Prevotella oralis (CCUG 15408, JCM 12251, DSM 20702)

Name: Prevotella oralis (CCUG 15408, JCM 12251, DSM 20702)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 12532

Type strain

Culture col. no. CCUG 15408 JCM 12251 DSM 20702 ATCC 33269 NCTC 11459 1 more

NCBI tax ID(s) 873533 28134

Special Collections DSMZ CCUG JCM

History DSMZ <- NCTC <- L.V. Holdeman (VPI D27B-24) JCM <-- CCUG 15408 <-- ATCC 33269 <-- L. V. Holdeman VPI D27B-24.

Links

Prevotella oralis CCUG 15408 is an anaerobe human pathogen that was isolated from human peridontal pocket.

anaerobe human pathogen genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 40420

ATCC 33269,NCTC 11459,CCUG 15408,DSM 20702,JCM 12251

@ref 20215

Last LPSN update 2026-05-29 08:27:49

Domain Bacteria

Phylum Bacteroidota

Class Bacteroidia

Order Bacteroidales

Family Prevotellaceae

Genus Prevotella

Species Prevotella oralis

Full scientific name Prevotella oralis (Loesche et al. 1964) Shah and Collins 1990

Synonyms (2)

Bacteroides oralis
Hoylesella oralis

BacDive ID	Other strains from **Prevotella oralis** (2)	Type strain
156880	P. oralis CCUG 66283
156905	P. oralis CCUG 66588

Morphology

Cell morphology

@ref	Confidence	Gram stain
125438	90
125438	93.29	negative
125439	95.171	negative

Culture and growth conditions

Culture medium

@ref	Name	Growth	Medium link	Composition
8780	CHOPPED MEAT MEDIUM WITH CARBOHYDRATES (DSMZ Medium 110)		Medium recipe at MediaDive	Name: CHOPPED MEAT MEDIUM WITH CARBOHYDRATES (DSMZ Medium 110) Composition: Ground beef 500.0 g/l Casitone 30.0 g/l Agar 15.0 g/l K2HPO4 5.0 g/l Yeast extract 5.0 g/l D-Glucose 4.0 g/l Starch 1.0 g/l Maltose 1.0 g/l Cellobiose 1.0 g/l L-Cysteine HCl 0.5 g/l Ethanol 0.19 g/l Vitamin K3 0.05 g/l Hemin 0.005 g/l Sodium resazurin 0.0005 g/l Vitamin K1 NaOH Distilled water
8780	COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)		Medium recipe at MediaDive	Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base

Culture temp

@ref	Growth	Type	Temperature (°C)
8780	positive	growth	37
46247	positive	growth	37
67770	positive	growth	37

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
8780	anaerobe
46247	anaerobe
125438	anaerobe	92.703
125439	facultative anaerobe	90.809

Spore formation

@ref	Spore formation	Confidence
125439		99.968
125438		91.092

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68380	29016 ChEBI	arginine	-	hydrolysis	from API rID32A
68380	29985 ChEBI	L-glutamate	-	degradation	from API rID32A
68380	17632 ChEBI	nitrate	-	reduction	from API rID32A
68380	27897 ChEBI	tryptophan	-	energy source	from API rID32A
68380	16199 ChEBI	urea	-	hydrolysis	from API rID32A

