Streptomyces chrestomyceticus (DSM 40545, ATCC 14947, CBS 745.72)

Cell morphology

Colony morphology

Multicellular morphology

Multimedia

• @ref:	125669
  multimedia content:	DSM_40820.jpg
  multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_40820.jpg
  caption:	Medium 987 28°C
  intellectual property rights:	© Leibniz-Institut DSMZ
  manual_annotation:	1

Culture medium

@ref	Name	Growth	Medium link	Composition
19474	ISP 2			Name: ISP 2 / Yeast Malt Agar (5265); 5265 Composition Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l Agar 15.0 g/l Preparation: Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.0 Usage: Maintenance and Taxonomy Organisms: All Actinomycetes
19474	ISP 3			Name: ISP 3; 5315 Composition Dog oat flakes 20.0 g/l Trace element solution (5314) 2.5 ml/l Agar 18.0 g/l Preparation: Oat flakes are cooked for 20 minutes, trace element solution and agar are added (in the case of non rolled oat flakes the suspension has to bee filtrated). Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.8 Usage: Maintenance and taxonomy (e.g. SEM As liquid medium for metabolite production) Organisms: All Actinomycetes Trace element solution 5314 Name: Trace element solution 5314; 5314 Composition CaCl2 x H2O 3.0 g/l Fe-III-citrate 1.0 g/l MnSO4 0.2 g/l ZnCl2 0.1 g/l CuSO4 x 5 H2O 0.025 g/l Sodium tetra borate 0.2 g/l CoCl2 x 6 H2O 0.004 g/l Sodium molybdate 0.01 g/l Preparation: Use double destillated water. Sterilisation: 20 minutes at 121°C pH before sterilisation: Usage: Trace element solution for different media Organisms:
19474	ISP 4			Name: ISP 4; DSM 547 Solution I: Difco soluble starch, 10.0 g. Make a paste of the starch with a small amount of cold distilled water and bring to a volume of 500 ml. Solution II: CaCO3 2.0 g K2HPO4 (anhydrous) 1.0 g MgSO4 x 7 H2O 1.0 g NaCl 1.0 g (NH4)2SO4 2.0 g Distilled water 500.0 ml Trace salt solution (see below) 1.0 ml The pH should be between 7.0 and 7.4. Do not adjust if it is within this range. Mix solutions I and II together. Add 20.0 g agar. Liquify agar by steaming at 100°C for 10 to 20 min. Trace element solution: FeSO4 x 7 H2O 0.1 g MnCl2 x 4 H2O 0.1 g ZnSO4 x 7 H2O 0.1 g Distilled water 100.0 ml
19474	ISP 5			Name: ISP 5 (5323) Composition L-Asparagine 1.0 g/l Glycerol 10.0 g/l K2HPO4 1.0 g/l Salt solution (see preparation) 1.0 ml/l Agar 20.0 g/l Preparation: Salt solution 1.0 g FeSO4 x 7 H2O 1.0 g MnCl2 x 4 H2O 1.0 g ZNSO4 x 7 H2O in 100 ml water Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.2 Usage: Maintenance and taxonomy Organisms: All Actinomycetes
19474	ISP 6			Name: ISP 6 (5318) Composition Peptone 15.0 g/l Proteose peptose 5.0 g/l Ferric ammonium citrate 0.5 g/l Sodium glycerophosphate 1.0 g/l Sodium thiosulfate 0.08 g/l Yeast extract 1.0 g/l Agar 15.0 g/l Sterilisation: 20 minutes at 121°C pH before sterilisation: Usage: Production of melanoid pigments Organisms: All Actinomycetes
19474	ISP 7			Name: ISP 7 (5322) Composition Glycerol 15.0 g/l L-Tyrosine 0.5 g/l L-Asparagine 1.0 g/l K2HPO4 0.5 g/l NaCl 0.5 g/l FeSO4 x 7 H2O 0.01 g/l Trace element solution 5343 1.0 ml/l Agar 20.0 Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.3 Usage: Production of melanoid pigments Organisms: All Actinomycetes
125669	GYM STREPTOMYCES MEDIUM (DSMZ Medium 65)		Medium recipe at MediaDive	Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 20.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water
125669	ROLLED OATS MINERAL MEDIUM (DSMZ Medium 84)		Medium recipe at MediaDive	Name: ROLLED OATS MINERAL MEDIUM (DSMZ Medium 84) Composition: Agar 20.0 g/l Rolled oats 20.0 g/l ZnSO4 x 7 H2O 0.001 g/l MnCl2 x 4 H2O 0.001 g/l FeSO4 x 7 H2O 0.001 g/l Distilled water

