Name: Cutibacterium acnes LMG 16711
Creator: BacDive
License: http://creativecommons.org/licenses/by-nc/4.0/

Strain identifier

BacDive ID: 12636

Type strain:

Species: Cutibacterium acnes

Culture col. no.: LMG 16711, DSM 1897, ATCC 6919, CCUG 1794, JCM 6425, KCTC 3314, NCTC 737, BCRC 10723, CECT 5684, CGMCC 1.5003, CIP 53.117, KCTC 5008, LMG 3591, NBRC 107605, NRRL B-4224, VKM Ac-1450, VPI 0389

Strain history: CIP <- 1953, NCTC <- F. Hayden, London, UK

NCBI tax ID(s): 1747 (species)

SI-ID 389260

LMG 3591, ATCC 6919, CCRC 10723, CCUG 1794, DSM 1897, JCM 6425, LMG 16711, NCTC 737, VKM Ac-1450, CIP 53.117, KCTC 3314, KCTC 5008, AS 1.5003, NRRL B-4224, BCRC 10723, CCT 2592, CECT 5684, CGMCC 1.5003

Other strains from Cutibacterium acnes

Section

Cutibacterium acnes LMG 16711 is an anaerobe, mesophilic, Gram-positive bacterium that was isolated from acne lesion in human facial skin.

Gram-positive
rod-shaped
anaerobe
mesophilic
16S sequence
Bacteria
genome sequence

Information on the name and the taxonomic classification. Name and taxonomic classification

	Last LPSN update	14-12-2023 (DD-MM-YYYY)
	Domain	"Bacteria"
	Phylum	*Actinomycetota*
	Class	*Actinomycetes*
	Order	*Propionibacteriales*
	Family	*Propionibacteriaceae*
	Genus	*Cutibacterium*
	Species	**Cutibacterium acnes**
	Full Scientific Name (LPSN)	Cutibacterium acnes (Gilchrist 1900) Scholz and Kilian 2016

	Synonym	"Bacillus* acnes"*
	Synonym	Propionibacterium acnes

Information on morphological and physiological properties Morphology

[Ref.: #24963]	Gram stain	positive
[Ref.: #116031]	Gram stain	positive
[Ref.: #69480]	Gram stain	positive Confidence in %100

[Ref.: #24963]	Cell length	0.8-0.9 µm

[Ref.: #24963]	Cell width	0.4-0.5 µm

[Ref.: #24963]	Cell shape	rod-shaped
[Ref.: #116031]	Cell shape	rod-shaped
[Ref.: #24963]	Cell shape	ellipsoidal

[Ref.: #24963]	Motility	no
[Ref.: #116031]	Motility	no
[Ref.: #69480]	Motility	no Confidence in %94.971

[Ref.: #24963]	Type of hemolysis	beta
[Ref.: #24963]	Hemolysis ability	1
[Ref.: #24963]	Colony size	<4.0 mm
[Ref.: #24963]	Colony color	white,tan, pink or orange
[Ref.: #24963]	Incubation period	21 days

[Ref.: #24963]	Type of hemolysis	beta
[Ref.: #24963]	Hemolysis ability	1
[Ref.: #24963]	Colony size	<5.0 mm
[Ref.: #24963]	Colony color	white-to-gray
[Ref.: #24963]	Colony shape	circular
[Ref.: #24963]	Cultivation medium used	blood agar (horse or rabbit)

[Ref.: #44423]	Incubation period	2-3 days

Information on culture and growth conditions Culture and growth conditions

[Ref.: #919]

Culture medium

COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)

[Ref.: #919]

Culture medium growth

[Ref.: #919]

Culture medium link

Medium recipe at MediaDive

[Ref.: #919]

Culture medium composition

expand / minimize

[Ref.: #919]

Culture medium

PYG MEDIUM (MODIFIED) (DSMZ Medium 104)

[Ref.: #919]

Culture medium growth

[Ref.: #919]

Culture medium link

Medium recipe at MediaDive

[Ref.: #919]

Culture medium composition

expand / minimize

[Ref.: #24963]

Culture medium

blood agar (horse or rabbit)

[Ref.: #24963]

Culture medium growth

[Ref.: #42199]

Culture medium

MEDIUM 20 - for Anaerobic bacteria

[Ref.: #42199]

Culture medium growth

[Ref.: #42199]

Culture medium composition

expand / minimize

[Ref.: #116031]

Culture medium

CIP Medium 20

[Ref.: #116031]

Culture medium growth

[Ref.: #116031]

Culture medium link

Medium recipe provided by DSMZ

		Temperature
[Ref.: #919]	growth	37 °C
[Ref.: #24963]	optimum	30.0-37.0 °C
[Ref.: #42199]	growth	37 °C
[Ref.: #44423]	growth	37 °C
[Ref.: #67770]	growth	37 °C

