Nocardia cyriacigeorgica DSM 44484 is an aerobe, mesophilic, Gram-positive prokaryote that was isolated from bronchial secretions.
Gram-positive aerobe mesophilic genome sequence 16S sequence| @ref 20215 |
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| Domain Bacteria |
| Phylum Actinomycetota |
| Class Actinomycetes |
| Order Mycobacteriales |
| Family Nocardiaceae |
| Genus Nocardia |
| Species Nocardia cyriacigeorgica |
| Full scientific name Nocardia cyriacigeorgica corrig. Yassin et al. 2001 |
| Synonyms (1) |
| 118834 | Hemolysis ability1 |
| @ref: | 11810 |
| multimedia content: | DSM_44484-1.jpg |
| multimedia.multimedia content: | https://www.dsmz.de/microorganisms/photos/DSM_44484-1.jpg |
| intellectual property rights: | © Leibniz-Institut DSMZ |
| manual_annotation: | 1 |
| @ref: | 11810 |
| multimedia content: | DSM_44484.jpg |
| multimedia.multimedia content: | https://www.dsmz.de/microorganisms/photos/DSM_44484.jpg |
| caption: | Medium 65 28°C |
| intellectual property rights: | © Leibniz-Institut DSMZ |
| manual_annotation: | 1 |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 11810 | GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) | Medium recipe at MediaDive | Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 18.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water | ||
| 39919 | MEDIUM 72- for trypto casein soja agar | Distilled water make up to (1000.000 ml);Trypto casein soy agar (40.000 g) | |||
| 118834 | CIP Medium 72 | Medium recipe at CIP |
| 67770 | Observationquinones: MK-8(H6, ω-cycl), 2,3-epoxy-MK-8(H6, ω-cycl) |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68371 | 27613 ChEBI | amygdalin | - | builds acid from | from API 50CH acid |
| 68371 | 18305 ChEBI | arbutin | + | builds acid from | from API 50CH acid |
| 68371 | 17057 ChEBI | cellobiose | - | builds acid from | from API 50CH acid |
| 118834 | 16947 ChEBI | citrate | - | carbon source | |
| 68371 | 17108 ChEBI | D-arabinose | - | builds acid from | from API 50CH acid |
| 68371 | 18333 ChEBI | D-arabitol | - | builds acid from | from API 50CH acid |
| 68371 | 15824 ChEBI | D-fructose | + | builds acid from | from API 50CH acid |
| 68371 | 28847 ChEBI | D-fucose | - | builds acid from | from API 50CH acid |
| 68371 | 12936 ChEBI | D-galactose | - | builds acid from | from API 50CH acid |
| 68371 | 17634 ChEBI | D-glucose | - | builds acid from | from API 50CH acid |
| 68371 | 62318 ChEBI | D-lyxose | - | builds acid from | from API 50CH acid |
| 68371 | 16899 ChEBI | D-mannitol | - | builds acid from | from API 50CH acid |
| 68371 | 16024 ChEBI | D-mannose | - | builds acid from | from API 50CH acid |
| 68371 | 17924 ChEBI | D-sorbitol | - | builds acid from | from API 50CH acid |
| 68371 | 16443 ChEBI | D-tagatose | - | builds acid from | from API 50CH acid |
| 68371 | 65327 ChEBI | D-xylose | - | builds acid from | from API 50CH acid |
| 68371 | 17113 ChEBI | erythritol | - | builds acid from | from API 50CH acid |
| 118834 | 4853 ChEBI | esculin | + | hydrolysis | |
| 68371 | 4853 ChEBI | esculin | - | builds acid from | from API 50CH acid |
| 68371 | 16813 ChEBI | galactitol | - | builds acid from | from API 50CH acid |
| 68371 | 28066 ChEBI | gentiobiose | - | builds acid from | from API 50CH acid |
| 68371 | 24265 ChEBI | gluconate | - | builds acid from | from API 50CH acid |
| 68371 | 17754 ChEBI | glycerol | - | builds acid from | from API 50CH acid |
| 118834 | 606565 ChEBI | hippurate | - | hydrolysis | |
| 68371 | 15443 ChEBI | inulin | - | builds acid from | from API 50CH acid |
| 68371 | 30849 ChEBI | L-arabinose | - | builds acid from | from API 50CH acid |
| 68371 | 18403 ChEBI | L-arabitol | - | builds acid from | from API 50CH acid |
| 68371 | 18287 ChEBI | L-fucose | - | builds acid from | from API 50CH acid |
| 68371 | 62345 ChEBI | L-rhamnose | - | builds acid from | from API 50CH acid |
| 68371 | 17266 ChEBI | L-sorbose | - | builds acid from | from API 50CH acid |
