Porphyromonas endodontalis (DSM 24491, ATCC 35406, JCM 8526)

Name: Porphyromonas endodontalis (DSM 24491, ATCC 35406, JCM 8526)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 12509

Type strain

Strain Designation HG370

Culture col. no. DSM 24491 ATCC 35406 JCM 8526 NCTC 13058 CCUG 16442 2 more

NCBI tax ID(s) 553175 28124

Special Collections DSMZ CCUG JCM

History <- NCTC; NCTC 13058 <- T. J. M. van Steenbergen; HG370 Tokyo Med. Dent. Univ. <-- ATCC 35406 <-- T. J. M. van Steenbergen HG 370.

Links

Porphyromonas endodontalis HG370 is an anaerobe bacterium that was isolated from infected dental root canal.

anaerobe genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 45021

ATCC 35406,CCUG 16442,CCUG 17324,CCUG 29148,CCUG 29541,BCRC 14492,CCRC 14492,NCTC 13058,JCM 8526,DSM 24491

@ref 20215

Last LPSN update 2026-02-09 11:20:51

Domain Bacteria

Phylum Bacteroidota

Class Bacteroidia

Order Bacteroidales

Family Porphyromonadaceae

Genus Porphyromonas

Species Porphyromonas endodontalis

Full scientific name Porphyromonas endodontalis (van Steenbergen et al. 1984) Shah and Collins 1988

Synonyms (1)

Bacteroides endodontalis

Morphology

Cell morphology

@ref	Gram stain	Confidence
125439	negative	99.2
125438	negative	94.262

Colony morphology

@ref	Incubation period
17688	1-2 days
46485	6-8 days

Culture and growth conditions

Culture medium

@ref	Name	Growth	Medium link	Composition
17688	COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)		Medium recipe at MediaDive	Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base
17688	CHOPPED MEAT MEDIUM WITH CARBOHYDRATES (DSMZ Medium 110)		Medium recipe at MediaDive	Name: CHOPPED MEAT MEDIUM WITH CARBOHYDRATES (DSMZ Medium 110) Composition: Ground beef 500.0 g/l Casitone 30.0 g/l Agar 15.0 g/l K2HPO4 5.0 g/l Yeast extract 5.0 g/l D-Glucose 4.0 g/l Starch 1.0 g/l Maltose 1.0 g/l Cellobiose 1.0 g/l L-Cysteine HCl 0.5 g/l Ethanol 0.19 g/l Vitamin K3 0.05 g/l Hemin 0.005 g/l Sodium resazurin 0.0005 g/l Vitamin K1 NaOH Distilled water

Culture temp

@ref	Growth	Type	Temperature (°C)
17688	positive	growth	37
46485	positive	growth	37
67770	positive	growth	37

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
17688	anaerobe
46485	anaerobe
125438	anaerobe	92.07
125439	anaerobe	96.3

Spore formation

@ref	Spore formation	Confidence
125439		99.8
125438		94.724

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68380	29016 ChEBI	arginine	-	hydrolysis	from API rID32A
68367	17057 ChEBI	cellobiose	-	builds acid from	from API 20A
68380	16024 ChEBI	D-mannose	-	fermentation	from API rID32A
68367	65327 ChEBI	D-xylose	-	builds acid from	from API 20A
68367	5291 ChEBI	gelatin	+	hydrolysis	from API 20A
68367	30849 ChEBI	L-arabinose	-	builds acid from	from API 20A
68380	29985 ChEBI	L-glutamate	-	degradation	from API rID32A
68367	62345 ChEBI	L-rhamnose	-	builds acid from	from API 20A
68367	6731 ChEBI	melezitose	-	builds acid from	from API 20A
68380	17632 ChEBI	nitrate	-	reduction	from API rID32A
68380	16634 ChEBI	raffinose	-	fermentation	from API rID32A
68367	16634 ChEBI	raffinose	-	builds acid from	from API 20A
68367	17814 ChEBI	salicin	-	builds acid from	from API 20A
68367	30911 ChEBI	sorbitol	-	builds acid from	from API 20A
68380	27897 ChEBI	tryptophan	+	energy source	from API rID32A
68380	16199 ChEBI	urea	-	hydrolysis	from API rID32A
68367	16199 ChEBI	urea	-	hydrolysis	from API 20A

