Strain identifier
BacDive ID: 8439
Type strain: 
Species: Mycobacterium avium subsp. paratuberculosis
Strain history: CIP <- 1994, ATCC <- R.S. Merkal: strain 5617, Mycobacterium paratuberculosis <- D. Porter: strain TMC 807
NCBI tax ID(s): 1074454 (strain), 1770 (subspecies)
version 8.1 (current version)
General
@ref: 11514
BacDive-ID: 8439
DSM-Number: 44133
keywords: genome sequence, 16S sequence, Bacteria, microaerophile, mesophilic, Gram-positive, rod-shaped, human pathogen
description: Mycobacterium avium subsp. paratuberculosis DSM 44133 is a microaerophile, mesophilic, Gram-positive human pathogen that was isolated from feces of cow with naturally aquired paratuberculosis.
NCBI tax id
| NCBI tax id | Matching level |
|---|---|
| 1074454 | strain |
| 1770 | subspecies |
strain history
| @ref | history |
|---|---|
| 11514 | <- U. Jark, Tierärztl. Hochschule Hannover <- R. S. Merkal, 5617 (Mycobacterium paratuberculosis) <- D. Porter, TMC |
| 116671 | CIP <- 1994, ATCC <- R.S. Merkal: strain 5617, Mycobacterium paratuberculosis <- D. Porter: strain TMC 807 |
doi: 10.13145/bacdive8439.20230509.8.1
Name and taxonomic classification
LPSN
- @ref: 20215
- description: domain/bacteria
- keyword: phylum/actinomycetota
- domain: Bacteria
- phylum: Actinomycetota
- class: Actinomycetes
- order: Mycobacteriales
- family: Mycobacteriaceae
- genus: Mycobacterium
- species: Mycobacterium avium subsp. paratuberculosis
- full scientific name: Mycobacterium avium subsp. paratuberculosis (Bergey et al. 1923) Thorel et al. 1990
synonyms
- @ref: 20215
- synonym: Mycobacterium paratuberculosis
@ref: 11514
domain: Bacteria
phylum: Actinobacteria
class: Actinobacteria
order: Actinomycetales
family: Mycobacteriaceae
genus: Mycobacterium
species: Mycobacterium avium subsp. paratuberculosis
full scientific name: Mycobacterium avium subsp. paratuberculosis (Bergey et al. 1923) Thorel et al. 1990
type strain: yes
Morphology
cell morphology
- @ref: 116671
- gram stain: positive
- cell shape: rod-shaped
- motility: no
colony morphology
- @ref: 60601
- incubation period: 30 days
multimedia
| @ref | multimedia content | intellectual property rights | caption |
|---|---|---|---|
| 11514 | https://www.dsmz.de/microorganisms/photos/DSM_44133-1.jpg | © Leibniz-Institut DSMZ | |
| 11514 | https://www.dsmz.de/microorganisms/photos/DSM_44133.jpg | © Leibniz-Institut DSMZ | Medium 780 37°C |
Culture and growth conditions
culture medium
| @ref | name | growth | link | composition |
|---|---|---|---|---|
| 11514 | MIDDLEBROOK MEDIUM WITH MYCOBACTIN (DSMZ Medium 780) | yes | https://mediadive.dsmz.de/medium/780 | Name: MIDDLEBROOK MEDIUM WITH MYCOBACTIN (DSMZ Medium 780) Composition: Bacto Middlebrook 7H10 agar 20.9945 g/l Mycobactine J 0.002 g/l Absolute ethanol Glycerol Distilled water |
| 40896 | MEDIUM 72- for trypto casein soja agar | yes | Distilled water make up to (1000.000 ml);Trypto casein soy agar (40.000 g) | |
| 116671 | CIP Medium 96 | yes | https://catalogue-crbip.pasteur.fr/fiche_milieu.xhtml?crbip=96 | |
| 116671 | CIP Medium 72 | yes | https://catalogue-crbip.pasteur.fr/fiche_milieu.xhtml?crbip=72 |
culture temp
| @ref | growth | type | temperature | range |
|---|---|---|---|---|
| 11514 | positive | growth | 37 | mesophilic |
| 40896 | positive | growth | 37 | mesophilic |
| 60601 | positive | growth | 37 | mesophilic |
| 116671 | positive | growth | 37 | mesophilic |
Physiology and metabolism
oxygen tolerance
- @ref: 60601
- oxygen tolerance: microaerophile
metabolite utilization