[Ref.: #919]	Temperature range	mesophilic
[Ref.: #24963]	Temperature range	mesophilic
[Ref.: #42199]	Temperature range	mesophilic
[Ref.: #44423]	Temperature range	mesophilic
[Ref.: #67770]	Temperature range	mesophilic

	pH	Kind of pH		pH
[Ref.: #24963]			maximum	4.5-5.0

Information on physiology and metabolism Physiology and metabolism

[Ref.: #919]	Oxygen tolerance	anaerobe
[Ref.: #24963]	Oxygen tolerance	anaerobe
[Ref.: #24963]	Oxygen tolerance	aerotolerant
[Ref.: #44423]	Oxygen tolerance	anaerobe
[Ref.: #116031]	Oxygen tolerance	anaerobe

[Ref.: #24963]	Ability of spore formation	no
[Ref.: #69481]	Ability of spore formation	no Confidence in %100
[Ref.: #69480]	Ability of spore formation	no Confidence in %99.993

[Ref.: #919]

Name of produced compound

LL diaminopimelic acid

[Ref.: #919]	Murein short key	A41.01
[Ref.: #919]	Murein types	A3gamma LL-Dpm-Gly

	Metabolite	Utilization activity	Kind of utilization tested
[Ref.: #24963]	esculin ChEBI	-	hydrolysis
[Ref.: #116031]	esculin ChEBI	-	hydrolysis
[Ref.: #24963]	gelatin ChEBI	+	hydrolysis
[Ref.: #24963]	glucose ChEBI	+	fermentation
[Ref.: #24963]	glycerol ChEBI	+	fermentation
[Ref.: #68380]	L-glutamate ChEBI	-	degradation	* from API rID32A
[Ref.: #24963]	maltose ChEBI	-	fermentation
[Ref.: #24963]	nitrate ChEBI	+	reduction
[Ref.: #116031]	nitrate ChEBI	+	reduction
[Ref.: #116031]	nitrite ChEBI	-	reduction
[Ref.: #68380]	raffinose ChEBI	-	fermentation	* from API rID32A
[Ref.: #24963]	ribose ChEBI	-	fermentation
[Ref.: #24963]	sorbitol ChEBI	+	fermentation
[Ref.: #24963]	sucrose ChEBI	-	fermentation
[Ref.: #68380]	tryptophan ChEBI	+	energy source	* from API rID32A
[Ref.: #68380]	urea ChEBI	-	hydrolysis	* from API rID32A
	Only first 10 entries are displayed. Click here to see all.

	Metabolite	Production
[Ref.: #24963]	indole ChEBI	yes
[Ref.: #116031]	indole ChEBI	yes
[Ref.: #68380]	indole ChEBI	yes	* from API rID32A

	Physiological tests	Metabolite	Voges-Proskauer-test	Indole test
[Ref.: #116031]		acetoin ChEBI	-
[Ref.: #68380]		indole ChEBI		+	* from API rID32A

	Enzyme	Enzyme activity	EC number
[Ref.: #24963]	acid phosphatase	+	3.1.3.2
[Ref.: #68382]	acid phosphatase	+	3.1.3.2	* from API zym
[Ref.: #68380]	alanine arylamidase	+	3.4.11.2	* from API rID32A
[Ref.: #68380]	alkaline phosphatase	-	3.1.3.1	* from API rID32A, API zym
[Ref.: #68380]	alpha-arabinosidase	-	3.2.1.55	* from API rID32A
[Ref.: #68382]	alpha-chymotrypsin	-	3.4.21.1	* from API zym
[Ref.: #68380]	alpha-fucosidase	-	3.2.1.51	* from API rID32A, API zym
[Ref.: #68380]	alpha-galactosidase	-	3.2.1.22	* from API rID32A, API zym
[Ref.: #68382]	alpha-glucosidase	+	3.2.1.20	* from API zym
[Ref.: #68380]	alpha-glucosidase	-	3.2.1.20	* from API rID32A
[Ref.: #68382]	alpha-mannosidase	-	3.2.1.24	* from API zym
[Ref.: #116031]	amylase	-
[Ref.: #116031]	beta-galactosidase	-	3.2.1.23
[Ref.: #68382]	beta-galactosidase	+	3.2.1.23	* from API zym
[Ref.: #68380]	beta-Galactosidase 6-phosphate	-		* from API rID32A
[Ref.: #68380]	beta-glucosidase	-	3.2.1.21	* from API rID32A, API zym
[Ref.: #68380]	beta-glucuronidase	-	3.2.1.31	* from API rID32A, API zym
[Ref.: #116031]	caseinase	+	3.4.21.50
[Ref.: #24963]	catalase	+	1.11.1.6
[Ref.: #116031]	catalase	+	1.11.1.6
[Ref.: #68382]	cystine arylamidase	-	3.4.11.3	* from API zym
[Ref.: #116031]	DNase	-
[Ref.: #68382]	esterase (C 4)	+		* from API zym
[Ref.: #68382]	esterase lipase (C 8)	-		* from API zym
[Ref.: #116031]	gelatinase	-
[Ref.: #68380]	glutamate decarboxylase	-	4.1.1.15	* from API rID32A
[Ref.: #68380]	glutamyl-glutamate arylamidase	-		* from API rID32A
[Ref.: #68380]	glycin arylamidase	+		* from API rID32A
[Ref.: #68380]	histidine arylamidase	-		* from API rID32A
[Ref.: #24963]	hyaluronidase	+	3.2.1.35
[Ref.: #24963]	lecithinase	+
[Ref.: #116031]	lecithinase	+
[Ref.: #68382]	leucine arylamidase	+	3.4.11.1	* from API zym
[Ref.: #68380]	leucine arylamidase	-	3.4.11.1	* from API rID32A
[Ref.: #24963]	lipase	+
[Ref.: #116031]	lipase	+
[Ref.: #68382]	lipase (C 14)	-		* from API zym
[Ref.: #68382]	N-acetyl-beta-glucosaminidase	+	3.2.1.52	* from API zym
[Ref.: #68382]	naphthol-AS-BI-phosphohydrolase	+		* from API zym
[Ref.: #24963]	neuramindase	+	3.2.1.18
[Ref.: #116031]	oxidase	-
[Ref.: #68380]	phenylalanine arylamidase	-		* from API rID32A
[Ref.: #68380]	proline-arylamidase	+	3.4.11.5	* from API rID32A
[Ref.: #116031]	protease	-
[Ref.: #24963]	pyrrolidonyl arylamidase	+	3.4.19.3
[Ref.: #68380]	pyrrolidonyl arylamidase	-	3.4.19.3	* from API rID32A
[Ref.: #24963]	ribonuclease	+	2.7.7.16
[Ref.: #68382]	trypsin	-	3.4.21.4	* from API zym
[Ref.: #68380]	tryptophan deaminase	+	4.1.99.1	* from API rID32A
[Ref.: #116031]	tween esterase	-
[Ref.: #68380]	tyrosine arylamidase	-		* from API rID32A
[Ref.: #116031]	urease	-	3.5.1.5
[Ref.: #68380]	urease	-	3.5.1.5	* from API rID32A
[Ref.: #68382]	valine arylamidase	-		* from API zym
	Only first 10 entries are displayed. Click here to see all.

