Haemophilus influenzae 595 is a mesophilic, oval-shaped prokaryote of the family Pasteurellaceae.
oval-shaped mesophilic 16S sequence| @ref 20215 |
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| Domain Bacteria |
| Phylum Pseudomonadota |
| Class Gammaproteobacteria |
| Order Pasteurellales |
| Family Pasteurellaceae |
| Genus Haemophilus |
| Species Haemophilus influenzae |
| Full scientific name Haemophilus influenzae corrig. (Lehmann and Neumann 1896) Winslow et al. 1917 (Approved Lists 1980) |
| Synonyms (2) |
| 41449 | Cell shapeoval-shaped |
| @ref | Name | Growth | Composition | Medium link | |
|---|---|---|---|---|---|
| 41449 | MEDIUM 10 - Chocolate medium for Actinobacillus pleuropneumoniae, Capnocytophaga cynodegmi, Haemophilus and Neisseria | Distilled water make up to (1000.000 ml);Columbia agar (39.000 g);Horseblood (100.000 ml);PolyVitex mischung (10.000 ml) | |||
| 41449 | CIP Medium 10 | Medium recipe at CIP |
| @ref | Growth | Type | Temperature (°C) | Range | |
|---|---|---|---|---|---|
| 41449 | positive | growth | 37 | mesophilic |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68382 | acid phosphatase | + | 3.1.3.2 | from API zym |
| 41449 | alcohol dehydrogenase | - | 1.1.1.1 | |
| 68382 | alkaline phosphatase | + | 3.1.3.1 | from API zym |
| 68382 | alpha-chymotrypsin | - | 3.4.21.1 | from API zym |
| 68382 | alpha-fucosidase | - | 3.2.1.51 | from API zym |
| 68382 | alpha-galactosidase | - | 3.2.1.22 | from API zym |
| 68382 | alpha-glucosidase | - | 3.2.1.20 | from API zym |
| 68382 | alpha-mannosidase | - | 3.2.1.24 | from API zym |
| 68382 | beta-galactosidase | - | 3.2.1.23 | from API zym |
| 41449 | beta-galactosidase | - | 3.2.1.23 | |
| 68382 | beta-glucosidase | - | 3.2.1.21 | from API zym |
| 68382 | beta-glucuronidase | - | 3.2.1.31 | from API zym |
| 41449 | catalase | + | 1.11.1.6 | |
| 68382 | cystine arylamidase | - | 3.4.11.3 | from API zym |
| 68382 | esterase (C 4) | - | from API zym | |
| 68382 | esterase lipase (C 8) | - | from API zym | |
| 68382 | leucine arylamidase | + | 3.4.11.1 | from API zym |
| 68382 | lipase (C 14) | - | from API zym | |
| 41449 | lysine decarboxylase | - | 4.1.1.18 | |
| 68382 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API zym |
| 68382 | naphthol-AS-BI-phosphohydrolase | + | from API zym | |
| 41449 | ornithine decarboxylase | + | 4.1.1.17 | |
| 68382 | trypsin | - | 3.4.21.4 | from API zym |
| 41449 | urease | + | 3.5.1.5 | |
| 68382 | valine arylamidase | - | from API zym |
| @ref | Biosafety level | Biosafety level comment | |
|---|---|---|---|
| 41449 | 2 | Risk group (French classification) |
| @ref | Description | Accession | Length | Database | NCBI tax ID | |
|---|---|---|---|---|---|---|
| 124043 | Haemophilus influenzae ATCC 8142 16S ribosomal RNA gene, partial sequence. | AF224305 | 1516 | 123832 |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Characteristics and antimicrobial susceptibility of bacteria causing acute otitis media in children at Vietnam National Children's Hospital: a cross-sectional study. | Do HD, Tran MD, Nguyen TX, Thuy Phung TB, Ngoc Hoang TB, Lien Pham TL, Nguyen M, DeAngelis E, Than HT, Nguyen KT, Guzman-Holst A. | JAC Antimicrob Resist | 10.1093/jacamr/dlaf006 | 2025 | ||
| Impact of a Single-Tube PCR Assay for the Detection of Haemophilus influenzae Serotypes a, c, d, e and f on the Epidemiological Surveillance in Greece. | Xirogianni A, Georgakopoulou T, Patsourakos V, Magaziotou I, Papandreou A, Simantirakis S, Tzanakaki G. | Microorganisms | 10.3390/microorganisms10071367 | 2022 | ||