Metabolite production

@ref	Chebi-ID	Metabolite	Production
68380	35581 ChEBI	indole		from API rID32A

Metabolite tests

@ref	Chebi-ID	Metabolite	Indole test
68380	35581 ChEBI	indole	-	from API rID32A

Enzymes

@ref	Value	Activity	Ec
68380	alanine arylamidase	+	3.4.11.2	from API rID32A
68380	alkaline phosphatase	+	3.1.3.1	from API rID32A
68380	alpha-arabinosidase	-	3.2.1.55	from API rID32A
68380	alpha-galactosidase	+	3.2.1.22	from API rID32A
68380	alpha-glucosidase	+	3.2.1.20	from API rID32A
68380	arginine dihydrolase	-	3.5.3.6	from API rID32A
68380	beta-galactosidase	+	3.2.1.23	from API rID32A
68380	beta-Galactosidase 6-phosphate	-		from API rID32A
68380	beta-glucuronidase	-	3.2.1.31	from API rID32A
68380	glutamate decarboxylase	-	4.1.1.15	from API rID32A
68380	glycin arylamidase	-		from API rID32A
68380	histidine arylamidase	-		from API rID32A
68380	L-arginine arylamidase	-		from API rID32A
68380	leucine arylamidase	-	3.4.11.1	from API rID32A
68380	leucyl glycin arylamidase	+	3.4.11.1	from API rID32A
68380	N-acetyl-beta-glucosaminidase	+	3.2.1.52	from API rID32A
68380	phenylalanine arylamidase	-		from API rID32A
68380	proline-arylamidase	-	3.4.11.5	from API rID32A
68380	pyrrolidonyl arylamidase	-	3.4.19.3	from API rID32A
68380	serine arylamidase	-		from API rID32A
68380	tryptophan deaminase	-	4.1.99.1	from API rID32A
68380	tyrosine arylamidase	-		from API rID32A
68380	urease	-	3.5.1.5	from API rID32A

