Archive BacDiveID:10.13145/bacdive6559.20230509.8.1

Strain identifier

BacDive ID: 6559

Type strain:

Species: Lacticaseibacillus casei

Strain Designation: 03, 7, O3

Strain history: CIP <- 1998, DSM, <- ATCC <- G. J. Hucker: strain O3 <- S. Orla-Jensen: strain 7, Streptobacterium casei

NCBI tax ID(s): 1582 (species)

For citation purpose refer to the digital object identifier (doi) of the current version.

General

@ref: 8425

BacDive-ID: 6559

DSM-Number: 20011

keywords: genome sequence, 16S sequence, Bacteria, facultative anaerobe, human pathogen

description: Lacticaseibacillus casei 03 is a facultative anaerobe human pathogen that was isolated from cheese.

NCBI tax id

NCBI tax id: 1582
Matching level: species

strain history

@ref	history
8425	<- ATCC <- G.J. Hucker, 03 <- S. Orla-Jensen, 7 (Streptobacterium casei)
67770	ATCC 393 <-- G. J. Hucker 03 <-- S. Orla-Jensen 7 ("Streptobacterium casei").
117199	CIP <- 1998, DSM, <- ATCC <- G. J. Hucker: strain O3 <- S. Orla-Jensen: strain 7, Streptobacterium casei

doi: 10.13145/bacdive6559.20230509.8.1

Name and taxonomic classification

LPSN

@ref: 20215
description: domain/bacteria
keyword: phylum/bacillota
domain: Bacteria
phylum: Bacillota
class: Bacilli
order: Lactobacillales
family: Lactobacillaceae
genus: Lacticaseibacillus
species: Lacticaseibacillus casei
full scientific name: Lacticaseibacillus casei (Orla-Jensen 1916) Zheng et al. 2020
synonyms
@ref synonym
20215 Lactobacillus casei
20215 Caseobacterium vulgare

@ref	synonym
20215	Lactobacillus casei
20215	Caseobacterium vulgare

@ref: 8425

domain: Bacteria

phylum: Firmicutes

class: Bacilli

order: Lactobacillales

family: Lactobacillaceae

genus: Lacticaseibacillus

species: Lacticaseibacillus casei

full scientific name: Lacticaseibacillus casei (Orla-Jensen 1916) Zheng et al. 2020

strain designation: 03, 7, O3

type strain: yes

Morphology

cell morphology

@ref	motility	confidence	gram stain	cell shape
69480	no	96.635
69480		100	positive
117199	no		positive	rod-shaped

Culture and growth conditions

culture medium

@ref	name	growth	link	composition
8425	MRS MEDIUM (DSMZ Medium 11)	yes	https://mediadive.dsmz.de/medium/11	Name: MRS MEDIUM (DSMZ Medium 11) Composition: Glucose 20.0 g/l Casein peptone 10.0 g/l Meat extract 10.0 g/l Na-acetate 5.0 g/l Yeast extract 5.0 g/l (NH4)3 citrate 2.0 g/l K2HPO4 2.0 g/l Tween 80 1.0 g/l MgSO4 x 7 H2O 0.2 g/l MnSO4 x H2O 0.05 g/l Distilled water
41833	MEDIUM 40- for Lactobacillus and Leuconostoc	yes		Distilled water make up to (1000.000 ml);Man Rogosa Sharp agar (68.000 g)
117199	CIP Medium 40	yes	https://catalogue-crbip.pasteur.fr/fiche_milieu.xhtml?crbip=40

culture temp

@ref	growth	type	temperature	range
22930	positive	growth	15-45
8425	positive	growth	30	mesophilic
41833	positive	growth	37	mesophilic
67770	positive	growth	37	mesophilic
117199	positive	growth	15-45
117199	no	growth	10	psychrophilic

Physiology and metabolism

oxygen tolerance

@ref: 117199
oxygen tolerance: facultative anaerobe

spore formation

@ref	spore formation	confidence
69481	no	100
69480	no	99.99
117199	no

compound production

@ref	compound
8425	acetoin
8425	diacetyl

murein

@ref: 8425
murein short key: A11.31
type: A4alpha L-Lys-D-Asp

metabolite utilization

@ref	Chebi-ID	metabolite	utilization activity	kind of utilization tested
22930	15963	ribitol	-	growth
22930	27613	amygdalin	+	growth
22930	62318	D-lyxose	-	growth
22930	32528	turanose	-	growth
22930	17266	L-sorbose	-	growth
22930	6731	melezitose	+	growth
22930	33942	ribose	-	growth
22930	30911	sorbitol	-	growth
22930	17992	sucrose	-	growth
68371		Potassium 5-ketogluconate	-	builds acid from
68371		Potassium 2-ketogluconate	-	builds acid from
68371	18403	L-arabitol	-	builds acid from
68371	18333	D-arabitol	-	builds acid from
68371	18287	L-fucose	-	builds acid from
68371	28847	D-fucose	-	builds acid from
68371	62318	D-lyxose	-	builds acid from
68371	32528	turanose	-	builds acid from
68371	17151	xylitol	-	builds acid from
68371	28087	glycogen	-	builds acid from
68371	28017	starch	-	builds acid from
68371	16634	raffinose	-	builds acid from
68371	6731	melezitose	+	builds acid from
68371	15443	inulin	-	builds acid from
68371	27082	trehalose	+	builds acid from
68371	28053	melibiose	-	builds acid from
68371	17716	lactose	+	builds acid from
68371	17306	maltose	-	builds acid from
68371	17057	cellobiose	+	builds acid from
68371	17814	salicin	+	builds acid from
68371	4853	esculin	+	builds acid from
68371	18305	arbutin	+	builds acid from
68371	27613	amygdalin	+	builds acid from
68371	59640	N-acetylglucosamine	+	builds acid from
68371	320061	methyl alpha-D-glucopyranoside	-	builds acid from
68371	43943	methyl alpha-D-mannoside	-	builds acid from
68371	17924	D-sorbitol	-	builds acid from
68371	16899	D-mannitol	+	builds acid from
68371	17268	myo-inositol	-	builds acid from
68371	16813	galactitol	-	builds acid from
68371	62345	L-rhamnose	-	builds acid from
68371	17266	L-sorbose	-	builds acid from
68371	16024	D-mannose	+	builds acid from
68371	15824	D-fructose	+	builds acid from
68371	17634	D-glucose	+	builds acid from
68371	12936	D-galactose	+	builds acid from
68371	74863	methyl beta-D-xylopyranoside	-	builds acid from
68371	15963	ribitol	-	builds acid from
68371	65328	L-xylose	-	builds acid from
68371	65327	D-xylose	-	builds acid from
68371	16988	D-ribose	-	builds acid from
68371	30849	L-arabinose	-	builds acid from
68371	17108	D-arabinose	-	builds acid from
68371	17113	erythritol	-	builds acid from
68371	17754	glycerol	-	builds acid from
117199	17632	nitrate	-	reduction
117199	16301	nitrite	-	reduction
117199	17632	nitrate	+	respiration
68379	17632	nitrate	+	reduction
68379	4853	esculin	+	hydrolysis
68379	16199	urea	-	hydrolysis
68379	5291	gelatin	-	hydrolysis
68379	16988	D-ribose	-	fermentation
68379	65327	D-xylose	-	fermentation
68379	16899	D-mannitol	+	fermentation
68379	17306	maltose	+	fermentation
68379	17716	lactose	+	fermentation
68379	17992	sucrose	+	fermentation
68379	28087	glycogen	-	fermentation

metabolite tests

@ref: 117199
Chebi-ID: 15688
metabolite: acetoin
voges-proskauer-test: +

enzymes

@ref	value	activity	ec
68382	alpha-fucosidase	-	3.2.1.51
68382	alpha-mannosidase	-	3.2.1.24
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52
68382	beta-glucosidase	+	3.2.1.21
68382	alpha-glucosidase	-	3.2.1.20
68382	beta-glucuronidase	-	3.2.1.31
68382	beta-galactosidase	+	3.2.1.23
68382	alpha-galactosidase	-	3.2.1.22
68382	naphthol-AS-BI-phosphohydrolase	+
68382	acid phosphatase	+	3.1.3.2
68382	alpha-chymotrypsin	+	3.4.21.1
68382	trypsin	-	3.4.21.4
68382	cystine arylamidase	+	3.4.11.3
68382	valine arylamidase	+
68382	leucine arylamidase	+	3.4.11.1
68382	lipase (C 14)	+
68382	esterase lipase (C 8)	+
68382	esterase (C 4)	+
68382	alkaline phosphatase	+	3.1.3.1
68379	catalase	+	1.11.1.6
68379	gelatinase	-
68379	urease	-	3.5.1.5
68379	beta-glucosidase	+	3.2.1.21
68379	N-acetyl-beta-glucosaminidase	-	3.2.1.52
68379	alpha-glucosidase	-	3.2.1.20
68379	beta-galactosidase	+	3.2.1.23
68379	beta-glucuronidase	-	3.2.1.31
68379	alkaline phosphatase	+	3.1.3.1
68379	pyrrolidonyl arylamidase	+	3.4.19.3
68379	pyrazinamidase	-	3.5.1.B15
117199	oxidase	-
117199	alcohol dehydrogenase	-	1.1.1.1
117199	catalase	-	1.11.1.6
117199	lysine decarboxylase	-	4.1.1.18
117199	ornithine decarboxylase	-	4.1.1.17

API coryne

@ref	NIT	PYZ	PYRA	PAL	beta GUR	beta GAL	alpha GLU	beta NAG	ESC	URE	GEL	Control	RIB	XYL	MAN	MAL	LAC	SAC	GLYG	CAT
47412	+	-	+	+	-	+	-	-	+	-	-	-	-	-	+	+	+	+	-	+

API zym

@ref	Control	Alkaline phosphatase	Esterase	Esterase Lipase	Lipase	Leucine arylamidase	Valine arylamidase	Cystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
117199	-	+	+	+	+	+	+	+	-	+	+	+	-	+	-	-	+	-	-	-

API 50CHac

@ref	Q	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
8425	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	+	-	-	+	-	-	-	-	-	-	-
8425	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	+	-	-	+	-	-	-	-	-	-	-
8425	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-
8425	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-
8425	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	+	-	-	+	-	-	-	-	+	-	-
8425	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	+	-	-	+	-	-	-	-	+	-	-
8425	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	+/-	+	-	+	-	-	-	-	+	-	-	+	-	-	-	-	+	-	-
8425	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	+	-	-	-	-	-	-	-	+	-	-

Isolation, sampling and environmental information

isolation

@ref	sample type
8425	cheese
47412	Cheese
67770	Cheese
117199	Food, Cheese

isolation source categories

Cat1: #Engineered
Cat2: #Food production
Cat3: #Dairy product

taxonmaps

@ref: 69479
File name: preview.99_113.png
url: https://microbeatlas.org/index.html?action=taxon&taxon_id=90_45;96_88;97_93;98_102;99_113&stattab=map
Last taxonomy: Lactobacillaceae
16S sequence: LC064894
Sequence Identity:
Total samples: 44444
soil counts: 1801
aquatic counts: 2397
animal counts: 39363
plant counts: 883

Safety information

risk assessment

@ref	pathogenicity human	biosafety level	biosafety level comment
8425	yes, in single cases	1	Risk group (German classification)
117199		1	Risk group (French classification)

