Name: Prevotella intermedia B422
Creator: BacDive
License: http://creativecommons.org/licenses/by-nc/4.0/

Strain identifier

BacDive ID: 12531

Type strain:

Species: Prevotella intermedia

Strain Designation: B422

Culture col. no.: DSM 20706, ATCC 25611, KCTC 15693, CCUG 24041, JCM 7365, JCM 12248, VPI 4197, JCM 11150, BCRC 14416, CIP 103682, NCTC 13070, CIP 101222, KCTC 3692

Strain history: <- DSM <- ATCC <- LV Holdeman, VPI 4197 <- S Finegold, B422

NCBI tax ID(s): 1122984 (strain), 28131 (species)

SI-ID 38613

ATCC 25611, JCM 7365, CCUG 24041, DSM 20706, CIP 103682, CCRC 14416, KCTC 3692, BCRC 14416, BCRC 14477, CCRC 14477, JCM 12248, JCM 11150, CIP 101222, NCTC 13070

Other strains from Prevotella intermedia

P. intermedia CCUG 25283
P. intermedia CCUG 25287
P. intermedia CCUG 25289
P. intermedia CCUG 25672
P. intermedia CCUG 25673
P. intermedia CCUG 25676
P. intermedia CCUG 27725
P. intermedia CCUG 27726
P. intermedia CCUG 27727
P. intermedia CCUG 31410
P. intermedia CCUG 36776

Section

Prevotella intermedia B422 is an anaerobe, mesophilic, rod-shaped human pathogen that was isolated from empyema.

rod-shaped
anaerobe
human pathogen
mesophilic
16S sequence
Bacteria
genome sequence

Information on the name and the taxonomic classification. Name and taxonomic classification

	Last LPSN update	14-12-2023 (DD-MM-YYYY)
	Domain	"Bacteria"
	Phylum	*Bacteroidota*
	Class	*Bacteroidia*
	Order	*Bacteroidales*
	Family	*Prevotellaceae*
	Genus	*Prevotella*
	Species	**Prevotella intermedia**
	Full Scientific Name (LPSN)	Prevotella intermedia (Holdeman and Moore 1970) Shah and Collins 1990

	Synonym	Bacteroides melaninogenicus subsp. intermedius
	Synonym	Bacteroides intermedius

Information on morphological and physiological properties Morphology

[Ref.: #67771]	Gram stain	negative
[Ref.: #69480]	Gram stain	negative Confidence in %99.998

[Ref.: #67771]	Cell shape	rod-shaped

[Ref.: #8783]

Incubation period

1-2 days

Information on culture and growth conditions Culture and growth conditions

[Ref.: #8783]

Culture medium

COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)

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Culture medium growth

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Culture medium link

Medium recipe at MediaDive

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Culture medium composition

expand / minimize

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Culture medium

PYG MEDIUM (MODIFIED) (DSMZ Medium 104)

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Culture medium growth

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Culture medium link

Medium recipe at MediaDive

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Culture medium composition

expand / minimize

		Temperature
[Ref.: #8783]	growth	37 °C
[Ref.: #67770]	growth	37 °C
[Ref.: #67771]	growth	37 °C

[Ref.: #8783]	Temperature range	mesophilic
[Ref.: #67770]	Temperature range	mesophilic
[Ref.: #67771]	Temperature range	mesophilic

Information on physiology and metabolism Physiology and metabolism

[Ref.: #8783]	Oxygen tolerance	anaerobe
[Ref.: #67771]	Oxygen tolerance	anaerobe
[Ref.: #69480]	Oxygen tolerance	anaerobe Confidence in %99.599

[Ref.: #69481]	Ability of spore formation	no Confidence in %100
[Ref.: #69480]	Ability of spore formation	no Confidence in %99.998

	Metabolite	Utilization activity	Kind of utilization tested
[Ref.: #68380]	arginine ChEBI	-	hydrolysis	* from API rID32A
[Ref.: #68367]	cellobiose ChEBI	-	builds acid from	* from API 20A
[Ref.: #68367]	D-glucose ChEBI	+	builds acid from	* from API 20A
[Ref.: #68367]	D-mannose ChEBI	+	builds acid from	* from API 20A
[Ref.: #68367]	gelatin ChEBI	+	hydrolysis	* from API 20A
[Ref.: #68380]	L-glutamate ChEBI	-	degradation	* from API rID32A
[Ref.: #68367]	lactose ChEBI	-	builds acid from	* from API 20A
[Ref.: #68367]	maltose ChEBI	+	builds acid from	* from API 20A
[Ref.: #68380]	nitrate ChEBI	-	reduction	* from API rID32A
[Ref.: #68367]	raffinose ChEBI	+	builds acid from	* from API 20A
[Ref.: #68367]	sucrose ChEBI	+	builds acid from	* from API 20A
[Ref.: #68367]	tryptophan ChEBI	+	energy source	* from API 20A
[Ref.: #68367]	urea ChEBI	-	hydrolysis	* from API 20A, API rID32A
	Only first 10 entries are displayed. Click here to see all.

