Streptomyces prasinus (DSM 40744, ATCC 13879, CBS 780.72)

Name: Streptomyces prasinus (DSM 40744, ATCC 13879, CBS 780.72)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 15047

Type strain

Strain Designation FH 1280, FH 3263, FH3263, FH1280

Culture col. no. DSM 40744 ATCC 13879 CBS 780.72 DSM 40590 IFO 13479 17 more

NCBI tax ID(s) 67345

Special Collections DSMZ JCM KCTC Wink compendium

History DSMZ <- Hoechst AG; FH 1280 JCM <-- KCC S-0728 <-- IFO 13479 <-- SAJ <-- ISP 5590 <-- ATCC 13879 <-- Farbwerke Hoechst AG strain FH 3263.

Links

Streptomyces prasinus FH 1280 is a bacterium that builds an aerial mycelium and produces antibiotic compounds.

antibiotic compound production genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 13325

LMG 19299,ATCC 13879,IFO 13479,JCM 4728,NRRL B-12101,NRRL B-12521,VKM Ac-975,CBS 780.72,AS 4.1439,CECT 3211,KCTC 9019,NBRC 13479,DSM 40744,BCRC 16216,CCRC 16216,NBIMCC 66,CGMCC 4.1439,DSM 40590

@ref 20215

Last LPSN update 2026-05-29 08:28:26

Domain Bacteria

Phylum Actinomycetota

Class Actinomycetes

Order Kitasatosporales

Family Streptomycetaceae

Genus Streptomyces

Species Streptomyces prasinus

Full scientific name Streptomyces prasinus Ettlinger et al. 1958 (Approved Lists 1980)

Synonyms (1)

Streptomyces bambergiensis

BacDive ID	Other strains from **Streptomyces prasinus** (3)	Type strain
15483	S. prasinus DSM 40099, ATCC 19800, CBS 552.68, ETH 13815, ... (type strain)
15484	S. prasinus FAL K517, DSM 40688
15485	S. prasinus M-3103 (SC 3/68), DSM 40774, ATCC 15825, ...

Morphology

Cell morphology

@ref	Motility	Confidence	Gram stain
125439		93.813
125439		98.482	positive

Colony morphology

@ref	Colony color	Incubation period	Medium used
19480	Claret violet	10-14 days	ISP 2
19480	Brown red	10-14 days	ISP 3
19480	Claret violet	10-14 days	ISP 4
19480	Claret violet	10-14 days	ISP 5
19480	Beige	10-14 days	ISP 6
19480	Brown	10-14 days	ISP 7

Multicellular morphology

@ref	Complex name	Complex color	Medium name
19480	Aerial Mycelium	Grey	ISP 2
19480	Aerial Mycelium	White	ISP 3
19480	Aerial Mycelium	White	ISP 4
19480	Aerial Mycelium	Grey	ISP 5
19480	Aerial Mycelium	White	ISP 6
19480	Aerial Mycelium	Grey	ISP 7

