Aggregatibacter actinomycetemcomitans DSM 11122 is a microaerophile human pathogen that was isolated from chest aspirate.
microaerophile human pathogen 16S sequence Bacteria| @ref 20215 |
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Last LPSN update
2026-02-09 11:20:39 |
| Domain Bacteria |
| Phylum Pseudomonadota |
| Class Gammaproteobacteria |
| Order Pasteurellales |
| Family Pasteurellaceae |
| Genus Aggregatibacter |
| Species Aggregatibacter actinomycetemcomitans |
| Full scientific name Aggregatibacter actinomycetemcomitans (Klinger 1912) Nørskov-Lauritsen and Kilian 2006 |
| Synonyms (3) |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 4214 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | Medium recipe at MediaDive  | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base | ||
| 4214 | BHI MEDIUM (DSMZ Medium 215) | Medium recipe at MediaDive | Name: BHI MEDIUM (DSMZ Medium 215) Composition: Brain heart infusion 37.0 g/l Distilled water |
| 4214 | Oxygen tolerancemicroaerophile |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68377 | 17634 ChEBI | D-glucose | + | builds acid from | from API NH |
| 68377 | 18257 ChEBI | ornithine | - | degradation | from API NH |
| 68377 | 17992 ChEBI | sucrose | - | builds acid from | from API NH |
| 68377 | 27897 ChEBI | tryptophan | - | energy source | from API NH |
| 68377 | 16199 ChEBI | urea | - | hydrolysis | from API NH |
| Cat1 | Cat2 | Cat3 | |
|---|---|---|---|
| #Host Body-Site | #Other | #Thoracic segment | |
| #Host Body Product | #Fluids | #Aspirate |
Global distribution of 16S sequence LC383929 (>99% sequence identity) for Aggregatibacter actinomycetemcomitans subclade from Microbeatlas 
 Aquatic Samples |
279 |
 Soil Samples |
46 |
 Animal Samples |
7969 |
 Plant Samples |
42 |
| Total Samples | 8336 |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Physical-Chemical Aspects of the Preparation and Drug Release of Electrospun Scaffolds. | Cui L, Molnar JR, Budai-Szucs M, Szecsenyi M, Burian K, Valyi P, Berko S, Pukanszky B. | Pharmaceutics | 10.3390/pharmaceutics13101645 | 2021 | | |
| Electrospun Scaffolds in Periodontal Wound Healing. | Budai-Szucs M, Ruggeri M, Faccendini A, Leber A, Rossi S, Varga G, Bonferoni MC, Valyi P, Burian K, Csanyi E, Sandri G, Ferrari F. | Polymers (Basel) | 10.3390/polym13020307 | 2021 | | |
| O-Polysaccharide Plays a Major Role on the Virulence and Immunostimulatory Potential of Aggregatibacter actinomycetemcomitans During Periodontal Infection. | Monasterio G, Castillo F, Astorga J, Hoare A, Terraza-Aguirre C, Cafferata EA, Villablanca EJ, Vernal R. | Front Immunol | 10.3389/fimmu.2020.591240 | 2020 | | |
| Electrospun PLA Fibers Containing Metronidazole for Periodontal Disease. | Budai-Szucs M, Leber A, Cui L, Jozo M, Valyi P, Burian K, Kirschweng B, Csanyi E, Pukanszky B. | Drug Des Devel Ther | 10.2147/dddt.s231748 | 2020 | | |
| Metabolism | Inflammatory bone loss in experimental periodontitis induced by Aggregatibacter actinomycetemcomitans in interleukin-1 receptor antagonist knockout mice. | Izawa A, Ishihara Y, Mizutani H, Kobayashi S, Goto H, Okabe E, Takeda H, Ozawa Y, Kamiya Y, Sugita Y, Kubo K, Kamei H, Kikuchi T, Mitani A, Hayashi J, Nishihara T, Maeda H, Noguchi T. | Infect Immun | 10.1128/iai.01618-13 | 2014 | |
| Metabolism | Quantitative discrimination of Aggregatibacter actinomycetemcomitans highly leukotoxic JP2 clone from non-JP2 clones in diagnosis of aggressive periodontitis. | Yoshida A, Ennibi OK, Miyazaki H, Hoshino T, Hayashida H, Nishihara T, Awano S, Ansai T. | BMC Infect Dis | 10.1186/1471-2334-12-253 | 2012 | |
| Pathogenicity | Effect of smokeless tobacco products on human oral bacteria growth and viability. | Liu M, Jin J, Pan H, Feng J, Cerniglia CE, Yang M, Chen H. | Anaerobe | 10.1016/j.anaerobe.2016.10.006 | 2016 | |
| Genetic basis for conversion of rough-to-smooth colony morphology in Actinobacillus actinomycetemcomitans. | Wang Y, Liu A, Chen C. | Infect Immun | 10.1128/iai.73.6.3749-3753.2005 | 2005 | | |
| Phylogeny | Identification of Actinobacillus actinomycetemcomitans serotypes by multiplex PCR. | Suzuki N, Nakano Y, Yoshida Y, Ikeda D, Koga T. | J Clin Microbiol | 10.1128/jcm.39.5.2002-2005.2001 | 2001 | |
| Identification of genomic clonal types of Actinobacillus actinomycetemcomitans by restriction endonuclease analysis. | Han N, Hoover CI, Winkler JR, Ng CY, Armitage GC. | J Clin Microbiol | 10.1128/jcm.29.8.1574-1578.1991 | 1991 | | |
| Phylogeny | Population structure and genetic diversity of Actinobacillus actinomycetemcomitans strains isolated from localized juvenile periodontitis patients. | Kaplan JB, Schreiner HC, Furgang D, Fine DH. | J Clin Microbiol | 10.1128/jcm.40.4.1181-1187.2002 | 2002 | |