Culture temp

Oxygen tolerance

Spore formation

Compound production

Halophily

Tolerance

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
19474	22599 ChEBI	arabinose	-
68368	29016 ChEBI	arginine	+	hydrolysis	from API 20E
68368	16947 ChEBI	citrate	+	assimilation	from API 20E
19474	28757 ChEBI	fructose	+
68368	5291 ChEBI	gelatin	+	hydrolysis	from API 20E
19474	17234 ChEBI	glucose	+
68368	25094 ChEBI	lysine	+	degradation	from API 20E
19474	29864 ChEBI	mannitol	+
19474	17268 ChEBI	myo-inositol	-
68368	18257 ChEBI	ornithine	+	degradation	from API 20E
19474	16634 ChEBI	raffinose	-
19474	26546 ChEBI	rhamnose	-
19474	17992 ChEBI	sucrose	-
68368	27897 ChEBI	tryptophan	-	energy source	from API 20E
68368	16199 ChEBI	urea	+	hydrolysis	from API 20E
19474	18222 ChEBI	xylose	-

Metabolite production

@ref	Chebi-ID	Metabolite	Production
68368	15688 ChEBI	acetoin		from API 20E
68368	16136 ChEBI	hydrogen sulfide		from API 20E
68368	35581 ChEBI	indole		from API 20E
67770		neomycin E
67770		neomycin F

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test	Indole test
68368	15688 ChEBI	acetoin	+		from API 20E
68368	35581 ChEBI	indole		-	from API 20E

Enzymes

@ref	Value	Activity	Ec
68368	arginine dihydrolase	+	3.5.3.6	from API 20E
68368	beta-galactosidase	+	3.2.1.23	from API 20E
68368	gelatinase	+		from API 20E
68368	lysine decarboxylase	+	4.1.1.18	from API 20E
68368	ornithine decarboxylase	+	4.1.1.17	from API 20E
68368	tryptophan deaminase	+	4.1.99.1	from API 20E
68368	urease	+	3.5.1.5	from API 20E

API 20E

Isolation

Risk assessment

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
67770	ASM386513v1 assembly for Streptomyces chrestomyceticus JCM 4735 NBRC 13444	contig	GCA_003865135	1306181.8	8110891463	1306181	76.37
66792	ASM131546v1 assembly for Streptomyces chrestomyceticus JCM 4735	contig	GCA_001315465	1306181.9	2734481989	1306181	0

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
20218	Streptomyces chrestomyceticus strain CGMCC 4.1657 16S ribosomal RNA gene, partial sequence	JN566025	1378		1306181
20218	Streptomyces chrestomyceticus 16S rRNA gene, type strain DSM 40545T	AJ621609	1497		1306181
20218	Streptomyces chrestomyceticus gene for 16S ribosomal RNA, partial sequence, strain: JCM 4735	D44319	121		1306181
20218	Streptomyces chrestomyceticus gene for 16S rRNA, partial sequence, strain: NBRC 13444	AB184407	1480		1306181
20218	Streptomyces chrestomyceticus JCM 4735 strain NRRL B-3293 16S ribosomal RNA gene, partial sequence	DQ026633	1483		1306181
20218	Streptomyces chrestomyceticus JCM 4735 strain NRRL B-3310 16S ribosomal RNA gene, partial sequence	AY999795	1457		1306181

