Nocardiopsis halophila (DSM 44494, AS 4.1195, JCM 9892)

Name: Nocardiopsis halophila (DSM 44494, AS 4.1195, JCM 9892)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 11198

Type strain

Strain Designation IQ-H3

Culture col. no. DSM 44494 AS 4.1195 JCM 9892 IQ-H3 BCRC 16264 3 more

NCBI tax ID(s) 1245472 141692

Special Collections DSMZ JCM KCTC Wink compendium

History DSMZ <- JCM <- AS <- A. M. Al-Tai; IQ-H3 JCM <-- AS 4.1195 <-- A. M. Al-Tai IQ-H3.

Links

Nocardiopsis halophila IQ-H3 is a bacterium that builds an aerial mycelium and was isolated from saline soil.

genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 50654

DSM 44494,JCM 9892,AS 4.1195,KCTC 9825,BCRC 16264,CCRC 16264,CGMCC 4.1195

@ref 20215

Last LPSN update 2026-05-29 08:27:30

Domain Bacteria

Phylum Actinomycetota

Class Actinomycetes

Order Streptosporangiales

Family Nocardiopsidaceae

Genus Nocardiopsis

Species Nocardiopsis halophila

Full scientific name Nocardiopsis halophila Al-Tai and Ruan 1994

Synonyms (1)

Nocardiopsis baichengensis

BacDive ID	Other strains from **Nocardiopsis halophila** (1)	Type strain
11220	N. halophila DSM 44845, CCTCC AA 2040016, CIP 109298, ...

Morphology

Cell morphology

@ref	Gram stain	Confidence	Motility
125439	positive	94.324
125438		91.5

Colony morphology

@ref	Colony color	Medium used
69356	Brown beige (1011)	suter with tyrosine
69356	Beige (1001)	suter without tyrosine
69356	Ivory (1014)	ISP 3
69356	Light ivory (1015)	ISP 4
69356	Light ivory (1015), ochre yellow (1024)	ISP 7
69356	Sand yellow (1002)	ISP 2
69356	Sand yellow (1002)	ISP 5
69356	Sand yellow (1002)	ISP 6

Multicellular morphology

@ref	Complex name	Complex color	Medium name
69356	Aerial mycelium	Pure white (9010)	ISP 2
69356	Aerial mycelium	Signal white (9003)	ISP 3
69356	Aerial mycelium	Signal white (9003)	ISP 4
69356	Aerial mycelium	Signal white (9003)	ISP 5
69356	Aerial mycelium		ISP 6
69356	Aerial mycelium		ISP 7
69356	Aerial mycelium	Signal white (9003)	suter with tyrosine
69356	Aerial mycelium	Signal white (9003)	suter without tyrosine

Pigmentation

@ref	Production	Name
69356		melanin pigment
69356		soluble pigment

Multimedia

@ref:	11818
multimedia content:	DSM_44494.jpg
multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_44494.jpg
caption:	Medium 1240 28°C
intellectual property rights:	© Leibniz-Institut DSMZ
manual_annotation:	1

@ref:	69356
multimedia content:	DSM_44494_image3.png
multimedia.multimedia content:	DSM_44494_image3.png
caption:	Plates (1240, ISP2, ISP3, ISP4, ISP5, ISP7)
intellectual property rights:	Helmholtz-Zentrum für Infektionsforschung GmbH
manual_annotation:	1

@ref:	69356
multimedia content:	DSM_44494_image4.jpeg
multimedia.multimedia content:	DSM_44494_image4.jpeg
caption:	Plates (1240, ISP2, ISP3, ISP4, ISP5, ISP7)
intellectual property rights:	Helmholtz-Zentrum für Infektionsforschung GmbH
manual_annotation:	1

Culture and growth conditions

Culture medium

@ref	Name	Growth	Medium link	Composition
11818	STARCH-MINERAL SALT-AGAR (STMS) + 10%NACL (DSMZ Medium 1240)		Medium recipe at MediaDive	Name: STARCH-MINERAL SALT-AGAR + 10% NACL (DSMZ Medium 1240) Composition: NaCl 100.0 g/l Agar 15.0 g/l Starch 10.0 g/l (NH4)2SO4 2.0 g/l CaCO3 2.0 g/l K2HPO4 1.0 g/l MgSO4 x 7 H2O 1.0 g/l FeSO4 x 7 H2O 0.001 g/l MnCl2 x 4 H2O 0.001 g/l ZnSO4 x 7 H2O 0.001 g/l Distilled water
11818	CM + YE MEDIUM (DSMZ Medium 549)		Medium recipe at MediaDive	Name: CM + YE MEDIUM (DSMZ Medium 549) Composition: NaCl 200.0 g/l MgSO4 x 7 H2O 20.0 g/l Agar 15.0 g/l Yeast extract 10.0 g/l Casamino acids 7.5 g/l Na3-citrate 3.0 g/l KCl 2.0 g/l FeSO4 x 7 H2O 0.01 g/l HCl 3.646e-05 g/l Distilled water

