Shigella flexneri (CIP 106171, 14, M52)

Name: Shigella flexneri (CIP 106171, 14, M52)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 134549

Type strain

Strain Designation 14, M52

Culture col. no. CIP 106171 14 M52

NCBI tax ID(s) 623

Special Collections CIP

History CIP <- 1999, D. Mazel, Inst. Pasteur, Paris, France <- N. Datta: strain 14 <- Murray: strain M52

Links

Shigella flexneri 14 is a facultative anaerobe, Gram-negative, rod-shaped bacterium of the family Enterobacteriaceae.

Gram-negative rod-shaped facultative anaerobe Bacteria

Name and taxonomic classification

SI-ID 70173

CIP 106171

@ref 20215

Last LPSN update 2026-02-09 11:32:13

Domain Bacteria

Phylum Pseudomonadota

Class Gammaproteobacteria

Order Enterobacterales

Family Enterobacteriaceae

Genus Shigella

Species Shigella flexneri

Full scientific name Shigella flexneri Castellani and Chalmers 1919 (Approved Lists 1980)

BacDive ID	Other strains from **Shigella flexneri** (47)	Type strain
5171	S. flexneri 24570, DSM 4782, ATCC 29903, KCTC 22192, ... (type strain)
134486	S. flexneri Boyd 88, CIP 54.41
134492	S. flexneri Trebuchon, CIP 55.19
134551	S. flexneri 42, M184, CIP 106199
134806	S. flexneri Bagdad 30/66, CIP 67.61
134963	S. flexneri 112540, CIP 107169
135204	S. flexneri 52, M231, CIP 106209
135205	S. flexneri M232, 53, CIP 106210
135206	S. flexneri 54, CIP 106211
135583	S. flexneri 52261, CIP 56.13
135925	S. flexneri 45, M195, CIP 106202, NCTC 3083
135970	S. flexneri Boyd 203, CIP 52.37
135971	S. flexneri Mulatta 103 Z, CIP 52.43, NCTC 8336
136212	S. flexneri 53125, CIP 53.3
136461	S. flexneri 935, CIP 54.58
137152	S. flexneri 24 D, CIP 52.36
137186	S. flexneri Ratcliffe, CIP 52.24
137190	S. flexneri CIP 52.46
137262	S. flexneri 3591-52, CCUG 32079, CIP 104222, ATCC 12022, ...
137306	S. flexneri Z Withington, CIP 54.40, NCTC 7
138629	S. flexneri 26 D, CIP 52.38
138828	S. flexneri 164, CIP 56.19
139147	S. flexneri Ledingham, CIP 52.35
139151	S. flexneri Boyd 102, CIP 52.40
139153	S. flexneri 145-48, CIP 52.44
139198	S. flexneri Zaboli, CIP 52.25, CIP 52.47
139289	S. flexneri 7, M32, CIP 106164
139295	S. flexneri 44, M190, CIP 106201
139301	S. flexneri M148, 30, CIP 106187
139304	S. flexneri 92, CIP 106192
139305	S. flexneri 36, M174, CIP 106193
139309	S. flexneri M181, 40, CIP 106197
139327	S. flexneri 80, CIP 106236
139471	S. flexneri 2457T, CIP 107659, ATCC 700930
141993	S. flexneri CCUG 9566, NCTC 1
143797	S. flexneri CCUG 21251
143807	S. flexneri CCUG 21270
145724	S. flexneri CCUG 29412
145725	S. flexneri CCUG 29413
145727	S. flexneri CCUG 29415
145728	S. flexneri CCUG 29416
149518	S. flexneri CCUG 37890
149526	S. flexneri CCUG 37906
150071	S. flexneri CCUG 38947
150141	S. flexneri CCUG 39080
151363	S. flexneri CCUG 43875
155003	S. flexneri CCUG 56027

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Motility
32946	negative	rod-shaped