Sequence information

16S sequences

@ref	description	accession	length	database	NCBI tax ID
20218	Lactobacillus zeae gene for 16S rRNA, partial sequence, strain: YIT 0078 (= ATCC 393)	AB008212	1563	ena	57037
20218	Lactobacillus casei strain BL23 16S ribosomal RNA gene, partial sequence	AF385770	1518	ena	543734
20218	Lactobacillus zeae ATCC 393 16S ribosomal RNA gene, partial sequence	AF429500	507	ena	219334
20218	Lactobacillus zeae strain ATCC 393 16S ribosomal RNA gene, partial sequence; 16S-23S intergenic spacer, complete sequence; and 23S ribosomal RNA gene, partial sequence	AF429587	537	ena	219334
20218	Lactobacillus casei strain ATCC 393 16S ribosomal RNA gene, partial sequence	AF469172	1517	ena	219334
20218	Lactobacillus casei subsp. casei ATCC 393 16S ribosomal RNA gene, partial sequence	AY196978	518	ena	219334
20218	L.casei small subunit ribosomal RNA	M23928	1574	ena	1582
20218	L.casei rrn operon, 16S-23S rRNA spacer (long), tRNA-Ile and tRNA-Ala genes	Z75478	432	ena	219334
20218	L.casei rrn operon, 16S-23S rRNA spacer (short)	Z75479	218	ena	219334
20218	Lactobacillus casei strain BCRC10697 16S ribosomal RNA gene, complete sequence	AY773945	1528	ena	1582
20218	Lactobacillus casei strain CECT 5275 16S ribosomal RNA gene, partial sequence	AY196967	518	ena	1582
20218	Lactobacillus casei strain DSM 20011 16S ribosomal RNA gene, partial sequence	EF468100	619	ena	1582
20218	Lactobacillus casei genes for 16S rRNA, 16S-23S internal transcribed spacer, tRNA-Ile, tRNA-Ala, 23S rRNA, partial and complete sequence, strain:JCM 1134	AB237516	577	ena	219334
20218	Lactobacillus casei genes for 16S rRNA, 16S-23S internal transcribed spacer, 23S rRNA, partial sequence, strain:JCM 1134	AB237517	364	ena	219334
20218	Lactobacillus casei gene for 16S rRNA, partial sequence, strain: JCM 1134	AB289057	681	ena	219334
20218	Lactobacillus casei subsp. casei 16S ribosomal RNA, partial sequence; 16S/23S intergenic spacer region, complete sequence; and 23S ribosomal RNA partial sequence	AF182729	685	ena	219334
20218	Lactobacillus casei gene for 16S rRNA	D16551	1522	ena	219334
20218	Lactobacillus casei gene for 16S rRNA, partial sequence, strain: NBRC 15883	AB626050	1495	ena	1582
20218	L.casei 16S rRNA gene	X61135	1491	ena	219334
67770	Lactobacillus casei gene for 16S ribosomal RNA, partial sequence, strain: JCM 1134	LC064894	1468	ena	1423732

Genome sequences

@ref	description	accession	assembly level	database	NCBI tax ID
66792	Lacticaseibacillus casei DSM 20011 = JCM 1134 = ATCC 393	GCA_000829055	complete	ncbi	1423732
66792	Lacticaseibacillus casei DSM 20011 = JCM 1134 = ATCC 393	GCA_000615205	contig	ncbi	1423732
66792	Lactobacillus casei DSM 20011 = JCM 1134	1423732.4	wgs	patric	1423732
66792	Lactobacillus casei JCM 1134	1236939.3	wgs	patric	1423732
66792	Lactobacillus casei subsp. casei ATCC 393	219334.10	plasmid	patric	1423732
66792	Lactobacillus casei subsp. casei ATCC 393	219334.11	plasmid	patric	1423732
66792	Lactobacillus casei subsp. casei ATCC 393	219334.4	complete	patric	1423732
66792	Lactobacillus casei casei ATCC 393	2630968676	draft	img	219334
66792	Lacticaseibacillus casei JCM 1134	2585427874	draft	img	1423732
66792	Lacticaseibacillus casei DSM 20011	2700989128	draft	img	1423732
67770	Lacticaseibacillus casei DSM 20011 = JCM 1134 = ATCC 393	GCA_001433735	scaffold	ncbi	1423732

GC content

@ref	GC-content	method
8425	49.0
67770	46.5	genome sequence analysis
67770	49

Genome-based predictions

predictions

trait	prediction	confidence	training_data
spore-forming	no	100	no
motile	no	94.27	no
flagellated	no	98.222	no
gram-positive	yes	94.192	no
anaerobic	no	94.723	no
aerobic	no	94.8	no
halophile	yes	79.581	no
spore-forming	no	91.345	no
glucose-util	yes	91.572	no
thermophile	no	98.541	yes
glucose-ferment	yes	87.545	no

External links

@ref: 8425

culture collection no.: CCUG 21451, IAM 12473, LMG 6904, DSM 20011, ATCC 393, NCDO 161, WDCM 00100, JCM 1134, BCRC 10697, CECT 475, CIP 103137, IFO 15883, KCTC 3109, NBRC 15883, NCIMB 11970, NRRL B-1922, VTT E-85225, IID 892, CCM 7088, NCTC 13641