GC content

Predictions

Literature

Topic	Title	Authors	Journal	DOI	Year
Biotechnology	An Evaluation of the Antibacterial, Antileishmanial, and Cytotoxic Potential of the Secondary Metabolites of Streptomyces sp. ARH (A3).	de Azevedo VLS, Rosa FC, Dias LRL, Batista LA, Melo MC, Sales LAT, Branco AJM, Araujo TRR, de Miranda RCM, Alianca ASDS.	Microorganisms	10.3390/microorganisms12030476	2024
Genetics	Isolated from Populus euphratica rhizosphere soil, and mining their metabolites.	Zhang JX, Chen YH, Luo X, Zhang LL, Luo XX.	Front Microbiol	10.3389/fmicb.2025.1530786	2025
	alpha-Tomatine degradation to tomatidine by food-related Aspergillus species belonging to the section Nigri.	Hui CW, Kishino S, Nakatani Y, Ogawa J.	Biosci Biotechnol Biochem	10.1093/bbb/zbad031	2023
	Revision of the Formycin A and Pyrazofurin Biosynthetic Pathways Reveals Specificity for d-Glutamic Acid and a Cryptic N-Acylation Step During Pyrazole Core Formation.	Zheng Z, Ren D, Ko Y, Liu HW.	J Am Chem Soc	10.1021/jacs.5c01277	2025
Genetics	Draft genome dataset of Streptomyces griseoincarnatus strain R-35 isolated from tidal pool sediments.	Mitchell DD, Vreulink JM, Prins A, Le Roes-Hill M.	Data Brief	10.1016/j.dib.2024.111235	2025
Metabolism	Production of glycerol by Lactobacillus plantarum NRRL B-4496 and formation of hexamine during fermentation of pea protein enriched flour.	Kryachko Y, Batbayar B, Tanaka T, Nickerson MT, Korber DR.	J Biotechnol	10.1016/j.jbiotec.2020.09.009	2020
	Growth and viability of Lactobacillus acidophilus NRRL B-4495, Lactobacillus casei NRRL B-1922 and Lactobacillus plantarum NRRL B-4496 in milk supplemented with cysteine, ascorbic acid and tocopherols	Soto RI, Jimenez Munguia MT, Mani-Lopez E, Palou E, Lopez-Malo A.	Int Dairy J	10.1016/j.idairyj.2019.05.003	2019
	Growth kinetics and lactic acid production of Lactobacillus plantarum NRRL B-4496, L. acidophilus NRRL B-4495, and L. reuteri B-14171 in media containing egg white hydrolysates	Mis Solval K, Chouljenko A, Chotiko A, Sathivel S.	Lebensm Wiss Technol	10.1016/j.lwt.2019.01.058	2019
	Unravelling the outcome of L-glutaminase produced by Streptomyces sp. strain 5 M as an anti-neoplasm activity.	Hassan MG, El-Sayyad GS, Abdel-Monem MO, Malash MN, Kishk MA, El Awady ME, El-Khonezy MI.	Microb Cell Fact	10.1186/s12934-024-02606-8	2025
	Discovery of a Novel Chromone Enantiomer and the Precursors of Nonactic Acid from the Coral-Reef-Derived Streptomyces sp. SCSIO 66814.	Ding W, Li Y, Li X, Yin J, Shi S, Tian X, Zhang S, Yin H.	Mar Drugs	10.3390/md22040181	2024
	Antioxidant and Enzyme Inhibitory Potential of Streptomyces sp. G-18 Grown in Various Media.	Ashok GC, Prakash Pradhan S, Kumar Karki K, Khadka A, Bhandari A, Prasad Pandey B.	Int J Microbiol	10.1155/2023/6439466	2023
Phylogeny	A Novel Strain of the Cyanobacterial Growth-promoting Bacterium, Rhodococcus sp. AF2108, Enhances the Growth of Synechococcus elongatus.	Tan PY, Kato Y, Konishi M.	Microbes Environ	10.1264/jsme2.me24050	2024