| 68371 | 65328 ChEBI | L-xylose | - | builds acid from | from API 50CH acid |
| 68371 | 17716 ChEBI | lactose | + | builds acid from | from API 50CH acid |
| 68371 | 17306 ChEBI | maltose | - | builds acid from | from API 50CH acid |
| 68371 | 6731 ChEBI | melezitose | - | builds acid from | from API 50CH acid |
| 68371 | 28053 ChEBI | melibiose | - | builds acid from | from API 50CH acid |
| 68371 | 320061 ChEBI | methyl alpha-D-glucopyranoside | - | builds acid from | from API 50CH acid |
| 68371 | 43943 ChEBI | methyl alpha-D-mannoside | - | builds acid from | from API 50CH acid |
| 68371 | 74863 ChEBI | methyl beta-D-xylopyranoside | - | builds acid from | from API 50CH acid |
| 68371 | 17268 ChEBI | myo-inositol | - | builds acid from | from API 50CH acid |
| 68371 | 59640 ChEBI | N-acetylglucosamine | - | builds acid from | from API 50CH acid |
| 118834 | 17632 ChEBI | nitrate | + | reduction | |
| 118834 | 17632 ChEBI | nitrate | - | respiration | |
| 118834 | 16301 ChEBI | nitrite | - | reduction | |
| 68371 | Potassium 2-ketogluconate | - | builds acid from | from API 50CH acid | |
| 68371 | Potassium 5-ketogluconate | - | builds acid from | from API 50CH acid | |
| 68371 | 16634 ChEBI | raffinose | - | builds acid from | from API 50CH acid |
| 68371 | 15963 ChEBI | ribitol | - | builds acid from | from API 50CH acid |
| 68371 | 17814 ChEBI | salicin | + | builds acid from | from API 50CH acid |
| 68371 | 28017 ChEBI | starch | + | builds acid from | from API 50CH acid |
| 68371 | 17992 ChEBI | sucrose | - | builds acid from | from API 50CH acid |
| 68371 | 27082 ChEBI | trehalose | + | builds acid from | from API 50CH acid |
| 68371 | 32528 ChEBI | turanose | - | builds acid from | from API 50CH acid |
| 68371 | 17151 ChEBI | xylitol | - | builds acid from | from API 50CH acid |
| @ref | Metabolite | Is sensitive | Is resistant | |
|---|---|---|---|---|
| 118834 | 0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate) |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68382 | acid phosphatase | + | 3.1.3.2 | from API zym |
| 118834 | alcohol dehydrogenase | - | 1.1.1.1 | |
| 68382 | alkaline phosphatase | + | 3.1.3.1 | from API zym |
| 68382 | alpha-chymotrypsin | - | 3.4.21.1 | from API zym |
| 68382 | alpha-fucosidase | - | 3.2.1.51 | from API zym |
| 68382 | alpha-galactosidase | - | 3.2.1.22 | from API zym |
| 68382 | alpha-glucosidase | + | 3.2.1.20 | from API zym |
| 68382 | alpha-mannosidase | - | 3.2.1.24 | from API zym |
| 118834 | amylase | - | ||
| 68382 | beta-galactosidase | - | 3.2.1.23 | from API zym |
| 118834 | beta-galactosidase | - | 3.2.1.23 | |
| 68382 | beta-glucosidase | + | 3.2.1.21 | from API zym |
| 68382 | beta-glucuronidase | - | 3.2.1.31 | from API zym |
| 118834 | caseinase | - | 3.4.21.50 | |
| 118834 | catalase | + | 1.11.1.6 | |
| 68382 | cystine arylamidase | - | 3.4.11.3 | from API zym |
| 118834 | DNase | - | ||
| 68382 | esterase (C 4) | + | from API zym | |
| 68382 | esterase lipase (C 8) | + | from API zym | |
| 118834 | gamma-glutamyltransferase | - | 2.3.2.2 | |
| 118834 | gelatinase | - | ||
| 118834 | lecithinase | - | ||
| 68382 | leucine arylamidase | + | 3.4.11.1 | from API zym |
| 118834 | lipase | - | ||
| 68382 | lipase (C 14) | - | from API zym | |
| 118834 | lysine decarboxylase | - | 4.1.1.18 | |
| 68382 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API zym |
| 68382 | naphthol-AS-BI-phosphohydrolase | + | from API zym | |
| 118834 | ornithine decarboxylase | - | 4.1.1.17 | |
| 118834 | oxidase | - | ||
| 118834 | phenylalanine ammonia-lyase | - | 4.3.1.24 | |
| 118834 | protease | - | ||
| 68382 | trypsin | - | 3.4.21.4 | from API zym |
| 118834 | tryptophan deaminase | - | ||
| 118834 | tween esterase | - | ||
| 118834 | urease | - | 3.5.1.5 | |
| 68382 | valine arylamidase | + | from API zym |