straininfo link

@ref: 76030
straininfo: 9751

literature

topic	Pubmed-ID	title	authors	journal	DOI	year	mesh	topic2
Enzymology	14601	Comparative studies of lactic acid dehydrogenases in lactic acid bacteria. I. Purification and kinetics of the allosteric L-lactic acid dehydrogenase from Lactobacillus casei ssp. casei and Lactobacillus curvatus.	Hensel R, Mayr U, Stetter KO, Kandler O	Arch Microbiol	10.1007/BF00446658	1977	Allosteric Regulation, Cations, Divalent, Chromatography, Affinity, Drug Stability, Enzyme Activation, Fructosephosphates, Hydrogen-Ion Concentration, Kinetics, L-Lactate Dehydrogenase/isolation & purification, Lactobacillus/enzymology, Lactobacillus casei/*enzymology, Manganese, NAD, Pyruvates/metabolism	Phylogeny
Enzymology	823016	Purification, properties and immunological relationship of L (+)-lactate dehydrogenase from Lactobacillus casei.	Gordon GL, Doelle HW	Eur J Biochem	10.1111/j.1432-1033.1976.tb10720.x	1976	Cations, Divalent, Immunodiffusion, Immunoelectrophoresis, Kinetics, L-Lactate Dehydrogenase/analysis/isolation & purification/metabolism, Lactobacillus casei/enzymology, Macromolecular Substances, Molecular Weight, Pyruvates/pharmacology, Species Specificity, Structure-Activity Relationship, Sulfhydryl Reagents/pharmacology	Phylogeny
Genetics	1387195	Structural and functional analysis of two cryptic plasmids from Lactobacillus pentosus MD353 and Lactobacillus plantarum ATCC 8014.	Leer RJ, van Luijk N, Posno M, Pouwels PH	Mol Gen Genet	10.1007/BF00283847	1992	Amino Acid Sequence, Bacteriophage lambda/genetics, Base Sequence, DNA Replication/genetics, DNA, Bacterial/genetics, DNA, Viral/genetics, Escherichia coli/genetics, Lactobacillus/genetics, Molecular Sequence Data, Nucleic Acid Conformation, Plasmids/genetics, Repetitive Sequences, Nucleic Acid/*genetics, Transformation, Bacterial/genetics
Enzymology	1768113	Cloning and nucleotide sequence of the Lactobacillus casei lactate dehydrogenase gene.	Kim SF, Baek SJ, Pack MY	Appl Environ Microbiol	10.1128/aem.57.8.2413-2417.1991	1991	Amino Acid Sequence, Base Sequence, Cloning, Molecular, DNA, Bacterial, L-Lactate Dehydrogenase/genetics, Lactobacillus casei/enzymology/genetics/growth & development, Molecular Sequence Data	Genetics
Enzymology	3112575	Proteolytic activity of crude cell-free extract of Lactobacillus casei and Lactobacillus plantarum.	Hegazi FZ, Abo-Elnaga IG	Nahrung	10.1002/food.19870310309	1987	Dithiothreitol/pharmacology, Electrophoresis, Polyacrylamide Gel, Lactobacillus/enzymology, Lactobacillus casei/enzymology, Peptide Hydrolases/*analysis, Protease Inhibitors/pharmacology
Cultivation	3149890	Microbial caries induction in the roots of human teeth in vitro.	Kaufman HW, Pollock JJ, Gwinnett AJ	Arch Oral Biol	10.1016/0003-9969(88)90031-3	1988	Actinomyces/physiology, Bicuspid, Culture Media, Dental Caries/microbiology, Humans, Hydrogen-Ion Concentration, Lactobacillus casei/physiology, Microradiography, Microscopy, Electron, Scanning, Streptococcus mutans/physiology, Tooth Root/diagnostic imaging/*microbiology/ultrastructure	Pathogenicity
Metabolism	4327613	Effects of citrate on the composition and metabolism of Lactobacillus casei.	Branen AL, Keenan TW	Appl Microbiol	10.1128/am.21.6.993-998.1971	1971	Acetates/metabolism, Acids/biosynthesis, Bacterial Proteins/analysis, Butanones/biosynthesis, Carbohydrates/analysis, Carbon Isotopes, Cell-Free System, Chromatography, Chromatography, Gel, Citrates/metabolism, Culture Media, Electrophoresis, Disc, Fatty Acids, Nonesterified/biosynthesis, Hydrogen-Ion Concentration, Lactobacillus/analysis/growth & development/metabolism, Lipids/analysis/biosynthesis, Microscopy, Phase-Contrast, Phospholipids/biosynthesis, RNA, Bacterial/analysis, Silicon Dioxide, Spectrophotometry	Cultivation
Enzymology	7765447	Expression of Lactobacillus casei ATCC 393 beta-galactosidase encoded by plasmid pLZ15 in Lactococcus lactis CNRZ 1123.	Hemme D, Gaier W, Winters DA, Foucaud C, Vogel RF	Lett Appl Microbiol	10.1111/j.1472-765x.1994.tb00471.x	1994	Gene Expression Regulation, Enzymologic, Genetic Vectors, Lactobacillus casei/enzymology/genetics, Lactococcus lactis/genetics, Transformation, Bacterial, beta-Galactosidase/biosynthesis/*genetics
Metabolism	8025679	Glucose transport by the phosphoenolpyruvate:mannose phosphotransferase system in Lactobacillus casei ATCC 393 and its role in carbon catabolite repression.	Veyrat A, Monedero V, Perez-Martinez G	Microbiology (Reading)	10.1099/13500872-140-5-1141	1994	Biological Transport/genetics, Cell Division, Deoxyglucose/pharmacology, Drug Resistance, Microbial, Enzyme Induction, Galactose/metabolism, Gene Expression Regulation, Bacterial, Glucose/metabolism, Lactobacillus casei/genetics/growth & development/metabolism, Lactose/metabolism, Mannose/metabolism, Mutation, Phosphoenolpyruvate Sugar Phosphotransferase System/genetics/*metabolism, Phosphorylation, Ribose/metabolism
Phylogeny	8573516	Reclassification of Lactobacillus casei subsp. casei ATCC 393 and Lactobacillus rhamnosus ATCC 15820 as Lactobacillus zeae nom. rev., designation of ATCC 334 as the neotype of L. casei subsp. casei, and rejection of the name Lactobacillus paracasei.	Dicks LM, Du Plessis EM, Dellaglio F, Lauer E	Int J Syst Bacteriol	10.1099/00207713-46-1-337	1996	Base Sequence, DNA Primers, DNA, Bacterial/genetics, Lactobacillus/classification/genetics, Lactobacillus casei/classification/genetics, Molecular Sequence Data, Phylogeny, Polymorphism, Genetic, Random Amplified Polymorphic DNA Technique	Genetics
Genetics	9066115	Establishing a model to study the regulation of the lactose operon in Lactobacillus casei.	Gosalbes MJ, Monedero V, Alpert CA, Perez-Martinez G	FEMS Microbiol Lett	10.1111/j.1574-6968.1997.tb10271.x	1997	Base Sequence, Cloning, Molecular, Gene Expression Regulation, Bacterial/physiology, Genes, Bacterial/physiology, Genes, Reporter, Lac Operon/physiology, Lactobacillus casei/chemistry/genetics/metabolism, Molecular Sequence Data, Mutation/physiology, Sequence Analysis, DNA, Transcription, Genetic/*genetics, beta-Galactosidase	Enzymology
Metabolism	9324275	Peptidoglycan structure of Lactobacillus casei, a species highly resistant to glycopeptide antibiotics.	Billot-Klein D, Legrand R, Schoot B, van Heijenoort J, Gutmann L	J Bacteriol	10.1128/jb.179.19.6208-6212.1997	1997	Acetylation, Anti-Bacterial Agents/pharmacology, Chromatography, High Pressure Liquid, Drug Resistance, Microbial, Lactobacillus casei/chemistry/drug effects/metabolism, Mass Spectrometry, Molecular Weight, Oligopeptides/chemistry/isolation & purification, Penicillin G/pharmacology, Peptidoglycan/*chemistry/metabolism	Pathogenicity
Enzymology	9352913	Catabolite repression in Lactobacillus casei ATCC 393 is mediated by CcpA.	Monedero V, Gosalbes MJ, Perez-Martinez G	J Bacteriol	10.1128/jb.179.21.6657-6664.1997	1997	Acetylglucosaminidase/biosynthesis, Amino Acid Sequence, Bacillus subtilis/genetics, Bacterial Proteins, Base Sequence, Cloning, Molecular, DNA-Binding Proteins/genetics, Enzyme Repression, Gene Expression Regulation, Bacterial, Gene Expression Regulation, Enzymologic, Genetic Complementation Test, Glycoside Hydrolases, Gram-Positive Bacteria/genetics, Lac Operon/genetics, Lactobacillus casei/genetics, Molecular Sequence Data, Mutagenesis, Repressor Proteins/*genetics, Sequence Analysis, DNA, Sequence Homology, Amino Acid, Transcription, Genetic, beta-Galactosidase/biosynthesis	Genetics
Biotechnology	10347876	Stable expression of the Lactobacillus casei bacteriophage A2 repressor blocks phage propagation during milk fermentation.	Alvarez MA, Rodriguez A, Suarez JE	J Appl Microbiol	10.1046/j.1365-2672.1999.00728.x	1999	Animals, Bacteriophages/growth & development, Fermentation, Food Microbiology, Gene Expression, Lactobacillus casei/genetics/virology, Milk/microbiology, Phenotype, Repressor Proteins/*genetics	Phenotype
Metabolism	10383959	Elements involved in catabolite repression and substrate induction of the lactose operon in Lactobacillus casei.	Gosalbes MJ, Monedero V, Perez-Martinez G	J Bacteriol	10.1128/JB.181.13.3928-3934.1999	1999	Bacterial Proteins/genetics/metabolism, DNA-Binding Proteins/genetics, Enzyme Induction, Enzyme Repression, Gene Expression Regulation, Bacterial, Genes, Reporter, Glucose/pharmacology, Glucuronidase/biosynthesis/genetics, Glycoside Hydrolases, Lac Operon, Lactobacillus casei/drug effects/enzymology/genetics, Lactose/pharmacology, Mutagenesis, Phosphoenolpyruvate Sugar Phosphotransferase System/genetics, RNA-Binding Proteins/genetics/metabolism, Repressor Proteins/genetics, Transcription, Genetic, beta-Galactosidase/genetics	Enzymology
Enzymology	10438743	Transport of D-xylose in Lactobacillus pentosus, Lactobacillus casei, and Lactobacillus plantarum: evidence for a mechanism of facilitated diffusion via the phosphoenolpyruvate:mannose phosphotransferase system.	Chaillou S, Pouwels PH, Postma PW	J Bacteriol	10.1128/JB.181.16.4768-4773.1999	1999	Adenosine Triphosphate/metabolism, Biological Transport, Active/physiology, Carbon Radioisotopes/pharmacokinetics, Diffusion, Genetic Complementation Test, Kinetics, Lactobacillus casei/enzymology/genetics/growth & development, Mannose/metabolism, Mutation, Phosphoenolpyruvate/metabolism, Phosphoenolpyruvate Sugar Phosphotransferase System/metabolism/physiology, Plasmids, Species Specificity, Transformation, Genetic, Xylose/*pharmacokinetics	Metabolism
Phylogeny	10473394	Comparison of ribotyping, randomly amplified polymorphic DNA analysis, and pulsed-field gel electrophoresis in typing of Lactobacillus rhamnosus and L. casei strains.	Tynkkynen S, Satokari R, Saarela M, Mattila-Sandholm T, Saxelin M	Appl Environ Microbiol	10.1128/AEM.65.9.3908-3914.1999	1999	Bacterial Typing Techniques, DNA Primers, Deoxyribonuclease EcoRI/metabolism, Electrophoresis, Gel, Pulsed-Field, Genes, rRNA, Genotype, Lactobacillus/classification/*genetics, Lactobacillus casei/classification/genetics, Polymerase Chain Reaction/methods, Random Amplified Polymorphic DNA Technique, Species Specificity	Enzymology
Metabolism	10592512	Enhanced production of L-(+)-lactic acid in chemostat by Lactobacillus casei DSM 20011 using ion-exchange resins and cross-flow filtration in a fully automated pilot plant controlled via NIR.	Gonzalez-Vara Y R A, Vaccari G, Dosi E, Trilli A, Rossi M, Matteuzzi D	Biotechnol Bioeng	10.1002/(SICI)1097-0290(20000120)67:2<147::AID-BIT4>3.0.CO;2-F	2000	Automation, Fermentation, Filtration/methods, Glucose/metabolism, Lactic Acid/biosynthesis, Lactobacillus casei/metabolism, Resins, Plant, Spectroscopy, Near-Infrared/instrumentation/methods	Biotechnology
