Pseudonocardia autotrophica (DSM 535, ATCC 19727, CBS 466.68)

Name: Pseudonocardia autotrophica (DSM 535, ATCC 19727, CBS 466.68)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 13324

Type strain

Strain Designation 394, Kodai

Culture col. no. DSM 535 ATCC 19727 CBS 466.68 DSM 40011 DSM 43210 23 more

NCBI tax ID(s) 2074

Special Collections DSMZ JCM KCTC CIP

History <- IMG <- P. Hirsch, 394 <- A. Takamiya, Kodai KCC S-0348 <-- IFO 12743 <-- SAJ <-- ISP 5011 <-- A. Takamiya aa-1-1. CIP <- 2001, CCM <- R. E. Gordon <- H. G. Schlegel <- P. Hirsch <- A. Takamiya

Links

Pseudonocardia autotrophica 394 is an obligate aerobe, Gram-positive, rod-shaped bacterium that was isolated from phosphate buffer.

Gram-positive rod-shaped obligate aerobe genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 88622

ATCC 19727,DSM 535,DSM 40011,DSM 43210,IFO 12743,IMET 7646,NRRL B-11275,JCM 4348,CCM 2750,CCRC 12444,NCIMB 9810,VKM Ac-941,KCTC 9574,CBS 466.68,KCTC9564,CECT 3301,KCTC 1816,KCTC 9300,CIP 107114,NBRC 12743,BCRC 12444,NCIB 9810,CGMCC 4.1297,AS 4.1211,CGMCC 4.1211,CECT 7671

@ref 20215

Last LPSN update 2026-02-09 11:21:06

Domain Bacteria

Phylum Actinomycetota

Class Actinomycetes

Order Pseudonocardiales

Family Pseudonocardiaceae

Genus Pseudonocardia

Species Pseudonocardia autotrophica

Full scientific name Pseudonocardia autotrophica (Takamiya and Tubaki 1956) Warwick et al. 1994

Synonyms (4)

Nocardia autotrophica
"Proactinomyces autotrophicus"
"Streptomyces autotrophicus"
Amycolata autotrophica

BacDive ID	Other strains from **Pseudonocardia autotrophica** (29)	Type strain
13325	P. autotrophica DSM 43082, IMRU 418, NRRL B-1365
13326	P. autotrophica 543, DSM 43083, IMRU 543
13327	P. autotrophica DSM 43084, IMRU 703
13328	P. autotrophica 9964 A, DSM 43085, IMRU 704
13329	P. autotrophica DSM 43086, IMRU 1105
13330	P. autotrophica A 588, DSM 43087, IMRU 1124
13331	P. autotrophica 3300, DSM 43088, IMRU 1299, NRRL B-16063
13332	P. autotrophica F354, DSM 43090, IMRU 1309
13333	P. autotrophica 8 (unidentified isolate), DSM 43091, IMRU ...
13334	P. autotrophica U4, DSM 43093, IMRU 1334
13335	P. autotrophica 7-34, DSM 43094, IMRU 1335
13336	P. autotrophica Boots Pure Drug Co., strain 116, 116, Boots ...
13337	P. autotrophica DSM 43096, DSM 43190, IMRU 1338, NCIB 9574
13338	P. autotrophica B-831a, DSM 43097, IMRU 1357
13339	P. autotrophica DSM 43098, DSM 652, IMRU 1398
13340	P. autotrophica DSM 43099, IMRU 1446, NRRL B-16065, RM 66A
13341	P. autotrophica 147, DSM 43100, IMRU 1523
13342	P. autotrophica G-216, DSM 43101, IMRU 1528
13343	P. autotrophica W 1961, DSM 43102, IMRU 1576
13344	P. autotrophica W 1962, DSM 43103, DSM 43211, DSM 651, IMRU ...
13345	P. autotrophica W 1963, DSM 43104, IMRU 1578
13346	P. autotrophica W 1995, DSM 43105, IMRU 1579
13347	P. autotrophica N 37, DSM 43106, IMRU 1597
13348	P. autotrophica CM 1512, DSM 43107, IMRU 1598
13349	P. autotrophica DSM 43108, IMRU 3520
13350	P. autotrophica DSM 43128, LBG A 3006, ETH 24301
13351	P. autotrophica DSM 43558, CBS 605.67, SN 6600
105408	P. autotrophica ST033331(HKI),
164922	P. autotrophica JCM 4010, KCTC 9567, VKM Ac-1067

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Confidence
116652	positive	rod-shaped
125439	positive		99.1
125438	positive		90.351

Colony morphology

Multimedia

@ref:	130
multimedia content:	DSM_535.jpg
multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_535.jpg
caption:	Medium 65 28°C
intellectual property rights:	© Leibniz-Institut DSMZ
manual_annotation:	1

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
33085	MEDIUM 57 - for Streptomyces, Nocardioides, Lentzea albidocapillata and Streptoverticillium reticulum		Distilled water make up to (1000.000 ml);Agar (15.000 g);Glucose (4.000g);Yeast extract (4.000 g);Malt extract (10.000 g);Calcium carbonate (2.000 g)
130	TRYPTICASE SOY BROTH AGAR (DSMZ Medium 535)	Medium recipe at MediaDive	Name: TRYPTICASE SOY BROTH AGAR (DSMZ Medium 535) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Distilled water
130	GYM STREPTOMYCES MEDIUM (DSMZ Medium 65)	Medium recipe at MediaDive	Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 18.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water
116652	CIP Medium 57	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)
130	positive	growth	28
33085	positive	growth	30
67770	positive	growth	28
116652	positive	growth	10-37
116652	negative	growth	41

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
116652	obligate aerobe
125438	aerobe	92.076
125439	obligate aerobe	99.5

Halophily

@ref	Salt	Growth	Tested relation	Concentration
116652	NaCl	positive	growth	4 %
116652	NaCl		growth	0 %
116652	NaCl		growth	2 %
116652	NaCl		growth	6 %
116652	NaCl		growth	8 %
116652	NaCl		growth	10 %

Observation

67770

Observationquinones: MK-8(H₄), MK-8(H₂), MK-8(H₄)