	Metabolite production	Metabolite	Production
[Ref.: #68367]		indole ChEBI	yes	* from API 20A

	Physiological tests	Metabolite	Indole test
[Ref.: #68367]		indole ChEBI	+	* from API 20A

	Enzyme	Enzyme activity	EC number
[Ref.: #68380]	alanine arylamidase	+	3.4.11.2	* from API rID32A
[Ref.: #68380]	alkaline phosphatase	+	3.1.3.1	* from API rID32A
[Ref.: #68380]	alpha-arabinosidase	-	3.2.1.55	* from API rID32A
[Ref.: #68380]	alpha-galactosidase	-	3.2.1.22	* from API rID32A
[Ref.: #68380]	arginine dihydrolase	-	3.5.3.6	* from API rID32A
[Ref.: #68380]	beta-galactosidase	-	3.2.1.23	* from API rID32A
[Ref.: #68380]	beta-Galactosidase 6-phosphate	-		* from API rID32A
[Ref.: #68380]	beta-glucosidase	-	3.2.1.21	* from API rID32A
[Ref.: #68380]	beta-glucuronidase	-	3.2.1.31	* from API rID32A
[Ref.: #68367]	catalase	-	1.11.1.6	* from API 20A
[Ref.: #68367]	gelatinase	+		* from API 20A
[Ref.: #68380]	glutamate decarboxylase	-	4.1.1.15	* from API rID32A
[Ref.: #68380]	glycin arylamidase	-		* from API rID32A
[Ref.: #68380]	leucine arylamidase	-	3.4.11.1	* from API rID32A
[Ref.: #68380]	leucyl glycin arylamidase	+	3.4.11.1	* from API rID32A
[Ref.: #68380]	N-acetyl-beta-glucosaminidase	-	3.2.1.52	* from API rID32A
[Ref.: #68380]	phenylalanine arylamidase	-		* from API rID32A
[Ref.: #68380]	pyrrolidonyl arylamidase	-	3.4.19.3	* from API rID32A
[Ref.: #68380]	tyrosine arylamidase	-		* from API rID32A
[Ref.: #68380]	urease	-	3.5.1.5	* from API rID32A, API 20A
	Only first 10 entries are displayed. Click here to see all.

Fatty acid profile

Metadata FA analysis

Reference

[Ref.: #47910]

Fatty acid	Percentage	ECL
C18:2 ω6,9c/C18:0 ANTE	32.6	17.724
C15:0 ANTEISO	17.9	14.711
C14:0 ISO	12.4	13.618
C15:0 ISO	10.7	14.621
C17:0 iso 3OH	8.5	18.161
C16:0	7.8	16
C18:0	3.2	18
C16:0 iso	2.5	15.626
C14:0	1.8	14
C13:0 iso	1.7	12.612
C17:0 iso	0.9	16.629

API® 20A:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	Indole productionIND	Urease/urea hydrolysisURE	Acid from D-glucoseGLU	Acid from D-mannitolMAN	Acid from lactoseLAC	Acid from sucroseSAC	Acid from maltoseMAL	Acid from salicinSAL	Acid from D-xyloseXYL	Acid from L-arabinoseARA	Gelatinase/gelatin hydrolysisGEL	Esculin hydrolysis/beta-glucosidaseESC	Acid from glycerolGLY	Acid from cellobioseCEL	Acid from D-mannoseMNE	Acid from melezitoseMLZ	Acid from raffinoseRAF	Acid from sorbitolSOR	Acid from L-rhamnoseRHA	Acid from trehaloseTRE	CatalaseCAT	Spores presentSPOR	GramGRAM	Morphology coccus="+" rod="-"COCC
[Ref.: #8783]	2049	+	-	+	+	-	+	+	+	+	+	+	+	+	-	+	+	+	+	+	+	-	not determinedn.d.	not determinedn.d.	not determinedn.d.
[Ref.: #8783]	2048	+	-	+	-	-	+	+	-	-	-	+	-	-	-	+	-	+	-	-	-	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.