Metabolism	10613875	Genetics of L-sorbose transport and metabolism in Lactobacillus casei.	Yebra MJ, Veyrat A, Santos MA, Perez-Martinez G	J Bacteriol	10.1128/JB.182.1.155-163.2000	2000	Amino Acid Sequence, Bacterial Proteins/genetics/metabolism, Base Sequence, Biological Transport/genetics, Cell Division/genetics, Cloning, Molecular, Fructose-Bisphosphate Aldolase/genetics/metabolism, Gene Expression Regulation, Bacterial, Gene Silencing, Genes, Bacterial, Glucose/metabolism, Lactobacillus casei/genetics/growth & development/metabolism, Molecular Sequence Data, Multigene Family, Mutation, Open Reading Frames, Phosphoenolpyruvate Sugar Phosphotransferase System/genetics/metabolism, Sequence Analysis, Sequence Homology, Amino Acid, Sorbose/genetics/*metabolism, Suppression, Genetic, Transcription, Genetic	Genetics
Phylogeny	10758849	Comparative analysis of the genes encoding 23S-5S rRNA intergenic spacer regions of Lactobacillus casei-related strains.	Chen H, Lim CK, Lee YK, Chan YN	Int J Syst Evol Microbiol	10.1099/00207713-50-2-471	2000	Base Sequence, Cloning, Molecular, Genes, rRNA, Genetic Variation, Lactobacillus/classification/genetics, Lactobacillus casei/classification/genetics, Molecular Sequence Data, Nucleic Acid Hybridization, Polymerase Chain Reaction, Polymorphism, Restriction Fragment Length, RNA, Ribosomal, 23S/genetics, RNA, Ribosomal, 5S/genetics, Sequence Analysis, DNA	Enzymology
Biotechnology	10831443	Generation of food-grade recombinant lactic acid bacterium strains by site-specific recombination.	Martin MC, Alonso JC, Suarez JE, Alvarez MA	Appl Environ Microbiol	10.1128/AEM.66.6.2599-2604.2000	2000	Animals, Attachment Sites, Microbiological, Bacteriophages/genetics, DNA Nucleotidyltransferases/genetics, DNA-Binding Proteins, Fermentation, Food Microbiology, Genetic Vectors, Integrases/genetics, Lactobacillus casei/genetics/virology, Milk/metabolism, Plasmids/genetics, Recombinases, *Recombination, Genetic, Repressor Proteins/genetics/metabolism, Viral Proteins, Viral Regulatory and Accessory Proteins	Metabolism
Metabolism	11073938	Expression of cbsA encoding the collagen-binding S-protein of Lactobacillus crispatus JCM5810 in Lactobacillus casei ATCC 393(T).	Martinez B, Sillanpaa J, Smit E, Korhonen TK, Pouwels PH	J Bacteriol	10.1128/JB.182.23.6857-6861.2000	2000	Bacterial Proteins/biosynthesis/genetics, Cell Membrane/metabolism, Integrins/biosynthesis/genetics, Lactobacillus/genetics, Lactobacillus casei/genetics/metabolism, Membrane Glycoproteins, Membrane Proteins/biosynthesis/genetics, Receptors, Collagen
Phylogeny	11386416	Characterization of the Lactobacillus casei group and the Lactobacillus acidophilus group by automated ribotyping.	Ryu CS, Czajka JW, Sakamoto M, Benno Y	Microbiol Immunol	10.1111/j.1348-0421.2001.tb02618.x	2001	Humans, Lactobacillus acidophilus/classification/genetics, Lactobacillus casei/classification/genetics, Ribotyping/*methods, Species Specificity	Pathogenicity
Phylogeny	11760954	Comparative sequence analysis of a recA gene fragment brings new evidence for a change in the taxonomy of the Lactobacillus casei group.	Felis GE, Dellaglio F, Mizzi L, Torriani S	Int J Syst Evol Microbiol	10.1099/00207713-51-6-2113	2001	DNA, Bacterial/genetics, Lactobacillus casei/classification/genetics, Molecular Sequence Data, Phylogeny, Rec A Recombinases/genetics, *Sequence Analysis, DNA, Species Specificity	Transcriptome
Phylogeny	11837314	The status of the species Lactobacillus casei (Orla-Jensen 1916) Hansen and Lessel 1971 and Lactobacillus paracasei Collins et al. 1989. Request for an opinion.	Dellaglio F, Felis GE, Torriani S	Int J Syst Evol Microbiol	10.1099/00207713-52-1-285	2002	Lactobacillus/classification, Lactobacillus casei/classification, *Terminology as Topic
Phylogeny	12656154	Significant differences between Lactobacillus casei subsp. casei ATCC 393T and a commonly used plasmid-cured derivative revealed by a polyphasic study.	Acedo-Felix E, Perez-Martinez G	Int J Syst Evol Microbiol	10.1099/ijs.0.02325-0	2003	Base Sequence, DNA, Bacterial/genetics, DNA, Ribosomal/genetics, Lactobacillus casei/classification/genetics, Molecular Sequence Data, Phenotype, Plasmids/genetics, RNA, Bacterial/genetics, RNA, Ribosomal, 16S/genetics, Random Amplified Polymorphic DNA Technique, Ribotyping, Species Specificity	Genetics
Genetics	14631071	Homology modeling of the central catalytic domain of insertion sequence ISLC3 isolated from Lactobacillus casei ATCC 393.	Lin TH, Tsai KC, Lo TC	Protein Eng	10.1093/protein/gzg107	2003	Amino Acid Sequence, Bacterial Proteins/chemistry/genetics, Base Sequence, Catalytic Domain, DNA Transposable Elements/genetics, Hydrogen Bonding, Lactobacillus casei/chemistry/genetics, Models, Molecular, Molecular Sequence Data, Molecular Structure, Protein Conformation, Sequence Alignment
Cultivation	14725858	Osmotic response in Lactobacillus casei ATCC 393: biochemical and biophysical characteristics of membrane.	Machado MC, Lopez CS, Heras H, Rivas EA	Arch Biochem Biophys	10.1016/j.abb.2003.11.001	2004	Bile Acids and Salts/pharmacology, Cell Membrane/chemistry/physiology, Cell Membrane Permeability, Culture Media, Diphenylhexatriene/chemistry, Fatty Acids/analysis/chemistry, Fluorescence Polarization, Glycolipids/analysis, Hydrophobic and Hydrophilic Interactions, Lactobacillus casei/chemistry/genetics/physiology, Liposomes/chemistry, Membrane Fluidity, Membrane Lipids/analysis, Osmotic Pressure, Phospholipids/analysis, Protons, Saline Solution, Hypertonic/pharmacology	Lipids
Biotechnology	15321687	Nisin-controlled expression of Norwalk virus VP60 protein in Lactobacillus casei.	Martin MC, Fernandez M, Martin-Alonso JM, Parra F, Boga JA, Alvarez MA	FEMS Microbiol Lett	10.1016/j.femsle.2004.07.002	2004	Anti-Bacterial Agents/pharmacology, Antigens, Viral/biosynthesis/genetics, Bacterial Proteins/genetics, Capsid Proteins/biosynthesis/genetics, Food Microbiology, Gene Expression Regulation, Histidine Kinase, Lactobacillus casei/genetics, Nisin/pharmacology, Norwalk virus/*immunology, Protein Kinases/genetics, Transcription Factors/genetics
Phylogeny	15381972	Lactobacillus casei, Lactobacillus rhamnosus, and Lactobacillus zeae isolates identified by sequence signature and immunoblot phenotype.	Dobson CM, Chaban B, Deneer H, Ziola B	Can J Microbiol	10.1139/w04-044	2004	Bacterial Proteins/analysis/immunology/isolation & purification, Chaperonin 60/genetics, DNA, Bacterial/chemistry/isolation & purification, DNA, Ribosomal/chemistry/isolation & purification, DNA, Ribosomal Spacer/chemistry/isolation & purification, Genes, rRNA, Immunoblotting, Lactobacillus/*classification/genetics, Lactobacillus casei/classification/genetics, Molecular Sequence Data, Phylogeny, Proteome/analysis/immunology/isolation & purification, RNA, Ribosomal, 16S/genetics, Sequence Analysis, DNA, Sequence Homology	Enzymology
Enzymology	15610420	Cell wall modifications during osmotic stress in Lactobacillus casei.	Piuri M, Sanchez-Rivas C, Ruzal SM	J Appl Microbiol	10.1111/j.1365-2672.2004.02428.x	2005	Bacteriological Techniques, Cell Wall/chemistry/ultrastructure, Drug Resistance, Electrophoresis, Polyacrylamide Gel, Hydrolysis, Lactobacillus casei/chemistry/physiology/ultrastructure, Microscopy, Electron, Osmosis, Penicillin-Binding Proteins/analysis, Peptidoglycan/analysis	Stress
Metabolism	15796593	Malolactic fermentation in wine with Lactobacillus casei cells immobilized on Delignified cellulosic material.	Agouridis N, Bekatorou A, Nigam P, Kanellaki M	J Agric Food Chem	10.1021/jf048736t	2005	Carboxylic Acids/analysis, Cells, Immobilized, Cellulose, Fermentation, Food Handling/methods, Lactobacillus casei/metabolism, Malates/metabolism, Microscopy, Electron, Volatilization, *Wine/analysis
Genetics	15975621	Complete genomic sequence of the temperate bacteriophage PhiAT3 isolated from Lactobacillus casei ATCC 393.	Lo TC, Shih TC, Lin CF, Chen HW, Lin TH	Virology	10.1016/j.virol.2005.05.022	2005	Bacteriophages/chemistry/genetics/ultrastructure, Chromosomes, Bacterial/genetics/metabolism, DNA, Viral/biosynthesis, Genome, Viral, Integrases/genetics, Lactobacillus casei/virology, Molecular Sequence Data, Multigene Family, Open Reading Frames, RNA, Transfer/genetics/metabolism, Viral Proteins/genetics/metabolism, Virus Integration	Metabolism
Phylogeny	16094870	DNA-based classification and sequence heterogeneities in the 16S rRNA genes of Lactobacillus casei/paracasei and related species.	Vasquez A, Molin G, Pettersson B, Antonsson M, Ahrne S	Syst Appl Microbiol	10.1016/j.syapm.2005.02.011	2005	Base Sequence, DNA, Bacterial/analysis/genetics, DNA, Ribosomal/analysis, Electrophoresis, Agar Gel/methods, Genes, rRNA, Genetic Variation, Humans, Lactobacillus/classification/genetics, Lactobacillus casei/classification/genetics, Molecular Sequence Data, Phylogeny, Polymerase Chain Reaction, Polymorphism, Genetic, Polymorphism, Restriction Fragment Length, Prohibitins, RNA, Ribosomal, 16S/genetics, Restriction Mapping, *Ribotyping, Sequence Analysis, DNA	Enzymology
Phylogeny	16295661	Ribotyping of Lactobacillus casei group strains isolated from dairy products.	Svec P, Drab V, Sedlacek I	Folia Microbiol (Praha)	10.1007/BF02931570	2005	Dairy Products/microbiology, Lactobacillus casei/classification/*isolation & purification, Lactobacillus rhamnosus/classification/isolation & purification, Phenotype, Ribotyping, Species Specificity	Enzymology
Pathogenicity	16620202	Effects of Lactobacillus strains on cancer cell proliferation and oxidative stress in vitro.	Choi SS, Kim Y, Han KS, You S, Oh S, Kim SH	Lett Appl Microbiol	10.1111/j.1472-765X.2006.01913.x	2006	Antineoplastic Agents/pharmacology, Antioxidants/pharmacology, Apoptosis, Cell Line, Tumor, Cell Proliferation/drug effects, Cell Survival/drug effects, DNA Fragmentation, Humans, Lactobacillus/chemistry, Lactobacillus acidophilus/chemistry, Lactobacillus casei/chemistry, Microscopy, Fluorescence, Oxidative Stress/drug effects, Polysaccharides, Bacterial/pharmacology, Propidium/metabolism, Staining and Labeling	Stress
Pathogenicity	16713190	Antibacterial activities of inorganic agents on six bacteria associated with oral infections by two susceptibility tests.	Fang M, Chen JH, Xu XL, Yang PH, Hildebrand HF	Int J Antimicrob Agents	10.1016/j.ijantimicag.2006.01.008	2006	Anti-Bacterial Agents/pharmacology, Bacteria/drug effects, Microbial Sensitivity Tests/methods, Mouth Diseases/microbiology, Silver/pharmacology, Zinc/pharmacology
	17497025	Impact of lactic Acid bacteria on dendritic cells from allergic patients in an experimental model of intestinal epithelium.	Ratajczak C, Duez C, Grangette C, Pochard P, Tonnel AB, Pestel J	J Biomed Biotechnol	10.1155/2007/71921	2007
Metabolism	17614152	Arsenic removal by native and chemically modified lactic acid bacteria.	Halttunen T, Finell M, Salminen S	Int J Food Microbiol	10.1016/j.ijfoodmicro.2007.06.002	2007	Arsenic/metabolism, Arsenicals/metabolism, Biodegradation, Environmental, Consumer Product Safety, Dose-Response Relationship, Drug, Humans, Hydrogen-Ion Concentration, Lactobacillus/metabolism, Water Microbiology, Water Pollutants, Chemical/metabolism, Water Purification/*methods	Pathogenicity
