Name: Halalkalibacterium halodurans C-125
Creator: BacDive
License: http://creativecommons.org/licenses/by-nc/4.0/

Strain identifier

BacDive ID: 1119

Type strain:

Species: Halalkalibacterium halodurans

Strain Designation: C-125

Culture col. no.: DSM 18197, ATCC BAA-125, JCM 9153, CGMCC 1.6354, FERM 7344

Strain history: K. Horikoshi C-125.

NCBI tax ID(s): 86665 (species)

Other strains from Halalkalibacterium halodurans

Section

Halalkalibacterium halodurans C-125 is a mesophilic bacterium that was isolated from soil.

mesophilic
16S sequence
Bacteria
genome sequence

Information on the name and the taxonomic classification. Name and taxonomic classification

	Last LPSN update	14-12-2023 (DD-MM-YYYY)
	Domain	"Bacteria"
	Phylum	*Bacillota*
	Class	*Bacilli*
	Order	*Caryophanales*
	Family	*Bacillaceae*
	Genus	*Halalkalibacterium*
	Species	**Halalkalibacterium halodurans**
	Full Scientific Name (LPSN)	Halalkalibacterium halodurans (Nielsen et al. 1995 ex Boyer et al. 1973) Joshi et al. 2022

	Synonym	"Bacillus* alcalophilus subsp. halodurans"*
	Synonym	Bacillus okuhidensis
	Synonym	Bacillus halodurans
	Synonym	Alkalihalobacillus halodurans
	Synonym	Alkalihalobacillus okuhidensis

Information on culture and growth conditions Culture and growth conditions

[Ref.: #7421]

Culture medium

ALKALINE NUTRIENT AGAR (DSMZ Medium 31)

[Ref.: #7421]

Culture medium growth

[Ref.: #7421]

Culture medium link

Medium recipe at MediaDive

[Ref.: #7421]

Culture medium composition

expand / minimize

	Temperatures	Kind of temperature		Temperature
[Ref.: #7421]			growth	30 °C
[Ref.: #67770]			growth	37 °C

[Ref.: #7421]	Temperature range	mesophilic
[Ref.: #67770]	Temperature range	mesophilic

Information on physiology and metabolism Physiology and metabolism

	Enzymes	Enzyme	EC number
[Ref.: #67770]		beta-galactosidase	3.2.1.23

Information on isolation source, the sampling and environmental conditions Isolation, sampling and environmental information

[Ref.: #7421]	Sample type/isolated from	soil
[Ref.: #7421]	Country	Japan
[Ref.: #7421]	Country ISO 3 Code	JPN
[Ref.: #7421]	Continent	Asia

[Ref.: #67770]	Sample type/isolated from	Soil
* marker position based on {}

Isolation sources categories

#Environmental

#Terrestrial

#Soil

What are isolation sources categories?

[Ref.: #69479]

Global distribution of 16S sequence AB598741 (>99% sequence identity) for Alkalihalobacillus halodurans from Microbeatlas

Aquatic Samples	1519
Soil Samples	1545
Animal Samples	3493
Plant Samples	429
Total Samples	6986

Information on possible application of the strain and its possible interaction with e.g. potential hosts Safety information

[Ref.: #7421]

Biosafety level

Risk group (German classification)
According to TRBA 466

Information on genomic background e.g. entries in nucleic sequence databass Sequence information

16S Sequence information:

	Sequence accession description	Seq. accession number	Sequence length (bp)	Sequence database	Associated NCBI tax ID
[Ref.: #20218]	Bacillus halodurans gene for 16S rRNA, partial sequence, strain: JCM 9153	AB598741	1413	ENA	86665 tax ID	*

Genome sequence information:

	Sequence accession description	Seq. accession number	Assembly level	Sequence database	Associated NCBI tax ID
[Ref.: #66792]	Halalkalibacterium halodurans C-125	GCA_000011145	complete	GenBank	272558 tax ID	*
[Ref.: #66792]	Alkalihalobacillus halodurans C-125	637000020	complete	JGI IMG/M	272558 tax ID	*