Culture temp

@ref	Growth	Type	Temperature (°C)
11818	positive	growth	28
67770	positive	growth	28

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
125438	aerobe	93.164
125439	obligate aerobe	97.409

Halophily

@ref	Salt	Growth	Tested relation	Concentration
69356	NaCl	positive	growth	0-10 %

Observation

67770

Observationquinones: MK-10(H₆), MK-10(H₈)

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
69356	22599 ChEBI	arabinose	+	growth
69356	62968 ChEBI	cellulose	-	growth
68379	17634 ChEBI	D-glucose	-	fermentation	from API Coryne
68379	16899 ChEBI	D-mannitol	-	fermentation	from API Coryne
68379	16988 ChEBI	D-ribose	-	fermentation	from API Coryne
68379	65327 ChEBI	D-xylose	-	fermentation	from API Coryne
68379	4853 ChEBI	esculin	-	hydrolysis	from API Coryne
69356	28757 ChEBI	fructose	+	growth
68379	5291 ChEBI	gelatin	+	hydrolysis	from API Coryne
69356	17234 ChEBI	glucose	+	growth
68379	28087 ChEBI	glycogen	-	fermentation	from API Coryne
68379	17716 ChEBI	lactose	-	fermentation	from API Coryne
68379	17306 ChEBI	maltose	-	fermentation	from API Coryne
69356	37684 ChEBI	mannose	+/-	growth
69356	17268 ChEBI	myo-inositol	-	growth
68379	17632 ChEBI	nitrate	+	reduction	from API Coryne
69356	16634 ChEBI	raffinose	-	growth
69356	26546 ChEBI	rhamnose	+/-	growth
69356	17992 ChEBI	sucrose	+/-	growth
68379	17992 ChEBI	sucrose	-	fermentation	from API Coryne
69356	18222 ChEBI	xylose	+	growth

Enzymes

@ref	Value	Activity	Ec
68382	alkaline phosphatase	+	3.1.3.1	from API zym
68379	alkaline phosphatase	+	3.1.3.1	from API Coryne
68382	alpha-chymotrypsin	+	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68379	alpha-glucosidase	-	3.2.1.20	from API Coryne
68382	alpha-mannosidase	+	3.2.1.24	from API zym
68379	beta-galactosidase	+	3.2.1.23	from API Coryne
68382	beta-galactosidase	-	3.2.1.23	from API zym
68382	beta-glucosidase	+	3.2.1.21	from API zym
68379	beta-glucosidase	-	3.2.1.21	from API Coryne
68382	beta-glucuronidase	-	3.2.1.31	from API zym
68379	beta-glucuronidase	-	3.2.1.31	from API Coryne
68382	esterase (C 4)	+		from API zym
68379	gelatinase	+		from API Coryne
68382	leucine arylamidase	+	3.4.11.1	from API zym
68382	N-acetyl-beta-glucosaminidase	+	3.2.1.52	from API zym
68379	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API Coryne
68382	naphthol-AS-BI-phosphohydrolase	-		from API zym
68379	pyrazinamidase	-	3.5.1.B15	from API Coryne
68379	pyrrolidonyl arylamidase	+	3.4.19.3	from API Coryne
68382	valine arylamidase	+		from API zym

API coryne

@ref	Reduction of nitrateNIT	PYZ	PYRA	PAL	beta GUR	beta GAL	alpha GLU	beta NAG	ESC	URE	GEL	Control fermentationControl	GLU	RIB	XYL	MAN	MAL	LAC	SAC	GLYG	CAT
69356	+	-	+	+	-	+	-	-	-	+/-	+	not determinedn.d.	-	-	-	-	-	-	-	-	not determinedn.d.