Phylogeny	17704267	Multilocus sequence typing of Lactobacillus casei reveals a clonal population structure with low levels of homologous recombination.	Diancourt L, Passet V, Chervaux C, Garault P, Smokvina T, Brisse S	Appl Environ Microbiol	10.1128/AEM.01095-07	2007	Bacterial Proteins/genetics/metabolism, Bacterial Typing Techniques, Base Sequence, DNA, Bacterial/analysis, Lactobacillus casei/classification/genetics, Molecular Sequence Data, Phylogeny, Recombination, Genetic, Ribosomal Proteins/genetics/metabolism, Sequence Analysis, DNA	Metabolism
Metabolism	17827311	Induction of immune responses in mice after intragastric administration of Lactobacillus casei producing porcine parvovirus VP2 protein.	Xu Y, Li Y	Appl Environ Microbiol	10.1128/AEM.00436-07	2007	Animals, Capsid Proteins/administration & dosage/genetics/immunology/metabolism, Drug Administration Routes, Drug Delivery Systems, Immunity, Mucosal/drug effects/immunology, Lactobacillus casei/genetics/immunology/metabolism, Mice, Mice, Inbred BALB C, Recombinant Proteins/administration & dosage/metabolism	Pathogenicity
Pathogenicity	17993372	Incorporation of citrus fibers in fermented milk containing probiotic bacteria.	Sendra E, Fayos P, Lario Y, Fernandez-Lopez J, Sayas-Barbera E, Perez-Alvarez JA	Food Microbiol	10.1016/j.fm.2007.09.003	2007	Animals, Bifidobacterium/growth & development, Citrus/chemistry, Colony Count, Microbial, Fermentation, Food Handling/methods, Food Preservation/methods, Humans, Lactobacillus acidophilus/growth & development, Lactobacillus casei/growth & development, Milk/microbiology, Models, Biological, Probiotics, Time Factors
	18034821	Construction of recombinant Lactobacillus casei efficiently surface displayed and secreted porcine parvovirus VP2 protein and comparison of the immune responses induced by oral immunization.	Yigang XU, Yijing LI	Immunology	10.1111/j.1365-2567.2007.02738.x	2007	Administration, Oral, Animals, Antibodies, Viral/biosynthesis, Antigens, Viral/immunology, Capsid Proteins/immunology, Genetic Vectors, Immunity, Mucosal, Immunization/methods, Immunoglobulin A/biosynthesis, Immunoglobulin G/biosynthesis, Lactobacillus casei/genetics/immunology, Mice, Mice, Inbred BALB C, Parvoviridae Infections/immunology, Parvovirus/immunology, Recombinant Proteins/immunology, Vaccines, Synthetic/immunology, Viral Vaccines/immunology
Phylogeny	18326671	Taxonomic and strain-specific identification of the probiotic strain Lactobacillus rhamnosus 35 within the Lactobacillus casei group.	Coudeyras S, Marchandin H, Fajon C, Forestier C	Appl Environ Microbiol	10.1128/AEM.02286-07	2008	Base Sequence, DNA Fingerprinting, DNA Primers/genetics, DNA, Bacterial/chemistry/genetics, Electrophoresis, Gel, Pulsed-Field, Electrophoresis, Polyacrylamide Gel, Genes, rRNA, Hot Temperature, Lactobacillus rhamnosus/classification/genetics, Molecular Sequence Data, Nucleic Acid Denaturation, Nucleic Acid Hybridization, Phylogeny, Polymerase Chain Reaction/methods, Probiotics, Ribotyping, Sensitivity and Specificity, Sequence Alignment, Sequence Analysis, DNA, Sequence Homology, Nucleic Acid	Enzymology
Pathogenicity	18493226	Fluoride release and antibacterial activity of selected dental materials.	Marczuk-Kolada G, Jakoniuk P, Mystkowska J, Luczaj-Cepowicz E, Waszkiel D, Dabrowski JR, Leszczynska K	Postepy Hig Med Dosw (Online)	453293	2006	Anti-Bacterial Agents/chemistry, Cariostatic Agents/chemistry, Compomers/chemistry, Composite Resins/chemistry, Diffusion, Fluorides/chemistry, Glass Ionomer Cements/chemistry, Humans, Resin Cements/chemistry, Resins, Synthetic/chemistry, Streptococcus mutans/drug effects
Phylogeny	18599731	The type strain of Lactobacillus casei is ATCC 393, ATCC 334 cannot serve as the type because it represents a different taxon, the name Lactobacillus paracasei and its subspecies names are not rejected and the revival of the name 'Lactobacillus zeae' contravenes Rules 51b (1) and (2) of the International Code of Nomenclature of Bacteria. Opinion 82.		Int J Syst Evol Microbiol	10.1099/ijs.0.2008/005330-0	2008	Bacteriology/standards, Lactobacillus/classification, Lactobacillus casei/classification, *Terminology as Topic
	18668418	Microencapsulation of a probiotic bacteria with alginate-gelatin and its properties.	Li XY, Chen XG, Cha DS, Park HJ, Liu CS	J Microencapsul	10.1080/02652040802328685	2008	Alginates/chemistry, Capsules, Drug Compounding/methods, Gastrointestinal Contents/chemistry, Gelatin/chemistry, Glucuronic Acid/chemistry, Hexuronic Acids/chemistry, Lactobacillus casei/cytology, Particle Size, Probiotics/*administration & dosage
Pathogenicity	18818469	Antibacterial effects of three experimental quaternary ammonium salt (QAS) monomers on bacteria associated with oral infections.	Xiao YH, Chen JH, Fang M, Xing XD, Wang H, Wang YJ, Li F	J Oral Sci	10.2334/josnusd.50.323	2008	Anti-Bacterial Agents/chemistry/pharmacology, Bacteria, Anaerobic/drug effects, Colony Count, Microbial, Microbial Sensitivity Tests, Molecular Structure, Mouth Diseases/microbiology, Quaternary Ammonium Compounds/chemistry/*pharmacology, Staphylococcus aureus/drug effects
Enzymology	19131699	Construction of recombinant Lactobacillus casei strains using splicing by overlap extension.	Jeong DW, Lee JH, Lee HJ	J Microbiol Biotechnol	8152	2008	Cloning, Molecular/methods, DNA Primers, DNA, Bacterial/genetics, DNA, Recombinant, Green Fluorescent Proteins/genetics/metabolism, Lactobacillus casei/genetics/metabolism, Polymerase Chain Reaction/methods	Metabolism
Metabolism	20355041	Effect of prebiotics on viability and growth characteristics of probiotics in soymilk.	Yeo SK, Liong MT	J Sci Food Agric	10.1002/jsfa.3808	2010	Bifidobacterium/growth & development/metabolism, Carbohydrates, Dietary Supplements, Food Microbiology, Hydrolysis, Lactic Acid/metabolism, Lactobacillus/growth & development/metabolism, Mannitol, Microbial Viability, Polysaccharides/metabolism, Prebiotics, Probiotics, *Soy Milk, Stem Cells, alpha-Galactosidase/metabolism	Biotechnology
Pathogenicity	20389120	Rapid detection and identification of probiotic Lactobacillus casei ATCC 393 by multiplex PCR.	Karapetsas A, Vavoulidis E, Galanis A, Sandaltzopoulos R, Kourkoutas Y	J Mol Microbiol Biotechnol	10.1159/000308518	2010	Bacterial Proteins/genetics, Bacteriological Techniques/methods, Chaperonin 60/genetics, Cheese/microbiology, DNA Primers/genetics, DNA, Bacterial/genetics, Humans, Lactobacillus casei/genetics/isolation & purification, Polymerase Chain Reaction/methods, Probiotics, Sensitivity and Specificity	Enzymology
Pathogenicity	20560350	[Influence of cross-protection on the survival of Lactobacillus casei ATCC 393].	Xue F, Zhang J, Du G, Chen J	Wei Sheng Wu Xue Bao		2010	Bile Acids and Salts/pharmacology, Cross Protection/drug effects/physiology, Hydrogen Peroxide/pharmacology, Lactobacillus casei/genetics/physiology, Stress, Physiological/*physiology, Temperature
Pathogenicity	20583474	The influence of some probiotic supernatants on the growth and virulence features expression of several selected enteroaggregative E. coli clinical strains.	Lazar V, Miyazaki Y, Hanawa T, Chifiriuc MC, Ditu LM, Marutescu L, Bleotu C, Kamiya S	Roum Arch Microbiol Immunol		2009	Bacterial Adhesion, Bifidobacterium/growth & development, Cell Line, Colony Count, Microbial, Culture Media, Conditioned/chemistry/pharmacology, Diarrhea/microbiology, Enterococcus faecium/growth & development, Epithelial Cells/microbiology, Escherichia coli/drug effects/growth & development/pathogenicity, Escherichia coli Infections/microbiology, Humans, Lactobacillus casei/growth & development, Probiotics, Virulence	Cultivation
Metabolism	21070005	Expression of Lactobacillus reuteri Pg4 collagen-binding protein gene in Lactobacillus casei ATCC 393 increases its adhesion ability to Caco-2 cells.	Hsueh HY, Yueh PY, Yu B, Zhao X, Liu JR	J Agric Food Chem	10.1021/jf1035756	2010	Bacterial Adhesion, Bacterial Proteins/genetics/metabolism, Caco-2 Cells, Epithelial Cells/microbiology, Gene Expression, Humans, Intestines/microbiology, Lactobacillus/genetics/metabolism, Lactobacillus casei/genetics/*physiology, Open Reading Frames, Up-Regulation	Pathogenicity
Metabolism	21160205	Effect of probiotic-fermented milk administration on gastrointestinal survival of Lactobacillus casei ATCC 393 and modulation of intestinal microbial flora.	Sidira M, Galanis A, Ypsilantis P, Karapetsas A, Progaki Z, Simopoulos C, Kourkoutas Y	J Mol Microbiol Biotechnol	10.1159/000321115	2010	Animals, Bile Acids and Salts/pharmacology, Cultured Milk Products/microbiology, Gastric Juice/microbiology, Gastrointestinal Tract/microbiology, Lactobacillus casei/growth & development/metabolism/physiology, Malus/microbiology, Metagenome/physiology, Microbial Viability/drug effects, Probiotics, Rats	Genetics
Metabolism	21794012	Effect of cellooligosaccharide or synbiotic feeding on growth performance, fecal condition and hormone concentrations in Holstein calves.	Hasunuma T, Kawashima K, Nakayama H, Murakami T, Kanagawa H, Ishii T, Akiyama K, Yasuda K, Terada F, Kushibiki S	Anim Sci J	10.1111/j.1740-0929.2010.00861.x	2011	Animal Feed, Animals, Cattle/growth & development/metabolism/physiology, Feces/microbiology, Female, Growth Hormone/blood, Hormones/*blood, Insulin/blood
Phylogeny	22021580	Lactobacillus brantae sp. nov., isolated from faeces of Canada geese (Branta canadensis).	Volokhov DV, Amselle M, Beck BJ, Popham DL, Whittaker P, Wang H, Kerrigan E, Chizhikov VE	Int J Syst Evol Microbiol	10.1099/ijs.0.033852-0	2011	Animals, Bacterial Typing Techniques, Base Composition, Carbohydrates/analysis, DNA, Bacterial/genetics, DNA, Ribosomal Spacer/genetics, Fatty Acids/analysis, Feces/microbiology, Geese/microbiology, Genes, Bacterial, Genotype, Lactobacillus/classification/genetics/isolation & purification, Molecular Sequence Data, Phenotype, *Phylogeny, RNA, Ribosomal, 16S/genetics, Sequence Analysis, DNA, Species Specificity	Genetics
	22554894	Distinct adhesion of probiotic strain Lactobacillus casei ATCC 393 to rat intestinal mucosa.	Saxami G, Ypsilantis P, Sidira M, Simopoulos C, Kourkoutas Y, Galanis A	Anaerobe	10.1016/j.anaerobe.2012.04.002	2012	Animals, Bacterial Adhesion, Bacterial Load, Cultured Milk Products/microbiology, DNA, Bacterial/genetics, Intestinal Mucosa/microbiology, Intestine, Large/microbiology, Intestine, Small/microbiology, Lactobacillus casei/genetics/growth & development/physiology, Malus, Microbial Sensitivity Tests, Polymerase Chain Reaction, Probiotics/administration & dosage, Rats, Rats, Wistar
