Neisseria meningitidis (DSM 15465, Z2491)
Neisseria meningitidis Z2491 is a microaerophile bacterium that was isolated from cerebrospinal fluid.
microaerophile genome sequence BacteriaName and taxonomic classification
| @ref 20215 |
Last LPSN update
2026-05-29 08:27:20 |
| Domain Bacteria |
| Phylum Pseudomonadota |
| Class Betaproteobacteria |
| Order Neisseriales |
| Family Neisseriaceae |
| Genus Neisseria |
| Species Neisseria meningitidis |
| Full scientific name Neisseria meningitidis (Albrecht and Ghon 1901) Murray 1929 (Approved Lists 1980) |
| Synonyms (1) |
Culture and growth conditions
Culture medium
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 5940 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | Medium recipe at MediaDive  | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base |
Culture temp
| @ref | Growth | Type | Temperature (°C) | |
|---|---|---|---|---|
| 5940 | positive | growth | 37 |
Physiology and metabolism
Sequence information
Genome sequences
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | IMG accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|---|
| 66792 | ASM910v1 assembly for Neisseria meningitidis Z2491 | complete | GCA_000009105   | 122587.5  | 637000190  | 122587 | 98.86 |  |
Genome browser: GCA_000009105
Literature
Literature 
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Pathogenicity | Comparative sequence- and structure-inspired drug design for PilF protein of Neisseria meningitidis. | Mehta AS, Snigdha K, Potukuchi MS, Tsonis PA | Hum Genomics | 10.1186/s40246-015-0027-1 | 2015 | |
| Metabolism | Novel non-specific DNA adenine methyltransferases. | Drozdz M, Piekarowicz A, Bujnicki JM, Radlinska M | Nucleic Acids Res | 10.1093/nar/gkr1039 | 2011 | |
| Genetics | Genotypic and phenotypic modifications of Neisseria meningitidis after an accidental human passage. | Omer H, Rose G, Jolley KA, Frapy E, Zahar JR, Maiden MC, Bentley SD, Tinsley CR, Nassif X, Bille E | PLoS One | 10.1371/journal.pone.0017145 | 2011 | |
| Genetics | A novel interpretation of structural dot plots of genomes derived from the analysis of two strains of Neisseria meningitidis. | Cuff WR, Duvvuri VR, Liang B, Duvvuri B, Wu GE, Wu J, Tsang RS | Genomics Proteomics Bioinformatics | 10.1016/S1672-0229(10)60018-6 | 2010 | |
| Direct detection and serogroup characterization of Neisseria meningitidis from outbreak of meningococcal meningitis in Delhi. | Negi S, Grover S, Rautela S, Rawat D, Gupta S, Khare S, Lal S, Rai A | Iran J Microbiol | 2010 | | ||
| Enzymology | The structure of the L9 immunotype lipooligosaccharide from Neisseria meningitidis NMA Z2491. | Choudhury B, Kahler CM, Datta A, Stephens DS, Carlson RW | Carbohydr Res | 10.1016/j.carres.2008.08.026 | 2008 | |
| Enzymology | Cloning, gene expression and characterization of a novel bacterial NAD-dependent non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase from Neisseria meningitidis strain Z2491. | Fourrat L, Iddar A, Valverde F, Serrano A, Soukri A | Mol Cell Biochem | 10.1007/s11010-007-9545-z | 2007 | |
| Genetics | Bacterial repetitive extragenic palindromic sequences are DNA targets for Insertion Sequence elements. | Tobes R, Pareja E | BMC Genomics | 10.1186/1471-2164-7-62 | 2006 | |
| Genetics | An in vitro strategy for the selective isolation of anomalous DNA from prokaryotic genomes. | van Passel MW, Bart A, Waaijer RJ, Luyf AC, van Kampen AH, van der Ende A | Nucleic Acids Res | 10.1093/nar/gnh115 | 2004 | |
| Pathogenicity | The REP2 repeats of the genome of Neisseria meningitidis are associated with genes coordinately regulated during bacterial cell interaction. | Morelle S, Carbonnelle E, Nassif X | J Bacteriol | 10.1128/JB.185.8.2618-2627.2003 | 2003 | |
| Genetics | Genome analysis and strain comparison of correia repeats and correia repeat-enclosed elements in pathogenic Neisseria. | Liu SV, Saunders NJ, Jeffries A, Rest RF | J Bacteriol | 10.1128/JB.184.22.6163-6173.2002 | 2002 | |
| Metabolism | In vivo expression of Neisseria meningitidis proteins homologous to the Haemophilus influenzae Hap and Hia autotransporters. | van Ulsen P, van Alphen L, Hopman CT, van der Ende A, Tommassen J | FEMS Immunol Med Microbiol | 10.1111/j.1574-695X.2001.tb00534.x | 2001 | |
| Genetics | Whole-genome organization and functional properties of miniature DNA insertion sequences conserved in pathogenic Neisseriae. | Mazzone M, De Gregorio E, Lavitola A, Pagliarulo C, Alifano P, Di Nocera PP | Gene | 10.1016/s0378-1119(01)00725-9 | 2001 | |
