Enterococcus faecalis UW 700/95 is a facultative anaerobe, Gram-positive, coccus-shaped bacterium of the family Enterococcaceae.
Gram-positive coccus-shaped facultative anaerobe genome sequence Bacteria| @ref 20215 |
Last LPSN update
2026-02-09 11:32:52 |
| Domain Bacteria |
| Phylum Bacillota |
| Class Bacilli |
| Order Lactobacillales |
| Family Enterococcaceae |
| Genus Enterococcus |
| Species Enterococcus faecalis |
| Full scientific name Enterococcus faecalis (Andrewes and Horder 1906) Schleifer and Kilpper-Bälz 1984 |
| Synonyms (1) |
| 37261 | Oxygen tolerancefacultative anaerobe |
| @ref | Salt | Growth | Tested relation | Concentration | |
|---|---|---|---|---|---|
| 37261 | NaCl | positive | growth | 6.5 % |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68371 | 27613 ChEBI | amygdalin | + | builds acid from | from API 50CH acid |
| 68371 | 18305 ChEBI | arbutin | + | builds acid from | from API 50CH acid |
| 68371 | 17057 ChEBI | cellobiose | + | builds acid from | from API 50CH acid |
| 68371 | 17108 ChEBI | D-arabinose | - | builds acid from | from API 50CH acid |
| 68371 | 18333 ChEBI | D-arabitol | - | builds acid from | from API 50CH acid |
| 68371 | 15824 ChEBI | D-fructose | + | builds acid from | from API 50CH acid |
| 68371 | 28847 ChEBI | D-fucose | - | builds acid from | from API 50CH acid |
| 68371 | 12936 ChEBI | D-galactose | + | builds acid from | from API 50CH acid |
| 68371 | 17634 ChEBI | D-glucose | + | builds acid from | from API 50CH acid |
| 68371 | 62318 ChEBI | D-lyxose | - | builds acid from | from API 50CH acid |
| 68371 | 16899 ChEBI | D-mannitol | + | builds acid from | from API 50CH acid |
| 68371 | 16024 ChEBI | D-mannose | + | builds acid from | from API 50CH acid |
| 68371 | 16988 ChEBI | D-ribose | + | builds acid from | from API 50CH acid |
| 68371 | 17924 ChEBI | D-sorbitol | + | builds acid from | from API 50CH acid |
| 68371 | 16443 ChEBI | D-tagatose | + | builds acid from | from API 50CH acid |
| 68371 | 17113 ChEBI | erythritol | - | builds acid from | from API 50CH acid |
| 37261 | 4853 ChEBI | esculin | + | hydrolysis | |
| 68371 | 4853 ChEBI | esculin | + | builds acid from | from API 50CH acid |
| 68371 | 16813 ChEBI | galactitol | - | builds acid from | from API 50CH acid |
| 68371 | 28066 ChEBI | gentiobiose | + | builds acid from | from API 50CH acid |
| 68371 | 24265 ChEBI | gluconate | + | builds acid from | from API 50CH acid |
| 68371 | 17754 ChEBI | glycerol | + | builds acid from | from API 50CH acid |
| 68371 | 28087 ChEBI | glycogen | - | builds acid from | from API 50CH acid |
| 37261 | 606565 ChEBI | hippurate | + | hydrolysis | |
| 68371 | 15443 ChEBI | inulin | - | builds acid from | from API 50CH acid |
| 68371 | 30849 ChEBI | L-arabinose | - | builds acid from | from API 50CH acid |
| 68371 | 18403 ChEBI | L-arabitol | - | builds acid from | from API 50CH acid |
| 68371 | 18287 ChEBI | L-fucose | - | builds acid from | from API 50CH acid |
| 68371 | 62345 ChEBI | L-rhamnose | - | builds acid from | from API 50CH acid |
| 68371 | 17266 ChEBI | L-sorbose | - | builds acid from | from API 50CH acid |
| 68371 | 65328 ChEBI | L-xylose | - | builds acid from | from API 50CH acid |
| 68371 | 17716 ChEBI | lactose | + | builds acid from | from API 50CH acid |
| 68371 | 17306 ChEBI | maltose | + | builds acid from | from API 50CH acid |
| 68371 | 6731 ChEBI | melezitose | + | builds acid from | from API 50CH acid |
| 68371 | 28053 ChEBI | melibiose | - | builds acid from | from API 50CH acid |
| 68371 | 320061 ChEBI | methyl alpha-D-glucopyranoside | - | builds acid from | from API 50CH acid |
| 68371 | 43943 ChEBI | methyl alpha-D-mannoside | - | builds acid from | from API 50CH acid |
| 68371 | 74863 ChEBI | methyl beta-D-xylopyranoside | - | builds acid from | from API 50CH acid |
| 68371 | 17268 ChEBI | myo-inositol | - | builds acid from | from API 50CH acid |
| 68371 | 59640 ChEBI | N-acetylglucosamine | + | builds acid from | from API 50CH acid |
| 37261 | 17632 ChEBI | nitrate | - | reduction | |
| 37261 | 16301 ChEBI | nitrite | - | reduction | |
| 68371 | Potassium 2-ketogluconate | - | builds acid from | from API 50CH acid | |
| 68371 | Potassium 5-ketogluconate | + | builds acid from | from API 50CH acid | |
