Aggregatibacter actinomycetemcomitans Y4 is a microaerophile, mesophilic human pathogen that was isolated from subgingival dental plaque.
microaerophile mesophilic human pathogen genome sequence 16S sequence| @ref 20215 |
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Last LPSN update
2026-02-09 11:20:39 |
| Domain Bacteria |
| Phylum Pseudomonadota |
| Class Gammaproteobacteria |
| Order Pasteurellales |
| Family Pasteurellaceae |
| Genus Aggregatibacter |
| Species Aggregatibacter actinomycetemcomitans |
| Full scientific name Aggregatibacter actinomycetemcomitans (Klinger 1912) Nørskov-Lauritsen and Kilian 2006 |
| Synonyms (3) |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 4215 | BHI MEDIUM (DSMZ Medium 215) | Medium recipe at MediaDive  | Name: BHI MEDIUM (DSMZ Medium 215) Composition: Brain heart infusion 37.0 g/l Distilled water | ||
| 4215 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | Medium recipe at MediaDive | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base |
| 4215 | Oxygen tolerancemicroaerophile |
| @ref | PEN | GLU | FRU | MAL | SAC | ODC | URE | LIP | PAL | beta GAL | ProA | GGT | IND | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 4215 | - | + | + | + | - | - | - | - | + | - | - | + | - | |
| 4215 | + | + | - | - | - | - | - | + | - | - | + | - | - | |
| 4215 | + | + | - | - | - | - | - | + | - | - | + | - | - | |
| 4215 | + | + | + | - | - | - | - | + | - | - | + | - | - | |
| 4215 | + | + | + | + | - | - | - | + | - | - | + | - | - | |
| 4215 | - | + | + | + | +/- | - | - | - | + | - | - | + | - | |
| 4215 | - | + | + | - | - | - | - | - | + | - | - | + | - | |
| 4215 | - | + | + | - | - | - | - | - | + | - | - | + | - | |
| 4215 | - | + | + | + | + | - | - | - | + | - | - | + | - | |
| 4215 | - | + | + | + | - | - | - | - | + | - | - | + | - |
| Cat1 | Cat2 | Cat3 | |
|---|---|---|---|
| #Host Body-Site | #Oral cavity and airways | #Plaque | |
| #Host Body-Site | #Oral cavity and airways | #Tooth |
| 4215 | Sample typesubgingival dental plaque |
Global distribution of 16S sequence AB595137 (>99% sequence identity) for Aggregatibacter actinomycetemcomitans subclade from Microbeatlas 
 Aquatic Samples |
279 |
 Soil Samples |
46 |
 Animal Samples |
7969 |
 Plant Samples |
42 |
| Total Samples | 8336 |
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | IMG accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|---|
| 66792 | ASM31815v1 assembly for Aggregatibacter actinomycetemcomitans Y4 | scaffold | GCA_000318155   | 1035194.3  | 2537561947  | 1035194 | 53.61 |  |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Pathogenicity | Exploring the In Vitro Antibacterial Potential of Specific Probiotic Strains against Oral Pathogens. | Squarzanti DF, Dell'Atti F, Scalia AC, Najmi Z, Cochis A, Malfa P. | Microorganisms | 10.3390/microorganisms12030441 | 2024 | |
| Lactobacillus probiotic cell-free supernatants and vitamin D influence interleukin-6 production and mitigate oral periodontopathogens-induced cytotoxicity in FaDu cells. | Zanetta P, De Giorgis V, Barberis E, Manfredi M, Amoruso A, Pane M, Azzimonti B. | Front Microbiol | 10.3389/fmicb.2025.1578267 | 2025 | | |
| Effect of titanium implants along with silver ions and tetracycline on type I interferon-beta expression during implant-related infections in co-culture and mouse model. | Rahim MI, Waqas SF, Lienenklaus S, Willbold E, Eisenburger M, Stiesch M. | Front Bioeng Biotechnol | 10.3389/fbioe.2023.1227148 | 2023 | | |
| In Vitro Selection of Lactobacillus and Bifidobacterium Probiotic Strains for the Management of Oral Pathobiont Infections Associated to Systemic Diseases. | Zanetta P, Squarzanti DF, di Coste A, Rolla R, Valletti PA, Garzaro M, Dell'Era V, Amoruso A, Pane M, Azzimonti B. | Int J Mol Sci | 10.3390/ijms232416163 | 2022 | | |
| Pathogenicity | Effects of mechanical strain on periodontal ligament fibroblasts in presence of Aggregatibacter actinomycetemcomitans lysate. | Schroder A, Stumpf J, Paddenberg E, Neubert P, Schatz V, Kostler J, Jantsch J, Deschner J, Proff P, Kirschneck C. | BMC Oral Health | 10.1186/s12903-021-01761-3 | 2021 | |
| Non-Invasive Luciferase Imaging of Type I Interferon Induction in a Transgenic Mouse Model of Biomaterial Associated Bacterial Infections: Microbial Specificity and Inter-Bacterial Species Interactions. | Rahim MI, Winkel A, Lienenklaus S, Stumpp NS, Szafranski SP, Kommerein N, Willbold E, Reifenrath J, Mueller PP, Eisenburger M, Stiesch M. | Microorganisms | 10.3390/microorganisms8101624 | 2020 | | |
| Bacterial-Specific Induction of Inflammatory Cytokines Significantly Decreases upon Dual Species Infections of Implant Materials with Periodontal Pathogens in a Mouse Model. | Rahim MI, Winkel A, Ingendoh-Tsakmakidis A, Lienenklaus S, Falk CS, Eisenburger M, Stiesch M. | Biomedicines | 10.3390/biomedicines10020286 | 2022 | | |
| In Vitro Antibacterial Effectiveness of a Naturopathic Oral Care Product on Oral Pathogens. | Beyer A, Dalton M, Doll K, Winkel A, Stumpp NS, Stiesch M. | Oral Health Prev Dent | 10.3290/j.ohpd.a44938 | 2020 | | |
| Microleakage of Restorative Materials Used for Temporization of Endodontic Access Cavities. | Wuersching SN, Moser L, Obermeier KT, Kollmuss M. | J Clin Med | 10.3390/jcm12144762 | 2023 | | |
| Enzymology | Optimization of quantitative polymerase chain reactions for detection and quantification of eight periodontal bacterial pathogens. | Decat E, Cosyn J, De Bruyn H, Miremadi R, Saerens B, Van Mechelen E, Vermeulen S, Vaneechoutte M, Deschaght P. | BMC Res Notes | 10.1186/1756-0500-5-664 | 2012 | |
| Oil Essential Mouthwashes Antibacterial Activity against Aggregatibacter actinomycetemcomitans: A Comparison between Antibiofilm and Antiplanktonic Effects. | Erriu M, Pili FM, Tuveri E, Pigliacampo D, Scano A, Montaldo C, Piras V, Denotti G, Pilloni A, Garau V, Orru G. | Int J Dent | 10.1155/2013/164267 | 2013 | | |
| Incidence of Bacteriocins Produced by Food-Related Lactic Acid Bacteria Active towards Oral Pathogens. | Zoumpopoulou G, Pepelassi E, Papaioannou W, Georgalaki M, Maragkoudakis PA, Tarantilis PA, Polissiou M, Tsakalidou E, Papadimitriou K. | Int J Mol Sci | 10.3390/ijms14034640 | 2013 | | |
| Antimicrobial Efficacy of Nano-Hydroxyapatite-Coated Implants Against Peri-Implantitis-Associated Bacteria. | Sharma N, Shukla J, Jain S, Vyas R, Verma T, Navlani B. | J Pharm Bioallied Sci | 10.4103/jpbs.jpbs_169_25 | 2025 | | |