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68371	27613 ChEBI	amygdalin	-	builds acid from	from API 50CH acid
68371	18305 ChEBI	arbutin	-	builds acid from	from API 50CH acid
68371	17057 ChEBI	cellobiose	-	builds acid from	from API 50CH acid
68371	17108 ChEBI	D-arabinose	-	builds acid from	from API 50CH acid
68371	18333 ChEBI	D-arabitol	-	builds acid from	from API 50CH acid
68371	15824 ChEBI	D-fructose	-	builds acid from	from API 50CH acid
68371	28847 ChEBI	D-fucose	-	builds acid from	from API 50CH acid
68371	12936 ChEBI	D-galactose	-	builds acid from	from API 50CH acid
68371	17634 ChEBI	D-glucose	-	builds acid from	from API 50CH acid
68371	62318 ChEBI	D-lyxose	-	builds acid from	from API 50CH acid
68371	16899 ChEBI	D-mannitol	-	builds acid from	from API 50CH acid
68371	16024 ChEBI	D-mannose	-	builds acid from	from API 50CH acid
68371	16988 ChEBI	D-ribose	-	builds acid from	from API 50CH acid
68371	17924 ChEBI	D-sorbitol	-	builds acid from	from API 50CH acid
68371	65327 ChEBI	D-xylose	-	builds acid from	from API 50CH acid
68371	17113 ChEBI	erythritol	-	builds acid from	from API 50CH acid
116652	4853 ChEBI	esculin	-	hydrolysis
68371	4853 ChEBI	esculin	-	builds acid from	from API 50CH acid
68371	16813 ChEBI	galactitol	-	builds acid from	from API 50CH acid
68371	28066 ChEBI	gentiobiose	-	builds acid from	from API 50CH acid
68371	24265 ChEBI	gluconate	-	builds acid from	from API 50CH acid
68371	17754 ChEBI	glycerol	-	builds acid from	from API 50CH acid
68371	28087 ChEBI	glycogen	-	builds acid from	from API 50CH acid
116652	606565 ChEBI	hippurate	-	hydrolysis
68371	15443 ChEBI	inulin	-	builds acid from	from API 50CH acid
68371	30849 ChEBI	L-arabinose	-	builds acid from	from API 50CH acid
68371	18403 ChEBI	L-arabitol	-	builds acid from	from API 50CH acid
68371	18287 ChEBI	L-fucose	-	builds acid from	from API 50CH acid
68371	62345 ChEBI	L-rhamnose	-	builds acid from	from API 50CH acid
68371	17266 ChEBI	L-sorbose	-	builds acid from	from API 50CH acid
68371	65328 ChEBI	L-xylose	-	builds acid from	from API 50CH acid
68371	17716 ChEBI	lactose	-	builds acid from	from API 50CH acid
68371	17306 ChEBI	maltose	-	builds acid from	from API 50CH acid
68371	6731 ChEBI	melezitose	-	builds acid from	from API 50CH acid
68371	28053 ChEBI	melibiose	-	builds acid from	from API 50CH acid
68371	320061 ChEBI	methyl alpha-D-glucopyranoside	-	builds acid from	from API 50CH acid
68371	43943 ChEBI	methyl alpha-D-mannoside	-	builds acid from	from API 50CH acid
68371	74863 ChEBI	methyl beta-D-xylopyranoside	-	builds acid from	from API 50CH acid
68371	17268 ChEBI	myo-inositol	-	builds acid from	from API 50CH acid
68371	59640 ChEBI	N-acetylglucosamine	-	builds acid from	from API 50CH acid
116652	17632 ChEBI	nitrate	+	reduction
116652	17632 ChEBI	nitrate	-	respiration
116652	16301 ChEBI	nitrite	-	reduction
68371		Potassium 2-ketogluconate	-	builds acid from	from API 50CH acid
68371	16634 ChEBI	raffinose	-	builds acid from	from API 50CH acid
68371	15963 ChEBI	ribitol	-	builds acid from	from API 50CH acid
68371	17814 ChEBI	salicin	-	builds acid from	from API 50CH acid
68371	28017 ChEBI	starch	-	builds acid from	from API 50CH acid
68371	17992 ChEBI	sucrose	-	builds acid from	from API 50CH acid
68371	27082 ChEBI	trehalose	-	builds acid from	from API 50CH acid
68371	32528 ChEBI	turanose	-	builds acid from	from API 50CH acid
68371	17151 ChEBI	xylitol	-	builds acid from	from API 50CH acid

Antibiotic resistance

@ref	Metabolite	Is sensitive	Is resistant
116652	0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate)

Metabolite production

@ref	Chebi-ID	Metabolite	Production
116652	35581 ChEBI	indole

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test	Methylred-test
116652	15688 ChEBI	acetoin	-
116652	17234 ChEBI	glucose		-

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	-	3.1.3.2	from API zym
116652	alcohol dehydrogenase	-	1.1.1.1
68382	alkaline phosphatase	+	3.1.3.1	from API zym
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68382	alpha-glucosidase	+	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
116652	amylase	-
68382	beta-galactosidase	-	3.2.1.23	from API zym
116652	beta-galactosidase	+	3.2.1.23
68382	beta-glucosidase	-	3.2.1.21	from API zym
68382	beta-glucuronidase	-	3.2.1.31	from API zym
116652	caseinase	-	3.4.21.50
116652	catalase	+	1.11.1.6
68382	cystine arylamidase	-	3.4.11.3	from API zym
116652	DNase	-
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
116652	gamma-glutamyltransferase	-	2.3.2.2
116652	gelatinase	-
116652	lecithinase	-
68382	leucine arylamidase	+	3.4.11.1	from API zym
116652	lipase	-
68382	lipase (C 14)	-		from API zym
116652	lysine decarboxylase	-	4.1.1.18
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68382	naphthol-AS-BI-phosphohydrolase	-		from API zym
116652	ornithine decarboxylase	-	4.1.1.17
116652	oxidase	-
116652	phenylalanine ammonia-lyase	-	4.3.1.24
68382	trypsin	-	3.4.21.4	from API zym
116652	tryptophan deaminase	-
116652	tween esterase	-
116652	urease	+	3.5.1.5
68382	valine arylamidase	+		from API zym

