Acidipropionibacterium acidipropionici (DSM 4900, ATCC 25562, VPI 0399)

Name: Acidipropionibacterium acidipropionici (DSM 4900, ATCC 25562, VPI 0399)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 12633

Type strain

Strain Designation 14X, 0179

Culture col. no. DSM 4900 ATCC 25562 VPI 0399 14X NCIMB 11858 2 more

NCBI tax ID(s) 1111734 1748

Special Collections DSMZ CIP

History <- ATCC <- W.E.C. Moore, VPI 0399 <- A. Prévot, 14X (Propionibacterium pentosaceum) CIP <- 1987, NCIB <- ATCC <- W.E.C. Moore, Virginia Polytechnic Inst., Blacksburg, USA: strain 0179 <- 1924, A. Prévot, Inst. Pasteur, Paris, France: strain 14X <- Orla-Jensen, Propionibacterium pentosaceum

Links

Acidipropionibacterium acidipropionici 14X is an anaerobe, mesophilic, Gram-positive prokaryote that was isolated from Environment, soil.

Gram-positive rod-shaped anaerobe mesophilic genome sequence 16S sequence

Name and taxonomic classification

SI-ID 311069

ATCC 25562,CIP 103025,NCIB 11858,DSM 4900,NCIMB 11858,KCTC 5020,CGMCC 1.2230

@ref 20215

Last LPSN update 2025-12-16 09:49:54

Domain Bacillati

Phylum Actinomycetota

Class Actinomycetes

Order Propionibacteriales

Family Propionibacteriaceae

Genus Acidipropionibacterium

Species Acidipropionibacterium acidipropionici

Full scientific name Acidipropionibacterium acidipropionici (Orla-Jensen 1909) Scholz and Kilian 2016

Synonyms (1)

Propionibacterium acidipropionici

BacDive ID	Other strains from **Acidipropionibacterium acidipropionici** (5)	Type strain
12634	A. acidipropionici 4, DSM 20272, ATCC 4875, NCDO 570, NCIB 8070, ...
12635	A. acidipropionici 61, P-21, DSM 20273, ATCC 4965, NCDO 563, ...
149200	A. acidipropionici CCUG 37258
162836	A. acidipropionici JCM 20264, IAM 1714
165403	A. acidipropionici JCM 6431

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Confidence
116013	positive	rod-shaped
125438			93
125438	positive		90.231
125439	positive		99.1

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
1867	PYG MEDIUM (MODIFIED) (DSMZ Medium 104)	Medium recipe at MediaDive	Name: PYG MEDIUM (modified) (DSMZ Medium 104) Composition: Yeast extract 10.0 g/l Peptone 5.0 g/l Trypticase peptone 5.0 g/l Beef extract 5.0 g/l Glucose 5.0 g/l L-Cysteine HCl x H2O 0.5 g/l NaHCO3 0.4 g/l NaCl 0.08 g/l K2HPO4 0.04 g/l KH2PO4 0.04 g/l MgSO4 x 7 H2O 0.02 g/l CaCl2 x 2 H2O 0.01 g/l Hemin 0.005 g/l Ethanol 0.0038 g/l Resazurin 0.001 g/l Tween 80 Vitamin K1 NaOH Distilled water
42205	MEDIUM 20 - for Anaerobic bacteria		Agar (15.000 g);Glucose (5.000 g);Yeast extract (20.000 g);Tryptone (30.000 g);Cysteine hydrochloride (0.500 g);distilled water (1000.000 ml);Hemin solution -M00149 (25.000 ml)
116013	CIP Medium 20	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)	Range
1867	positive	growth	37	mesophilic
42205	positive	growth	30	mesophilic

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance
1867	anaerobe
116013	facultative anaerobe

