Actinomyces israelii (CIP 104730, CCUG 4867, NCTC 4860)

Name: Actinomyces israelii (CIP 104730, CCUG 4867, NCTC 4860)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 136339

Type strain

Culture col. no. CIP 104730 CCUG 4867 NCTC 4860

NCBI tax ID(s) 1659

Special Collections CCUG CIP

History CIP <- 1996, CCUG <- 1976, S.P. Lapage, NCTC <- 1935, L.P. Garrod, London, UK

Links

Actinomyces israelii CIP 104730 is an anaerobe, mesophilic prokaryote of the family Actinomycetaceae.

anaerobe mesophilic

Name and taxonomic classification

SI-ID 51235

CCUG 4867,CIP 104730,NCTC 4860

@ref 20215

Last LPSN update 2026-02-09 11:32:37

Domain Bacteria

Phylum Actinomycetota

Class Actinomycetes

Order Actinomycetales

Family Actinomycetaceae

Genus Actinomyces

Species Actinomyces israelii

Full scientific name Actinomyces israelii (Kruse 1896) Lachner-Sandoval 1898 (Approved Lists 1980)

Synonyms (2)

"Actinobacterium israeli"
"Streptothrix israeli"

BacDive ID	Other strains from **Actinomyces israelii** (36)	Type strain
151	A. israelii Jr 277 (CDC W855), DSM 43320, ATCC 12102, ... (type strain)
150	A. israelii CCUG 34702, DSM 43011, ATCC 10048, NHI 1829
152	A. israelii DSM 43323, WVU 339
105476	A. israelii STI09064(IMET), 1110-009,
105477	A. israelii STI09079(IMET), 1141-014,
135348	A. israelii B1, CIP 53.109
137141	A. israelii 1912, CIP 60.40
137277	A. israelii CIP 104876, NCTC 10236, CCUG 34502
138098	A. israelii CIP 104874, NCTC 6826, CCUG 34495
138099	A. israelii CCUG 34501, CIP 104875, NCTC 10215
141881	A. israelii CCUG 8060
146033	A. israelii CCUG 30217
147537	A. israelii CCUG 33763
147818	A. israelii CCUG 34284, ATCC 12597
147919	A. israelii CCUG 34496, NCTC 6827
147920	A. israelii CCUG 34497, NCTC 6830
147921	A. israelii CCUG 34498, NCTC 6831
147922	A. israelii CCUG 34499, NCTC 8047
147923	A. israelii CCUG 34500, NCTC 8439
147946	A. israelii CCUG 34556
147947	A. israelii CCUG 34557
148445	A. israelii CCUG 35455
148548	A. israelii CCUG 35624
148770	A. israelii CCUG 35922
148771	A. israelii CCUG 35923
148772	A. israelii CCUG 35924
148773	A. israelii CCUG 35925
148774	A. israelii CCUG 35926
149130	A. israelii CCUG 36904
149131	A. israelii CCUG 36905
149316	A. israelii CCUG 37486 C
149320	A. israelii CCUG 37496
152583	A. israelii CCUG 47135
154406	A. israelii CCUG 53438
154704	A. israelii CCUG 54890
156688	A. israelii CCUG 64147

Morphology

Colony morphology

44804

Incubation period2-3 days

Culture and growth conditions

Culture medium

@ref	Name	Growth	Composition	Medium link
35724	MEDIUM 39 - for Actinomyces		Distilled water make up to (1000.000 ml);Columbia agar (39.000 g);Horseblood (100.000 ml)
35724	CIP Medium 6			Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)	Range
35724	positive	growth	37	mesophilic
44804	positive	growth	37	mesophilic

