Streptomyces leeuwenhoekii C34 is a mesophilic prokaryote that produces antibiotic compounds and was isolated from hyper-arid desert soil.
antibiotic compound production mesophilic genome sequence 16S sequence| @ref 20215 |
Last LPSN update
2025-12-16 10:01:04 |
| Domain Bacillati |
| Phylum Actinomycetota |
| Class Actinomycetes |
| Order Kitasatosporales |
| Family Streptomycetaceae |
| Genus Streptomyces |
| Species Streptomyces leeuwenhoekii |
| Full scientific name Streptomyces leeuwenhoekii Busarakam et al. 2014 |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 21953 | GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) | Medium recipe at MediaDive  | Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 18.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water |
| @ref | Growth | Type | Temperature (°C) | Range | |
|---|---|---|---|---|---|
| 21953 | positive | growth | 28 | mesophilic |
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | IMG accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|---|
| 66792 | sleC34 assembly for Streptomyces leeuwenhoekii C34 (= DSM 42122 = NRRL B-24963) | complete | GCA_001013905   | 1437453.6  | 2872922060  | 1437453 | 98.84 |  |
| 66792 | StrepLeeu1.0 assembly for Streptomyces leeuwenhoekii C34 | scaffold | GCA_000696595 | 1437453.3 | 2582581028 | 1437453 | |
| @ref | Description | Accession | Length | Database | NCBI tax ID | |
|---|---|---|---|---|---|---|
| 21953 | Streptomyces leeuwenhoekii 16S ribosomal RNA gene, partial sequence | KF733382 | 1416 | | 1437453 |
| @ref | GC-content (mol%) | Method | |
|---|---|---|---|
| 21953 | 72.6 | high performance liquid chromatography (HPLC) |
| Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|
| First draft genome sequence data of TA4-1, the type strain of Gram-positive bacterium Streptomyces chiangmaiensis. | Yasawong M, Rosyidah A, Songngamsuk T, Phatcharaharikarn M, Ganta P, Chanthasena P, Chudapongse N, Santapan N, Srisakvarangkool W, Kerdtoob S, Nantapong N. | Data Brief | 10.1016/j.dib.2024.110611 | 2024 | |
| Mini review: Genome mining approaches for the identification of secondary metabolite biosynthetic gene clusters in Streptomyces. | Lee N, Hwang S, Kim J, Cho S, Palsson B, Cho BK. | Comput Struct Biotechnol J | 10.1016/j.csbj.2020.06.024 | 2020 | |
| Identification and Heterologous Expression of the Chaxamycin Biosynthesis Gene Cluster from Streptomyces leeuwenhoekii. | Castro JF, Razmilic V, Gomez-Escribano JP, Andrews B, Asenjo JA, Bibb MJ. | Appl Environ Microbiol | 10.1128/aem.01039-15 | 2015 | |
| Next Generation Sequencing of Actinobacteria for the Discovery of Novel Natural Products. | Gomez-Escribano JP, Alt S, Bibb MJ. | Mar Drugs | 10.3390/md14040078 | 2016 | |
| Recombinant Expression and Characterization of a Novel Type I Baeyer-Villiger Monooxygenase from a Streptomyces Strain Isolated from the Rhizosphere of the Atacama Desert Lupinus oreophilus. | Gonzalez C, Rodriguez S, Reyes-Godoy JP, Razmilic V, Martinez I. | Int J Mol Sci | 10.3390/ijms26135940 | 2025 | |
| Streptomyces small laccase expressed in Aspergillus Niger as a new addition for the lignocellulose bioconversion toolbox. | Sidar A, Voshol GP, El-Masoudi A, Vijgenboom E, Punt PJ. | Fungal Biol Biotechnol | 10.1186/s40694-024-00181-6 | 2024 | |
| A myo-inositol dehydrogenase involved in aminocyclitol biosynthesis of hygromycin A. | Akintubosun MO, Higgins MA. | Beilstein J Org Chem | 10.3762/bjoc.20.51 | 2024 | |
| The 'gifted' actinomycete Streptomyces leeuwenhoekii. | Castro JF, Razmilic V, Gomez-Escribano JP, Andrews B, Asenjo J, Bibb M. | Antonie Van Leeuwenhoek | 10.1007/s10482-018-1034-8 | 2018 | |
