Mycobacterium mucogenicum (CIP 105223, DSM 44625, JCM 13575)

Name: Mycobacterium mucogenicum (CIP 105223, DSM 44625, JCM 13575)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 136780

Type strain

Strain Designation MO24, Mo 24

Culture col. no. CIP 105223 DSM 44625 JCM 13575 ATCC 49650 CDC 86-701 4 more

NCBI tax ID(s) 56689

Special Collections DSMZ CCUG JCM KCTC CIP

History <- CIP; CIP 105223 <- R. J. WallaceJr, Univ. Texas; Mo 24 <- R. Belizaire; CIP 105223 <-- R. J. Wallace, Jr. Mo 24 <-- R. Belizaire. CIP <- 1997, R.J. Wallace, Univ. Texas, USA: strain MO 24 <- R. Belizaire, Midland, TX, USA

Links

Mycobacterium mucogenicum MO24 is an obligate aerobe, mesophilic, rod-shaped prokaryote of the family Mycobacteriaceae.

rod-shaped obligate aerobe mesophilic 16S sequence

Name and taxonomic classification

SI-ID 42603

ATCC 49650,CIP 105223,DSM 44625,CCUG 47451,KCTC 19088,JCM 13575,CCUG 55497

@ref 20215

Last LPSN update 2025-12-16 10:02:39

Domain Bacillati

Phylum Actinomycetota

Class Actinomycetes

Order Mycobacteriales

Family Mycobacteriaceae

Genus Mycobacterium

Species Mycobacterium mucogenicum

Full scientific name Mycobacterium mucogenicum Springer et al. 1995

Synonyms (1)

Mycolicibacterium mucogenicum

BacDive ID	Other strains from **Mycobacterium mucogenicum** (10)	Type strain
8450	M. mucogenicum MO12, 77-590, MO 12, DSM 44124, ATCC 49649, ...
136781	M. mucogenicum MO135, CIP 105224, ATCC 49651, CCUG 42425
144485	M. mucogenicum CCUG 25238
153917	M. mucogenicum CCUG 51636
154155	M. mucogenicum CCUG 52584
154202	M. mucogenicum CCUG 52719 B
154227	M. mucogenicum CCUG 52812
154259	M. mucogenicum CCUG 52907 B
154439	M. mucogenicum CCUG 53623
154599	M. mucogenicum CCUG 54546

Morphology

Cell morphology

@ref	Cell shape	Motility
36363	rod-shaped

Multimedia

@ref:	11937
multimedia content:	DSM_44625.jpg
multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_44625.jpg
caption:	Medium 645 37°C
intellectual property rights:	© Leibniz-Institut DSMZ
manual_annotation:	1

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
36363	MEDIUM 72- for trypto casein soja agar		Distilled water make up to (1000.000 ml);Trypto casein soy agar (40.000 g)
11937	MIDDLEBROOK MEDIUM (DSMZ Medium 645)	Medium recipe at MediaDive	Name: MIDDLEBROOK MEDIUM (DSMZ Medium 645) Composition: Bacto Middlebrook 7H10 agar 20.9945 g/l Glycerol Distilled water
36363	CIP Medium 72	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)	Range
11937	positive	growth	37	mesophilic
36363	positive	growth	30	mesophilic
36363	negative	growth	10
36363	negative	growth	22
36363	negative	growth	45
67770	positive	growth	37	mesophilic

Physiology and metabolism

Oxygen tolerance

36363

Oxygen toleranceobligate aerobe

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
36363	606565 ChEBI	hippurate	-	hydrolysis
36363	17632 ChEBI	nitrate	-	reduction
36363	17632 ChEBI	nitrate	-	respiration
36363	16301 ChEBI	nitrite	-	reduction

