Clostridioides difficile W 1194 is an anaerobe, mesophilic, Gram-positive prokaryote of the family Peptostreptococcaceae.
Gram-positive rod-shaped anaerobe mesophilic| @ref 20215 |
Last LPSN update
2025-12-16 10:02:15 |
| Domain Bacillati |
| Phylum Bacillota |
| Class Clostridia |
| Order Peptostreptococcales |
| Family Peptostreptococcaceae |
| Genus Clostridioides |
| Species Clostridioides difficile |
| Full scientific name Clostridioides difficile (Hall and O'Toole 1935) Lawson et al. 2016 |
| Synonyms (3) |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68382 | acid phosphatase | - | 3.1.3.2 | from API zym |
| 68382 | alkaline phosphatase | - | 3.1.3.1 | from API zym |
| 68382 | alpha-chymotrypsin | - | 3.4.21.1 | from API zym |
| 68382 | alpha-fucosidase | - | 3.2.1.51 | from API zym |
| 68382 | alpha-galactosidase | - | 3.2.1.22 | from API zym |
| 68382 | alpha-glucosidase | - | 3.2.1.20 | from API zym |
| 68382 | alpha-mannosidase | - | 3.2.1.24 | from API zym |
| 68382 | beta-galactosidase | - | 3.2.1.23 | from API zym |
| 68382 | beta-glucosidase | - | 3.2.1.21 | from API zym |
| 68382 | beta-glucuronidase | - | 3.2.1.31 | from API zym |
| 34221 | catalase | - | 1.11.1.6 | |
| 68382 | cystine arylamidase | - | 3.4.11.3 | from API zym |
| 68382 | esterase (C 4) | + | from API zym | |
| 68382 | esterase lipase (C 8) | - | from API zym | |
| 68382 | leucine arylamidase | + | 3.4.11.1 | from API zym |
| 68382 | lipase (C 14) | - | from API zym | |
| 68382 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API zym |
| 68382 | naphthol-AS-BI-phosphohydrolase | - | from API zym | |
| 34221 | oxidase | - | ||
| 68382 | trypsin | - | 3.4.21.4 | from API zym |
| 34221 | urease | + | 3.5.1.5 | |
| 68382 | valine arylamidase | - | from API zym |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Pathogenicity | In Vitro Activity of Omadacycline and Five Comparators against Contemporary Ribotypes of Clostridioides difficile in Stockholm, Sweden. | Camporeale A, Tellapragada C, Kornijenko J, Nord CE, Giske CG. | Microbiol Spectr | 10.1128/spectrum.01440-21 | 2021 | |
| Prevalence of Non-Toxigenic Clostridioides difficile in Diarrhoea Patients and Their Clinical Characteristics. | Jeon CH, Kim SH, Wi YM. | Antibiotics (Basel) | 10.3390/antibiotics12091360 | 2023 | | |
| Metabolism | Truncation in the tcdC region of the Clostridium difficile PathLoc of clinical isolates does not predict increased biological activity of Toxin B or Toxin A. | Murray R, Boyd D, Levett PN, Mulvey MR, Alfa MJ. | BMC Infect Dis | 10.1186/1471-2334-9-103 | 2009 | |
| Phylogeny | Comparison of typing methods for Clostridium difficile isolates. | Wolfhagen MJ, Fluit AC, Torensma R, Jansze M, Kuypers AF, Verhage EA, Verhoef J. | J Clin Microbiol | 10.1128/jcm.31.8.2208-2211.1993 | 1993 | |
| Phylogeny | Comparison of PCR-ribotyping, arbitrarily primed PCR, and pulsed-field gel electrophoresis for typing Clostridium difficile. | Bidet P, Lalande V, Salauze B, Burghoffer B, Avesani V, Delmee M, Rossier A, Barbut F, Petit JC. | J Clin Microbiol | 10.1128/jcm.38.7.2484-2487.2000 | 2000 | |
| Effect of Lactobacillus acidophilus & epidermal growth factor on experimentally induced Clostridium difficile infection. | Kaur S, Vaishnavi C, Prasad KK, Ray P, Kochhar R. | Indian J Med Res | 2011 | | ||
| Activate to eradicate: inhibition of Clostridium difficile spore outgrowth by the synergistic effects of osmotic activation and nisin. | Nerandzic MM, Donskey CJ. | PLoS One | 10.1371/journal.pone.0054740 | 2013 | | |
| Phylogeny | Clostridium difficile genotyping based on slpA variable region in S-layer gene sequence: an alternative to serotyping. | Karjalainen T, Saumier N, Barc MC, Delmee M, Collignon A. | J Clin Microbiol | 10.1128/jcm.40.7.2452-2458.2002 | 2002 | |
| Phylogeny | Phenotypic and genotypic diversity of the flagellin gene (fliC) among Clostridium difficile isolates from different serogroups. | Tasteyre A, Karjalainen T, Avesani V, Delmee M, Collignon A, Bourlioux P, Barc MC. | J Clin Microbiol | 10.1128/jcm.38.9.3179-3186.2000 | 2000 | |
