Streptomyces sioyaensis (DSM 40032, ATCC 13989, ATCC 19810)

Cell morphology

Multimedia

• @ref:	9231
  multimedia content:	DSM_40032.jpg
  multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_40032.jpg
  caption:	Medium 65 28°C
  intellectual property rights:	© Leibniz-Institut DSMZ
  manual_annotation:	1

Culture medium

@ref	Name	Growth	Medium link	Composition
9231	GYM STREPTOMYCES MEDIUM (DSMZ Medium 65)		Medium recipe at MediaDive	Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 18.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water
9231	STARCH - MINERAL SALT - AGAR (STMS) (DSMZ Medium 252)		Medium recipe at MediaDive	Name: STARCH - MINERAL SALT - AGAR (STMS) (DSMZ Medium 252) Composition: Agar 14.985 g/l Starch 9.99001 g/l (NH4)2SO4 1.998 g/l CaCO3 1.998 g/l K2HPO4 0.999001 g/l MgSO4 x 7 H2O 0.999001 g/l NaCl 0.999001 g/l FeSO4 x 7 H2O 0.000999001 g/l MnCl2 x 4 H2O 0.000999001 g/l ZnSO4 x 7 H2O 0.000999001 g/l Distilled water

Culture temp

Oxygen tolerance

Spore formation

Compound production

Risk assessment

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	Streptomyces sioyaensis ATCC 13989	complete			2563366712	67364	43.78
67770	ASM412273v1 assembly for Streptomyces sioyaensis DSM 40032	contig	GCA_004122735	67364.4	8033699488	67364	20.8

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
20218	Streptomyces sioyaensis gene for 16S rRNA, partial sequence	AB122743	565		67364
20218	Streptomyces sioyaensis gene for 16S ribosomal RNA, partial sequence, strain: JCM 4418	D44131	121		67364
20218	Streptomyces sioyaensis gene for 16S rRNA, partial sequence, strain: NBRC 12820	AB184171	1465		67364
20218	Streptomyces sioyaensis strain NRRL B-5408 16S ribosomal RNA gene, partial sequence	DQ026654	1489		67364
124043	Streptomyces sioyaensis strain DSM 40032 16S ribosomal RNA gene, partial sequence.	MH628441	1510		67364