Metabolism	Discovery of Key Dioxygenases that Diverged the Paraherquonin and Acetoxydehydroaustin Pathways in Penicillium brasilianum.	Matsuda Y, Iwabuchi T, Fujimoto T, Awakawa T, Nakashima Y, Mori T, Zhang H, Hayashi F, Abe I.	J Am Chem Soc	10.1021/jacs.6b08424	2016
	Effects of enzymatically-extracted purple rice bran fiber as a protectant of L. plantarum NRRL B-4496 during freezing, freeze drying, and storage	Chotiko A, Sathivel S.	Lebensm Wiss Technol	10.1016/j.lwt.2014.05.056	2014
Metabolism	Structure and biosynthesis of scabichelin, a novel tris-hydroxamate siderophore produced by the plant pathogen Streptomyces scabies 87.22.	Kodani S, Bicz J, Song L, Deeth RJ, Ohnishi-Kameyama M, Yoshida M, Ochi K, Challis GL.	Org Biomol Chem	10.1039/c3ob40536b	2013
Pathogenicity	Influence of fungal elicitors on biosynthesis of natamycin by Streptomyces natalensis HW-2.	Wang D, Yuan J, Gu S, Shi Q.	Appl Microbiol Biotechnol	10.1007/s00253-013-4786-0	2013
	Characterization and identification of partial amino acid sequence of a novel elastase inhibitor, Asnidin from Aspergillus nidulans.	Okumura Y, Suzukawa M, Uchiya K, Ogawa K, Komori Y, Yamashita N, Nikai T.	Med Mycol J	10.3314/mmj.54.279	2013
Metabolism	Genome shuffling of Streptomyces viridochromogenes for improved production of avilamycin.	Lv XA, Jin YY, Li YD, Zhang H, Liang XL.	Appl Microbiol Biotechnol	10.1007/s00253-012-4322-7	2013
Enzymology	Development of a Highly Sensitive beta-Glucan Detection System Using Scanning Single-Molecule Counting Method.	Adachi Y, Nakata H, Tanabe T, Yamanaka D, Kanno T, Ishibashi KI, Ohno N.	Int J Mol Sci	10.3390/ijms22115977	2021
Genetics	Anti-Vibrio parahaemolyticus compounds from Streptomyces parvus based on Pan-genome and subtractive proteomics.	Liu W, Ou P, Tian F, Liao J, Ma Y, Wang J, Jin X.	Front Microbiol	10.3389/fmicb.2023.1218176	2023
Enzymology	Cloning, expression, and characterization of endoglucanase gene egIV from Trichoderma viride AS 3.3711.	Huang X, Fan J, Yang Q, Chen X, Liu Z, Wang Y, Wang D.	J Microbiol Biotechnol	10.4014/jmb.1107.06064	2012
	Zinc-Solubilizing Streptomyces spp. as Bioinoculants for Promoting the Growth of Soybean (Glycine max (L.) Merrill).	Suriyachadkun C, Chunhachart O, Srithaworn M, Tangchitcharoenkhul R, Tangjitjareonkun J.	J Microbiol Biotechnol	10.4014/jmb.2206.06058	2022
Genetics	Whole genome sequencing of a novel chitinolytic Streptomyces sp. RB7AG reveals it's chitosan production potential: optimization of the process through Taguchi experimental design.	Behera SS, Nivedita S, Das S, Behera HT, Mojumdar A, Ray L.	3 Biotech	10.1007/s13205-023-03613-z	2023
	Metabolome and Microbiome Analysis to Study the Flavor of Summer Black Tea Improved by Stuck Fermentation.	Wen L, Sun L, Chen R, Li Q, Lai X, Cao J, Lai Z, Zhang Z, Li Q, Song G, Sun S, Cao F.	Foods	10.3390/foods12183414	2023