| Digital PCR outperforms quantitative real-time PCR for the detection and quantification of major periodontal pathobionts. | Munjakovic H, Povsic K, Poljak M, Seme K, Gaspersic R, Skubic L. | J Oral Microbiol | 10.1080/20002297.2025.2537439 | 2025 | | |
| Honey Compounds Exhibit Antibacterial Effects Against Aggregatibacter actinomycetemcomitans JP2. | Hbibi A, Ezzahi A, Ozturk F, Cremers NAJ, Kasouati J, Moussaif A, Johansson A, Zouhdi M, Toure B, Maroui I. | Antibiotics (Basel) | 10.3390/antibiotics14090887 | 2025 | | |
| Pathogenicity | Inhibition of CD38 by 78c Enhanced NAD+, Alleviated Inflammation, and Decreased Oxidative Stress in Old Murine Macrophages Induced by Oral Pathogens. | Cao K, Chowdhury N, Wellslager B, Hill WD, Yilmaz O, Yu H. | Int J Mol Sci | 10.3390/ijms26136180 | 2025 | |
| In-Vitro Inhibitory Efficacy of 3 Types of Probiotics on the Growth of Aggregatibacter actinomycetemcomitans Bacteria. | Sulistiowati CP, Suhartono M, Rahmawati DF, Ulfah N, Supandi SK, Wijaksana IKE, Abullais SS, Dhadse P. | Front Biosci (Landmark Ed) | 10.31083/j.fbl2805106 | 2023 | | |
| Assessment of Oral Microbial Viability by 2,6-Dichlorophenolindophenol a Redox Agent. | Sreenivasan PK, Haraszthy VI. | Antibiotics (Basel) | 10.3390/antibiotics14060590 | 2025 | | |
| CD38 Inhibitor 78c Attenuates Pro-Inflammatory Cytokine Expression and Osteoclastogenesis in Macrophages. | Lory W, Chowdhury N, Wellslager B, Pandruvada S, Huang Y, Yilmaz O, Yu H. | Cells | 10.3390/cells13231971 | 2024 | | |
| Antibacterial effect of a gingival patch containing nano-emulsion of red dragon fruit peel extract on Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, and Fusobacterium nucleatum assessed in vitro. | Diyatri I, Juliastuti WS, Ridwan RD, Ananda GC, Waskita FA, Juliana NV, Khansa SP, Pratiwi RT, Putri CR. | J Oral Biol Craniofac Res | 10.1016/j.jobcr.2023.03.011 | 2023 | | |
| Real-Time PCR Method as Diagnostic Tool for Detection of Periodontal Pathogens in Patients with Periodontitis. | Kuret S, Kalajzic N, Ruzdjak M, Grahovac B, Jezina Buselic MA, Sardelic S, Delic A, Susak L, Sutlovic D. | Int J Mol Sci | 10.3390/ijms25105097 | 2024 | | |
| Zinc Phosphate Microparticles against Nosocomial and Oral Bacteria: Synthesis, Analytical Characterization, and Biocompatibility. | Reyes-Carmona L, Izzi M, Picca RA, Sportelli MC, Prado-Prone G, Silva-Bermudez P, Rodil SE, Cioffi N, Almaguer-Flores A. | ACS Omega | 10.1021/acsomega.5c02071 | 2025 | | |
| In Vitro Antibacterial Activity of Myrtus communis L. and Marrubium vulgare L. Leaves against Aggregatibacter actinomycetemcomitans and Eikenella corrodens. | Dib K, Cherrah Y, Rida S, Filali-Maltouf A, Ennibi O. | Evid Based Complement Alternat Med | 10.1155/2021/8351332 | 2021 | | |
| Propolis in Dental Implantology: A Systematic Review of Its Effects and Benefits. | Sycinska-Dziarnowska M, Szyszka-Sommerfeld L, Ziabka M, Wozniak K, Spagnuolo G. | J Funct Biomater | 10.3390/jfb15110339 | 2024 | | |
| Susceptibility of periodontal pathogens to a novel target-specific drug delivery system containing self-nanoemulsifying curcumin: An in vitro study. | Hr V, Daniel RA, Prabhu A, P S, Basavaraju S. | J Adv Periodontol Implant Dent | 10.34172/japid.2023.024 | 2023 | | |
| Real-time flow cytometry to assess qualitative and quantitative responses of oral pathobionts during exposure to antiseptics. | Chatzigiannidou I, Heyse J, Props R, Rubbens P, Mermans F, Teughels W, Van de Wiele T, Boon N. | Microbiol Spectr | 10.1128/spectrum.00955-24 | 2024 | | |
| Antibacterial Activity of Fusidic Acid-Loaded Electrospun Polylactide Fiber Fleeces Against Periodontopathogenic Species. | Sigusch BW, Reise M, Kranz S, Beck J, Wagner K, Guellmar A, Heyder M. | Pharmaceutics | 10.3390/pharmaceutics17070821 | 2025 | | |
| Antibacterial Activity of 2-Hydroxyisocaproic Acid (HICA) Against Obligate Anaerobic Bacterial Species Associated With Periodontal Disease. | Sakko M, Rautemaa-Richardson R, Sakko S, Richardson M, Sorsa T. | Microbiol Insights | 10.1177/11786361211050086 | 2021 | | |
| Comparison of the antimicrobial reduction effect of photodynamic inactivation with the addition of chlorophyll and curcumin photosensitizer in Aggregatibacter actinomycetemcomitans and Enterococcus faecalis. | Arifianto D, Astuti SD, Medyaz SR, Lestari SB, Samian S, Nurdin DZI, Hariyani DA, Susilo Y, Syahrom A. | F1000Res | 10.12688/f1000research.128483.5 | 2023 | | |
| Inhibition of Sphingosine-1-Phosphate Receptor 2 by JTE013 Enhanced Alveolar Bone Regeneration by Promoting Angiogenesis. | Lory W, Wellslager B, Sun C, Yilmaz O, Yu H. | Int J Mol Sci | 10.3390/ijms24043401 | 2023 | | |
| Thermoplastic Zinc-Infused Polymer for Chairside Socket Seal Abutments Enhances Antimicrobial and Tissue-Integrative Properties. | Van Holm W, Vandamme K, Hadisurya J, Pamuk F, Zayed N, Aktan MK, Braem A, Temmerman A, Teughels W. | Antibiotics (Basel) | 10.3390/antibiotics14050441 | 2025 | | |
| Pathogenicity | In vitro investigation of the antibacterial and anti-inflammatory effects of LED irradiation. | Lee J, Song HY, Ahn SH, Song W, Seol YJ, Lee YM, Koo KT. | J Periodontal Implant Sci | 10.5051/jpis.2200920046 | 2023 | |
| Pathogenicity | Anti-Inflammatory and Osteogenic Effect of Phloroglucinol-Enriched Whey Protein Isolate Fibrillar Coating on Ti-6Al-4V Alloy. | Mieszkowska A, Martocq L, Koptyug A, Surmeneva MA, Surmenev RA, Naderi J, Muchova M, Gurzawska-Comis KA, Douglas TEL, Douglas TEL. | Polymers (Basel) | 10.3390/polym17111514 | 2025 | |
| Electrospun Azithromycin-Laden Gelatin Methacryloyl Fibers for Endodontic Infection Control. | Ayoub AA, Mahmoud AH, Ribeiro JS, Daghrery A, Xu J, Fenno JC, Schwendeman A, Sasaki H, Dal-Fabbro R, Bottino MC. | Int J Mol Sci | 10.3390/ijms232213761 | 2022 | | |
| An in vitro model for studies of attenuation of antibiotic-inhibited growth of Aggregatibacter actinomycetemcomitans Y4 by polyamines. | Wattimena A, Ganesan SM, Kumar PS, Dabdoub SM, Walters JD. | Mol Oral Microbiol | 10.1111/omi.12353 | 2021 | | |
| JP2 Genotype of Aggregatibacter actinomycetemcomitans in Caucasian Patients: A Presentation of Two Cases. | Stahli A, Sculean A, Eick S. | Pathogens | 10.3390/pathogens9030178 | 2020 | | |