API® rID32A:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	Urease/urea hydrolysisURE	Arginine dihydrolaseADH (Arg)	alpha-Galactosidasealpha GAL	beta-Galactosidasebeta GAL	beta-Galactosidase 6-phosphatebeta GP	alpha-Glucosidasealpha GLU	beta-Glucosidasebeta GLU	alpha-Arabinosidasealpha ARA	beta-Glucuronidasebeta GUR	beta-N-Acetyl-beta-glucosaminidasebeta NAG	Fermentation of D-mannoseMNE	Fermentation of raffinoseRAF	Glutamate decarboxylaseGDC	alpha-Fucosidasealpha FUC	Reduction of nitrateNIT	Indole productionIND	Alkaline phosphatasePAL	L-arginine arylamidaseArgA	Proline arylamidaseProA	Leucyl glycin arylamidaseLGA	Phenylalanine arylamidasePheA	Leucine arylamidaseLeuA	Pyrrolidonyl arylamidasePyrA	Tyrosine arylamidaseTyrA	Alanine arylamidaseAlaA	Glycin arylamidaseGlyA	Histidine arylamidaseHisA	Glutamyl-glutamate arylamidaseGGA	Serine arylamidaseSerA
[Ref.: #8783]	13288	-	-	-	-	-	+	-	-	-	-	-	-	-	+	-	+	+	+	+/-	+	-	-	-	-	+	-	+/-	+	-
[Ref.: #8783]	13035	-	-	-	-	-	+	-	-	-	-	+/-	+/-	-	+	-	+	+	+	-	+	-	-	-	-	+	-	-	+	-
[Ref.: #47910]	4394	-	-	-	-	-	+	-	-	-	-	-	-	-	+	-	-	+	+	-	+	-	-	-	-	+	-	+	+	-
[Ref.: #8783]	12351	-	-	-	-	-	+	-	-	-	-	-	+/-	-	+	-	+	+	+/-	-	+	-	-	-	-	+	-	-	+/-	-
[Ref.: #8783]	12350	-	-	-	-	-	+	-	-	-	-	-	+/-	-	-	-	+	+	-	-	+	-	-	-	-	+	-	-	+	-
[Ref.: #8783]	12349	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	+	+	-	+	-	-	-	-	+	-	-	-	-
[Ref.: #8783]	12348	-	-	-	-	-	+	-	-	-	-	-	+/-	-	-	-	+	+	+	-	+	-	-	-	-	+	-	-	+	-
[Ref.: #8783]	12347	-	-	-	-	-	+/-	-	-	-	-	-	-	-	-	-	-	+	+	-	+	-	-	-	-	+	-	-	+/-	+

Information on isolation source, the sampling and environmental conditions Isolation, sampling and environmental information

[Ref.: #8783]	Sample type/isolated from	empyema

[Ref.: #47910]	Sample type/isolated from	Empyema

[Ref.: #67770]	Sample type/isolated from	Empyema

[Ref.: #67771]	Sample type/isolated from	From empyema
* marker position based on {}

Isolation sources categories

#Host Body Product

#Fluids

What are isolation sources categories?

[Ref.: #69479]

Global distribution of 16S sequence X73965 (>99% sequence identity) for Prevotella intermedia subclade from Microbeatlas

Aquatic Samples	1863
Soil Samples	1452
Animal Samples	62951
Plant Samples	637
Total Samples	66903

Information on possible application of the strain and its possible interaction with e.g. potential hosts Safety information

[Ref.: #8783]	Pathogenicity (human)	yes
[Ref.: #8783]	Pathogenicity (animal)	yes
[Ref.: #8783]	Biosafety level	2	Risk group (German classification) According to TRBA 466

Information on genomic background e.g. entries in nucleic sequence databass Sequence information

16S Sequence information:

Only first 5 entries are displayed. Click here to see all.

	Sequence accession description	Seq. accession number	Sequence length (bp)	Sequence database	Associated NCBI tax ID
[Ref.: #8783]	Prevotella intermedia strain ATCC 25611 16S ribosomal RNA gene, partial sequence	FJ792535	1370	ENA	1122984 tax ID
[Ref.: #67770]	Prevotella intermedia gene for 16S ribosomal RNA, partial sequence, strain: JCM 11150	AB547687	1380	ENA	1122984 tax ID
[Ref.: #20218]	P.intermedia gene for 16S rRNA	X73965	1459	ENA	1122984 tax ID	*
[Ref.: #20218]	Prevotella intermedia ATCC 25611 16S ribosomal RNA gene, complete sequence	L16468	1473	ENA	28131 tax ID	*
[Ref.: #20218]	Prevotella intermedia 16S-23S ribosomal RNA intergenic spacer, partial sequence	AF385927	431	ENA	1122984 tax ID	*
[Ref.: #20218]	Prevotella intermedia strain ATCC 25611 16S ribosomal RNA gene, partial sequence	AF414821	1364	ENA	1122984 tax ID	*

Genome sequence information:

Only first 5 entries are displayed. Click here to see all.

	Sequence accession description	Seq. accession number	Assembly level	Sequence database	Associated NCBI tax ID
[Ref.: #67770]	Prevotella intermedia ATCC 25611 = DSM 20706	GCA_000519165	scaffold	GenBank	1122984 tax ID
[Ref.: #67771]	Prevotella intermedia ATCC 25611 = DSM 20706	GCA_000439065	scaffold	GenBank	1122984 tax ID
[Ref.: #67771]	Prevotella intermedia NCTC13070	GCA_900455005	contig	GenBank	28131 tax ID
[Ref.: #66792]	Prevotella intermedia ATCC 25611 = DSM 20706 strain ATCC 25611	1122984.13	complete	PATRIC	1122984 tax ID	*
[Ref.: #66792]	Prevotella intermedia strain NCTC13070	28131.49	wgs	PATRIC	28131 tax ID	*
[Ref.: #66792]	Prevotella intermedia strain strain 17	28131.7	complete	PATRIC	28131 tax ID	*

[Ref.: #8783]	GC-content	43.3 mol%	sequence analysis
[Ref.: #67770]	GC-content	44.2 mol%	high performance liquid chromatography (HPLC)
[Ref.: #67771]	GC-content	43.3 mol%	genome sequence analysis