Metabolite production

@ref	Chebi-ID	Metabolite	Production
36363	35581 ChEBI	indole

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
68382	alkaline phosphatase	-	3.1.3.1	from API zym
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68382	alpha-glucosidase	-	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
36363	amylase	-
68382	beta-galactosidase	-	3.2.1.23	from API zym
36363	beta-galactosidase	+	3.2.1.23
68382	beta-glucosidase	+	3.2.1.21	from API zym
68382	beta-glucuronidase	-	3.2.1.31	from API zym
36363	caseinase	-	3.4.21.50
36363	catalase	+	1.11.1.6
68382	cystine arylamidase	-	3.4.11.3	from API zym
36363	DNase	-
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
36363	gamma-glutamyltransferase	-	2.3.2.2
36363	gelatinase	-
36363	lecithinase	-
68382	leucine arylamidase	+	3.4.11.1	from API zym
36363	lipase	-
68382	lipase (C 14)	+		from API zym
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
36363	oxidase	+
36363	protease	-
68382	trypsin	-	3.4.21.4	from API zym
36363	tween esterase	-
36363	urease	-	3.5.1.5
68382	valine arylamidase	-		from API zym

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
36363	-	-	+	+	+	+	-	-	-	-	+	+	-	-	-	-	+	-	-	-

API biotype100

@ref	ControlQ	D-glucose as carbon sourceGLU	D-fructose as carbon sourceFRU	D-galactose as carbon sourceGAL	D-trehalose as carbon sourceTRE	D-mannose as carbon sourceMNE	L-sorbose as carbon sourceSBE	D-melibiose as carbon sourceMEL	sucrose as carbon sourceSAC	D-raffinose as carbon sourceRAF	maltotriose as carbon sourceMTE	maltose as carbon sourceMAL	lactose as carbon sourceLAC	lactulose as carbon sourceLTE	1-O-methyl-beta-galactopyranoside as carbon sourceMbGa	1-O-methyl-alpha-galactopyranoside as carbon sourceMaGa	D-cellobiose as carbon sourceCEL	gentiobiose as carbon sourceGEN	1-O-methyl-beta-D-glucopyranoside as carbon sourceMbGu	esculin as carbon sourceESC	D-ribose as carbon sourceRIB	L-arabinose as carbon sourceARA	D-xylose as carbon sourceXYL	palatinose as carbon sourcePLE	L-rhamnose as carbon sourceRHA	L-fucose as carbon sourceFUC	D-melezitose as carbon sourceMLZ	D-arabitol as carbon sourceDARL	L-arabitol as carbon sourceLARL	xylitol as carbon sourceXLT	dulcitol as carbon sourceDUL	D-tagatose as carbon sourceTAG	glycerol as carbon sourceGLY	myo-inositol as carbon sourceINO	D-mannitol as carbon sourceMAN	maltitol as carbon sourceMTL	D-turanose as carbon sourceTUR	D-sorbitol as carbon sourceSOR	adonitol as carbon sourceADO	hydroxyquinoline-beta-glucuronide as carbon sourceHBG	D-lyxose as carbon sourceLYX	i-erythritol as carbon sourceERY	1-O-methyl-alpha-D-glucoside as carbon sourceMDG	3-O-methyl-D-glucose as carbon source3MDG	D-saccharate as carbon sourceSAT	mucate as carbon sourceMUC	L-tartrate as carbon sourceLTAT	D-tartrate as carbon sourceDTAT	meso-tartrate as carbon sourceMTAT	D-malate as carbon sourceDMLT	L-malate as carbon sourceLMLT	cis-aconitate as carbon sourceCATE	trans-aconitate as carbon sourceTATE	tricarballylate as carbon sourceTTE	citrate as carbon sourceCIT	D-glucuronate as carbon sourceGRT	D-galacturonate as carbon sourceGAT	2-ketogluconate as carbon source2KG	5-ketogluconate as carbon source5KG	tryptophan as carbon sourceTRY	N-acetyl-D-glucosamine as carbon sourceNAG	D-gluconate as carbon sourceGNT	phenylacetate as carbon sourcePAC	protocatechuate as carbon sourcePAT	4-hydroxybenzoate as carbon sourcepOBE	quinate as carbon sourceQAT	gentisate as carbon sourceGTE	3-hydroxybenzoate as carbon sourcemOBE	benzoate as carbon sourceBAT	3-phenylpropionate as carbon sourcePPAT	m-coumarate as carbon sourceCMT	trigonelline as carbon sourceTGE	betaine as carbon sourceBET	putrescine as carbon sourcePCE	4-aminobutyrate as carbon sourceABT	histamine as carbon sourceHIN	DL-lactate as carbon sourceLAT	caprate as carbon sourceCAP	caprylate as carbon sourceCYT	L-histidine as carbon sourceHIS	succinate as carbon sourceSUC	fumarate as carbon sourceFUM	glutarate as carbon sourceGRE	DL-glycerate as carbon sourceGYT	5-aminovalerate as carbon sourceAVT	ethanolamine as carbon sourceETN	tryptamine as carbon sourceTTN	D-glucosamine as carbon sourceGLN	itaconate as carbon sourceITA	3-hydroxybutyrate as carbon source3OBU	L-aspartate as carbon sourceAPT	L-glutamate as carbon sourceGTT	L-proline as carbon sourcePRO	D-alanine as carbon sourceDALA	L-alanine as carbon sourceLALA	L-serine as carbon sourceSER	malonate as carbon sourceMNT	propionate as carbon sourcePROP	L-tyrosine as carbon sourceTYR	2-ketoglutarate as carbon source2KT
36363	not determinedn.d.	+	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	+	-	-	-	-	-	+	+	-	-	-	-	-	-	-	-	-	-	+	+	+	-	+	-	+	-	+	+	-	-	-	+	-	+	-	-	+	+	-	+	+	+	-	+	-	+

