of 17
66794	vitamin B6 metabolism	45.45	5 of 11
66794	carotenoid biosynthesis	45.45	10 of 22
66794	nitrate assimilation	44.44	4 of 9
66794	lipid A biosynthesis	44.44	4 of 9
66794	polyamine pathway	43.48	10 of 23
66794	ascorbate metabolism	40.91	9 of 22
66794	bacilysin biosynthesis	40	2 of 5
66794	D-cycloserine biosynthesis	40	2 of 5
66794	O-antigen biosynthesis	40	2 of 5
66794	d-xylose degradation	36.36	4 of 11
66794	methanogenesis from CO2	33.33	4 of 12
66794	sphingosine metabolism	33.33	2 of 6
66794	phosphatidylethanolamine bioynthesis	30.77	4 of 13
66794	mevalonate metabolism	28.57	2 of 7
66794	dolichyl-diphosphooligosaccharide biosynthesis	27.27	3 of 11
66794	alginate biosynthesis	25	1 of 4
66794	catecholamine biosynthesis	25	1 of 4
66794	arachidonic acid metabolism	22.22	4 of 18

API coryne

@ref	Reduction of nitrateNIT	PYZ	PYRA	PAL	beta GUR	beta GAL	alpha GLU	beta NAG	ESC	URE	GEL	Control fermentationControl	GLU	RIB	XYL	MAN	MAL	LAC	SAC	GLYG	CAT
69259	-	-	-	+	-	-	-	-	-	-	-	not determinedn.d.	-	-	-	-	-	-	-	-	not determinedn.d.

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
69259	not determinedn.d.	+	+	+	-	+	+/-	-	-	-	+	+	-	-	-	-	-	-	+/-	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Environmental	#Terrestrial	#Soil

Isolation

9474

Sample typesoil

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
9474	1	Risk group (German classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
67770	ASM71863v1 assembly for Streptomyces varsoviensis NRRL ISP-5346	contig	GCA_000718635	67373.4	2765236004	67373	53.4
67770	ASM71925v1 assembly for Streptomyces varsoviensis NRRL B-3589	contig	GCA_000719255	67373.5	2765236014	67373	46.07
67770	ASM127059v1 assembly for Streptomyces varsoviensis NRRL B-3589	contig	GCA_001270595	67373.10	2765236008	67373	0

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Streptomyces varsoviensis gene for 16S ribosomal RNA, partial sequence, strain: JCM 4523	D44211	121	67373
20218	Streptomyces varsoviensis gene for 16S rRNA, partial sequence, strain: NBRC 13093	AB184306	1475	67373
20218	Streptomyces varsoviensis strain NRRL B-3589 16S ribosomal RNA gene, partial sequence	DQ026653	1499	67373

GC content

@ref	GC-content (mol%)	Method
67770	72.4	genome sequence analysis

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: ASM71863v1 assembly for Streptomyces varsoviensis NRRL ISP-5346
NCBI: GCA_000718635