| @ref | Chebi-ID | metabolite | utilization activity | kind of utilization tested |
|---|---|---|---|---|
| 116671 | 17632 | nitrate | - | reduction |
| 116671 | 16301 | nitrite | - | reduction |
metabolite production
- @ref: 116671
- Chebi-ID: 35581
- metabolite: indole
- production: no
enzymes
| @ref | value | activity | ec |
|---|---|---|---|
| 116671 | oxidase | - | |
| 116671 | catalase | + | 1.11.1.6 |
| 116671 | urease | - | 3.5.1.5 |
| 68382 | alkaline phosphatase | + | 3.1.3.1 |
| 68382 | esterase (C 4) | + | |
| 68382 | esterase lipase (C 8) | + | |
| 68382 | lipase (C 14) | - | |
| 68382 | leucine arylamidase | + | 3.4.11.1 |
| 68382 | valine arylamidase | - | |
| 68382 | cystine arylamidase | - | 3.4.11.3 |
| 68382 | trypsin | - | 3.4.21.4 |
| 68382 | alpha-chymotrypsin | - | 3.4.21.1 |
| 68382 | acid phosphatase | + | 3.1.3.2 |
| 68382 | naphthol-AS-BI-phosphohydrolase | - | |
| 68382 | alpha-galactosidase | - | 3.2.1.22 |
| 68382 | beta-galactosidase | - | 3.2.1.23 |
| 68382 | beta-glucuronidase | - | 3.2.1.31 |
| 68382 | alpha-glucosidase | + | 3.2.1.20 |
| 68382 | beta-glucosidase | - | 3.2.1.21 |
| 68382 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 |
| 68382 | alpha-mannosidase | - | 3.2.1.24 |
| 68382 | alpha-fucosidase | - | 3.2.1.51 |
API zym
| @ref | Control | Alkaline phosphatase | Esterase | Esterase Lipase | Lipase | Leucine arylamidase | Valine arylamidase | Cystine arylamidase | Trypsin | alpha- Chymotrypsin | Acid phosphatase | Naphthol-AS-BI-phosphohydrolase | alpha- Galactosidase | beta- Galactosidase | beta- Glucuronidase | alpha- Glucosidase | beta- Glucosidase | N-acetyl-beta- glucosaminidase | alpha- Mannosidase | alpha- Fucosidase |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 116671 | - | + | + | + | - | + | - | - | - | - | + | - | - | - | - | + | - | - | - | - |
Isolation, sampling and environmental information
isolation
| @ref | sample type | country | origin.country | continent | sampling date | geographic location | isolation date |
|---|---|---|---|---|---|---|---|
| 11514 | feces of cow with naturally aquired paratuberculosis | USA | USA | North America | |||
| 60601 | Cow feces,naturally aquired paratuberculos | USA | USA | North America | 1966 | Iowa | |
| 116671 | Animal, Cow, feces | United States of America | USA | North America | Ames, Iowa | 1966 |
isolation source categories
| Cat1 | Cat2 | Cat3 |
|---|---|---|
| #Infection | #Disease | |
| #Host | #Mammals | #Bovinae (Cow, Cattle) |
| #Host Body Product | #Gastrointestinal tract | #Feces (Stool) |
taxonmaps
- @ref: 69479
- File name: preview.99_402.png
- url: https://microbeatlas.org/index.html?action=taxon&taxon_id=90_10;96_37;97_39;98_43;99_402&stattab=map
- Last taxonomy: Mycobacterium
- 16S sequence: X52934
- Sequence Identity:
- Total samples: 24078
- soil counts: 12779
- aquatic counts: 4789
- animal counts: 3677
- plant counts: 2833
Safety information
risk assessment
| @ref | pathogenicity human | pathogenicity animal | biosafety level | biosafety level comment |
|---|---|---|---|---|
| 11514 | yes | yes | 2 | Risk group (German classification) |
| 116671 | 2 | Risk group (French classification) |
Sequence information
16S sequences
| @ref | description | accession | length | database | NCBI tax ID |
|---|---|---|---|---|---|
| 20218 | Mycobacterium avium subsp. paratuberculosis strain ATCC 19698 16S ribosomal RNA gene and 16S-23S ribosomal RNA intergenic spacer, partial sequence | EF521900 | 438 | ena | 1770 |
| 20218 | M.paratuberculosis 16S ribosomal RNA gene | M59265 | 145 | ena | 1770 |