Data predicted using genome information as a basis Genome-based predictions

	Trait	Prediction	Confidence in %	In training data
	Predictions from Diaspora project based on: Alkalihalobacillus halodurans C-125 C-125 NCBI: GCA_000011145.1
[Ref.: #69480]	motile	yes	90.753	no
[Ref.: #69480]	flagellated	yes	84.567	no
[Ref.: #69480]	gram-positive	yes	86.662	no
[Ref.: #69480]	anaerobic	no	98.401	no
[Ref.: #69480]	halophile	yes	71.387	no
[Ref.: #69480]	spore-forming	yes	95.763	no
[Ref.: #69480]	thermophile	no	89.057	yes
[Ref.: #69480]	glucose-util	yes	91.589	no
[Ref.: #69480]	aerobic	yes	87.261	no
[Ref.: #69480]	glucose-ferment	no	92.18	no

Availability in culture collections External links

[Ref.: #7421]

Culture collection no.

DSM 18197, ATCC BAA-125, JCM 9153, CGMCC 1.6354, FERM 7344

Literature:

Only first 10 entries are displayed. Click here to see all.

Topic	Title	Authors	Journal	DOI	Year
Enzymology	Molecular cloning and characterization of a novel xylanase from Microbacterium imperiale YD-01.	Tang K, Cui Y, Xiao J, Ding M, Chao H, Wu J, Han Z, Liu J, Li X, Yan D	J Food Biochem	10.1111/jfbc.13988	2021	*
Enzymology	Substrate Specificities of GH8, GH39, and GH52 beta-xylosidases from Bacillus halodurans C-125 Toward Substituted Xylooligosaccharides.	Teramoto K, Tsutsui S, Sato T, Fujimoto Z, Kaneko S	Appl Biochem Biotechnol	10.1007/s12010-020-03451-2	2021	*
Enzymology	Homology modeling and heterologous expression of highly alkaline subtilisin-like serine protease from Bacillus halodurans C-125.	Tekin A, Uzuner U, Sezen K	Biotechnol Lett	10.1007/s10529-020-03025-6	2020	*
Enzymology	Functional Expression and Characterization of Acetyl Xylan Esterases CE Family 7 from Lactobacillus antri and Bacillus halodurans.	Kim MJ, Jang MU, Nam GH, Shin H, Song JR, Kim TJ	J Microbiol Biotechnol	10.4014/jmb.2001.01004	2020	*
Enzymology	Characterization of recombinant endo-1,4-beta-xylanase of Bacillus halodurans C-125 and rational identification of hot spot amino acid residues responsible for enhancing thermostability by an in-silico approach.	Mahmood MS, Rasul F, Saleem M, Afroz A, Malik MF, Ashraf NM, Rashid U, Naz S, Zeeshan N	Mol Biol Rep	10.1007/s11033-019-04751-5	2019	*
Metabolism	Functional characterization of hormone sensitive-like lipase from Bacillus halodurans: synthesis and recovery of pNP-laurate with high yields.	Dua A, Gupta R	Extremophiles	10.1007/s00792-017-0949-8	2017	*
Metabolism	Redesigning pH optimum of Geobacillus sp. TF16 endoxylanase through in silico designed DNA swapping strategy.	Uzuner U, Canakci S, Bektas KI, Sapmaz MT, Belduz AO	Biochimie	10.1016/j.biochi.2017.03.017	2017	*
Pathogenicity	Narrow-spectrum inhibitors targeting an alternative menaquinone biosynthetic pathway of Helicobacter pylori.	Yamamoto T, Matsui H, Yamaji K, Takahashi T, Overby A, Nakamura M, Matsumoto A, Nonaka K, Sunazuka T, Omura S, Nakano H	J Infect Chemother	10.1016/j.jiac.2016.05.012	2016	*
Metabolism	Quantitative iTRAQ LC-MS/MS proteomics reveals the cellular response to heterologous protein overexpression and the regulation of HAC1 in Pichia pastoris.	Lin XQ, Liang SL, Han SY, Zheng SP, Ye YR, Lin Y	J Proteomics	10.1016/j.jprot.2013.06.031	2013	*
