Facklamia ignava (CCM 4932, CIP 105583, CCUG 37419)

Name: Facklamia ignava (CCM 4932, CIP 105583, CCUG 37419)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 137693

Type strain

Strain Designation 164/97

Culture col. no. CCM 4932 CIP 105583 CCUG 37419 ATCC 700631 164/97

NCBI tax ID(s) 883112 137730

Special Collections CCUG CIP

History CIP <- 1998, CCUG <- 1997, M.D. Collins, IFR, Reading, UK: strain 164/97 <- R.R. Facklam, CDC, Atlanta, Georgia, USA <- M. Lovgren, Edmonton, Alberta, Canada

Links

Facklamia ignava 164/97 is a facultative anaerobe, Gram-positive, coccus-shaped bacterium of the family Aerococcaceae.

Gram-positive coccus-shaped facultative anaerobe genome sequence Bacteria

Name and taxonomic classification

SI-ID 12945

LMG 18981,CCUG 37419,CIP 105583,ATCC 700631,CCM 4932

@ref 20215

Last LPSN update 2026-05-29 08:39:05

Domain Bacteria

Phylum Bacillota

Class Bacilli

Order Lactobacillales

Family Aerococcaceae

Genus Facklamia

Species Facklamia ignava

Full scientific name Facklamia ignava Collins et al. 1998

Synonyms (1)

Falseniella ignava

BacDive ID	Other strains from **Facklamia ignava** (3)	Type strain
136524	F. ignava CIP 106447, CCUG 37659
151316	F. ignava CCUG 43733
154522	F. ignava CCUG 54213

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Motility	Confidence
38565	positive	coccus-shaped
125438				92

Colony morphology

38565

Hemolysis ability1

Culture and growth conditions

Culture medium

@ref	Name	Growth	Composition	Medium link
38565	MEDIUM 6 - Columbia agar with 10 % horse blood		Distilled water make up to (1000.000 ml);Columbia agar (39.000 g);Horseblood (100.000 ml)
38565	CIP Medium 6			Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)
38565	positive	growth	37
38565	positive	growth	25-41
38565	negative	growth	10
38565	negative	growth	45

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
38565	facultative anaerobe
125439	facultative anaerobe	94.787

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
38565	4853 ChEBI	esculin	-	hydrolysis
38565	606565 ChEBI	hippurate	+	hydrolysis
38565	17632 ChEBI	nitrate	-	reduction
38565	16301 ChEBI	nitrite	-	reduction

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test
38565	15688 ChEBI	acetoin	-

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	-	3.1.3.2	from API zym
38565	alcohol dehydrogenase	-	1.1.1.1
68382	alkaline phosphatase	-	3.1.3.1	from API zym
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68382	alpha-glucosidase	+	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68382	beta-galactosidase	-	3.2.1.23	from API zym
38565	beta-galactosidase	+	3.2.1.23
68382	beta-glucosidase	-	3.2.1.21	from API zym
68382	beta-glucuronidase	-	3.2.1.31	from API zym
38565	catalase	-	1.11.1.6
68382	cystine arylamidase	-	3.4.11.3	from API zym
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
38565	gamma-glutamyltransferase	-	2.3.2.2
68382	leucine arylamidase	+	3.4.11.1	from API zym
68382	lipase (C 14)	-		from API zym
38565	lysine decarboxylase	-	4.1.1.18
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
38565	ornithine decarboxylase	-	4.1.1.17
38565	oxidase	-
68382	trypsin	-	3.4.21.4	from API zym
68382	valine arylamidase	-		from API zym