Pathway annotation

Computationally determined by

@ref	pathway	enzyme coverage	annotated reactions
66794	valine metabolism	100	9 of 9
66794	adipate degradation	100	2 of 2
66794	gallate degradation	100	5 of 5
66794	methylglyoxal degradation	100	5 of 5
66794	CMP-KDO biosynthesis	100	4 of 4
66794	cardiolipin biosynthesis	100	7 of 7
66794	Entner Doudoroff pathway	100	10 of 10
66794	cis-vaccenate biosynthesis	100	2 of 2
66794	ethylmalonyl-CoA pathway	100	5 of 5
66794	ethanol fermentation	100	2 of 2
66794	octane oxidation	100	3 of 3
66794	enterobactin biosynthesis	100	3 of 3
66794	phenylmercury acetate degradation	100	2 of 2
66794	resorcinol degradation	100	2 of 2
66794	IAA biosynthesis	100	3 of 3
66794	ppGpp biosynthesis	100	4 of 4
66794	biotin biosynthesis	100	4 of 4
66794	L-lactaldehyde degradation	100	3 of 3
66794	palmitate biosynthesis	100	22 of 22
66794	photosynthesis	100	14 of 14
66794	phenylacetate degradation (aerobic)	100	5 of 5
66794	coenzyme A metabolism	100	4 of 4
66794	CDP-diacylglycerol biosynthesis	100	2 of 2
66794	reductive acetyl coenzyme A pathway	100	7 of 7
66794	suberin monomers biosynthesis	100	2 of 2
66794	folate polyglutamylation	100	1 of 1
66794	glycine betaine biosynthesis	100	5 of 5
66794	glycolate and glyoxylate degradation	100	6 of 6
66794	cyanate degradation	100	3 of 3
66794	taurine degradation	100	1 of 1
66794	UDP-GlcNAc biosynthesis	100	3 of 3
66794	anapleurotic synthesis of oxalacetate	100	1 of 1
66794	formaldehyde oxidation	100	3 of 3
66794	vitamin K metabolism	100	5 of 5
66794	citric acid cycle	92.86	13 of 14
66794	phenylalanine metabolism	92.31	12 of 13
66794	leucine metabolism	92.31	12 of 13
66794	propionate fermentation	90	9 of 10
66794	myo-inositol biosynthesis	90	9 of 10
66794	phenol degradation	90	18 of 20
66794	threonine metabolism	90	9 of 10
66794	serine metabolism	88.89	8 of 9
66794	CO2 fixation in Crenarchaeota	88.89	8 of 9
66794	4-hydroxymandelate degradation	88.89	8 of 9
66794	chorismate metabolism	88.89	8 of 9
66794	aspartate and asparagine metabolism	88.89	8 of 9
66794	molybdenum cofactor biosynthesis	88.89	8 of 9
66794	C4 and CAM-carbon fixation	87.5	7 of 8
66794	gluconeogenesis	87.5	7 of 8
66794	ketogluconate metabolism	87.5	7 of 8
66794	flavin biosynthesis	86.67	13 of 15
66794	tetrahydrofolate metabolism	85.71	12 of 14
66794	propanol degradation	85.71	6 of 7
66794	purine metabolism	84.04	79 of 94
66794	NAD metabolism	83.33	15 of 18
66794	degradation of aromatic, nitrogen containing compounds	83.33	10 of 12
66794	glutamate and glutamine metabolism	82.14	23 of 28
66794	pentose phosphate pathway	81.82	9 of 11
66794	methionine metabolism	80.77	21 of 26
66794	3-phenylpropionate degradation	80	12 of 15
66794	factor 420 biosynthesis	80	4 of 5
66794	3-chlorocatechol degradation	80	4 of 5
66794	starch degradation	80	8 of 10
66794	cellulose degradation	80	4 of 5
66794	peptidoglycan biosynthesis	80	12 of 15
66794	glycogen metabolism	80	4 of 5
66794	hydrogen production	80	4 of 5
66794	vitamin B12 metabolism	79.41	27 of 34
66794	tryptophan metabolism	78.95	30 of 38
66794	heme metabolism	78.57	11 of 14
66794	glutathione metabolism	78.57	11 of 14
66794	pyrimidine metabolism	77.78	35 of 45
66794	vitamin B1 metabolism	76.92	10 of 13
66794	urea cycle	76.92	10 of 13
66794	glycolysis	76.47	13 of 17
66794	non-pathway related	76.32	29 of 38
66794	butanoate fermentation	75	3 of 4
66794	glycogen biosynthesis	75	3 of 4
66794	isoleucine metabolism	75	6 of 8
66794	lactate fermentation	75	3 of 4
66794	toluene degradation	75	3 of 4
66794	acetate fermentation	75	3 of 4
66794	cyclohexanol degradation	75	3 of 4
66794	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	75	6 of 8
66794	dTDPLrhamnose biosynthesis	75	6 of 8
66794	sulfopterin metabolism	75	3 of 4
66794	lipid metabolism	74.19	23 of 31
66794	oxidative phosphorylation	73.63	67 of 91
66794	proline metabolism	72.73	8 of 11
66794	cysteine metabolism	72.22	13 of 18
66794	degradation of sugar acids	72	18 of 25
66794	aclacinomycin biosynthesis	71.43	5 of 7
66794	ubiquinone biosynthesis	71.43	5 of 7
66794	degradation of pentoses	71.43	20 of 28
66794	tyrosine metabolism	71.43	10 of 14
66794	4-hydroxyphenylacetate degradation	70	7 of 10
66794	coenzyme M biosynthesis	70	7 of 10
66794	histidine metabolism	68.97	20 of 29
66794	alanine metabolism	68.97	20 of 29
66794	degradation of sugar alcohols	68.75	11 of 16
66794	androgen and estrogen metabolism	68.75	11 of 16
66794	methane metabolism	66.67	2 of 3
66794	d-mannose degradation	66.67	6 of 9
66794	acetoin degradation	66.67	2 of 3
66794	sulfoquinovose degradation	66.67	2 of 3
66794	isoprenoid biosynthesis	65.38	17 of 26
66794	metabolism of disaccharids	63.64	7 of 11
66794	d-xylose degradation	63.64	7 of 11
66794	carotenoid biosynthesis	63.64	14 of 22
66794	sulfate reduction	61.54	8 of 13
66794	metabolism of amino sugars and derivatives	60	3 of 5
66794	lipoate biosynthesis	60	3 of 5
66794	lysine metabolism	59.52	25 of 42
66794	arginine metabolism	58.33	14 of 24
66794	degradation of hexoses	55.56	10 of 18
66794	daunorubicin biosynthesis	55.56	5 of 9
66794	glycine metabolism	50	5 of 10
66794	sphingosine metabolism	50	3 of 6
66794	dolichol and dolichyl phosphate biosynthesis	50	1 of 2
66794	selenocysteine biosynthesis	50	3 of 6
66794	ribulose monophosphate pathway	50	1 of 2
66794	aminopropanol phosphate biosynthesis	50	1 of 2
66794	quinate degradation	50	1 of 2
66794	vitamin E metabolism	50	2 of 4
66794	carnitine metabolism	50	4 of 8
66794	mannosylglycerate biosynthesis	50	1 of 2
66794	pantothenate biosynthesis	50	3 of 6
66794	bile acid biosynthesis, neutral pathway	47.06	8 of 17
66794	phosphatidylethanolamine bioynthesis	46.15	6 of 13
66794	vitamin B6 metabolism	45.45	5 of 11
66794	cholesterol biosynthesis	45.45	5 of 11
66794	nitrate assimilation	44.44	4 of 9
66794	lipid A biosynthesis	44.44	4 of 9
66794	allantoin degradation	44.44	4 of 9
66794	benzoyl-CoA degradation	42.86	3 of 7
66794	creatinine degradation	40	2 of 5
66794	arachidonate biosynthesis	40	2 of 5
66794	ascorbate metabolism	36.36	8 of 22
66794	polyamine pathway	34.78	8 of 23
66794	chlorophyll metabolism	33.33	6 of 18
66794	(5R)-carbapenem carboxylate biosynthesis	33.33	1 of 3
66794	acetyl CoA biosynthesis	33.33	1 of 3
66794	arachidonic acid metabolism	27.78	5 of 18
66794	dolichyl-diphosphooligosaccharide biosynthesis	27.27	3 of 11
66794	catecholamine biosynthesis	25	1 of 4
66794	methanogenesis from CO2	25	3 of 12