| Association between periodontal bacteria and degenerative aortic stenosis: a pilot study. | Kataoka A, Katagiri S, Kawashima H, Nagura F, Nara Y, Hioki H, Nakashima M, Sasaki N, Hatasa M, Maekawa S, Ohsugi Y, Shiba T, Watanabe Y, Shimokawa T, Iwata T, Kozuma K. | J Periodontal Implant Sci | 10.5051/jpis.2006040302 | 2021 | | |
| Antibodies to oral pathobionts and colon cancer risk in the CLUE I cohort study. | Debertin J, Teles F, Martin LM, Lu J, Koestler DC, Kelsey KT, Beck JD, Platz EA, Michaud DS. | Int J Cancer | 10.1002/ijc.34527 | 2023 | | |
| Oral Lactobacillus species and their probiotic capabilities in patients with periodontitis and periodontally healthy individuals. | Etebarian A, Sheshpari T, Kabir K, Sadeghi H, Moradi A, Hafedi A. | Clin Exp Dent Res | 10.1002/cre2.740 | 2023 | | |
| Pathogenicity | The Subgingival Plaque Microbiome, Systemic Antibodies Against Bacteria and Citrullinated Proteins Following Periodontal Therapy. | Davison E, Johnston W, Piela K, Rosier BT, Paterson M, Mira A, Culshaw S. | Pathogens | 10.3390/pathogens10020193 | 2021 | |
| Streptococcus salivarius inhibits immune activation by periodontal disease pathogens. | MacDonald KW, Chanyi RM, Macklaim JM, Cadieux PA, Reid G, Burton JP. | BMC Oral Health | 10.1186/s12903-021-01606-z | 2021 | | |
| An Antibacterial Strategy of Mg-Cu Bone Grafting in Infection-Mediated Periodontics. | Zhao X, Wan P, Wang H, Zhang S, Liu J, Chang C, Yang K, Pan Y. | Biomed Res Int | 10.1155/2020/7289208 | 2020 | | |
| Putative periodontopathic bacteria and herpes viruses interactions in the subgingival plaque of patients with aggressive periodontitis and healthy controls. | Elamin A, Ali RW, Bakken V. | Clin Exp Dent Res | 10.1002/cre2.80 | 2017 | | |
| Phylogeny | Quantifying synthetic bacterial community composition with flow cytometry: efficacy in mock communities and challenges in co-cultures. | Mermans F, Chatzigiannidou I, Teughels W, Boon N. | mSystems | 10.1128/msystems.01009-24 | 2025 | |
| Characterization of Aggregatibacter actinomycetemcomitans Serotype b Strains with Five Different, Including Two Novel, Leukotoxin Promoter Structures. | Claesson R, Chiang HM, Lindholm M, Hoglund Aberg C, Haubek D, Johansson A, Johansson A, Oscarsson J. | Vaccines (Basel) | 10.3390/vaccines8030398 | 2020 | | |
| Succession of oral bacterial colonizers on dental implant materials: An in vitro biofilm model. | Siddiqui DA, Fidai AB, Natarajan SG, Rodrigues DC. | Dent Mater | 10.1016/j.dental.2021.12.021 | 2022 | | |
| Metabolism | Humoral immune response to heat shock protein 60 of Aggregatibacter actinomycetemcomitans and cross-reactivity with malondialdehyde acetaldehyde-modified LDL. | Kyrklund M, Bildo M, Akhi R, Nissinen AE, Pussinen P, Horkko S, Wang C. | PLoS One | 10.1371/journal.pone.0230682 | 2020 | |
| COMPARISON OF ANTI BACTERIAL EFFICACY OF PHOTODYNAMIC THERAPY AND DOXYCYCLINE ON AGGREGATIBACTER ACTINOMYCETEMCOMITANS. | Setiawatie EM, Lestari VP, Astuti SD. | Afr J Infect Dis | 10.2101/ajid.12v1s.14 | 2018 | | |
| Chemical Composition, Antimicrobial activity, in Vitro Cytotoxicity and Leukotoxin Neutralization of Essential Oil from Origanum vulgare against Aggregatibacter actinomycetemcomitans. | Akkaoui S, Johansson A, Johansson A, Yagoubi M, Haubek D, El Hamidi A, Rida S, Claesson R, Ennibi O. | Pathogens | 10.3390/pathogens9030192 | 2020 | | |
| Pathogenicity | Aggregatibacter actinomycetemcomitans LPS binds human interleukin-8. | Ahlstrand T, Kovesjoki L, Maula T, Oscarsson J, Ihalin R. | J Oral Microbiol | 10.1080/20002297.2018.1549931 | 2019 | |
| Machine learning enabled multiplex detection of periodontal pathogens by surface-enhanced Raman spectroscopy. | Rathnayake RAC, Zhao Z, McLaughlin N, Li W, Yan Y, Chen LL, Xie Q, Wu CD, Mathew MT, Wang RR. | Int J Biol Macromol | 10.1016/j.ijbiomac.2023.128773 | 2024 | | |
| Metabolism | In vitro Increased Respiratory Activity of Selected Oral Bacteria May Explain Competitive and Collaborative Interactions in the Oral Microbiome. | Hernandez-Sanabria E, Slomka V, Herrero ER, Kerckhof FM, Zaidel L, Teughels W, Boon N. | Front Cell Infect Microbiol | 10.3389/fcimb.2017.00235 | 2017 | |
| Thermoresponsive Azithromycin-Loaded Niosome Gel Based on Poloxamer 407 and Hyaluronic Interactions for Periodontitis Treatment. | Kerdmanee K, Phaechamud T, Limsitthichaikoon S. | Pharmaceutics | 10.3390/pharmaceutics14102032 | 2022 | | |
| The Proteome of Community Living Candida albicans Is Differentially Modulated by the Morphologic and Structural Features of the Bacterial Cohabitants. | Truong T, Pang LM, Rajan S, Wong SSW, Fung YME, Samaranayake L, Seneviratne CJ. | Microorganisms | 10.3390/microorganisms8101541 | 2020 | | |
| O-Polysaccharide Plays a Major Role on the Virulence and Immunostimulatory Potential of Aggregatibacter actinomycetemcomitans During Periodontal Infection. | Monasterio G, Castillo F, Astorga J, Hoare A, Terraza-Aguirre C, Cafferata EA, Villablanca EJ, Vernal R. | Front Immunol | 10.3389/fimmu.2020.591240 | 2020 | | |
| In Vitro Evaluation of Structural Factors Favouring Bacterial Adhesion on Orthodontic Adhesive Resins. | Condo R, Mampieri G, Pasquantonio G, Giancotti A, Pirelli P, Cataldi ME, La Rocca S, Leggeri A, Notargiacomo A, Maiolo L, De Filippis P, Cerroni L. | Materials (Basel) | 10.3390/ma14102485 | 2021 | | |
| Circulating IgG antibodies to periodontal bacteria and lung cancer risk in the CLUE cohorts. | Ampomah NK, Teles F, Martin LM, Lu J, Koestler DC, Kelsey KT, Beck JD, Platz EA, Michaud DS. | JNCI Cancer Spectr | 10.1093/jncics/pkad029 | 2023 | | |
| Mouthwash Effects on LGG-Integrated Experimental Oral Biofilms. | Jiang Q, Kainulainen V, Stamatova I, Janket SJ, Meurman JH, Korpela R. | Dent J (Basel) | 10.3390/dj8030096 | 2020 | | |
| Association among serum and salivary A. actinomycetemcomitans specific immunoglobulin antibodies and periodontitis. | Isola G, Polizzi A, Patini R, Ferlito S, Alibrandi A, Palazzo G. | BMC Oral Health | 10.1186/s12903-020-01258-5 | 2020 | | |
| Spatial Distribution and Chemical Tolerance of Streptococcus mutans within Dual-Species Cariogenic Biofilms. | Nakanishi Y, Yamamoto T, Obana N, Toyofuku M, Nomura N, Kaneko A. | Microbes Environ | 10.1264/jsme2.me18113 | 2018 | | |
| Enzymology | Antibacterial, Antibiofilm and Anti-Inflammatory Activities of Eugenol Clove Essential Oil against Resistant Helicobacter pylori. | Elbestawy MKM, El-Sherbiny GM, Moghannem SA. | Molecules | 10.3390/molecules28062448 | 2023 | |