Metabolite production

@ref	Chebi-ID	Metabolite	Production
68380	35581 ChEBI	indole		from API rID32A

Metabolite tests

@ref	Chebi-ID	Metabolite	Indole test
68380	35581 ChEBI	indole	+	from API rID32A

Enzymes

@ref	Value	Activity	Ec
68380	alanine arylamidase	+	3.4.11.2	from API rID32A
68380	alkaline phosphatase	+	3.1.3.1	from API rID32A
68380	alpha-arabinosidase	-	3.2.1.55	from API rID32A
68380	alpha-fucosidase	-	3.2.1.51	from API rID32A
68380	alpha-galactosidase	-	3.2.1.22	from API rID32A
68380	alpha-glucosidase	-	3.2.1.20	from API rID32A
68380	arginine dihydrolase	-	3.5.3.6	from API rID32A
68380	beta-galactosidase	-	3.2.1.23	from API rID32A
68380	beta-Galactosidase 6-phosphate	-		from API rID32A
68380	beta-glucosidase	-	3.2.1.21	from API rID32A
68380	beta-glucuronidase	-	3.2.1.31	from API rID32A
68367	gelatinase	+		from API 20A
68380	glutamate decarboxylase	-	4.1.1.15	from API rID32A
68380	glycin arylamidase	-		from API rID32A
68380	histidine arylamidase	-		from API rID32A
68380	L-arginine arylamidase	-		from API rID32A
68380	leucine arylamidase	-	3.4.11.1	from API rID32A
68380	leucyl glycin arylamidase	+	3.4.11.1	from API rID32A
68380	phenylalanine arylamidase	-		from API rID32A
68380	proline-arylamidase	-	3.4.11.5	from API rID32A
68380	pyrrolidonyl arylamidase	-	3.4.19.3	from API rID32A
68380	serine arylamidase	-		from API rID32A
68380	tryptophan deaminase	+	4.1.99.1	from API rID32A
68380	tyrosine arylamidase	-		from API rID32A
68380	urease	-	3.5.1.5	from API rID32A
68367	urease	-	3.5.1.5	from API 20A

Pathway annotation

Computationally determined by

@ref	pathway	enzyme coverage	annotated reactions
66794	biotin biosynthesis	100	4 of 4
66794	anapleurotic synthesis of oxalacetate	100	1 of 1
66794	adipate degradation	100	2 of 2
66794	folate polyglutamylation	100	1 of 1
66794	coenzyme A metabolism	100	4 of 4
66794	UDP-GlcNAc biosynthesis	100	3 of 3
66794	CDP-diacylglycerol biosynthesis	100	2 of 2
66794	chorismate metabolism	88.89	8 of 9
66794	NAD metabolism	88.89	16 of 18
66794	lipid A biosynthesis	88.89	8 of 9
66794	CO2 fixation in Crenarchaeota	88.89	8 of 9
66794	C4 and CAM-carbon fixation	87.5	7 of 8
66794	palmitate biosynthesis	86.36	19 of 22
66794	propanol degradation	85.71	6 of 7
66794	peptidoglycan biosynthesis	80	12 of 15
66794	vitamin B12 metabolism	79.41	27 of 34
66794	photosynthesis	78.57	11 of 14
66794	tetrahydrofolate metabolism	78.57	11 of 14
66794	d-mannose degradation	77.78	7 of 9
66794	vitamin B1 metabolism	76.92	10 of 13
66794	butanoate fermentation	75	3 of 4
66794	ppGpp biosynthesis	75	3 of 4
66794	glycogen biosynthesis	75	3 of 4
66794	acetate fermentation	75	3 of 4
66794	gluconeogenesis	75	6 of 8
66794	sulfopterin metabolism	75	3 of 4
66794	flavin biosynthesis	73.33	11 of 15
66794	vitamin B6 metabolism	72.73	8 of 11
66794	cardiolipin biosynthesis	71.43	5 of 7
66794	propionate fermentation	70	7 of 10
66794	pyrimidine metabolism	68.89	31 of 45
66794	acetoin degradation	66.67	2 of 3
66794	serine metabolism	66.67	6 of 9
66794	formaldehyde oxidation	66.67	2 of 3
66794	L-lactaldehyde degradation	66.67	2 of 3
66794	purine metabolism	65.96	62 of 94
66794	pentose phosphate pathway	63.64	7 of 11
66794	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	62.5	5 of 8
66794	alanine metabolism	62.07	18 of 29
66794	glutamate and glutamine metabolism	60.71	17 of 28
66794	threonine metabolism	60	6 of 10
66794	lipoate biosynthesis	60	3 of 5
66794	isoprenoid biosynthesis	57.69	15 of 26
66794	ubiquinone biosynthesis	57.14	4 of 7
66794	aspartate and asparagine metabolism	55.56	5 of 9
66794	glycolysis	52.94	9 of 17
66794	suberin monomers biosynthesis	50	1 of 2
66794	dTDPLrhamnose biosynthesis	50	4 of 8
66794	selenocysteine biosynthesis	50	3 of 6
66794	cis-vaccenate biosynthesis	50	1 of 2
66794	aminopropanol phosphate biosynthesis	50	1 of 2
66794	isoleucine metabolism	50	4 of 8
66794	non-pathway related	50	19 of 38
66794	ethanol fermentation	50	1 of 2
66794	quinate degradation	50	1 of 2
66794	pantothenate biosynthesis	50	3 of 6
66794	citric acid cycle	50	7 of 14
66794	kanosamine biosynthesis II	50	1 of 2
66794	lysine metabolism	47.62	20 of 42
66794	phenylalanine metabolism	46.15	6 of 13
66794	histidine metabolism	44.83	13 of 29
66794	degradation of aromatic, nitrogen containing compounds	41.67	5 of 12
66794	methylglyoxal degradation	40	2 of 5
66794	glycogen metabolism	40	2 of 5
66794	O-antigen biosynthesis	40	2 of 5
66794	tryptophan metabolism	39.47	15 of 38
66794	polyamine pathway	39.13	9 of 23
66794	methionine metabolism	38.46	10 of 26
66794	phenylpropanoid biosynthesis	38.46	5 of 13
66794	ketogluconate metabolism	37.5	3 of 8
66794	oxidative phosphorylation	36.26	33 of 91
66794	lipid metabolism	35.48	11 of 31
66794	molybdenum cofactor biosynthesis	33.33	3 of 9
66794	acetyl CoA biosynthesis	33.33	1 of 3
66794	cyanate degradation	33.33	1 of 3
66794	glycolate and glyoxylate degradation	33.33	2 of 6
66794	valine metabolism	33.33	3 of 9
66794	1,4-dihydroxy-6-naphthoate biosynthesis	33.33	2 of 6
66794	IAA biosynthesis	33.33	1 of 3
66794	arginine metabolism	33.33	8 of 24
66794	nitrate assimilation	33.33	3 of 9
66794	octane oxidation	33.33	1 of 3
66794	leucine metabolism	30.77	4 of 13
66794	urea cycle	30.77	4 of 13
66794	Entner Doudoroff pathway	30	3 of 10
66794	glycine metabolism	30	3 of 10
66794	heme metabolism	28.57	4 of 14
66794	degradation of pentoses	28.57	8 of 28
66794	reductive acetyl coenzyme A pathway	28.57	2 of 7
66794	arachidonic acid metabolism	27.78	5 of 18
66794	ascorbate metabolism	27.27	6 of 22
66794	d-xylose degradation	27.27	3 of 11
66794	metabolism of disaccharids	27.27	3 of 11
66794	proline metabolism	27.27	3 of 11
66794	cyclohexanol degradation	25	1 of 4
66794	lactate fermentation	25	1 of 4
66794	degradation of sugar alcohols	25	4 of 16
66794	CMP-KDO biosynthesis	25	1 of 4
66794	sulfate reduction	23.08	3 of 13
66794	phosphatidylethanolamine bioynthesis	23.08	3 of 13
66794	cysteine metabolism	22.22	4 of 18
66794	degradation of hexoses	22.22	4 of 18
66794	glutathione metabolism	21.43	3 of 14
66794	tyrosine metabolism	21.43	3 of 14