Culture and growth conditions

Culture medium

@ref	Name	Composition	Medium link
32946	MEDIUM 3 - Columbia agar	Columbia agar (39.000 g);distilled water (1000.000 ml)
32946	CIP Medium 3		Medium recipe at CIP
32946	CIP Medium 72		Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)
32946	positive	growth	30
32946	positive	growth	30-41
32946	negative	growth	5
32946	negative	growth	10

Physiology and metabolism

Oxygen tolerance

32946

Oxygen tolerancefacultative anaerobe

Spore formation

32946

Spore formationno

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
32946	16947 ChEBI	citrate	-	carbon source
32946	17234 ChEBI	glucose	+	fermentation
32946	17234 ChEBI	glucose	+	degradation
32946	17716 ChEBI	lactose	-	fermentation
32946	15792 ChEBI	malonate	-	assimilation
32946	29864 ChEBI	mannitol	+	fermentation
32946	17632 ChEBI	nitrate	+	reduction
32946	16301 ChEBI	nitrite	+	reduction
32946	132112 ChEBI	sodium thiosulfate	-	builds gas from

Antibiotic resistance

@ref	Metabolite	Is sensitive	Is resistant
32946	0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate)

Metabolite production

@ref	Chebi-ID	Metabolite	Production
32946	35581 ChEBI	indole

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test	Methylred-test
32946	15688 ChEBI	acetoin	-
32946	17234 ChEBI	glucose		+

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
32946	alcohol dehydrogenase	-	1.1.1.1
68382	alkaline phosphatase	+	3.1.3.1	from API zym
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68382	alpha-glucosidase	+	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68382	beta-galactosidase	-	3.2.1.23	from API zym
32946	beta-galactosidase	-	3.2.1.23
68382	beta-glucosidase	-	3.2.1.21	from API zym
68382	beta-glucuronidase	-	3.2.1.31	from API zym
32946	catalase	+	1.11.1.6
68382	cystine arylamidase	-	3.4.11.3	from API zym
68382	esterase (C 4)	-		from API zym
68382	esterase lipase (C 8)	-		from API zym
32946	gelatinase	-
68382	leucine arylamidase	+	3.4.11.1	from API zym
68382	lipase (C 14)	-		from API zym
32946	lysine decarboxylase	-	4.1.1.18
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
32946	ornithine decarboxylase	-	4.1.1.17
32946	oxidase	-
32946	phenylalanine ammonia-lyase	-	4.3.1.24
68382	trypsin	+	3.4.21.4	from API zym
32946	tryptophan deaminase	-
32946	urease	-	3.5.1.5
68382	valine arylamidase	+		from API zym