| 68371 | 16634 ChEBI | raffinose | - | builds acid from | from API 50CH acid |
| 68371 | 15963 ChEBI | ribitol | - | builds acid from | from API 50CH acid |
| 68371 | 17814 ChEBI | salicin | + | builds acid from | from API 50CH acid |
| 68371 | 28017 ChEBI | starch | + | builds acid from | from API 50CH acid |
| 68371 | 17992 ChEBI | sucrose | + | builds acid from | from API 50CH acid |
| 68371 | 27082 ChEBI | trehalose | + | builds acid from | from API 50CH acid |
| 68371 | 32528 ChEBI | turanose | - | builds acid from | from API 50CH acid |
| 68371 | 17151 ChEBI | xylitol | - | builds acid from | from API 50CH acid |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68382 | acid phosphatase | + | 3.1.3.2 | from API zym |
| 37261 | alcohol dehydrogenase | + | 1.1.1.1 | |
| 68382 | alkaline phosphatase | - | 3.1.3.1 | from API zym |
| 68382 | alpha-chymotrypsin | - | 3.4.21.1 | from API zym |
| 68382 | alpha-fucosidase | - | 3.2.1.51 | from API zym |
| 68382 | alpha-galactosidase | - | 3.2.1.22 | from API zym |
| 68382 | alpha-glucosidase | + | 3.2.1.20 | from API zym |
| 68382 | alpha-mannosidase | - | 3.2.1.24 | from API zym |
| 68382 | beta-galactosidase | + | 3.2.1.23 | from API zym |
| 37261 | beta-galactosidase | - | 3.2.1.23 | |
| 68382 | beta-glucosidase | - | 3.2.1.21 | from API zym |
| 68382 | beta-glucuronidase | - | 3.2.1.31 | from API zym |
| 37261 | catalase | - | 1.11.1.6 | |
| 68382 | cystine arylamidase | - | 3.4.11.3 | from API zym |
| 68382 | esterase (C 4) | + | from API zym | |
| 68382 | esterase lipase (C 8) | + | from API zym | |
| 37261 | gamma-glutamyltransferase | - | 2.3.2.2 | |
| 68382 | leucine arylamidase | + | 3.4.11.1 | from API zym |
| 68382 | lipase (C 14) | - | from API zym | |
| 37261 | lysine decarboxylase | - | 4.1.1.18 | |
| 68382 | N-acetyl-beta-glucosaminidase | + | 3.2.1.52 | from API zym |
| 68382 | naphthol-AS-BI-phosphohydrolase | + | from API zym | |
| 37261 | ornithine decarboxylase | - | 4.1.1.17 | |
| 37261 | oxidase | - | ||
| 68382 | trypsin | - | 3.4.21.4 | from API zym |
| 37261 | urease | - | 3.5.1.5 | |
| 68382 | valine arylamidase | - | from API zym |
| @ref | ControlQ | GLY | ERY | DARA | LARA | RIB | DXYL | LXYL | ADO | MDX | GAL | GLU | FRU | MNE | SBE | RHA | DUL | INO | MAN | SOR | MDM | MDG | NAG | AMY | ARB | ESC | SAL | CEL | MAL | LAC | MEL | SAC | TRE | INU | MLZ | RAF | AMD | GLYG | XLT | GEN | TUR | LYX | TAG | DFUC | LFUC | DARL | LARL | GNT | 2KG | 5KG | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 37261 | not determinedn.d. | + | - | - | - | + | +/- | - | - | - | + | + | + | + | - | - | - | - | + | + | - | - | + | + | + | + | + | + | + | + | - | + | + | - | + | - | + | - | - | + | - | - | + | - | - | - | - | + | - | + |
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|
| 124043 | ASM2240651v1 assembly for Enterococcus faecalis V583 ATCC 700802 | contig | GCA_022406515   | 226185.147  | 226185 | 33.07 | |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Hidden diversity in Enterococcus faecalis revealed by CRISPR2 screening: eco-evolutionary insights into a novel subspecies. | Leite VLM, Faria AR, Guerra CF, Souza SdSR, Freitas AdAR, Morais JM, Merquior VLC, Planet PJ, Teixeira LM. | Microbiol Spectr | 10.1128/spectrum.01428-25 | 2025 | | |
| Antimicrobial efficacy of blueM gel and calcium hydroxide against F. nucleatum and E. faecalis biofilm: an ex-vivo study. | Alharbi YR, Srivastava S, Alsalhi H, Almohimeed K, Alduraibi M, Nabil A. | Saudi Dent J | 10.1007/s44445-025-00042-x | 2025 | | |
| Exploring the Potential of Phytocannabinoids Against Multidrug-Resistant Bacteria. | Sirignano C, De Vita S, Gargiulo E, Lucidi M, Visaggio D, Chini MG, Lauro G, Chianese G, Visca P, Bifulco G, Taglialatela-Scafati O. | Plants (Basel) | 10.3390/plants14131901 | 2025 | | |
| Tailored structured peptide design with a key-cutting machine approach. | Leyva YC, Torres MDT, Oliva CA, de la Fuente-Nunez C, Brizuela CA. | Nat Mach Intell | 10.1038/s42256-025-01119-2 | 2025 | | |
| Enzymology | Studying the viability and growth kinetics of vancomycin-resistant Enterococcus faecalis V583 following femtosecond laser irradiation (420-465 nm). | El-Gendy AO, Ezzat S, Samad FA, Dabbous OA, Dahm J, Hamblin MR, Mohamed T. | Lasers Med Sci | 10.1007/s10103-024-04080-5 | 2024 | |