Pathway annotation

Computationally determined by

@ref	pathway	enzyme coverage	annotated reactions
66794	folate polyglutamylation	100	1 of 1
66794	CDP-diacylglycerol biosynthesis	100	2 of 2
66794	ribulose monophosphate pathway	100	2 of 2
66794	peptidoglycan biosynthesis	80	12 of 15
66794	glycogen metabolism	80	4 of 5
66794	photosynthesis	78.57	11 of 14
66794	palmitate biosynthesis	77.27	17 of 22
66794	sulfopterin metabolism	75	3 of 4
66794	glycogen biosynthesis	75	3 of 4
66794	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	75	6 of 8
66794	ppGpp biosynthesis	75	3 of 4
66794	C4 and CAM-carbon fixation	75	6 of 8
66794	pentose phosphate pathway	72.73	8 of 11
66794	pyrimidine metabolism	71.11	32 of 45
66794	purine metabolism	69.15	65 of 94
66794	selenocysteine biosynthesis	66.67	4 of 6
66794	octane oxidation	66.67	2 of 3
66794	acetoin degradation	66.67	2 of 3
66794	UDP-GlcNAc biosynthesis	66.67	2 of 3
66794	L-lactaldehyde degradation	66.67	2 of 3
66794	aspartate and asparagine metabolism	66.67	6 of 9
66794	serine metabolism	66.67	6 of 9
66794	glycolysis	64.71	11 of 17
66794	gluconeogenesis	62.5	5 of 8
66794	degradation of sugar alcohols	62.5	10 of 16
66794	phenylalanine metabolism	61.54	8 of 13
66794	NAD metabolism	61.11	11 of 18
66794	metabolism of amino sugars and derivatives	60	3 of 5
66794	methylglyoxal degradation	60	3 of 5
66794	lipoate biosynthesis	60	3 of 5
66794	oxidative phosphorylation	57.14	52 of 91
66794	d-mannose degradation	55.56	5 of 9
66794	vitamin B1 metabolism	53.85	7 of 13
66794	methionine metabolism	53.85	14 of 26
66794	non-pathway related	52.63	20 of 38
66794	acetate fermentation	50	2 of 4
66794	butanoate fermentation	50	2 of 4
66794	cis-vaccenate biosynthesis	50	1 of 2
66794	Entner Doudoroff pathway	50	5 of 10
66794	ethanol fermentation	50	1 of 2
66794	starch degradation	50	5 of 10
66794	phenylmercury acetate degradation	50	1 of 2
66794	tetrahydrofolate metabolism	50	7 of 14
66794	adipate degradation	50	1 of 2
66794	mevalonate metabolism	42.86	3 of 7
66794	ubiquinone biosynthesis	42.86	3 of 7
66794	cardiolipin biosynthesis	42.86	3 of 7
66794	propanol degradation	42.86	3 of 7
66794	glutathione metabolism	42.86	6 of 14
66794	degradation of aromatic, nitrogen containing compounds	41.67	5 of 12
66794	glycine metabolism	40	4 of 10
66794	gallate degradation	40	2 of 5
66794	threonine metabolism	40	4 of 10
66794	glutamate and glutamine metabolism	39.29	11 of 28
66794	degradation of pentoses	39.29	11 of 28
66794	ketogluconate metabolism	37.5	3 of 8
66794	metabolism of disaccharids	36.36	4 of 11
66794	d-xylose degradation	36.36	4 of 11
66794	vitamin B6 metabolism	36.36	4 of 11
66794	lipid metabolism	35.48	11 of 31
66794	alanine metabolism	34.48	10 of 29
66794	histidine metabolism	34.48	10 of 29
66794	tryptophan metabolism	34.21	13 of 38
66794	IAA biosynthesis	33.33	1 of 3
66794	CO2 fixation in Crenarchaeota	33.33	3 of 9
66794	degradation of hexoses	33.33	6 of 18
66794	chorismate metabolism	33.33	3 of 9
66794	flavin biosynthesis	33.33	5 of 15
66794	glycolate and glyoxylate degradation	33.33	2 of 6
66794	cysteine metabolism	33.33	6 of 18
66794	lipid A biosynthesis	33.33	3 of 9
66794	valine metabolism	33.33	3 of 9
66794	acetyl CoA biosynthesis	33.33	1 of 3
66794	cyanate degradation	33.33	1 of 3
66794	formaldehyde oxidation	33.33	1 of 3
66794	sphingosine metabolism	33.33	2 of 6
66794	leucine metabolism	30.77	4 of 13
66794	phenylpropanoid biosynthesis	30.77	4 of 13
66794	myo-inositol biosynthesis	30	3 of 10
66794	tyrosine metabolism	28.57	4 of 14
66794	reductive acetyl coenzyme A pathway	28.57	2 of 7
66794	citric acid cycle	28.57	4 of 14
66794	biotin biosynthesis	25	1 of 4
66794	lactate fermentation	25	1 of 4
66794	cyclohexanol degradation	25	1 of 4
66794	arginine metabolism	25	6 of 24
66794	carnitine metabolism	25	2 of 8
66794	CMP-KDO biosynthesis	25	1 of 4
66794	dTDPLrhamnose biosynthesis	25	2 of 8
66794	coenzyme A metabolism	25	1 of 4
66794	androgen and estrogen metabolism	25	4 of 16
66794	isoleucine metabolism	25	2 of 8
66794	degradation of sugar acids	24	6 of 25
66794	ascorbate metabolism	22.73	5 of 22
66794	nitrate assimilation	22.22	2 of 9