Data predicted using genome information as a basis Genome-based predictions

	Trait	Prediction	Confidence in %	In training data
	Predictions from GenomeNet Sporulation v. 1 based on: Prevotella intermedia ATCC 25611 = DSM 20706 ATCC 25611 NCBI: GCA_001953955.1
[Ref.: #69481]	spore-forming	no	100	no

	Trait	Prediction	Confidence in %	In training data
	Predictions from Diaspora project based on: Prevotella intermedia ATCC 25611 = DSM 20706 ATCC 25611 NCBI: GCA_001953955.1
[Ref.: #69480]	flagellated	no	97.282	no
[Ref.: #69480]	gram-positive	no	97.021	yes
[Ref.: #69480]	anaerobic	yes	98.913	no
[Ref.: #69480]	halophile	no	85.072	no
[Ref.: #69480]	spore-forming	no	96.868	no
[Ref.: #69480]	glucose-util	yes	81.858	no
[Ref.: #69480]	aerobic	no	98.358	yes
[Ref.: #69480]	thermophile	no	97.534	yes
[Ref.: #69480]	motile	no	92.134	no
[Ref.: #69480]	glucose-ferment	yes	53.022	no

Availability in culture collections External links

[Ref.: #8783]

Culture collection no.

DSM 20706, ATCC 25611, KCTC 15693, CCUG 24041, JCM 7365, JCM 12248, VPI 4197, JCM 11150, BCRC 14416, CIP 103682, NCTC 13070, CIP 101222, KCTC 3692

[Ref.: #81750]

SI-ID 38613

Literature:

Only first 10 entries are displayed. Click here to see all.