Predictions

Literature

Topic	Title	Authors	Journal	DOI	Year
	Comparative genomics reveals environmental adaptability and antimicrobial activity of a novel Streptomyces isolated from soil under black Gobi rocks.	Wen Y, Zhang B, Zhang G, Wu M, Chen X, Chen T, Liu G, Zhang W.	Antonie Van Leeuwenhoek	10.1007/s10482-023-01882-5	2023
Genetics	Whole genome sequencing of Streptomyces actuosus ISP-5337, Streptomyces sioyaensis B-5408, and Actinospica acidiphila B-2296 reveals secondary metabolomes with antibiotic potential.	Majer HM, Ehrlich RL, Ahmed A, Earl JP, Ehrlich GD, Beld J.	Biotechnol Rep (Amst)	10.1016/j.btre.2021.e00596	2021
	Integrating Metabolomics and Genomics to Uncover Antimicrobial Compounds in Lactiplantibacillus plantarum UTNGt2, a Cacao-Originating Probiotic from Ecuador.	Molina D, Angamarca E, Marinescu GC, Popescu RG, Tenea GN.	Antibiotics (Basel)	10.3390/antibiotics14020123	2025
Metabolism	Use of direct-infusion electrospray mass spectrometry to guide empirical development of improved conditions for expression of secondary metabolites from actinomycetes.	Zahn JA, Higgs RE, Hilton MD.	Appl Environ Microbiol	10.1128/aem.67.1.377-386.2001	2001
	Induction of Fungal Secondary Metabolites by Co-Culture with Actinomycete Producing HDAC Inhibitor Trichostatins.	Hwang GJ, Roh J, Son S, Lee B, Jang JP, Hur JS, Hong YS, Ahn JS, Ko SK, Jang JH.	J Microbiol Biotechnol	10.4014/jmb.2301.01017	2023
Pathogenicity	Resistance to thiostrepton, siomycin, and sporangiomycin in actinomycetes that produce them.	Thompson J, Cundliffe E.	J Bacteriol	10.1128/jb.142.2.455-461.1980	1980
	The antagonistic mechanisms of Streptomyces sioyaensis on the growth and metabolism of poplar canker pathogen Valsa sordida	Li Lm, Zheng T, Chen Y, Sui Y, Ding R, Hou L, Zheng F, Zhu C.	Biol Control	10.1016/j.biocontrol.2020.104392	2020
	Identification and structural analysis of a thermophilic beta-1,3-glucanase from compost.	Feng J, Xu S, Feng R, Kovalevsky A, Zhang X, Liu D, Wan Q.	Bioresour Bioprocess	10.1186/s40643-021-00449-4	2021
	Structure-function analysis of carrier protein-dependent 2-sulfamoylacetyl transferase in the biosynthesis of altemicidin.	Zhu Y, Mori T, Karasawa M, Shirai K, Cheng W, Terada T, Awakawa T, Abe I.	Nat Commun	10.1038/s41467-024-55265-z	2024
Genetics	A novel acidic laminarinase derived from Jermuk hot spring metagenome.	Paloyan A, Soghomonyan T, Karapetyan M, Grigoryan H, Kruger A, Cuskin F, Marles-Wright J, Burkhardt C, Antranikian G.	Appl Microbiol Biotechnol	10.1007/s00253-025-13557-4	2025
	Diversity and antimicrobial activity of the tropical ant-derived actinomycetes isolated from Thailand.	Tunvongvinis T, Jaitrong W, Samung Y, Tanasupawat S, Phongsopitanun W.	AIMS Microbiol	10.3934/microbiol.2024005	2024
	Utilization of rhizospheric Streptomyces for biological control of Rigidoporus sp. causing white root disease in rubber tree	Nakaew N, Rangjaroen C, Sungthong R.	Eur J Plant Pathol	10.1007/s10658-015-0592-0	2015
Metabolism	Effect of Potato Glycoside Alkaloids on Energy Metabolism of Fusarium solani.	Zhang C, Ding D, Wang B, Wang Y, Li N, Li R, Yan Y, He J.	J Fungi (Basel)	10.3390/jof9070777	2023
	[Diversity of genes encoding nonribosomal peptide synthetases in the Streptomyces sioyaensis genome].	Mironovskii ML, Ostash BE, Fedorenko VA.	Genetika	10.1134/s1022795410070033	2010
Metabolism	Identification, Cloning and Heterologous Expression of the Gene Cluster Directing RES-701-3, -4 Lasso Peptides Biosynthesis from a Marine Streptomyces Strain.	Oves-Costales D, Sanchez-Hidalgo M, Martin J, Genilloud O.	Mar Drugs	10.3390/md18050238	2020