| Metabolism | Periodontal pathogenic bacteria, Aggregatibacter actinomycetemcomitans affect non-alcoholic fatty liver disease by altering gut microbiota and glucose metabolism. | Komazaki R, Katagiri S, Takahashi H, Maekawa S, Shiba T, Takeuchi Y, Kitajima Y, Ohtsu A, Udagawa S, Sasaki N, Watanabe K, Sato N, Miyasaka N, Eguchi Y, Anzai K, Izumi Y. | Sci Rep | 10.1038/s41598-017-14260-9 | 2017 | |
| Detection of antimicrobial activity of banana peel (Musa paradisiaca L.) on Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans: An in vitro study. | Kapadia SP, Pudakalkatti PS, Shivanaikar S. | Contemp Clin Dent | 10.4103/0976-237x.169864 | 2015 | | |
| Can Our Blood Help Ensure Antimicrobial and Anti-Inflammatory Properties in Oral and Maxillofacial Surgery? | Micko L, Salma I, Skadins I, Egle K, Salms G, Dubnika A. | Int J Mol Sci | 10.3390/ijms24021073 | 2023 | | |
| Safe-by-Design Antibacterial Peroxide-Substituted Biomimetic Apatites: Proof of Concept in Tropical Dentistry. | Ana ID, Lestari A, Lagarrigue P, Soulie J, Anggraeni R, Maube-Bosc F, Thouron C, Duployer B, Tenailleau C, Drouet C. | J Funct Biomater | 10.3390/jfb13030144 | 2022 | | |
| Multiplex real-time PCR detection and relative quantification of periodontal pathogens. | Coffey J, Choudhry M, Shlossman M, Makin IRS, Singh VK. | Clin Exp Dent Res | 10.1002/cre2.37 | 2016 | | |
| Pathogenicity | Growth Media Affect Assessment of Antimicrobial Activity of Plant-Derived Polyphenols. | Xu X, Ou ZM, Wu CD. | Biomed Res Int | 10.1155/2018/8308640 | 2018 | |
| Traditionally used herbal medicines with antibacterial effect on Aggegatibacter actinomycetemcomitans: Boswellia serrata and Nigella sativa. | Maraghehpour B, Khayamzadeh M, Najafi S, Kharazifard M. | J Indian Soc Periodontol | 10.4103/jisp.jisp_12_17 | 2016 | | |
| Pathogenicity | Antimicrobial activity of NO-releasing compounds against periodontal pathogens. | Shim JS, Park DS, Baek DH, Jha N, Park SI, Yun HJ, Kim WJ, Ryu JJ. | PLoS One | 10.1371/journal.pone.0199998 | 2018 | |
| Localization and density of Porphyromonas gingivalis and Tannerella forsythia in gingival and subgingival granulation tissues affected by chronic or aggressive periodontitis. | Rajakaruna GA, Negi M, Uchida K, Sekine M, Furukawa A, Ito T, Kobayashi D, Suzuki Y, Akashi T, Umeda M, Meinzer W, Izumi Y, Eishi Y. | Sci Rep | 10.1038/s41598-018-27766-7 | 2018 | | |
| Pathogenicity | A novel chlorhexidine-hexametaphosphate coating for titanium with antibiofilm efficacy and stem cell cytocompatibility. | Garner SJ, Dalby MJ, Nobbs AH, Barbour ME. | J Mater Sci Mater Med | 10.1007/s10856-021-06616-5 | 2021 | |
| In Vitro Antimicrobial and Antiproliferative Activity of Amphipterygium adstringens. | Rodriguez-Garcia A, Peixoto IT, Verde-Star MJ, De la Torre-Zavala S, Aviles-Arnaut H, Ruiz AL. | Evid Based Complement Alternat Med | 10.1155/2015/175497 | 2015 | | |
| Preparation and Evaluation of Metronidazole-Loaded Pectin Films for Potentially Targeting a Microbial Infection Associated with Periodontal Disease. | Junmahasathien T, Panraksa P, Protiarn P, Hormdee D, Noisombut R, Kantrong N, Jantrawut P. | Polymers (Basel) | 10.3390/polym10091021 | 2018 | | |
| Natural Compounds in the Battle against Microorganisms-Linalool. | Maczka W, Duda-Madej A, Grabarczyk M, Winska K. | Molecules | 10.3390/molecules27206928 | 2022 | | |
| Phylogeny | Optimal 16S rRNA gene amplicon sequencing analysis for oral microbiota to avoid the potential bias introduced by trimming length, primer, and database. | Nagai T, Shiba T, Komatsu K, Watanabe T, Nemoto T, Maekawa S, Kobayashi R, Matsumura S, Ohsugi Y, Katagiri S, Takeuchi Y, Iwata T. | Microbiol Spectr | 10.1128/spectrum.03512-23 | 2024 | |
| Serum lipopolysaccharide neutralizing capacity in ischemic stroke. | Leskela J, Pietiainen M, Safer A, Lehto M, Metso J, Malle E, Buggle F, Becher H, Sundvall J, Grau AJ, Pussinen PJ, Palm F. | PLoS One | 10.1371/journal.pone.0228806 | 2020 | | |
| Dysbiotic oral microbiota contributes to alveolar bone loss associated with obesity in mice. | Chaves IM, Zicker MC, Laranjeira AO, Silveira ALM, Aguiar DC, Barrioni BR, Ferreira AVM, Teixeira MM, Silva TAD, Souza DDG, Madeira MFM. | J Appl Oral Sci | 10.1590/1678-7757-2022-0238 | 2022 | | |
| Antimicrobial capacity of Leucocyte-and Platelet Rich Fibrin against periodontal pathogens. | Castro AB, Herrero ER, Slomka V, Pinto N, Teughels W, Quirynen M. | Sci Rep | 10.1038/s41598-019-44755-6 | 2019 | | |
| Association of periodontitis and oral microbiomes with Alzheimer's disease: A narrative systematic review. | Mao S, Huang CP, Lan H, Lau HG, Chiang CP, Chen YW. | J Dent Sci | 10.1016/j.jds.2022.07.001 | 2022 | | |
| Metabolism | Existence of natural mouse IgG mAbs recognising epitopes shared by malondialdehyde acetaldehyde adducts and Porphyromonas gingivalis. | Kyrklund M, Kaski H, Akhi R, Nissinen AE, Kummu O, Bergmann U, Pussinen P, Horkko S, Wang C. | Innate Immun | 10.1177/1753425920981133 | 2021 | |
| Metabolism | Sphingosine-1-Phosphate Receptor 2 Controls Podosome Components Induced by RANKL Affecting Osteoclastogenesis and Bone Resorption. | Hsu LC, Reddy SV, Yilmaz O, Yu H. | Cells | 10.3390/cells8010017 | 2019 | |
| Associations between Periodontal Microbiota and Death Rates. | Chiu CJ, Chang ML, Taylor A. | Sci Rep | 10.1038/srep35428 | 2016 | | |
| Comparative evaluation of the efficacy of a herbal mouthwash and chlorhexidine mouthwash on select periodontal pathogens: An in vitro and ex vivo study. | Pathan MM, Bhat KG, Joshi VM. | J Indian Soc Periodontol | 10.4103/jisp.jisp_382_16 | 2017 | | |
| Accuracy of commercial kits and published primer pairs for the detection of periodontopathogens. | Santigli E, Leitner E, Wimmer G, Kessler HH, Feierl G, Grube M, Eberhard K, Klug B. | Clin Oral Investig | 10.1007/s00784-016-1748-9 | 2016 | | |
| Antimicrobial and Anti-inflammatory Lingonberry Mouthwash - A Clinical Pilot Study in the Oral Cavity. | Parnanen P, Nikula-Ijas P, Sorsa T. | Microorganisms | 10.3390/microorganisms7090331 | 2019 | | |
| Enzymology | Changes in salivary periodontal pathogens after orthodontic treatment: An in vivo prospective study. | Kim K, Jung WS, Cho S, Ahn SJ. | Angle Orthod | 10.2319/070615-450.1 | 2016 | |