| Epidemiological analysis and rapid detection by one-step multiplex PCR assay of Haemophilus influenzae in children with respiratory tract infections in Zhejiang Province, China. | Fan X, Liu X, Ji L, Cai D, Jiang J, Zhu J, Sun A, Yan J. | BMC Infect Dis | 10.1186/s12879-018-3295-2 | 2018 | ||
| Enzymology | Duplex Quantitative PCR Assay for Detection of Haemophilus influenzae That Distinguishes Fucose- and Protein D-Negative Strains. | de Gier C, Pickering JL, Richmond PC, Thornton RB, Kirkham LA. | J Clin Microbiol | 10.1128/jcm.00982-16 | 2016 | |
| Phylogeny | Clinical and Bacteriologic Analysis of Nontypeable Haemophilus influenzae Strains Isolated from Children with Invasive Diseases in Japan from 2008 to 2015. | Naito S, Takeuchi N, Ohkusu M, Takahashi-Nakaguchi A, Takahashi H, Imuta N, Nishi J, Shibayama K, Matsuoka M, Sasaki Y, Ishiwada N. | J Clin Microbiol | 10.1128/jcm.00141-18 | 2018 | |
| Enzymology | Comparison of PCR-based methods for the simultaneous detection of Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae in clinical samples. | de Filippis I, de Andrade CF, Caldeira N, de Azevedo AC, de Almeida AE. | Braz J Infect Dis | 10.1016/j.bjid.2016.04.005 | 2016 | |
| Enzymology | Bacteremia and malaria in Tanzanian children hospitalized for acute febrile illness. | Lundgren IS, Heltshe SL, Smith AL, Chibwana J, Fried MW, Duffy PE. | J Trop Pediatr | 10.1093/tropej/fmu069 | 2015 | |
| Determination of capsulation status in Haemophilus influenzae by multiplex polymerase chain reaction. | Nelson KL, Smith AL. | Diagn Microbiol Infect Dis | 10.1016/j.diagmicrobio.2009.10.005 | 2010 | ||
| Enzymology | Detection of Haemophilus influenzae type b by real-time PCR. | Marty A, Greiner O, Day PJ, Gunziger S, Muhlemann K, Nadal D. | J Clin Microbiol | 10.1128/jcm.42.8.3813-3815.2004 | 2004 | |
| Phylogeny | Real-time PCR for determining capsular serotypes of Haemophilus influenzae. | Maaroufi Y, De Bruyne JM, Heymans C, Crokaert F. | J Clin Microbiol | 10.1128/jcm.00102-07 | 2007 | |
| Metabolism | Adhesin genes and serum resistance in Haemophilus influenzae type f isolates. | Watson ME, Nelson KL, Nguyen V, Burnham CD, Clarridge JE, Qin X, Smith AL. | J Med Microbiol | 10.1099/jmm.0.052175-0 | 2013 | |
| Chemically defined media for growth of Haemophilus influenzae strains. | Coleman HN, Daines DA, Jarisch J, Smith AL. | J Clin Microbiol | 10.1128/jcm.41.9.4408-4410.2003 | 2003 | ||
| Complete sequence of the cap locus of Haemophilus influenzae serotype b and nonencapsulated b capsule-negative variants. | Satola SW, Schirmer PL, Farley MM. | Infect Immun | 10.1128/iai.71.6.3639-3644.2003 | 2003 | ||
| Development of a Diagnostic Kit to Detect Cryptosporidium parvum and Giardia lamblia. | Cheun HI, Chung BS, Ma DW, Goo BL, Cho SH, Ji MJ, Lee WJ. | Osong Public Health Res Perspect | 10.1016/j.phrp.2013.04.006 | 2013 | ||
| Enzymology | Development of a novel DNA microarray to detect bacterial pathogens in patients with chronic obstructive pulmonary disease (COPD). | Curran T, Coulter WA, Fairley DJ, McManus T, Kidney J, Larkin M, Moore JE, Coyle PV. | J Microbiol Methods | 10.1016/j.mimet.2010.01.004 | 2010 | |
| Phylogeny | Genetic analysis of the capsule locus of Haemophilus influenzae serotype f. | Satola SW, Schirmer PL, Farley MM. | Infect Immun | 10.1128/iai.71.12.7202-7207.2003 | 2003 | |