Murein

@ref	Murein short key	Type
1867	A41.01	A3gamma LL-Dpm-Gly

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68380	29016 ChEBI	arginine	-	hydrolysis	from API rID32A
68371	17108 ChEBI	D-arabinose	+	builds acid from	from API 50CH acid
68371	18333 ChEBI	D-arabitol	+	builds acid from	from API 50CH acid
68371	15824 ChEBI	D-fructose	+	builds acid from	from API 50CH acid
68371	28847 ChEBI	D-fucose	-	builds acid from	from API 50CH acid
68371	12936 ChEBI	D-galactose	+	builds acid from	from API 50CH acid
68371	17634 ChEBI	D-glucose	+	builds acid from	from API 50CH acid
68371	62318 ChEBI	D-lyxose	-	builds acid from	from API 50CH acid
68371	16899 ChEBI	D-mannitol	+	builds acid from	from API 50CH acid
68380	16024 ChEBI	D-mannose	+	fermentation	from API rID32A
68371	16024 ChEBI	D-mannose	+	builds acid from	from API 50CH acid
68371	16988 ChEBI	D-ribose	+	builds acid from	from API 50CH acid
68371	17924 ChEBI	D-sorbitol	+	builds acid from	from API 50CH acid
68371	16443 ChEBI	D-tagatose	-	builds acid from	from API 50CH acid
68371	65327 ChEBI	D-xylose	-	builds acid from	from API 50CH acid
68371	17113 ChEBI	erythritol	+	builds acid from	from API 50CH acid
68371	4853 ChEBI	esculin	+	builds acid from	from API 50CH acid
68371	16813 ChEBI	galactitol	-	builds acid from	from API 50CH acid
68371	28066 ChEBI	gentiobiose	-	builds acid from	from API 50CH acid
68371	24265 ChEBI	gluconate	+	builds acid from	from API 50CH acid
68371	17754 ChEBI	glycerol	+	builds acid from	from API 50CH acid
68371	28087 ChEBI	glycogen	-	builds acid from	from API 50CH acid
68371	15443 ChEBI	inulin	-	builds acid from	from API 50CH acid
68371	30849 ChEBI	L-arabinose	+	builds acid from	from API 50CH acid
68371	18403 ChEBI	L-arabitol	+	builds acid from	from API 50CH acid
68371	18287 ChEBI	L-fucose	-	builds acid from	from API 50CH acid
68380	29985 ChEBI	L-glutamate	-	degradation	from API rID32A
68371	17266 ChEBI	L-sorbose	-	builds acid from	from API 50CH acid
68371	65328 ChEBI	L-xylose	-	builds acid from	from API 50CH acid
68371	17716 ChEBI	lactose	+	builds acid from	from API 50CH acid
68371	17306 ChEBI	maltose	+	builds acid from	from API 50CH acid
68371	6731 ChEBI	melezitose	+	builds acid from	from API 50CH acid
68371	28053 ChEBI	melibiose	-	builds acid from	from API 50CH acid
68371	43943 ChEBI	methyl alpha-D-mannoside	-	builds acid from	from API 50CH acid
68371	74863 ChEBI	methyl beta-D-xylopyranoside	-	builds acid from	from API 50CH acid
68371	17268 ChEBI	myo-inositol	+	builds acid from	from API 50CH acid
68380	17632 ChEBI	nitrate	-	reduction	from API rID32A
116013	17632 ChEBI	nitrate	+	reduction
116013	16301 ChEBI	nitrite	-	reduction
68371		Potassium 2-ketogluconate	-	builds acid from	from API 50CH acid
68371		Potassium 5-ketogluconate	-	builds acid from	from API 50CH acid
68371	16634 ChEBI	raffinose	-	builds acid from	from API 50CH acid
68380	16634 ChEBI	raffinose	+	fermentation	from API rID32A
68371	15963 ChEBI	ribitol	+	builds acid from	from API 50CH acid
68371	17992 ChEBI	sucrose	+	builds acid from	from API 50CH acid
68371	27082 ChEBI	trehalose	+	builds acid from	from API 50CH acid
68380	27897 ChEBI	tryptophan	-	energy source	from API rID32A
68371	32528 ChEBI	turanose	+	builds acid from	from API 50CH acid
68380	16199 ChEBI	urea	-	hydrolysis	from API rID32A
68371	17151 ChEBI	xylitol	+	builds acid from	from API 50CH acid

Metabolite production

@ref	Chebi-ID	Metabolite	Production
68380	35581 ChEBI	indole		from API rID32A
116013	35581 ChEBI	indole