	Title	Authors	Journal	DOI	Year
Pathogenicity	Quorum sensing molecules regulate epithelial cytokine response and biofilm-related virulence of three Prevotella species.	Fteita D, Kononen E, Gursoy M, Ma X, Sintim HO, Gursoy UK	Anaerobe	10.1016/j.anaerobe.2018.09.001	2018	*
Metabolism	Restriction-modification mediated barriers to exogenous DNA uptake and incorporation employed by Prevotella intermedia.	Johnston CD, Skeete CA, Fomenkov A, Roberts RJ, Rittling SR	PLoS One	10.1371/journal.pone.0185234	2017	*
Pathogenicity	Agomelatine, a MT1/MT2 melatonergic receptor agonist with serotonin 5-HT2C receptor antagonistic properties, suppresses Prevotella intermedia lipopolysaccharide-induced production of proinflammatory mediators in murine macrophages.	Hyeon JY, Choi EY, Choe SH, Park HR, Choi JI, Choi IS, Kim SJ	Arch Oral Biol	10.1016/j.archoralbio.2017.05.015	2017	*
Phylogeny	Bacterial invasion into radicular dentine-an in vitro study.	Stauffacher S, Lussi A, Nietzsche S, Neuhaus KW, Eick S	Clin Oral Investig	10.1007/s00784-016-1960-7	2016	*
Metabolism	Nucleases from Prevotella intermedia can degrade neutrophil extracellular traps.	Doke M, Fukamachi H, Morisaki H, Arimoto T, Kataoka H, Kuwata H	Mol Oral Microbiol	10.1111/omi.12171	2016	*
Pathogenicity	Genistein suppresses Prevotella intermedia lipopolysaccharide-induced inflammatory response in macrophages and attenuates alveolar bone loss in ligature-induced periodontitis.	Choi EY, Bae SH, Ha MH, Choe SH, Hyeon JY, Choi JI, Choi IS, Kim SJ	Arch Oral Biol	10.1016/j.archoralbio.2015.11.019	2015	*
Pathogenicity	Intraspecies Variability Affects Heterotypic Biofilms of Porphyromonas gingivalis and Prevotella intermedia: Evidences of Strain-Dependence Biofilm Modulation by Physical Contact and by Released Soluble Factors.	Barbosa GM, Colombo AV, Rodrigues PH, Simionato MR	PLoS One	10.1371/journal.pone.0138687	2015	*
Pathogenicity	Identification of an antibacterial protein by functional screening of a human oral metagenomic library.	Arivaradarajan P, Warburton PJ, Paramasamy G, Nair SP, Allan E, Mullany P	FEMS Microbiol Lett	10.1093/femsle/fnv142	2015	*
Phylogeny	Comparative genome analysis of Prevotella intermedia strain isolated from infected root canal reveals features related to pathogenicity and adaptation.	Ruan Y, Shen L, Zou Y, Qi Z, Yin J, Jiang J, Guo L, He L, Chen Z, Tang Z, Qin S	BMC Genomics	10.1186/s12864-015-1272-3	2015	*
Metabolism	Effect of caffeic acid phenethyl ester on Prevotella intermedia lipopolysaccharide-induced production of proinflammatory mediators in murine macrophages.	Choi EY, Choe SH, Hyeon JY, Choi JI, Choi IS, Kim SJ	J Periodontal Res	10.1111/jre.12260	2015	*
Biotechnology	Effect of quercetin on the production of nitric oxide in murine macrophages stimulated with lipopolysaccharide from Prevotella intermedia.	Cho YJ, Kim SJ	J Periodontal Implant Sci	10.5051/jpis.2013.43.4.191	2013	*
Pathogenicity	Isorhamnetin inhibits Prevotella intermedia lipopolysaccharide-induced production of interleukin-6 in murine macrophages via anti-inflammatory heme oxygenase-1 induction and inhibition of nuclear factor-kappaB and signal transducer and activator of transcription 1 activation.	Jin JY, Choi EY, Park HR, Choi JI, Choi IS, Kim SJ	J Periodontal Res	10.1111/jre.12054	2013	*
Metabolism	Identification and functional analysis of the gene cluster for fructan utilization in Prevotella intermedia.	Fuse H, Fukamachi H, Inoue M, Igarashi T	Gene	10.1016/j.gene.2012.12.023	2012	*
Cultivation	Contribution of hly homologs to the hemolytic activity of Prevotella intermedia.	Suzuki N, Fukamachi H, Arimoto T, Yamamoto M, Igarashi T	Anaerobe	10.1016/j.anaerobe.2012.04.005	2012	*
Pathogenicity	Human neutrophil defensins and their effect on epithelial cells.	Gursoy UK, Kononen E, Luukkonen N, Uitto VJ	J Periodontol	10.1902/jop.2012.120017	2012	*
Pathogenicity	Anti-inflammatory effects and the underlying mechanisms of action of daidzein in murine macrophages stimulated with Prevotella intermedia lipopolysaccharide.	Choi EY, Jin JY, Lee JY, Choi JI, Choi IS, Kim SJ	J Periodontal Res	10.1111/j.1600-0765.2011.01422.x	2011	*
Metabolism	Comparison of the virulence of exopolysaccharide-producing Prevotella intermedia to exopolysaccharide non-producing periodontopathic organisms.	Yamanaka T, Yamane K, Furukawa T, Matsumoto-Mashimo C, Sugimori C, Nambu T, Obata N, Walker CB, Leung KP, Fukushima H	BMC Infect Dis	10.1186/1471-2334-11-228	2011	*
Biotechnology	Curcumin suppresses the production of interleukin-6 in Prevotella intermedia lipopolysaccharide-activated RAW 264.7 cells.	Kim SJ	J Periodontal Implant Sci	10.5051/jpis.2011.41.3.157	2011	*
Enzymology	Molecular basis of indole production catalyzed by tryptophanase in the genus Prevotella.	Sasaki-Imamura T, Yoshida Y, Suwabe K, Yoshimura F, Kato H	FEMS Microbiol Lett	10.1111/j.1574-6968.2011.02329.x	2011	*