API® Biotype100:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	ControlQ	D-glucose as carbon sourceGLU	D-fructose as carbon sourceFRU	D-galactose as carbon sourceGAL	D-trehalose as carbon sourceTRE	D-mannose as carbon sourceMNE	L-sorbose as carbon sourceSBE	D-melibiose as carbon sourceMEL	sucrose as carbon sourceSAC	D-raffinose as carbon sourceRAF	maltotriose as carbon sourceMTE	maltose as carbon sourceMAL	lactose as carbon sourceLAC	lactulose as carbon sourceLTE	1-O-methyl-beta-galactopyranoside as carbon sourceMbGa	1-O-methyl-alpha-galactopyranoside as carbon sourceMaGa	D-cellobiose as carbon sourceCEL	gentiobiose as carbon sourceGEN	1-O-methyl-beta-D-glucopyranoside as carbon sourceMbGu	esculin as carbon sourceESC	D-ribose as carbon sourceRIB	L-arabinose as carbon sourceARA	D-xylose as carbon sourceXYL	palatinose as carbon sourcePLE	L-rhamnose as carbon sourceRHA	L-fucose as carbon sourceFUC	D-melezitose as carbon sourceMLZ	D-arabitol as carbon sourceDARL	L-arabitol as carbon sourceLARL	xylitol as carbon sourceXLT	dulcitol as carbon sourceDUL	D-tagatose as carbon sourceTAG	glycerol as carbon sourceGLY	myo-inositol as carbon sourceINO	D-mannitol as carbon sourceMAN	maltitol as carbon sourceMTL	D-turanose as carbon sourceTUR	D-sorbitol as carbon sourceSOR	adonitol as carbon sourceADO	hydroxyquinoline-beta-glucuronide as carbon sourceHBG	D-lyxose as carbon sourceLYX	i-erythritol as carbon sourceERY	1-O-methyl-alpha-D-glucoside as carbon sourceMDG	3-O-methyl-D-glucose as carbon source3MDG	D-saccharate as carbon sourceSAT	mucate as carbon sourceMUC	L-tartrate as carbon sourceLTAT	D-tartrate as carbon sourceDTAT	meso-tartrate as carbon sourceMTAT	D-malate as carbon sourceDMLT	L-malate as carbon sourceLMLT	cis-aconitate as carbon sourceCATE	trans-aconitate as carbon sourceTATE	tricarballylate as carbon sourceTTE	citrate as carbon sourceCIT	D-glucuronate as carbon sourceGRT	D-galacturonate as carbon sourceGAT	2-ketogluconate as carbon source2KG	5-ketogluconate as carbon source5KG	tryptophan as carbon sourceTRY	N-acetyl-D-glucosamine as carbon sourceNAG	D-gluconate as carbon sourceGNT	phenylacetate as carbon sourcePAC	protocatechuate as carbon sourcePAT	4-hydroxybenzoate as carbon sourcepOBE	quinate as carbon sourceQAT	gentisate as carbon sourceGTE	3-hydroxybenzoate as carbon sourcemOBE	benzoate as carbon sourceBAT	3-phenylpropionate as carbon sourcePPAT	m-coumarate as carbon sourceCMT	trigonelline as carbon sourceTGE	betaine as carbon sourceBET	putrescine as carbon sourcePCE	4-aminobutyrate as carbon sourceABT	histamine as carbon sourceHIN	DL-lactate as carbon sourceLAT	caprate as carbon sourceCAP	caprylate as carbon sourceCYT	L-histidine as carbon sourceHIS	succinate as carbon sourceSUC	fumarate as carbon sourceFUM	glutarate as carbon sourceGRE	DL-glycerate as carbon sourceGYT	5-aminovalerate as carbon sourceAVT	ethanolamine as carbon sourceETN	tryptamine as carbon sourceTTN	D-glucosamine as carbon sourceGLN	itaconate as carbon sourceITA	3-hydroxybutyrate as carbon source3OBU	L-aspartate as carbon sourceAPT	L-glutamate as carbon sourceGTT	L-proline as carbon sourcePRO	D-alanine as carbon sourceDALA	L-alanine as carbon sourceLALA	L-serine as carbon sourceSER	malonate as carbon sourceMNT	propionate as carbon sourcePROP	L-tyrosine as carbon sourceTYR	2-ketoglutarate as carbon source2KT
[Ref.: #116031]	3004	not determinedn.d.	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-