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
9763	GYM STREPTOMYCES MEDIUM (DSMZ Medium 65)	Medium recipe at MediaDive	Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 18.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water
19480	ISP 2		Name: ISP 2 / Yeast Malt Agar (5265); 5265 Composition Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l Agar 15.0 g/l Preparation: Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.0 Usage: Maintenance and Taxonomy Organisms: All Actinomycetes
19480	ISP 3		Name: ISP 3; 5315 Composition Dog oat flakes 20.0 g/l Trace element solution (5314) 2.5 ml/l Agar 18.0 g/l Preparation: Oat flakes are cooked for 20 minutes, trace element solution and agar are added (in the case of non rolled oat flakes the suspension has to bee filtrated). Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.8 Usage: Maintenance and taxonomy (e.g. SEM As liquid medium for metabolite production) Organisms: All Actinomycetes Trace element solution 5314 Name: Trace element solution 5314; 5314 Composition CaCl2 x H2O 3.0 g/l Fe-III-citrate 1.0 g/l MnSO4 0.2 g/l ZnCl2 0.1 g/l CuSO4 x 5 H2O 0.025 g/l Sodium tetra borate 0.2 g/l CoCl2 x 6 H2O 0.004 g/l Sodium molybdate 0.01 g/l Preparation: Use double destillated water. Sterilisation: 20 minutes at 121°C pH before sterilisation: Usage: Trace element solution for different media Organisms:
19480	ISP 4		Name: ISP 4; DSM 547 Solution I: Difco soluble starch, 10.0 g. Make a paste of the starch with a small amount of cold distilled water and bring to a volume of 500 ml. Solution II: CaCO3 2.0 g K2HPO4 (anhydrous) 1.0 g MgSO4 x 7 H2O 1.0 g NaCl 1.0 g (NH4)2SO4 2.0 g Distilled water 500.0 ml Trace salt solution (see below) 1.0 ml The pH should be between 7.0 and 7.4. Do not adjust if it is within this range. Mix solutions I and II together. Add 20.0 g agar. Liquify agar by steaming at 100°C for 10 to 20 min. Trace element solution: FeSO4 x 7 H2O 0.1 g MnCl2 x 4 H2O 0.1 g ZnSO4 x 7 H2O 0.1 g Distilled water 100.0 ml
19480	ISP 5		Name: ISP 5 (5323) Composition L-Asparagine 1.0 g/l Glycerol 10.0 g/l K2HPO4 1.0 g/l Salt solution (see preparation) 1.0 ml/l Agar 20.0 g/l Preparation: Salt solution 1.0 g FeSO4 x 7 H2O 1.0 g MnCl2 x 4 H2O 1.0 g ZNSO4 x 7 H2O in 100 ml water Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.2 Usage: Maintenance and taxonomy Organisms: All Actinomycetes
19480	ISP 6		Name: ISP 6 (5318) Composition Peptone 15.0 g/l Proteose peptose 5.0 g/l Ferric ammonium citrate 0.5 g/l Sodium glycerophosphate 1.0 g/l Sodium thiosulfate 0.08 g/l Yeast extract 1.0 g/l Agar 15.0 g/l Sterilisation: 20 minutes at 121°C pH before sterilisation: Usage: Production of melanoid pigments Organisms: All Actinomycetes
19480	ISP 7		Name: ISP 7 (5322) Composition Glycerol 15.0 g/l L-Tyrosine 0.5 g/l L-Asparagine 1.0 g/l K2HPO4 0.5 g/l NaCl 0.5 g/l FeSO4 x 7 H2O 0.01 g/l Trace element solution 5343 1.0 ml/l Agar 20.0 Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.3 Usage: Production of melanoid pigments Organisms: All Actinomycetes
9763	ROLLED OATS MINERAL MEDIUM (DSMZ Medium 84)	Medium recipe at MediaDive	Name: ROLLED OATS MINERAL MEDIUM (DSMZ Medium 84) Composition: Agar 20.0 g/l Rolled oats 20.0 g/l ZnSO4 x 7 H2O 0.001 g/l MnCl2 x 4 H2O 0.001 g/l FeSO4 x 7 H2O 0.001 g/l Distilled water

Culture temp

@ref	Growth	Type	Temperature (°C)
9763	positive	growth	28
19480	positive	optimum	28
67770	positive	growth	28

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
125439	obligate aerobe	98.869

Spore formation

@ref	Spore formation	Confidence
125439		96.118
125438		90.393

Compound production

@ref	Compound
9763	moenomycin complex
19480	Moenomycin
19480	Bambermycin
19480	Flavomycin

Halophily

@ref	Salt	Growth	Tested relation	Concentration
19480	NaCl	positive	maximum	2.5 %

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
19480	22599 ChEBI	arabinose	+
68368	29016 ChEBI	arginine	-	hydrolysis	from API 20E
19480	62968 ChEBI	cellulose	+/-
68368	16947 ChEBI	citrate	+	assimilation	from API 20E
19480	28757 ChEBI	fructose	+
68368	5291 ChEBI	gelatin	+	hydrolysis	from API 20E
19480	17234 ChEBI	glucose	+
68368	25094 ChEBI	lysine	+	degradation	from API 20E
19480	29864 ChEBI	mannitol	+
19480	17268 ChEBI	myo-inositol	+
68368	18257 ChEBI	ornithine	+	degradation	from API 20E
19480	16634 ChEBI	raffinose	+/-
19480	26546 ChEBI	rhamnose	+
19480	17992 ChEBI	sucrose	+/-
68368	27897 ChEBI	tryptophan	-	energy source	from API 20E
68368	16199 ChEBI	urea	+	hydrolysis	from API 20E
19480	18222 ChEBI	xylose	+/-

Metabolite production

@ref	Chebi-ID	Metabolite
68368	15688 ChEBI	acetoin	from API 20E
67770	28908 ChEBI	bambermycin
68368	16136 ChEBI	hydrogen sulfide	from API 20E
68368	35581 ChEBI	indole	from API 20E