| Anti-biofilm Activity of Povidone-Iodine and Polyhexamethylene Biguanide: Evidence from In Vitro Tests. | Gryson L, Meaume S, Feldkaemper I, Favalli F. | Curr Microbiol | 10.1007/s00284-023-03257-5 | 2023 | | |
| Anti-biofilm Activity of a Lytic Phage Against Vancomycin-Resistant Enterococcus faecalis. | Goodarzi F, Hallajzadeh M, Sholeh M, Talebi M, Pirhajati Mahabadi V, Amirmozafari N. | Iran J Pathol | 10.30699/ijp.2022.541855.2760 | 2022 | | |
| Bacteriophages targeting Enterococcus faecalis enhance the therapeutic efficacy of levodopa in an MPTP-induced Parkinson's disease mouse model with E. faecalis gut colonization. | Hong JP, Shin S, Chung SH, Song MC, Shim JG, Kim Y, Lee B, Yeom M, Park HJ, Jung KH, Hong J, Hahm DH. | Sci Rep | 10.1038/s41598-024-77038-w | 2024 | | |
| Enterococcus-derived cytolysin exacerbates ischemic stroke by disrupting the blood-brain barrier via NLRP3 activation. | Huang JN, Zhuang WH, Lin YS, Xu JX, Zhang YL, Li J, Huang M, Xie CL, Xu RT. | J Neuroinflammation | 10.1186/s12974-025-03590-5 | 2025 | | |
| Antibacterial Activity of an FtsZ Inhibitor Celastrol and Its Synergistic Effect with Vancomycin against Enterococci In Vitro and In Vivo. | Lu X, Wang Y, Guo W, Zhang Z, Hu X, Nie T, Yang X, Li C, Wang X, Li X, Lu Y, Li G, Zhang Y, Sun L, Pang J, You X. | Microbiol Spectr | 10.1128/spectrum.03699-22 | 2023 | | |
| Chemoenzymatic Modification of Daptomycin: Aromatic Group Installation on Trp1. | Dimas DA, Kumar V, Mandal PS, Masterson JM, Tonelli M, Singh S. | Chembiochem | 10.1002/cbic.202400503 | 2024 | | |
| Pathogenicity | Enterococcus faecalis: an overlooked cell invader. | Archambaud C, Nunez N, da Silva RAG, Kline KA, Serror P. | Microbiol Mol Biol Rev | 10.1128/mmbr.00069-24 | 2024 | |
| Pathogenicity | Development of Low-Toxicity Antimicrobial Polycarbonates Bearing Lysine Residues. | Gao R, Xue M, Shen N, Zhao X, Zhang JC, Cao C, Cai J. | Chemistry | 10.1002/chem.202402302 | 2024 | |
| The effect of culturing temperature on the growth of the most dominant bacterial species of human gut microbiota and harmful bacterial species. | Shimokawa H, Sakakibara H, Ami Y, Hirano R, Kurihara S. | Biosci Microbiota Food Health | 10.12938/bmfh.2024-087 | 2025 | | |
| Characterization of Campylobacter jejuni proteome profiles in co-incubation scenarios. | Dreyer A, Lenz C, Gross U, Bohne W, Zautner AE. | Front Microbiol | 10.3389/fmicb.2023.1247211 | 2023 | | |
| Comparative analysis of proteomic adaptations in Enterococcus faecalis and Enterococcus faecium after long term bile acid exposure. | Dreyer A, Lenz C, Gross U, Bohne W, Zautner AE. | BMC Microbiol | 10.1186/s12866-024-03253-0 | 2024 | | |
| Effects of Osmotic Stress and Sodium Hypochlorite on Endodontic Microbiota: An In-Vitro Study. | Naicker D, Zilm P, Nagendrababu V, Rossi-Fedele G. | Eur Endod J | 10.14744/eej.2020.70883 | 2020 | | |
| Antimicrobial and Antibiofilm Activities of Some Antioxidant 3,4-Dihydroxyphenyl-Thiazole-Coumarin Hybrid Compounds: In Silico and In Vitro Evaluation. | Ungureanu D, Marc G, Duma MN, Tamaian R, Vodnar DC, Tiperciuc B, Moldovan C, Ionut I, Stana A, Oniga O. | Antibiotics (Basel) | 10.3390/antibiotics14090943 | 2025 | | |
| A Comparative Transcriptomic Analysis of Human Placental Trophoblasts in Response to Pathogenic and Probiotic Enterococcus faecalis Interaction. | Tan Q, Zeng Z, Xu F, Wei H. | Can J Infect Dis Med Microbiol | 10.1155/2021/6655414 | 2021 | | |
| The role of reactive oxygen species in the antimicrobial activity of pyochelin. | Ong KS, Cheow YL, Lee SM. | J Adv Res | 10.1016/j.jare.2017.05.007 | 2017 | | |
| Development of culture methods capable of culturing a wide range of predominant species of intestinal bacteria. | Hirano R, Nishita I, Nakai R, Bito A, Sasabe R, Kurihara S. | Front Cell Infect Microbiol | 10.3389/fcimb.2023.1056866 | 2023 | | |
| Antimicrobial betalains. | Wijesinghe VN, Choo WS. | J Appl Microbiol | 10.1111/jam.15798 | 2022 | | |
| A Boron-Dependent Antibiotic Derived from a Calcium-Dependent Antibiotic. | Chiou SL, Chen YJ, Lee CT, Ho MN, Miao J, Kuo PC, Hsu CC, Lin YS, Chu J. | Angew Chem Int Ed Engl | 10.1002/anie.202317522 | 2024 | | |
| Proteome | Deep learning reveals antibiotics in the archaeal proteome. | Torres MDT, Wan F, de la Fuente-Nunez C. | Nat Microbiol | 10.1038/s41564-025-02061-0 | 2025 | |