| Phylogeny | High level of sequence diversity in the 16S rRNA genes of Haemophilus influenzae isolates is useful for molecular subtyping. | Sacchi CT, Alber D, Dull P, Mothershed EA, Whitney AM, Barnett GA, Popovic T, Mayer LW. | J Clin Microbiol | 10.1128/jcm.43.8.3734-3742.2005 | 2005 | |
| Metabolism | Haemophilus influenzae phasevarions have evolved from type III DNA restriction systems into epigenetic regulators of gene expression. | Fox KL, Dowideit SJ, Erwin AL, Srikhanta YN, Smith AL, Jennings MP. | Nucleic Acids Res | 10.1093/nar/gkm571 | 2007 | |
| Phylogeny | Evaluation of methodology for serotyping invasive and nasopharyngeal isolates of Haemophilus influenzae in the ongoing surveillance in Brazil. | Bokermann S, Zanella RC, Lemos AP, de Andrade AL, Brandileone MC. | J Clin Microbiol | 10.1128/jcm.41.12.5546-5550.2003 | 2003 | |
| Identification and characterization of a nontypeable Haemophilus influenzae putative toxin-antitoxin locus. | Daines DA, Jarisch J, Smith AL. | BMC Microbiol | 10.1186/1471-2180-4-30 | 2004 | ||
| Enzymology | Identification and characterization of a serotype b-specific segment of the Haemophilus influenzae genome. | Ely S, Tippett J, Moxon ER. | Infect Immun | 10.1128/iai.57.9.2926-2928.1989 | 1989 | |
| Genetic characterization of a cryptic genospecies of Haemophilus causing urogenital and neonatal infections. | Quentin R, Martin C, Musser JM, Pasquier-Picard N, Goudeau A. | J Clin Microbiol | 10.1128/jcm.31.5.1111-1116.1993 | 1993 | ||
| Evolution of the major pilus gene cluster of Haemophilus influenzae. | Mhlanga-Mutangadura T, Morlin G, Smith AL, Eisenstark A, Golomb M. | J Bacteriol | 10.1128/jb.180.17.4693-4703.1998 | 1998 | ||
| Evolution of an autotransporter: domain shuffling and lateral transfer from pathogenic Haemophilus to Neisseria. | Davis J, Smith AL, Hughes WR, Golomb M. | J Bacteriol | 10.1128/jb.183.15.000-000.2001 | 2001 | ||
| Serum resistance in an invasive, nontypeable Haemophilus influenzae strain. | Williams BJ, Morlin G, Valentine N, Smith AL. | Infect Immun | 10.1128/iai.69.2.695-705.2001 | 2001 | ||
| The tryptophanase gene cluster of Haemophilus influenzae type b: evidence for horizontal gene transfer. | Martin K, Morlin G, Smith A, Nordyke A, Eisenstark A, Golomb M. | J Bacteriol | 10.1128/jb.180.1.107-118.1998 | 1998 | ||
| Contribution of a 28-kilodalton membrane protein to the virulence of Haemophilus influenzae. | Chanyangam M, Smith AL, Moseley SL, Kuehn M, Jenny P. | Infect Immun | 10.1128/iai.59.2.600-608.1991 | 1991 | ||
| Phylogeny | Genetic identification of cryptic genospecies of Haemophilus causing urogenital and neonatal infections by PCR using specific primers targeting genes coding for 16S rRNA. | Quentin R, Ruimy R, Rosenau A, Musser JM, Christen R. | J Clin Microbiol | 10.1128/jcm.34.6.1380-1385.1996 | 1996 | |
| Bacteriophage HP2 of Haemophilus influenzae. | Williams BJ, Golomb M, Phillips T, Brownlee J, Olson MV, Smith AL. | J Bacteriol | 10.1128/jb.184.24.6893-6905.2002 | 2002 | ||
| Enzymology | Cloning of chromosomal DNA from Haemophilus influenzae. Its use for studying the expression of type b capsule and virulence. | Moxon ER, Deich RA, Connelly C. | J Clin Invest | 10.1172/jci111214 | 1984 | |
| Metabolism | Haemophilus influenzae penicillin-binding proteins 1a and 3 possess distinct and opposite temperature-modulated penicillin-binding activities. | Malouin F, Bryan LE. | Antimicrob Agents Chemother | 10.1128/aac.32.4.498 | 1988 | |