Isolation, sampling and environmental information

Isolation

@ref	Sample type	Geographic location	Country	Country ISO 3 Code	Continent	Isolation date
36363		Midland, TX	USA	USA	North America
67770	Infected thyroglossal duct cyst	TX	USA	USA	North America
36363	Thyroglossal duct cyst	Midland, Texas	United States of America	USA	North America	1986
11937	thyroglossal duct cyst	Texas, Midland	USA	USA	North America

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
11937	2	Risk group (German classification) According to TRBA 466
36363	1	Risk group (French classification) According to TRBA 466

Sequence information

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
67770	Mycobacterium mucogenicum partial 16S rRNA gene, strain CCUG 47451	AM902750	1380	56689
67770	Mycolicibacterium mucogenicum strain ATCC 49650 16S ribosomal RNA gene, partial sequence	AY457074	1482	56689
67770	Mycobacterium Chelonae-like organism 16S rRNA gene	X80771	1073	1774
124043	Mycobacterium mucogenicum strain ATCC 49650 16S ribosomal RNA gene, partial sequence.	AF480586	1455	56689
124043	Mycolicibacterium mucogenicum strain ATCC 49650 16S ribosomal RNA gene, partial sequence.	OR801628	1482	56689
124043	Mycobacterium mucogenicum strain CIP 105223 16S ribosomal RNA gene, partial sequence.	AF547949	540	56689