| Pathogenicity | Antimicrobial Guanidinylate Polycarbonates Show Oral In Vivo Efficacy Against Clostridioides Difficile. | Xue M, Chakraborty S, Gao R, Wang S, Gu M, Shen N, Wei L, Cao C, Sun X, Cai J. | Adv Healthc Mater | 10.1002/adhm.202303295 | 2024 | |
| Pharmacodynamics of ClpP-Activating Antibiotic Combinations against Gram-Positive Pathogens. | Mroue N, Arya A, Brown Gandt A, Russell C, Han A, Gavrish E, LaFleur M. | Antimicrob Agents Chemother | 10.1128/aac.01554-19 | 2019 | | |
| Development of lipidated polycarbonates with broad-spectrum antimicrobial activity. | Gao R, Li X, Xue M, Shen N, Wang M, Zhang J, Cao C, Cai J. | Biomater Sci | 10.1039/d2bm01995g | 2023 | | |
| Computational exploration of global venoms for antimicrobial discovery with Venomics artificial intelligence. | Guan C, Torres MDT, Li S, de la Fuente-Nunez C. | Nat Commun | 10.1038/s41467-025-60051-6 | 2025 | | |
| Nematode-Associated Bacteria: Production of Antimicrobial Agent as a Presumptive Nominee for Curing Endodontic Infections Caused by Enterococcus faecalis. | Donmez Ozkan H, Cimen H, Ulug D, Wenski S, Yigit Ozer S, Telli M, Aydin N, Bode HB, Hazir S. | Front Microbiol | 10.3389/fmicb.2019.02672 | 2019 | | |
| Exploring clinically isolated Staphylococcus sp. bacteriocins revealed the production of amonabactin, micrococcin, and alpha-circulocin. | Kassem MA, Saafan AE, Bayomy F, El-Gendy AO. | Iran J Microbiol | 10.18502/ijm.v13i2.5983 | 2021 | | |
| Freeze dried probiotic carrot juice powder for better storage stability of probiotic. | Rishabh D, Athira A, Preetha R, Nagamaniammai G. | J Food Sci Technol | 10.1007/s13197-021-05259-2 | 2023 | | |
| Testing of Anti-EMT, Anti-Inflammatory and Antibacterial Activities of 2',4'-Dimethoxychalcone. | Zhao P, Xu M, Gong K, Lu K, Ruan C, Yu X, Zhu J, Guan H, Zhu Q. | Pharmaceuticals (Basel) | 10.3390/ph17050653 | 2024 | | |
| Pathogenicity | Eradication of Vancomycin-Resistant Enterococci by Combining Phage and Vancomycin. | Shlezinger M, Coppenhagen-Glazer S, Gelman D, Beyth N, Hazan R. | Viruses | 10.3390/v11100954 | 2019 | |
| Metabolism | Expression of Interleukin-1beta and Matrix Metalloproteinase-8 in Cytolytic and Noncytolytic Enterococcus faecalis-induced Persistent Apical Periodontitis: A Comparative Study in the Rat. | Lu B, Zhang J, Huang X, Xiao S, Zhang M, Cai Z. | J Endod | 10.1016/j.joen.2015.04.019 | 2015 | |
| Phages in a thermoreversible sustained-release formulation targeting E. faecalis in vitro and in vivo. | Shlezinger M, Friedman M, Houri-Haddad Y, Hazan R, Beyth N. | PLoS One | 10.1371/journal.pone.0219599 | 2019 | | |
| Pathogenicity | Efficacy of low concentrations of sodium hypochlorite and low-powered Er,Cr:YSGG laser activated irrigation against an Enterococcus faecalis biofilm. | Christo JE, Zilm PS, Sullivan T, Cathro PR. | Int Endod J | 10.1111/iej.12447 | 2016 | |
| Mayan Medicinal Plants Bignonia potosina and Thouinia paucidentata Demonstrate Anti-Infective Properties Against the Priority Antibiotic-Resistant Bacteria Acinetobacter baumannii and Pseudomonas aeruginosa. | Molina-Salinas GM, Dzul-Beh A, Uc-Cachon AH, Dzib-Baak HE, Gonzalez-Sanchez AA, Palma-Pech GA, Quintal-Novelo CJ. | Plants (Basel) | 10.3390/plants13243498 | 2024 | | |
| Deep-learning-enabled antibiotic discovery through molecular de-extinction. | Wan F, Torres MDT, Peng J, de la Fuente-Nunez C. | Nat Biomed Eng | 10.1038/s41551-024-01201-x | 2024 | | |
| Lytic bacteriophages as alternative to overcoming antibiotic-resistant biofilms formed by clinically significant bacteria. | Osman AH, Darkwah S, Kotey FCN, Asante-Poku A, Donkor ES. | Ther Adv Infect Dis | 10.1177/20499361251356057 | 2025 | | |
| Chemoenzymatic synthesis of daptomycin analogs active against daptomycin-resistant strains. | Scull EM, Bandari C, Johnson BP, Gardner ED, Tonelli M, You J, Cichewicz RH, Singh S. | Appl Microbiol Biotechnol | 10.1007/s00253-020-10790-x | 2020 | | |
| Pathogenicity | Assessment of free fatty acids and cholesteryl esters delivered in liposomes as novel class of antibiotic. | Cheung Lam AH, Sandoval N, Wadhwa R, Gilkes J, Do TQ, Ernst W, Chiang SM, Kosina S, Howard Xu H, Fujii G, Porter E. | BMC Res Notes | 10.1186/s13104-016-2138-8 | 2016 | |