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
116652	-	+	+	+	-	+	+	-	-	-	-	-	-	-	-	+	-	-	-	-

API 50CHac

@ref	ControlQ	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
116652	not determinedn.d.	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+/-	-	-	-	-	-	-	+/-

API biotype100

@ref	ControlQ	D-glucose as carbon sourceGLU	D-fructose as carbon sourceFRU	D-galactose as carbon sourceGAL	D-trehalose as carbon sourceTRE	D-mannose as carbon sourceMNE	L-sorbose as carbon sourceSBE	D-melibiose as carbon sourceMEL	sucrose as carbon sourceSAC	D-raffinose as carbon sourceRAF	maltotriose as carbon sourceMTE	maltose as carbon sourceMAL	lactose as carbon sourceLAC	lactulose as carbon sourceLTE	1-O-methyl-beta-galactopyranoside as carbon sourceMbGa	1-O-methyl-alpha-galactopyranoside as carbon sourceMaGa	D-cellobiose as carbon sourceCEL	gentiobiose as carbon sourceGEN	1-O-methyl-beta-D-glucopyranoside as carbon sourceMbGu	esculin as carbon sourceESC	D-ribose as carbon sourceRIB	L-arabinose as carbon sourceARA	D-xylose as carbon sourceXYL	palatinose as carbon sourcePLE	L-rhamnose as carbon sourceRHA	L-fucose as carbon sourceFUC	D-melezitose as carbon sourceMLZ	D-arabitol as carbon sourceDARL	L-arabitol as carbon sourceLARL	xylitol as carbon sourceXLT	dulcitol as carbon sourceDUL	D-tagatose as carbon sourceTAG	glycerol as carbon sourceGLY	myo-inositol as carbon sourceINO	D-mannitol as carbon sourceMAN	maltitol as carbon sourceMTL	D-turanose as carbon sourceTUR	D-sorbitol as carbon sourceSOR	adonitol as carbon sourceADO	hydroxyquinoline-beta-glucuronide as carbon sourceHBG	D-lyxose as carbon sourceLYX	i-erythritol as carbon sourceERY	1-O-methyl-alpha-D-glucoside as carbon sourceMDG	3-O-methyl-D-glucose as carbon source3MDG	D-saccharate as carbon sourceSAT	mucate as carbon sourceMUC	L-tartrate as carbon sourceLTAT	D-tartrate as carbon sourceDTAT	meso-tartrate as carbon sourceMTAT	D-malate as carbon sourceDMLT	L-malate as carbon sourceLMLT	cis-aconitate as carbon sourceCATE	trans-aconitate as carbon sourceTATE	tricarballylate as carbon sourceTTE	citrate as carbon sourceCIT	D-glucuronate as carbon sourceGRT	D-galacturonate as carbon sourceGAT	2-ketogluconate as carbon source2KG	5-ketogluconate as carbon source5KG	tryptophan as carbon sourceTRY	N-acetyl-D-glucosamine as carbon sourceNAG	D-gluconate as carbon sourceGNT	phenylacetate as carbon sourcePAC	protocatechuate as carbon sourcePAT	4-hydroxybenzoate as carbon sourcepOBE	quinate as carbon sourceQAT	gentisate as carbon sourceGTE	3-hydroxybenzoate as carbon sourcemOBE	benzoate as carbon sourceBAT	3-phenylpropionate as carbon sourcePPAT	m-coumarate as carbon sourceCMT	trigonelline as carbon sourceTGE	betaine as carbon sourceBET	putrescine as carbon sourcePCE	4-aminobutyrate as carbon sourceABT	histamine as carbon sourceHIN	DL-lactate as carbon sourceLAT	caprate as carbon sourceCAP	caprylate as carbon sourceCYT	L-histidine as carbon sourceHIS	succinate as carbon sourceSUC	fumarate as carbon sourceFUM	glutarate as carbon sourceGRE	DL-glycerate as carbon sourceGYT	5-aminovalerate as carbon sourceAVT	ethanolamine as carbon sourceETN	tryptamine as carbon sourceTTN	D-glucosamine as carbon sourceGLN	itaconate as carbon sourceITA	3-hydroxybutyrate as carbon source3OBU	L-aspartate as carbon sourceAPT	L-glutamate as carbon sourceGTT	L-proline as carbon sourcePRO	D-alanine as carbon sourceDALA	L-alanine as carbon sourceLALA	L-serine as carbon sourceSER	malonate as carbon sourceMNT	propionate as carbon sourcePROP	L-tyrosine as carbon sourceTYR	2-ketoglutarate as carbon source2KT
116652	not determinedn.d.	+	+	+	+	+	-	-	+	-	-	+	-	-	-	-	+	-	-	-	+	+	+	-	-	-	+	+	-	-	-	-	+	+	+	+	+	+	+	-	-	+	-	-	-	-	-	-	-	+	+	-	-	-	-	-	-	+	+	-	+	-	-	+	-	-	+	+	-	-	-	+	+	-	-	-	+	-	-	-	+	+	-	-	-	-	-	+	-	+	-	+	+	-	-	-	+	+	+	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2
#Engineered	#Laboratory