	GH-16 Type beta-1,3-Glucanase from Lysobacter sp. MK9-1 Enhances Antifungal Activity of GH-19 Type Chitinase, and Its Glucan-binding Domain Binds to Fungal Cell-wall.	Otsuka Y, Sato K, Yano S, Kanno H, Suyotha W, Konno H, Makabe K, Taira T.	J Appl Glycosci (1999)	10.5458/jag.jag.jag-2022_0002	2022
	The 1.5 A structure of endo-1,3-beta-glucanase from Streptomyces sioyaensis: evolution of the active-site structure for 1,3-beta-glucan-binding specificity and hydrolysis.	Hong TY, Hsiao YY, Meng M, Li TT.	Acta Crystallogr D Biol Crystallogr	10.1107/s0907444908021550	2008
Metabolism	Streptomyces from traditional medicine: sources of new innovations in antibiotic discovery.	Quinn GA, Banat AM, Abdelhameed AM, Banat IM.	J Med Microbiol	10.1099/jmm.0.001232	2020
	Gastric coinfection with thiopeptide-positive Cutibacterium acnes decreases FOXM1 and pro-inflammatory biomarker expression in a murine model of Helicobacter pylori-induced gastric cancer.	Lunger C, Shen Z, Holcombe H, Mannion AJ, Dzink-Fox J, Kurnick S, Feng Y, Muthupalani S, Carrasco SE, Wilson KT, Peek RM, Piazuelo MB, Morgan DR, Armijo AL, Mammoliti M, Wang TC, Fox JG.	Microbiol Spectr	10.1128/spectrum.03450-23	2024
Phylogeny	Proposal to reclassify the Streptomyces albidoflavus clade on the basis of multilocus sequence analysis and DNA-DNA hybridization, and taxonomic elucidation of Streptomyces griseus subsp. solvifaciens.	Rong X, Guo Y, Huang Y.	Syst Appl Microbiol	10.1016/j.syapm.2009.05.003	2009
Enzymology	A Novel Glycoside Hydrolase Family 5 beta-1,3-1,6-Endoglucanase from Saccharophagus degradans 2-40T and Its Transglycosylase Activity.	Wang D, Kim DH, Seo N, Yun EJ, An HJ, Kim JH, Kim KH.	Appl Environ Microbiol	10.1128/aem.00635-16	2016
	Effects and mechanism of siomycin A on the growth and apoptosis of MiaPaCa-2 cancer cells.	Wang B, Wang W, Meng HY, Chen J, Yuan LJ.	Oncol Lett	10.3892/ol.2019.10633	2019
Metabolism	Isolation and biochemical characterization of an endo-1,3-beta-glucanase from Streptomyces sioyaensis containing a C-terminal family 6 carbohydrate-binding module that binds to 1,3-beta-glucan.	Hong TY, Cheng CW, Huang JW, Meng M.	Microbiology (Reading)	10.1099/00221287-148-4-1151	2002
Enzymology	Biochemical characterization and antifungal activity of an endo-1,3-beta-glucanase of Paenibacillus sp. isolated from garden soil.	Hong TY, Meng M.	Appl Microbiol Biotechnol	10.1007/s00253-003-1249-z	2003
Phylogeny	Phylogenetic relationships in the family Streptomycetaceae using multi-locus sequence analysis.	Labeda DP, Dunlap CA, Rong X, Huang Y, Doroghazi JR, Ju KS, Metcalf WW.	Antonie Van Leeuwenhoek	10.1007/s10482-016-0824-0	2017
Phylogeny	Altemicidin, a new acaricidal and antitumor substance. I. Taxonomy, fermentation, isolation and physico-chemical and biological properties.	Takahashi A, Kurasawa S, Ikeda D, Okami Y, Takeuchi T.	J Antibiot (Tokyo)	10.7164/antibiotics.42.1556	1989
Metabolism	Functional Analysis of a Novel beta-(1,3)-Glucanase from Corallococcus sp. Strain EGB Containing a Fascin-Like Module.	Zhou J, Li Z, Wu J, Li L, Li D, Ye X, Luo X, Huang Y, Cui Z, Cao H.	Appl Environ Microbiol	10.1128/aem.01016-17	2017
	Transglutaminases in Dysbiosis As Potential Environmental Drivers of Autoimmunity.	Lerner A, Aminov R, Matthias T.	Front Microbiol	10.3389/fmicb.2017.00066	2017
Metabolism	Aminoacyl sulfonamide assembly in SB-203208 biosynthesis.	Hu Z, Awakawa T, Ma Z, Abe I.	Nat Commun	10.1038/s41467-018-08093-x	2019
	Proteasome inhibitor bortezomib enhances the effect of standard chemotherapy in small cell lung cancer.	Taromi S, Lewens F, Arsenic R, Sedding D, Sanger J, Kunze A, Mobs M, Benecke J, Freitag H, Christen F, Kaemmerer D, Lupp A, Heilmann M, Lammert H, Schneider CP, Richter K, Hummel M, Siegmund B, Burger M, Briest F, Grabowski P.	Oncotarget	10.18632/oncotarget.21221	2017