| Construction and characterization of a double mutant of Enterococcus faecalis that does not produce biogenic amines. | Perez M, Calles-Enriquez M, Del Rio B, Redruello B, de Jong A, Kuipers OP, Kok J, Martin MC, Ladero V, Fernandez M, Alvarez MA. | Sci Rep | 10.1038/s41598-019-53175-5 | 2019 | | |
| Liquid Extraction Surface Analysis Mass Spectrometry of ESKAPE Pathogens. | Havlikova J, May RC, Styles IB, Cooper HJ. | J Am Soc Mass Spectrom | 10.1021/jasms.0c00466 | 2021 | | |
| SSNOMBACTER: A collection of scattering-type scanning near-field optical microscopy and atomic force microscopy images of bacterial cells. | Lucidi M, Tranca DE, Nichele L, Unay D, Stanciu GA, Visca P, Holban AM, Hristu R, Cincotti G, Stanciu SG. | Gigascience | 10.1093/gigascience/giaa129 | 2020 | | |
| Defeating Antibiotic- and Phage-Resistant Enterococcus faecalis Using a Phage Cocktail in Vitro and in a Clot Model. | Khalifa L, Gelman D, Shlezinger M, Dessal AL, Coppenhagen-Glazer S, Beyth N, Hazan R. | Front Microbiol | 10.3389/fmicb.2018.00326 | 2018 | | |
| Pathogenicity | Surotomycin demonstrates low in vitro frequency of resistance and rapid bactericidal activity in Clostridium difficile, Enterococcus faecalis, and Enterococcus faecium. | Mascio CT, Chesnel L, Thorne G, Silverman JA. | Antimicrob Agents Chemother | 10.1128/aac.00124-14 | 2014 | |
| Biofilm in Endodontics: In Vitro Cultivation Possibilities, Sonic-, Ultrasonic- and Laser-Assisted Removal Techniques and Evaluation of the Cleaning Efficacy. | Josic U, Mazzitelli C, Maravic T, Fidler A, Breschi L, Mazzoni A. | Polymers (Basel) | 10.3390/polym14071334 | 2022 | | |
| Gut bacterial aromatic amine production: aromatic amino acid decarboxylase and its effects on peripheral serotonin production. | Sugiyama Y, Mori Y, Nara M, Kotani Y, Nagai E, Kawada H, Kitamura M, Hirano R, Shimokawa H, Nakagawa A, Minami H, Gotoh A, Sakanaka M, Iida N, Koyanagi T, Katayama T, Okamoto S, Kurihara S. | Gut Microbes | 10.1080/19490976.2022.2128605 | 2022 | | |
| Synthesis and Antimicrobial Properties of a Ciprofloxacin and PAMAM-dendrimer Conjugate. | Svenningsen SW, Frederiksen RF, Counil C, Ficker M, Leisner JJ, Christensen JB. | Molecules | 10.3390/molecules25061389 | 2020 | | |
| Engineered Lysins With Customized Lytic Activities Against Enterococci and Staphylococci. | Binte Muhammad Jai HS, Dam LC, Tay LS, Koh JJW, Loo HL, Kline KA, Goh BC. | Front Microbiol | 10.3389/fmicb.2020.574739 | 2020 | | |
| Genetics | Discovery of antimicrobial peptides in the global microbiome with machine learning. | Santos-Junior CD, Torres MDT, Duan Y, Rodriguez Del Rio A, Schmidt TSB, Chong H, Fullam A, Kuhn M, Zhu C, Houseman A, Somborski J, Vines A, Zhao XM, Bork P, Huerta-Cepas J, de la Fuente-Nunez C, Coelho LP. | Cell | 10.1016/j.cell.2024.05.013 | 2024 | |
| Phylogeny | A New High-Throughput Screening Method for Phages: Enabling Crude Isolation and Fast Identification of Diverse Phages with Therapeutic Potential. | Olsen NS, Hendriksen NB, Hansen LH, Kot W. | Phage (New Rochelle) | 10.1089/phage.2020.0016 | 2020 | |
| Phylogeny | Comparison of genotypic and phylogenetic relationships of environmental Enterococcus isolates by BOX-PCR typing and 16S rRNA gene sequencing. | Nayak BS, Badgley B, Harwood VJ. | Appl Environ Microbiol | 10.1128/aem.00130-11 | 2011 | |
| Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II binding. | Parmar A, Iyer A, Prior SH, Lloyd DG, Leng Goh ET, Vincent CS, Palmai-Pallag T, Bachrati CZ, Breukink E, Madder A, Lakshminarayanan R, Taylor EJ, Singh I. | Chem Sci | 10.1039/c7sc03241b | 2017 | | |
| Pathogenicity | Interference with Lipoprotein Maturation Sensitizes Methicillin-Resistant Staphylococcus aureus to Human Group IIA-Secreted Phospholipase A2 and Daptomycin. | Kuijk MM, Wu Y, van Hensbergen VP, Shanlitourk G, Payre C, Lambeau G, Man-Bovenkerk S, Herrmann J, Muller R, van Strijp JAG, Pannekoek Y, Touqui L, van Sorge NM. | J Innate Immun | 10.1159/000527549 | 2023 | |
| Axiom Microbiome Array, the next generation microarray for high-throughput pathogen and microbiome analysis. | Thissen JB, Be NA, McLoughlin K, Gardner S, Rack PG, Shapero MH, Rowland RRR, Slezak T, Jaing CJ. | PLoS One | 10.1371/journal.pone.0212045 | 2019 | | |