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
69356	not determinedn.d.	+	+	+/-	+/-	+	+	+/-	+/-	+	+/-	-	-	-	-	+/-	+	+	+	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Environmental	#Terrestrial	#Soil
#Condition	#Saline	-

Isolation

@ref	Sample type	Country	Country ISO 3 Code	Continent
11818	saline soil	Iraq	IRQ	Asia
67770	Saline soil	Iraq	IRQ	Asia

Taxonmaps

69479

Global distribution of 16S sequence AF195411 (>99% sequence identity) for Nocardiopsis from Microbeatlas

Aquatic Samples	3
Soil Samples	28
Animal Samples	25
Plant Samples	3
Total Samples	59

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
11818	1	Risk group (German classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
67770	SOAPdenovo v1.06 assembly for Nocardiopsis halophila DSM 44494	contig	GCA_000341245	1245472.3	2554235470	1245472	12.99

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
20218	Nocardiopsis halophila partial 16S rRNA gene, strain DSM 44494T	AJ421018	1505		1245472
20218	Nocardiopsis halophila 16S ribosomal RNA gene, partial sequence	AF195411	1478		1245472

GC content

@ref	GC-content (mol%)	Method
67770	73.7	genome sequence analysis

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: SOAPdenovo v1.06 assembly for Nocardiopsis halophila DSM 44494
BV-BRC: 1245472.3

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	gram_stain	BacteriaNetⓘ	positive	94.32	no
125439	oxygen_tolerance	BacteriaNetⓘ	obligate aerobe	97.41	no
125439	motility	BacteriaNetⓘ	no	85.70	no
125439	spore_formation	BacteriaNetⓘ	yes	69.04	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Nocardiopsis halophila DSM 44494
PATRIC: 1245472.3

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	89.81	no
125438	anaerobic	anaerobicⓘ	no	97.19	no
125438	spore-forming	spore-formingⓘ	yes	82.76	no
125438	aerobic	aerobicⓘ	yes	93.16	no
125438	thermophilic	thermophileⓘ	no	94.25	no
125438	flagellated	motile2+ⓘ	no	91.50	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	Repurposing endogenous type I-E CRISPR-Cas systems for natural product discovery in Streptomyces.	Zhou Q, Zhao Y, Ke C, Wang H, Gao S, Li H, Zhang Y, Ye Y, Luo Y.	Nat Commun	10.1038/s41467-024-54196-z	2024
Genetics	Genome-Based Taxonomic Classification of the Phylum Actinobacteria.	Nouioui I, Carro L, Garcia-Lopez M, Meier-Kolthoff JP, Woyke T, Kyrpides NC, Pukall R, Klenk HP, Goodfellow M, Goker M.	Front Microbiol	10.3389/fmicb.2018.02007	2018
	Role of Resuscitation Promoting Factor-like Protein from Nocardiopsis halophila.	Zhang Y, Liu J, Cao M, Zhang Y, Zhang X.	Microorganisms	10.3390/microorganisms11020485	2023
	Nutritional Composition of Apis mellifera Drones from Korea and Denmark as a Potential Sustainable Alternative Food Source: Comparison Between Developmental Stages.	Ghosh S, Sohn HY, Pyo SJ, Jensen AB, Meyer-Rochow VB, Jung C.	Foods	10.3390/foods9040389	2020
Pathogenicity	New antimicrobial peptide kills drug-resistant pathogens without detectable resistance.	Lee JK, Luchian T, Park Y.	Oncotarget	10.18632/oncotarget.24582	2018
Phylogeny	Genome analysis reveals that Nocardiopsis baichengensis Li et al. 2006 is a later heterotypic synonym of Nocardiopsis halophila Al-Tai and Ruan 1994.	Zhang XT, Salam N, Xiao M, Asem MD, Li WJ	Int J Syst Evol Microbiol	10.1099/ijsem.0.003721	2020
	Nocardiopsis suaedae sp. nov. and Nocardiopsis endophytica sp. nov., two novel halophilic actinobacteria isolated from halophytes.	Chantavorakit T, Suriyachadkun C, Hong K, Duangmal K.	Int J Syst Evol Microbiol	10.1099/ijsem.0.005948	2023

References

#11818	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 44494
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68379	Automatically annotated from API Coryne .
#68382	Automatically annotated from API zym .
#69356	Wink, J.: Compendium of Actinobacteria. HZI-Helmholtz-Centre for Infection Research, Braunschweig .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

Content

About us

Nocardiopsis halophila (DSM 44494, AS 4.1195, JCM 9892)

Name and taxonomic classification

Morphology

Cell morphology

Colony morphology

Multicellular morphology

Pigmentation

Multimedia

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Halophily

Observation

Metabolite utilization

Enzymes

API coryne

API zym

Isolation, sampling and environmental information

Isolation source categories

Isolation

Taxonmaps

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_000341245

16S sequences

GC content

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

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