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
38565	-	-	+	+	-	+	-	-	-	-	-	+	-	-	-	+	-	-	-	-

API biotype100

@ref	ControlQ	D-glucose as carbon sourceGLU	D-fructose as carbon sourceFRU	D-galactose as carbon sourceGAL	D-trehalose as carbon sourceTRE	D-mannose as carbon sourceMNE	L-sorbose as carbon sourceSBE	D-melibiose as carbon sourceMEL	sucrose as carbon sourceSAC	D-raffinose as carbon sourceRAF	maltotriose as carbon sourceMTE	maltose as carbon sourceMAL	lactose as carbon sourceLAC	lactulose as carbon sourceLTE	1-O-methyl-beta-galactopyranoside as carbon sourceMbGa	1-O-methyl-alpha-galactopyranoside as carbon sourceMaGa	D-cellobiose as carbon sourceCEL	gentiobiose as carbon sourceGEN	1-O-methyl-beta-D-glucopyranoside as carbon sourceMbGu	esculin as carbon sourceESC	D-ribose as carbon sourceRIB	L-arabinose as carbon sourceARA	D-xylose as carbon sourceXYL	palatinose as carbon sourcePLE	L-rhamnose as carbon sourceRHA	L-fucose as carbon sourceFUC	D-melezitose as carbon sourceMLZ	D-arabitol as carbon sourceDARL	L-arabitol as carbon sourceLARL	xylitol as carbon sourceXLT	dulcitol as carbon sourceDUL	D-tagatose as carbon sourceTAG	glycerol as carbon sourceGLY	myo-inositol as carbon sourceINO	D-mannitol as carbon sourceMAN	maltitol as carbon sourceMTL	D-turanose as carbon sourceTUR	D-sorbitol as carbon sourceSOR	adonitol as carbon sourceADO	hydroxyquinoline-beta-glucuronide as carbon sourceHBG	D-lyxose as carbon sourceLYX	i-erythritol as carbon sourceERY	1-O-methyl-alpha-D-glucoside as carbon sourceMDG	3-O-methyl-D-glucose as carbon source3MDG	D-saccharate as carbon sourceSAT	mucate as carbon sourceMUC	L-tartrate as carbon sourceLTAT	D-tartrate as carbon sourceDTAT	meso-tartrate as carbon sourceMTAT	D-malate as carbon sourceDMLT	L-malate as carbon sourceLMLT	cis-aconitate as carbon sourceCATE	trans-aconitate as carbon sourceTATE	tricarballylate as carbon sourceTTE	citrate as carbon sourceCIT	D-glucuronate as carbon sourceGRT	D-galacturonate as carbon sourceGAT	2-ketogluconate as carbon source2KG	5-ketogluconate as carbon source5KG	tryptophan as carbon sourceTRY	N-acetyl-D-glucosamine as carbon sourceNAG	D-gluconate as carbon sourceGNT	phenylacetate as carbon sourcePAC	protocatechuate as carbon sourcePAT	4-hydroxybenzoate as carbon sourcepOBE	quinate as carbon sourceQAT	gentisate as carbon sourceGTE	3-hydroxybenzoate as carbon sourcemOBE	benzoate as carbon sourceBAT	3-phenylpropionate as carbon sourcePPAT	m-coumarate as carbon sourceCMT	trigonelline as carbon sourceTGE	betaine as carbon sourceBET	putrescine as carbon sourcePCE	4-aminobutyrate as carbon sourceABT	histamine as carbon sourceHIN	DL-lactate as carbon sourceLAT	caprate as carbon sourceCAP	caprylate as carbon sourceCYT	L-histidine as carbon sourceHIS	succinate as carbon sourceSUC	fumarate as carbon sourceFUM	glutarate as carbon sourceGRE	DL-glycerate as carbon sourceGYT	5-aminovalerate as carbon sourceAVT	ethanolamine as carbon sourceETN	tryptamine as carbon sourceTTN	D-glucosamine as carbon sourceGLN	itaconate as carbon sourceITA	3-hydroxybutyrate as carbon source3OBU	L-aspartate as carbon sourceAPT	L-glutamate as carbon sourceGTT	L-proline as carbon sourcePRO	D-alanine as carbon sourceDALA	L-alanine as carbon sourceLALA	L-serine as carbon sourceSER	malonate as carbon sourceMNT	propionate as carbon sourcePROP	L-tyrosine as carbon sourceTYR	2-ketoglutarate as carbon source2KT
38565	not determinedn.d.	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Host Body Product	#Fluids	#Blood
#Host	#Human	#Female