Metabolism	Antimicrobial activity of protein-containing fractions isolated from Lactobacillus plantarum NRRL B-4496 culture.	Arrioja-Breton D, Mani-Lopez E, Bach H, Lopez-Malo A.	Braz J Microbiol	10.1007/s42770-020-00266-5	2020
Metabolism	Physicochemical characters of a tyrosinase inhibitor produced by Streptomyces roseolilacinus NBRC 12815.	Nakashima T, Anzai K, Kuwahara N, Komaki H, Miyadoh S, Harayama S, Tianero MD, Tanaka J, Kanamoto A, Ando K.	Biol Pharm Bull	10.1248/bpb.32.832	2009
Metabolism	Whole-genome sequencing and analysis of Streptomyces strains producing multiple antinematode drugs.	Yi JS, Kim JM, Kang MK, Kim JH, Cho HS, Ban YH, Song MC, Son KH, Yoon YJ.	BMC Genomics	10.1186/s12864-022-08847-4	2022
Metabolism	Medium optimization based on statistical methodologies for pristinamycins production by Streptomyces pristinaespiralis.	Jia B, Jin ZH, Mei LH.	Appl Biochem Biotechnol	10.1007/s12010-007-8012-3	2008
Genetics	Complete genome sequencing and in silico genome mining reveal the promising metabolic potential in Streptomyces strain CS-7.	Alam K, Hao J, Zhong L, Fan G, Ouyang Q, Islam MM, Islam S, Sun H, Zhang Y, Li R, Li A.	Front Microbiol	10.3389/fmicb.2022.939919	2022
Metabolism	Identification of the C-Glycoside Synthases during Biosynthesis of the Pyrazole-C-Nucleosides Formycin and Pyrazofurin.	Ren D, Wang SA, Ko Y, Geng Y, Ogasawara Y, Liu HW.	Angew Chem Int Ed Engl	10.1002/anie.201910356	2019
	Fermented yellow mombin juice using Lactobacillus acidophilus NRRL B-4495: Chemical composition, bioactive properties and survival in simulated gastrointestinal conditions.	Ribeiro ESS, Damasceno KSFSC, Dantas LMDC, Azevedo WM, Leite PIP, Assis CF, Sousa Junior FC.	PLoS One	10.1371/journal.pone.0239392	2020
	Angucycline-like Aromatic Polyketide from a Novel Streptomyces Species Reveals Freshwater Snail Physa acuta as Underexplored Reservoir for Antibiotic-Producing Actinomycetes.	Safaei N, Mast Y, Steinert M, Huber K, Bunk B, Wink J.	Antibiotics (Basel)	10.3390/antibiotics10010022	2020
	Chemical Ecology of Streptomyces albidoflavus Strain A10 Associated with Carpenter Ant Camponotus vagus.	Baranova AA, Chistov AA, Tyurin AP, Prokhorenko IA, Korshun VA, Biryukov MV, Alferova VA, Zakalyukina YV.	Microorganisms	10.3390/microorganisms8121948	2020
	Safety evaluation of the food enzyme alpha-amylase from the non-genetically modified Aspergillus niger strain AS 29-286.	EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Lambre C, Barat Baviera JM, Bolognesi C, Cocconcelli PS, Crebelli R, Gott DM, Grob K, Lampi E, Mengelers M, Mortensen A, Riviere G, Steffensen IL, Tlustos C, Van Loveren H, Vernis L, Zorn H, Aguilera J, Andryszkiewicz M, Criado A, Fernandez-Fraguas C, Liu Y, Nielsen E, Norby K, di Piazza G, Chesson A.	EFSA J	10.2903/j.efsa.2023.8090	2023
