Clostridioides difficile CCUG 20309 is an anaerobe, mesophilic prokaryote that was isolated from Human clinical specimen.
anaerobe mesophilic| @ref 20215 |
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| Domain Bacteria |
| Phylum Bacillota |
| Class Clostridia |
| Order Peptostreptococcales |
| Family Peptostreptococcaceae |
| Genus Clostridioides |
| Species Clostridioides difficile |
| Full scientific name Clostridioides difficile (Hall and O'Toole 1935) Lawson et al. 2016 |
| Synonyms (3) |
| @ref | Growth | Type | Temperature (°C) | Range | |
|---|---|---|---|---|---|
| 47126 | positive | growth | 37 | mesophilic |
| 47126 | Oxygen toleranceanaerobe |
| Cat1 | Cat2 | Cat3 | |
|---|---|---|---|
| #Host | #Human | - | |
| #Infection | #Patient | - | |
| #Infection | #Medical environment | #Clinic | |
| #Infection | #Patient | #Specimen |
| @ref | Sample type | Geographic location | Country | Country ISO 3 Code | Continent | |
|---|---|---|---|---|---|---|
| 47126 | Human clinical specimen | Birmingham,The General Hospital | United Kingdom | GBR | Europe |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| ADP-ribosylating binary toxin genes of Clostridium difficile strain CCUG 20309. | Chang SY, Song KP. | DNA Seq | 10.3109/10425170109047564 | 2001 | ||
| Metabolism | Development of TaqMan-based quantitative PCR for sensitive and selective detection of toxigenic Clostridium difficile in human stools. | Kubota H, Sakai T, Gawad A, Makino H, Akiyama T, Ishikawa E, Oishi K. | PLoS One | 10.1371/journal.pone.0111684 | 2014 | |
| Clonal spread of a Clostridium difficile strain with a complete set of toxin A, toxin B, and binary toxin genes among Polish patients with Clostridium difficile-associated diarrhea. | Pituch H, Kreft D, Obuch-Woszczatynski P, Wultanska D, Meisel-Mikolajczyk F, Luczak M, van Belkum A. | J Clin Microbiol | 10.1128/jcm.43.1.472-475.2005 | 2005 | ||
| Phylogeny | Increased sporulation rate of epidemic Clostridium difficile Type 027/NAP1. | Akerlund T, Persson I, Unemo M, Noren T, Svenungsson B, Wullt M, Burman LG. | J Clin Microbiol | 10.1128/jcm.01964-07 | 2008 | |
| Metabolism | Toxin profiles and resistances to macrolides and newer fluoroquinolones as epidemicity determinants of clinical isolates of Clostridium difficile from Warsaw, Poland. | Pituch H, van Leeuwen W, Maquelin K, Wultanska D, Obuch-Woszczatynski P, Nurzynska G, Kato H, Reijans M, Meisel-Mikolajczyk F, Luczak M, van Belkum A. | J Clin Microbiol | 10.1128/jcm.00306-07 | 2007 | |
| Pathogenicity | Recombinant antigens based on toxins A and B of Clostridium difficile that evoke a potent toxin-neutralising immune response. | Maynard-Smith M, Ahern H, McGlashan J, Nugent P, Ling R, Denton H, Coxon R, Landon J, Roberts A, Shone C. | Vaccine | 10.1016/j.vaccine.2013.11.099 | 2014 | |
| Enzymology | Automated detection of toxigenic Clostridium difficile in clinical samples: isothermal tcdB amplification coupled to array-based detection. | Hicke B, Pasko C, Groves B, Ager E, Corpuz M, Frech G, Munns D, Smith W, Warcup A, Denys G, Ledeboer NA, Lindsey W, Owen C, Rea L, Jenison R. | J Clin Microbiol | 10.1128/jcm.00621-12 | 2012 | |
| Phylogeny | International typing study of toxin A-negative, toxin B-positive Clostridium difficile variants. | Johnson S, Sambol SP, Brazier JS, Delmee M, Avesani V, Merrigan MM, Gerding DN. | J Clin Microbiol | 10.1128/jcm.41.4.1543-1547.2003 | 2003 | |
| Binary toxin production in Clostridium difficile is regulated by CdtR, a LytTR family response regulator. | Carter GP, Lyras D, Allen DL, Mackin KE, Howarth PM, O'Connor JR, Rood JI. | J Bacteriol | 10.1128/jb.00731-07 | 2007 | ||
| Metabolism | Toxins, butyric acid, and other short-chain fatty acids are coordinately expressed and down-regulated by cysteine in Clostridium difficile. | Karlsson S, Lindberg A, Norin E, Burman LG, Akerlund T. | Infect Immun | 10.1128/iai.68.10.5881-5888.2000 | 2000 | |
| Characterization of a toxin A-negative, toxin B-positive strain of Clostridium difficile. | Lyerly DM, Barroso LA, Wilkins TD, Depitre C, Corthier G. | Infect Immun | 10.1128/iai.60.11.4633-4639.1992 | 1992 | ||
| Pathogenicity | Nucleotide and peptide sequences of the open reading frame encoding a truncated toxin A gene of Clostridium difficile strain CCUG 20309. | Song KP, Bai XL, Chang SY | DNA Seq | 10.3109/10425179909008423 | 1999 | |
| Pathogenicity | A Protein Microarray Assay for Serological Determination of Antigen-specific Antibody Responses Following Clostridium difficile Infection. | Negm OH, Hamed M, Monaghan TM | J Vis Exp | 10.3791/57399 | 2018 | |
| High prevalence of subclass-specific binding and neutralizing antibodies against Clostridium difficile toxins in adult cystic fibrosis sera: possible mode of immunoprotection against symptomatic C. difficile infection. | Monaghan TM, Negm OH, MacKenzie B, Hamed MR, Shone CC, Humphreys DP, Acharya KR, Wilcox MH | Clin Exp Gastroenterol | 10.2147/CEG.S133939 | 2017 |
| #20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 ) |
| #47126 | Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 20309 |
| #126262 | A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 ) |
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