Pathogenicity	22805939	Growth-inhibiting effects of Paeonia lactiflora root steam distillate constituents and structurally related compounds on human intestinal bacteria.	Ngan LT, Moon JK, Kim JH, Shibamoto T, Ahn YJ	World J Microbiol Biotechnol	10.1007/s11274-011-0961-6	2011	Amoxicillin/pharmacology, Anti-Bacterial Agents/chemistry/isolation & purification/pharmacology, Enterobacteriaceae/drug effects, Humans, Lactobacillales/drug effects, Microbial Sensitivity Tests, Paeonia/chemistry, Plant Extracts/chemistry/isolation & purification/pharmacology, Plant Roots/*chemistry, Steam, Structure-Activity Relationship, Tetracycline/pharmacology	Enzymology
Enzymology	23064454	Stable integration and expression of heterologous genes in several lactobacilli using an integration vector constructed from the integrase and attP sequences of phage PhiAT3 isolated from Lactobacillus casei ATCC 393.	Lin CF, Lo TC, Kuo YC, Lin TH	Appl Microbiol Biotechnol	10.1007/s00253-012-4393-5	2012	Attachment Sites, Microbiological, Bacteriophages/enzymology/genetics, Genetic Vectors, Genetics, Microbial/methods, Genomic Instability, Integrases/genetics, Lactobacillus/genetics/virology, Lactobacillus fermentum, Lactobacillus rhamnosus, Lactococcus lactis, Molecular Biology/methods, Promoter Regions, Genetic
	23072864	The effects of microencapsulated Lactobacillus casei on tumour cell growth: In vitro and in vivo studies.	Dwivedi A, Nomikou N, Nigam PS, McHale AP	Int J Med Microbiol	10.1016/j.ijmm.2012.09.002	2012	Animals, Biological Therapy/methods, Capsules/administration & dosage, Cell Line, Cell Survival, Disease Models, Animal, Drug Carriers/administration & dosage, Histocytochemistry, Lactobacillus casei/physiology, Mice, Mice, Inbred C3H, Neoplasms/pathology/*therapy, Treatment Outcome
Phylogeny	23099260	Characterization of the Lactobacillus casei group based on the profiling of ribosomal proteins coded in S10-spc-alpha operons as observed by MALDI-TOF MS.	Sato H, Torimura M, Kitahara M, Ohkuma M, Hotta Y, Tamura H	Syst Appl Microbiol	10.1016/j.syapm.2012.08.008	2012	Cluster Analysis, DNA, Bacterial/chemistry/genetics, Lactobacillus casei/chemistry/classification/genetics, Molecular Sequence Data, Molecular Weight, Operon, Phylogeny, Ribosomal Proteins/chemistry/genetics, Sequence Analysis, DNA, *Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	Genetics
Metabolism	23433374	Use of Lactobacillus acidophilus and Lactobacillus casei for a potential probiotic legume-based fermented product using pigeon pea (Cajanus cajan).	Parra K, Ferrer M, Pinero M, Barboza Y, Medina LM	J Food Prot	10.4315/0362-028X.JFP-12-138	2013	Animals, Cajanus/metabolism/microbiology, Colony Count, Microbial, Fermentation, Food Handling/methods, Humans, Hydrogen-Ion Concentration, Lactobacillus acidophilus/growth & development/metabolism, Lactobacillus casei/growth & development/*metabolism, Microbial Viability, Milk, Probiotics	Pathogenicity
	23498002	Monitoring survival of Lactobacillus casei ATCC 393 in probiotic yogurts using an efficient molecular tool.	Sidira M, Saxami G, Dimitrellou D, Santarmaki V, Galanis A, Kourkoutas Y	J Dairy Sci	10.3168/jds.2012-6343	2013	Food Storage, Hydrogen-Ion Concentration, Lactobacillus casei/physiology, Lactobacillus delbrueckii/physiology, Multiplex Polymerase Chain Reaction/methods, Probiotics/standards, Time Factors, Yogurt/*microbiology/standards
Metabolism	23824609	Increase of the adhesion ability and display of a rumen fungal xylanase on the cell surface of Lactobacillus casei by using a listerial cell-wall-anchoring protein.	Hsueh HY, Yu B, Liu CT, Liu JR	J Sci Food Agric	10.1002/jsfa.6298	2013	Animals, Avena/metabolism, Bacterial Adhesion, Bacterial Proteins/genetics/metabolism, Caco-2 Cells, Cell Wall/metabolism, Food Additives, Fungal Proteins/metabolism, Genes, Bacterial, Humans, Intestinal Mucosa/metabolism, Lactobacillus casei/enzymology/genetics, Listeria monocytogenes/enzymology/genetics, Probiotics, Recombinant Proteins/metabolism, Rumen, Transformation, Genetic, Xylans/metabolism, Xylosidases/genetics/*metabolism	Pathogenicity
Metabolism	23918568	Growth inhibition of hepatocellular carcinoma Huh7 cells by Lactobacillus casei extract.	Han DJ, Kim JB, Park SY, Yang MG, Kim H	Yonsei Med J	10.3349/ymj.2013.54.5.1186	2013	Apoptosis/drug effects, Carcinoma, Hepatocellular/pathology, Caspase 8/metabolism, Caspase 9/metabolism, Cell Cycle Checkpoints/drug effects, Cell Extracts/pharmacology, Cell Line, Tumor, Cell Proliferation/drug effects, Cyclin-Dependent Kinase Inhibitor p21/metabolism, Cyclin-Dependent Kinase Inhibitor p27/metabolism, Cytostatic Agents/pharmacology, Flow Cytometry, Gene Expression Regulation, Neoplastic/drug effects, Humans, Lactobacillus casei/chemistry, Liver Neoplasms/*pathology, Proto-Oncogene Proteins c-bcl-2/metabolism, RNA, Messenger/metabolism, Receptors, Tumor Necrosis Factor, Member 25/metabolism, Receptors, Tumor Necrosis Factor, Type I/metabolism, bcl-Associated Death Protein/metabolism	Pathogenicity
Genetics	24116025	Genomic adaptation of the Lactobacillus casei group.	Toh H, Oshima K, Nakano A, Takahata M, Murakami M, Takaki T, Nishiyama H, Igimi S, Hattori M, Morita H	PLoS One	10.1371/journal.pone.0075073	2013	DNA, Bacterial/genetics, Genome, Bacterial, Genomics, Lactobacillus casei/genetics, Lactobacillus rhamnosus/genetics, Sequence Analysis, DNA	Transcriptome
Enzymology	24191230	16S rRNA PCR-Denaturing Gradient Gel Electrophoresis of Oral Lactobacillus casei Group and Their Phenotypic Appearances.	Piwat S, Teanpaisan R	ISRN Microbiol	10.1155/2013/342082	2013		Phylogeny
Enzymology	24211554	Effective survival of immobilized Lactobacillus casei during ripening and heat treatment of probiotic dry-fermented sausages and investigation of the microbial dynamics.	Sidira M, Karapetsas A, Galanis A, Kanellaki M, Kourkoutas Y	Meat Sci	10.1016/j.meatsci.2013.09.013	2013	Cells, Immobilized, Chemical Phenomena, Colony Count, Microbial, Enterobacteriaceae/isolation & purification, Fermentation, Food Contamination/prevention & control, Food Handling/methods, Food Microbiology, Hot Temperature, Humans, Lactobacillus/isolation & purification, Meat Products/analysis/microbiology, Polymerase Chain Reaction, Probiotics/*metabolism, Pseudomonas/isolation & purification, Staphylococcus/isolation & purification, Taste	Phylogeny
	24657853	Chromosomal insertions in the Lactobacillus casei upp gene that are useful for vaccine expression.	Song BF, Ju LZ, Li YJ, Tang LJ	Appl Environ Microbiol	10.1128/AEM.00175-14	2014	Antigens/genetics/immunology, Bacterial Vaccines/genetics/immunology, Cell Surface Display Techniques, Lactobacillus casei/genetics, Membrane Proteins/genetics/immunology, Molecular Biology/methods, Mutagenesis, Insertional, Plasmids
Genetics	24798148	Construction of upp deletion mutant strains of Lactobacillus casei and Lactococcus lactis based on counterselective system using temperature-sensitive plasmid.	Song L, Cui H, Tang L, Qiao X, Liu M, Jiang Y, Cui W, Li Y	J Microbiol Methods	10.1016/j.mimet.2014.04.011	2014	Chloramphenicol Resistance, DNA Replication, Gene Knockout Techniques, Genetics, Microbial/methods, Lactobacillus casei/genetics, Lactococcus lactis/genetics, Pentosyltransferases/genetics, Plasmids, Recombination, Genetic, Selection, Genetic, Temperature
Biotechnology	24931523	Free and immobilized Lactobacillus casei ATCC 393 on whey protein as starter cultures for probiotic Feta-type cheese production.	Dimitrellou D, Kandylis P, Sidira M, Koutinas AA, Kourkoutas Y	J Dairy Sci	10.3168/jds.2013-7597	2014	Animals, Cells, Immobilized, Cheese/microbiology, Chemical Phenomena, Colony Count, Microbial, Consumer Behavior, Enterobacteriaceae/isolation & purification, Food Handling, Food Microbiology, Gas Chromatography-Mass Spectrometry, Humans, Hydrogen-Ion Concentration, Lactobacillus casei, Microbial Viability, Milk Proteins/metabolism, Principal Component Analysis, *Probiotics, Staphylococcus/isolation & purification, Taste, Volatile Organic Compounds/analysis, Whey Proteins	Enzymology
Biotechnology	25306510	Effect of immobilized Lactobacillus casei on the evolution of flavor compounds in probiotic dry-fermented sausages during ripening.	Sidira M, Kandylis P, Kanellaki M, Kourkoutas Y	Meat Sci	10.1016/j.meatsci.2014.09.011	2014	Alcohols, Animals, Colony Count, Microbial, Esters, Fermentation, Flavoring Agents, Food Handling/methods, Food Microbiology, Gas Chromatography-Mass Spectrometry, Humans, Lactobacillus casei, Meat Products/analysis, Probiotics, Swine, Taste, Triticum/metabolism, Volatile Organic Compounds/*metabolism	Pathogenicity
Metabolism	25447519	C/EBPalpha controls mast cell function.	Kasakura K, Takahashi K, Itoh T, Hosono A, Nunomura S, Ra C, Momose Y, Itoh K, Nishiyama C, Kaminogawa S	FEBS Lett	10.1016/j.febslet.2014.10.036	2014	Animals, Bone Marrow Cells/cytology, CCAAT-Enhancer-Binding Protein-alpha/genetics/metabolism, Cell Differentiation, Chemokine CXCL2/biosynthesis, Female, Gene Expression Regulation, Lactobacillus casei/physiology, Mast Cells/cytology/immunology/*metabolism/microbiology, Mice
Stress	25704702	Effect of immobilized Lactobacillus casei on volatile compounds of heat treated probiotic dry-fermented sausages.	Sidira M, Kandylis P, Kanellaki M, Kourkoutas Y	Food Chem	10.1016/j.foodchem.2015.01.068	2015	Alcohols/analysis, Cells, Immobilized/chemistry, Esters/analysis, Fermentation, Gas Chromatography-Mass Spectrometry/methods, Hot Temperature, Lactobacillus casei, Meat Products/analysis, Probiotics/*analysis, Solid Phase Microextraction/methods, Volatilization
Metabolism	25720152	[Comparison of expression and antibacterial activities of recombinant porcine lactoferrin expressed in four Lactobacillus species].	Yu H, Jiang Y, Cui W, Wu X, He J, Qiao X, Li Y, Tang L	Sheng Wu Gong Cheng Xue Bao		2014	Animals, Anti-Bacterial Agents/biosynthesis, Lactobacillus/metabolism, Lactoferrin/*biosynthesis, Recombinant Proteins/biosynthesis, Swine
Metabolism	26108160	Secretory expression of a phospholipase A2 from Lactobacillus casei DSM20011 in Kluyveromyces lactis.	Wang H, Zhang L, Shi G	J Biosci Bioeng	10.1016/j.jbiosc.2015.03.022	2015	Culture Media/metabolism, Electrophoresis, Polyacrylamide Gel, Galactose/metabolism, Gene Dosage, Gene Expression, Hydrogen-Ion Concentration, Kluyveromyces/genetics/metabolism, Lactobacillus casei/enzymology/genetics, Mating Factor, Molecular Weight, Peptides/genetics/metabolism, Phospholipases A2/biosynthesis/chemistry/genetics/metabolism, Promoter Regions, Genetic, Real-Time Polymerase Chain Reaction, Recombinant Proteins/biosynthesis/chemistry/genetics/metabolism, Temperature	Enzymology