	Rerouting the Pathway for the Biosynthesis of the Side Ring System of Nosiheptide: The Roles of NosI, NosJ, and NosK.	Badding ED, Grove TL, Gadsby LK, LaMattina JW, Boal AK, Booker SJ.	J Am Chem Soc	10.1021/jacs.7b01497	2017
Metabolism	Histone deacetylase inhibitors and pancreatic cancer: are there any promising clinical trials?	Koutsounas I, Giaginis C, Theocharis S.	World J Gastroenterol	10.3748/wjg.v19.i8.1173	2013
Metabolism	Identification of the thiazolyl peptide GE37468 gene cluster from Streptomyces ATCC 55365 and heterologous expression in Streptomyces lividans.	Young TS, Walsh CT.	Proc Natl Acad Sci U S A	10.1073/pnas.1110435108	2011
Metabolism	Identification and characterization of the Streptomyces globisporus 1912 regulatory gene lndYR that affects sporulation and antibiotic production.	Ostash B, Rebets Y, Myronovskyy M, Tsypik O, Ostash I, Kulachkovskyy O, Datsyuk Y, Nakamura T, Walker S, Fedorenko V.	Microbiology (Reading)	10.1099/mic.0.045088-0	2011
Metabolism	Stimulative effect of elemental sulfur on siomycin production by Streptomyces sioyaensis.	Yagi S, Kitai S, Kimura T.	Appl Microbiol	10.1128/am.22.2.153-156.1971	1971
Metabolism	Oxidation of elemental sulfur to thiosulfate by Streptomyces.	Yagi S, Kitai S, Kimura T.	Appl Microbiol	10.1128/am.22.2.157-159.1971	1971
Metabolism	Current evidence for histone deacetylase inhibitors in pancreatic cancer.	Koutsounas I, Giaginis C, Patsouris E, Theocharis S.	World J Gastroenterol	10.3748/wjg.v19.i6.813	2013
Genetics	Complete genome of the cellulolytic thermophile Acidothermus cellulolyticus 11B provides insights into its ecophysiological and evolutionary adaptations.	Barabote RD, Xie G, Leu DH, Normand P, Necsulea A, Daubin V, Medigue C, Adney WS, Xu XC, Lapidus A, Parales RE, Detter C, Pujic P, Bruce D, Lavire C, Challacombe JF, Brettin TS, Berry AM.	Genome Res	10.1101/gr.084848.108	2009
	Comparative genomics and transcriptomics of Propionibacterium acnes.	Brzuszkiewicz E, Weiner J, Wollherr A, Thurmer A, Hupeden J, Lomholt HB, Kilian M, Gottschalk G, Daniel R, Mollenkopf HJ, Meyer TF, Bruggemann H.	PLoS One	10.1371/journal.pone.0021581	2011
Enzymology	Molecular and biochemical characterization of an endo-beta-1,3-glucanase from the pinewood nematode Bursaphelenchus xylophilus acquired by horizontal gene transfer from bacteria.	Kikuchi T, Shibuya H, Jones JT.	Biochem J	10.1042/bj20042042	2005
Enzymology	Molecular characterization and expression in Escherichia coli of three beta-1,3-glucanase genes from Lysobacter enzymogenes strain N4-7.	Palumbo JD, Sullivan RF, Kobayashi DY.	J Bacteriol	10.1128/jb.185.15.4362-4370.2003	2003
Pathogenicity	Bioactivities and genome insights of a thermotolerant antibiotics-producing Streptomyces sp. TM32 reveal its potentials for novel drug discovery.	Nakaew N, Lumyong S, Sloan WT, Sungthong R	Microbiologyopen	10.1002/mbo3.842	2019
	Genomic and Phenotypic Characterization of Streptomyces sirii sp. nov., Amicetin-Producing Actinobacteria Isolated from Bamboo Rhizospheric Soil.	Zakalyukina YV, Alferova VA, Nikandrova AA, Kiriy AR, Chernyshova AP, Kabilov MR, Baturina OA, Biryukov MV, Sergiev PV, Lukianov DA.	Microorganisms	10.3390/microorganisms12122628	2024
Phylogeny	Streptomyces inhibens sp. nov., a novel actinomycete isolated from rhizosphere soil of wheat (Triticum aestivum L.).	Jin L, Zhao Y, Song W, Duan L, Jiang S, Wang X, Zhao J, Xiang W	Int J Syst Evol Microbiol	10.1099/ijsem.0.003204	2019