Pathway annotation

Computationally determined by

@ref	pathway	enzyme coverage	annotated reactions
66794	C4 and CAM-carbon fixation	100	8 of 8
66794	cis-vaccenate biosynthesis	100	2 of 2
66794	CDP-diacylglycerol biosynthesis	100	2 of 2
66794	suberin monomers biosynthesis	100	2 of 2
66794	glycogen metabolism	100	5 of 5
66794	folate polyglutamylation	100	1 of 1
66794	anapleurotic synthesis of oxalacetate	100	1 of 1
66794	ppGpp biosynthesis	100	4 of 4
66794	vitamin K metabolism	100	5 of 5
66794	palmitate biosynthesis	90.91	20 of 22
66794	starch degradation	90	9 of 10
66794	chorismate metabolism	88.89	8 of 9
66794	lipid A biosynthesis	88.89	8 of 9
66794	d-mannose degradation	88.89	8 of 9
66794	gluconeogenesis	87.5	7 of 8
66794	NAD metabolism	83.33	15 of 18
66794	vitamin B6 metabolism	81.82	9 of 11
66794	flavin biosynthesis	80	12 of 15
66794	peptidoglycan biosynthesis	80	12 of 15
66794	photosynthesis	78.57	11 of 14
66794	tetrahydrofolate metabolism	78.57	11 of 14
66794	aspartate and asparagine metabolism	77.78	7 of 9
66794	valine metabolism	77.78	7 of 9
66794	CMP-KDO biosynthesis	75	3 of 4
66794	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	75	6 of 8
66794	sulfopterin metabolism	75	3 of 4
66794	isoleucine metabolism	75	6 of 8
66794	glycogen biosynthesis	75	3 of 4
66794	acetate fermentation	75	3 of 4
66794	cardiolipin biosynthesis	71.43	5 of 7
66794	glycolysis	70.59	12 of 17
66794	purine metabolism	70.21	66 of 94
66794	threonine metabolism	70	7 of 10
66794	pyrimidine metabolism	68.89	31 of 45
66794	serine metabolism	66.67	6 of 9
66794	acetoin degradation	66.67	2 of 3
66794	dTDPLrhamnose biosynthesis	62.5	5 of 8
66794	vitamin B1 metabolism	61.54	8 of 13
66794	O-antigen biosynthesis	60	3 of 5
66794	lipoate biosynthesis	60	3 of 5
66794	hydrogen production	60	3 of 5
66794	phenylacetate degradation (aerobic)	60	3 of 5
66794	cellulose degradation	60	3 of 5
66794	CO2 fixation in Crenarchaeota	55.56	5 of 9
66794	d-xylose degradation	54.55	6 of 11
66794	phenylalanine metabolism	53.85	7 of 13
66794	isoprenoid biosynthesis	53.85	14 of 26
66794	glutamate and glutamine metabolism	53.57	15 of 28
66794	ketogluconate metabolism	50	4 of 8
66794	degradation of hexoses	50	9 of 18
66794	adipate degradation	50	1 of 2
66794	cysteine metabolism	50	9 of 18
66794	Entner Doudoroff pathway	50	5 of 10
66794	kanosamine biosynthesis II	50	1 of 2
66794	glycolate and glyoxylate degradation	50	3 of 6
66794	phenylmercury acetate degradation	50	1 of 2
66794	lactate fermentation	50	2 of 4
66794	butanoate fermentation	50	2 of 4
66794	ethanol fermentation	50	1 of 2
66794	coenzyme A metabolism	50	2 of 4
66794	histidine metabolism	48.28	14 of 29
66794	alanine metabolism	48.28	14 of 29
66794	methionine metabolism	46.15	12 of 26
66794	leucine metabolism	46.15	6 of 13
66794	metabolism of disaccharids	45.45	5 of 11
66794	lipid metabolism	45.16	14 of 31
66794	oxidative phosphorylation	43.96	40 of 91
66794	polyamine pathway	43.48	10 of 23
66794	reductive acetyl coenzyme A pathway	42.86	3 of 7
66794	lysine metabolism	42.86	18 of 42
66794	tryptophan metabolism	42.11	16 of 38
66794	degradation of aromatic, nitrogen containing compounds	41.67	5 of 12
66794	arginine metabolism	41.67	10 of 24
66794	methylglyoxal degradation	40	2 of 5
66794	factor 420 biosynthesis	40	2 of 5
66794	metabolism of amino sugars and derivatives	40	2 of 5
66794	propionate fermentation	40	4 of 10
66794	degradation of sugar acids	40	10 of 25
66794	coenzyme M biosynthesis	40	4 of 10
66794	arachidonate biosynthesis	40	2 of 5
66794	phosphatidylethanolamine bioynthesis	38.46	5 of 13
66794	non-pathway related	36.84	14 of 38
66794	pentose phosphate pathway	36.36	4 of 11
66794	citric acid cycle	35.71	5 of 14
66794	tyrosine metabolism	35.71	5 of 14
66794	vitamin B12 metabolism	35.29	12 of 34
66794	UDP-GlcNAc biosynthesis	33.33	1 of 3
66794	formaldehyde oxidation	33.33	1 of 3
66794	acetyl CoA biosynthesis	33.33	1 of 3
66794	L-lactaldehyde degradation	33.33	1 of 3
66794	octane oxidation	33.33	1 of 3
66794	IAA biosynthesis	33.33	1 of 3
66794	enterobactin biosynthesis	33.33	1 of 3
66794	selenocysteine biosynthesis	33.33	2 of 6
66794	sulfate reduction	30.77	4 of 13
66794	urea cycle	30.77	4 of 13
66794	glycine metabolism	30	3 of 10
66794	myo-inositol biosynthesis	30	3 of 10
66794	ubiquinone biosynthesis	28.57	2 of 7
66794	cyclohexanol degradation	25	1 of 4
66794	biotin biosynthesis	25	1 of 4
66794	degradation of sugar alcohols	25	4 of 16
66794	toluene degradation	25	1 of 4
66794	glutathione metabolism	21.43	3 of 14

API rID32A

@ref	URE	ADH (Arg)	alpha GAL	beta GAL	beta-Galactosidase 6-phosphatebeta GP	alpha GLU	beta GLU	alpha ARA	beta GUR	beta-N-Acetyl-beta-glucosaminidasebeta NAG	MNE	RAF	GDC	alpha FUC	Reduction of nitrateNIT	IND	PAL	L-arginine arylamidaseArgA	ProA	LGA	Phenylalanine arylamidasePheA	Leucine arylamidaseLeuA	PyrA	Tyrosine arylamidaseTyrA	Alanine arylamidaseAlaA	Glycin arylamidaseGlyA	Histidine arylamidaseHisA	Glutamyl-glutamate arylamidaseGGA	Serine arylamidaseSerA
8780	-	-	+	+	-	+	+/-	-	-	+	-	-	-	-	-	-	+	-	-	+	-	-	-	-	+	-	-	+/-	-
8780	-	-	+	+	-	+	+	-	-	+	+	+	-	+	-	-	+	-	-	+	-	-	-	-	+	-	-	-	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Host	#Human	-
#Host Body-Site	#Oral cavity and airways	#Periodontal pocket

