Name: Helicobacter hepaticus CIP 104102
Creator: BacDive
License: http://creativecommons.org/licenses/by-nc/4.0/

Strain identifier

BacDive ID: 134450

Type strain:

Species: Helicobacter hepaticus

Culture col. no.: CIP 104102, ATCC 51449, CCUG 44777

NCBI tax ID(s): 235279 (strain), 32025 (species)

Other strains from Helicobacter hepaticus

H. hepaticus Hh-2, DSM 22909, ATCC 51448, CCUG ... (type strain)
H. hepaticus CIP 104101, ATCC 51450, CCUG 44776
H. hepaticus CCUG 34904, NCTC 12886

Section

Helicobacter hepaticus CIP 104102 is a mesophilic bacterium of the family Helicobacteraceae.

mesophilic
Bacteria
genome sequence

Information on the name and the taxonomic classification. Name and taxonomic classification

	Last LPSN update	07-12-2022 (DD-MM-YYYY)
	Domain	"Bacteria"
	Phylum	*Pseudomonadota*
	Class	*Epsilonproteobacteria*
	Order	*Campylobacterales*
	Family	*Helicobacteraceae*
	Genus	*Helicobacter*
	Species	**Helicobacter hepaticus**
	Full Scientific Name (PNU)	Helicobacter hepaticus Fox et al. 1994

Synonym

"Helicobacter hepaticus"

Information on culture and growth conditions Culture and growth conditions

[Ref.: #32776]

Culture medium

MEDIUM 6 - Columbia agar with 10 % horse blood

[Ref.: #32776]

Culture medium growth

[Ref.: #32776]

Culture medium composition

expand / minimize

	Temperatures	Kind of temperature		Temperature
[Ref.: #32776]			growth	37 °C

[Ref.: #32776]