| Genetics | Evaluating two methods for fingerprinting genomes of Actinobacillus actinomycetemcomitans. | Slots J, Liu YB, DiRienzo JM, Chen C. | Oral Microbiol Immunol | 10.1111/j.1399-302x.1993.tb00608.x | 1993 | |
| Enzymology | Intracellular Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in buccal epithelial cells collected from human subjects. | Rudney JD, Chen R, Sedgewick GJ. | Infect Immun | 10.1128/iai.69.4.2700-2707.2001 | 2001 | |
| Phylogeny | Rapid identification of Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, and Haemophilus paraphrophilus by restriction enzyme analysis of PCR-amplified 16S rRNA genes. | Riggio MP, Lennon A. | J Clin Microbiol | 10.1128/jcm.35.6.1630-1632.1997 | 1997 | |
| Metabolism | Intra- and interspecies regulation of gene expression by Actinobacillus actinomycetemcomitans LuxS. | Fong KP, Chung WO, Lamont RJ, Demuth DR. | Infect Immun | 10.1128/iai.69.12.7625-7634.2001 | 2001 | |
| Enzymology | Detection and strain identification of Actinobacillus actinomycetemcomitans by nested PCR. | Leys EJ, Griffen AL, Strong SJ, Fuerst PA. | J Clin Microbiol | 10.1128/jcm.32.5.1288-1294.1994 | 1994 | |
| Improved multiplex PCR using conserved and species-specific 16S rRNA gene primers for simultaneous detection of Actinobacillus actinomycetemcomitans, Bacteroides forsythus, and Porphyromonas gingivalis. | Tran SD, Rudney JD. | J Clin Microbiol | 10.1128/jcm.37.11.3504-3508.1999 | 1999 | | |
| Enzymology | Multiplex PCR using conserved and species-specific 16S rRNA gene primers for simultaneous detection of Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis. | Tran SD, Rudney JD. | J Clin Microbiol | 10.1128/jcm.34.11.2674-2678.1996 | 1996 | |
| Regulation of Actinobacillus actinomycetemcomitans leukotoxin expression: analysis of the promoter regions of leukotoxic and minimally leukotoxic strains. | Brogan JM, Lally ET, Poulsen K, Kilian M, Demuth DR. | Infect Immun | 10.1128/iai.62.2.501-508.1994 | 1994 | | |
| Pathogenicity | Effect of eel galectin AJL-1 on periodontopathic bacterial biofilm formation and their lipopolysaccharide-mediated inflammatory cytokine induction. | Takayama S, Saitoh E, Kimizuka R, Yamada S, Kato T | Int J Antimicrob Agents | 10.1016/j.ijantimicag.2009.04.003 | 2009 | |
| Metabolism | Differential effects of five Aggregatibacter actinomycetemcomitans strains on gingival epithelial cells. | Shimada T, Sugano N, Nishihara R, Suzuki K, Tanaka H, Ito K | Oral Microbiol Immunol | 10.1111/j.1399-302X.2008.00449.x | 2008 | |
| Phylogeny | Phylogeny of 54 representative strains of species in the family Pasteurellaceae as determined by comparison of 16S rRNA sequences. | Dewhirst FE, Paster BJ, Olsen I, Fraser GJ | J Bacteriol | 10.1128/jb.174.6.2002-2013.1992 | 1992 | |
| Enzymology | Chemical composition and immunobiological activities of sodium dodecyl sulphate extracts from the cell envelopes of Actinobacillus actinomycetemcomitans, Bacteroides gingivalis and Fusobacterium nucleatum. | Kato K, Kokeguchi S, Ishihara H, Murayama Y, Tsujimoto M, Takada H, Ogawa T, Kotani S | J Gen Microbiol | 10.1099/00221287-133-4-1033 | 1987 | |
| Metabolism | Characterization of an inducible bacteriophage from a leukotoxic strain of Actinobacillus actinomycetemcomitans. | Stevens RH, Hammond BF, Lai CH | Infect Immun | 10.1128/iai.35.1.343-349.1982 | 1982 | |
| Enzymology | Molecular genotyping of isolates of Actinobacillus actinomycetemcomitans by pulsed-field gel electrophoresis after separate digestion with Sse8387I and XhoI. | Matsuda M, Takayama K, Haga S, Kagawa S, Ohta H, Fukui K, Moore JE | J Basic Microbiol | 10.1002/1521-4028(200205)42:2<137::AID-JOBM137>3.0.CO;2-8 | 2002 | |
| Pathogenicity | Absence of an especially toxic clone among isolates of Actinobacillus actinomycetemcomitans recovered from army recruits. | Macheleidt A, Muller HP, Eger T, Putzker M, Fuhrmann A, Zoller L | Clin Oral Investig | 10.1007/s007840050096 | 1999 | |
| Phylogeny | Multivariate chemosystematics demonstrate two groups of Actinobacillus actinomycetemcomitans strains. | Brondz I, Olsen I | Oral Microbiol Immunol | 10.1111/j.1399-302x.1993.tb00654.x | 1993 | |
| Metabolism | Serology of oral Actinobacillus actinomycetemcomitans and serotype distribution in human periodontal disease. | Zambon JJ, Slots J, Genco RJ | Infect Immun | 10.1128/iai.41.1.19-27.1983 | 1983 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive11753.20251217.10
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
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