| Antimicrobial Mechanisms of Leucocyte- and Platelet Rich Fibrin Exudate Against Planktonic Porphyromonas gingivalis and Within Multi-Species Biofilm: A Pilot Study. | Rodriguez Sanchez F, Verspecht T, Castro AB, Pauwels M, Andres CR, Quirynen M, Teughels W. | Front Cell Infect Microbiol | 10.3389/fcimb.2021.722499 | 2021 | | |
| Probiotics for periodontal health-Current molecular findings. | Nguyen T, Brody H, Radaic A, Kapila Y. | Periodontol 2000 | 10.1111/prd.12382 | 2021 | | |
| Pathogenicity | Photocatalytical Antibacterial Activity of Mixed-Phase TiO2 Nanocomposite Thin Films against Aggregatibacter actinomycetemcomitans. | Yeniyol S, Mutlu I, He Z, Yuksel B, Boylan RJ, Urgen M, Karabuda ZC, Basegmez C, Ricci JL. | Biomed Res Int | 10.1155/2015/705871 | 2015 | |
| Metabolism | NADPH Oxidase Contributes to Resistance against Aggregatibacter actinomycetemcomitans-Induced Periodontitis in Mice. | Bast A, Kubis H, Holtfreter B, Ribback S, Martin H, Schreiner HC, Dominik MJ, Breitbach K, Dombrowski F, Kocher T, Steinmetz I. | Infect Immun | 10.1128/iai.00849-16 | 2017 | |
| Ozone application as adjunctive therapy in chronic periodontitis: Clinical, microbiological and biochemical aspects. | Uraz A, Karaduman B, Isler SC, Gonen S, Cetiner D. | J Dent Sci | 10.1016/j.jds.2018.06.005 | 2019 | | |
| A Viability Quantitative PCR Dilemma: Are Longer Amplicons Better? | Van Holm W, Ghesquiere J, Boon N, Verspecht T, Bernaerts K, Zayed N, Chatzigiannidou I, Teughels W. | Appl Environ Microbiol | 10.1128/aem.02653-20 | 2021 | | |
| Mode of killing determines the necrotrophic response of oral bacteria. | Zayed N, Figueiredo J, Van Holm W, Boon N, Bernaerts K, Teughels W. | J Oral Microbiol | 10.1080/20002297.2023.2184930 | 2023 | | |
| Distribution of biotypes and leukotoxic activity of Aggregatibacter actinomycetemcomitans isolated from Brazilian patients with chronic periodontitis. | Gaetti-Jardim E, Wahasugui TC, Tomazinho PH, Marques MM, Nakano V, Avila-Campos MJ. | Braz J Microbiol | 10.1590/s1517-838220080004000011 | 2008 | | |
| Interactions between Lactobacillus rhamnosus GG and oral micro-organisms in an in vitro biofilm model. | Jiang Q, Stamatova I, Kainulainen V, Korpela R, Meurman JH. | BMC Microbiol | 10.1186/s12866-016-0759-7 | 2016 | | |
| Antimicrobial potential of known and novel probiotics on in vitro periodontitis biofilms. | Van Holm W, Carvalho R, Delanghe L, Eilers T, Zayed N, Mermans F, Bernaerts K, Boon N, Claes I, Lebeer S, Teughels W. | NPJ Biofilms Microbiomes | 10.1038/s41522-023-00370-y | 2023 | | |
| Evaluation of chemical composition and efficacy of Chinese propolis extract on Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans: An in vitro study. | Agarwal G, Vemanaradhya GG, Mehta DS. | Contemp Clin Dent | 10.4103/0976-237x.103614 | 2012 | | |
| Metabolism | Quantitative discrimination of Aggregatibacter actinomycetemcomitans highly leukotoxic JP2 clone from non-JP2 clones in diagnosis of aggressive periodontitis. | Yoshida A, Ennibi OK, Miyazaki H, Hoshino T, Hayashida H, Nishihara T, Awano S, Ansai T. | BMC Infect Dis | 10.1186/1471-2334-12-253 | 2012 | |
| Metabolism | FTY720 inhibited proinflammatory cytokine release and osteoclastogenesis induced by Aggregatibacter actinomycetemcomitans. | Yu H, Herbert BA, Valerio M, Yarborough L, Hsu LC, Argraves KM. | Lipids Health Dis | 10.1186/s12944-015-0057-7 | 2015 | |
| Pathogenicity | Azithromycin kills invasive Aggregatibacter actinomycetemcomitans in gingival epithelial cells. | Lai PC, Walters JD. | Antimicrob Agents Chemother | 10.1128/aac.02558-12 | 2013 | |
| Effect of flavonoids on antimicrobial activity of microorganisms present in dental plaque. | Gutierrez-Venegas G, Gomez-Mora JA, Meraz-Rodriguez MA, Flores-Sanchez MA, Ortiz-Miranda LF. | Heliyon | 10.1016/j.heliyon.2019.e03013 | 2019 | | |
| Genome-wide association study of periodontal pathogen colonization. | Divaris K, Monda KL, North KE, Olshan AF, Lange EM, Moss K, Barros SP, Beck JD, Offenbacher S. | J Dent Res | 10.1177/0022034512447951 | 2012 | | |
| Inverse Association of Plasma IgG Antibody to Aggregatibacter actinomycetemcomitans and High C-Reactive Protein Levels in Patients with Metabolic Syndrome and Periodontitis. | Thanakun S, Pornprasertsuk-Damrongsri S, Gokyu M, Kobayashi H, Izumi Y. | PLoS One | 10.1371/journal.pone.0148638 | 2016 | | |
| Metabolism | Diverse Toll-like receptors mediate cytokine production by Fusobacterium nucleatum and Aggregatibacter actinomycetemcomitans in macrophages. | Park SR, Kim DJ, Han SH, Kang MJ, Lee JY, Jeong YJ, Lee SJ, Kim TH, Ahn SG, Yoon JH, Park JH. | Infect Immun | 10.1128/iai.01226-13 | 2014 | |
| Pathogenicity | Nanoparticle-encapsulated chlorhexidine against oral bacterial biofilms. | Seneviratne CJ, Leung KC, Wong CH, Lee SF, Li X, Leung PC, Lau CB, Wat E, Jin L. | PLoS One | 10.1371/journal.pone.0103234 | 2014 | |
| Enzymology | In Vitro Effect of Porphyromonas gingivalis Methionine Gamma Lyase on Biofilm Composition and Oral Inflammatory Response. | Stephen AS, Millhouse E, Sherry L, Aduse-Opoku J, Culshaw S, Ramage G, Bradshaw DJ, Burnett GR, Allaker RP. | PLoS One | 10.1371/journal.pone.0169157 | 2016 | |
| Pathogenicity | The epithelial cell response to health and disease associated oral biofilm models. | Ramage G, Lappin DF, Millhouse E, Malcolm J, Jose A, Yang J, Bradshaw DJ, Pratten JR, Culshaw S. | J Periodontal Res | 10.1111/jre.12395 | 2017 | |
| Metabolism | Dysbiosis by neutralizing commensal mediated inhibition of pathobionts. | Herrero ER, Slomka V, Boon N, Bernaerts K, Hernandez-Sanabria E, Quirynen M, Teughels W. | Sci Rep | 10.1038/srep38179 | 2016 | |
| Periodontal Bacteria and Prediabetes Prevalence in ORIGINS: The Oral Infections, Glucose Intolerance, and Insulin Resistance Study. | Demmer RT, Jacobs DR, Singh R, Zuk A, Rosenbaum M, Papapanou PN, Desvarieux M. | J Dent Res | 10.1177/0022034515590369 | 2015 | | |
| Biofilm-stimulated epithelium modulates the inflammatory responses in co-cultured immune cells. | Brown JL, Johnston W, Delaney C, Rajendran R, Butcher J, Khan S, Bradshaw D, Ramage G, Culshaw S. | Sci Rep | 10.1038/s41598-019-52115-7 | 2019 | | |
| Periodontal inflammation and alveolar bone loss induced by Aggregatibacter actinomycetemcomitans is attenuated in sphingosine kinase 1-deficient mice. | Yu H, Sun C, Argraves KM. | J Periodontal Res | 10.1111/jre.12276 | 2016 | | |
| Pathogenicity | Oral biofilms exposure to chlorhexidine results in altered microbial composition and metabolic profile. | Chatzigiannidou I, Teughels W, Van de Wiele T, Boon N. | NPJ Biofilms Microbiomes | 10.1038/s41522-020-0124-3 | 2020 | |