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test	Indole test
68368	15688 ChEBI	acetoin	+		from API 20E
68368	35581 ChEBI	indole		-	from API 20E

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
68382	alkaline phosphatase	+	3.1.3.1	from API zym
68382	alpha-chymotrypsin	+	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	+	3.2.1.22	from API zym
68382	alpha-glucosidase	+	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68368	arginine dihydrolase	-	3.5.3.6	from API 20E
68382	beta-galactosidase	+	3.2.1.23	from API zym
68368	beta-galactosidase	+	3.2.1.23	from API 20E
68382	beta-glucosidase	+	3.2.1.21	from API zym
68382	beta-glucuronidase	+	3.2.1.31	from API zym
68382	cystine arylamidase	+	3.4.11.3	from API zym
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
68368	gelatinase	+		from API 20E
68382	leucine arylamidase	+	3.4.11.1	from API zym
68382	lipase (C 14)	+		from API zym
68368	lysine decarboxylase	+	4.1.1.18	from API 20E
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
68368	ornithine decarboxylase	+	4.1.1.17	from API 20E
68382	trypsin	+	3.4.21.4	from API zym
68368	tryptophan deaminase	-	4.1.99.1	from API 20E
68368	urease	+	3.5.1.5	from API 20E
68382	valine arylamidase	+		from API zym

API 20E

@ref	ONPG	ADH (Arg)	LDC (Lys)	ODC	CIT	H2S productionH2S	URE	TDA (Trp)	IND	Acetoin production (Voges Proskauer test)VP	GEL	GLU	MAN	INO	Sor	RHA	SAC	MEL	AMY	ARA	OX	Nitrite productionNO2	Reduction to N2N2	MotilityMOB	Growth on MacConkey mediumMAC	OF-O	OF-F
19480	+	-	+	+	+	-	+	-	-	+	+	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
19480	not determinedn.d.	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	-	-	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Environmental	#Terrestrial	#Soil

Isolation

@ref	Sample type	Geographic location	Country	Country ISO 3 Code	Continent
9763	soil
67770	Soil	Bamberg	Germany	DEU	Europe

Taxonmaps

69479

Global distribution of 16S sequence AY999801 (>99% sequence identity) for Streptomyces from Microbeatlas

Aquatic Samples	41
Soil Samples	341
Animal Samples	50
Plant Samples	17
Total Samples	449

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
9763	1	Risk group (German classification) According to TRBA 466
19480	1	Risk group (German classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	NCBI tax ID	Score	IMG accession
66792	ASM870444v1 assembly for Streptomyces prasinus ATCC 13879	complete	GCA_008704445	67345.6	67345	99.36
67770	ASM141816v1 assembly for Streptomyces prasinus NRRL B-12521	scaffold	GCA_001418165		67345	0	2671180271

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Streptomyces bambergiensis gene for 16S ribosomal RNA, partial sequence, strain: JCM 4728	D44315	120	33009
20218	Streptomyces bambergiensis gene for 16S rRNA, partial sequence, strain: NBRC 13479	AB184869	1464	33009
20218	Streptomyces bambergiensis strain NRRL B-12101 16S ribosomal RNA gene, partial sequence	AY999801	1210	33009
20218	Streptomyces bambergiensis strain NRRL B-12521 16S ribosomal RNA gene, partial sequence	EF654096	1578	33009

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: ASM870444v1 assembly for Streptomyces prasinus ATCC 13879
BV-BRC: 67345.6

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	gram_stain	BacteriaNetⓘ	positive	98.48	no
125439	oxygen_tolerance	BacteriaNetⓘ	obligate aerobe	98.87	no
125439	motility	BacteriaNetⓘ	no	93.81	no
125439	spore_formation	BacteriaNetⓘ	yes	96.12	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Streptomyces prasinus ATCC 13879
NCBI: GCA_008704445.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	88.50	no
125438	anaerobic	anaerobicⓘ	no	97.06	no
125438	aerobic	aerobicⓘ	yes	89.69	no
125438	spore-forming	spore-formingⓘ	yes	90.39	no
125438	thermophilic	thermophileⓘ	no	95.00	yes
125438	flagellated	motile2+ⓘ	no	88.00	no