Pathway annotation

Computationally determined by

@ref	pathway	enzyme coverage	annotated reactions
66794	L-lactaldehyde degradation	100	3 of 3
66794	coenzyme A metabolism	100	4 of 4
66794	anapleurotic synthesis of oxalacetate	100	1 of 1
66794	aerobactin biosynthesis	100	1 of 1
66794	4-hydroxyphenylacetate degradation	100	10 of 10
66794	ppGpp biosynthesis	100	4 of 4
66794	methylglyoxal degradation	100	5 of 5
66794	taurine degradation	100	1 of 1
66794	adipate degradation	100	2 of 2
66794	suberin monomers biosynthesis	100	2 of 2
66794	CDP-diacylglycerol biosynthesis	100	2 of 2
66794	UDP-GlcNAc biosynthesis	100	3 of 3
66794	starch degradation	100	10 of 10
66794	biotin biosynthesis	100	4 of 4
66794	sulfopterin metabolism	100	4 of 4
66794	formaldehyde oxidation	100	3 of 3
66794	acetate fermentation	100	4 of 4
66794	enterobactin biosynthesis	100	3 of 3
66794	tetrahydrofolate metabolism	100	14 of 14
66794	folate polyglutamylation	100	1 of 1
66794	ubiquinone biosynthesis	100	7 of 7
66794	sulfoquinovose degradation	100	3 of 3
66794	gluconeogenesis	100	8 of 8
66794	vitamin K metabolism	100	5 of 5
66794	palmitate biosynthesis	95.45	21 of 22
66794	NAD metabolism	94.44	17 of 18
66794	heme metabolism	92.86	13 of 14
66794	glutathione metabolism	92.86	13 of 14
66794	photosynthesis	92.86	13 of 14
66794	vitamin B6 metabolism	90.91	10 of 11
66794	pentose phosphate pathway	90.91	10 of 11
66794	Entner Doudoroff pathway	90	9 of 10
66794	threonine metabolism	90	9 of 10
66794	valine metabolism	88.89	8 of 9
66794	serine metabolism	88.89	8 of 9
66794	lipid A biosynthesis	88.89	8 of 9
66794	chorismate metabolism	88.89	8 of 9
66794	molybdenum cofactor biosynthesis	88.89	8 of 9
66794	C4 and CAM-carbon fixation	87.5	7 of 8
66794	degradation of sugar alcohols	87.5	14 of 16
66794	isoleucine metabolism	87.5	7 of 8
66794	reductive acetyl coenzyme A pathway	85.71	6 of 7
66794	vitamin B1 metabolism	84.62	11 of 13
66794	glycolate and glyoxylate degradation	83.33	5 of 6
66794	purine metabolism	82.98	78 of 94
66794	gallate degradation	80	4 of 5
66794	peptidoglycan biosynthesis	80	12 of 15
66794	glycogen metabolism	80	4 of 5
66794	metabolism of amino sugars and derivatives	80	4 of 5
66794	pyrimidine metabolism	80	36 of 45
66794	alanine metabolism	79.31	23 of 29
66794	glutamate and glutamine metabolism	78.57	22 of 28
66794	citric acid cycle	78.57	11 of 14
66794	aspartate and asparagine metabolism	77.78	7 of 9
66794	d-mannose degradation	77.78	7 of 9
66794	phenylalanine metabolism	76.92	10 of 13
66794	urea cycle	76.92	10 of 13
66794	glycogen biosynthesis	75	3 of 4
66794	lactate fermentation	75	3 of 4
66794	dTDPLrhamnose biosynthesis	75	6 of 8
66794	CMP-KDO biosynthesis	75	3 of 4
