Streptococcus pneumoniae (DSM 11865, 665)
Streptococcus pneumoniae 665 is a microaerophile human pathogen that was isolated from clinical source.
microaerophile human pathogen genome sequence BacteriaName and taxonomic classification
| @ref 20215 |
Last LPSN update
2026-05-29 08:28:21 |
| Domain Bacteria |
| Phylum Bacillota |
| Class Bacilli |
| Order Lactobacillales |
| Family Streptococcaceae |
| Genus Streptococcus |
| Species Streptococcus pneumoniae |
| Full scientific name Streptococcus pneumoniae (Klein 1884) Chester 1901 (Approved Lists 1980) |
| Synonyms (2) |
Culture and growth conditions
Culture medium
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 4515 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | Medium recipe at MediaDive  | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base | ||
| 4515 | TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) | Medium recipe at MediaDive | Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92; with strain-specific modifications) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Choline 1.0 g/l Distilled water |
Culture temp
| @ref | Growth | Type | Temperature (°C) | |
|---|---|---|---|---|
| 4515 | positive | growth | 37 |
Physiology and metabolism
Metabolite utilization
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68381 | 40585 ChEBI | alpha-cyclodextrin | - | builds acid from | from API rID32STR |
| 68381 | 29016 ChEBI | arginine | - | hydrolysis | from API rID32STR |
| 68381 | 18333 ChEBI | D-arabitol | - | builds acid from | from API rID32STR |
| 68381 | 16899 ChEBI | D-mannitol | - | builds acid from | from API rID32STR |
| 68381 | 16988 ChEBI | D-ribose | - | builds acid from | from API rID32STR |
| 68381 | 16443 ChEBI | D-tagatose | - | builds acid from | from API rID32STR |
| 68381 | 28087 ChEBI | glycogen | - | builds acid from | from API rID32STR |
| 68381 | 606565 ChEBI | hippurate | - | hydrolysis | from API rID32STR |
| 68381 | 30849 ChEBI | L-arabinose | - | builds acid from | from API rID32STR |
| 68381 | 17716 ChEBI | lactose | + | builds acid from | from API rID32STR |
| 68381 | 17306 ChEBI | maltose | + | builds acid from | from API rID32STR |
| 68381 | 6731 ChEBI | melezitose | - | builds acid from | from API rID32STR |
| 68381 | 28053 ChEBI | melibiose | - | builds acid from | from API rID32STR |
| 68381 | 320055 ChEBI | methyl beta-D-glucopyranoside | - | builds acid from | from API rID32STR |
| 68381 | 30911 ChEBI | sorbitol | - | builds acid from | from API rID32STR |
| 68381 | 17992 ChEBI | sucrose | + | builds acid from | from API rID32STR |
| 68381 | 27082 ChEBI | trehalose | + | builds acid from | from API rID32STR |
| 68381 | 16199 ChEBI | urea | - | hydrolysis | from API rID32STR |
Metabolite production
| @ref | Chebi-ID | Metabolite | Production | |
|---|---|---|---|---|
| 68381 | 15688 ChEBI | acetoin | from API rID32STR |
Metabolite tests
| @ref | Chebi-ID | Metabolite | Voges-proskauer-test | |
|---|---|---|---|---|
| 68381 | 15688 ChEBI | acetoin | - | from API rID32STR |
Enzymes
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68381 | Alanyl-Phenylalanyl-Proline arylamidase | + | from API rID32STR | |
| 68381 | alkaline phosphatase | - | 3.1.3.1 | from API rID32STR |
| 68381 | arginine dihydrolase | - | 3.5.3.6 | from API rID32STR |
| 68381 | beta-galactosidase | - | 3.2.1.23 | from API rID32STR |
| 68381 | beta-glucosidase | - | 3.2.1.21 | from API rID32STR |
| 68381 | beta-glucuronidase | - | 3.2.1.31 | from API rID32STR |
| 68381 | beta-mannosidase | - | 3.2.1.25 | from API rID32STR |
| 68381 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API rID32STR |
| 68381 | pyrrolidonyl arylamidase | - | 3.4.19.3 | from API rID32STR |
| 68381 | urease | - | 3.5.1.5 | from API rID32STR |
API rID32STR
| @ref | ADH (Arg) | beta GLU | beta GAR | beta GUR | alpha GAL | PAL | RIB | MAN | SOR | LAC | TRE | RAF | SAC | LARA | DARL | Acid from alpha-cyclodextrinCDEX | Acetoin production (Voges Proskauer test)VP | Alanyl-Phenylalanyl-Proline arylamidaseAPPA | beta GAL | Pyrrolidonyl arylamidasePyrA | N-Acetyl-glucosaminidasebeta NAG | Glycyl-tryptophan arylamidaseGTA | HIP | GLYG | PUL | MAL | MEL | MLZ | Acidification of methyl beta-D-glucopyranosideMbeta DG | TAG | beta MAN | URE | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 4515 | - | - | + | - | - | - | - | - | - | + | + | +/- | + | - | - | - | - | + | - | - | - | - | - | - | - | + | - | - | - | - | - | - | |