| 20218 | Mycobacterium paratuberculosis 16S rRNA gene | X52934 | 1463 | ena | 1770 |
| 20218 | Mycobacterium avium subsp. paratuberculosis strain CIP 103963 16S ribosomal RNA gene, partial sequence | AF547899 | 554 | ena | 1770 |
| 20218 | Mycobacterium avium subsp. paratuberculosis strain DSM 44133 16S ribosomal RNA gene, partial sequence | HM007575 | 595 | ena | 1770 |
| 11514 | Mycobacterium avium subsp. paratuberculosis strain ATCC 19698 16S ribosomal RNA gene, partial sequence | EF521896 | 1442 | ena | 1770 |
Genome sequences
| @ref | description | accession | assembly level | database | NCBI tax ID |
|---|---|---|---|---|---|
| 66792 | Mycobacterium avium subsp. paratuberculosis ATCC 19698 | 1074454.6 | wgs | patric | 1074454 |
| 66792 | Mycobacterium avium paratuberculosis ATCC 19698 | 2548876531 | draft | img | 1074454 |
Genome-based predictions
predictions
| trait | prediction | confidence | training_data |
|---|---|---|---|
| motile | no | 95.329 | no |
| flagellated | no | 98.872 | no |
| gram-positive | yes | 90.117 | no |
| anaerobic | no | 99.548 | no |
| aerobic | yes | 91.382 | yes |
| halophile | no | 92.986 | no |
| spore-forming | no | 85.72 | no |
| thermophile | no | 97.386 | no |
| glucose-util | yes | 63.486 | no |
| glucose-ferment | no | 92.844 | no |
External links
@ref: 11514
culture collection no.: DSM 44133, ATCC 19698, TMC 807, CCUG 55483, CIP 103963
straininfo link
- @ref: 77838
- straininfo: 44555
literature
| topic | Pubmed-ID | title | authors | journal | DOI | year | mesh | topic2 |
|---|---|---|---|---|---|---|---|---|
| Pathogenicity | 2088185 | Effects of colonial morphology and tween 80 on antimicrobial susceptibility of Mycobacterium paratuberculosis. | Van Boxtel RM, Lambrecht RS, Collins MT | Antimicrob Agents Chemother | 10.1128/AAC.34.12.2300 | 1990 | Anti-Bacterial Agents/pharmacology, Microbial Sensitivity Tests, Mycobacterium/*drug effects/growth & development, Polysorbates/*pharmacology | |
| Metabolism | 2379110 | Granulomatous enteritis following oral inoculation of newborn rabbits with Mycobacterium paratuberculosis of bovine origin. | Mokresh AH, Butler DG | Can J Vet Res | 1990 | Animals, Animals, Newborn, Cattle, *Disease Models, Animal, Enteritis/metabolism/microbiology/pathology/*veterinary, Feces/microbiology, Granuloma/metabolism/microbiology/pathology/*veterinary, Ileum/metabolism, Intestines/microbiology/pathology, Membrane Potentials, Mycobacterium/isolation & purification, Paratuberculosis/metabolism/microbiology/*pathology, *Rabbits | Enzymology | |
| Phylogeny | 2503996 | Genetic relatedness among Mycobacterium paratuberculosis and M. avium complex. | Labidi A, Thoen CO | Acta Leprol | 1989 | DNA Probes, DNA, Bacterial/genetics/isolation & purification, Genes, Bacterial, Mycobacterium/*genetics, Mycobacterium avium Complex/*genetics, Paratuberculosis/microbiology, Species Specificity | Enzymology | |
| Enzymology | 2784928 | Analysis of restriction endonuclease fragment patterns of DNA from Mycobacterium paratuberculosis. | Whipple DL, Kapke PA, Andrews RE Jr | Vet Microbiol | 10.1016/0378-1135(89)90084-9 | 1989 | Animals, Cattle, DNA, Bacterial/*analysis, Deoxyribonucleases, Type II Site-Specific, Electrophoresis, Agar Gel, Goats, Mycobacterium/*genetics, Paratuberculosis/microbiology, Restriction Mapping, Sheep | |
| 2807547 | A rabbit model for study of Mycobacterium paratuberculosis infection. | Mokresh AH, Czuprynski CJ, Butler DG | Infect Immun | 10.1128/iai.57.12.3798-3807.1989 | 1989 | Animals, Diarrhea/microbiology, Feces/microbiology, Female, Granuloma/pathology, Intestines/pathology, Lactation, Mycobacterium/*pathogenicity, Paratuberculosis/microbiology/pathology/*physiopathology/transmission, Pregnancy, Rabbits | ||