| Physical and genetic analysis of DNA regions encoding the immunoglobulin A proteases of different specificities produced by Haemophilus influenzae. | Bricker J, Mulks M, Moxon ER, Plaut AG, Wright A. | Infect Immun | 10.1128/iai.47.2.370-374.1985 | 1985 | ||
| Phylogeny | Serology of oral Actinobacillus actinomycetemcomitans and serotype distribution in human periodontal disease. | Zambon JJ, Slots J, Genco RJ. | Infect Immun | 10.1128/iai.41.1.19-27.1983 | 1983 | |
| Enzymology | DNA probe technology for rapid detection of Haemophilus influenzae in clinical specimens. | Malouin F, Bryan LE, Shewciw P, Douglas J, Li D, Van den Elzen H, Lapointe JR. | J Clin Microbiol | 10.1128/jcm.26.10.2132-2138.1988 | 1988 | |
| Cultivation | Selective culture medium to survey the incidence of Haemophilus species. | Crawford JJ, Barden L, Kirkman JB. | Appl Microbiol | 10.1128/am.18.4.646-649.1969 | 1969 | |
| Metabolism | Ability of oral bacteria to degrade fibronectin. | Wikstrom M, Linde A. | Infect Immun | 10.1128/iai.51.2.707-711.1986 | 1986 | |
| Enzymology | Selective medium for the isolation of Haemophilus aphrophilus from the human periodontium and other oral sites and the low proportion of the organism in the oral flora. | Tempro PJ, Slots J. | J Clin Microbiol | 10.1128/jcm.23.4.777-782.1986 | 1986 | |
| Limited diversity of the immunoglobulin A1 protease gene (iga) among Haemophilus influenzae serotype b strains. | Poulsen K, Hjorth JP, Kilian M. | Infect Immun | 10.1128/iai.56.4.987-992.1988 | 1988 | ||
| Phylogeny | Application of multilocus enzyme gel electrophoresis to Haemophilus influenzae. | Porras O, Caugant DA, Lagergard T, Svanborg-Eden C. | Infect Immun | 10.1128/iai.53.1.71-78.1986 | 1986 | |
| Phylogeny | Difference in structure between type b and nontypable Haemophilus influenzae populations. | Porras O, Caugant DA, Gray B, Lagergard T, Levin BR, Svanborg-Eden C. | Infect Immun | 10.1128/iai.53.1.79-89.1986 | 1986 | |
| Enzyme-linked immunosorbent assay for titration of Haemophilus influenzae capsular and O antigen antibodies. | Dahlberg T, Branefors P. | J Clin Microbiol | 10.1128/jcm.12.2.185-192.1980 | 1980 | ||
| Phylogeny | Identification of Haemophilus influenzae Type b Isolates by Use of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry. | Mansson V, Resman F, Kostrzewa M, Nilson B, Riesbeck K. | J Clin Microbiol | 10.1128/jcm.00137-15 | 2015 | |
| Pathogenicity | A screening for antimicrobial activities of Caribbean herbal remedies. | Luciano-Montalvo C, Boulogne I, Gavillan-Suarez J | BMC Complement Altern Med | 10.1186/1472-6882-13-126 | 2013 | |
| Phylogeny | New diagnostic PCR for Haemophilus influenzae serotype e based on the cap locus of strain ATCC 8142. | Lam TT, Elias J, Frosch M, Vogel U, Claus H | Int J Med Microbiol | 10.1016/j.ijmm.2010.07.004 | 2011 | |
| Phylogeny | Structural studies of two capsular polysaccharides elaborated by different strains of Haemophilus influenzae type e. | Branefors-Helander P | Carbohydr Res | 10.1016/s0008-6215(00)84602-9 | 1981 |
| #20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 ) |
| #41449 | Collection of Institut Pasteur ; Curators of the CIP; CIP 54.84 |
| #44935 | Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 6877 |
| #68382 | Automatically annotated from API zym . |
| #124043 | Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy . |
| #126262 | A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 ) |
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