Streptomyces lasalocidi (DSM 46487, IMET 43706, NRRL 3382)

Name: Streptomyces lasalocidi (DSM 46487, IMET 43706, NRRL 3382)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 16010

Type strain

Variant Isotype of BacDive ID 15937

Culture col. no. DSM 46487 IMET 43706 NRRL 3382 CGMCC 4.5634 ATCC 31180 1 more

NCBI tax ID(s) 324833

Special Collections DSMZ JCM Wink compendium

History <- IMET <- NRRL (Streptomyces lasaliensis) NRRL 3382 <-- J. Berger.

Links

Streptomyces lasalocidi DSM 46487 is a mesophilic prokaryote that builds an aerial mycelium and was isolated from Soil in Hyde Park.

mesophilic 16S sequence

Name and taxonomic classification

SI-ID 39928

ATCC 31180,NRRL 3382,DSM 46487,IMET 43706,JCM 3373,DSM 41442

@ref 20215

Last LPSN update 2026-02-09 11:21:51

Domain Bacteria

Phylum Actinomycetota

Class Actinomycetes

Order Kitasatosporales

Family Streptomycetaceae

Genus Streptomyces

Species Streptomyces lasalocidi

Full scientific name Streptomyces lasalocidi Erwin et al. 2020

BacDive ID	Other strains from **Streptomyces lasalocidi** (1)	Type strain
15937	S. lasalocidi X-537, DSM 41442, ATCC 31180, NRRL 3382

Morphology

Cell morphology

@ref	Gram stain	Confidence
125439	positive	99.4

Colony morphology

@ref	Colony color	Medium used
69457	Brown beige (1011), umbra grey (7022)	ISP 4
69457	Brown beige (1011)	suter without tyrosine
69457	Basalt grey (7012), brown beige (1011)	ISP 5
69457	Mouse grey (7005), dusty grey (7037)	ISP 3
69457	Mouse grey (7005), signal grey (7004)	ISP 7
69457	Ochre yellow (1024)	ISP 2
69457	Ochre yellow (1024)	ISP 6
69457	Sepia brown (8014)	suter with tyrosine

Multicellular morphology

@ref	Complex name	Complex color	Medium name
69457	Aerial mycelium	Signal grey (7004)	ISP 2
69457	Aerial mycelium	Grey white (9002)	ISP 3
69457	Aerial mycelium		ISP 4
69457	Aerial mycelium	Signal white (9003)	ISP 5
69457	Aerial mycelium		ISP 6
69457	Aerial mycelium	Signal white (9003)	ISP 7
69457	Aerial mycelium	Cream (9001)	suter with tyrosine
69457	Aerial mycelium	Cream (9001)	suter without tyrosine

Pigmentation

@ref	Production	Color	Name
69457			melanin pigment
69457		Green grey (7009), ochre brown (8001), black brown (8022), ochre yellow (1024)	soluble pigment

Multimedia

@ref:	12577
multimedia content:	DSM_46487.jpg
multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_46487.jpg
caption:	Medium 987 28°C
intellectual property rights:	© Leibniz-Institut DSMZ
manual_annotation:	1

@ref:	69457
multimedia content:	DSM_46487_image3.jpeg
multimedia.multimedia content:	DSM_46487_image3.jpeg
caption:	Plates (65, ISP2, ISP3, ISP4, ISP5, ISP7)
intellectual property rights:	Helmholtz-Zentrum für Infektionsforschung GmbH
manual_annotation:	1

@ref:	69457
multimedia content:	DSM_46487_image4.jpeg
multimedia.multimedia content:	DSM_46487_image4.jpeg
caption:	Plates (65, ISP2, ISP3, ISP4, ISP5, ISP7)
intellectual property rights:	Helmholtz-Zentrum für Infektionsforschung GmbH
manual_annotation:	1