API® rID32A:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	Urease/urea hydrolysisURE	Arginine dihydrolaseADH (Arg)	alpha-Galactosidasealpha GAL	beta-Galactosidasebeta GAL	beta-Galactosidase 6-phosphatebeta GP	alpha-Glucosidasealpha GLU	beta-Glucosidasebeta GLU	alpha-Arabinosidasealpha ARA	beta-Glucuronidasebeta GUR	beta-N-Acetyl-beta-glucosaminidasebeta NAG	Fermentation of D-mannoseMNE	Fermentation of raffinoseRAF	Glutamate decarboxylaseGDC	alpha-Fucosidasealpha FUC	Reduction of nitrateNIT	Indole productionIND	Alkaline phosphatasePAL	L-arginine arylamidaseArgA	Proline arylamidaseProA	Leucyl glycin arylamidaseLGA	Phenylalanine arylamidasePheA	Leucine arylamidaseLeuA	Pyrrolidonyl arylamidasePyrA	Tyrosine arylamidaseTyrA	Alanine arylamidaseAlaA	Glycin arylamidaseGlyA	Histidine arylamidaseHisA	Glutamyl-glutamate arylamidaseGGA	Serine arylamidaseSerA
[Ref.: #919]	13312	-	+	-	+	-	-	-	-	-	+	+	-	-	-	+	+	-	+	+	+/-	-	-	-	-	+	+	-	-	+
[Ref.: #919]	12523	-	+	-	+	-	-	-	-	-	+	+	-	-	-	+/-	+	-	-	+	-	-	-	-	-	+	+	-	-	+
[Ref.: #919]	12524	-	+	-	+	-	-	-	-	-	+	+	-	-	-	+	+	-	+	+	-	-	-	-	-	+	+	-	-	+
[Ref.: #919]	12525	-	-	-	+	-	-	-	-	-	+/-	+	-	-	-	+	+	-	-	+	-	-	-	-	-	+	+	-	-	+
[Ref.: #919]	12526	-	+	-	+	-	-	-	-	-	+	+	-	-	-	-	+	-	+/-	+	-	-	-	-	-	+	+	-	-	+
[Ref.: #919]	12527	-	+	-	+/-	-	-	-	-	-	+	+	-	-	-	+	+	-	-	+	-	-	-	-	-	+	+	-	-	+
[Ref.: #919]	12953	-	+	-	+	-	-	-	-	-	+	-	-	-	-	+	+	-	-	+	-	-	-	-	-	+	+	-	-	-
[Ref.: #919]	13033	-	+	-	+	-	-	-	-	-	+	+	-	-	-	+	+	-	-	+	-	-	-	-	-	+	+	-	-	+
[Ref.: #919]	13105	-	+	-	+	-	-	-	-	-	+	+	-	-	-	+	+	-	+	+	-	-	-	-	-	+	+	-	-	+
[Ref.: #919]	12522	-	+	-	+	-	-	-	-	-	+/-	+	-	-	-	+	+	-	+/-	+	-	-	-	-	-	+	+	-	-	+

API® zym:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	Control	2-naphthyl phosphateAlkaline phosphatase	2-naphthyl butyrateEsterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	2-naphthyl myristateLipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	N-benzoyl-DL-arginine-2-naphthylamideTrypsin	N-glutaryl-phenylalanine-2-naphthylamidealpha- Chymotrypsin	2-naphthyl phosphateAcid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	6-Br-2-naphthyl-alphaD-galactpyranosidealpha- Galactosidase	2-naphthyl-betaD-galactpyranosidebeta- Galactosidase	Naphthol-AS-BI-betaD-glucuronidebeta- Glucuronidase	2-naphthyl-alphaD-glucopyranosidealpha- Glucosidase	6-Br-2-naphthyl-betaD-glucopyranosidebeta- Glucosidase	1-naphthyl-N-acetyl-betaD-glucosaminideN-acetyl-beta- glucosaminidase	6-Br-2-naphthyl-alphaD-mannopyranosidealpha- Mannosidase	2-naphthyl-alphaL-fucopyranosidealpha- Fucosidase
[Ref.: #116031]	12691	-	-	+	-	-	+	-	-	-	-	+	+	-	+	-	+	-	+	-	-