| Enzymology | 2854962 | Characterization of total deoxyribonucleic acid of Mycobacterium paratuberculosis (ATCC 19698) and of M. avium complex (ATCC 25291) using restriction enzymes. | Labidi A | Arch Inst Pasteur Tunis | 1988 | Animals, *DNA Restriction Enzymes, DNA, Bacterial/*analysis, Electrophoresis, Agar Gel, Mycobacterium/*analysis, Mycobacterium avium Complex/*analysis, Paratuberculosis/microbiology | ||
| Enzymology | 8056872 | Histopathological and morphometrical comparison of granulomatous lesions in BALB/c and C3H/HeJ mice inoculated with Mycobacterium paratuberculosis. | Tanaka S, Sato M, Taniguchi T, Yokomizo Y | J Comp Pathol | 10.1016/s0021-9975(08)80315-5 | 1994 | Animals, Female, Granuloma/microbiology/*pathology, Intestines/microbiology/pathology, Liver/microbiology/*pathology, Macrophages/microbiology, Mice, Mice, Inbred BALB C, Mice, Inbred C3H, Mycobacterium avium subsp. paratuberculosis/*isolation & purification, Paratuberculosis/microbiology/*pathology, Spleen/microbiology/*pathology | Phylogeny |
| Enzymology | 8729083 | Relationship of acid phosphatase activity to ultrastructural features in mice inoculated with Mycobacterium paratuberculosis. | Tanaka S, Sato M, Taniguchi T, Yokomizo Y | J Comp Pathol | 10.1016/s0021-9975(96)80065-x | 1996 | Acid Phosphatase/*metabolism/ultrastructure, Animals, Enzyme Activation, Liver/enzymology/ultrastructure, Mice, Mice, Inbred BALB C, Mice, Inbred C3H, *Mycobacterium avium subsp. paratuberculosis, Paratuberculosis/*enzymology/*pathology, Spleen/enzymology/ultrastructure | Metabolism |
| Stress | 9501439 | Thermal tolerance of Mycobacterium paratuberculosis. | Sung N, Collins MT | Appl Environ Microbiol | 10.1128/AEM.64.3.999-1005.1998 | 1998 | Animals, Cattle, *Hot Temperature, Humans, Milk/microbiology, Mycobacterium avium subsp. paratuberculosis/*physiology, Regression Analysis | Pathogenicity |
| Pathogenicity | 10189195 | HPLC does not differentiate Mycobacterium paratuberculosis from Mycobacterium avium. | Dei R, Tortoli E, Bartoloni A, Simonetti MT, Lillini E | Vet Microbiol | 10.1016/s0378-1135(98)00292-2 | 1999 | Animals, Cattle, Cattle Diseases/diagnosis/*microbiology, Chromatography, High Pressure Liquid/veterinary, Diagnosis, Differential, Humans, Mycobacterium avium/chemistry/*classification, Mycobacterium avium subsp. paratuberculosis/chemistry/*classification, Mycolic Acids/analysis, Paratuberculosis/*diagnosis, Tuberculosis/diagnosis/*veterinary | Phylogeny |
| Cultivation | 10742208 | Effect of three factors in cheese production (pH, salt, and heat) on Mycobacterium avium subsp. paratuberculosis viability. | Sung N, Collins MT | Appl Environ Microbiol | 10.1128/AEM.66.4.1334-1339.2000 | 2000 | Cheese/*microbiology, Colony Count, Microbial, Culture Media, *Hot Temperature, Hydrogen-Ion Concentration, Mycobacterium avium subsp. paratuberculosis/*growth & development, Sodium Chloride/*pharmacology | Stress |
| 11055864 | Reduced formation of granulomata in gamma(delta) T cell knockout BALB/c mice inoculated with Mycobacterium avium subsp. paratuberculosis. | Tanaka S, Itohara S, Sato M, Taniguchi T, Yokomizo Y | Vet Pathol | 10.1354/vp.37-5-415 | 2000 | Animals, Female, Granuloma/pathology/*veterinary, Intestine, Small/microbiology/pathology, Liver/microbiology/pathology, Mice, Mice, Inbred BALB C, Mice, Knockout, *Mycobacterium avium subsp. paratuberculosis/growth & development/immunology, Paratuberculosis/immunology/microbiology/*pathology, Receptors, Antigen, T-Cell, gamma-delta/genetics/immunology/*physiology, Rodent Diseases/immunology/microbiology/*pathology, Spleen/microbiology/pathology | ||