Metabolism	Enhanced 5-methylcytosine detection in single-molecule, real-time sequencing via Tet1 oxidation.	Clark TA, Lu X, Luong K, Dai Q, Boitano M, Turner SW, He C, Korlach J	BMC Biol	10.1186/1741-7007-11-4	2013	*
Enzymology	Bleach boosting effect of xylanase A from Bacillus halodurans C-125 in ECF bleaching of wheat straw pulp.	Lin XQ, Han SY, Zhang N, Hu H, Zheng SP, Ye YR, Lin Y	Enzyme Microb Technol	10.1016/j.enzmictec.2012.10.011	2012	*
Pathogenicity	OLE RNA protects extremophilic bacteria from alcohol toxicity.	Wallace JG, Zhou Z, Breaker RR	Nucleic Acids Res	10.1093/nar/gks352	2012	*
Enzymology	Structure-based function discovery of an enzyme for the hydrolysis of phosphorylated sugar lactones.	Xiang DF, Kolb P, Fedorov AA, Xu C, Fedorov EV, Narindoshivili T, Williams HJ, Shoichet BK, Almo SC, Raushel FM	Biochemistry	10.1021/bi201838b	2012	*
Metabolism	The relationship between a coiled morphology and Mbl in alkaliphilic Bacillus halodurans C-125 at neutral pH values.	Fujinami S, Sato T, Ito M	Extremophiles	10.1007/s00792-011-0389-9	2011	*
Enzymology	Multitechnique study on a recombinantly produced Bacillus halodurans laccase and an S-layer/laccase fusion protein.	Ferner-Ortner-Bleckmann J, Schrems A, Ilk N, Egelseer EM, Sleytr UB, Schuster B	Biointerphases	10.1116/1.3589284	2011	*
Enzymology	Characterization of a glucose-, xylose-, sucrose-, and D-galactose-stimulated beta-glucosidase from the alkalophilic bacterium Bacillus halodurans C-125.	Xu H, Xiong AS, Zhao W, Tian YS, Peng RH, Chen JM, Yao QH	Curr Microbiol	10.1007/s00284-010-9766-3	2010	*
Metabolism	The C-terminal coiled-coil of the bacterial voltage-gated sodium channel NaChBac is not essential for tetramer formation, but stabilizes subunit-to-subunit interactions.	Mio K, Mio M, Arisaka F, Sato M, Sato C	Prog Biophys Mol Biol	10.1016/j.pbiomolbio.2010.05.002	2010	*
Enzymology	Industrial applications of alkaliphiles and their enzymes--past, present and future.	Fujinami S, Fujisawa M	Environ Technol	10.1080/09593331003762807	2010	*
Enzymology	Enhanced production and characterization of a beta-glucosidase from Bacillus halodurans expressed in Escherichia coli.	Naz S, Ikram N, Rajoka MI, Sadaf S, Akhtar MW	Biochemistry (Mosc)	10.1134/s0006297910040164	2010	*
Metabolism	Expression and characterization of a xylosidase (Bxyl) from Bacillus halodurans C-125.	Liang Y, Li X, Shin H, Chen RR, Mao Z	Sheng Wu Gong Cheng Xue Bao		2009	*
Enzymology	Biocatalytic conversion of wheat bran hydrolysate using an immobilized GH43 beta-xylosidase.	Smaali I, Remond C, Skhiri Y, O'Donohue MJ	Bioresour Technol	10.1016/j.biortech.2008.06.041	2008	*
Pathogenicity	Antibacterial activity of cyclodextrins against Bacillus strains.	Zhang HM, Li Z, Uematsu K, Kobayashi T, Horikoshi K	Arch Microbiol	10.1007/s00203-008-0415-1	2008	*
Enzymology	Cloning, expression and characterization of a glycoside hydrolase family 39 xylosidase from Bacillus halodurans C-125.	Wagschal K, Franqui-Espiet D, Lee CC, Robertson GH, Wong DW	Appl Biochem Biotechnol	10.1007/s12010-007-8055-5	2007	*