| Metabolism | Prevention of Anastomotic Leak Via Local Application of Tranexamic Acid to Target Bacterial-mediated Plasminogen Activation: A Practical Solution to a Complex Problem. | Jacobson RA, Williamson AJ, Wienholts K, Gaines S, Hyoju S, van Goor H, Zaborin A, Shogan BD, Zaborina O, Alverdy JC. | Ann Surg | 10.1097/sla.0000000000003733 | 2021 | |
| Genetics | Targeting Enterococcus faecalis biofilms with phage therapy. | Khalifa L, Brosh Y, Gelman D, Coppenhagen-Glazer S, Beyth S, Poradosu-Cohen R, Que YA, Beyth N, Hazan R. | Appl Environ Microbiol | 10.1128/aem.00096-15 | 2015 | |
| Pathogenicity | Antibacterial activity of lipo-alpha/sulfono-gamma-AA hybrid peptides. | Wei L, Wang M, Gao R, Fatirkhorani R, Cai J. | Eur J Med Chem | 10.1016/j.ejmech.2019.111901 | 2020 | |
| Pathogenicity | The Activity of Small Urea-gamma-AApeptides Toward Gram-Positive Bacteria. | Su M, Shi Y, Wang M, Gao R, Wu J, Xu H, Xi C, Cai J. | ChemMedChem | 10.1002/cmdc.201900520 | 2019 | |
| Fighting Pathogenic Bacteria on Two Fronts: Phages and Antibiotics as Combined Strategy. | Tagliaferri TL, Jansen M, Horz HP. | Front Cell Infect Microbiol | 10.3389/fcimb.2019.00022 | 2019 | | |
| Pathogenicity | A novel engineered peptide, a narrow-spectrum antibiotic, is effective against vancomycin-resistant Enterococcus faecalis. | Qiu XQ, Zhang J, Wang H, Wu GY. | Antimicrob Agents Chemother | 10.1128/aac.49.3.1184-1189.2005 | 2005 | |
| Metabolism | Identification and imaging of peptides and proteins on Enterococcus faecalis biofilms by matrix assisted laser desorption ionization mass spectrometry. | M T MB, Aydin B, Carlson RP, Hanley L. | Analyst | 10.1039/c2an35922g | 2012 | |
| Metabolism | The Heterodimeric ABC Transporter EfrCD Mediates Multidrug Efflux in Enterococcus faecalis. | Hurlimann LM, Corradi V, Hohl M, Bloemberg GV, Tieleman DP, Seeger MA. | Antimicrob Agents Chemother | 10.1128/aac.00661-16 | 2016 | |
| Pathogenicity | Enrichment of human IgA-coated bacterial vesicles in ulcerative colitis as a driver of inflammation. | Thapa HB, Passegger CA, Fleischhacker D, Kohl P, Chen YC, Kalawong R, Tam-Amersdorfer C, Gerstorfer MR, Strahlhofer J, Schild-Prufert K, Zechner EL, Blesl A, Binder L, Busslinger GA, Eberl L, Gorkiewicz G, Strobl H, Hogenauer C, Schild S. | Nat Commun | 10.1038/s41467-025-59354-5 | 2025 | |
| Metabolism | Using a genome-scale metabolic model of Enterococcus faecalis V583 to assess amino acid uptake and its impact on central metabolism. | Veith N, Solheim M, van Grinsven KW, Olivier BG, Levering J, Grosseholz R, Hugenholtz J, Holo H, Nes I, Teusink B, Kummer U. | Appl Environ Microbiol | 10.1128/aem.03279-14 | 2015 | |
| Pathogenicity | Mutations associated with reduced surotomycin susceptibility in Clostridium difficile and Enterococcus species. | Adams HM, Li X, Mascio C, Chesnel L, Palmer KL. | Antimicrob Agents Chemother | 10.1128/aac.00526-15 | 2015 | |
| Metabolism | Escherichia coli enoyl-acyl carrier protein reductase (FabI) supports efficient operation of a functional reversal of beta-oxidation cycle. | Vick JE, Clomburg JM, Blankschien MD, Chou A, Chou A, Kim S, Gonzalez R. | Appl Environ Microbiol | 10.1128/aem.03521-14 | 2015 | |
| Synthetic antibacterial minerals: harnessing a natural geochemical reaction to combat antibiotic resistance. | Morrison KD, Martin KA, Wimpenny JB, Loots GG. | Sci Rep | 10.1038/s41598-022-05303-x | 2022 | | |
| Pathogenicity | Lipidated alpha/alpha-AA heterogeneous peptides as antimicrobial agents. | Singh S, Nimmagadda A, Su M, Wang M, Teng P, Cai J. | Eur J Med Chem | 10.1016/j.ejmech.2018.06.006 | 2018 | |
| A common protocol for the simultaneous processing of multiple clinically relevant bacterial species for whole genome sequencing. | Raven KE, Girgis ST, Akram A, Blane B, Leek D, Brown N, Peacock SJ. | Sci Rep | 10.1038/s41598-020-80031-8 | 2021 | | |
| Metabolism | Proteomic Investigation of the Response of Enterococcus faecalis V583 when Cultivated in Urine. | Arntzen MO, Karlskas IL, Skaugen M, Eijsink VG, Mathiesen G. | PLoS One | 10.1371/journal.pone.0126694 | 2015 | |
| Pathogenicity | Modular Design of Membrane-Active Antibiotics: From Macromolecular Antimicrobials to Small Scorpionlike Peptidomimetics. | Wang M, Feng X, Gao R, Sang P, Pan X, Wei L, Lu C, Wu C, Cai J. | J Med Chem | 10.1021/acs.jmedchem.1c00312 | 2021 | |