API 20A

@ref	IND	URE	GLU	MAN	LAC	SAC	MAL	SAL	XYL	ARA	GEL	ESC	GLY	CEL	MNE	MLZ	RAF	SOR	RHA	TRE	CAT	Spores presentSPOR	GramGRAM	Morphology coccus="+" rod="-"COCC
17688	+	-	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.
17688	-	-	+	+	+	+	+	-	-	-	+	+/-	+	-	+	-	-	-	-	+	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.

API rID32A

@ref	URE	ADH (Arg)	alpha GAL	beta GAL	beta-Galactosidase 6-phosphatebeta GP	alpha GLU	beta GLU	alpha ARA	beta GUR	beta-N-Acetyl-beta-glucosaminidasebeta NAG	MNE	RAF	GDC	alpha FUC	Reduction of nitrateNIT	IND	PAL	L-arginine arylamidaseArgA	ProA	LGA	Phenylalanine arylamidasePheA	Leucine arylamidaseLeuA	PyrA	Tyrosine arylamidaseTyrA	Alanine arylamidaseAlaA	Glycin arylamidaseGlyA	Histidine arylamidaseHisA	Glutamyl-glutamate arylamidaseGGA	Serine arylamidaseSerA
17688	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	+	-	-	+	-	-	-	-	+	-	-	-	-
17688	-	-	-	-	-	-	-	-	-	+/-	-	-	-	-	-	+	+	-	-	+	-	-	-	-	+	-	-	+/-	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Infection	#Disease	-
#Host Body-Site	#Oral cavity and airways	#Tooth

Isolation

@ref	Sample type	Geographic location	Country	Country ISO 3 Code	Continent
17688	infected dental root canal	Amsterdam	Netherlands	NLD	Europe
46485	Infected root canal
67770	Infected root canal