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
12577	GYM STREPTOMYCES MEDIUM (DSMZ Medium 65)	Medium recipe at MediaDive	Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 18.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water
12577	ROLLED OATS MINERAL MEDIUM (DSMZ Medium 84)	Medium recipe at MediaDive	Name: ROLLED OATS MINERAL MEDIUM (DSMZ Medium 84) Composition: Agar 20.0 g/l Rolled oats 20.0 g/l ZnSO4 x 7 H2O 0.001 g/l MnCl2 x 4 H2O 0.001 g/l FeSO4 x 7 H2O 0.001 g/l Distilled water
12577	ISP2 MEDIUM (DSMZ Medium 987)	Medium recipe at MediaDive	Name: ISP2 MEDIUM (DSMZ Medium 987) Composition: Agar 20.0 g/l Malt extract 10.0 g/l Dextrose 4.0 g/l Yeast extract 4.0 g/l Distilled water

Culture temp

@ref	Growth	Type	Temperature (°C)	Range
12577	positive	growth	28	mesophilic
67770	positive	growth	28	mesophilic

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
125439	obligate aerobe	100

Compound production

@ref	Compound
12577	X-537 A
67770	Lasalocids A (antibiotic X-537 A), B, C, D, E and iso-lasalocid A

Halophily

@ref	Salt	Growth	Tested relation	Concentration
69457	NaCl	positive	growth	0-10 %

Observation

67770

Observationquinones: MK-9(H₄), MK-9(H₆), MK-9(H₈)

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
69457	22599 ChEBI	arabinose	+	growth
69457	62968 ChEBI	cellulose	+/-	growth
68379	17634 ChEBI	D-glucose	-	fermentation	from API Coryne
68379	16899 ChEBI	D-mannitol	-	fermentation	from API Coryne
68379	16988 ChEBI	D-ribose	-	fermentation	from API Coryne
68379	65327 ChEBI	D-xylose	-	fermentation	from API Coryne
68379	4853 ChEBI	esculin	-	hydrolysis	from API Coryne
69457	28757 ChEBI	fructose	+	growth
68379	5291 ChEBI	gelatin	+	hydrolysis	from API Coryne
69457	17234 ChEBI	glucose	+	growth
68379	28087 ChEBI	glycogen	-	fermentation	from API Coryne
69457	17268 ChEBI	inositol	+	growth
68379	17716 ChEBI	lactose	-	fermentation	from API Coryne
68379	17306 ChEBI	maltose	-	fermentation	from API Coryne
69457	37684 ChEBI	mannose	+	growth
68379	17632 ChEBI	nitrate	-	reduction	from API Coryne
69457	16634 ChEBI	raffinose	+/-	growth
69457	26546 ChEBI	rhamnose	+/-	growth
68379	17992 ChEBI	sucrose	-	fermentation	from API Coryne
69457	17992 ChEBI	sucrose	+/-	growth
68379	16199 ChEBI	urea	-	hydrolysis	from API Coryne
69457	18222 ChEBI	xylose	+	growth

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
68382	alkaline phosphatase	+	3.1.3.1	from API zym
68379	alkaline phosphatase	+	3.1.3.1	from API Coryne
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68379	alpha-glucosidase	-	3.2.1.20	from API Coryne
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68382	beta-galactosidase	+	3.2.1.23	from API zym
68379	beta-galactosidase	+	3.2.1.23	from API Coryne
68382	beta-glucosidase	-	3.2.1.21	from API zym
68379	beta-glucosidase	-	3.2.1.21	from API Coryne
68382	beta-glucuronidase	-	3.2.1.31	from API zym
68379	beta-glucuronidase	-	3.2.1.31	from API Coryne
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
68379	gelatinase	+		from API Coryne
68382	leucine arylamidase	+	3.4.11.1	from API zym
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68379	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API Coryne
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
68379	pyrazinamidase	-	3.5.1.B15	from API Coryne
68379	pyrrolidonyl arylamidase	+	3.4.19.3	from API Coryne
68382	trypsin	-	3.4.21.4	from API zym
68379	urease	-	3.5.1.5	from API Coryne

API coryne

@ref	Reduction of nitrateNIT	PYZ	PYRA	PAL	beta GUR	beta GAL	alpha GLU	beta NAG	ESC	URE	GEL	Control fermentationControl	GLU	RIB	XYL	MAN	MAL	LAC	SAC	GLYG	CAT
69457	-	-	+	+	-	+	-	-	-	-	+	not determinedn.d.	-	-	-	-	-	-	-	-	not determinedn.d.