66794	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	75	6 of 8
66794	flavin biosynthesis	73.33	11 of 15
66794	oxidative phosphorylation	72.53	66 of 91
66794	degradation of sugar acids	72	18 of 25
66794	cardiolipin biosynthesis	71.43	5 of 7
66794	lipid metabolism	70.97	22 of 31
66794	glycolysis	70.59	12 of 17
66794	leucine metabolism	69.23	9 of 13
66794	non-pathway related	68.42	26 of 38
66794	degradation of pentoses	67.86	19 of 28
66794	allantoin degradation	66.67	6 of 9
66794	CO2 fixation in Crenarchaeota	66.67	6 of 9
66794	cyanate degradation	66.67	2 of 3
66794	octane oxidation	66.67	2 of 3
66794	selenocysteine biosynthesis	66.67	4 of 6
66794	methane metabolism	66.67	2 of 3
66794	acetoin degradation	66.67	2 of 3
66794	tryptophan metabolism	65.79	25 of 38
66794	isoprenoid biosynthesis	65.38	17 of 26
66794	proline metabolism	63.64	7 of 11
66794	ketogluconate metabolism	62.5	5 of 8
66794	methionine metabolism	61.54	16 of 26
66794	degradation of hexoses	61.11	11 of 18
66794	hydrogen production	60	3 of 5
66794	lipoate biosynthesis	60	3 of 5
66794	propanol degradation	57.14	4 of 7
66794	cysteine metabolism	55.56	10 of 18
66794	nitrate assimilation	55.56	5 of 9
66794	phenol degradation	55	11 of 20
66794	arginine metabolism	54.17	13 of 24
66794	sulfate reduction	53.85	7 of 13
66794	3-phenylpropionate degradation	53.33	8 of 15
66794	lysine metabolism	52.38	22 of 42
66794	histidine metabolism	51.72	15 of 29
66794	carnitine metabolism	50	4 of 8
66794	myo-inositol biosynthesis	50	5 of 10
66794	toluene degradation	50	2 of 4
66794	pantothenate biosynthesis	50	3 of 6
66794	ribulose monophosphate pathway	50	1 of 2
66794	propionate fermentation	50	5 of 10
66794	quinate degradation	50	1 of 2
66794	butanoate fermentation	50	2 of 4
66794	ethanol fermentation	50	1 of 2
66794	cis-vaccenate biosynthesis	50	1 of 2
66794	tyrosine metabolism	50	7 of 14
66794	polyamine pathway	47.83	11 of 23
66794	ascorbate metabolism	45.45	10 of 22
66794	d-xylose degradation	45.45	5 of 11
66794	metabolism of disaccharids	45.45	5 of 11
66794	degradation of aromatic, nitrogen containing compounds	41.67	5 of 12
66794	ethylmalonyl-CoA pathway	40	2 of 5
66794	coenzyme M biosynthesis	40	4 of 10
66794	glycine metabolism	40	4 of 10
66794	3-chlorocatechol degradation	40	2 of 5
66794	phosphatidylethanolamine bioynthesis	38.46	5 of 13
66794	phenylpropanoid biosynthesis	38.46	5 of 13
66794	acetyl CoA biosynthesis	33.33	1 of 3
66794	IAA biosynthesis	33.33	1 of 3
66794	methanogenesis from CO2	33.33	4 of 12
66794	sphingosine metabolism	33.33	2 of 6
66794	vitamin B12 metabolism	32.35	11 of 34
66794	androgen and estrogen metabolism	31.25	5 of 16
66794	arachidonic acid metabolism	27.78	5 of 18
66794	cyclohexanol degradation	25	1 of 4