Metabolism	Effects of luteolin on the release of nitric oxide and interleukin-6 by macrophages stimulated with lipopolysaccharide from Prevotella intermedia.	Choi EY, Jin JY, Choi JI, Choi IS, Kim SJ	J Periodontol	10.1902/jop.2011.100759	2011	*
Biotechnology	Leptin potentiates Prevotella intermedia lipopolysaccharide-induced production of TNF-alpha in monocyte-derived macrophages.	Kim SJ	J Periodontal Implant Sci	10.5051/jpis.2010.40.3.119	2010	*
Phylogeny	The identification of genes specific to Prevotella intermedia and Prevotella nigrescens using genomic subtractive hybridization.	Masakiyo Y, Yoshida A, Shintani Y, Takahashi Y, Ansai T, Takehara T	Anaerobe	10.1016/j.anaerobe.2009.11.003	2009	*
Enzymology	Characterization of L-cysteine desulfhydrase from Prevotella intermedia.	Yano T, Fukamachi H, Yamamoto M, Igarashi T	Oral Microbiol Immunol	10.1111/j.1399-302X.2009.00546.x	2009	*
Pathogenicity	Prevotella intermedia upregulates MMP-1 and MMP-8 expression in human periodontal ligament cells.	Guan SM, Shu L, Fu SM, Liu B, Xu XL, Wu JZ	FEMS Microbiol Lett	10.1111/j.1574-6968.2009.01748.x	2009	*
Phylogeny	Prevotella aurantiaca sp. nov., isolated from the human oral cavity.	Sakamoto M, Suzuki N, Okamoto M	Int J Syst Evol Microbiol	10.1099/ijs.0.012831-0	2009	*
Pathogenicity	Prevotella intermedia ATCC 25611 targets host cell lamellipodia in epithelial cell adhesion and invasion.	Gursoy UK, Kononen E, Uitto VJ	Oral Microbiol Immunol	10.1111/j.1399-302X.2009.00510.x	2009	*
Pathogenicity	Decreased interleukin-2 responses to Fusobacterium nucleatum and Porphyromonas gingivalis in generalized aggressive periodontitis.	Borch TS, Lobner M, Bendtzen K, Holmstrup P, Nielsen CH	J Periodontol	10.1902/jop.2009.080513	2009	*
Phylogeny	Prevotella falsenii sp. nov., a Prevotella intermedia-like organism isolated from monkey dental plaque.	Sakamoto M, Kumada H, Hamada N, Takahashi Y, Okamoto M, Bakir MA, Benno Y	Int J Syst Evol Microbiol	10.1099/ijs.0.002626-0	2009	*
Pathogenicity	Antibacterial activity of [10]-gingerol and [12]-gingerol isolated from ginger rhizome against periodontal bacteria.	Park M, Bae J, Lee DS	Phytother Res	10.1002/ptr.2473	2008	*
Pathogenicity	[Study of adherence of periodontal pathogens to collagen-treated hydroxyapatite].	Sun CJ, Yang H, Lei CF, Xu Y, Wu YF	Hua Xi Kou Qiang Yi Xue Za Zhi		2008	*
Enzymology	Prevotella intermedia induces matrix metalloproteinase-9 expression in human periodontal ligament cells.	Guan SM, Shu L, Fu SM, Liu B, Xu XL, Wu JZ	FEMS Microbiol Lett	10.1111/j.1574-6968.2008.01140.x	2008	*
Pathogenicity	The influence of molecular oxygen exposure on the biology of Prevotella intermedia, with emphasis on its antibiotic susceptibility.	dos Santos SG, Diniz CG, da Silva VL, Souza NC, de Lima FL, Bomfim MR, de Carvalho MA, Farias LM	J Appl Microbiol	10.1111/j.1365-2672.2007.03313.x	2007	*
Pathogenicity	Prevotella intermedia lipopolysaccharide stimulates release of tumor necrosis factor-alpha through mitogen-activated protein kinase signaling pathways in monocyte-derived macrophages.	Kim SJ, Choi EY, Kim EG, Shin SH, Lee JY, Choi JI, Choi IS	FEMS Immunol Med Microbiol	10.1111/j.1574-695X.2007.00318.x	2007	*
Cultivation	Production of antagonistic substance by Eikenella corrodens isolated from the oral cavity of human beings with and without periodontal disease.	Apolonio AC, Carvalho MA, Ribas RN, Sousa-Gaia LG, Santos KV, Lana MA, Nicoli JR, Farias LM	J Appl Microbiol	10.1111/j.1365-2672.2006.03211.x	2007	*
Metabolism	Hemin nutritional stress inhibits bacterial invasion of radicular dentine by two endodontic anaerobes.	Love RM	Int Endod J	10.1111/j.1365-2591.2006.01186.x	2007	*
Metabolism	Effects of sonicated Prevotella intermedia, Fusobacterium nucleatum and Lactobacillus casei extracts on interleukin-8 production by human dental pulp cells.	Thaweboon B, Thaweboon S, Choonharuangdej S, Suppakpatana P	Southeast Asian J Trop Med Public Health		2006	*
Pathogenicity	The effects of tetracycline, minocycline, doxycycline and ofloxacin on Prevotella intermedia biofilm.	Takahashi N, Ishihara K, Kimizuka R, Okuda K, Kato T	Oral Microbiol Immunol	10.1111/j.1399-302X.2006.00305.x	2006	*
Metabolism	Antimicrobial actions of benzimidazoles against the oral anaerobes Fusobacterium nucleatum and Prevotella intermedia.	Sheng J, Nguyen PT, Baldeck JD, Olsson J, Marquis RE	Arch Oral Biol	10.1016/j.archoralbio.2006.05.002	2006	*
Pathogenicity	Antimicrobial effect in vitro of chlorhexidine and calcium hydroxide impregnated gutta-percha points.	Bozza FL, Molgatini SL, Perez SB, Tejerina DP, Perez Tito RI, Kaplan AE	Acta Odontol Latinoam		2005	*
Pathogenicity	The efficacy of povidone-iodine products against periodontopathic bacteria.	Nakagawa T, Hosaka Y, Ishihara K, Hiraishi T, Sato S, Ogawa T, Kamoi K	Dermatology	10.1159/000089208	2006	*