Enzymology	Purification of two putative type II NADH dehydrogenases with different substrate specificities from alkaliphilic Bacillus pseudofirmus OF4.	Liu J, Krulwich TA, Hicks DB	Biochim Biophys Acta	10.1016/j.bbabio.2008.02.004	2008	*
Enzymology	Characterization of a new rhamnogalacturonan acetyl esterase from Bacillus halodurans C-125 with a new putative carbohydrate binding domain.	Navarro-Fernandez J, Martinez-Martinez I, Montoro-Garcia S, Garcia-Carmona F, Takami H, Sanchez-Ferrer A	J Bacteriol	10.1128/JB.01104-07	2007	*
Enzymology	Cloning, characterization, and expression of xylanase A gene from Paenibacillus sp. DG-22 in Escherichia coli.	Lee TH, Lim PO, Lee YE	J Microbiol Biotechnol		2007	*
Enzymology	Molecular anatomy of the alkaliphilic xylanase from Bacillus halodurans C-125.	Nishimoto M, Fushinobu S, Miyanaga A, Kitaoka M, Hayashi K	J Biochem	10.1093/jb/mvm072	2007	*
Enzymology	High-level heterologous expression of Bacillus halodurans putative xylanase xyn11a (BH0899) in Kluyveromyces lactis.	Wamalwa BM, Zhao G, Sakka M, Shiundu PM, Kimura T, Sakka K	Biosci Biotechnol Biochem	10.1271/bbb.60477	2007	*
Phylogeny	Isolation and identification of two xylanase-producing extremely alkali-tolerant strains of Bacillus halodurans from Turpan in China.	Yi X, Xie ZJ, Deng AH, Wang N, Erkin R	Wei Sheng Wu Xue Bao		2006	*
Genetics	Identification of a novel two-peptide lantibiotic, haloduracin, produced by the alkaliphile Bacillus halodurans C-125.	Lawton EM, Cotter PD, Hill C, Ross RP	FEMS Microbiol Lett	10.1111/j.1574-6968.2006.00539.x	2007	*
Metabolism	Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic.	McClerren AL, Cooper LE, Quan C, Thomas PM, Kelleher NL, van der Donk WA	Proc Natl Acad Sci U S A	10.1073/pnas.0606088103	2006	*
Enzymology	Cloning and characterization of dihydrofolate reductase from a facultative alkaliphilic and halotolerant bacillus strain.	Redecke L, Brehm MA, Bredehorst R	Extremophiles	10.1007/s00792-006-0013-6	2006	*
Phylogeny	Expression in Escherichia coli and characterization of beta-xylosidases GH39 and GH-43 from Bacillus halodurans C-125.	Smaali I, Remond C, O'Donohue MJ	Appl Microbiol Biotechnol	10.1007/s00253-006-0512-5	2006	*
Enzymology	A primary sodium pump gene of the moderate halophile Halobacillus dabanensis exhibits secondary antiporter properties.	Yang L, Jiang J, Zhang B, Zhao B, Wang L, Yang SS	Biochem Biophys Res Commun	10.1016/j.bbrc.2006.05.181	2006	*
Enzymology	Crystallization and preliminary X-ray analysis of reducing-end xylose-releasing exo-oligoxylanase from Bacillus halodurans C-125.	Honda Y, Fushinobu S, Hidaka M, Wakagi T, Shoun H, Kitaoka M	Acta Crystallogr Sect F Struct Biol Cryst Commun	10.1107/S1744309105003635	2005	*
Enzymology	Employing chimeric xylanases to identify regions of an alkaline xylanase participating in enzyme activity at basic pH.	Nishimoto M, Kitaoka M, Hayashi K	J Biosci Bioeng	S1389-1723(02)80215-8	2002	*