Physiology and metabolism

Oxygen tolerance

44804

Oxygen toleranceanaerobe

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68381	40585 ChEBI	alpha-cyclodextrin	-	builds acid from	from API rID32STR
68381	29016 ChEBI	arginine	-	hydrolysis	from API rID32STR
68380	29016 ChEBI	arginine	-	hydrolysis	from API rID32A
68381	18333 ChEBI	D-arabitol	-	builds acid from	from API rID32STR
68377	15824 ChEBI	D-fructose	+	builds acid from	from API NH
68377	17634 ChEBI	D-glucose	+	builds acid from	from API NH
68381	16899 ChEBI	D-mannitol	-	builds acid from	from API rID32STR
68379	16899 ChEBI	D-mannitol	+	fermentation	from API Coryne
68380	16024 ChEBI	D-mannose	-	fermentation	from API rID32A
68381	16988 ChEBI	D-ribose	-	builds acid from	from API rID32STR
68379	16988 ChEBI	D-ribose	+	fermentation	from API Coryne
68381	16443 ChEBI	D-tagatose	-	builds acid from	from API rID32STR
68379	65327 ChEBI	D-xylose	+	fermentation	from API Coryne
68379	4853 ChEBI	esculin	+	hydrolysis	from API Coryne
68379	5291 ChEBI	gelatin	-	hydrolysis	from API Coryne
68381	28087 ChEBI	glycogen	-	builds acid from	from API rID32STR
68379	28087 ChEBI	glycogen	-	fermentation	from API Coryne
68381	606565 ChEBI	hippurate	-	hydrolysis	from API rID32STR
68381	30849 ChEBI	L-arabinose	-	builds acid from	from API rID32STR
68380	29985 ChEBI	L-glutamate	-	degradation	from API rID32A
68381	17716 ChEBI	lactose	-	builds acid from	from API rID32STR
68379	17716 ChEBI	lactose	+	fermentation	from API Coryne
68381	17306 ChEBI	maltose	-	builds acid from	from API rID32STR
68377	17306 ChEBI	maltose	+	builds acid from	from API NH
68379	17306 ChEBI	maltose	+	fermentation	from API Coryne
68381	6731 ChEBI	melezitose	-	builds acid from	from API rID32STR
68381	28053 ChEBI	melibiose	-	builds acid from	from API rID32STR
68381	320055 ChEBI	methyl beta-D-glucopyranoside	-	builds acid from	from API rID32STR
68379	17632 ChEBI	nitrate	-	reduction	from API Coryne
68380	17632 ChEBI	nitrate	-	reduction	from API rID32A
68377	18257 ChEBI	ornithine	-	degradation	from API NH
68381	27941 ChEBI	pullulan	-	builds acid from	from API rID32STR
68381	16634 ChEBI	raffinose	-	builds acid from	from API rID32STR
68380	16634 ChEBI	raffinose	-	fermentation	from API rID32A
68381	30911 ChEBI	sorbitol	-	builds acid from	from API rID32STR
68381	17992 ChEBI	sucrose	-	builds acid from	from API rID32STR
68379	17992 ChEBI	sucrose	+	fermentation	from API Coryne
68377	17992 ChEBI	sucrose	+	builds acid from	from API NH
68381	27082 ChEBI	trehalose	-	builds acid from	from API rID32STR
68377	27897 ChEBI	tryptophan	-	energy source	from API NH
68380	27897 ChEBI	tryptophan	-	energy source	from API rID32A
68381	16199 ChEBI	urea	-	hydrolysis	from API rID32STR
68379	16199 ChEBI	urea	-	hydrolysis	from API Coryne
68380	16199 ChEBI	urea	-	hydrolysis	from API rID32A
68377	16199 ChEBI	urea	-	hydrolysis	from API NH

Metabolite production

@ref	Chebi-ID	Metabolite
68381	15688 ChEBI	acetoin	from API rID32STR
68380	35581 ChEBI	indole	from API rID32A
68377	35581 ChEBI	indole	from API NH

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test	Indole test
68381	15688 ChEBI	acetoin	-		from API rID32STR
68380	35581 ChEBI	indole		-	from API rID32A
68377	35581 ChEBI	indole		-	from API NH