Isolation

@ref	Sample type
130	phosphate buffer
116652	Contaminant in a phosphate buffer solution

Taxonmaps

69479

Global distribution of 16S sequence EU928972 (>99% sequence identity) for Pseudonocardia from Microbeatlas

Aquatic Samples	61
Soil Samples	68
Animal Samples	190
Plant Samples	20
Total Samples	339

Interaction and safety

Risk assessment

@ref	Pathogenicity human	Biosafety level	Biosafety level comment
130	yes, in single cases	1	Risk group (German classification) According to TRBA 466
116652		2	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM394538v1 assembly for Pseudonocardia autotrophica NBRC 12743	complete	GCA_003945385	2074.11	2856823606	2074	93.08
67770	ASM436196v1 assembly for Pseudonocardia autotrophica DSM 535	contig	GCA_004361965	2074.12	2756170255	2074	72.69
67770	ASM211921v1 assembly for Pseudonocardia autotrophica DSM 535	contig	GCA_002119215	2074.6	2856837300	2074	51.05

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Pseudonocardia autotrophica 16S ribosomal RNA gene, partial sequence	EU928972	1380	2074
20218	Amycolata autotrophica (Nocardia a.) partial 16S rRNA	X54288	1332	2074
20218	Pseudonocardia autotrophica 16S rRNA gene, strain IMSNU 20050T	AJ252824	1512	2074

GC content

@ref	GC-content (mol%)	Method
67770	73	genome sequence analysis
67770	72	thermal denaturation, midpoint method (Tm)
67770	70	thermal denaturation, midpoint method (Tm)

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Pseudonocardia autotrophica NBRC 12743
NCBI: GCA_003945385

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	yes	78.60	no
125439	motility	BacteriaNetⓘ	no	78.90	no
125439	gram_stain	BacteriaNetⓘ	positive	99.10	no
125439	oxygen_tolerance	BacteriaNetⓘ	obligate aerobe	99.50	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Pseudonocardia autotrophica NBRC 12743
NCBI: GCA_003945385.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	90.35	no
125438	anaerobic	anaerobicⓘ	no	96.05	no
125438	aerobic	aerobicⓘ	yes	92.08	yes
125438	spore-forming	spore-formingⓘ	yes	68.05	no
125438	thermophilic	thermophileⓘ	no	96.35	no
125438	flagellated	motile2+ⓘ	no	88.00	no