| Phylogeny | Typing of Clostridium difficile by western immunoblotting with 10 different antisera. | Kato H, Cavallaro JJ, Kato N, Bartley SL, Killgore GE, Watanabe K, Ueno K. | J Clin Microbiol | 10.1128/jcm.31.2.413-415.1993 | 1993 | |
| Rapid molecular characterization of Clostridium difficile and assessment of populations of C. difficile in stool specimens. | Wroblewski D, Hannett GE, Bopp DJ, Dumyati GK, Halse TA, Dumas NB, Musser KA. | J Clin Microbiol | 10.1128/jcm.02498-08 | 2009 | | |
| Pathogenicity | Bile salts and glycine as cogerminants for Clostridium difficile spores. | Sorg JA, Sonenshein AL. | J Bacteriol | 10.1128/jb.01765-07 | 2008 | |
| Metabolism | Molecular characterization of fliD gene encoding flagellar cap and its expression among Clostridium difficile isolates from different serogroups. | Tasteyre A, Karjalainen T, Avesani V, Delmee M, Collignon A, Bourlioux P, Barc MC. | J Clin Microbiol | 10.1128/jcm.39.3.1178-1183.2001 | 2001 | |
| Enzymology | Rapid detection of toxigenic Clostridium difficile in fecal samples by magnetic immuno PCR assay. | Wolfhagen MJ, Fluit AC, Torensma R, Poppelier MJ, Verhoef J. | J Clin Microbiol | 10.1128/jcm.32.7.1629-1633.1994 | 1994 | |
| Phylogeny | Use of an enzyme-linked immunoassay for Clostridium difficile serogrouping. | Delmee M, Depitre C, Corthier G, Ahoyo A, Avesani V. | J Clin Microbiol | 10.1128/jcm.31.9.2526-2528.1993 | 1993 | |
| Characterization of flagella of Clostridium difficile and their role in serogrouping reactions. | Delmee M, Avesani V, Delferriere N, Burtonboy G. | J Clin Microbiol | 10.1128/jcm.28.10.2210-2214.1990 | 1990 | | |
| Comparison of three enzyme immunoassays, a cytotoxicity assay, and toxigenic culture for diagnosis of Clostridium difficile-associated diarrhea. | Barbut F, Kajzer C, Planas N, Petit JC. | J Clin Microbiol | 10.1128/jcm.31.4.963-967.1993 | 1993 | | |
| Metabolism | Correlation of disease severity with fecal toxin levels in patients with Clostridium difficile-associated diarrhea and distribution of PCR ribotypes and toxin yields in vitro of corresponding isolates. | Akerlund T, Svenungsson B, Lagergren A, Burman LG. | J Clin Microbiol | 10.1128/jcm.44.2.353-358.2006 | 2006 | |
| Phylogeny | Epidemiology and molecular characterization of Clostridium difficile strains from patients with diarrhea: low disease incidence and evidence of limited cross-infection in a Swedish teaching hospital. | Svenungsson B, Burman LG, Jalakas-Pornull K, Lagergren A, Struwe J, Akerlund T. | J Clin Microbiol | 10.1128/jcm.41.9.4031-4037.2003 | 2003 | |
| Metabolism | Expression of Clostridium difficile toxins A and B and their sigma factor TcdD is controlled by temperature. | Karlsson S, Dupuy B, Mukherjee K, Norin E, Burman LG, Akerlund T. | Infect Immun | 10.1128/iai.71.4.1784-1793.2003 | 2003 | |
| Molecular epidemiology of hospital-associated and community-acquired Clostridium difficile infection in a Swedish county. | Noren T, Akerlund T, Back E, Sjoberg L, Persson I, Alriksson I, Burman LG. | J Clin Microbiol | 10.1128/jcm.42.8.3635-3643.2004 | 2004 | | |
| Physical map of the Clostridium difficile chromosome. | Norwood DA Jr, Sands JA | Gene | 10.1016/s0378-1119(97)00443-5 | 1997 | | |
| Exosporial membrane plasticity of Clostridium sporogenes and Clostridium difficile. | Panessa-Warren BJ, Tortora GT, Warren JB | Tissue Cell | 10.1016/s0040-8166(97)80031-6 | 1997 | | |
| Macrofragment localization of the toxin A and toxin B genes of Clostridium difficile. | Norwood DA Jr, Sands JA | Clin Diagn Lab Immunol | 10.1128/cdli.3.6.782-785.1996 | 1996 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive135237.20251217.10
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BacDive in 2025: the core database for prokaryotic strain data
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