Metabolism	Andean yacon root (Smallanthus sonchifolius Poepp. Endl) fructooligosaccharides as a potential novel source of prebiotics.	Pedreschi R, Campos D, Noratto G, Chirinos R, Cisneros-Zevallos L.	J Agric Food Chem	10.1021/jf0344744	2003
Phylogeny	A Novel Genus of Actinobacterial Tectiviridae.	Caruso SM, deCarvalho TN, Huynh A, Morcos G, Kuo N, Parsa S, Erill I.	Viruses	10.3390/v11121134	2019
	Improved production of Daptomycin in an airlift bioreactor by morphologically modified and immobilized cells of Streptomyces roseosporus.	Chakravarty I, Kundu S.	AMB Express	10.1186/s13568-016-0274-0	2016
	Characterisation of Streptomyces spp. isolated from water-damaged buildings.	Suutari M, Ronka E, Lignell U, Rintala H, Nevalainen A.	FEMS Microbiol Ecol	10.1111/j.1574-6941.2002.tb00908.x	2002
	Multi-Omics-Guided Discovery of Omicsynins Produced by Streptomyces sp. 1647: Pseudo-Tetrapeptides Active Against Influenza A Viruses and Coronavirus HCoV-229E.	Sun H, Li X, Chen M, Zhong M, Li Y, Wang K, Du Y, Zhen X, Gao R, Wu Y, Shi Y, Yu L, Che Y, Li Y, Jiang JD, Hong B, Si S.	Engineering (Beijing)	10.1016/j.eng.2021.05.010	2022
	Effect of Fermentation on the Protein Digestibility and Levels of Non-Nutritive Compounds of Pea Protein Concentrate.	Cabuk B, Nosworthy MG, Stone AK, Korber DR, Tanaka T, House JD, Nickerson MT.	Food Technol Biotechnol	10.17113/ftb.56.02.18.5450	2018
Genetics	Diversification of Secondary Metabolite Biosynthetic Gene Clusters Coincides with Lineage Divergence in Streptomyces.	Choudoir MJ, Pepe-Ranney C, Buckley DH.	Antibiotics (Basel)	10.3390/antibiotics7010012	2018
	The differences and overlaps in the seed-resident microbiome of four Leguminous and three Gramineous forages.	Dai Y, Li XY, Wang Y, Li CX, He Y, Lin HH, Wang T, Ma XR.	Microb Biotechnol	10.1111/1751-7915.13618	2020
	Effect of Lactobacillus plantarum Fermentation on the Surface and Functional Properties of Pea Protein-Enriched Flour.	Cabuk B, Stone AK, Korber DR, Tanaka T, Nickerson MT.	Food Technol Biotechnol	10.17113/ftb.56.03.18.5449	2018
	Cloning and characterization of a regulatory gene of the SARP family and its flanking region from Streptomyces ambofaciens.	Culebras E, Martinez E, Carnero A, Malpartida F.	Mol Gen Genet	10.1007/s004380051135	1999
Phylogeny	Isolation and characterization of a new fructophilic Lactobacillus plantarum FPL strain from honeydew.	Gustaw K, Michalak M, Polak-Berecka M, Wasko A.	Ann Microbiol	10.1007/s13213-018-1350-2	2018
	Biocontrol and plant growth promoting potential of phylogenetically new Streptomyces sp. MR14 of rhizospheric origin.	Kaur T, Rani R, Manhas RK.	AMB Express	10.1186/s13568-019-0849-7	2019
	Antimicrobial Activity and Identification of the Biosynthetic Gene Cluster of X-14952B From Streptomyces sp. 135.	Li N, Chen S, Yan Z, Han J, Ta Y, Pu T, Wang Y.	Front Microbiol	10.3389/fmicb.2021.703093	2021