| @ref | ControlQ | GLY | ERY | DARA | LARA | RIB | DXYL | LXYL | ADO | MDX | GAL | GLU | FRU | MNE | SBE | RHA | DUL | INO | MAN | SOR | MDM | MDG | NAG | AMY | ARB | ESC | SAL | CEL | MAL | LAC | MEL | SAC | TRE | INU | MLZ | RAF | AMD | GLYG | XLT | GEN | TUR | LYX | TAG | DFUC | LFUC | DARL | LARL | GNT | 2KG | 5KG | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 118834 | not determinedn.d. | - | - | - | - | +/- | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | + | - | + | - | - | + | - | - | + | - | - | - | + | +/- | - | - | - | - | - | - | - | - | - | - | - | - |
Global distribution of 16S sequence GQ376180 (>99% sequence identity) for Nocardia from Microbeatlas ![]()
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | IMG accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|---|
| 66792 | ASM586322v1 assembly for Nocardia cyriacigeorgica DSM 44484 | contig | 135487 | 66.09 | ||||
| 67770 | ASM30855v1 assembly for Nocardia cyriacigeorgica NBRC 100375 | contig | 1206728 | 13.24 |
| @ref | Description | Accession | Length | Database | NCBI tax ID | |
|---|---|---|---|---|---|---|
| 20218 | Nocardia cyriacigeorgica strain DSM 44484 16S ribosomal RNA gene, complete sequence | AF430027 | 1494 | 135487 | ||
| 20218 | Nocardia cyriacigeorgica strain DSM 44484 16S ribosomal RNA gene, partial sequence | AY756550 | 606 | 135487 | ||
| 20218 | Nocardia cyriacigeorgica strain DSM 44484 16S ribosomal RNA gene, partial sequence | DQ659904 | 1404 | 135487 | ||
| 20218 | Nocardia cyriacigeorgica 16S ribosomal RNA gene, partial sequence | GQ376180 | 1441 | 135487 | ||
| 20218 | Nocardia cyriacigeorgica strain DSM 44484 16S ribosomal RNA gene, partial sequence | JN041560 | 462 | 135487 | ||
| 67770 | Nocardia cyriacigeorgici 16S ribosomal RNA gene, complete sequence | AF282889 | 1467 | 135487 | ||
| 124043 | Nocardia cyriacigeorgica strain DSM 44484 16S ribosomal RNA gene, partial sequence. | OP735353 | 1507 | 135487 |
| @ref | Trait | Model | Prediction | Confidence in % | In training data |
|---|---|---|---|---|---|
| 125439 | oxygen_tolerance | BacteriaNetⓘ | obligate aerobe | 99.40 | no |
| 125439 | gram_stain | BacteriaNetⓘ | positive | 99.00 | no |
| 125439 | motility | BacteriaNetⓘ | no | 86.60 | no |
| 125439 | spore_formation | BacteriaNetⓘ | yes | 77.50 | no |
| @ref | Trait | Model | Prediction | Confidence in % | In training data |
|---|---|---|---|---|---|
| 125438 | gram-positive | gram-positiveⓘ | yes | 92.90 | no |
| 125438 | anaerobic | anaerobicⓘ | no | 98.25 | yes |
| 125438 | spore-forming | spore-formingⓘ | yes | 61.46 | no |
| 125438 | aerobic | aerobicⓘ | yes | 90.40 | yes |
| 125438 | thermophilic | thermophileⓘ | no | 97.49 | yes |
| 125438 | flagellated | motile2+ⓘ | no | 91.00 | no |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Genetics | Genomic characteristics, virulence potential, antimicrobial resistance profiles, and phylogenetic insights into Nocardia cyriacigeorgica. | Yang C, Zheng YX, Gu HY, Chen H, Li W, Li F, Bi YW, Chen J, Wang FK, Sun QQ, Meng HB, Wu ZH, Yu S, Gu J, Cheng Y. | Ann Clin Microbiol Antimicrob | 10.1186/s12941-025-00791-x | 2025 | |
| Genetics | Metagenomic analysis reveals the roles of Actinobacteria in plasticizer-contaminated landfills and aids in identifying key degraders. | Rungsihiranrut A, Muangchinda C, Pinyakong O. | Sci Rep | 10.1038/s41598-025-03316-w | 2025 | |
| A CRISPR-Cas12a-Assisted Fluorescence Platform for Rapid and Accurate Detection of Nocardia cyriacigeorgica. | Liu X, Qiu X, Xu S, Che Y, Han L, Kang Y, Yue Y, Chen S, Li F, Li Z. | Front Cell Infect Microbiol | 10.3389/fcimb.2022.835213 | 2022 | ||
| Phylogeny | Efficient differentiation of Nocardia farcinica, Nocardia cyriacigeorgica and Nocardia beijingensis by high-resolution melting analysis using a novel locus. | Xu S, Hou X, Li D, Sun L, Li M, Ji X, Wang X, Li Z. | J Med Microbiol | 10.1099/jmm.0.001205 | 2020 | |