Temperature range

mesophilic

Information on physiology and metabolism Physiology and metabolism

	Pathway	Enzyme coverage	Annotated reactions
	Pathway annotation	Computationally determined by
[Ref.: #66794]	suberin monomers biosynthesis	100	2 of 2
[Ref.: #66794]	coenzyme A metabolism	100	4 of 4
[Ref.: #66794]	kanosamine biosynthesis II	100	2 of 2
[Ref.: #66794]	CDP-diacylglycerol biosynthesis	100	2 of 2
[Ref.: #66794]	biotin biosynthesis	100	4 of 4
[Ref.: #66794]	UDP-GlcNAc biosynthesis	100	3 of 3
[Ref.: #66794]	reductive acetyl coenzyme A pathway	100	7 of 7
[Ref.: #66794]	folate polyglutamylation	100	1 of 1
[Ref.: #66794]	anapleurotic synthesis of oxalacetate	100	1 of 1
[Ref.: #66794]	ppGpp biosynthesis	100	4 of 4
[Ref.: #66794]	palmitate biosynthesis	95.45	21 of 22
[Ref.: #66794]	chorismate metabolism	88.89	8 of 9
[Ref.: #66794]	lipid A biosynthesis	88.89	8 of 9
[Ref.: #66794]	ubiquinone biosynthesis	85.71	6 of 7
[Ref.: #66794]	photosynthesis	85.71	12 of 14
[Ref.: #66794]	tetrahydrofolate metabolism	85.71	12 of 14
[Ref.: #66794]	1,4-dihydroxy-6-naphthoate biosynthesis	83.33	5 of 6
[Ref.: #66794]	peptidoglycan biosynthesis	80	12 of 15
[Ref.: #66794]	methylglyoxal degradation	80	4 of 5
[Ref.: #66794]	threonine metabolism	80	8 of 10
[Ref.: #66794]	molybdenum cofactor biosynthesis	77.78	7 of 9
[Ref.: #66794]	valine metabolism	77.78	7 of 9
[Ref.: #66794]	d-mannose degradation	77.78	7 of 9
[Ref.: #66794]	NAD metabolism	77.78	14 of 18
[Ref.: #66794]	CMP-KDO biosynthesis	75	3 of 4
[Ref.: #66794]	isoleucine metabolism	75	6 of 8
[Ref.: #66794]	acetate fermentation	75	3 of 4
[Ref.: #66794]	proline metabolism	72.73	8 of 11
[Ref.: #66794]	cardiolipin biosynthesis	71.43	5 of 7
[Ref.: #66794]	propionate fermentation	70	7 of 10
[Ref.: #66794]	vitamin B1 metabolism	69.23	9 of 13
[Ref.: #66794]	alanine metabolism	68.97	20 of 29
[Ref.: #66794]	glutamate and glutamine metabolism	67.86	19 of 28
[Ref.: #66794]	aspartate and asparagine metabolism	66.67	6 of 9
[Ref.: #66794]	flavin biosynthesis	66.67	10 of 15
[Ref.: #66794]	formaldehyde oxidation	66.67	2 of 3
[Ref.: #66794]	serine metabolism	66.67	6 of 9
[Ref.: #66794]	acetoin degradation	66.67	2 of 3
[Ref.: #66794]	selenocysteine biosynthesis	66.67	4 of 6
[Ref.: #66794]	isoprenoid biosynthesis	65.38	17 of 26
[Ref.: #66794]	C4 and CAM-carbon fixation	62.5	5 of 8
[Ref.: #66794]	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	62.5	5 of 8
[Ref.: #66794]	gluconeogenesis	62.5	5 of 8
[Ref.: #66794]	methionine metabolism	61.54	16 of 26
[Ref.: #66794]	phenylalanine metabolism	61.54	8 of 13
[Ref.: #66794]	hydrogen production	60	3 of 5
[Ref.: #66794]	citric acid cycle	57.14	8 of 14
[Ref.: #66794]	propanol degradation	57.14	4 of 7
[Ref.: #66794]	heme metabolism	57.14	8 of 14
[Ref.: #66794]	polyamine pathway	56.52	13 of 23
[Ref.: #66794]	cysteine metabolism	55.56	10 of 18
[Ref.: #66794]	non-pathway related	55.26	21 of 38
[Ref.: #66794]	leucine metabolism	53.85	7 of 13
[Ref.: #66794]	urea cycle	53.85	7 of 13
[Ref.: #66794]	purine metabolism	52.13	49 of 94
[Ref.: #66794]	ethanol fermentation	50	1 of 2
[Ref.: #66794]	sulfopterin metabolism	50	2 of 4
[Ref.: #66794]	glycogen biosynthesis	50	2 of 4
[Ref.: #66794]	cis-vaccenate biosynthesis	50	1 of 2
[Ref.: #66794]	butanoate fermentation	50	2 of 4
[Ref.: #66794]	arginine metabolism	50	12 of 24
[Ref.: #66794]	ketogluconate metabolism	50	4 of 8
[Ref.: #66794]	adipate degradation	50	1 of 2
[Ref.: #66794]	glycolate and glyoxylate degradation	50	3 of 6
[Ref.: #66794]	histidine metabolism	48.28	14 of 29
[Ref.: #66794]	lysine metabolism	47.62	20 of 42
[Ref.: #66794]	pyrimidine metabolism	46.67	21 of 45
[Ref.: #66794]	vitamin B6 metabolism	45.45	5 of 11
[Ref.: #66794]	oxidative phosphorylation	45.05	41 of 91
[Ref.: #66794]	tryptophan metabolism	44.74	17 of 38
[Ref.: #66794]	nitrate assimilation	44.44	4 of 9
[Ref.: #66794]	CO2 fixation in Crenarchaeota	44.44	4 of 9
[Ref.: #66794]	tyrosine metabolism	42.86	6 of 14
[Ref.: #66794]	glutathione metabolism	42.86	6 of 14
[Ref.: #66794]	degradation of aromatic, nitrogen containing compounds	41.67	5 of 12
[Ref.: #66794]	glycolysis	41.18	7 of 17
[Ref.: #66794]	coenzyme M biosynthesis	40	4 of 10
[Ref.: #66794]	Entner Doudoroff pathway	40	4 of 10
[Ref.: #66794]	starch degradation	40	4 of 10
[Ref.: #66794]	glycine metabolism	40	4 of 10
[Ref.: #66794]	metabolism of amino sugars and derivatives	40	2 of 5
[Ref.: #66794]	sulfate reduction	38.46	5 of 13
[Ref.: #66794]	dTDPLrhamnose biosynthesis	37.5	3 of 8
[Ref.: #66794]	pentose phosphate pathway	36.36	4 of 11
[Ref.: #66794]	lipid metabolism	35.48	11 of 31
[Ref.: #66794]	octane oxidation	33.33	1 of 3
[Ref.: #66794]	IAA biosynthesis	33.33	1 of 3
[Ref.: #66794]	cyanate degradation	33.33	1 of 3
[Ref.: #66794]	pantothenate biosynthesis	33.33	2 of 6
[Ref.: #66794]	(5R)-carbapenem carboxylate biosynthesis	33.33	1 of 3
[Ref.: #66794]	L-lactaldehyde degradation	33.33	1 of 3
[Ref.: #66794]	degradation of hexoses	33.33	6 of 18
[Ref.: #66794]	enterobactin biosynthesis	33.33	1 of 3
[Ref.: #66794]	phenylpropanoid biosynthesis	30.77	4 of 13
[Ref.: #66794]	carotenoid biosynthesis	27.27	6 of 22
[Ref.: #66794]	d-xylose degradation	27.27	3 of 11
[Ref.: #66794]	toluene degradation	25	1 of 4
[Ref.: #66794]	lactate fermentation	25	1 of 4
[Ref.: #66794]	vitamin E metabolism	25	1 of 4
[Ref.: #66794]	degradation of sugar alcohols	25	4 of 16
		Only first 10 entries are displayed. Click here to see all.