Metabolism	A structural and functional analysis of alpha-glucan recognition by family 25 and 26 carbohydrate-binding modules reveals a conserved mode of starch recognition.	Boraston AB, Healey M, Klassen J, Ficko-Blean E, Lammerts van Bueren A, Law V	J Biol Chem	10.1074/jbc.M509958200	2005	*
Enzymology	An alkali-inducible flotillin-like protein from Bacillus halodurans C-125.	Zhang HM, Li Z, Tsudome M, Ito S, Takami H, Horikoshi K	Protein J	10.1007/s10930-004-1519-3	2005	*
Genetics	A novel beta-glucanase gene from Bacillus halodurans C-125.	Akita M, Kayatama K, Hatada Y, Ito S, Horikoshi K	FEMS Microbiol Lett	10.1016/j.femsle.2005.05.009	2005	*
Enzymology	The role of conserved arginine residue in loop 4 of glycoside hydrolase family 10 xylanases.	Nishimoto M, Kitaoka M, Fushinobu S, Hayashi K	Biosci Biotechnol Biochem	10.1271/bbb.69.904	2005	*
Enzymology	Structural basis for the specificity of the reducing end xylose-releasing exo-oligoxylanase from Bacillus halodurans C-125.	Fushinobu S, Hidaka M, Honda Y, Wakagi T, Shoun H, Kitaoka M	J Biol Chem	10.1074/jbc.M413693200	2005	*
Enzymology	A family 8 glycoside hydrolase from Bacillus halodurans C-125 (BH2105) is a reducing end xylose-releasing exo-oligoxylanase.	Honda Y, Kitaoka M	J Biol Chem	10.1074/jbc.M409832200	2004	*
Stress	Wide-range distribution of insertion sequences identified in B. halodurans among bacilli and a new transposon disseminated in alkaliphilic and thermophilic bacilli.	Takami H, Matsuki A, Takaki Y	DNA Res	10.1093/dnares/11.3.153	2004	*
Enzymology	A cloned Bacillus halodurans multicopper oxidase exhibiting alkaline laccase activity.	Ruijssenaars HJ, Hartmans S	Appl Microbiol Biotechnol	10.1007/s00253-004-1571-0	2004	*
Enzymology	Characterization of endo-beta-N-acetylglucosaminidase from alkaliphilic Bacillus halodurans C-125.	Fujita K, Takami H, Yamamoto K, Takegawa K	Biosci Biotechnol Biochem	10.1271/bbb.68.1059	2004	*
Enzymology	The BH1999 protein of Bacillus halodurans C-125 is gentisyl-coenzyme A thioesterase.	Zhuang Z, Song F, Takami H, Dunaway-Mariano D	J Bacteriol	10.1128/JB.186.2.393-399.2004	2004	*
Metabolism	A globin-coupled oxygen sensor from the facultatively alkaliphilic Bacillus halodurans C-125.	Hou S, Belisle C, Lam S, Piatibratov M, Sivozhelezov V, Takami H, Alam M	Extremophiles	10.1007/s007920100220	2001	*
Genetics	Identification and distribution of new insertion sequences in the genome of alkaliphilic Bacillus halodurans C-125.	Takami H, Han CG, Takaki Y, Ohtsubo E	J Bacteriol	10.1128/JB.183.14.4345-4356.2001	2001	*
Metabolism	The Na(+)-dependence of alkaliphily in Bacillus.	Krulwich TA, Ito M, Guffanti AA	Biochim Biophys Acta	10.1016/s0005-2728(00)00285-1	2001	*
Genetics	Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis.	Takami H, Nakasone K, Takaki Y, Maeno G, Sasaki R, Masui N, Fuji F, Hirama C, Nakamura Y, Ogasawara N, Kuhara S, Horikoshi K	Nucleic Acids Res	10.1093/nar/28.21.4317	2000	*
Metabolism	The Na+/H+ antiporter of alkaliphilic Bacillus sp.	Kitada M, Kosono S, Kudo T	Extremophiles	10.1007/s007920070010	2000	*