| Microbial risk assessment of Nocardia cyriacigeorgica in polluted environments, case of urban rainfall water. | Vautrin F, Pujic P, Paquet C, Bergeron E, Mouniee D, Marchal T, Salord H, Bonnet JM, Cournoyer B, Winiarski T, Louzier V, Rodriguez-Nava V. | Comput Struct Biotechnol J | 10.1016/j.csbj.2020.12.017 | 2021 | ||
| Molecular Characterization and Antimicrobial Susceptibilities of Nocardia Species Isolated from the Soil; A Comparison with Species Isolated from Humans. | Carrasco G, Monzon S, San Segundo M, Garcia E, Garrido N, Medina-Pascual MJ, Villalon P, Ramirez A, Jimenez P, Cuesta I, Valdezate S. | Microorganisms | 10.3390/microorganisms8060900 | 2020 | ||
| Pathogenicity | Imipenem-resistant Nocardia cyriacigeorgica infection in a child with chronic granulomatous disease. | Hagerman A, Rodriguez-Nava V, Boiron P, Crisinel PA, Posfay-Barbe KM. | J Clin Microbiol | 10.1128/jcm.02073-10 | 2011 | |
| Virulence test using nematodes to prescreen Nocardia species capable of inducing neurodegeneration and behavioral disorders. | Bernardin Souibgui C, Zoropogui A, Voisin J, Ribun S, Vasselon V, Pujic P, Rodriguez-Nava V, Belly P, Cournoyer B, Blaha D. | PeerJ | 10.7717/peerj.3823 | 2017 | ||
| Phylogeny | Nocardia veterana as a pathogen in North American patients. | Conville PS, Brown JM, Steigerwalt AG, Lee JW, Byrer DE, Anderson VL, Dorman SE, Holland SM, Cahill B, Carroll KC, Witebsky FG. | J Clin Microbiol | 10.1128/jcm.41.6.2560-2568.2003 | 2003 | |
| Telomerase RNA plays a major role in the completion of the life cycle in Ustilago maydis and shares conserved domains with other Ustilaginales. | Sanpedro-Luna JA, Jacinto-Vazquez JJ, Anastacio-Marcelino E, Posadas-Gutierrez CM, Olmos-Pineda I, Gonzalez-Bernal JA, Carcano-Montiel M, Vega-Alvarado L, Vazquez-Cruz C, Sanchez-Alonso P. | PLoS One | 10.1371/journal.pone.0281251 | 2023 | ||
| Nocardia cyriacigeorgica Elicits Gut Disturbances in a Leaky Gut Model of Colitis, but Not the Harmful Cascade Leading to Gut-First Parkinson's Disease. | Magalhaes JD, Candeias E, Melo-Marques I, Abreu AE, Pereira-Santos AR, Esteves AR, Cardoso SM, Empadinhas N. | Int J Mol Sci | 10.3390/ijms25063423 | 2024 | ||
| Genetics | The Nocardia cyriacigeorgica GUH-2 genome shows ongoing adaptation of an environmental Actinobacteria to a pathogen's lifestyle. | Zoropogui A, Pujic P, Normand P, Barbe V, Belli P, Graindorge A, Roche D, Vallenet D, Mangenot S, Boiron P, Rodriguez-Nava V, Ribun S, Richard Y, Cournoyer B, Blaha D. | BMC Genomics | 10.1186/1471-2164-14-286 | 2013 | |
| Genetics | Genome Sequences of Three Nocardia cyriacigeorgica Strains and One Nocardia asteroides Strain. | Vautrin F, Bergeron E, Dubost A, Abrouk D, Martin C, Cournoyer B, Louzier V, Winiarski T, Rodriguez-Nava V, Pujic P | Microbiol Resour Announc | 10.1128/MRA.00600-19 | 2019 | |
| Phylogeny | Nocardia cyriacigeorgici sp. nov.. | Yassin AF, Rainey FA, Steiner U | Int J Syst Evol Microbiol | 10.1099/00207713-51-4-1419 | 2001 |
| #11810 | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 44484 |
| #20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 ) |
| #20218 | Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 ) |
| #39919 | ; Curators of the CIP; |
| #58072 | Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 48295 |
| #66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) . |
| #67770 | Japan Collection of Microorganism (JCM) ; Curators of the JCM; |
| #68371 | Automatically annotated from API 50CH acid . |
| #68382 | Automatically annotated from API zym . |
| #69479 | João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta . |
| #118834 | Collection of Institut Pasteur ; Curators of the CIP; CIP 107669 |
| #124043 | Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy . |
| #125438 | Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 ) |
| #125439 | Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 . |
| #126262 | A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 ) |
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