Literature

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Enzymology	Thermophilic and alkaliphilic Actinobacteria: biology and potential applications.	Shivlata L, Satyanarayana T.	Front Microbiol	10.3389/fmicb.2015.01014	2015
	Biotransformation of selected secondary metabolites by Alternaria species and the pharmaceutical, food and agricultural application of biotransformation products.	Tembeni B, Idowu OE, Benrkia R, Boutahiri S, Olatunji OJ.	Nat Prod Bioprospect	10.1007/s13659-024-00469-5	2024
	Bioconversion of vitamin D₃ to bioactive calcifediol and calcitriol as high-value compounds.	Wang Z, Zeng Y, Jia H, Yang N, Liu M, Jiang M, Zheng Y.	Biotechnol Biofuels Bioprod	10.1186/s13068-022-02209-8	2022
	Vitamins as regulators of calcium-containing kidney stones - new perspectives on the role of the gut microbiome.	Chmiel JA, Stuivenberg GA, Al KF, Akouris PP, Razvi H, Burton JP, Bjazevic J.	Nat Rev Urol	10.1038/s41585-023-00768-5	2023
Enzymology	Selective Oxidation of Vitamin D₃ Enhanced by Long-Range Effects of a Substrate Channel Mutation in Cytochrome P450_BM3 (CYP102A1).	Chen W, Lynch JNC, Bustamante C, Zhang Y, Wong LL.	Chemistry	10.1002/chem.202401487	2024
	Streptomyces BAC Cloning of a Large-Sized Biosynthetic Gene Cluster of NPP B1, a Potential SARS-CoV-2 RdRp Inhibitor.	Park JH, Park HS, Nah HJ, Kang SH, Choi SS, Kim ES.	J Microbiol Biotechnol	10.4014/jmb.2205.05036	2022
	Update of the list of QPS-recommended microbiological agents intentionally added to food or feed as notified to EFSA 16: suitability of taxonomic units notified to EFSA until March 2022.	EFSA Panel on Biological Hazards (BIOHAZ), Koutsoumanis K, Allende A, Alvarez-Ordonez A, Bolton D, Bover-Cid S, Chemaly M, Davies R, De Cesare A, Hilbert F, Lindqvist R, Nauta M, Peixe L, Ru G, Simmons M, Skandamis P, Suffredini E, Cocconcelli PS, Fernandez Escamez PS, Maradona MP, Querol A, Sijtsma L, Suarez JE, Sundh I, Vlak J, Barizzone F, Hempen M, Correia S, Herman L.	EFSA J	10.2903/j.efsa.2022.7408	2022
Metabolism	Improved recovery and biological activities of an engineered polyene NPP analogue in Pseudonocardia autotrophica.	Won HJ, Kim HJ, Jang JY, Kang SH, Choi SS, Kim ES.	J Ind Microbiol Biotechnol	10.1007/s10295-017-1954-8	2017
Metabolism	Pseudonocardia strain improvement for stimulation of the di-sugar heptaene Nystatin-like Pseudonocardia polyene B1 biosynthesis.	Han CY, Jang JY, Kim HJ, Choi S, Kim ES.	J Ind Microbiol Biotechnol	10.1007/s10295-019-02149-7	2019
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	Stimulated Biosynthesis of an C10-Deoxy Heptaene NPP B2 via Regulatory Genes Overexpression in Pseudonocardia autotrophica.	Park HS, Kim HJ, Han CY, Nah HJ, Choi SS, Kim ES.	Front Microbiol	10.3389/fmicb.2020.00019	2020
Metabolism	Carboxyl-terminal domain characterization of polyene-specific P450 hydroxylase in Pseudonocardia autotrophica.	Kim MK, Won HJ, Kim HJ, Choi SS, Lee HS, Kim P, Kim ES.	J Ind Microbiol Biotechnol	10.1007/s10295-016-1813-z	2016
	Structure-Function Analysis of the Biotechnologically Important Cytochrome P450 107 (CYP107) Enzyme Family.	Padayachee T, Lamb DC, Nelson DR, Syed K.	Biomolecules	10.3390/biom13121733	2023
	Characterization of vitamin D3 biotransformation by the cell lysate of Actinomyces hyovaginalis CCASU-A11-2.	Abbas AM, Elkhatib WF, Aboulwafa MM, Hassouna NA, Aboshanab KM.	AMB Express	10.1186/s13568-024-01694-4	2024
	Engineered biosynthesis and characterization of disaccharide-pimaricin.	Zuo X, Qiao L, Dong Y, Jin X, Ren Z, Cui H.	Microb Cell Fact	10.1186/s12934-025-02742-9	2025
Enzymology	Biochemical and structural characterization of CYP109A2, a vitamin D₃ 25-hydroxylase from Bacillus megaterium.	Abdulmughni A, Jozwik IK, Brill E, Hannemann F, Thunnissen AWH, Bernhardt R.	FEBS J	10.1111/febs.14276	2017
Metabolism	Redesign of antifungal polyene glycosylation: engineered biosynthesis of disaccharide-modified NPP.	Kim HJ, Kang SH, Choi SS, Kim ES.	Appl Microbiol Biotechnol	10.1007/s00253-017-8303-8	2017
Pathogenicity	Engineered biosynthesis and characterisation of disaccharide-modified 8-deoxyamphoteronolides.	Walmsley S, De Poire E, Rawlings B, Caffrey P.	Appl Microbiol Biotechnol	10.1007/s00253-016-7986-6	2017
Metabolism	In vitro reconstitution of the cyclosporine specific P450 hydroxylases using heterologous redox partner proteins.	Sun Y, Ma L, Han D, Du L, Qi F, Zhang W, Sun J, Huang S, Kim ES, Li S.	J Ind Microbiol Biotechnol	10.1007/s10295-016-1875-y	2017
Metabolism	Effect of antibiotic down-regulatory gene wblA ortholog on antifungal polyene production in rare actinomycetes Pseudonocardia autotrophica.	Kim HJ, Kim MK, Jin YY, Kim ES.	J Microbiol Biotechnol	10.4014/jmb.1406.06018	2014
Genetics	Exploring extreme environments in Türkiye for novel P450s through metagenomic analysis.	Mumcu H, Zaugg J, Keles I, Kayrav A, Balci N, Nelson DR, Hugenholtz P, Gillam EMJ, Gul Karaguler N.	PLoS One	10.1371/journal.pone.0330523	2025
Metabolism	Polyene macrolide biosynthesis in streptomycetes and related bacteria: recent advances from genome sequencing and experimental studies.	Caffrey P, De Poire E, Sheehan J, Sweeney P.	Appl Microbiol Biotechnol	10.1007/s00253-016-7474-z	2016
Metabolism	Domain Characterization of Cyclosporin Regio-Specific Hydroxylases in Rare Actinomycetes.	Woo MW, Lee BR, Nah HJ, Choi SS, Li S, Kim ES.	J Microbiol Biotechnol	10.4014/jmb.1505.05034	2015
	Nystatin-like Pseudonocardia polyene B1, a novel disaccharide-containing antifungal heptaene antibiotic.	Kim HJ, Han CY, Park JS, Oh SH, Kang SH, Choi SS, Kim JM, Kwak JH, Kim ES.	Sci Rep	10.1038/s41598-018-31801-y	2018