Information on isolation source, the sampling and environmental conditions Isolation, sampling and environmental information

[Ref.: #919]	Sample type/isolated from	acne lesion in human facial skin

[Ref.: #24963]	Sample type/isolated from	facial acne
[Ref.: #24963]	Geographic location (country and/or sea, region)	London
[Ref.: #24963]	Country	United Kingdom
[Ref.: #24963]	Country ISO 3 Code	GBR
[Ref.: #24963]	Continent	Europe

[Ref.: #44423]	Sample type/isolated from	Human,facial acne
[Ref.: #44423]	Country	United Kingdom
[Ref.: #44423]	Country ISO 3 Code	GBR
[Ref.: #44423]	Continent	Europe

[Ref.: #67770]	Sample type/isolated from	Facial acne

[Ref.: #116031]	Sample type/isolated from	Facial acne
[Ref.: #116031]	Geographic location (country and/or sea, region)	London
[Ref.: #116031]	Country	United Kingdom
[Ref.: #116031]	Country ISO 3 Code	GBR
[Ref.: #116031]	Continent	Europe
[Ref.: #116031]	Isolation date	1920
* marker position based on {}

Isolation sources categories

#Host	#Human	-
#Infection	#Inflammation	-
#Host Body-Site	#Organ	#Skin, Nail, Hair

What are isolation sources categories?

[Ref.: #69479]

Global distribution of 16S sequence AB538431 (>99% sequence identity) for Cutibacterium acnes from Microbeatlas

Aquatic Samples	7473
Soil Samples	3573
Animal Samples	47966
Plant Samples	1257
Total Samples	60269

Information on possible application of the strain and its possible interaction with e.g. potential hosts Safety information

[Ref.: #919]	Biosafety level	2	Risk group (German classification) According to TRBA 466
[Ref.: #116031]	Biosafety level	1	Risk group (French classification)

Information on genomic background e.g. entries in nucleic sequence databass Sequence information

16S Sequence information:

Only first 5 entries are displayed. Click here to see all.

	Sequence accession description	Seq. accession number	Sequence length (bp)	Sequence database	Associated NCBI tax ID
[Ref.: #919]	Propionibacterium acnes gene for 16S ribosomal RNA, ATCC6919	AB042288	1486	ENA	1747 tax ID
[Ref.: #20218]	Propionibacterium acnes DNA, 16S-23S ribosomal RNA intergenic spacer region, strain: ATCC 6919	AB108459	222	ENA	1747 tax ID	*
[Ref.: #20218]	Propionibacterium acnes ATCC 6919 16S rRNA gene, partial sequence	U02904	387	ENA	1747 tax ID	*
[Ref.: #20218]	Propionibacterium acnes strain CCUG 1794 clone 1 16S-23S ribosomal RNA intergenic spacer, partial sequence	GQ496473	222	ENA	1747 tax ID	*
[Ref.: #20218]	Propionibacterium acnes strain DSM 1897 16S ribosomal RNA gene, partial sequence	EF680378	451	ENA	1747 tax ID	*
[Ref.: #20218]	Propionibacterium acnes partial 16S rRNA	X53218	1359	ENA	1747 tax ID	*
[Ref.: #20218]	Propionibacterium acnes gene for 16S ribosomal RNA, partial sequence, strain: JCM 6425	AB538431	1486	ENA	1747 tax ID	*

Genome sequence information:

Only first 5 entries are displayed. Click here to see all.

	Sequence accession description	Seq. accession number	Assembly level	Sequence database	Associated NCBI tax ID
[Ref.: #67770]	Cutibacterium acnes DSM 1897	GCA_000472405	contig	GenBank	1122995 tax ID
[Ref.: #66792]	Cutibacterium acnes ATCC 6919	GCA_008728435	complete	GenBank	1747 tax ID	*
[Ref.: #66792]	Cutibacterium acnes DSM 1897	GCA_004136195	complete	GenBank	1122995 tax ID	*
[Ref.: #66792]	Cutibacterium acnes subsp. acnes NBRC 107605	GCA_006739385	complete	GenBank	1734925 tax ID	*
[Ref.: #66792]	Cutibacterium acnes ATCC 6919	GCA_000730485	contig	GenBank	1747 tax ID	*
[Ref.: #66792]	Cutibacterium acnes DSM 1897	1122995.5	complete	PATRIC	1122995 tax ID	*

[Ref.: #919]	GC-content	59.0 mol%
[Ref.: #24963]	GC-content	60 mol%	genome sequence analysis