Literature

Topic	Title	Authors	Journal	DOI	Year
Genetics	Whole-genome sequencing-based characterization of Streptomyces sp. 6(4): focus on natural product.	Borba MP, Witusk JP, Cunha DM, de Lima-Morales D, Martins AF, Van Der Sand S.	Access Microbiol	10.1099/acmi.0.000466.v3	2023
	Engineering BioBricks for Deoxysugar Biosynthesis and Generation of New Tetracenomycins.	Tirkkonen H, Brown KV, Niemczura M, Faudemer Z, Brown C, Ponomareva LV, Helmy YA, Thorson JS, Nybo SE, Metsa-Ketela M, Shaaban KA.	ACS Omega	10.1021/acsomega.3c02460	2023
Genetics	Draft genome sequence of Streptomyces sp. Sce081 isolated from the nest of wasp Sceliphron destillatorium (Illiger, 1807).	Pytel-Huta S, Kachor A, Zatushevsky A, Samborskyy M, Rebets Y.	Microbiol Resour Announc	10.1128/mra.01125-24	2025
Phylogeny	Re-classification of Streptomyces venezuelae strains and mining secondary metabolite biosynthetic gene clusters.	Lee N, Choi M, Kim W, Hwang S, Lee Y, Kim JH, Kim G, Kim H, Cho S, Kim SC, Palsson B, Jang KS, Cho BK.	iScience	10.1016/j.isci.2021.103410	2021
	Antibacterial and Anticancer Properties of Endophenazines from Streptomyces prasinus ZO16, an Endophyte in Zingiber officinale Rosc.	Taechowisan T, Chuen-Im T, Phutdhawong WS.	Pak J Biol Sci	10.3923/pjbs.2024.469.478	2024
Genetics	Genome mining of Streptomyces bambergiensis AC-800 unravels the biosynthetic gene cluster for inhibitors of prolyl hydroxylase fibrostatins	Guerrero Garzon J, Zehl M, Schneider O, Marquez I, Ruckert-Reed C, Kalinowski J, Zotchev S.	Sci Rep		2025
Phylogeny	Taxonomic evaluation of species in the Streptomyces hirsutus clade using multi-locus sequence analysis and proposals to reclassify several species in this clade.	Labeda DP, Rong X, Huang Y, Doroghazi JR, Ju KS, Metcalf WW.	Int J Syst Evol Microbiol	10.1099/ijsem.0.001017	2016
Phylogeny	Phylogenetic relationships in the family Streptomycetaceae using multi-locus sequence analysis.	Labeda DP, Dunlap CA, Rong X, Huang Y, Doroghazi JR, Ju KS, Metcalf WW.	Antonie Van Leeuwenhoek	10.1007/s10482-016-0824-0	2017
Metabolism	Prasinons A and B: potent insecticides from Streptomyces prasinus.	Box SJ, Cole M, Yeoman GH.	Appl Microbiol	10.1128/am.26.5.699-704.1973	1973
	Biological characterization of prasinomycin, a phosphorus-containing antibiotic.	Meyers E, Miraglia GJ, Smith DA, Basch HI, Pansy FE, Trejo WH, Donovick R.	Appl Microbiol	10.1128/am.16.4.603-608.1968	1968
Phylogeny	Streptomyces chlorus sp. nov. and Streptomyces viridis sp. nov., isolated from soil.	Kim BY, Rong X, Zucchi TD, Huang Y, Goodfellow M.	Int J Syst Evol Microbiol	10.1099/ijs.0.045906-0	2013
Phylogeny	Streptomyces herbaceus sp. nov., Streptomyces incanus sp. nov. and Streptomyces pratens sp. nov., isolated from the soil of a hay meadow.	Kim BY, Rong X, Zucchi TD, Bonda ANV, Huang Y, Goodfellow M.	Int J Syst Evol Microbiol	10.1099/ijs.0.036384-0	2012
Phylogeny	Streptomyces emeiensis sp. nov., a novel streptomycete from soil in China.	Sun W, Huang Y, Zhang YQ, Liu ZH	Int J Syst Evol Microbiol	10.1099/ijs.0.64934-0	2007

References

#9763	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 40744
#19480	Wink, J.: Compendium of Actinobacteria. HZI-Helmholtz-Centre for Infection Research, Braunschweig .
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68368	Automatically annotated from API 20E .
#68382	Automatically annotated from API zym .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

Content

About us

Streptomyces prasinus (DSM 40744, ATCC 13879, CBS 780.72)

Name and taxonomic classification

Morphology

Cell morphology

Colony morphology

Multicellular morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Spore formation

Compound production

Halophily

Metabolite utilization

Metabolite production

Metabolite tests

Enzymes

API 20E

API zym

Isolation, sampling and environmental information

Isolation source categories

Isolation

Taxonmaps

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_008704445

16S sequences

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

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