Metabolism	Structural analysis and biosynthetic engineering of a solubility-improved and less-hemolytic nystatin-like polyene in Pseudonocardia autotrophica.	Lee MJ, Kong D, Han K, Sherman DH, Bai L, Deng Z, Lin S, Kim ES.	Appl Microbiol Biotechnol	10.1007/s00253-012-3955-x	2012
Metabolism	A single mutation at the ferredoxin binding site of P450 Vdh enables efficient biocatalytic production of 25-hydroxyvitamin D(3).	Yasutake Y, Nishioka T, Imoto N, Tamura T.	Chembiochem	10.1002/cbic.201300386	2013
	Crystal Structure and Biochemical Analysis of a Cytochrome P450 Steroid Hydroxylase (BaCYP106A6) from Bacillus Species.	Kim KH, Do H, Lee CW, Subedi P, Choi M, Nam Y, Lee JH, Oh TJ.	J Microbiol Biotechnol	10.4014/jmb.2211.11031	2023
	Enrichment of halotolerant hydrogen-oxidizing bacteria and production of high-value-added chemical hydroxyectoine using a hybrid biological-inorganic system.	Feng X, Kazama D, He S, Nakayama H, Hayashi T, Tokunaga T, Sato K, Kobayashi H.	Front Microbiol	10.3389/fmicb.2023.1254451	2023
Metabolism	Analysis and functional expression of NPP pathway-specific regulatory genes in Pseudonocardia autotrophica.	Jeon HG, Seo J, Lee MJ, Han K, Kim ES.	J Ind Microbiol Biotechnol	10.1007/s10295-011-0939-2	2011
Metabolism	Molecular characterization, modeling and docking of CYP107CB2 from Bacillus lehensis G1, an alkaliphile.	Ang SS, Salleh AB, Chor AL, Normi YM, Tejo BA, Rahman MB.	Comput Biol Chem	10.1016/j.compbiolchem.2015.02.015	2015
	Bioconversion of vitamin D₃ into calcitriol by Actinomyces hyovaginalis isolate CCASU- A11-2.	Abbas AM, Elkhatib WF, Aboulwafa MM, Hassouna NA, Aboshanab KM.	AMB Express	10.1186/s13568-023-01574-3	2023
Pathogenicity	Post-PKS tailoring steps of a disaccharide-containing polyene NPP in Pseudonocardia autotrophica.	Kim HJ, Kim MK, Lee MJ, Won HJ, Choi SS, Kim ES.	PLoS One	10.1371/journal.pone.0123270	2015
Metabolism	Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.	Kim BG, Lee MJ, Seo J, Hwang YB, Lee MY, Han K, Sherman DH, Kim ES.	J Ind Microbiol Biotechnol	10.1007/s10295-009-0629-5	2009
Metabolism	Bioconversion of vitamin D to its active form by bacterial or mammalian cytochrome P450.	Sakaki T, Sugimoto H, Hayashi K, Yasuda K, Munetsuna E, Kamakura M, Ikushiro S, Shiro Y.	Biochim Biophys Acta	10.1016/j.bbapap.2010.07.014	2011
Enzymology	Enhancement of recombinant enzyme activity in cpxA-deficient mutant of Escherichia coli.	Zhou Y, Minami T, Honda K, Omasa T, Ohtake H.	J Biosci Bioeng	10.1016/j.jbiosc.2010.04.013	2010
Pathogenicity	Isolation and identification of 2alpha,25-dihydroxyvitamin D3, a new metabolite from Pseudonocardia autotrophica 100U-19 cells incubated with Vitamin D3.	Takeda K, Kominato K, Sugita A, Iwasaki Y, Shimazaki M, Shimizu M.	Steroids	10.1016/j.steroids.2006.05.004	2006
Metabolism	Isolation and partial characterization of a cryptic polyene gene cluster in Pseudonocardia autotrophica.	Lee MY, Myeong JS, Park HJ, Han K, Kim ES.	J Ind Microbiol Biotechnol	10.1007/s10295-005-0018-7	2006
Phylogeny	Association of serum 25-hydroxyvitamin D (25(OH)D) levels with the gut microbiota and metabolites in postmenopausal women in China.	Gong J, He L, Zou Q, Zhao Y, Zhang B, Xia R, Chen B, Cao M, Gong W, Lin L, Lin X, Wang G, Guo M, He J, Xiao C, Chen J.	Microb Cell Fact	10.1186/s12934-022-01858-6	2022
Enzymology	Crystallization and preliminary X-ray diffraction studies of vitamin D3 hydroxylase, a novel cytochrome P450 isolated from Pseudonocardia autotrophica.	Yasutake Y, Fujii Y, Cheon WK, Arisawa A, Tamura T.	Acta Crystallogr Sect F Struct Biol Cryst Commun	10.1107/s1744309109007829	2009
Metabolism	Investigation of Vitamin D₂ and Vitamin D₃ Hydroxylation by Kutzneria albida.	Schmitz LM, Kinner A, Althoff K, Rosenthal K, Lutz S.	Chembiochem	10.1002/cbic.202100027	2021
	Structure-guided manipulation of the regioselectivity of the cyclosporine A hydroxylase CYP-sb21 from Sebekia benihana.	Li F, Ma L, Zhang X, Chen J, Qi F, Huang Y, Qu Z, Yao L, Zhang W, Kim ES, Li S.	Synth Syst Biotechnol	10.1016/j.synbio.2020.07.004	2020
Metabolism	Engineered biosynthesis of disaccharide-modified polyene macrolides.	De Poire E, Stephens N, Rawlings B, Caffrey P.	Appl Environ Microbiol	10.1128/aem.02197-13	2013
Metabolism	Comparative Analysis, Structural Insights, and Substrate/Drug Interaction of CYP128A1 in Mycobacterium tuberculosis.	Ngcobo NS, Chiliza ZE, Chen W, Yu JH, Nelson DR, Tuszynski JA, Preto J, Syed K.	Int J Mol Sci	10.3390/ijms21144816	2020
	Strain Improvement of Streptomyces xanthochromogenes RIA 1098 for Enhanced Pravastatin Production at High Compactin Concentrations.	Dzhavakhiya VV, Voinova TM, Glagoleva EV, Petukhov DV, Ovchinnikov AI, Kartashov MI, Kuznetsov BB, Skryabin KG.	Indian J Microbiol	10.1007/s12088-015-0537-5	2015
Metabolism	Characterization of the biosynthetic gene cluster of the polyene macrolide antibiotic reedsmycins from a marine-derived Streptomyces strain.	Yao T, Liu Z, Li T, Zhang H, Liu J, Li H, Che Q, Zhu T, Li D, Li W.	Microb Cell Fact	10.1186/s12934-018-0943-6	2018
Metabolism	Selvamicin, an atypical antifungal polyene from two alternative genomic contexts.	Van Arnam EB, Ruzzini AC, Sit CS, Horn H, Pinto-Tomas AA, Currie CR, Clardy J.	Proc Natl Acad Sci U S A	10.1073/pnas.1613285113	2016
	Structural insights into the mechanism of the drastic changes in enzymatic activity of the cytochrome P450 vitamin D₃ hydroxylase (CYP107BR1) caused by a mutation distant from the active site.	Yasutake Y, Kameda T, Tamura T.	Acta Crystallogr F Struct Biol Commun	10.1107/s2053230x17004782	2017