| Cultivation | 11525992 | Effect of turbulent-flow pasteurization on survival of Mycobacterium avium subsp. paratuberculosis added to raw milk. | Pearce LE, Truong HT, Crawford RA, Yates GF, Cavaignac S, de Lisle GW | Appl Environ Microbiol | 10.1128/AEM.67.9.3964-3969.2001 | 2001 | Animals, Cattle, Culture Media, *Hot Temperature, Humans, Milk/*microbiology, Mycobacterium avium subsp. paratuberculosis/*growth & development/isolation & purification | Stress |
| 11939333 | Development and application of quantitative polymerase chain reaction assay based on the ABI 7700 system (TaqMan) for detection and quantification of Mycobacterium avium subsp. paratuberculosis. | Kim SG, Shin SJ, Jacobson RH, Miller LJ, Harpending PR, Stehman SM, Rossiter CA, Lein DA | J Vet Diagn Invest | 10.1177/104063870201400206 | 2002 | Animals, Cattle, Cattle Diseases/*diagnosis/genetics, DNA, Bacterial/analysis, Feces/microbiology, Mycobacterium avium subsp. paratuberculosis/*genetics/*pathogenicity, Paratuberculosis/*diagnosis/genetics, Polymerase Chain Reaction/methods/*veterinary, Sensitivity and Specificity | ||
| Enzymology | 15297504 | Amplified fragment length polymorphism reveals genomic variability among Mycobacterium avium subsp. paratuberculosis isolates. | O'Shea B, Khare S, Bliss K, Klein P, Ficht TA, Adams LG, Rice-Ficht AC | J Clin Microbiol | 10.1128/JCM.42.8.3600-3606.2004 | 2004 | Base Sequence, DNA Primers, DNA, Bacterial/genetics/isolation & purification, Gene Amplification, Genetic Variation, Humans, Mycobacterium avium/*genetics/isolation & purification, Mycobacterium avium subsp. paratuberculosis/*genetics/isolation & purification, *Polymorphism, Genetic, Restriction Mapping | Phylogeny |
| Phylogeny | 15927290 | Real-time quantitative PCR detection of Mycobacterium avium subsp. paratuberculosis and differentiation from other mycobacteria using SYBR Green and TaqMan assays. | Ravva SV, Stanker LH | J Microbiol Methods | 10.1016/j.mimet.2005.04.004 | 2005 | Animals, Bacteriological Techniques, Base Sequence, Benzothiazoles, Cattle, DNA, Bacterial/*analysis/*genetics, Diamines, Fluorescent Dyes, Mycobacterium/genetics/isolation & purification, Mycobacterium avium subsp. paratuberculosis/*genetics/*isolation & purification, Organic Chemicals, Paratuberculosis/microbiology, Polymerase Chain Reaction/*methods/statistics & numerical data, Quinolines, Sensitivity and Specificity, Species Specificity | Enzymology |
| Metabolism | 16368974 | Members of the 30- to 32-kilodalton mycolyl transferase family (Ag85) from culture filtrate of Mycobacterium avium subsp. paratuberculosis are immunodominant Th1-type antigens recognized early upon infection in mice and cattle. | Rosseels V, Marche S, Roupie V, Govaerts M, Godfroid J, Walravens K, Huygen K | Infect Immun | 10.1128/IAI.74.1.202-212.2006 | 2006 | Acyltransferases/*immunology/metabolism, Animals, Antigens, Bacterial/*immunology/metabolism, Cattle, Cell Proliferation, Cells, Cultured, Immunodominant Epitopes/*immunology/metabolism, Interferon-gamma/biosynthesis, Lymphocyte Activation/immunology, Male, Mice, Mice, Inbred C57BL, Mice, Mutant Strains, Molecular Weight, Mycobacterium avium subsp. paratuberculosis/*growth & development/*immunology/metabolism, Paratuberculosis/*immunology/metabolism/microbiology, Th1 Cells/*immunology/pathology | |