| Metabolism | Sphingosine-1-Phosphate Receptor 2 Regulates Proinflammatory Cytokine Production and Osteoclastogenesis. | Yu H. | PLoS One | 10.1371/journal.pone.0156303 | 2016 | |
| Relevance of Topographic Parameters on the Adhesion and Proliferation of Human Gingival Fibroblasts and Oral Bacterial Strains. | Pacha-Olivenza MA, Tejero R, Fernandez-Calderon MC, Anitua E, Troya M, Gonzalez-Martin ML. | Biomed Res Int | 10.1155/2019/8456342 | 2019 | | |
| Metabolism | Lifestyle, dietary factors, and antibody levels to oral bacteria in cancer-free participants of a European cohort study. | Michaud DS, Izard J, Rubin Z, Johansson I, Weiderpass E, Tjonneland A, Olsen A, Overvad K, Boutron-Ruault MC, Clavel-Chapelon F, Dossus L, Kaaks R, Katzke VA, Boeing H, Foerster J, Trichopoulou A, Naska A, Ziara G, Vineis P, Grioni S, Palli D, Tumino R, Mattiello A, Peeters PH, Siersema PD, Barricarte A, Huerta JM, Molina-Montes E, Dorronsoro M, Quiros JR, Duell EJ, Ohlsson B, Jeppsson B, Johansson A, Lif P, Khaw KT, Wareham N, Travis RC, Key TJ, Freisling H, Duarte-Salles T, Stepien M, Riboli E, Bueno-de-Mesquita HB. | Cancer Causes Control | 10.1007/s10552-013-0265-2 | 2013 | |
| Modulation of Neutrophil Extracellular Trap and Reactive Oxygen Species Release by Periodontal Bacteria. | Hirschfeld J, White PC, Milward MR, Cooper PR, Chapple ILC. | Infect Immun | 10.1128/iai.00297-17 | 2017 | | |
| Development of antiseptic adaptation and cross-adapatation in selected oral pathogens in vitro. | Verspecht T, Rodriguez Herrero E, Khodaparast L, Khodaparast L, Boon N, Bernaerts K, Quirynen M, Teughels W. | Sci Rep | 10.1038/s41598-019-44822-y | 2019 | | |
| Pathogenicity | In vitro-activity of oily calcium hydroxide suspension on microorganisms as well as on human alveolar osteoblasts and periodontal ligament fibroblasts. | Eick S, Strugar T, Miron RJ, Sculean A. | BMC Oral Health | 10.1186/1472-6831-14-9 | 2014 | |
| Metabolism | Clarithromycin accumulation by phagocytes and its effect on killing of Aggregatibacter actinomycetemcomitans. | Iskandar I, Walters JD. | J Periodontol | 10.1902/jop.2010.100221 | 2011 | |
| Expression of receptor activator of nuclear factor-kappaB ligand by B cells in response to oral bacteria. | Han X, Lin X, Seliger AR, Eastcott J, Kawai T, Taubman MA. | Oral Microbiol Immunol | 10.1111/j.1399-302x.2008.00494.x | 2009 | | |
| Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface. | Calatayud Arroyo M, Van de Wiele T, Hernandez-Sanabria E. | J Vis Exp | 10.3791/57699 | 2018 | | |
| Plasma antibodies to oral bacteria and risk of pancreatic cancer in a large European prospective cohort study. | Michaud DS, Izard J, Wilhelm-Benartzi CS, You DH, Grote VA, Tjonneland A, Dahm CC, Overvad K, Jenab M, Fedirko V, Boutron-Ruault MC, Clavel-Chapelon F, Racine A, Kaaks R, Boeing H, Foerster J, Trichopoulou A, Lagiou P, Trichopoulos D, Sacerdote C, Sieri S, Palli D, Tumino R, Panico S, Siersema PD, Peeters PH, Lund E, Barricarte A, Huerta JM, Molina-Montes E, Dorronsoro M, Quiros JR, Duell EJ, Ye W, Sund M, Lindkvist B, Johansen D, Khaw KT, Wareham N, Travis RC, Vineis P, Bueno-de-Mesquita HB, Riboli E. | Gut | 10.1136/gutjnl-2012-303006 | 2013 | | |
| Antimicrobial Activity of Chemokine CXCL10 for Dermal and Oral Microorganisms. | Holdren GO, Rosenthal DJ, Yang J, Bates AM, Fischer CL, Zhang Y, Brogden NK, Brogden KA. | Antibiotics (Basel) | 10.3390/antibiotics3040527 | 2014 | | |
| Metabolism | Molecular genotyping of isolates of Actinobacillus actinomycetemcomitans by pulsed-field gel electrophoresis after separate digestion with Sse8387I and XhoI. | Matsuda M, Takayama K, Haga S, Kagawa S, Ohta H, Fukui K, Moore JE. | J Basic Microbiol | 10.1002/1521-4028(200205)42:2<137::aid-jobm137>3.0.co;2-8 | 2002 | |
| Enzymology | Association of three bacterial species and periodontal status in Chinese adults: an epidemiological approach. | Deng T, Wang L, Lv J, Pang J, Liu B, Du Y, Ke J. | J Clin Microbiol | 10.1128/jcm.01819-10 | 2011 | |
| Metabolism | Oral Microbiota Display Profound Differential Metabolic Kinetics and Community Shifts upon Incubation with Sucrose, Trehalose, Kojibiose, and Xylitol. | Onyango SO, De Clercq N, Beerens K, Van Camp J, Desmet T, Van de Wiele T. | Appl Environ Microbiol | 10.1128/aem.01170-20 | 2020 | |
| Development of an in vitro periodontal biofilm model for assessing antimicrobial and host modulatory effects of bioactive molecules. | Millhouse E, Jose A, Sherry L, Lappin DF, Patel N, Middleton AM, Pratten J, Culshaw S, Ramage G. | BMC Oral Health | 10.1186/1472-6831-14-80 | 2014 | | |
| Clinical and microbiological effects of Lactobacillus reuteri probiotics in the treatment of chronic periodontitis: a randomized placebo-controlled study. | Teughels W, Durukan A, Ozcelik O, Pauwels M, Quirynen M, Haytac MC. | J Clin Periodontol | 10.1111/jcpe.12155 | 2013 | | |
| Comparison of the modulatory effects of three structurally similar potential prebiotic substrates on an in vitro multi-species oral biofilm. | Verspecht T, Van Holm W, Boon N, Bernaerts K, Daep CA, Zayed N, Quirynen M, Teughels W. | Sci Rep | 10.1038/s41598-021-94510-z | 2021 | | |
| Antibacterial Activity of As-Annealed TiO2 Nanotubes Doped with Ag Nanoparticles against Periodontal Pathogens. | Yeniyol S, He Z, Yuksel B, Boylan RJ, Urgen M, Ozdemir T, Ricci JL. | Bioinorg Chem Appl | 10.1155/2014/829496 | 2014 | | |
| The vaginal microflora in relation to gingivitis. | Persson R, Hitti J, Verhelst R, Vaneechoutte M, Persson R, Hirschi R, Weibel M, Rothen M, Temmerman M, Paul K, Eschenbach D. | BMC Infect Dis | 10.1186/1471-2334-9-6 | 2009 | | |
| Proteolytic Activities of Oral Bacteria on ProMMP-9 and the Effect of Synthetic Proteinase Inhibitors. | Jie Bao G, Kari K, Tervahartiala T, Sorsa T, Meurman JH. | Open Dent J | 10.2174/1874210600802010096 | 2008 | | |
| Metabolism | Granulocyte elastase activity and PGE2 levels in gingival crevicular fluid in relation to the presence of subgingival periodontopathogens in subjects with untreated adult periodontitis. | Jin LJ, Soder PO, Leung WK, Leung WK, Leung WK, Corbet EF, Corbet EF, Samaranayake LP, Soder B, Davies WI. | J Clin Periodontol | 10.1034/j.1600-051x.1999.260807.x | 1999 | |