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	obligate aerobe	98.71	no
125439	motility	BacteriaNetⓘ	no	95.95	no
125439	gram_stain	BacteriaNetⓘ	positive	99.64	no
125439	spore_formation	BacteriaNetⓘ	yes	96.46	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Streptomyces varsoviensis NRRL ISP-5346
NCBI: GCA_000718635.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	91.56	no
125438	anaerobic	anaerobicⓘ	no	96.81	no
125438	aerobic	aerobicⓘ	yes	86.32	no
125438	spore-forming	spore-formingⓘ	yes	91.93	no
125438	thermophilic	thermophileⓘ	no	96.00	no
125438	flagellated	motile2+ⓘ	no	87.00	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	Exploration, expansion and definition of the atropopeptide family of ribosomally synthesized and posttranslationally modified peptides.	Biermann F, Tan B, Breitenbach M, Kakumu Y, Nanudorn P, Dimitrova Y, Walker AS, Ueoka R, Helfrich EJN.	Chem Sci	10.1039/d4sc03469d	2024
Metabolism	Uncovering the unexplored diversity of thioamidated ribosomal peptides in Actinobacteria using the RiPPER genome mining tool.	Santos-Aberturas J, Chandra G, Frattaruolo L, Lacret R, Pham TH, Vior NM, Eyles TH, Truman AW.	Nucleic Acids Res	10.1093/nar/gkz192	2019
Genetics	Targeted Large-Scale Genome Mining and Candidate Prioritization for Natural Product Discovery.	Malit JJL, Leung HYC, Qian PY.	Mar Drugs	10.3390/md20060398	2022
	Discovery of Tricyclic Aromatic Polyketides Reveals Hidden Chain-Length Flexibility in Type II Polyketide Synthases	Liu Y, Wang L, Wang H, Zhu Y, Sun J, Ma B, Liu L, Bao X, Ren J, Fan K, Wang L, Li X, Pan G.	Int J Mol Sci		2025
Genetics	Biological characterization of the hygrobafilomycin antibiotic JBIR-100 and bioinformatic insights into the hygrolide family of natural products.	Molloy EM, Tietz JI, Blair PM, Mitchell DA.	Bioorg Med Chem	10.1016/j.bmc.2016.05.021	2016
Metabolism	Prescreening bacterial colonies for bioactive molecules with Janus plates, a SBS standard double-faced microbial culturing system.	Sanchez-Hidalgo M, Pascual J, de la Cruz M, Martin J, Kath GS, Sigmund JM, Masurekar P, Vicente F, Genilloud O, Bills GF.	Antonie Van Leeuwenhoek	10.1007/s10482-012-9746-7	2012
Cultivation	Catechol siderophores framed on 2,3-dihydroxybenzoyl-L-serine from Streptomyces varsoviensis.	Liu Z, Huang T, Shi Q, Deng Z, Lin S.	Front Microbiol	10.3389/fmicb.2023.1182449	2023
	Biogenic Synthesis of Silver Nanoparticles Using Pantoea stewartii and Priestia aryabhattai and Their Antimicrobial, Larvicidal, Histopathological, and Biotoxicity Potential.	Wilson JJ, Harimuralikrishnaa T, Sivakumar T, Mahendran S, Ponmanickam P, Thangaraj R, Sevarkodiyone S, Alharbi NS, Kadaikunnan S, Venkidasamy B, Thiruvengadam M, Govindasamy R.	Bioengineering (Basel)	10.3390/bioengineering10020248	2023
Metabolism	Continuous production of oxytetracycline in fluidized bed bioreactor by immobilized cells of Streptomyces varsoviensis MTCC-1537: effect of dilution and glucose loading rates.	Jetty A, Potumarthi R, Rao AG, Rao BS, Ramakrishna SV.	Appl Biochem Biotechnol	10.1007/s12010-009-8623-y	2009
	Modifications of diketopiperazines assembled by cyclodipeptide synthases with cytochrome P₄₅₀ enzymes.	Harken L, Li SM.	Appl Microbiol Biotechnol	10.1007/s00253-021-11178-1	2021
	Discovery of Tricyclic Aromatic Polyketides Reveals Hidden Chain-Length Flexibility in Type II Polyketide Synthases.	Liu Y, Wang L, Wang H, Zhu Y, Sun J, Ma B, Liu L, Bao X, Ren J, Fan K, Wang L, Li X, Pan G.	Int J Mol Sci	10.3390/ijms26167801	2025