| Enzymology | 16751566 | Inactivation of Mycobacterium avium subsp. paratuberculosis in cow's milk by means of high hydrostatic pressure at mild temperatures. | Lopez-Pedemonte T, Sevilla I, Garrido JM, Aduriz G, Guamis B, Juste RA, Roig-Sagues AX | Appl Environ Microbiol | 10.1128/AEM.01924-05 | 2006 | Animals, Cattle, Female, Hydrostatic Pressure, Milk/*microbiology, Mycobacterium avium/*isolation & purification, Mycobacterium avium subsp. paratuberculosis/*isolation & purification, Thermodynamics | Phylogeny |
| Pathogenicity | 16839422 | Interaction between Mycobacterium avium subsp. paratuberculosis and environmental protozoa. | Whan L, Grant IR, Rowe MT | BMC Microbiol | 10.1186/1471-2180-6-63 | 2006 | Acanthamoeba/growth & development/*microbiology, Acanthamoeba castellanii/growth & development/*microbiology, Animals, Chlorine/*pharmacology, Coculture Techniques, *Drug Resistance, Bacterial, Microscopy, Electron, Mycobacterium avium subsp. paratuberculosis/*drug effects/*growth & development, Water/parasitology, Water Microbiology | |
| Enzymology | 17106226 | Analysis of the seroprevalence of bovine paratuberculosis and the application of modified absorbed ELISA to field sample testing in Korea. | Park KT, Ahn J, Davis WC, Koo HC, Kwon NH, Jung WK, Kim JM, Hong SK, Park YH | J Vet Sci | 10.4142/jvs.2006.7.4.349 | 2006 | Animals, Antibodies, Bacterial/blood, Cattle, Cattle Diseases/*epidemiology/*microbiology, Enzyme-Linked Immunosorbent Assay/veterinary, Female, Korea/epidemiology, Male, Mycobacterium avium subsp. paratuberculosis/*isolation & purification, Paratuberculosis/blood/*epidemiology, ROC Curve, Sensitivity and Specificity, Seroepidemiologic Studies | Phylogeny |
| Pathogenicity | 20547041 | Comparison of the activities of the lantibiotics nisin and lacticin 3147 against clinically significant mycobacteria. | Carroll J, Draper LA, O'Connor PM, Coffey A, Hill C, Ross RP, Cotter PD, O'Mahony J | Int J Antimicrob Agents | 10.1016/j.ijantimicag.2010.03.029 | 2010 | Anti-Bacterial Agents/*pharmacology, Bacteriocins/*pharmacology, Humans, Microbial Sensitivity Tests, Mycobacterium avium subsp. paratuberculosis/*drug effects, Mycobacterium kansasii/*drug effects, Mycobacterium tuberculosis/*drug effects, Nisin/*pharmacology | |
| Biotechnology | 21381400 | [Study on the effects of HTST pasteurization temperatures on Mycobacterium avium subsp. paratuberculosis in an industrial fluid milk-processing system]. | Igimi S, Iriguchi S, Monden S, Okada Y, Yamamoto S, Mori Y | Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku | 2010 | Animals, *Dairy Products, *Food Handling, *Food Microbiology, Food-Processing Industry, Humans, Milk/*microbiology, *Mycobacterium avium subsp. paratuberculosis, *Sterilization, *Temperature | Pathogenicity | |
| Pathogenicity | 21468208 | Gene encoded antimicrobial peptides, a template for the design of novel anti-mycobacterial drugs. | Carroll J, Field D, O'Connor PM, Cotter PD, Coffey A, Hill C, Ross RP, O'Mahony J | Bioeng Bugs | 10.4161/bbug.1.6.13642 | 2010 | Anti-Bacterial Agents/*pharmacology, Genetic Variation/*genetics, Humans, Indicators and Reagents, Microbial Sensitivity Tests/methods, Mycobacterium/classification/*drug effects, Mycobacterium avium subsp. paratuberculosis/*drug effects, Mycobacterium tuberculosis/*drug effects, Nisin/chemistry/genetics/*pharmacology, Oxazines, Protein Engineering, Xanthenes | Phylogeny |