Genome-based predictions

Literature

Topic	Title	Authors	Journal	DOI	Year
	A single-step sequencing method for the identification of Mycobacterium tuberculosis complex species.	Djelouadji Z, Raoult D, Daffe M, Drancourt M.	PLoS Negl Trop Dis	10.1371/journal.pntd.0000253	2008
	Epidemiology, clinical presentation, and predictors of outcome in nontuberculous mycobacterial central nervous system infection: a systematic review.	Meena DS, Kumar D, Meena V, Bohra GK, Tak V, Garg MK.	Trop Med Health	10.1186/s41182-023-00546-4	2023
	In vitro Susceptibility of Nontuberculous Mycobacteria to Tedizolid.	Zhang H, Hua W, Lin S, Zhang Y, Chen X, Wang S, Chen J, Zhang W.	Infect Drug Resist	10.2147/idr.s362583	2022
Metabolism	Comparison of Macrophage Immune Responses and Metabolic Reprogramming in Smooth and Rough Variant Infections of Mycobacterium mucogenicum.	Kang M, Kim HW, Yu AR, Yang JS, Lee SH, Lee JW, Yoon HS, Lee BS, Park HW, Lee SK, Lee S, Whang J, Kim JS.	Int J Mol Sci	10.3390/ijms23052488	2022
Phylogeny	Lack of usefulness of carbon utilization tests for identification of Mycobacterium mucogenicum.	Conville PS, Witebsky FG.	J Clin Microbiol	10.1128/jcm.39.7.2725-2728.2001	2001
Pathogenicity	In vitro susceptibilities of rapidly growing mycobacteria to telithromycin (HMR 3647) and seven other antimicrobials.	Fernandez-Roblas R, Esteban J, Cabria F, Lopez JC, Jimenez MS, Soriano F.	Antimicrob Agents Chemother	10.1128/aac.44.1.181-182.2000	2000
Enzymology	Evaluation of the invader assay with the BACTEC MGIT 960 system for prompt isolation and identification of mycobacterial species from clinical specimens.	Ichimura S, Nagano M, Ito N, Shimojima M, Egashira T, Miyamoto C, Ohkusu K, Ezaki T.	J Clin Microbiol	10.1128/jcm.02289-06	2007
Pathogenicity	Activities of the glycylcyclines N,N-dimethylglycylamido-minocycline and N,N-dimethylglycylamido-6-demethyl-6-deoxytetracycline against Nocardia spp. and tetracycline-resistant isolates of rapidly growing mycobacteria.	Brown BA, Wallace RJ, Onyi G.	Antimicrob Agents Chemother	10.1128/aac.40.4.874	1996
Phylogeny	Phylogenomics and Comparative Genomic Studies Robustly Support Division of the Genus Mycobacterium into an Emended Genus Mycobacterium and Four Novel Genera.	Gupta RS, Lo B, Son J.	Front Microbiol	10.3389/fmicb.2018.00067	2018
Enzymology	Usefulness of a new mycobacteriophage-based technique for rapid diagnosis of pulmonary tuberculosis.	Alcaide F, Gali N, Dominguez J, Berlanga P, Blanco S, Orus P, Martin R.	J Clin Microbiol	10.1128/jcm.41.7.2867-2871.2003	2003
Phylogeny	Report of two fatal cases of Mycobacterium mucogenicum central nervous system infection in immunocompetent patients.	Adekambi T, Foucault C, La Scola B, Drancourt M	J Clin Microbiol	10.1128/JCM.44.3.837-840.2006	2006
Phylogeny	Dissection of phylogenetic relationships among 19 rapidly growing Mycobacterium species by 16S rRNA, hsp65, sodA, recA and rpoB gene sequencing.	Adekambi T, Drancourt M	Int J Syst Evol Microbiol	10.1099/ijs.0.63094-0	2004
Phylogeny	Seroreactive species-specific lipooligosaccharides of Mycobacterium mucogenicum sp. nov. (formerly Mycobacterium chelonae-like organisms): identification and chemical characterization.	Munoz M, Raynaud C, Laneelle MA, Julian E, Marin LML, Silve G, Ausina V, Daffe M, Luquin M	Microbiology (Reading)	10.1099/00221287-144-1-137	1998
Phylogeny	Phylogeny of the Mycobacterium chelonae-like organism based on partial sequencing of the 16S rRNA gene and proposal of Mycobacterium mucogenicum sp. nov.	Springer B, Bottger EC, Kirschner P, Wallace RJ Jr	Int J Syst Bacteriol	10.1099/00207713-45-2-262	1995

References

#11937	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 44625
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#36363	Collection of Institut Pasteur ; Curators of the CIP; CIP 105223
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68382	Automatically annotated from API zym .
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Mycobacterium mucogenicum (CIP 105223, DSM 44625, JCM 13575)

Name and taxonomic classification

Morphology

Cell morphology

Multimedia

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Metabolite utilization

Metabolite production

Enzymes

API zym

API biotype100

Isolation, sampling and environmental information

Isolation

Interaction and safety

Risk assessment

Sequence information

16S sequences

Genome-based predictions

Literature

Literature

References

BacDive

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