Data predicted using genome information as a basis Genome-based predictions

	Trait	Prediction	Confidence in %	In training data
	Predictions from GenomeNet Sporulation v. 1 based on: Cutibacterium acnes DSM 1897 PATRIC: 1122995.5
[Ref.: #69481]	spore-forming	no	100	no

	Trait	Prediction	Confidence in %	In training data
	Predictions from Diaspora project based on: Cutibacterium acnes ATCC 6919 NCBI: GCA_003030305.1
[Ref.: #69480]	flagellated	no	98.303	yes
[Ref.: #69480]	gram-positive	yes	92.505	yes
[Ref.: #69480]	anaerobic	yes	59.016	no
[Ref.: #69480]	halophile	no	85.4	no
[Ref.: #69480]	spore-forming	no	91.161	no
[Ref.: #69480]	glucose-util	yes	91.279	no
[Ref.: #69480]	aerobic	no	87.107	no
[Ref.: #69480]	thermophile	no	69.227	yes
[Ref.: #69480]	motile	no	94.255	yes
[Ref.: #69480]	glucose-ferment	yes	82.576	yes

Availability in culture collections External links

[Ref.: #919]

Culture collection no.

LMG 16711, DSM 1897, ATCC 6919, CCUG 1794, JCM 6425, KCTC 3314, NCTC 737, BCRC 10723, CECT 5684, CGMCC 1.5003, CIP 53.117, KCTC 5008, LMG 3591, NBRC 107605, NRRL B-4224, VKM Ac-1450, VPI 0389

[Ref.: #81849]

SI-ID 389260

Literature:

Only first 10 entries are displayed. Click here to see all.