| Genetics | 21555192 | Divergent cytokine responses of macrophages to Mycobacterium avium subsp. paratuberculosis strains of Types II and III in a standardized in vitro model. | Borrmann E, Mobius P, Diller R, Kohler H | Vet Microbiol | 10.1016/j.vetmic.2011.04.002 | 2011 | Bacterial Typing Techniques, Cell Line, Genotype, Humans, Interleukin-10/*immunology, Interleukin-1beta/*immunology, Macrophages/*immunology, Mycobacterium avium subsp. paratuberculosis/classification/genetics/*pathogenicity, Paratuberculosis/*immunology/microbiology, Polymerase Chain Reaction, Polymorphism, Restriction Fragment Length, RNA, Messenger/metabolism, Reverse Transcriptase Polymerase Chain Reaction, Tumor Necrosis Factor-alpha/*immunology | Pathogenicity |
| Genetics | 24095568 | Stability of genotyping target sequences of Mycobacterium avium subsp. paratuberculosis upon cultivation on different media, in vitro- and in vivo passage, and natural infection. | Kasnitz N, Kohler H, Weigoldt M, Gerlach GF, Mobius P | Vet Microbiol | 10.1016/j.vetmic.2013.09.008 | 2013 | Animals, Cattle, Cattle Diseases/*microbiology, DNA, Bacterial/genetics, *Genomic Instability, Genotype, Minisatellite Repeats/genetics, Mycobacterium avium subsp. paratuberculosis/*genetics/*growth & development, Paratuberculosis/*microbiology, Polymorphism, Restriction Fragment Length/genetics, Reproducibility of Results | Cultivation |
| Enzymology | 31002199 | Development and validation of a loop-mediated isothermal amplification assay-a rapid and sensitive detection tool for Mycobacterium avium subsp. paratuberculosis in small ruminants. | Sange MD, Becker A, Hassan AA, Bulte M, Ganter M, Siebert U, Abdulmawjood A | J Appl Microbiol | 10.1111/jam.14284 | 2019 | Animals, Biological Assay, Feces/microbiology, Goats/microbiology, Limit of Detection, Milk/microbiology, Mycobacterium avium subsp. paratuberculosis/*genetics/*isolation & purification, Nucleic Acid Amplification Techniques/*methods/*standards, Paratuberculosis/*diagnosis/*microbiology, Real-Time Polymerase Chain Reaction, Ruminants/*microbiology, Sheep/microbiology | Phylogeny |
Reference
| @id | authors | catalogue | doi/url | title | journal | pubmed |
|---|---|---|---|---|---|---|
| 11514 | Curators of the DSMZ | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 44133) | https://www.dsmz.de/collection/catalogue/details/culture/DSM-44133 | |||
| 20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M. | 10.1099/ijsem.0.004332 | List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ | |||
| 20218 | Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P. | 10.1016/j.syapm.2013.11.002 | StrainInfo introduces electronic passports for microorganisms. | Syst Appl Microbiol. 37: 42-50 2014 | 24321274 | |
| 40896 | Curators of the CIP | https://brclims.pasteur.fr/brcWeb/souche/detail/1/15818 | ||||
| 60601 | Curators of the CCUG | Culture Collection University of Gothenburg (CCUG) (CCUG 55483) | https://www.ccug.se/strain?id=55483 | |||
| 66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | https://diaspora-project.de/progress.html#genomes | Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | |||
| 68382 | Automatically annotated from API zym | |||||
| 69479 | João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich. | https://microbeatlas.org/ | MicrobeAtlas 1.0 beta | |||
| 77838 | Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J. | 10.60712/SI-ID44555.1 | StrainInfo: A central database for resolving microbial strain identifiers | |||
| 116671 | Curators of the CIP | Collection of Institut Pasteur (CIP 103963) | https://catalogue-crbip.pasteur.fr/fiche_catalogue.xhtml?crbip=CIP%20103963 |