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	-	3.1.3.2	from API zym
68380	alanine arylamidase	-	3.4.11.2	from API rID32A
68381	Alanyl-Phenylalanyl-Proline arylamidase	-		from API rID32STR
68377	alkaline phosphatase	-	3.1.3.1	from API NH
68379	alkaline phosphatase	-	3.1.3.1	from API Coryne
68381	alkaline phosphatase	-	3.1.3.1	from API rID32STR
68380	alkaline phosphatase	-	3.1.3.1	from API rID32A
68382	alkaline phosphatase	-	3.1.3.1	from API zym
68380	alpha-arabinosidase	+	3.2.1.55	from API rID32A
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68380	alpha-fucosidase	-	3.2.1.51	from API rID32A
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68381	alpha-galactosidase	+	3.2.1.22	from API rID32STR
68380	alpha-galactosidase	+	3.2.1.22	from API rID32A
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68380	alpha-glucosidase	+	3.2.1.20	from API rID32A
68379	alpha-glucosidase	+	3.2.1.20	from API Coryne
68382	alpha-glucosidase	+	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68381	arginine dihydrolase	-	3.5.3.6	from API rID32STR
68380	arginine dihydrolase	-	3.5.3.6	from API rID32A
68381	beta-galactosidase	-	3.2.1.23	from API rID32STR
68379	beta-galactosidase	+	3.2.1.23	from API Coryne
68380	beta-galactosidase	+	3.2.1.23	from API rID32A
68377	beta-galactosidase	-	3.2.1.23	from API NH
68382	beta-galactosidase	-	3.2.1.23	from API zym
68380	beta-Galactosidase 6-phosphate	-		from API rID32A
68381	beta-glucosidase	+	3.2.1.21	from API rID32STR
68380	beta-glucosidase	+	3.2.1.21	from API rID32A
68379	beta-glucosidase	+	3.2.1.21	from API Coryne
68382	beta-glucosidase	+	3.2.1.21	from API zym
68381	beta-glucuronidase	-	3.2.1.31	from API rID32STR
68379	beta-glucuronidase	-	3.2.1.31	from API Coryne
68382	beta-glucuronidase	-	3.2.1.31	from API zym
68380	beta-glucuronidase	-	3.2.1.31	from API rID32A
68377	beta-lactamase	-	3.5.2.6	from API NH
68381	beta-mannosidase	-	3.2.1.25	from API rID32STR
68379	catalase	-	1.11.1.6	from API Coryne
68382	cystine arylamidase	-	3.4.11.3	from API zym
68382	esterase (C 4)	-		from API zym
68382	esterase lipase (C 8)	-		from API zym
68377	gamma-glutamyltransferase	-	2.3.2.2	from API NH
68379	gelatinase	-		from API Coryne
68380	glutamate decarboxylase	-	4.1.1.15	from API rID32A
68380	glutamyl-glutamate arylamidase	-		from API rID32A
68380	glycin arylamidase	-		from API rID32A
68381	glycyl tryptophan arylamidase	-		from API rID32STR
68380	histidine arylamidase	-		from API rID32A
68380	L-arginine arylamidase	-		from API rID32A
68380	leucine arylamidase	-	3.4.11.1	from API rID32A
68382	leucine arylamidase	+	3.4.11.1	from API zym
68380	leucyl glycin arylamidase	-	3.4.11.1	from API rID32A
68377	lipase	+		from API NH
68382	lipase (C 14)	-		from API zym
68381	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API rID32STR
68380	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API rID32A
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68379	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API Coryne
68382	naphthol-AS-BI-phosphohydrolase	-		from API zym
68377	ornithine decarboxylase	-	4.1.1.17	from API NH
68380	phenylalanine arylamidase	+		from API rID32A
68380	proline-arylamidase	-	3.4.11.5	from API rID32A
68377	proline-arylamidase	+	3.4.11.5	from API NH
68379	pyrazinamidase	-	3.5.1.B15	from API Coryne
68381	pyrrolidonyl arylamidase	-	3.4.19.3	from API rID32STR
68380	pyrrolidonyl arylamidase	-	3.4.19.3	from API rID32A
68379	pyrrolidonyl arylamidase	-	3.4.19.3	from API Coryne
68380	serine arylamidase	-		from API rID32A
68382	trypsin	-	3.4.21.4	from API zym
68377	tryptophan deaminase	-	4.1.99.1	from API NH
68380	tryptophan deaminase	-	4.1.99.1	from API rID32A
68380	tyrosine arylamidase	+		from API rID32A
68381	urease	-	3.5.1.5	from API rID32STR
68379	urease	-	3.5.1.5	from API Coryne
68380	urease	-	3.5.1.5	from API rID32A
68377	urease	-	3.5.1.5	from API NH
68382	valine arylamidase	-		from API zym