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
32946	-	+	-	-	-	+	+	-	+	-	+	+	-	-	-	+	-	-	-	-

API biotype100

@ref	ControlQ	D-glucose as carbon sourceGLU	D-fructose as carbon sourceFRU	D-galactose as carbon sourceGAL	D-trehalose as carbon sourceTRE	D-mannose as carbon sourceMNE	L-sorbose as carbon sourceSBE	D-melibiose as carbon sourceMEL	sucrose as carbon sourceSAC	D-raffinose as carbon sourceRAF	maltotriose as carbon sourceMTE	maltose as carbon sourceMAL	lactose as carbon sourceLAC	lactulose as carbon sourceLTE	1-O-methyl-beta-galactopyranoside as carbon sourceMbGa	1-O-methyl-alpha-galactopyranoside as carbon sourceMaGa	D-cellobiose as carbon sourceCEL	gentiobiose as carbon sourceGEN	1-O-methyl-beta-D-glucopyranoside as carbon sourceMbGu	esculin as carbon sourceESC	D-ribose as carbon sourceRIB	L-arabinose as carbon sourceARA	D-xylose as carbon sourceXYL	palatinose as carbon sourcePLE	L-rhamnose as carbon sourceRHA	L-fucose as carbon sourceFUC	D-melezitose as carbon sourceMLZ	D-arabitol as carbon sourceDARL	L-arabitol as carbon sourceLARL	xylitol as carbon sourceXLT	dulcitol as carbon sourceDUL	D-tagatose as carbon sourceTAG	glycerol as carbon sourceGLY	myo-inositol as carbon sourceINO	D-mannitol as carbon sourceMAN	maltitol as carbon sourceMTL	D-turanose as carbon sourceTUR	D-sorbitol as carbon sourceSOR	adonitol as carbon sourceADO	hydroxyquinoline-beta-glucuronide as carbon sourceHBG	D-lyxose as carbon sourceLYX	i-erythritol as carbon sourceERY	1-O-methyl-alpha-D-glucoside as carbon sourceMDG	3-O-methyl-D-glucose as carbon source3MDG	D-saccharate as carbon sourceSAT	mucate as carbon sourceMUC	L-tartrate as carbon sourceLTAT	D-tartrate as carbon sourceDTAT	meso-tartrate as carbon sourceMTAT	D-malate as carbon sourceDMLT	L-malate as carbon sourceLMLT	cis-aconitate as carbon sourceCATE	trans-aconitate as carbon sourceTATE	tricarballylate as carbon sourceTTE	citrate as carbon sourceCIT	D-glucuronate as carbon sourceGRT	D-galacturonate as carbon sourceGAT	2-ketogluconate as carbon source2KG	5-ketogluconate as carbon source5KG	tryptophan as carbon sourceTRY	N-acetyl-D-glucosamine as carbon sourceNAG	D-gluconate as carbon sourceGNT	phenylacetate as carbon sourcePAC	protocatechuate as carbon sourcePAT	4-hydroxybenzoate as carbon sourcepOBE	quinate as carbon sourceQAT	gentisate as carbon sourceGTE	3-hydroxybenzoate as carbon sourcemOBE	benzoate as carbon sourceBAT	3-phenylpropionate as carbon sourcePPAT	m-coumarate as carbon sourceCMT	trigonelline as carbon sourceTGE	betaine as carbon sourceBET	putrescine as carbon sourcePCE	4-aminobutyrate as carbon sourceABT	histamine as carbon sourceHIN	DL-lactate as carbon sourceLAT	caprate as carbon sourceCAP	caprylate as carbon sourceCYT	L-histidine as carbon sourceHIS	succinate as carbon sourceSUC	fumarate as carbon sourceFUM	glutarate as carbon sourceGRE	DL-glycerate as carbon sourceGYT	5-aminovalerate as carbon sourceAVT	ethanolamine as carbon sourceETN	tryptamine as carbon sourceTTN	D-glucosamine as carbon sourceGLN	itaconate as carbon sourceITA	3-hydroxybutyrate as carbon source3OBU	L-aspartate as carbon sourceAPT	L-glutamate as carbon sourceGTT	L-proline as carbon sourcePRO	D-alanine as carbon sourceDALA	L-alanine as carbon sourceLALA	L-serine as carbon sourceSER	malonate as carbon sourceMNT	propionate as carbon sourcePROP	L-tyrosine as carbon sourceTYR	2-ketoglutarate as carbon source2KT
32946	not determinedn.d.	+	+	+	+	+	-	+	-	+	+	+	-	-	-	+	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	+	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	-	+	+	-	-	-	+	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	+	+	-	-	-	-	-	+	-	-	+	-	-	-	+	-	-	-	-	-

Isolation, sampling and environmental information

Isolation

32946

Isolation date1918

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
32946	2	Risk group (French classification)

Sequence information

Genome-based predictions

Literature

Topic	Title	Authors	Journal	DOI	Year
Phylogeny	Selection and validation of a multilocus variable-number tandem-repeat analysis panel for typing Shigella spp.	Gorge O, Lopez S, Hilaire V, Lisanti O, Ramisse V, Vergnaud G.	J Clin Microbiol	10.1128/jcm.02027-07	2008

References

#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#32946	Collection of Institut Pasteur ; Curators of the CIP; CIP 106171
#66794	Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg: BRENDA, the ELIXIR core data resource in 2021: new developments and updates. Nucleic Acids Res. 49: D498 - D508 2020 ( DOI 10.1093/nar/gkaa1025 , PubMed 33211880 )
#68382	Automatically annotated from API zym .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Shigella flexneri (CIP 106171, 14, M52)

Name and taxonomic classification

Morphology

Cell morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Spore formation

Metabolite utilization

Antibiotic resistance

Metabolite production

Metabolite tests

Enzymes

Pathway annotation

API zym

API biotype100

Isolation, sampling and environmental information

Isolation

Interaction and safety

Risk assessment

Sequence information

Genome-based predictions

Literature

Literature

References

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