	Title	Authors	Journal	DOI	Year
Cultivation	Coculture method for in vitro cultivation of uncultured oral bacteria.	Kusugal P, Bhat KG, Ingalagi P, Patil S, Pattar G	J Oral Maxillofac Pathol	10.4103/0973-029X.325125	2021	*
Pathogenicity	Interaction of implant infection-related commensal bacteria with mesenchymal stem cells: a comparison between Cutibacterium acnes and Staphylococcus aureus.	El-Mahdy TS, Mongaret C, Varin-Simon J, Lamret F, Vernet-Garnier V, Rammal H, Mauprivez C, Kerdjoudj H, Gangloff SC, Reffuveille F	FEMS Microbiol Lett	10.1093/femsle/fnab014	2021	*
Pathogenicity	Evaluation of tea tree oil physicochemical features and its antimicrobial activity against Cutibacterium acnes (Propionibacterium acnes) ATCC 6919	Ossa-Tabares JC, Llanos CJ, Garcia AM	Biomedica	10.7705/biomedica.5122	2020	*
Enzymology	Saponin fraction from Sapindus mukorossi Gaertn as a novel cosmetic additive: Extraction, biological evaluation, analysis of anti-acne mechanism and toxicity prediction.	Wei MP, Qiu JD, Li L, Xie YF, Yu H, Guo YH, Yao WR	J Ethnopharmacol	10.1016/j.jep.2020.113552	2020	*
Genetics	Complete Genome Sequences and Methylome Analyses of Cutibacterium acnes subsp. acnes Strains DSM 16379 and DSM 1897(T).	Deptula P, Laine P, Paulin L, Auvinen P, Roberts RJ, Johnston CD, Varmanen P	Microbiol Resour Announc	10.1128/MRA.00705-20	2020	*
Metabolism	Caenorhabditis elegans mounts a p38 MAPK pathway-mediated defence to Cutibacterium acnes infection.	Huang X, Pan W, Kim W, White A, Li S, Li H, Lee K, Fuchs BB, Zeng K, Mylonakis E	Cell Microbiol	10.1111/cmi.13234	2020	*
Pathogenicity	Rosa davurica Pall. Improves Propionibacterium acnes-Induced Inflammatory Responses in Mouse Ear Edema Model and Suppresses Pro-Inflammatory Chemokine Production via MAPK and NF-kappaB Pathways in HaCaT Cells.	Hwang DH, Lee DY, Koh PO, Yang HR, Kang C, Kim E	Int J Mol Sci	10.3390/ijms21051717	2020	*
Pathogenicity	Synthesis and evaluation of biological activity of benzoxaborole derivatives of azithromycin.	Tevyashova AN, Korolev AM, Mirchink EP, Isakova EB, Osterman IA	J Antibiot (Tokyo)	10.1038/s41429-018-0107-2	2018	*
Pathogenicity	Mikania glomerata Sprengel extract and its major compound ent-kaurenoic acid display activity against bacteria present in endodontic infections.	Moreti DLC, Leandro LF, da Silva Moraes T, Moreira MR, Sola Veneziani RC, Ambrosio SR, Gomes BP, Martins CHG	Anaerobe	10.1016/j.anaerobe.2017.06.008	2017	*
Pathogenicity	A Polycation Antimicrobial Peptide Mimic without Resistance Buildup against Propionibacterium Acnes.	Nair SS, Zolotarskaya OY, Beckwith MJ, Ohman DE, Wynne KJ	Macromol Biosci	10.1002/mabi.201700090	2017	*
Pathogenicity	N-acetylcysteine inhibits growth, adhesion and biofilm formation of Gram-positive skin pathogens.	Eroshenko D, Polyudova T, Korobov V	Microb Pathog	10.1016/j.micpath.2017.02.030	2017	*
Pathogenicity	Interaction of Cutibacterium ( formerly Propionibacterium) acnes with bone cells: a step toward understanding bone and joint infection development.	Aubin GG, Baud'huin M, Lavigne JP, Brion R, Gouin F, Lepelletier D, Jacqueline C, Heymann D, Asehnoune K, Corvec S	Sci Rep	10.1038/srep42918	2017	*
Proteome	Analysis of the Surface, Secreted, and Intracellular Proteome of Propionibacterium acnes.	Yu Y, Champer J, Kim J	EuPA Open Proteom	10.1016/j.euprot.2015.06.003	2015	*
Phylogeny	Emendation of Propionibacterium acnes subsp. acnes (Deiko et al. 2015) and proposal of Propionibacterium acnes type II as Propionibacterium acnes subsp. defendens subsp. nov.	McDowell A, Barnard E, Liu J, Li H, Patrick S	Int J Syst Evol Microbiol	10.1099/ijsem.0.001521	2016	*
Phylogeny	Propionibacterium namnetense sp. nov., isolated from a human bone infection.	Aubin GG, Bemer P, Kambarev S, Patel NB, Lemenand O, Caillon J, Lawson PA, Corvec S	Int J Syst Evol Microbiol	10.1099/ijsem.0.001204	2016	*
Pathogenicity	Chemical Composition of the Essential Oil from Croton oblongifolius and its Antibacterial Activity against Propionibacterium acnes.	Athikomkulchai S, Tadtong S, Ruangrungsi N, Hongratanaworakit T	Nat Prod Commun		2015	*
Phylogeny	Dissecting the taxonomic heterogeneity within Propionibacterium acnes: proposal for Propionibacterium acnes subsp. acnes subsp. nov. and Propionibacterium acnes subsp. elongatum subsp. nov.	Dekio I, Culak R, Misra R, Gaulton T, Fang M, Sakamoto M, Ohkuma M, Oshima K, Hattori M, Klenk HP, Rajendram D, Gharbia SE, Shah HN	Int J Syst Evol Microbiol	10.1099/ijsem.0.000648	2015	*
Pathogenicity	Antimicrobial photodynamic therapy using chlorin e6 with halogen light for acne bacteria-induced inflammation.	Jeon YM, Lee HS, Jeong D, Oh HK, Ra KH, Lee MY	Life Sci	10.1016/j.lfs.2014.12.029	2015	*
Genetics	Draft Genome Sequences of Propionibacterium acnes Type Strain ATCC6919 and Antibiotic-Resistant Strain HL411PA1.	Liu J, Cheng A, Bangayan NJ, Barnard E, Curd E, Craft N, Li H	Genome Announc	10.1128/genomeA.00740-14	2014	*
Metabolism	5alpha-Androst-16-en-3alpha-ol beta-D-glucuronide, precursor of 5alpha-androst-16-en-3alpha-ol in human sweat.	Starkenmann C, Mayenzet F, Brauchli R, Troccaz M	Chem Biodivers	10.1002/cbdv.201300286	2013	*
Pathogenicity	Evaluation of antibacterial and anti-inflammatory activities of less polar ginsenosides produced from polar ginsenosides by heat-transformation.	Wang L, Yang X, Yu X, Yao Y, Ren G	J Agric Food Chem	10.1021/jf404461q	2013	*