| Repurposing AM404 for the treatment of oral infections by Porphyromonas gingivalis. | Gerits E, Spincemaille P, De Cremer K, De Brucker K, Beullens S, Thevissen K, Cammue BPA, Vandamme K, Fauvart M, Verstraeten N, Michiels J. | Clin Exp Dent Res | 10.1002/cre2.65 | 2017 | | |
| Metabolism | Vesicle-independent extracellular release of a proinflammatory outer membrane lipoprotein in free-soluble form. | Karched M, Ihalin R, Eneslatt K, Zhong D, Oscarsson J, Wai SN, Chen C, Asikainen SE. | BMC Microbiol | 10.1186/1471-2180-8-18 | 2008 | |
| Enzymology | Periodontal microbiota and phospholipases: the Oral Infections and Vascular Disease Epidemiology Study (INVEST). | Boillot A, Demmer RT, Mallat Z, Sacco RL, Jacobs DR, Benessiano J, Tedgui A, Rundek T, Papapanou PN, Desvarieux M. | Atherosclerosis | 10.1016/j.atherosclerosis.2015.07.039 | 2015 | |
| Pathogenicity | Beneficial effects of adiponectin on periodontal ligament cells under normal and regenerative conditions. | Nokhbehsaim M, Keser S, Nogueira AV, Cirelli JA, Jepsen S, Jager A, Eick S, Deschner J. | J Diabetes Res | 10.1155/2014/796565 | 2014 | |
| Enzymology | Development of species-specific primers for detection of Streptococcus mutans in mixed bacterial samples. | Chen Z, Saxena D, Caufield PW, Ge Y, Wang M, Li Y. | FEMS Microbiol Lett | 10.1111/j.1574-6968.2007.00756.x | 2007 | |
| Enzymology | Screening of Probiotic Candidates in Human Oral Bacteria for the Prevention of Dental Disease. | Terai T, Okumura T, Imai S, Nakao M, Yamaji K, Ito M, Nagata T, Kaneko K, Miyazaki K, Okada A, Nomura Y, Hanada N. | PLoS One | 10.1371/journal.pone.0128657 | 2015 | |
| Phylogeny | Are putative periodontal pathogens reliable diagnostic markers? | Riep B, Edesi-Neuss L, Claessen F, Skarabis H, Ehmke B, Flemmig TF, Bernimoulin JP, Gobel UB, Moter A. | J Clin Microbiol | 10.1128/jcm.01387-08 | 2009 | |
| Three-Dimensional In Vitro Oral Mucosa Models of Fungal and Bacterial Infections. | Tabatabaei F, Moharamzadeh K, Tayebi L. | Tissue Eng Part B Rev | 10.1089/ten.teb.2020.0016 | 2020 | | |
| Pathogenicity | Changes in clinical and microbiological periodontal profiles relate to progression of carotid intima-media thickness: the Oral Infections and Vascular Disease Epidemiology study. | Desvarieux M, Demmer RT, Jacobs DR, Papapanou PN, Sacco RL, Rundek T. | J Am Heart Assoc | 10.1161/jaha.113.000254 | 2013 | |
| Nutraceuticals in Periodontal Health: A Systematic Review on the Role of Vitamins in Periodontal Health Maintenance. | Varela-Lopez A, Navarro-Hortal MD, Giampieri F, Bullon P, Battino M, Quiles JL. | Molecules | 10.3390/molecules23051226 | 2018 | | |
| Metabolism | Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and alpha-enolase: implications for autoimmunity in rheumatoid arthritis. | Wegner N, Wait R, Sroka A, Eick S, Nguyen KA, Lundberg K, Kinloch A, Culshaw S, Potempa J, Venables PJ. | Arthritis Rheum | 10.1002/art.27552 | 2010 | |
| Multiserotype enzyme-linked immunosorbent assay as a diagnostic aid for periodontitis in large-scale studies. | Pussinen PJ, Vilkuna-Rautiainen T, Alfthan G, Mattila K, Asikainen S. | J Clin Microbiol | 10.1128/jcm.40.2.512-518.2002 | 2002 | | |
| Metabolism | Subgingival bacterial colonization profiles correlate with gingival tissue gene expression. | Papapanou PN, Behle JH, Kebschull M, Celenti R, Wolf DL, Handfield M, Pavlidis P, Demmer RT. | BMC Microbiol | 10.1186/1471-2180-9-221 | 2009 | |
| Metabolism | Necrotrophic growth of periodontopathogens is a novel virulence factor in oral biofilms. | Rodriguez Herrero E, Boon N, Pauwels M, Bernaerts K, Slomka V, Quirynen M, Teughels W. | Sci Rep | 10.1038/s41598-017-01239-9 | 2017 | |
| Metabolism | Differential utilization of nuclear factor-kappaB signaling pathways for gingival epithelial cell responses to oral commensal and pathogenic bacteria. | Chung WO, Dale BA. | Oral Microbiol Immunol | 10.1111/j.1399-302x.2007.00398.x | 2008 | |
| Antimicrobial Blue Light versus Pathogenic Bacteria: Mechanism, Application in the Food Industry, Hurdle Technologies and Potential Resistance. | Hadi J, Wu S, Brightwell G. | Foods | 10.3390/foods9121895 | 2020 | | |
| Influence of anti-Actinobacillus actinomycetemcomitans Y4 (serotype b) lipopolysaccharide on severity of generalized early-onset periodontitis. | Califano JV, Gunsolley JC, Nakashima K, Schenkein HA, Wilson ME, Tew JG. | Infect Immun | 10.1128/iai.64.9.3908-3910.1996 | 1996 | | |
| Antigenically diverse reference strains and autologous strains of Actinobacillus actinomycetemcomitans are equally efficient antigens in enzyme-linked immunosorbent assay analysis. | Vilkuna-Rautiainen T, Pussinen PJ, Mattila K, Vesanen M, Ahman H, Dogan B, Asikainen S. | J Clin Microbiol | 10.1128/jcm.40.12.4640-4645.2002 | 2002 | | |
| Metabolism | Characterization of a periplasmic protein involved in iron utilization of Actinobacillus actinomycetemcomitans. | Willemsen PT, Vulto I, Boxem M, de Graaff J. | J Bacteriol | 10.1128/jb.179.15.4949-4952.1997 | 1997 | |
| Metabolism | Modulation of Wnt5a expression by periodontopathic bacteria. | Nanbara H, Wara-aswapati N, Nagasawa T, Yoshida Y, Yashiro R, Bando Y, Kobayashi H, Khongcharoensuk J, Hormdee D, Pitiphat W, Boch JA, Izumi Y. | PLoS One | 10.1371/journal.pone.0034434 | 2012 | |
| Metabolism | TNF-alpha and antibodies to periodontal bacteria discriminate between Alzheimer's disease patients and normal subjects. | Kamer AR, Craig RG, Pirraglia E, Dasanayake AP, Norman RG, Boylan RJ, Nehorayoff A, Glodzik L, Brys M, de Leon MJ. | J Neuroimmunol | 10.1016/j.jneuroim.2009.08.013 | 2009 | |
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| Improved multiplex PCR using conserved and species-specific 16S rRNA gene primers for simultaneous detection of Actinobacillus actinomycetemcomitans, Bacteroides forsythus, and Porphyromonas gingivalis. | Tran SD, Rudney JD. | J Clin Microbiol | 10.1128/jcm.37.11.3504-3508.1999 | 1999 | | |
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| Enzymology | Direct selection of IS903 transposon insertions by use of a broad-host-range vector: isolation of catalase-deficient mutants of Actinobacillus actinomycetemcomitans. | Thomson VJ, Bhattacharjee MK, Fine DH, Derbyshire KM, Figurski DH. | J Bacteriol | 10.1128/jb.181.23.7298-7307.1999 | 1999 | |
| Opsonic antibody activity against Actinobacillus actinomycetemcomitans in patients with rapidly progressive periodontitis. | Sjostrom K, Darveau R, Page R, Whitney C, Engel D. | Infect Immun | 10.1128/iai.60.11.4819-4825.1992 | 1992 | | |