Metabolism	Comparative Investigation into Formycin A and Pyrazofurin A Biosynthesis Reveals Branch Pathways for the Construction of C-Nucleoside Scaffolds.	Zhang M, Zhang P, Xu G, Zhou W, Gao Y, Gong R, Cai YS, Cong H, Deng Z, Price NPJ, Mao X, Chen W.	Appl Environ Microbiol	10.1128/aem.01971-19	2020
Genetics	Genome Mining of Streptomyces sp. YIM 130001 Isolated From Lichen Affords New Thiopeptide Antibiotic.	Schneider O, Simic N, Aachmann FL, Ruckert C, Kristiansen KA, Kalinowski J, Jiang Y, Wang L, Jiang CL, Lale R, Zotchev SB.	Front Microbiol	10.3389/fmicb.2018.03139	2018
	Efficient Arsenic Methylation and Volatilization Mediated by a Novel Bacterium from an Arsenic-Contaminated Paddy Soil.	Huang K, Chen C, Zhang J, Tang Z, Shen Q, Rosen BP, Zhao FJ.	Environ Sci Technol	10.1021/acs.est.6b01974	2016
Metabolism	Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis.	Nakashima Y, Mori T, Nakamura H, Awakawa T, Hoshino S, Senda M, Senda T, Abe I.	Nat Commun	10.1038/s41467-017-02371-w	2018
Phylogeny	Phylogenetic relationships in the family Streptomycetaceae using multi-locus sequence analysis.	Labeda DP, Dunlap CA, Rong X, Huang Y, Doroghazi JR, Ju KS, Metcalf WW.	Antonie Van Leeuwenhoek	10.1007/s10482-016-0824-0	2017
Metabolism	Analysis of the Pseudouridimycin Biosynthetic Pathway Provides Insights into the Formation of C-nucleoside Antibiotics.	Sosio M, Gaspari E, Iorio M, Pessina S, Medema MH, Bernasconi A, Simone M, Maffioli SI, Ebright RH, Donadio S.	Cell Chem Biol	10.1016/j.chembiol.2018.02.008	2018
	[The effect of 3',5'-cyclic adenylic acid (cAMP) on the growth of bacteria].	Yan RX, Duan KM.	Wei Sheng Wu Xue Bao		1989
	Investigation of Antioxidative and Anticancer Potentials of Streptomyces sp. MUM256 Isolated from Malaysia Mangrove Soil.	Tan LT, Ser HL, Yin WF, Chan KG, Lee LH, Goh BH.	Front Microbiol	10.3389/fmicb.2015.01316	2015
Metabolism	Differential requirement for cathepsin D for processing of the full length and C-terminal fragment of the malaria antigen MSP1.	Tulone C, Sponaas AM, Raiber EA, Tabor AB, Langhorne J, Chain BM.	PLoS One	10.1371/journal.pone.0024886	2011
	Identification and analysis of the paulomycin biosynthetic gene cluster and titer improvement of the paulomycins in Streptomyces paulus NRRL 8115.	Li J, Xie Z, Wang M, Ai G, Chen Y.	PLoS One	10.1371/journal.pone.0120542	2015
Pathogenicity	Biosynthetic pathway for mannopeptimycins, lipoglycopeptide antibiotics active against drug-resistant gram-positive pathogens.	Magarvey NA, Haltli B, He M, Greenstein M, Hucul JA.	Antimicrob Agents Chemother	10.1128/aac.01545-05	2006
	Succession of indigenous Pseudomonas spp. and actinomycetes on barley roots affected by the antagonistic strain Pseudomonas fluorescens DR54 and the fungicide imazalil.	Thirup L, Johnsen K, Winding A.	Appl Environ Microbiol	10.1128/aem.67.3.1147-1153.2001	2001
Metabolism	Microbial transformation of N-methylcolchiceinamide.	Davis PJ.	Antimicrob Agents Chemother	10.1128/aac.19.3.465	1981