Enzymology	Volatiles from nineteen recently genome sequenced actinomycetes.	Citron CA, Barra L, Wink J, Dickschat JS.	Org Biomol Chem	10.1039/c4ob02609h	2015
Enzymology	Hygrobafilomycin, a cytotoxic and antifungal macrolide bearing a unique monoalkylmaleic anhydride moiety, from Streptomyces varsoviensis.	Tchize Ndejouong Ble S, Sattler I, Maier A, Kelter G, Menzel KD, Fiebig HH, Hertweck C.	J Antibiot (Tokyo)	10.1038/ja.2010.52	2010
Metabolism	Multi-omic analysis tools for microbial metabolites prediction.	Wu S, Zhou H, Chen D, Lu Y, Li Y, Qiao J.	Brief Bioinform	10.1093/bib/bbae264	2024
Genetics	Global Genome Mining Reveals the Distribution of Diverse Thioamidated RiPP Biosynthesis Gene Clusters.	Malit JJL, Wu C, Liu LL, Qian PY.	Front Microbiol	10.3389/fmicb.2021.635389	2021
Genetics	DiTing: A Pipeline to Infer and Compare Biogeochemical Pathways From Metagenomic and Metatranscriptomic Data.	Xue CX, Lin H, Zhu XY, Liu J, Zhang Y, Rowley G, Todd JD, Li M, Zhang XH.	Front Microbiol	10.3389/fmicb.2021.698286	2021
Pathogenicity	Genome Mining Revealed a High Biosynthetic Potential for Antifungal Streptomyces sp. S-2 Isolated from Black Soot.	Siupka P, Pinski A, Babicka D, Piotrowska-Seget Z.	Int J Mol Sci	10.3390/ijms21072558	2020
Phylogeny	Phylogenetic relationships in the family Streptomycetaceae using multi-locus sequence analysis.	Labeda DP, Dunlap CA, Rong X, Huang Y, Doroghazi JR, Ju KS, Metcalf WW.	Antonie Van Leeuwenhoek	10.1007/s10482-016-0824-0	2017
Genetics	Genome-Based Taxonomic Classification of the Phylum Actinobacteria.	Nouioui I, Carro L, Garcia-Lopez M, Meier-Kolthoff JP, Woyke T, Kyrpides NC, Pukall R, Klenk HP, Goodfellow M, Goker M.	Front Microbiol	10.3389/fmicb.2018.02007	2018
Genetics	Draft genome sequence of Streptomyces tunisialbus DSM 105760(T).	Ayed A, Wibberg D, Zendah El Euch I, Frese M, Limam F, Sewald N	Arch Microbiol	10.1007/s00203-020-01913-z	2020
Pathogenicity	Persipeptides A and B, two cyclic peptides from Streptomyces sp. UTMC 1154.	Mohammadipanah F, Matasyoh J, Hamedi J, Klenk HP, Laatsch H	Bioorg Med Chem	10.1016/j.bmc.2011.10.076	2011
	Phenylacetyl pepstatin inhibitors of aspartyl proteases from Streptomyces varsoviensis.	Ye W, Guo Z	J Antibiot (Tokyo)	10.1038/s41429-022-00542-6	2022
Phylogeny	Streptomyces zagrosensis sp. nov., isolated from soil.	Mohammadipanah F, Hamedi J, Sproer C, Rohde M, Montero-Calasanz MDC, Klenk HP	Int J Syst Evol Microbiol	10.1099/ijs.0.064527-0	2014

References

#9474	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 40346
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20216	Curators of the JMRC: Jena Microbial Resource Collection (JMRC):
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#66794	Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg: BRENDA, the ELIXIR core data resource in 2021: new developments and updates. Nucleic Acids Res. 49: D498 - D508 2020 ( DOI 10.1093/nar/gkaa1025 , PubMed 33211880 )
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68379	Automatically annotated from API Coryne .
#68382	Automatically annotated from API zym .
#69259	Wink, J.: Compendium of Actinobacteria. HZI-Helmholtz-Centre for Infection Research, Braunschweig .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Streptomyces varsoviensis (DSM 40346, ATCC 14631c, ATCC 25505)

Name and taxonomic classification

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Genome browser: GCA_000718635

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