| Phylogeny | Structural and genetic analyses of O polysaccharide from Actinobacillus actinomycetemcomitans serotype f. | Kaplan JB, Perry MB, MacLean LL, Furgang D, Wilson ME, Fine DH. | Infect Immun | 10.1128/iai.69.9.5375-5384.2001 | 2001 | |
| Enzymology | Comparison of various detection methods for periodontopathic bacteria: can culture be considered the primary reference standard? | Loesche WJ, Lopatin DE, Stoll J, van Poperin N, Hujoel PP. | J Clin Microbiol | 10.1128/jcm.30.2.418-426.1992 | 1992 | |
| Phylogeny | Immunoglobulin G subclass response of juvenile periodontitis subjects to principal outer membrane proteins of Actinobacillus actinomycetemcomitans. | Wilson ME, Hamilton RG. | Infect Immun | 10.1128/iai.63.3.1062-1069.1995 | 1995 | |
| Metabolism | The potent bone-resorbing mediator of Actinobacillus actinomycetemcomitans is homologous to the molecular chaperone GroEL. | Kirby AC, Meghji S, Nair SP, White P, Reddi K, Nishihara T, Nakashima K, Willis AC, Sim R, Wilson M. | J Clin Invest | 10.1172/jci118150 | 1995 | |
| Pathogenicity | Synergistic effects of LFchimera and antibiotic against planktonic and biofilm form of Aggregatibacter actinomycetemcomitans. | Lachica MRCT, Anutrakunchai C, Prajaneh S, Nazmi K, Bolscher JGM, Taweechaisupapong S | PLoS One | 10.1371/journal.pone.0217205 | 2019 | |
| Pathogenicity | Killing activity of LFchimera on periodontopathic bacteria and multispecies oral biofilm formation in vitro. | Ruangcharoen S, Suwannarong W, Lachica MRCT, Bolscher JGM, Nazmi K, Khunkitti W, Taweechaisupapong S | World J Microbiol Biotechnol | 10.1007/s11274-017-2334-2 | 2017 | |
| Pathogenicity | Antimicrobial effect of lemongrass oil against oral malodour micro-organisms and the pilot study of safety and efficacy of lemongrass mouthrinse on oral malodour. | Satthanakul P, Taweechaisupapong S, Paphangkorakit J, Pesee M, Timabut P, Khunkitti W | J Appl Microbiol | 10.1111/jam.12667 | 2014 | |
| Pathogenicity | Influence of different biomaterials on the viability of Aggregatibacter actinomycetemcomitans. | Kasaj A, Willershausen B, Junker R, Callaway A, Krahn U, Kraft B, Pietsch M | Arch Oral Biol | 10.1016/j.archoralbio.2011.02.013 | 2011 | |
| Metabolism | Differential epithelial cell response upon stimulation with the Aggregatibacter actinomycetemcomitans strains VT 1169, VT 1560 DAM(-) and ATCC 4318. | Eberhard J, Banasch T, Jepsen S, Dommisch H | Epigenetics | 10.4161/epi.5.8.13106 | 2010 | |
| Pathogenicity | Reduction of periodontal pathogens adhesion by antagonistic strains. | Van Hoogmoed CG, Geertsema-Doornbusch GI, Teughels W, Quirynen M, Busscher HJ, Van der Mei HC | Oral Microbiol Immunol | 10.1111/j.1399-302X.2007.00388.x | 2008 | |
| A simple viability-maintaining method produces homogenic cell suspensions of autoaggregating wild-type Actinobacillus actinomycetemcomitans. | Karched M, Paul-Satyaseela M, Asikainen S | J Microbiol Methods | 10.1016/j.mimet.2006.06.004 | 2006 | | |
| Pathogenicity | Effect of ciprofloxacin on killing of Actinobacillus actinomycetemcomitans by polymorphonuclear leukocytes. | Cacchillo DA, Walters JD | Antimicrob Agents Chemother | 10.1128/AAC.46.6.1980-1984.2002 | 2002 | |
| Pathogenicity | Influence of surface modifications to titanium on antibacterial activity in vitro. | Yoshinari M, Oda Y, Kato T, Okuda K | Biomaterials | 10.1016/s0142-9612(00)00392-6 | 2001 | |
| Pathogenicity | Influence of surface modifications to titanium on oral bacterial adhesion in vitro. | Yoshinari M, Oda Y, Kato T, Okuda K, Hirayama A | J Biomed Mater Res | 10.1002/1097-4636(200011)52:2<388::aid-jbm20>3.0.co;2-e | 2000 | |
| Pathogenicity | Novel apoptosis-inducing activity in Bacteroides forsythus: a comparative study with three serotypes of Actinobacillus actinomycetemcomitans. | Arakawa S, Nakajima T, Ishikura H, Ichinose S, Ishikawa I, Tsuchida N | Infect Immun | 10.1128/IAI.68.8.4611-4615.2000 | 2000 | |
| Phylogeny | Heterogeneity in the immune response to serotype b LPS of Actinobacillus actinomycetemcomitans in inbred strains of mice. | Kato T, Honma K, Yamanaka A, Miura T, Okuda K | FEMS Immunol Med Microbiol | 10.1111/j.1574-695X.2000.tb01458.x | 2000 | |
| Pathogenicity | Antigenic components of Actinobacillus actinomycetemcomitans lipopolysaccharide recognized by sera from patients with localized juvenile periodontitis. | Gu K, Bainbridge B, Darveau RP, Page RC | Oral Microbiol Immunol | 10.1111/j.1399-302x.1998.tb00726.x | 1998 | |
| Enzymology | Isolation and characterization of hemolytic genes from Actinobacillus actinomycetemcomitans. | Kato T, Kimizuka R, Okuda K | FEMS Microbiol Lett | 10.1111/j.1574-6968.1996.tb08483.x | 1996 | |
| Metabolism | Identification of an immunoglobulin Fc receptor of Actinobacillus actinomycetemcomitans. | Mintz KP, Fives-Taylor PM | Infect Immun | 10.1128/iai.62.10.4500-4505.1994 | 1994 | |
| Enzymology | Identification and analysis of the gap region in the 23S ribosomal RNA from Actinobacillus actinomycetemcomitans. | Haraszthy VI, Sunday GJ, Bobek LA, Motley TS, Preus H, Zambon JJ | J Dent Res | 10.1177/00220345920710090401 | 1992 | |
| Pathogenicity | Evidence that the serotype b antigenic determinant of Actinobacillus actinomycetemcomitans Y4 resides in the polysaccharide moiety of lipopolysaccharide. | Wilson ME, Schifferle RE | Infect Immun | 10.1128/iai.59.4.1544-1551.1991 | 1991 | |
| Metabolism | Differential effects of five Aggregatibacter actinomycetemcomitans strains on gingival epithelial cells. | Shimada T, Sugano N, Nishihara R, Suzuki K, Tanaka H, Ito K | Oral Microbiol Immunol | 10.1111/j.1399-302X.2008.00449.x | 2008 | |
| Phylogeny | Bacterial adhesion of Actinobacillus actinomycetemcomitans serotypes to titanium implants: SEM evaluation. A preliminary report. | Okte E, Sultan N, Dogan B, Asikainen S | J Periodontol | 10.1902/jop.1999.70.11.1376 | 1999 | |
| Enzymology | Cloning of the gene encoding the Actinobacillus actinomycetemcomitans serotype b OmpA-like outer membrane protein. | Komatsuzawa H, Kawai T, Wilson ME, Taubman MA, Sugai M, Suginaka H | Infect Immun | 10.1128/IAI.67.2.942-945.1999 | 1999 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive11754.20251217.10
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
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