Enzymology	Characterization and comparative study of the rrn operons of alkaliphilic Bacillus halodurans C-125.	Nakasone K, Masui N, Takaki Y, Sasaki R, Maeno G, Sakiyama T, Hirama C, Fuji F, Takami H	Extremophiles	10.1007/pl00010713	2000	*
Metabolism	Analysis of the genome of an alkaliphilic Bacillus strain from an industrial point of view.	Takami H, Horikoshi K	Extremophiles	10.1007/s007920050143	2000	*
Genetics	An automated system for genome analysis to support microbial whole-genome shotgun sequencing.	Sakiyama T, Takami H, Ogasawara N, Kuhara S, Kozuki T, Doga K, Ohyama A, Horikoshi K	Biosci Biotechnol Biochem	10.1271/bbb.64.670	2000	*
Enzymology	Genetic analysis of the chromosome of alkaliphilic Bacillus halodurans C-125.	Takami H, Takaki Y, Nakasone K, Sakiyama T, Maeno G, Sasaki R, Hirama C, Fuji F, Masui N	Extremophiles	10.1007/s007920050120	1999	*
Genetics	Replication origin region of the chromosome of alkaliphilic Bacillus halodurans C-125.	Takami H, Masui N, Nakasone K, Horikoshi K	Biosci Biotechnol Biochem	10.1271/bbb.63.1134	1999	*
	Assessment of a Potential Role of Dickeya dadantii DSM 18020 as a Pectinase Producer for Utilization in Poultry Diets Based on in silico Analyses.	Dittoe DK, Barabote RD, Rothrock MJ, Ricke SC	Front Microbiol	10.3389/fmicb.2020.00751	2020	*
	Mrp Antiporters Have Important Roles in Diverse Bacteria and Archaea.	Ito M, Morino M, Krulwich TA	Front Microbiol	10.3389/fmicb.2017.02325	2017	*
	4-O-Methyl Modifications of Glucuronic Acids in Xylans Are Indispensable for Substrate Discrimination by GH67 alpha-Glucuronidase from Bacillus halodurans C-125.	Yagi H, Maehara T, Tanaka T, Takehara R, Teramoto K, Yaoi K, Kaneko S	J Appl Glycosci (1999)	10.5458/jag.jag.JAG-2017_016	2017	*
	Improved genetic transformation methods for the model alkaliphile Bacillus halodurans C-125.	Wallace JG, Breaker RR	Lett Appl Microbiol	10.1111/j.1472-765X.2011.03017.x	2011	*
	A kinetic study on pH-activity relationship of XynA from alkaliphilic Bacillus halodurans C-125 using aryl-xylobiosides.	Nishimoto M, Honda Y, Kitaoka M, Hayashi K	J Biosci Bioeng	10.1016/s1389-1723(02)80079-2	2002	*
	Reidentification of Facultatively Alkaliphilic Bacillus sp. C-125 to Bacillus halodurans.	Takami H, Horikoshi K	Biosci Biotechnol Biochem	10.1271/bbb.63.943	1999	*
	Characteristics of the ErmK Protein of Bacillus halodurans C-125.	Kim SK, Min YH, Jin HJ	Microbiol Spectr	10.1128/spectrum.02598-22	2022	*

References

#7421

Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 18197

#20215

Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )

#20218

Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )

#66792

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#67770 Japan Collection of Microorganism (JCM) ; Curators of the JCM;

#69479

João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .

#69480

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

* These data were automatically processed and therefore are not curated

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Alkalihalobacillus halodurans C-125 C-125

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