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
17688	2	Risk group (German classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
124043	ASM2009737v1 assembly for Porphyromonas endodontalis FDAARGOS_1506	complete	GCA_020097375	28124.79	8120649103	28124	98.04
66792	Porphyromonas endodontalis strain FDAARGOS_1506	complete		28124.82		28124	96.52
66792	Porphyromonas endodontalis strain FDAARGOS_1506	complete		28124.80		28124	96.52
66792	Porphyromonas endodontalis strain FDAARGOS_1506	complete		28124.81		28124	96.52
67770	52278_C01 assembly for Porphyromonas endodontalis NCTC13058	contig	GCA_900454815	28124.3	2858648101	28124	78.13
67770	ASM17481v1 assembly for Porphyromonas endodontalis ATCC 35406	contig	GCA_000174815	553175.3	643886148	553175	71.43

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Porphyromonas endodontalis gene for 16S ribosomal RNA, partial sequence, strain: JCM 8526	AB547659	1435	28124
20218	Porphyromonas endodontalis strain ATCC 35406 16S-23S ribosomal RNA intergenic spacer, partial sequence	AY546477	735	28124
20218	Porphyromonas endodontalis ATCC 35406 16S ribosomal RNA gene, complete sequence	L16491	1475	28124
17688	Porphyromonas endodontalis ATCC 35406 16S ribosomal RNA gene, partial sequence	AY253728	1441	28124

GC content

@ref	GC-content (mol%)	Method
17688	47.5	sequence analysis
67770	49.6	thermal denaturation, midpoint method (Tm)

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Porphyromonas endodontalis strain FDAARGOS_1506
PATRIC: 28124.79

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	no	99.80	no
125439	motility	BacteriaNetⓘ	no	72.20	no
125439	gram_stain	BacteriaNetⓘ	negative	99.20	no
125439	oxygen_tolerance	BacteriaNetⓘ	anaerobe	96.30	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Porphyromonas endodontalis strain FDAARGOS_1506 strain Not applicable
PATRIC: 28124.79

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	no	94.26	no
125438	anaerobic	anaerobicⓘ	yes	92.07	yes
125438	spore-forming	spore-formingⓘ	no	94.72	no
125438	thermophilic	thermophileⓘ	no	91.45	yes
125438	aerobic	aerobicⓘ	no	97.68	yes
125438	flagellated	motile2+ⓘ	no	87.00	no