Information on isolation source, the sampling and environmental conditions Isolation, sampling and environmental information

[Ref.: #56478]	Sample type/isolated from	Mouse liver
[Ref.: #56478]	Sampling date	1993
[Ref.: #56478]	Geographic location (country and/or sea, region)	Frederik
[Ref.: #56478]	Country	USA
[Ref.: #56478]	Country ISO 3 Code	USA
[Ref.: #56478]	Continent	North America

[Ref.: #32776]	Geographic location (country and/or sea, region)	Frederik, MD
[Ref.: #32776]	Country	USA
[Ref.: #32776]	Country ISO 3 Code	USA
[Ref.: #32776]	Continent	North America
* marker position based on {}

Isolation sources categories

#Host Body-Site	#Organ	#Liver
#Host	#Mammals	#Muridae (Mouse/Rat)

What are isolation sources categories?

Information on genomic background e.g. entries in nucleic sequence databass Sequence information

Genome sequence information:

	Sequence accession description	Seq. accession number	Assembly level (bp)	Sequence database	Associated NCBI tax ID
[Ref.: #66792]	Helicobacter hepaticus ATCC 51449 ATCC 51449	GCA_000007905	complete	GenBank	235279 tax ID	*
[Ref.: #66792]	Helicobacter hepaticus ATCC 51449	235279.5	complete	PATRIC	235279 tax ID	*
[Ref.: #66792]	Helicobacter hepaticus 3B1, ATCC 51449	637000131	complete	JGI IMG/M	235279 tax ID	*
[Ref.: #66792]	Vibrio cholerae DL4213	GCA_017426985	contig	PATRIC	666 tax ID	*

Availability in culture collections External links

[Ref.: #32776]

Culture collection no.

CIP 104102, ATCC 51449, CCUG 44777

[Ref.: #20218]

Associated Passport(s) in StrainInfo

151660, 45564

Literature:

Only first 10 entries are displayed. Click here to see all.

Topic	Title	Authors	Journal	DOI	Year
Genetics	The complete genome sequence of the carcinogenic bacterium Helicobacter hepaticus.	Suerbaum S, Josenhans C, Sterzenbach T, Drescher B, Brandt P, Bell M, Droge M, Fartmann B, Fischer HP, Ge Z, Horster A, Holland R, Klein K, Konig J, Macko L, Mendz GL, Nyakatura G, Schauer DB, Shen Z, Weber J, Frosch M, Fox JG	Proc Natl Acad Sci U S A	10.1073/pnas.1332093100	2003	*
Genetics	Different Helicobacter hepaticus strains with variable genomic content induce various degrees of hepatitis.	Boutin SR, Shen Z, Rogers AB, Feng Y, Ge Z, Xu S, Sterzenbach T, Josenhans C, Schauer DB, Suerbaum S, Fox JG	Infect Immun	10.1128/IAI.73.12.8449-8452.2005	2005	*
Enzymology	Differential regulation of urease activity in Helicobacter hepaticus and Helicobacter pylori.	Belzer C, Stoof J, Beckwith CS, Kuipers EJ, Kusters JG, van Vliet AHM	Microbiology (Reading)	10.1099/mic.0.28188-0	2005	*
Metabolism	Iron-responsive repression of urease expression in Helicobacter hepaticus is mediated by the transcriptional regulator Fur.	Belzer C, van Schendel BA, Kuipers EJ, Kusters JG, van Vliet AH	Infect Immun	10.1128/IAI.01163-06	2006	*
Enzymology	The NADPH quinone reductase MdaB confers oxidative stress resistance to Helicobacter hepaticus.	Hong Y, Wang G, Maier RJ	Microb Pathog	10.1016/j.micpath.2006.08.005	2007	*
Enzymology	[Cloning and bioinformatics analysis of recombinant methyl-accepting chemotaxis signal transduction protein of Helicobacter hepaticus].	Niu LY, Bai Y, Guo Z, Xia GS, Li J, Qin HP, Wang JD	Nan Fang Yi Ke Da Xue Xue Bao		2009	*
	Lactobacillus reuteri promotes Helicobacter hepaticus-associated typhlocolitis in gnotobiotic B6.129P2-IL-10(tm1Cgn) (IL-10(-/-) ) mice.	Whary MT, Taylor NS, Feng Y, Ge Z, Muthupalani S, Versalovic J, Fox JG	Immunology	10.1111/j.1365-2567.2011.03423.x	2011	*

References

#20215

Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )

#20218

Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )

#32776 Collection of Institut Pasteur ; Curators of the CIP; CIP 104102
#56478 Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 44777

#66792

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#66794

Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg: BRENDA, the ELIXIR core data resource in 2021: new developments and updates. Nucleic Acids Res. 49: D498 - D508 2020 ( DOI 10.1093/nar/gkaa1025 , PubMed 33211880 )

#69480

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

* These data were automatically processed and therefore are not curated

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