Metabolite tests

@ref	Chebi-ID	Metabolite	Indole test
68380	35581 ChEBI	indole	-	from API rID32A

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
68382	alkaline phosphatase	+	3.1.3.1	from API zym
68380	alkaline phosphatase	+	3.1.3.1	from API rID32A
68380	alpha-arabinosidase	+	3.2.1.55	from API rID32A
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	+	3.2.1.22	from API zym
68382	alpha-glucosidase	+	3.2.1.20	from API zym
68380	alpha-glucosidase	+	3.2.1.20	from API rID32A
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68380	arginine dihydrolase	-	3.5.3.6	from API rID32A
68382	beta-galactosidase	+	3.2.1.23	from API zym
68380	beta-galactosidase	+	3.2.1.23	from API rID32A
68380	beta-Galactosidase 6-phosphate	-		from API rID32A
68382	beta-glucosidase	+	3.2.1.21	from API zym
68382	beta-glucuronidase	-	3.2.1.31	from API zym
68380	beta-glucuronidase	-	3.2.1.31	from API rID32A
116013	catalase	-	1.11.1.6
68382	cystine arylamidase	-	3.4.11.3	from API zym
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	-		from API zym
68380	glutamate decarboxylase	-	4.1.1.15	from API rID32A
68380	glutamyl-glutamate arylamidase	-		from API rID32A
68382	leucine arylamidase	+	3.4.11.1	from API zym
68380	leucyl glycin arylamidase	-	3.4.11.1	from API rID32A
68382	lipase (C 14)	-		from API zym
68382	N-acetyl-beta-glucosaminidase	+	3.2.1.52	from API zym
68380	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API rID32A
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
116013	oxidase	-
68380	proline-arylamidase	+	3.4.11.5	from API rID32A
68380	pyrrolidonyl arylamidase	-	3.4.19.3	from API rID32A
68382	trypsin	-	3.4.21.4	from API zym
68380	tryptophan deaminase	-	4.1.99.1	from API rID32A
116013	urease	-	3.5.1.5
68380	urease	-	3.5.1.5	from API rID32A
68382	valine arylamidase	-		from API zym

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
116013	-	+	+	-	-	+	-	-	-	-	+	+	+	+	-	+	+	+	-	-

API 50CHac

@ref	ControlQ	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
116013	not determinedn.d.	+	+	+	+	+	-	-	+	-	+	+	+	+	-	+/-	-	+	+	+	-	+/-	+/-	+/-	+/-	+	+/-	+/-	+	+	-	+	+	-	+	-	+/-	-	+	-	+	-	-	-	-	+	+	+	-	-

API rID32A

@ref	URE	ADH (Arg)	alpha GAL	beta GAL	beta-Galactosidase 6-phosphatebeta GP	alpha GLU	beta GLU	alpha ARA	beta GUR	beta-N-Acetyl-beta-glucosaminidasebeta NAG	MNE	RAF	GDC	alpha FUC	Reduction of nitrateNIT	IND	PAL	L-arginine arylamidaseArgA	ProA	LGA	Phenylalanine arylamidasePheA	Leucine arylamidaseLeuA	PyrA	Tyrosine arylamidaseTyrA	Alanine arylamidaseAlaA	Glycin arylamidaseGlyA	Histidine arylamidaseHisA	Glutamyl-glutamate arylamidaseGGA	Serine arylamidaseSerA
1867	-	-	+/-	+	-	+	+/-	+	-	-	+	+	-	-	-	-	+	+	+	-	-	+/-	-	-	+/-	+/-	-	-	-
1867	-	-	+/-	+	-	+	+/-	+	-	-	+	+	-	-	-	-	+	+/-	+	-	-	+/-	-	+/-	+/-	+/-	+/-	-	+/-
1867	-	-	+	+	-	+	+	+	-	-	+	+	-	+/-	-	-	+	+	+	-	-	+/-	-	+/-	+	+	-	-	-
1867	-	-	+	+	-	+	+	+	-	-	+	+	-	+	-	-	+	+	+	not determinedn.d.	+/-	+/-	-	+/-	+/-	+/-	+/-	-	+/-