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Enzymology	Pseudonocardians A-C, new diazaanthraquinone derivatives from a deap-sea actinomycete Pseudonocardia sp. SCSIO 01299.	Li S, Tian X, Niu S, Zhang W, Chen Y, Zhang H, Yang X, Zhang W, Li W, Zhang S, Ju J, Zhang C.	Mar Drugs	10.3390/md9081428	2011
Enzymology	Structural evidence for enhancement of sequential vitamin D3 hydroxylation activities by directed evolution of cytochrome P450 vitamin D3 hydroxylase.	Yasutake Y, Fujii Y, Nishioka T, Cheon WK, Arisawa A, Tamura T.	J Biol Chem	10.1074/jbc.m110.147009	2010
Metabolism	A mixed community of actinomycetes produce multiple antibiotics for the fungus farming ant Acromyrmex octospinosus.	Barke J, Seipke RF, Gruschow S, Heavens D, Drou N, Bibb MJ, Goss RJ, Yu DW, Hutchings MI.	BMC Biol	10.1186/1741-7007-8-109	2010
Genetics	Genome Analysis of Two Pseudonocardia Phylotypes Associated with Acromyrmex Leafcutter Ants Reveals Their Biosynthetic Potential.	Holmes NA, Innocent TM, Heine D, Bassam MA, Worsley SF, Trottmann F, Patrick EH, Yu DW, Murrell JC, Schiott M, Wilkinson B, Boomsma JJ, Hutchings MI.	Front Microbiol	10.3389/fmicb.2016.02073	2016
Enzymology	A Rhodococcus qsdA-encoded enzyme defines a novel class of large-spectrum quorum-quenching lactonases.	Uroz S, Oger PM, Chapelle E, Adeline MT, Faure D, Dessaux Y.	Appl Environ Microbiol	10.1128/aem.02014-07	2008
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Metabolism	Investigation of the biosynthetic potential of endophytes in traditional Chinese anticancer herbs.	Miller KI, Qing C, Sze DM, Neilan BA.	PLoS One	10.1371/journal.pone.0035953	2012
Genetics	New vector system for random, single-step integration of multiple copies of DNA into the Rhodococcus genome.	Sallam KI, Tamura N, Imoto N, Tamura T.	Appl Environ Microbiol	10.1128/aem.02131-09	2010
Metabolism	Bacterial steroid hydroxylases: enzyme classes, their functions and comparison of their catalytic mechanisms.	Szaleniec M, Wojtkiewicz AM, Bernhardt R, Borowski T, Donova M.	Appl Microbiol Biotechnol	10.1007/s00253-018-9239-3	2018
Metabolism	An inducible cytochrome P450 3A4-dependent vitamin D catabolic pathway.	Wang Z, Lin YS, Zheng XE, Senn T, Hashizume T, Scian M, Dickmann LJ, Nelson SD, Baillie TA, Hebert MF, Blough D, Davis CL, Thummel KE.	Mol Pharmacol	10.1124/mol.111.076356	2012
Genetics	Genome-Based Taxonomic Classification of the Phylum Actinobacteria.	Nouioui I, Carro L, Garcia-Lopez M, Meier-Kolthoff JP, Woyke T, Kyrpides NC, Pukall R, Klenk HP, Goodfellow M, Goker M.	Front Microbiol	10.3389/fmicb.2018.02007	2018
Genetics	Complete Genome Sequence of an Efficient Vitamin D3-Hydroxylating Bacterium, Pseudonocardia autotrophica NBRC 12743.	Yoshida K, Yasutake Y, Tamura T	Microbiol Resour Announc	10.1128/MRA.01105-18	2018
Genetics	Draft Genome Sequences of Three Actinobacteria Strains Presenting New Candidate Organisms with High Potentials for Specific P450 Cytochromes.	Grumaz C, Vainshtein Y, Kirstahler P, Luetz S, Kittelmann M, Schroer K, Eggimann FK, Czaja R, Vogel A, Hilberath T, Worsch A, Girhard M, Urlacher VB, Sandberg M, Sohn K	Genome Announc	10.1128/genomeA.00532-17	2017
Enzymology	Construction of a novel expression vector in Pseudonocardia autotrophica and its application to efficient biotransformation of compactin to pravastatin, a specific HMG-CoA reductase inhibitor.	Fujii Y, Norihisa K, Fujii T, Aritoku Y, Kagawa Y, Sallam KI, Johdo O, Arisawa A, Tamura T	Biochem Biophys Res Commun	10.1016/j.bbrc.2010.12.013	2010
Enzymology	Purification, characterization, and directed evolution study of a vitamin D3 hydroxylase from Pseudonocardia autotrophica.	Fujii Y, Kabumoto H, Nishimura K, Fujii T, Yanai S, Takeda K, Tamura N, Arisawa A, Tamura T	Biochem Biophys Res Commun	10.1016/j.bbrc.2009.05.033	2009
Metabolism	A gene cluster for the fatty acid catabolism from Pseudonocardia autotrophica BCRC12444.	Chen CH, Cheng JC, Cho YC, Hsu WH	Biochem Biophys Res Commun	10.1016/j.bbrc.2005.02.052	2005
Phylogeny	Pseudonocardia ammonioxydans sp. nov., isolated from coastal sediment.	Liu ZP, Wu JF, Liu ZH, Liu SJ.	Int J Syst Evol Microbiol	10.1099/ijs.0.63878-0	2006
Phylogeny	Pseudonocardia kongjuensis sp. nov., isolated from a gold mine cave.	Lee SD, Kim ES, Min KL, Lee WY, Kang SO, Hah YC.	Int J Syst Evol Microbiol	10.1099/00207713-51-4-1505	2001
Phylogeny	Pseudonocardia nantongensis sp. nov., a novel endophytic actinomycete isolated from the coastal halophyte Tamarix chinensis Lour.	Xing K, Qin S, Bian GK, Zhang YJ, Zhang WD, Dai CC, Liu CH, Li WJ, Jiang JH	Antonie Van Leeuwenhoek	10.1007/s10482-012-9764-5	2012
Phylogeny	Pseudonocardia endophytica sp. nov., isolated from the pharmaceutical plant Lobelia clavata.	Chen HH, Qin S, Li J, Zhang YQ, Xu LH, Jiang CL, Kim CJ, Li WJ	Int J Syst Evol Microbiol	10.1099/ijs.0.64740-0	2009

References

#130	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 535
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#33085	; Curators of the CIP;
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#66794	Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg: BRENDA, the ELIXIR core data resource in 2021: new developments and updates. Nucleic Acids Res. 49: D498 - D508 2020 ( DOI 10.1093/nar/gkaa1025 , PubMed 33211880 )
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68371	Automatically annotated from API 50CH acid .
#68382	Automatically annotated from API zym .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#116652	Collection of Institut Pasteur ; Curators of the CIP; CIP 107114
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Pseudonocardia autotrophica (DSM 535, ATCC 19727, CBS 466.68)

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