Literature

Topic	Title	Authors	Journal	DOI	Year
Pathogenicity	Lipopolysaccharides from Porphyromonas endodontalis and Porphyromonas gingivalis promote angiogenesis via Toll-like-receptors 2 and 4 pathways in vitro.	Fernandez A, Herrera D, Hoare A, Hernandez M, Torres VA.	Int Endod J	10.1111/iej.13957	2023
	Periodontal Health in Individuals Living with HIV: An Exploratory and Descriptive Molecular Approach of Microbial Interspecific and Intraspecific Diversity in Brazilian Patients.	Ponce PNO, Chaves LB, Perce-da-Silva DS, Carneiro-Alencar AL, Rodolphi CM, Soares IF, Rodrigues-da-Silva RN, Alves-da-Silva AC, Marques FV, Peres RV, Ferreira DC, de Souza RC, Goncalves C, Goncalves LS, Lima-Junior JDC.	Microorganisms	10.3390/microorganisms13040867	2025
	Bifidobacterium animalis subsp. lactis HN019 has antimicrobial activity against endodontic pathogens in vitro.	Araujo LDC, da Silva RAB, Silva CMPC, Salvador SLS, Messora MR, Furlaneto FAC, Mastrange MDA, Pucinelli CM, da Silva LAB.	Braz J Microbiol	10.1007/s42770-023-01083-2	2023
	Antibodies with specificity to glycan motifs that decorate OMV cargo proteins.	Kim HY, Rothenberger CM, Davey ME, Yu M.	mSphere	10.1128/msphere.00907-24	2025
	Porphyromonas endodontalis HmuY differentially participates in heme acquisition compared to the Porphyromonas gingivalis and Tannerella forsythia hemophore-like proteins.	Smiga M, Olczak T.	Front Cell Infect Microbiol	10.3389/fcimb.2024.1421018	2024
Pathogenicity	Lipopolysaccharide from Porphyromonas gingivalis, but Not from Porphyromonas endodontalis, Induces Macrophage M1 Profile.	Veloso P, Fernandez A, Astorga J, Gonzalez-Quintanilla D, Castro A, Escobar A, Hoare A, Hernandez M.	Int J Mol Sci	10.3390/ijms231710011	2022
	Porphyromonas gingivalis extracellular vesicles exacerbated osteoporosis by disrupting osteoblast mitochondrial dynamics and inhibiting Cpt2-regulated fatty acid oxidation.	Qiu Q, Yan X, Zhang Z, Zhang X, Ma J, Gao W, An N, Qiu L, Guo J.	J Nanobiotechnology	10.1186/s12951-025-03717-z	2025
	Effectiveness of Herbal Medicines with Anti-Inflammatory, Antimicrobial, and Antioxidant Properties in Improving Oral Health and Treating Gingivitis and Periodontitis: A Systematic Review.	Malcangi G, Inchingolo AM, Casamassima L, Trilli I, Ferrante L, Inchingolo F, Palermo A, Inchingolo AD, Dipalma G.	Nutrients	10.3390/nu17050762	2025
	Antimicrobial and Antibiofilm Effect of Brazilian Green Propolis Aqueous Extract against Dental Anaerobic Bacteria.	de Sa Assis MA, de Paula Ramos L, Abu Hasna A, de Queiroz TS, Pereira TC, Nagai de Lima PM, Berretta AA, Marcucci MC, Talge Carvalho CA, de Oliveira LD.	Molecules	10.3390/molecules27238128	2022
	Antimicrobial Action, Genotoxicity, and Morphological Analysis of Three Calcium Silicate-Based Cements.	Abu Hasna A, Theodoro AL, Pereira LM, Ramos LP, Campos TMB, Ala Rachi M, Al-Nahalwi T, de Oliveira LD, Carvalho CAT.	Biomed Res Int	10.1155/2022/2155226	2022
	Systemic and Extraradicular Bacterial Translocation in Apical Periodontitis.	Bordagaray MJ, Fernandez A, Garrido M, Astorga J, Hoare A, Hernandez M.	Front Cell Infect Microbiol	10.3389/fcimb.2021.649925	2021
	Novel bioactive nanospheres show effective antibacterial effect against multiple endodontic pathogens.	Liu J, Wu H, Qiu J, Yang S, Xiang D, Zhang X, Kuang J, Xiao M, Yu Q, Cheng X.	Heliyon	10.1016/j.heliyon.2024.e28266	2024
	The antibacterial activity of mineral trioxide aggregate containing calcium fluoride.	Lim M, Yoo S.	J Dent Sci	10.1016/j.jds.2021.09.005	2022
	Serine/Glycine Lipid Recovery in Lipid Extracts From Healthy and Diseased Dental Samples: Relationship to Chronic Periodontitis.	Nichols FC, Bhuse K, Clark RB, Provatas AA, Carrington E, Wang YH, Zhu Q, Davey ME, Dewhirst FE.	Front Oral Health	10.3389/froh.2021.698481	2021
	Antimicrobial activity and biocompatibility of the mixture of mineral trioxide aggregate and nitric oxide-releasing compound.	Shin JH, Ryu JJ, Lee SH.	J Dent Sci	10.1016/j.jds.2020.07.018	2021
Phylogeny	Microbial Communities in the Extraradicular and Intraradicular Infections Associated With Persistent Apical Periodontitis.	Sun X, Yang Z, Nie Y, Hou B.	Front Cell Infect Microbiol	10.3389/fcimb.2021.798367	2021