Pathogenicity	Prevotella intermedia lipopolysaccharide stimulates release of nitric oxide by inducing expression of inducible nitric oxide synthase.	Kim SJ, Ha MS, Choi EY, Choi JI, Choi IS	J Periodontal Res	10.1111/j.1600-0765.2004.00757.x	2004	*
Metabolism	In vitro activation of the hemolysin in Prevotella nigrescens ATCC 33563 and Prevotella intermedia ATCC 25611.	Silva TA, Noronha FS, de Macedo Farias L, Carvalho MA	Res Microbiol	10.1016/j.resmic.2003.09.010	2004	*
Pathogenicity	Coronal microleakage assessed by polymicrobial markers.	Britto LR, Grimaudo NJ, Vertucci FJ	J Contemp Dent Pract	1526-3711-112	2003	*
Enzymology	Chemical structure and immunobiological activity of lipid A from Prevotella intermedia ATCC 25611 lipopolysaccharide.	Hashimoto M, Asai Y, Tamai R, Jinno T, Umatani K, Ogawa T	FEBS Lett	10.1016/s0014-5793(03)00414-9	2003	*
Enzymology	Purification and partial characterization of a dipeptidyl peptidase from Prevotella intermedia.	Shibata Y, Miwa Y, Hirai K, Fujimura S	Oral Microbiol Immunol	10.1034/j.1399-302x.2003.00057.x	2003	*
Metabolism	Cleavage of CD14 and LBP by a protease from Prevotella intermedia.	Deschner J, Singhal A, Long P, Liu CC, Piesco N, Agarwal S	Arch Microbiol	10.1007/s00203-003-0548-1	2003	*
Pathogenicity	In vitro effect of laser irradiation on cementum-bound endotoxin isolated from periodontally diseased roots.	Liu CM, Shyu YC, Pei SC, Lan WH, Hou LT	J Periodontol	10.1902/jop.2002.73.11.1260	2002	*
Metabolism	Monocytic cell activation by Nonendotoxic glycoprotein from Prevotella intermedia ATCC 25611 is mediated by toll-like receptor 2.	Sugawara S, Yang S, Iki K, Hatakeyama J, Tamai R, Takeuchi O, Akashi S, Espevik T, Akira S, Takada H	Infect Immun	10.1128/IAI.69.8.4951-4957.2001	2001	*
Pathogenicity	Inflammatory cytokine production and specific antibody responses to lipopolysaccharide from endodontopathic black-pigmented bacteria in patients with multilesional periapical periodontitis.	Matsushita K, Tajima T, Tomita K, Takada H, Nagaoka S, Torii M	J Endod	10.1016/S0099-2399(99)80299-4	1999	*
Phylogeny	Survey for collagenase gene prtC in Porphyromonas gingivalis and Porphyromonas endodontalis isolated from endodontic infections.	Odell LJ, Baumgartner JC, Xia T, David LL	J Endod	10.1016/S0099-2399(99)80379-3	1999	*
Phylogeny	Isolation, cloning, and expression of an acid phosphatase containing phosphotyrosyl phosphatase activity from Prevotella intermedia.	Chen X, Ansai T, Awano S, Iida T, Barik S, Takehara T	J Bacteriol	10.1128/JB.181.22.7107-7114.1999	1999	*
Phylogeny	Use of PCR and sodium dodecyl sulfate-polyacrylamide gel electrophoresis techniques for differentiation of Prevotella intermedia sensu stricto and Prevotella nigrescens.	Premaraj T, Kato N, Fukui K, Kato H, Watanabe K	J Clin Microbiol	10.1128/JCM.37.4.1057-1061.1999	1999	*
Pathogenicity	Dual regulatory effects of interferon-alpha, -beta, and -gamma on interleukin-8 gene expression by human gingival fibroblasts in culture upon stimulation with lipopolysaccharide from Prevotella intermedia, interleukin-1alpha, or tumor necrosis factor-alpha.	Sakuta T, Tokuda M, Tamura M, Jimi E, Ikebe T, Koba T, Nagaoka S, Takada H	J Dent Res	10.1177/00220345980770080701	1998	*
Enzymology	Purification and characterization of alkaline phosphatase containing phosphotyrosyl phosphatase activity from the bacterium Prevotella intermedia.	Ansai T, Awano S, Chen X, Fuchi T, Arimoto T, Akifusa S, Takehara T	FEBS Lett	10.1016/s0014-5793(98)00514-6	1998	*
Phylogeny	Biochemical and genetic characterization of a Prevotella intermedia/nigrescens-like organism.	Kononen E, Matto J, Vaisanen-Tunkelrott ML, Frandsen EV, Helander I, Asikainen S, Finegold SM, Jousimies-Somer H	Int J Syst Bacteriol	10.1099/00207713-48-1-39	1998	*
Pathogenicity	Acid tolerance response and survival by oral bacteria.	Svensater G, Larsson UB, Greif EC, Cvitkovitch DG, Hamilton IR	Oral Microbiol Immunol	10.1111/j.1399-302x.1997.tb00390.x	1997	*
Pathogenicity	Anti-bacterial action of onion (Allium cepa L.) extracts against oral pathogenic bacteria.	Kim JH	J Nihon Univ Sch Dent	10.2334/josnusd1959.39.136	1997	*
Pathogenicity	A novel component different from endotoxin extracted from Prevotella intermedia ATCC 25611 activates lymphoid cells from C3H/HeJ mice and gingival fibroblasts from humans.	Iki K, Kawahara K, Sawamura S, Arakaki R, Sakuta T, Sugiyama A, Tamura H, Sueda T, Hamada S, Takada H	Infect Immun	10.1128/iai.65.11.4531-4538.1997	1997	*
Metabolism	Fermentation product analysis in the identification of black-pigmented bacteria from periodontitis.	Takada K, Hirasawa M	Microbios		1997	*
Pathogenicity	Effect of periodontal treatments on serum IgG antibody titers against periodontopathic bacteria.	Horibe M, Watanabe H, Ishikawa I	J Clin Periodontol	10.1111/j.1600-051x.1995.tb00798.x	1995	*