| 4515 | - | - | + | - | + | - | - | - | - | + | + | + | + | - | - | - | - | + | - | - | - | + | - | - | + | + | - | - | - | - | - | - |
Sequence information
Genome sequences
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|
| 66792 | Streptococcus pneumoniae strain FDAARGOS_1508 | complete | 1313.39238  | 1313 | 99.8 | | |
| 66792 | Streptococcus pneumoniae strain FDAARGOS_1508 | complete | 1313.38496 | 1313 | 99.8 | | |
| 66792 | Streptococcus pneumoniae strain FDAARGOS_1508 | complete | 1313.39166 | 1313 | 99.8 | | |
| 124043 | ASM2009733v1 assembly for Streptococcus pneumoniae FDAARGOS_1508 | complete | GCA_020097335  | 1313.38070 | 1313 | 99.06 | |
Genome browser: GCA_020097335
Literature
Literature 
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Synthetic studies on the tetrasubstituted D-ring of cystobactamids lead to potent terephthalic acid antibiotics. | Stappert M, Kohnhauser D, Seedorf T, Coetzee J, Rox K, Fuchs HLS, Cirnski K, Leitner C, Herrmann J, Kirschning A, Muller R, Bronstrup M. | Commun Chem | 10.1038/s42004-024-01337-6 | 2024 | | |
| An Efficient Way to Screen Inhibitors of Energy-Coupling Factor (ECF) Transporters in a Bacterial Uptake Assay. | Bousis S, Winkler S, Haupenthal J, Fulco F, Diamanti E, Hirsch AKH. | Int J Mol Sci | 10.3390/ijms23052637 | 2022 | | |
| A New Phage Lysin Isolated from the Oral Microbiome Targeting Streptococcus pneumoniae. | van der Kamp I, Draper LA, Smith MK, Buttimer C, Ross RP, Hill C. | Pharmaceuticals (Basel) | 10.3390/ph13120478 | 2020 | | |
| Recombinant of the Staphylococcal Bacteriophage Lysin CHAPk and Its Elimination against Streptococcus agalactiae Biofilms. | Shan Y, Yang N, Teng D, Wang X, Mao R, Hao Y, Ma X, Fan H, Wang J. | Microorganisms | 10.3390/microorganisms8020216 | 2020 | | |
| Metabolism | Development of a rapid recombinase polymerase amplification assay for the detection of Streptococcus pneumoniae in whole blood. | Clancy E, Higgins O, Forrest MS, Boo TW, Cormican M, Barry T, Piepenburg O, Smith TJ. | BMC Infect Dis | 10.1186/s12879-015-1212-5 | 2015 | |
| Metabolism | Lipodepsipeptide empedopeptin inhibits cell wall biosynthesis through Ca2+-dependent complex formation with peptidoglycan precursors. | Muller A, Munch D, Schmidt Y, Reder-Christ K, Schiffer G, Bendas G, Gross H, Sahl HG, Schneider T, Brotz-Oesterhelt H. | J Biol Chem | 10.1074/jbc.m112.369561 | 2012 | |
| Metabolism | Effects of Halide Ions on the Carbamidocyclophane Biosynthesis in Nostoc sp. CAVN2. | Preisitsch M, Heiden SE, Beerbaum M, Niedermeyer TH, Schneefeld M, Herrmann J, Kumpfmuller J, Thurmer A, Neidhardt I, Wiesner C, Daniel R, Muller R, Bange FC, Schmieder P, Schweder T, Mundt S. | Mar Drugs | 10.3390/md14010021 | 2016 | |
| Antibody to a conserved antigenic target is protective against diverse prokaryotic and eukaryotic pathogens. | Cywes-Bentley C, Skurnik D, Zaidi T, Roux D, Deoliveira RB, Garrett WS, Lu X, O'Malley J, Kinzel K, Zaidi T, Rey A, Perrin C, Fichorova RN, Kayatani AK, Maira-Litran T, Gening ML, Tsvetkov YE, Nifantiev NE, Bakaletz LO, Pelton SI, Golenbock DT, Pier GB. | Proc Natl Acad Sci U S A | 10.1073/pnas.1303573110 | 2013 | | |
| Enzymology | Evaluation of a novel real-time PCR test based on the ssrA gene for the identification of group B streptococci in vaginal swabs. | Wernecke M, Mullen C, Sharma V, Morrison J, Barry T, Maher M, Smith T. | BMC Infect Dis | 10.1186/1471-2334-9-148 | 2009 | |
How to cite
If you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive14742.20260601.11
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain dataIsabel Schober, Julia Koblitz, Joaquim Sardà Carbasse, Christian Ebeling, Marvin Leon Schmidt, Adam Podstawka, Rohit Gupta, Vinodh Ilangovan, Javad Chamanara, Jörg Overmann, Lorenz Christian Reimer
Nucleic Acids Research; database issue 2025.
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