	Biological and chemical properties of five mineral oxides and of mineral trioxide aggregate repair high plasticity: an in vitro study.	Abu Hasna A, de Paula Ramos L, Campos TMB, de Castro Lopes SLP, Rachi MA, de Oliveira LD, Carvalho CAT.	Sci Rep	10.1038/s41598-022-17854-0	2022
	Comparison of antimicrobial activity of traditional and new developed root sealers against pathogens related root canal.	Shin JH, Lee DY, Lee SH.	J Dent Sci	10.1016/j.jds.2017.10.007	2018
	TLR4, NOD1 and NOD2 mediate immune recognition of putative newly identified periodontal pathogens.	Marchesan J, Jiao Y, Schaff RA, Hao J, Morelli T, Kinney JS, Gerow E, Sheridan R, Rodrigues V, Paster BJ, Inohara N, Giannobile WV.	Mol Oral Microbiol	10.1111/omi.12116	2016
	Detection of hydrogen cyanide from oral anaerobes by cavity ring down spectroscopy.	Chen W, Roslund K, Fogarty CL, Pussinen PJ, Halonen L, Groop PH, Metsala M, Lehto M.	Sci Rep	10.1038/srep22577	2016
Genetics	Comparative Genomics of the Genus Porphyromonas Identifies Adaptations for Heme Synthesis within the Prevalent Canine Oral Species Porphyromonas cangingivalis.	O'Flynn C, Deusch O, Darling AE, Eisen JA, Wallis C, Davis IJ, Harris SJ.	Genome Biol Evol	10.1093/gbe/evv220	2015
Pathogenicity	Biologic activity of porphyromonas endodontalis complex lipids.	Mirucki CS, Abedi M, Jiang J, Zhu Q, Wang YH, Safavi KE, Clark RB, Nichols FC.	J Endod	10.1016/j.joen.2014.02.017	2014
Enzymology	Bacteriological analysis of necrotic pulp and fistulae in primary teeth.	Fabris AS, Nakano V, Avila-Campos MJ.	J Appl Oral Sci	10.1590/1678-775720130358	2014
	In vitro culture of previously uncultured oral bacterial phylotypes.	Thompson H, Rybalka A, Moazzez R, Dewhirst FE, Wade WG.	Appl Environ Microbiol	10.1128/aem.02156-15	2015
Pathogenicity	Aerotolerance of an endodontic pathogen.	Thomas SJ, Eleazer PD.	J Endod	10.1097/00004770-200310000-00007	2003
	Sensitivity of Porphyromonas and Prevotella species in liquid media to argon laser.	Henry CA, Judy M, Dyer B, Wagner M, Matthews JL.	Photochem Photobiol	10.1111/j.1751-1097.1995.tb08631.x	1995
Enzymology	Real-time TaqMan PCR for quantifying oral bacteria during biofilm formation.	Suzuki N, Nakano Y, Yoshida A, Yamashita Y, Kiyoura Y.	J Clin Microbiol	10.1128/jcm.42.8.3827-3830.2004	2004
	Quantitative and qualitative analysis of microorganisms in root-filled teeth with persistent infection: Monitoring of the endodontic retreatment.	Endo MS, Ferraz CCR, Zaia AA, Almeida JFA, Gomes BPFA.	Eur J Dent	10.4103/1305-7456.115414	2013
	Monoclonal antibody against Porphyromonas (Bacteroides) endodontalis lipopolysaccharide and application of the antibody for direct identification of the species.	Hanazawa S, Sagiya T, Kitami H, Ohta K, Nishikawa H, Kitano S.	J Clin Microbiol	10.1128/jcm.29.11.2550-2553.1991	1991
Phylogeny	Single-cell enumeration of an uncultivated TM7 subgroup in the human subgingival crevice.	Ouverney CC, Armitage GC, Relman DA.	Appl Environ Microbiol	10.1128/aem.69.10.6294-6298.2003	2003
Metabolism	Fusobacterium nucleatum increases collagenase 3 production and migration of epithelial cells.	Uitto VJ, Baillie D, Wu Q, Gendron R, Grenier D, Putnins EE, Kanervo A, Firth JD.	Infect Immun	10.1128/iai.73.2.1171-1179.2005	2005
Enzymology	Detection of unculturable bacteria in periodontal health and disease by PCR.	Harper-Owen R, Dymock D, Booth V, Weightman AJ, Wade WG.	J Clin Microbiol	10.1128/jcm.37.5.1469-1473.1999	1999
	Structure of a membrane-attack complex/perforin (MACPF) family protein from the human gut symbiont Bacteroides thetaiotaomicron.	Xu Q, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Cai X, Carlton D, Chen C, Chiu HJ, Clayton T, Das D, Deller MC, Duan L, Ellrott K, Farr CL, Feuerhelm J, Grant JC, Grzechnik A, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, Krishna SS, Kumar A, Lam WW, Marciano D, Miller MD, Morse AT, Nigoghossian E, Nopakun A, Okach L, Puckett C, Reyes R, Tien HJ, Trame CB, van den Bedem H, Weekes D, Wooten T, Yeh A, Zhou J, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA.	Acta Crystallogr Sect F Struct Biol Cryst Commun	10.1107/s1744309110023055	2010
Enzymology	Rapid presumptive identification of black-pigmented gram-negative anaerobic bacteria by using 4-methylumbelliferone derivatives.	Moncla BJ, Braham P, Rabe LK, Hillier SL.	J Clin Microbiol	10.1128/jcm.29.9.1955-1958.1991	1991