Enzymology	Properties of alkaline phosphatase in the gingival crevicular fluid.	Kina JR, Yoshida N, Goseki M, Sasaki S, Ishikawa I	Bull Tokyo Med Dent Univ		1995	*
Pathogenicity	Immunobiological activities of a 55-kilodalton cell surface protein of Prevotella intermedia ATCC 25611.	Matsushita K, Nagaoka S, Arakaki R, Kawabata Y, Iki K, Kawagoe M, Takada H	Infect Immun	10.1128/iai.62.6.2459-2469.1994	1994	*
Phylogeny	Biochemical and chemical studies on strains designated Prevotella intermedia and proposal of a new pigmented species, Prevotella nigrescens sp. nov.	Shah HN, Gharbia SE	Int J Syst Bacteriol	10.1099/00207713-42-4-542	1992	*
Phylogeny	Phenotypic characteristics and DNA relatedness in Prevotella intermedia and similar organisms.	Fukushima H, Moroi H, Inoue J, Onoe T, Ezaki T, Yabuuchi E, Leung KP, Walker CB, Clark WB, Sagawa H	Oral Microbiol Immunol	10.1111/j.1399-302x.1992.tb00023.x	1992	*
Phylogeny	Isolation and purification of bacteriocin from Prevotella intermedia (Bacteroides intermedius).	Takada K, Hirasawa M, Ikeda T	J Periodontol	10.1902/jop.1991.62.7.439	1991	*
Pathogenicity	[Mitogenic activity of lipopolysaccharide from Bacteroides intermedius against C3H/HeJ mice spleen cells].	Yamamoto M, Ono K, Mochizuki S, Nishihara Y, Makimura M, Otake S	Nichidai Koko Kagaku		1990	*
Pathogenicity	Surface appendages, hemagglutination, and adherence to human epithelial cells of Bacteroides intermedius.	Leung KP, Fukushima H, Sagawa H, Walker CB, Clark WB	Oral Microbiol Immunol	10.1111/j.1399-302x.1989.tb00253.x	1989	*
Metabolism	[Effects of endotoxins from periodontopathic bacteria on the collagen metabolism of cultured normal human gingival fibroblasts].	Tagata Y	Nihon Shishubyo Gakkai Kaishi	10.2329/perio.31.755	1989	*
Pathogenicity	[Toxicity of Bacteroides intermedius surface extracts against mouse splenic lymphocyte].	Kuroki T, Kato H, Nishihara Y, Nakagawa S, Makimura M, Otake S	Nichidai Koko Kagaku		1989	*
Phylogeny	The use of whole-cell DNA probes for the identification of Bacteroides intermedius isolates in a dot blot assay.	Moncla BJ, Strockbine L, Braham P, Karlinsey J, Roberts MC	J Dent Res	10.1177/00220345880670100401	1988	*
Genetics	Genomic and phenotypic comparison of Prevotella intermedia strains possessing different virulence in vivo.	Kwack KH, Jang EY, Yang SB, Lee JH, Moon JH	Virulence	10.1080/21505594.2022.2095718	2022	*
	In vitro antimicrobial effect of chloroaluminum phthalocyanine nanoemulsion on periodontal bacteria.	Rey LPL, Pinto SML, Muelhmann LA, Mendez LM, Sandoval LVH	J Indian Soc Periodontol	10.4103/jisp.jisp_433_20	2021	*
	Influence of different ceramic materials and surface treatments on the adhesion of Prevotella intermedia.	Poole SF, Pitondo-Silva A, Oliveira-Silva M, Moris ICM, Gomes EA	J Mech Behav Biomed Mater	10.1016/j.jmbbm.2020.104010	2020	*
	Antimicrobial Activity of Piper marginatum Jacq and Ilex guayusa Loes on Microorganisms Associated with Periodontal Disease.	Gamboa F, Munoz CC, Numpaque G, Sequeda-Castaneda LG, Gutierrez SJ, Tellez N	Int J Microbiol	10.1155/2018/4147383	2018	*
	IL-17 is involved in bone resorption in mouse periapical lesions.	Oseko F, Yamamoto T, Akamatsu Y, Kanamura N, Iwakura Y, Imanishi J, Kita M	Microbiol Immunol	10.1111/j.1348-0421.2009.00123.x	2009	*
	Susceptibility of Prevotella intermedia/Prevotella nigrescens (and Porphyromonas gingivalis) to propolis (bee glue) and other antimicrobial agents.	Santos FA, Bastos EM, Rodrigues PH, de Uzeda M, de Carvalho MA, Farias Lde M, Moreira ES	Anaerobe	10.1006/anae.2002.0411	2002	*

References

#8783

Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 20706

#20215

Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )

#20218

Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )

#47910 Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 24041

#66792

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#67770 Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#67771 Korean Collection for Type Cultures (KCTC) ; Curators of the KCTC;

#68367

Automatically annotated from API 20A .

#68380

Automatically annotated from API rID32A .

#69479

João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .

#69480

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#69481

Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch: Predictions based on the model GenomeNet Sporulation v. 1 . ( DOI 10.21203/rs.3.rs-2527258/v1 )

#81750

Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.: StrainInfo: A central database for resolving microbial strain identifiers . ( DOI 10.60712/SI-ID38613.1 )

* These data were automatically processed and therefore are not curated

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Prevotella intermedia ATCC 25611 = DSM 20706 ATCC 25611

Prevotella intermedia ATCC 25611 = DSM 20706 ATCC 25611

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