| Adaptively evolved human oral actinomyces-sourced defensins show therapeutic potential. | Zhu S, Gao B, Umetsu Y, Peigneur S, Li P, Ohki S, Tytgat J. | EMBO Mol Med | 10.15252/emmm.202114499 | 2022 | | |
| Computational Design of Pore-Forming Peptides with Potent Antimicrobial and Anticancer Activities. | Deb R, Torres MDT, Boudny M, Koberska M, Cappiello F, Popper M, Dvorakova Bendova K, Drabinova M, Hanackova A, Jeannot K, Petrik M, Mangoni ML, Balikova Novotna G, Mraz M, de la Fuente-Nunez C, Vacha R. | J Med Chem | 10.1021/acs.jmedchem.4c00912 | 2024 | | |
| In vivo antibacterial activity of MRX-I, a new oxazolidinone. | Li CR, Zhai QQ, Wang XK, Hu XX, Li GQ, Zhang WX, Pang J, Lu X, Yuan H, Gordeev MF, Chen LT, Yang XY, You XF. | Antimicrob Agents Chemother | 10.1128/aac.01526-13 | 2014 | | |
| Metabolism | A Listeria monocytogenes Bacteriocin Can Target the Commensal Prevotella copri and Modulate Intestinal Infection. | Rolhion N, Chassaing B, Nahori MA, de Bodt J, Moura A, Lecuit M, Dussurget O, Berard M, Marzorati M, Fehlner-Peach H, Littman DR, Gewirtz AT, Van de Wiele T, Cossart P. | Cell Host Microbe | 10.1016/j.chom.2019.10.016 | 2019 | |
| SNP diversity of Enterococcus faecalis and Enterococcus faecium in a South East Queensland waterway, Australia, and associated antibiotic resistance gene profiles. | Rathnayake I, Hargreaves M, Huygens F. | BMC Microbiol | 10.1186/1471-2180-11-201 | 2011 | | |
| Metabolism | The structure and competitive substrate inhibition of dihydrofolate reductase from Enterococcus faecalis reveal restrictions to cofactor docking. | Bourne CR, Wakeham N, Webb N, Nammalwar B, Bunce RA, Berlin KD, Barrow WW. | Biochemistry | 10.1021/bi401104t | 2014 | |
| Enzymology | Quantification of bacterial indicators and zoonotic pathogens in dairy wastewater ponds. | Dungan RS, Klein M, Leytem AB. | Appl Environ Microbiol | 10.1128/aem.02470-12 | 2012 | |
| The development of antimicrobial a-AApeptides that suppress proinflammatory immune responses. | Padhee S, Smith C, Wu H, Li Y, Manoj N, Qiao Q, Khan Z, Cao C, Yin H, Cai J. | Chembiochem | 10.1002/cbic.201300709 | 2014 | | |
| Pathogenicity | Bacterial Long-Range Warfare: Aerial Killing of Legionella pneumophila by Pseudomonas fluorescens. | Corre MH, Mercier A, Bouteiller M, Khalil A, Ginevra C, Depayras S, Dupont C, Rouxel M, Gallique M, Grac L, Jarraud S, Giron D, Merieau A, Berjeaud JM, Verdon J. | Microbiol Spectr | 10.1128/spectrum.00404-21 | 2021 | |
| Pathogenicity | Modified lactic acid bacteria detect and inhibit multiresistant enterococci. | Borrero J, Chen Y, Dunny GM, Kaznessis YN. | ACS Synth Biol | 10.1021/sb500090b | 2015 | |
| Phylogeny | Integrated Counts of Carbohydrate-Active Protein Domains as Metabolic Readouts to Distinguish Probiotic Biology and Human Fecal Metagenomes. | Liu HH, Lin YC, Chung CS, Liu K, Chang YH, Yang CH, Chen Y, Ni YH, Chang PF. | Sci Rep | 10.1038/s41598-019-53173-7 | 2019 | |
| Small Antimicrobial Agents Based on Acylated Reduced Amide Scaffold. | Teng P, Huo D, Nimmagadda A, Wu J, She F, Su M, Lin X, Yan J, Cao A, Xi C, Hu Y, Cai J. | J Med Chem | 10.1021/acs.jmedchem.6b00640 | 2016 | | |
| Metabolism | Novel endo-alpha-N-acetylgalactosaminidases with broader substrate specificity. | Koutsioulis D, Landry D, Guthrie EP. | Glycobiology | 10.1093/glycob/cwn069 | 2008 | |
| Pathogenicity | Quantification of antibiotic in biofilm-inhibiting multilayers by 7.87 eV laser desorption postionization MS imaging. | Blaze M T M, Akhmetov A, Aydin B, Edirisinghe PD, Uygur G, Hanley L. | Anal Chem | 10.1021/ac302230e | 2012 | |
| Enzymology | Characterization and kinetics of phosphopantothenoylcysteine synthetase from Enterococcus faecalis. | Yao J, Patrone JD, Dotson GD. | Biochemistry | 10.1021/bi802240w | 2009 | |
| Metabolism | Rapid synthesis, RNA binding, and antibacterial screening of a peptidic-aminosugar (PA) library. | Jiang L, Watkins D, Jin Y, Gong C, King A, Washington AZ, Green KD, Garneau-Tsodikova S, Oyelere AK, Arya DP. | ACS Chem Biol | 10.1021/cb5010367 | 2015 | |
| Genetic variation and evolution of the pathogenicity island of Enterococcus faecalis. | McBride SM, Coburn PS, Baghdayan AS, Willems RJ, Grande MJ, Shankar N, Gilmore MS. | J Bacteriol | 10.1128/jb.00031-09 | 2009 | | |