Isolation

@ref	Sample type	Host species	Country	Country ISO 3 Code	Continent
38565			Canada	CAN	North America
53658	Human blood,82-year-old woman	Homo sapiens	Canada	CAN	North America
38565	Human, Blood	Homo sapiens	Canada	CAN	North America

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
38565	1	Risk group (French classification)

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	Fack_igna_CCUG_37419_V1 assembly for Falseniella ignava CCUG 37419	scaffold	GCA_000301055	883112.3	2531839287	883112	67.19

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Fack_igna_CCUG_37419_V1 assembly for Falseniella ignava CCUG 37419
BV-BRC: 883112.3

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	facultative anaerobe	94.79	no
125439	gram_stain	BacteriaNetⓘ	positive	54.41	no
125439	motility	BacteriaNetⓘ	yes	49.40	no
125439	spore_formation	BacteriaNetⓘ	yes	67.57	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Facklamia ignava CCUG 37419 CCUG 37419
NCBI: GCA_000301055.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	85.79	no
125438	anaerobic	anaerobicⓘ	no	90.76	yes
125438	aerobic	aerobicⓘ	no	90.02	no
125438	spore-forming	spore-formingⓘ	no	87.30	no
125438	thermophilic	thermophileⓘ	no	93.40	no
125438	flagellated	motile2+ⓘ	no	92.00	no

Literature

Topic	Title	Authors	Journal	DOI	Year
Phylogeny	Streptococcus dysgalactiae subsp.-equisimilis as an emerging secondary pathogen in leprosy foot ulcers.	Ebineshan K, Pallapati MS, Srikantam A.	Iran J Microbiol	10.18502/ijm.v16i5.16795	2024
Metabolism	A glutaredoxin domain fused to the radical-generating subunit of ribonucleotide reductase (RNR) functions as an efficient RNR reductant.	Rozman Grinberg I, Lundin D, Sahlin M, Crona M, Berggren G, Hofer A, Sjoberg BM.	J Biol Chem	10.1074/jbc.ra118.004991	2018
Pathogenicity	Practical implications of erythromycin resistance gene diversity on surveillance and monitoring of resistance.	Choi J, Rieke EL, Moorman TB, Soupir ML, Allen HK, Smith SD, Howe A.	FEMS Microbiol Ecol	10.1093/femsec/fiy006	2018
Phylogeny	Facklamia Species as an Underrecognized Pathogen.	Rahmati E, Martin V, Wong D, Sattler F, Petterson J, Ward P, Butler-Wu SM, She RC.	Open Forum Infect Dis	10.1093/ofid/ofw272	2017
Phylogeny	Reclassification of Facklamia ignava, Facklamia sourekii and Facklamia tabacinasalis as Falseniella ignava gen. nov., comb. nov., Hutsoniella sourekii gen. nov., comb. nov., and Ruoffia tabacinasalis gen. nov., comb. nov., and description of Ruoffia halotolerans sp. nov., isolated from hypersaline Inland Sea of Qatar.	Fotedar R, Sankaranarayanan K, Caldwell ME, Zeyara A, Al Malki A, Kaul R, Al Shamari H, Ali M, Al Marri M, Lawson PA	Antonie Van Leeuwenhoek	10.1007/s10482-021-01587-7	2021
Phylogeny	Facklamia ignava sp. nov., isolated from human clinical specimens.	Collins MD, Lawson PA, Monasterio R, Falsen E, Sjoden B, Facklam RR	J Clin Microbiol	10.1128/JCM.36.7.2146-2148.1998	1998

References

#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#38565	Collection of Institut Pasteur ; Curators of the CIP; CIP 105583
#53658	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 37419
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#66794	Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg: BRENDA, the ELIXIR core data resource in 2021: new developments and updates. Nucleic Acids Res. 49: D498 - D508 2020 ( DOI 10.1093/nar/gkaa1025 , PubMed 33211880 )
#68382	Automatically annotated from API zym .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

Rate our new design

Content

About us

Facklamia ignava (CCM 4932, CIP 105583, CCUG 37419)

Name and taxonomic classification

Morphology

Cell morphology

Colony morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Metabolite utilization

Metabolite tests

Enzymes

Pathway annotation

API zym

API biotype100

Isolation, sampling and environmental information

Isolation source categories

Isolation

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_000301055

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

Help

Social Media