	Bacterium-dependent induction of cytokines in mononuclear cells and their pathologic consequences in vivo.	Jiang Y, Magli L, Russo M.	Infect Immun	10.1128/iai.67.5.2125-2130.1999	1999
Enzymology	A novel approach for detecting an immunodominant antigen of Porphyromonas gingivalis in diagnosis of adult periodontitis.	Kawai T, Ito HO, Sakato N, Okada H.	Clin Diagn Lab Immunol	10.1128/cdli.5.1.11-17.1998	1998
	Conservation of fimbriae and the hemagglutinating adhesin HA-Ag2 among Porphyromonas gingivalis strains and other anaerobic bacteria studied by epitope mapping analysis.	Du L, Pellen-Mussi P, Chandad F, Mouton C, Bonnaure-Mallet M.	Clin Diagn Lab Immunol	10.1128/cdli.4.6.711-714.1997	1997
	Immunobiological activities of a 55-kilodalton cell surface protein of Prevotella intermedia ATCC 25611.	Matsushita K, Nagaoka S, Arakaki R, Kawabata Y, Iki K, Kawagoe M, Takada H.	Infect Immun	10.1128/iai.62.6.2459-2469.1994	1994
	Identification by subtractive hybridization of a novel insertion sequence specific for virulent strains of Porphyromonas gingivalis.	Sawada K, Kokeguchi S, Hongyo H, Sawada S, Miyamoto M, Maeda H, Nishimura F, Takashiba S, Murayama Y.	Infect Immun	10.1128/iai.67.11.5621-5625.1999	1999
Enzymology	Quantitative microbiological study of human carious dentine by culture and real-time PCR: association of anaerobes with histopathological changes in chronic pulpitis.	Martin FE, Nadkarni MA, Jacques NA, Hunter N.	J Clin Microbiol	10.1128/jcm.40.5.1698-1704.2002	2002
Enzymology	Evidence for the absence of hyaluronidase activity in Porphyromonas gingivalis.	Grenier D, Michaud J.	J Clin Microbiol	10.1128/jcm.31.7.1913-1915.1993	1993
Metabolism	Metabolic Modeling of Cystic Fibrosis Airway Communities Predicts Mechanisms of Pathogen Dominance.	Henson MA, Orazi G, Phalak P, O'Toole GA.	mSystems	10.1128/msystems.00026-19	2019
Metabolism	Identification of an O-antigen chain length regulator, WzzP, in Porphyromonas gingivalis.	Shoji M, Yukitake H, Sato K, Shibata Y, Naito M, Aduse-Opoku J, Abiko Y, Curtis MA, Nakayama K.	Microbiologyopen	10.1002/mbo3.84	2013
Phylogeny	Uncultivated phylotypes and newly named species associated with primary and persistent endodontic infections.	Siqueira JF, Rocas IN.	J Clin Microbiol	10.1128/jcm.43.7.3314-3319.2005	2005
Enzymology	Detection of Porphyromonas gingivalis from saliva by PCR by using a simple sample-processing method.	Matto J, Saarela M, Alaluusua S, Oja V, Jousimies-Somer H, Asikainen S.	J Clin Microbiol	10.1128/jcm.36.1.157-160.1998	1998
Enzymology	PCR-DNA probe assays for identification and detection of Prevotella intermedia sensu stricto and Prevotella nigrescens.	Guillot E, Mouton C.	J Clin Microbiol	10.1128/jcm.35.7.1876-1882.1997	1997
	A persistent and diverse airway microbiota present during chronic obstructive pulmonary disease exacerbations.	Huang YJ, Kim E, Cox MJ, Brodie EL, Brown R, Wiener-Kronish JP, Lynch SV.	OMICS	10.1089/omi.2009.0100	2010
Phylogeny	Use of PCR and sodium dodecyl sulfate-polyacrylamide gel electrophoresis techniques for differentiation of Prevotella intermedia sensu stricto and Prevotella nigrescens.	Premaraj T, Kato N, Fukui K, Kato H, Watanabe K.	J Clin Microbiol	10.1128/jcm.37.4.1057-1061.1999	1999
Pathogenicity	[Antimicrobial effect of a new bio-ceramic material iRoot FM on Porphyromonas endodontalis].	Bi J, Liu Y, Chen X	Shanghai Kou Qiang Yi Xue		2017
Proteome	[Analysis of virulence factors of Porphyromonas endodontalis based on comparative proteomics technique].	Li H, Ji H, Wu SS, Hou BX	Zhonghua Kou Qiang Yi Xue Za Zhi	10.3760/cma.j.issn.1002-0098.2016.12.009	2016
Phylogeny	Identification of Dipeptidyl-Peptidase (DPP)5 and DPP7 in Porphyromonas endodontalis, Distinct from Those in Porphyromonas gingivalis.	Nishimata H, Ohara-Nemoto Y, Baba TT, Hoshino T, Fujiwara T, Shimoyama Y, Kimura S, Nemoto TK	PLoS One	10.1371/journal.pone.0114221	2014
Enzymology	Asp- and Glu-specific novel dipeptidyl peptidase 11 of Porphyromonas gingivalis ensures utilization of proteinaceous energy sources.	Ohara-Nemoto Y, Shimoyama Y, Kimura S, Kon A, Haraga H, Ono T, Nemoto TK	J Biol Chem	10.1074/jbc.M111.278572	2011
Pathogenicity	Antibacterial activity of [10]-gingerol and [12]-gingerol isolated from ginger rhizome against periodontal bacteria.	Park M, Bae J, Lee DS	Phytother Res	10.1002/ptr.2473	2008