| Phylogeny | Isothermal assay targeting class 1 integrase gene for environmental surveillance of antibiotic resistance markers. | Stedtfeld RD, Stedtfeld TM, Waseem H, Fitschen-Brown M, Guo X, Chai B, Williams MR, Shook T, Logan A, Graham A, Chae JC, Sul WJ, VanHouten J, Cole JR, Zylstra GJ, Tiedje JM, Upham BL, Hashsham SA. | J Environ Manage | 10.1016/j.jenvman.2017.04.079 | 2017 | |
| Metabolism | Structural and biochemical analysis of the pentapeptide repeat protein EfsQnr, a potent DNA gyrase inhibitor. | Hegde SS, Vetting MW, Mitchenall LA, Maxwell A, Blanchard JS. | Antimicrob Agents Chemother | 10.1128/aac.01158-10 | 2011 | |
| Serological and genetic diversity of capsular polysaccharides in Enterococcus faecalis. | Hufnagel M, Hancock LE, Koch S, Theilacker C, Gilmore MS, Huebner J. | J Clin Microbiol | 10.1128/jcm.42.6.2548-2557.2004 | 2004 | | |
| The immune properties of Manduca sexta transferrin. | Brummett LM, Kanost MR, Gorman MJ. | Insect Biochem Mol Biol | 10.1016/j.ibmb.2016.12.006 | 2017 | | |
| Pathogenicity | Antimicrobial AApeptides. | Sang P, Shi Y, Teng P, Cao A, Xu H, Li Q, Cai J. | Curr Top Med Chem | 10.2174/1568026616666161018145945 | 2017 | |
| Phylogeny | Direct detection of nasal Staphylococcus aureus carriage via helicase-dependent isothermal amplification and chip hybridization. | Frech GC, Munns D, Jenison RD, Hicke BJ. | BMC Res Notes | 10.1186/1756-0500-5-430 | 2012 | |
| Pathogenicity | Covalent dimer species of beta-defensin Defr1 display potent antimicrobial activity against multidrug-resistant bacterial pathogens. | Taylor K, McCullough B, Clarke DJ, Langley RJ, Pechenick T, Hill A, Campopiano DJ, Barran PE, Dorin JR, Govan JR. | Antimicrob Agents Chemother | 10.1128/aac.01531-06 | 2007 | |
| Pathogenicity | Peptide fragments of a beta-defensin derivative with potent bactericidal activity. | Reynolds NL, De Cecco M, Taylor K, Stanton C, Stanton C, Kilanowski F, Kalapothakis J, Seo E, Uhrin D, Campopiano D, Govan J, Macmillan D, Barran P, Dorin JR. | Antimicrob Agents Chemother | 10.1128/aac.01568-09 | 2010 | |
| Metabolism | Chloride-Inducible Expression Vector for Delivery of Antimicrobial Peptides Targeting Antibiotic-Resistant Enterococcus faecium. | Geldart K, Borrero J, Kaznessis YN. | Appl Environ Microbiol | 10.1128/aem.00227-15 | 2015 | |
| Chemical modification of capuramycins to enhance antibacterial activity. | Bogatcheva E, Dubuisson T, Protopopova M, Einck L, Nacy CA, Reddy VM. | J Antimicrob Chemother | 10.1093/jac/dkq495 | 2011 | | |
| Metabolism | Bacterial swimmers that infiltrate and take over the biofilm matrix. | Houry A, Gohar M, Deschamps J, Tischenko E, Aymerich S, Gruss A, Briandet R. | Proc Natl Acad Sci U S A | 10.1073/pnas.1200791109 | 2012 | |
| Metabolism | High-level production of amorpha-4,11-diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli. | Tsuruta H, Paddon CJ, Eng D, Lenihan JR, Horning T, Anthony LC, Regentin R, Keasling JD, Renninger NS, Newman JD. | PLoS One | 10.1371/journal.pone.0004489 | 2009 | |
| Metabolism | Lipids including cholesteryl linoleate and cholesteryl arachidonate contribute to the inherent antibacterial activity of human nasal fluid. | Do TQ, Moshkani S, Castillo P, Anunta S, Pogosyan A, Cheung A, Marbois B, Faull KF, Ernst W, Chiang SM, Fujii G, Clarke CF, Foster K, Porter E. | J Immunol | 10.4049/jimmunol.181.6.4177 | 2008 | |
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| Antimicrobial activity of a novel catheter lock solution. | Shah CB, Mittelman MW, Costerton JW, Parenteau S, Pelak M, Arsenault R, Mermel LA. | Antimicrob Agents Chemother | 10.1128/aac.46.6.1674-1679.2002 | 2002 | | |
| Recent advances in the chemistry and biology of naturally occurring antibiotics. | Nicolaou KC, Chen JS, Edmonds DJ, Estrada AA. | Angew Chem Int Ed Engl | 10.1002/anie.200801695 | 2009 | | |
| Transcriptome | Burkholderia paludis sp. nov., an Antibiotic-Siderophore Producing Novel Burkholderia cepacia Complex Species, Isolated from Malaysian Tropical Peat Swamp Soil. | Ong KS, Aw YK, Lee LH, Yule CM, Cheow YL, Lee SM. | Front Microbiol | 10.3389/fmicb.2016.02046 | 2016 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive137332.20251217.10
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
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