Pathogenicity	Protease-activated receptor-2 mediates the expression of inflammatory cytokines, antimicrobial peptides, and matrix metalloproteinases in keratinocytes in response to Propionibacterium acnes.	Lee SE, Kim JM, Jeong SK, Jeon JE, Yoon HJ, Jeong MK, Lee SH	Arch Dermatol Res	10.1007/s00403-010-1074-z	2010	*
Pathogenicity	Syntheses of carnosic acid and carnosol, anti-oxidants in Rosemary, from pisiferic acid, the major constituent of Sawara.	Tada M, Ohkanda T, Kurabe J	Chem Pharm Bull (Tokyo)	10.1248/cpb.58.27	2010	*
Metabolism	Involvement of Propionibacterium acnes in the augmentation of lipogenesis in hamster sebaceous glands in vivo and in vitro.	Iinuma K, Sato T, Akimoto N, Noguchi N, Sasatsu M, Nishijima S, Kurokawa I, Ito A	J Invest Dermatol	10.1038/jid.2009.46	2009	*
Enzymology	Cloning and expression of antibacterial goat lactoferricin from Escherichia coli AD494(DE3)pLysS expression system.	Chen GH, Yin LJ, Chiang IH, Jiang ST	J Food Prot	10.4315/0362-028x-71.12.2523	2008	*
Enzymology	Characterization of beta-1,3-galactosyl-N-acetylhexosamine phosphorylase from Propionibacterium acnes.	Nakajima M, Nishimoto M, Kitaoka M	Appl Microbiol Biotechnol	10.1007/s00253-008-1838-y	2009	*
Phylogeny	A new phylogenetic group of Propionibacterium acnes.	McDowell A, Perry AL, Lambert PA, Patrick S	J Med Microbiol	10.1099/jmm.0.47489-0	2008	*
Enzymology	Linoleic acid isomerase from Propionibacterium acnes: purification, characterization, molecular cloning, and heterologous expression.	Deng MD, Grund AD, Schneider KJ, Langley KM, Wassink SL, Peng SS, Rosson RA	Appl Biochem Biotechnol	10.1007/s12010-007-8075-1	2007	*
Pathogenicity	Biofilm formation of the pathogens of fatal bacterial granuloma after trauma: potential mechanism underlying the failure of traditional antibiotic treatments.	Qi X, Gao J, Sun D, Liang W, Wan Y, Li C, Xu X, Gao T	Scand J Infect Dis	10.1080/00365540701632998	2007	*
Pathogenicity	Effect of bacteriocin produced by Lactococcus sp. HY 449 on skin-inflammatory bacteria.	Oh S, Kim SH, Ko Y, Sim JH, Kim KS, Lee SH, Park S, Kim YJ	Food Chem Toxicol	10.1016/j.fct.2005.08.008	2006	*
Pathogenicity	Effect of bacteriocin produced by Lactococcus sp. HY 449 on skin-inflammatory bacteria.	Oh S, Kim SH, Ko Y, Sim JH, Kim KS, Lee SH, Park S, Kim YJ	Food Chem Toxicol	10.1016/j.fct.2005.08.030	2005	*
Metabolism	CAMP factor homologues in Propionibacterium acnes: a new protein family differentially expressed by types I and II.	Valanne S, McDowell A, Ramage G, Tunney MM, Einarsson GG, O'Hagan S, Wisdom GB, Fairley D, Bhatia A, Maisonneuve JF, Lodes M, Persing DH, Patrick S	Microbiology (Reading)	10.1099/mic.0.27788-0	2005	*
Metabolism	Hydrogel patches containing triclosan for acne treatment.	Lee TW, Kim JC, Hwang SJ	Eur J Pharm Biopharm	10.1016/s0939-6411(03)00137-1	2003	*
Enzymology	In vitro and in vivo antibacterial activity of T-3912, a novel non-fluorinated topical quinolone.	Yamakawa T, Mitsuyama J, Hayashi K	J Antimicrob Chemother	10.1093/jac/49.3.455	2002	*
Metabolism	Biotyping of Propionibacterium acnes isolated from normal human facial skin.	Kishishita M, Ushijima T, Ozaki Y, Ito Y	Appl Environ Microbiol	10.1128/aem.38.4.585-589.1979	1979	*
	Efficacy of Three Povidone Iodine Formulations against Cutibacterium acnes Assessed through In Vitro Studies: A Preliminary Study.	Pichon M, Burucoa C, Evplanov V, Favalli F	Antibiotics (Basel)	10.3390/antibiotics11050665	2022	*
	Effectiveness of topical adjuvants in reducing biofilm formation on orthopedic implants: an in vitro analysis.	Kia C, Cusano A, Messina J, Muench LN, Chadayammuri V, McCarthy MB, Umejiego E, Mazzocca AD	J Shoulder Elbow Surg	10.1016/j.jse.2020.12.009	2021	*
	Exploring the Anti-Acne Potential of Impepho [Helichrysum odoratissimum (L.) Sweet] to Combat Cutibacterium acnes Virulence.	De Canha MN, Komarnytsky S, Langhansova L, Lall N	Front Pharmacol	10.3389/fphar.2019.01559	2020	*

References

#919	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 1897

#20215

Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )

#20218

Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )

#24963

C. F. P. K. Scholz, Mogens: The natural history of cutaneous propionibacteria, and reclassification of selected species within the genus Propionibacterium to the proposed novel genera Acidipropionibacterium gen. nov., Cutibacterium gen. nov. and Pseudopropionibacterium gen. nov.. IJSEM 66: 4422 - 4432 2016 ( DOI 10.1099/ijsem.0.001367 , PubMed 27488827 )

#42199 ; Curators of the CIP;
#44423 Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 1794

#66792

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#67770 Japan Collection of Microorganism (JCM) ; Curators of the JCM;

#68380

Automatically annotated from API rID32A .

#68382

Automatically annotated from API zym .

#69479

João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .

#69480

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#69481

Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch: Predictions based on the model GenomeNet Sporulation v. 1 . ( DOI 10.21203/rs.3.rs-2527258/v1 )

#81849

Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.: StrainInfo: A central database for resolving microbial strain identifiers . ( DOI 10.60712/SI-ID389260.1 )

#116031 Collection of Institut Pasteur ; Curators of the CIP; CIP 53.117
* These data were automatically processed and therefore are not curated

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