| Karakum desert: a unique source of cultivable novel and rare actinomycetes with a remarkable biosynthetic potential. | Saygin H, Sahin N, Goodfellow M. | World J Microbiol Biotechnol | 10.1007/s11274-025-04399-3 | 2025 | |
| Targeted Isolation of N-Acetylcysteine-Containing Angucycline Derivatives from Streptomyces sp. MC16 and Their Antiproliferative Effects. | Kim JG, Lee B, Han JS, Oh T, Park B, Cho YB, An BK, Choi JW, Ko SK, Lee MK, Hong YS, Hwang BY. | ACS Omega | 10.1021/acsomega.3c04647 | 2023 | |
| Secondary metabolites with antimicrobial activity produced by thermophilic bacteria from a high-altitude hydrothermal system. | Pardo-Este C, Cortes J, Castro-Severyn J, Perez V, Henriquez-Aedo K, Cuadros F, Yanez C, Cuadros-Orellana S, Dorador C, Molina V, Eissler Y, Paquis P, Jeffrey WH, Pozo P, Perez PA, Hengst MB. | Front Microbiol | 10.3389/fmicb.2024.1477458 | 2024 | |
| Heterologous Expression of a Cryptic Gene Cluster from Streptomyces leeuwenhoekii C34T Yields a Novel Lasso Peptide, Leepeptin. | Gomez-Escribano JP, Castro JF, Razmilic V, Jarmusch SA, Saalbach G, Ebel R, Jaspars M, Andrews B, Asenjo JA, Bibb MJ. | Appl Environ Microbiol | 10.1128/aem.01752-19 | 2019 | |
| Mining the Genome of Streptomyces leeuwenhoekii: Two New Type I Baeyer-Villiger Monooxygenases From Atacama Desert. | Gran-Scheuch A, Trajkovic M, Parra L, Fraaije MW. | Front Microbiol | 10.3389/fmicb.2018.01609 | 2018 | |
| Identification of Putative Drug Targets in Highly Resistant Gram-Negative Bacteria; and Drug Discovery Against Glycyl-tRNA Synthetase as a New Target. | Fereshteh S, Noori Goodarzi N, Kalhor H, Rahimi H, Barzi SM, Badmasti F. | Bioinform Biol Insights | 10.1177/11779322231152980 | 2023 | |
| Dual Induction of New Microbial Secondary Metabolites by Fungal Bacterial Co-cultivation. | Wakefield J, Hassan HM, Jaspars M, Ebel R, Rateb ME. | Front Microbiol | 10.3389/fmicb.2017.01284 | 2017 | |
| Bioaugmentation failed to enhance oil bioremediation in three soil samples from three different continents. | Radwan SS, Al-Mailem DM, Kansour MK. | Sci Rep | 10.1038/s41598-019-56099-2 | 2019 | |
| The Streptomyces leeuwenhoekii genome: de novo sequencing and assembly in single contigs of the chromosome, circular plasmid pSLE1 and linear plasmid pSLE2. | Gomez-Escribano JP, Castro JF, Razmilic V, Chandra G, Andrews B, Asenjo JA, Bibb MJ. | BMC Genomics | 10.1186/s12864-015-1652-8 | 2015 | |
| Induction of Cryptic Antifungal Pulicatin Derivatives from Pantoea agglomerans by Microbial Co-Culture. | Thissera B, Alhadrami HA, Hassan MHA, Hassan HM, Bawazeer M, Yaseen M, Belbahri L, Rateb ME, Behery FA. | Biomolecules | 10.3390/biom10020268 | 2020 | |
| Characterization of Yuhushiella sp. TD-032 from the Thar Desert and its antimicrobial activity. | Ibeyaima A, Rana J, Dwivedi A, Gupta S, Sharma SK, Saini N, Sarethy IP. | J Adv Pharm Technol Res | 10.4103/2231-4040.177201 | 2016 | |
| A Bifunctional Leader Peptidase/ABC Transporter Protein Is Involved in the Maturation of the Lasso Peptide Cochonodin I from Streptococcus suis. | Hegemann JD, Jeanne Dit Fouque K, Santos-Fernandez M, Fernandez-Lima F. | J Nat Prod | 10.1021/acs.jnatprod.1c00514 | 2021 | |
| Desert Environments Facilitate Unique Evolution of Biosynthetic Potential in Streptomyces. | Sivakala KK, Gutierrez-Garcia K, Jose PA, Thinesh T, Anandham R, Barona-Gomez F, Sivakumar N. | Molecules | 10.3390/molecules26030588 | 2021 | |
| Synthetic bacterial community derived from a desert rhizosphere confers salt stress resilience to tomato in the presence of a soil microbiome. | Schmitz L, Yan Z, Schneijderberg M, de Roij M, Pijnenburg R, Zheng Q, Franken C, Dechesne A, Trindade LM, van Velzen R, Bisseling T, Geurts R, Cheng X. | ISME J | 10.1038/s41396-022-01238-3 | 2022 | |