Enzymology	26123178	Isolation and Characterization of a Novel Virulent Phage of Lactobacillus casei ATCC 393.	Zhang X, Lan Y, Jiao W, Li Y, Tang L, Jiang Y, Cui W, Qiao X	Food Environ Virol	10.1007/s12560-015-9206-4	2015	Brassica/microbiology/virology, China, DNA, Viral/chemistry/isolation & purification/metabolism, Fermentation, Food, Preserved/microbiology/virology, Genome, Viral, Hydrogen-Ion Concentration, Kinetics, Lactobacillus casei/virology, Microbial Viability/radiation effects, Microscopy, Electron, Transmission, Plant Leaves/microbiology/virology, Siphoviridae/growth & development/isolation & purification/physiology/ultrastructure, Temperature, Ultraviolet Rays, Virus Physiological Phenomena	Phylogeny
Biotechnology	26142843	Effect of refrigerated storage on probiotic viability and the production and stability of antimutagenic and antioxidant peptides in yogurt supplemented with pineapple peel.	Sah BN, Vasiljevic T, McKechnie S, Donkor ON	J Dairy Sci	10.3168/jds.2015-9450	2015	Ananas/chemistry, Antimutagenic Agents/pharmacology, Antioxidants/pharmacology, Food Microbiology, Food Storage, Food, Fortified, Inulin/chemistry, Lactobacillus acidophilus/metabolism, Lactobacillus casei/metabolism, Microbial Viability, Peptides/pharmacology, Prebiotics, Probiotics, Proteolysis, Refrigeration, Yogurt/analysis	Metabolism
	26344983	Use of Pistacia terebinthus resin as immobilization support for Lactobacillus casei cells and application in selected dairy products.	Schoina V, Terpou A, Angelika-Ioanna G, Koutinas A, Kanellaki M, Bosnea L	J Food Sci Technol	10.1007/s13197-014-1627-9	2014
Stress	26782045	Investigation of Shelf Life of Potency and Activity of the Lactobacilli Produced Bacteriocins Through Their Exposure to Various Physicochemical Stress Factors.	Zacharof MP, Lovitt RW	Probiotics Antimicrob Proteins	10.1007/s12602-012-9102-2	2012
Metabolism	26849051	Lactobacillus casei Exerts Anti-Proliferative Effects Accompanied by Apoptotic Cell Death and Up-Regulation of TRAIL in Colon Carcinoma Cells.	Tiptiri-Kourpeti A, Spyridopoulou K, Santarmaki V, Aindelis G, Tompoulidou E, Lamprianidou EE, Saxami G, Ypsilantis P, Lampri ES, Simopoulos C, Kotsianidis I, Galanis A, Kourkoutas Y, Dimitrellou D, Chlichlia K	PLoS One	10.1371/journal.pone.0147960	2016	Animals, Apoptosis, Bacterial Adhesion, Cell Line, Tumor, Cell Proliferation, Cell Survival, Colonic Neoplasms/genetics/metabolism, Cyclin D1/genetics/metabolism, Disease Models, Animal, Female, Gene Expression Regulation, Neoplastic, Heterografts, Humans, Hydrogen-Ion Concentration, Inhibitor of Apoptosis Proteins/genetics/metabolism, Lactobacillus casei/physiology, Mice, Probiotics, Survivin, TNF-Related Apoptosis-Inducing Ligand/genetics/metabolism, Up-Regulation	Pathogenicity
	26868585	Effect of curing salts and probiotic cultures on the evolution of flavor compounds in dry-fermented sausages during ripening.	Sidira M, Kandylis P, Kanellaki M, Kourkoutas Y	Food Chem	10.1016/j.foodchem.2016.01.084	2016	Fermentation, Gas Chromatography-Mass Spectrometry/methods, Meat Products/analysis, Probiotics/analysis, Salts/chemistry
Pathogenicity	27018325	Effect of oligosaccharides on the adhesion of gut bacteria to human HT-29 cells.	Altamimi M, Abdelhay O, Rastall RA	Anaerobe	10.1016/j.anaerobe.2016.03.010	2016	Bacterial Adhesion/drug effects, Bacteroides/drug effects/physiology, Bacteroides fragilis/drug effects/physiology, Bifidobacterium/drug effects/physiology, Clostridium/drug effects/physiology, Faecalibacterium/drug effects/physiology, Gastrointestinal Microbiome/drug effects, HT29 Cells, Humans, Lactobacillus casei/drug effects/physiology, Mucins/metabolism, Oligosaccharides/pharmacology, Prebiotics/analysis, Species Specificity	Phylogeny
	27066007	Orally Administered Salacia reticulata Extract Reduces H1N1 Influenza Clinical Symptoms in Murine Lung Tissues Putatively Due to Enhanced Natural Killer Cell Activity.	Romero-Perez GA, Egashira M, Harada Y, Tsuruta T, Oda Y, Ueda F, Tsukahara T, Tsukamoto Y, Inoue R	Front Immunol	10.3389/fimmu.2016.00115	2016
	27557715	Directed chromosomal integration and expression of porcine rotavirus outer capsid protein VP4 in Lactobacillus casei ATCC393.	Yin JY, Guo CQ, Wang Z, Yu ML, Gao S, Bukhari SM, Tang LJ, Xu YG, Li YJ	Appl Microbiol Biotechnol	10.1007/s00253-016-7779-y	2016	Administration, Oral, Animals, Capsid Proteins/biosynthesis/genetics, Gene Expression, Gene Targeting/methods, Genomic Instability, Lactobacillus casei/genetics, Mice, Inbred BALB C, Recombinant Proteins/biosynthesis/genetics, Recombination, Genetic, Rotavirus Vaccines/administration & dosage/genetics/immunology, Vaccines, Synthetic/administration & dosage/genetics/immunology
Metabolism	27653426	Lactobacillus pentosus expressing porcine lactoferrin elevates antibacterial activity and improves the efficacy of vaccination against Aujeszky's disease.	Xu Y, Zong X, Han B, Li Y, Tang L	Acta Vet Hung	10.1556/004.2016.028	2016	Animals, Antibodies, Bacterial/blood, Bacterial Vaccines/immunology, Immunoglobulin G/blood, Lactobacillus pentosus/metabolism, Lactoferrin/metabolism, Mice, Pseudorabies/blood/prevention & control, Recombinant Proteins, Swine, Vaccination
Pathogenicity	27904056	Prophylactic Effect of Lactobacillus pentosus strain S-PT84 on Candida Infection and Gastric Inflammation in a Murine Gastrointestinal Candidiasis Model.	Maekawa T, Ishijima AS, Ida M, Izumo T, Ono Y, Shibata H, Abe S	Med Mycol J	10.3314/mmj.16-00012	2016	Administration, Oral, Animals, Antibiosis, Candida albicans/growth & development, Candidiasis/prevention & control, Capillary Permeability, Disease Models, Animal, Female, Gastrointestinal Diseases/prevention & control, Inflammation/prevention & control, Lactobacillus pentosus, Mice, Inbred ICR, Neutrophil Infiltration, Probiotics/administration & dosage, Severity of Illness Index, Stomach/microbiology
Pathogenicity	27904074	Prophylactic Effect of Lactobacillus pentosus strain S-PT84 on Candida Infection and Gastric Inflammation in a Murine Gastrointestinal Candidiasis Model [Errata].	Maekawa T, Ishijima AS, Ida M, Izumo T, Ono Y, Shibata H, Abe S	Med Mycol J	10.3314/mmj.16-00012E	2016	Administration, Oral, Animals, Antibiosis, Candida albicans/growth & development, Candidiasis/prevention & control, Capillary Permeability, Disease Models, Animal, Female, Gastrointestinal Diseases/prevention & control, Inflammation/prevention & control, Lactobacillus pentosus, Mice, Inbred ICR, Neutrophil Infiltration, Probiotics/administration & dosage, Severity of Illness Index, Stomach/microbiology
Pathogenicity	28316010	Protective Effect of Lactobacillus casei on DMH-Induced Colon Carcinogenesis in Mice.	Irecta-Najera CA, Del Rosario Huizar-Lopez M, Casas-Solis J, Castro-Felix P, Santerre A	Probiotics Antimicrob Proteins	10.1007/s12602-017-9253-2	2017	Animals, Carcinogenesis, Colon/drug effects/metabolism/microbiology, Colonic Neoplasms/etiology/metabolism/prevention & control, Dimethylhydrazines/toxicity, Female, Humans, Lactobacillus casei/genetics/physiology, Mice, Polyamines/metabolism, Probiotics/administration & dosage	Metabolism
Enzymology	28401477	A Recombinant Probiotic, Lactobacillus casei, Expressing the Clostridium perfringens alpha-toxoid, as an Orally Vaccine Candidate Against Gas Gangrene and Necrotic Enteritis.	Alimolaei M, Golchin M, Abshenas J, Ezatkhah M, Bafti MS	Probiotics Antimicrob Proteins	10.1007/s12602-017-9276-8	2018	Administration, Oral, Animals, Antibodies, Bacterial/immunology, Bacterial Vaccines/administration & dosage/genetics/immunology, Cloning, Molecular, Clostridium perfringens/genetics/immunology, Enteritis/immunology/prevention & control, Female, Gas Gangrene/immunology/prevention & control, Gene Expression, Humans, Immunization, Lactobacillus casei/genetics/immunology, Mice, Mice, Inbred BALB C, Probiotics/administration & dosage, Toxoids/*administration & dosage/genetics/immunology	Pathogenicity
	28455035	In vitro study on the cell adhesion ability of immobilized lactobacilli on natural supports.	Sidira M, Kourkoutas Y, Kanellaki M, Charalampopoulos D	Food Res Int	10.1016/j.foodres.2015.07.036	2015
Metabolism	28625525	Recombinant Lactobacillus casei expressing Clostridium perfringens toxoids alpha, beta2, epsilon and beta1 gives protection against Clostridium perfringens in rabbits.	Zhao L, Guo Z, Liu J, Wang Z, Wang R, Li Y, Wang L, Xu Y, Tang L, Qiao X	Vaccine	10.1016/j.vaccine.2017.05.076	2017	Administration, Oral, Animals, Antibodies, Bacterial/blood, Bacterial Vaccines/administration & dosage/genetics/immunology, Clostridium Infections/prevention & control, Disease Models, Animal, Drug Carriers, Enzyme-Linked Immunosorbent Assay, Female, Immunoglobulin A, Secretory/analysis, Immunoglobulin G/blood, Interferon-gamma/metabolism, Interleukin-4/metabolism, Lactobacillus casei/genetics/immunology, Lymphocytes/immunology, Rabbits, Toxoids/genetics/*immunology, Vaccines, Synthetic/administration & dosage/genetics/immunology
	28873648	Soybean protein-based microparticles for oral delivery of probiotics with improved stability during storage and gut resistance.	Gonzalez-Ferrero C, Irache JM, Gonzalez-Navarro CJ	Food Chem	10.1016/j.foodchem.2017.07.022	2017	Animals, Desiccation, Drug Storage, Intestines, Lactobacillus plantarum, Microbial Viability, Milk, Probiotics, Soybean Proteins/*chemistry
Pathogenicity	29316223	Probiotic Lactobacillus sp. inhibit growth, biofilm formation and gene expression of caries-inducing Streptococcus mutans.	Wasfi R, Abd El-Rahman OA, Zafer MM, Ashour HM	J Cell Mol Med	10.1111/jcmm.13496	2018	Antibiosis, Bacteriocins/pharmacology, Biofilms/drug effects/growth & development, Catalase/pharmacology, Culture Media/chemistry, Humans, Hydrogen-Ion Concentration, Interferon-gamma/biosynthesis, Interleukin-10/biosynthesis, Lactobacillus casei/drug effects/growth & development/metabolism, Lactobacillus plantarum/drug effects/growth & development/metabolism, Lactobacillus reuteri/drug effects/growth & development/metabolism, Lactobacillus salivarius/drug effects/growth & development/metabolism, Leukocytes, Mononuclear/cytology/immunology/microbiology, Microbial Sensitivity Tests, Peroxides/pharmacology, Polysaccharides, Bacterial/antagonists & inhibitors/biosynthesis, Primary Cell Culture, Probiotics/pharmacology, Quorum Sensing/drug effects, Streptococcus mutans/*drug effects/genetics/growth & development/pathogenicity, Trypsin/pharmacology	Metabolism
Metabolism	29744632	Adsorption preference for divalent metal ions by Lactobacillus casei JCM1134.	Endo R, Aoyagi H	Appl Microbiol Biotechnol	10.1007/s00253-018-9050-1	2018	Adsorption, Cadmium, Cations, Divalent/metabolism, Copper, Hydrogen-Ion Concentration, Ion Exchange, Kinetics, Lactobacillus casei/growth & development/metabolism, Metals/*metabolism, Water Pollutants, Chemical, Water Purification	Enzymology