Isolation, sampling and environmental information

Isolation

@ref	Sample type	Country	Country ISO 3 Code	Continent
116013	Environment, soil	United States of America	USA	North America

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
1867	1	Risk group (German classification) According to TRBA 466
116013	1	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM42784v1 assembly for Acidipropionibacterium acidipropionici DSM 4900	scaffold	GCA_000427845	1111734.3	2513237117	1111734	67.54

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
20218	Propionibacterium acidipropionici strain CIP 103025 16S ribosomal RNA gene, partial sequence	AY883042	459		1748

GC content

1867

GC-content (mol%)66.0

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Acidipropionibacterium acidipropionici DSM 4900
NCBI: GCA_000427845

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	no	73.80	no
125439	motility	BacteriaNetⓘ	no	80.10	no
125439	gram_stain	BacteriaNetⓘ	positive	99.10	no
125439	oxygen_tolerance	BacteriaNetⓘ	facultative anaerobe	83.30	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Acidipropionibacterium acidipropionici DSM 4900 DSM 4900
NCBI: GCA_000427845.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	90.23	no
125438	anaerobic	anaerobicⓘ	no	75.59	no
125438	aerobic	aerobicⓘ	no	62.13	yes
125438	spore-forming	spore-formingⓘ	no	72.55	no
125438	thermophilic	thermophileⓘ	no	95.13	yes
125438	flagellated	motile2+ⓘ	no	93.00	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	High cell density sequential batch fermentation for enhanced propionic acid production from glucose and glycerol/glucose mixture using Acidipropionibacterium acidipropionici.	Dishisha T, Jain M, Hatti-Kaul R.	Microb Cell Fact	10.1186/s12934-024-02366-5	2024
	Membrane-based continuous fermentation with cell recycling for propionic acid production from glycerol by Acidipropionibacterium acidipropionici.	Cavero-Olguin VH, Dishisha T, Hatti-Kaul R.	Microb Cell Fact	10.1186/s12934-023-02049-7	2023
Biotechnology	An artificial coculture fermentation system for industrial propanol production.	Hocq R, Sauer M.	FEMS Microbes	10.1093/femsmc/xtac013	2022
	The Antimicrobial Effect of Various Single-Strain and Multi-Strain Probiotics, Dietary Supplements or Other Beneficial Microbes against Common Clinical Wound Pathogens.	Fijan S, Kocbek P, Steyer A, Vodicar PM, Strauss M.	Microorganisms	10.3390/microorganisms10122518	2022
	One-Year Monitoring of Prevalence and Diversity of Dairy Propionic Acid Bacteria in Raw Milk by Means of Culture-Dependent and Culture-Independent Methods	Bucher C, Burtscher J, Zitz U, Domig K.	Foods		2024
Genetics	Red-Brown Pigmentation of Acidipropionibacterium jensenii Is Tied to Haemolytic Activity and cyl-Like Gene Cluster.	Deptula P, Loivamaa I, Smolander OP, Laine P, Roberts RJ, Piironen V, Paulin L, Savijoki K, Auvinen P, Varmanen P.	Microorganisms	10.3390/microorganisms7110512	2019
Metabolism	Batch- and continuous propionic acid production from glycerol using free and immobilized cells of Propionibacterium acidipropionici.	Dishisha T, Alvarez MT, Hatti-Kaul R	Bioresour Technol	10.1016/j.biortech.2012.05.079	2012

References

#1867	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 4900
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#42205	; Curators of the CIP;
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#68371	Automatically annotated from API 50CH acid .
#68380	Automatically annotated from API rID32A .
#68382	Automatically annotated from API zym .
#116013	Collection of Institut Pasteur ; Curators of the CIP; CIP 103025
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Acidipropionibacterium acidipropionici (DSM 4900, ATCC 25562, VPI 0399)

Name and taxonomic classification

Morphology

Cell morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Murein

Metabolite utilization

Metabolite production

Metabolite tests

Enzymes

API zym

API 50CHac

API rID32A

Isolation, sampling and environmental information

Isolation

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_000427845

16S sequences

GC content

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

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