Cultivation	Invasion of vascular cells in vitro by Porphyromonas endodontalis.	Dorn BR, Harris LJ, Wujick CT, Vertucci FJ, Progulske-Fox A	Int Endod J	10.1046/j.0143-2885.2001.00489.x	2002
Enzymology	The purification and characterization of an 88-kDa Porphyromonas endodontalis 35406 protease.	Rosen G, Shoshani M, Naor R, Sela MN	Oral Microbiol Immunol	10.1034/j.1399-302x.2001.160602.x	2001
Phylogeny	Survey for collagenase gene prtC in Porphyromonas gingivalis and Porphyromonas endodontalis isolated from endodontic infections.	Odell LJ, Baumgartner JC, Xia T, David LL	J Endod	10.1016/S0099-2399(99)80379-3	1999
Metabolism	Experimental root canal infections in conventional and germ-free mice.	Sobrinho AP, Barros MH, Nicoli JR, Carvalho MA, Farias LM, Bambirra EA, Bahia MG, Vieira EC	J Endod	10.1016/S0099-2399(98)80021-6	1998
Phylogeny	Isolation and characterization of a nonpigmented variant of Porphyromonas endodontalis.	Suzuki K, Ikeda T, Nakamura H, Yoshimura F	Oral Microbiol Immunol	10.1111/j.1399-302x.1997.tb00372.x	1997
Biotechnology	[Production and characterization of specific monoclonal antibody against Porphyromonas endodontalis].	Xue Y, Sun C, Tan J	Zhonghua Kou Qiang Yi Xue Za Zhi		1995
Enzymology	Congo red binding by Porphyromonas gingivalis is mediated by a 66 kDa outer-membrane protein.	Smalley JW, Birss AJ, McKee AS, Marsh PD	Microbiology (Reading)	10.1099/00221287-141-1-205	1995
Enzymology	Characterization of total membrane protein of Porphyromonas endodontalis.	Herweijer JA, Loos BG, Neiders ME	J Endod	10.1016/s0099-2399(06)81334-8	1992
Pathogenicity	Immunochemical and biological characterization of outer membrane proteins of Porphyromonas endodontalis.	Ogawa T, Kuribayashi S, Shimauchi H, Toda T, Hamada S	Infect Immun	10.1128/iai.60.11.4528-4533.1992	1992
Pathogenicity	Humoral immune response to an antigen from Porphyromonas gingivalis 381 in periodontal disease.	Kurihara H, Nishimura F, Nakamura T, Nakagawa M, Tanimoto I, Nomura Y, Kokeguchi S, Kato K, Murayama Y	Infect Immun	10.1128/iai.59.8.2758-2762.1991	1991
Enzymology	Monoclonal antibody against a serotype antigen of Porphyromonas (Bacteroides) endodontalis and characteristics of the antigen.	Hanazawa S, Sagiya T, Amano S, Nishikawa H, Kitano S	Infect Immun	10.1128/iai.58.8.2542-2546.1990	1990
Pathogenicity	The effect of subminimal inhibitory concentrations of antimicrobial agents on three bacterial mixtures.	Lacroix JM, Mayrand D	Oral Microbiol Immunol	10.1111/j.1399-302x.1989.tb00104.x	1989
Phylogeny	Porphyromonas uenonis sp. nov., a pathogen for humans distinct from P. asaccharolytica and P. endodontalis.	Finegold SM, Vaisanen ML, Rautio M, Eerola E, Summanen P, Molitoris D, Song Y, Liu C, Jousimies-Somer H.	J Clin Microbiol	10.1128/jcm.42.11.5298-5301.2004	2004
Phylogeny	Porphyromonas somerae sp. nov., a pathogen isolated from humans and distinct from porphyromonas levii.	Summanen PH, Durmaz B, Vaisanen ML, Liu C, Molitoris D, Eerola E, Helander IM, Finegold SM.	J Clin Microbiol	10.1128/jcm.43.9.4455-4459.2005	2005
Phylogeny	Porphyromonas gingivicanis sp. nov. and Porphyromonas crevioricanis sp. nov., isolated from beagles.	Hirasawa M, Takada K	Int J Syst Bacteriol	10.1099/00207713-44-4-637	1994
Phylogeny	Porphyromonas canoris sp. nov., an asaccharolytic, black-pigmented species from the gingival sulcus of dogs.	Love DN, Karjalainen J, Kanervo A, Forsblom B, Sarkiala E, Bailey GD, Wigney DI, Jousimies-Somer H	Int J Syst Bacteriol	10.1099/00207713-44-2-204	1994

References

#17688	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 24491
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#46485	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 16442
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#66794	Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg: BRENDA, the ELIXIR core data resource in 2021: new developments and updates. Nucleic Acids Res. 49: D498 - D508 2020 ( DOI 10.1093/nar/gkaa1025 , PubMed 33211880 )
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68367	Automatically annotated from API 20A .
#68380	Automatically annotated from API rID32A .
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Porphyromonas endodontalis (DSM 24491, ATCC 35406, JCM 8526)

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Genome browser: GCA_020097375

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