Fatty acid profile

Metadata FA analysis

@ref

44804

Fatty acid	Percentage	ECL
C16:0	49.6	16
C18:1 ω9c	26.2	17.769
C18:1 ω9c DMA	8.9	18.226
C18:0	7.2	18
C18:2 ω6,9c/C18:0 ANTE	5.3	17.724
C10:0	2.8	10

API coryne

@ref	Reduction of nitrateNIT	PYZ	PYRA	PAL	beta GUR	beta GAL	alpha GLU	beta NAG	ESC	URE	GEL	Control fermentationControl	GLU	RIB	XYL	MAN	MAL	LAC	SAC	GLYG	CAT
44804	-	-	-	-	-	+	+	-	+	-	-	-	not determinedn.d.	+	+	+	+	+	+	-	-

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
44804	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	+	+	-	-	-

API NH

@ref	PEN	GLU	FRU	MAL	SAC	ODC	URE	LIP	PAL	beta GAL	ProA	GGT	IND
44804	-	+	+	+	+	-	-	+	-	-	+	-	-

API rID32A

@ref	URE	ADH (Arg)	alpha GAL	beta GAL	beta-Galactosidase 6-phosphatebeta GP	alpha GLU	beta GLU	alpha ARA	beta GUR	beta-N-Acetyl-beta-glucosaminidasebeta NAG	MNE	RAF	GDC	alpha FUC	Reduction of nitrateNIT	IND	PAL	L-arginine arylamidaseArgA	ProA	LGA	Phenylalanine arylamidasePheA	Leucine arylamidaseLeuA	PyrA	Tyrosine arylamidaseTyrA	Alanine arylamidaseAlaA	Glycin arylamidaseGlyA	Histidine arylamidaseHisA	Glutamyl-glutamate arylamidaseGGA	Serine arylamidaseSerA
44804	-	-	+	+	-	+	+	+	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	+	-	-	-	-	-

API rID32STR

@ref	ADH (Arg)	beta GLU	beta GAR	beta GUR	alpha GAL	PAL	RIB	MAN	SOR	LAC	TRE	RAF	SAC	LARA	DARL	Acid from alpha-cyclodextrinCDEX	Acetoin production (Voges Proskauer test)VP	Alanyl-Phenylalanyl-Proline arylamidaseAPPA	beta GAL	Pyrrolidonyl arylamidasePyrA	N-Acetyl-glucosaminidasebeta NAG	Glycyl-tryptophan arylamidaseGTA	HIP	GLYG	PUL	MAL	MEL	MLZ	Acidification of methyl beta-D-glucopyranosideMbeta DG	TAG	beta MAN	URE
44804	-	+	-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-

Isolation, sampling and environmental information

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
35724	2	Risk group (French classification)

Sequence information

Genome-based predictions

Literature

Topic	Title	Authors	Journal	DOI	Year
Metabolism	Ability of oral bacteria to degrade fibronectin.	Wikstrom M, Linde A.	Infect Immun	10.1128/iai.51.2.707-711.1986	1986
Cultivation	Experience with a novel selective medium for isolation of Actinomyces spp. from medical and dental specimens.	Lewis R, McKenzie D, Bagg J, Dickie A.	J Clin Microbiol	10.1128/jcm.33.6.1613-1616.1995	1995
	SENSITIVITIES OF COLONIES AND SUSPENSIONS OF ACTINOMYCES ISRAELII TO PENICILLINS, TETRACYCLINES, AND ERYTHROMYCIN.	BLAKE GC.	Br Med J	10.1136/bmj.1.5376.145	1964
Phylogeny	Determination and analysis of Actinomyces israelii serotypes by fluorescent-antibody procedures.	Brock DW, Georg LK.	J Bacteriol	10.1128/jb.97.2.581-588.1969	1969
Phylogeny	Peptidoglycan types of bacterial cell walls and their taxonomic implications.	Schleifer KH, Kandler O.	Bacteriol Rev	10.1128/br.36.4.407-477.1972	1972

References

#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#35724	Collection of Institut Pasteur ; Curators of the CIP; CIP 104730
#44804	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 4867
#68377	Automatically annotated from API NH .
#68379	Automatically annotated from API Coryne .
#68380	Automatically annotated from API rID32A .
#68381	Automatically annotated from API rID32STR .
#68382	Automatically annotated from API zym .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Actinomyces israelii (CIP 104730, CCUG 4867, NCTC 4860)

Name and taxonomic classification