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
69457	not determinedn.d.	+	+	+	+/-	+	+/-	+/-	-	+/-	+	+	-	+	-	+/-	-	-	-	-

Isolation, sampling and environmental information

Isolation

@ref	Sample type	Geographic location	Country	Country ISO 3 Code	Continent
67770	Soil in Hyde Park	MA	USA	USA	North America

Interaction and safety

Sequence information

Genome sequences

@ref	Description	Assembly level	IMG accession	NCBI tax ID	Score
66792	Streptomyces lasalocidi ATCC 31180	complete	651716584	324833	91.57
66792	Streptomyces lasalocidi ATCC 31180	complete	651716557	324833	84.11

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
12577	Streptomyces lasalocidi strain ATCC 31180 16S ribosomal RNA gene, partial sequence	MK852399	1521		324833
67770	Streptomyces lasaliensis strain JCM 3373 16S ribosomal RNA gene, partial sequence	HQ537060	1387		324833

GC content

@ref	GC-content (mol%)	Method
67770	72.6	genome sequence analysis

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Streptomyces lasalocidi ATCC 31180
IMG: 651716557

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	yes	82.10	no
125439	motility	BacteriaNetⓘ	no	80.60	no
125439	gram_stain	BacteriaNetⓘ	positive	99.40	no
125439	oxygen_tolerance	BacteriaNetⓘ	obligate aerobe	100.00	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	Structural Basis of Sequential Enantioselective Epoxidation by a Flavin-Dependent Monooxygenase in Lasalocid A Biosynthesis.	Wang Q, Deng Y, Viera D, Liu X, Liu N, Hu Y, Hu X, Wei H, Zhou Q, Lan T, He W, Chen X, Kim CY.	Angew Chem Int Ed Engl	10.1002/anie.202504982	2025
	Comparative and Functional Analyses Reveal Conserved and Variable Regulatory Systems That Control Lasalocid Biosynthesis in Different Streptomyces Species.	Liu M, Wang K, Wei J, Liu N, Niu G, Tan H, Huang Y.	Microbiol Spectr	10.1128/spectrum.03852-22	2023
	A novel PGPR strain, Streptomyces lasalocidi JCM 3373^T, alleviates salt stress and shapes root architecture in soybean by secreting indole-3-carboxaldehyde.	Lu L, Liu N, Fan Z, Liu M, Zhang X, Tian J, Yu Y, Lin H, Huang Y, Kong Z.	Plant Cell Environ	10.1111/pce.14847	2024
	Modulation of plant transcription factors and priming of stress tolerance by plant growth-promoting bacteria: a systematic review.	Kaleh AM, Singh P, Ooi Chua K, Harikrishna JA.	Ann Bot	10.1093/aob/mcae166	2025
Phylogeny	Streptomyces lasalocidi sp. nov. (formerly 'Streptomyces lasaliensis'), an actinomycete isolated from soil which produces the polyether antibiotic lasalocid.	Erwin GS, Heikkinen J, Halimaa P, Haber CL	Int J Syst Evol Microbiol	10.1099/ijsem.0.004135	2020

References

#12577	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 46487
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68379	Automatically annotated from API Coryne .
#68382	Automatically annotated from API zym .
#69457	Wink, J.: Compendium of Actinobacteria. HZI-Helmholtz-Centre for Infection Research, Braunschweig .
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Streptomyces lasalocidi (DSM 46487, IMET 43706, NRRL 3382)

Name and taxonomic classification

Morphology

Cell morphology

Colony morphology

Multicellular morphology

Pigmentation

Multimedia

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Compound production

Halophily

Observation

Metabolite utilization

Enzymes

API coryne

API zym

Isolation, sampling and environmental information

Isolation

Interaction and safety

Sequence information

Genome sequences

16S sequences

GC content

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

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