| Cas12a-assisted precise targeted cloning using in vivo Cre-lox recombination. | Enghiad B, Huang C, Guo F, Jiang G, Wang B, Tabatabaei SK, Martin TA, Zhao H. | Nat Commun | 10.1038/s41467-021-21275-4 | 2021 | |
| Aspergillus flavus Growth Inhibition and Aflatoxin B1 Decontamination by Streptomyces Isolates and Their Metabolites. | Campos-Avelar I, Colas de la Noue A, Durand N, Cazals G, Martinez V, Strub C, Fontana A, Schorr-Galindo S. | Toxins (Basel) | 10.3390/toxins13050340 | 2021 | |
| Actinobacterial Rare Biospheres and Dark Matter Revealed in Habitats of the Chilean Atacama Desert. | Idris H, Goodfellow M, Sanderson R, Asenjo JA, Bull AT. | Sci Rep | 10.1038/s41598-017-08937-4 | 2017 | |
| Actinobacteria Isolated from an Underground Lake and Moonmilk Speleothem from the Biggest Conglomeratic Karstic Cave in Siberia as Sources of Novel Biologically Active Compounds. | Axenov-Gribanov DV, Voytsekhovskaya IV, Tokovenko BT, Protasov ES, Gamaiunov SV, Rebets YV, Luzhetskyy AN, Timofeyev MA. | PLoS One | 10.1371/journal.pone.0149216 | 2016 | |
| C-S bond cleavage by a polyketide synthase domain. | Ma M, Lohman JR, Liu T, Shen B. | Proc Natl Acad Sci U S A | 10.1073/pnas.1508437112 | 2015 | |
| Actinobacteria Derived from Algerian Ecosystems as a Prominent Source of Antimicrobial Molecules. | Djinni I, Defant A, Kecha M, Mancini I. | Antibiotics (Basel) | 10.3390/antibiotics8040172 | 2019 | |
| Deciphering a Cyclodipeptide Synthase Pathway Encoding Prenylated Indole Alkaloids in Streptomyces leeuwenhoekii. | Zhang Y, Yao T, Jiang Y, Li H, Yuan W, Li W | Appl Environ Microbiol | 10.1128/AEM.02525-20 | 2021 | |
| Identification of four novel Streptomyces isolated from machair grassland soil using a culture-based bioprospecting strategy: Streptomyces caledonius sp. nov., Streptomyces machairae sp. nov., Streptomyces pratisoli sp. nov. and Streptomyces achmelvichensis sp. nov. | Prole JR, Allenby N, Manning DAC, Goodfellow M. | Int J Syst Evol Microbiol | 10.1099/ijsem.0.006736 | 2025 | |
| Streptomyces harenosi sp. nov., a home for a gifted strain isolated from Indonesian sand dune soil. | Kusuma AB, Nouioui I, Klenk HP, Goodfellow M. | Int J Syst Evol Microbiol | 10.1099/ijsem.0.004346 | 2020 | |
| Actinospica acidithermotolerans sp. nov., a novel actinomycete isolated from sediment from an Indonesian hot spring. | Kusuma AB, Putra KE, Vanggy LR, Loh J, Nouioui I, Goodfellow M. | Arch Microbiol | 10.1007/s00203-022-03058-7 | 2022 | |
| Streptomyces asenjonii sp. nov., isolated from hyper-arid Atacama Desert soils and emended description of Streptomyces viridosporus Pridham et al. 1958. | Goodfellow M, Busarakam K, Idris H, Labeda DP, Nouioui I, Brown R, Kim BY, Del Carmen Montero-Calasanz M, Andrews BA, Bull AT. | Antonie Van Leeuwenhoek | 10.1007/s10482-017-0886-7 | 2017 | |
| Streptomyces alkalithermotolerans sp. nov., a novel alkaliphilic and thermotolerant actinomycete isolated from a soda lake. | Sultanpuram VR, Mothe T, Mohammed F | Antonie Van Leeuwenhoek | 10.1007/s10482-014-0332-z | 2014 | |
| Streptomyces leeuwenhoekii sp. nov., the producer of chaxalactins and chaxamycins, forms a distinct branch in Streptomyces gene trees. | Busarakam K, Bull AT, Girard G, Labeda DP, van Wezel GP, Goodfellow M | Antonie Van Leeuwenhoek | 10.1007/s10482-014-0139-y | 2014 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive130720.20251217.10
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
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