| Genetics | Comparative whole-genome analyses reveal over 100 putative phase-variable genes in the pathogenic Neisseria spp. | Snyder LAS, Butcher SA, Saunders NJ | Microbiology (Reading) | 10.1099/00221287-147-8-2321 | 2001 | |
| Genetics | Short interrupted palindromes on the extragenic DNA of Escherichia coli K-12, Haemophilus influenzae and Neisseria meningitidis. | Vasconcelos AT, Maia MA, de Almeida DF | Bioinformatics | 10.1093/bioinformatics/16.11.968 | 2000 | |
| Genome sequencing and annotation. | Jeffries AC, Saunders NJ, Hood DW | Methods Mol Med | 10.1385/1-59259-149-3:215 | 2001 | | |
| Genetics | Finding pathogenicity islands and gene transfer events in genome data. | Lio P, Vannucci M | Bioinformatics | 10.1093/bioinformatics/16.10.932 | 2000 | |
| Enzymology | Genomic rearrangements in neisseria meningitidis strains of the ET-5 complex. | Froholm LO, Kolsto AB, Berner JM, Caugant DA | Curr Microbiol | 10.1007/s002840010073 | 2000 | |
| Genetics | Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491. | Parkhill J, Achtman M, James KD, Bentley SD, Churcher C, Klee SR, Morelli G, Basham D, Brown D, Chillingworth T, Davies RM, Davis P, Devlin K, Feltwell T, Hamlin N, Holroyd S, Jagels K, Leather S, Moule S, Mungall K, Quail MA, Rajandream MA, Rutherford KM, Simmonds M, Skelton J, Whitehead S, Spratt BG, Barrell BG | Nature | 10.1038/35006655 | 2000 | |
| Metabolism | Phosphorylcholine decoration of lipopolysaccharide differentiates commensal Neisseriae from pathogenic strains: identification of licA-type genes in commensal Neisseriae. | Serino L, Virji M | Mol Microbiol | 10.1046/j.1365-2958.2000.01825.x | 2000 | |
| Identification of regions of the chromosome of Neisseria meningitidis and Neisseria gonorrhoeae which are specific to the pathogenic Neisseria species. | Perrin A, Nassif X, Tinsley C | Infect Immun | 10.1128/IAI.67.11.6119-6129.1999 | 1999 | | |
| Enzymology | Analysis of the genetic differences between Neisseria meningitidis and Neisseria gonorrhoeae: two closely related bacteria expressing two different pathogenicities. | Tinsley CR, Nassif X | Proc Natl Acad Sci U S A | 10.1073/pnas.93.20.11109 | 1996 | |
| Enzymology | The physical map of the chromosome of a serogroup A strain of Neisseria meningitidis shows complex rearrangements relative to the chromosomes of the two mapped strains of the closely related species N. gonorrhoeae. | Dempsey JA, Wallace AB, Cannon JG | J Bacteriol | 10.1128/jb.177.22.6390-6400.1995 | 1995 | |
| Pathogenicity | Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18. | Bentley SD, Vernikos GS, Snyder LA, Churcher C, Arrowsmith C, Chillingworth T, Cronin A, Davis PH, Holroyd NE, Jagels K, Maddison M, Moule S, Rabbinowitsch E, Sharp S, Unwin L, Whitehead S, Quail MA, Achtman M, Barrell B, Saunders NJ, Parkhill J | PLoS Genet | 10.1371/journal.pgen.0030023 | 2006 | |
| Genetics | Comparative genomics of Neisseria meningitidis: core genome, islands of horizontal transfer and pathogen-specific genes. | Hotopp JCD, Grifantini R, Kumar N, Tzeng YL, Fouts D, Frigimelica E, Draghi M, Giuliani MM, Rappuoli R, Stephens DS, Grandi G, Tettelin H | Microbiology (Reading) | 10.1099/mic.0.29261-0 | 2006 | |
| Phylogeny | Use of a multilocus variable-number tandem repeat analysis method for molecular subtyping and phylogenetic analysis of Neisseria meningitidis isolates. | Liao JC, Li CC, Chiou CS | BMC Microbiol | 10.1186/1471-2180-6-44 | 2006 | |
| Pathogenicity | Characterization of MspA, an immunogenic autotransporter protein that mediates adhesion to epithelial and endothelial cells in Neisseria meningitidis. | Turner DP, Marietou AG, Johnston L, Ho KK, Rogers AJ, Wooldridge KG, Ala'Aldeen DA | Infect Immun | 10.1128/IAI.74.5.2957-2964.2006 | 2006 | |
| Genetics | Identification of pathogen-specific genes through microarray analysis of pathogenic and commensal Neisseria species. | Stabler RA, Marsden GL, Witney AA, Li Y, Bentley SD, Tang CM, Hinds J | Microbiology (Reading) | 10.1099/mic.0.28099-0 | 2005 | |
| Metabolism | Genetic characterization of pilin glycosylation and phase variation in Neisseria meningitidis. | Power PM, Roddam LF, Rutter K, Fitzpatrick SZ, Srikhanta YN, Jennings MP | Mol Microbiol | 10.1046/j.1365-2958.2003.03602.x | 2003 | |
How to cite
If you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive10475.20260601.11
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain dataIsabel Schober, Julia Koblitz, Joaquim Sardà Carbasse, Christian Ebeling, Marvin Leon Schmidt, Adam Podstawka, Rohit Gupta, Vinodh Ilangovan, Javad Chamanara, Jörg Overmann, Lorenz Christian Reimer
Nucleic Acids Research; database issue 2025.
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