Phylogeny	Streptomyces cupreus sp. nov., an antimicrobial producing actinobacterium isolated from Himalayan soil.	Maiti PK, Mandal S.	Arch Microbiol	10.1007/s00203-020-02160-y	2021
Phylogeny	Description of Streptomyces explomaris sp. nov., isolated from the coastal soil rhizosphere of Juniperus excelsa and reclassification of Streptomyces libani as a later heterotypic synonym of Streptomyces nigrescens.	Shu W, Ruckert-Reed C, Gromyko O, Tistechok S, Kalinowski J, Luzhetskyy A, Wittmann C.	Int J Syst Evol Microbiol	10.1099/ijsem.0.006711	2025
Phylogeny	Streptomyces rhizosphaericola sp. nov., an actinobacterium isolated from the wheat rhizosphere.	Vargas Hoyos HA, Nobre Santos S, Da Silva LJ, Paulino Silva FS, Bonaldo Genuario D, Domingues Zucchi T, Melo IS.	Int J Syst Evol Microbiol	10.1099/ijsem.0.003498	2019
Phylogeny	Streptomyces manganisoli sp. nov., a novel actinomycete isolated from manganese-contaminated soil.	Mo P, Zhao J, Li K, Tang X, Gao J.	Int J Syst Evol Microbiol	10.1099/ijsem.0.002762	2018
Phylogeny	Streptomyces solisilvae sp. nov., isolated from tropical forest soil.	Zhou S, Yang X, Huang D, Huang X.	Int J Syst Evol Microbiol	10.1099/ijsem.0.002166	2017
Phylogeny	Streptomyces salilacus sp. nov., an actinomycete isolated from a salt lake.	Luo XX, Gao GB, Xia ZF, Chen ZJ, Wan CX, Zhang LL.	Int J Syst Evol Microbiol	10.1099/ijsem.0.002703	2018
Phylogeny	Streptomyces luozhongensis sp. nov., a novel actinomycete with antifungal activity and antibacterial activity.	Zhang R, Han X, Xia Z, Luo X, Wan C, Zhang L.	Antonie Van Leeuwenhoek	10.1007/s10482-016-0790-6	2017
Phylogeny	Streptomyces canchipurensis sp. nov., isolated from a limestone habitat.	Li WJ, Nimaichand S, Jiang Z, Liu MJ, Khieu TN, Kim CJ, Hozzein WN, Park DJ, Wadaan MA, Ningthoujam DS.	Antonie Van Leeuwenhoek	10.1007/s10482-014-0281-6	2014
Phylogeny	Streptomyces pluripotens sp. nov., a bacteriocin-producing streptomycete that inhibits meticillin-resistant Staphylococcus aureus.	Lee LH, Zainal N, Azman AS, Eng SK, Ab Mutalib NS, Yin WF, Chan KG.	Int J Syst Evol Microbiol	10.1099/ijs.0.065045-0	2014
Phylogeny	Streptomyces chilikensis sp. nov., a halophilic streptomycete isolated from brackish water sediment.	Ray L, Suar M, Pattnaik AK, Raina V.	Int J Syst Evol Microbiol	10.1099/ijs.0.046284-0	2013
Phylogeny	Streptomyces aridus sp. nov., isolated from a high altitude Atacama Desert soil and emended description of Streptomyces noboritoensis Isono et al. 1957.	Idris H, Labeda DP, Nouioui I, Castro JF, Del Carmen Montero-Calasanz M, Bull AT, Asenjo JA, Goodfellow M.	Antonie Van Leeuwenhoek	10.1007/s10482-017-0838-2	2017
Phylogeny	Streptomyces kebangsaanensis sp. nov., an endophytic actinomycete isolated from an ethnomedicinal plant, which produces phenazine-1-carboxylic acid.	Sarmin NIM, Tan GYA, Franco CMM, Edrada-Ebel R, Latip J, Zin NM	Int J Syst Evol Microbiol	10.1099/ijs.0.047878-0	2013