Isolation

@ref	Sample type	Host species
8780	human peridontal pocket	Homo sapiens
46247	Human periodontal pocket	Homo sapiens
67770	Human oral cavity	Homo sapiens

Taxonmaps

69479

Global distribution of 16S sequence AY323522 (>99% sequence identity) for Prevotella oralis subclade from Microbeatlas

Aquatic Samples	256
Soil Samples	214
Animal Samples	22578
Plant Samples	117
Total Samples	23165

Interaction and safety

Risk assessment

@ref	Pathogenicity human	Pathogenicity animal	Biosafety level	Biosafety level comment
8780			2	Risk group (German classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
67770	ASM18514v2 assembly for Hoylesella oralis ATCC 33269	scaffold	GCA_000185145	873533.3	649989988	873533	78.04
67770	IMG-taxon 2695421016 annotated assembly for Hoylesella oralis DSM 20702	contig	GCA_900129435	28134.3	2695421016	28134	76.08

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Prevotella oralis 16S ribosomal RNA gene, partial sequence	AY323522	1510	873533
20218	Prevotella oralis gene for 16S ribosomal RNA, partial sequence, strain: JCM 12251	AB547698	1496	873533
8780	Prevotella oralis ATCC 33269) 16S ribosomal RNA gene, complete sequence	L16480	1481	28134

GC content

@ref	GC-content (mol%)	Method
8780	43.1
8780	44.5	sequence analysis
67770	45	thermal denaturation, midpoint method (Tm)

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: ASM18514v2 assembly for Hoylesella oralis ATCC 33269
NCBI: GCA_000185145

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	facultative anaerobe	90.81	no
125439	motility	BacteriaNetⓘ	no	79.97	no
125439	gram_stain	BacteriaNetⓘ	negative	95.17	no
125439	spore_formation	BacteriaNetⓘ	no	99.97	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Prevotella oralis ATCC 33269
PATRIC: 873533.3

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	no	93.29	no
125438	anaerobic	anaerobicⓘ	yes	92.70	yes
125438	aerobic	aerobicⓘ	no	95.29	yes
125438	spore-forming	spore-formingⓘ	no	91.09	no
125438	thermophilic	thermophileⓘ	no	95.88	no
125438	flagellated	motile2+ⓘ	no	90.00	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	Changes in Gut Microbiota According to Disease Severity in a Lupus Mouse Model.	Han EJ, Ahn JS, Choi YJ, Kim DH, Chung HJ.	Int J Mol Sci	10.3390/ijms26031006	2025
Pathogenicity	An electron microscope survey of the surface structures and hydrophobicity of oral and non-oral species of the bacterial genus Bacteroides.	Handley PS, Tipler LS	Arch Oral Biol	10.1016/0003-9969(86)90047-6	1986

References

#8780	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 20702
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#46247	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 15408
#66794	Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg: BRENDA, the ELIXIR core data resource in 2021: new developments and updates. Nucleic Acids Res. 49: D498 - D508 2020 ( DOI 10.1093/nar/gkaa1025 , PubMed 33211880 )
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68380	Automatically annotated from API rID32A .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Prevotella oralis (CCUG 15408, JCM 12251, DSM 20702)

Name and taxonomic classification

Morphology

Cell morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Spore formation

Metabolite utilization

Metabolite production

Metabolite tests

Enzymes

Pathway annotation

API rID32A

Isolation, sampling and environmental information

Isolation source categories

Isolation

Taxonmaps

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_000185145

16S sequences

GC content

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

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