Pathogenicity	29805014	Preparation, characteristics and antioxidant activity of polysaccharides and proteins-capped selenium nanoparticles synthesized by Lactobacillus casei ATCC 393.	Xu C, Qiao L, Guo Y, Ma L, Cheng Y	Carbohydr Polym	10.1016/j.carbpol.2018.04.110	2018	Antineoplastic Agents/chemistry/pharmacology, Antioxidants/chemistry/pharmacology, Apoptosis/drug effects, Bacterial Proteins/chemistry, Cell Line, Hep G2 Cells, Humans, Lactobacillus casei/chemistry/metabolism, Nanoparticles/chemistry, Polysaccharides, Bacterial/chemistry, Selenium/chemistry	Metabolism
	29967593	Biogenic Synthesis of Novel Functionalized Selenium Nanoparticles by Lactobacillus casei ATCC 393 and Its Protective Effects on Intestinal Barrier Dysfunction Caused by Enterotoxigenic Escherichia coli K88.	Xu C, Guo Y, Qiao L, Ma L, Cheng Y, Roman A	Front Microbiol	10.3389/fmicb.2018.01129	2018
Metabolism	30055567	Construction of Lactobacillus casei ghosts by Holin-mediated inactivation and the potential as a safe and effective vehicle for the delivery of DNA vaccines.	Hou R, Li M, Tang T, Wang R, Li Y, Xu Y, Tang L, Wang L, Liu M, Jiang Y, Cui W, Qiao X	BMC Microbiol	10.1186/s12866-018-1216-6	2018	Bacteriophages/genetics, Cell Membrane/metabolism/ultrastructure, DNA/administration & dosage/genetics/metabolism, Drug Delivery Systems, Gene Expression, Genetic Vectors, Lactobacillus casei/physiology/ultrastructure/virology, Plasmids/genetics/metabolism, Recombinant Proteins/genetics/metabolism, Vaccines, DNA/administration & dosage/genetics/metabolism, Viral Proteins/genetics/metabolism	Pathogenicity
Pathogenicity	30353740	Lactobacillus paracasei K5 displays adhesion, anti-proliferative activity and apoptotic effects in human colon cancer cells.	Chondrou P, Karapetsas A, Kiousi DE, Tsela D, Tiptiri-Kourpeti A, Anestopoulos I, Kotsianidis I, Bezirtzoglou E, Pappa A, Galanis A	Benef Microbes	10.3920/BM2017.0183	2018	Antineoplastic Agents/administration & dosage/pharmacology, Apoptosis, Bacterial Adhesion, Caco-2 Cells, Cell Proliferation/drug effects, Colonic Neoplasms/drug therapy, Humans, Lactobacillus rhamnosus/physiology, Microscopy, Confocal, Microscopy, Fluorescence, Models, Theoretical, Probiotics/administration & dosage/pharmacology
	30425707	Genetic Signatures of Dairy Lactobacillus casei Group.	Fontana A, Zacconi C, Morelli L	Front Microbiol	10.3389/fmicb.2018.02611	2018
Metabolism	30890726	Estimation of microbial phosphate-accumulation abilities.	Anand A, Aoyagi H	Sci Rep	10.1038/s41598-018-37752-8	2019	Bifidobacterium adolescentis/drug effects/metabolism, Cell-Free System, Gastrointestinal Microbiome/drug effects, Humans, Hyperphosphatemia/drug therapy/metabolism/pathology, Lactobacillus casei/drug effects/metabolism, Phosphate-Binding Proteins/metabolism, Phosphates/adverse effects/metabolism, Probiotics/isolation & purification/metabolism, Renal Dialysis/adverse effects	Pathogenicity
	31234282	Effect of Sugar Content on Quality Characteristics and Shelf-Life of Probiotic Dry-Fermented Sausages Produced by Free or Immobilized Lactobacillus casei ATCC 393.	Sidira M, Mitropoulou G, Galanis A, Kanellaki M, Kourkoutas Y	Foods	10.3390/foods8060219	2019
	31388208	Recombinant l-Asparaginase II from Lactobacillus casei subsp. casei ATCC 393 and Its Anticancer Activity.	Aishwarya SS, Selvarajan E, Iyappan S, Rajnish KN	Indian J Microbiol	10.1007/s12088-019-00806-0	2019
Pathogenicity	31417254	Biogenic selenium nanoparticles synthesized by Lactobacillus casei ATCC 393 alleviate intestinal epithelial barrier dysfunction caused by oxidative stress via Nrf2 signaling-mediated mitochondrial pathway.	Xu C, Qiao L, Ma L, Guo Y, Dou X, Yan S, Zhang B, Roman A	Int J Nanomedicine	10.2147/IJN.S199193	2019	Animals, Antioxidants/pharmacology, Cell Line, Cell Membrane Permeability/drug effects, Cell Survival/drug effects, Humans, Hydrogen Peroxide/toxicity, Intestinal Mucosa/drug effects/pathology/physiopathology, Lactobacillus casei/metabolism, Membrane Potential, Mitochondrial/drug effects, Mitochondria/drug effects/metabolism/ultrastructure, Models, Biological, NF-E2-Related Factor 2/metabolism, Nanoparticles/chemistry/ultrastructure, Oxidation-Reduction, Oxidative Stress/drug effects, Protective Agents/pharmacology, Selenium/pharmacology, Signal Transduction/drug effects, Swine	Metabolism
	31438455	Effect of Milk Type on the Microbiological, Physicochemical and Sensory Characteristics of Probiotic Fermented Milk.	Dimitrellou D, Salamoura C, Kontogianni A, Katsipi D, Kandylis P, Zakynthinos G, Varzakas T	Microorganisms	10.3390/microorganisms7090274	2019
	31480583	Assessment of Freeze-Dried Immobilized Lactobacillus casei as Probiotic Adjunct Culture in Yogurts.	Dimitrellou D, Kandylis P, Kourkoutas Y	Foods	10.3390/foods8090374	2019
Metabolism	31667575	Exploring encapsulation strategies as a protective mechanism to avoid amensalism in mixed populations of Pseudomonas taetrolens and Lactobacillus casei.	Garcia C, Ranieri G, Rendueles M, Diaz M	Bioprocess Biosyst Eng	10.1007/s00449-019-02204-8	2019	Cells, Immobilized/cytology/metabolism, Disaccharides/biosynthesis, Lactobacillus casei/cytology/metabolism, Pseudomonas/cytology/metabolism
Cultivation	31741312	Topical Delivery of Lactobacillus Culture Supernatant Increases Survival and Wound Resolution in Traumatic Acinetobacter baumannii Infections.	Stanbro J, Park JM, Bond M, Stockelman MG, Simons MP, Watters C	Probiotics Antimicrob Proteins	10.1007/s12602-019-09603-z	2020	Acinetobacter Infections/therapy, Acinetobacter baumannii, Animals, Anti-Bacterial Agents/therapeutic use, Biofilms, Culture Media, Conditioned/pharmacology, Female, Lactobacillus, Mice, Mice, Inbred BALB C, Probiotics/therapeutic use
Phylogeny	31792245	A High Throughput Isolation Method for Phosphate-Accumulating Organisms.	Anand A, Aoyagi H	Sci Rep	10.1038/s41598-019-53429-2	2019	Bifidobacterium adolescentis/isolation & purification/metabolism, Cell Culture Techniques, Centrifugation, Density Gradient, Humans, Hyperphosphatemia/metabolism/therapy, Lactobacillus casei/isolation & purification/metabolism, Phosphates/isolation & purification/metabolism, Probiotics/isolation & purification/metabolism	Metabolism
	31877900	Enhanced Aromatic Profile and Functionality of Cheese Whey Beverages by Incorporation of Probiotic Cells Immobilized on Pistacia terebinthus Resin.	Schoina V, Terpou A, Papadaki A, Bosnea L, Kopsahelis N, Kanellaki M	Foods	10.3390/foods9010013	2019
Metabolism	31926249	Lactobacillus casei ATCC 393 alleviates Enterotoxigenic Escherichia coli K88-induced intestinal barrier dysfunction via TLRs/mast cells pathway.	Xu C, Yan S, Guo Y, Qiao L, Ma L, Dou X, Zhang B	Life Sci	10.1016/j.lfs.2020.117281	2020	Animals, Cell Line, Cell Survival, Enterotoxigenic Escherichia coli/metabolism/pathogenicity, Epithelial Cells/metabolism, Escherichia coli Infections/metabolism, Gastrointestinal Diseases/metabolism, Intestinal Diseases/metabolism, Intestinal Mucosa/metabolism, Intestines/physiology, Lactobacillus casei/metabolism, Male, Mast Cells/metabolism/*physiology, Mice, Mice, Inbred C57BL, Models, Animal, Swine, Toll-Like Receptors/metabolism	Pathogenicity
	32080981	Polymeric Films for the Encapsulation, Storage, and Tunable Release of Therapeutic Microbes.	Qiu K, Young I, Woodburn BM, Huang Y, Anselmo AC	Adv Healthc Mater	10.1002/adhm.201901643	2020	Capsules, Drug Delivery Systems, Excipients, Polymers
Pathogenicity	32243488	Biogenic selenium nanoparticles synthesized by Lactobacillus casei ATCC 393 alleviate diquat-induced intestinal barrier dysfunction in C57BL/6 mice through their antioxidant activity.	Qiao L, Dou X, Yan S, Zhang B, Xu C	Food Funct	10.1039/d0fo00132e	2020	Animals, Antioxidants/administration & dosage/chemistry/pharmacology, Dietary Supplements, Diquat, Disease Models, Animal, Functional Food, Inflammatory Bowel Diseases/chemically induced/prevention & control, Lactobacillus casei, Male, Mice, Mice, Inbred C57BL, Nanoparticles, Oxidative Stress/drug effects, Random Allocation, Selenium/*administration & dosage/chemistry/pharmacology
Phylogeny	32421490	Genome-based reclassification of Lactobacillus casei: emended classification and description of the species Lactobacillus zeae.	Huang CH, Chen CC, Liou JS, Lee AY, Blom J, Lin YC, Huang L, Watanabe K	Int J Syst Evol Microbiol	10.1099/ijsem.0.003969	2020	Bacterial Typing Techniques, Base Composition, DNA, Bacterial/genetics, Fatty Acids/chemistry, Genes, Bacterial, Lactobacillus/classification, Lactobacillus casei/classification, Multilocus Sequence Typing, Nucleic Acid Hybridization, *Phylogeny, RNA, Ribosomal, 16S/genetics, Sequence Analysis, DNA	Transcriptome
	33711368	Microencapsulation of Lactobacillus casei and Lactobacillus rhamnosus in pectin and pectin-inulin microgel particles: Effect on bacterial survival under storage conditions.	Tarifa MC, Piqueras CM, Genovese DB, Brugnoni LI	Int J Biol Macromol	10.1016/j.ijbiomac.2021.03.038	2021	Capsules/chemistry, Inulin/chemistry, Lactobacillus casei/growth & development, Lactobacillus rhamnosus/growth & development, Microbial Viability, Microgels/chemistry, Pectins/chemistry
	34047549	Encapsulation of Lactobacillus in Low-Methoxyl Pectin-Based Microcapsules Stimulates Biofilm Formation: Enhanced Resistances to Heat Shock and Simulated Gastrointestinal Digestion.	He C, Sampers I, Van de Walle D, Dewettinck K, Raes K	J Agric Food Chem	10.1021/acs.jafc.1c00719	2021	Biofilms, Capsules, Digestion, Heat-Shock Response, Pectins, Probiotics
Pathogenicity	34156041	Biogenic selenium nanoparticles by Lactobacillus casei ATCC 393 alleviate the intestinal permeability, mitochondrial dysfunction and mitophagy induced by oxidative stress.	Yan S, Qiao L, Dou X, Song X, Chen Y, Zhang B, Xu C	Food Funct	10.1039/d0fo03141k	2021	Animals, Cell Line, Intestinal Absorption/drug effects, Lactobacillus casei/metabolism, Metal Nanoparticles/chemistry, Mitochondria/drug effects/pathology, Mitophagy/drug effects, Oxidative Stress/drug effects, *Selenium/chemistry/pharmacology, Swine	Stress
	34372508	Oral Immunization with Lactobacillus casei Expressing the Porcine Circovirus Type 2 Cap and LTB Induces Mucosal and Systemic Antibody Responses in Mice.	Li F, Wang X, Ma R, Wu W, Teng F, Cheng X, Jiang Y, Zhou H, Wang L, Tang L, Qiao X, Li Y	Viruses	10.3390/v13071302	2021	Administration, Oral, Animals, Antibodies, Viral/blood, Antibody Formation, Capsid Proteins/administration & dosage/genetics/immunology, Circovirus/genetics, Immunity, Mucosal, Immunization/methods, Lactobacillus casei/genetics/*immunology, Mice, Mice, Inbred BALB C, Recombinant Proteins, Swine, Vaccine Development/methods
Pathogenicity	34389737	Tailored synbiotic powder (functional food) to prevent hyperphosphataemia (kidney disorder).	Anand A, Yoshida S, Aoyagi H	Sci Rep	10.1038/s41598-021-95176-3	2021	Aloe, Drug Compounding, Humans, Hyperphosphatemia/prevention & control, In Vitro Techniques, Intestinal Mucosa/metabolism, Kidney Diseases/prevention & control, Lactobacillus casei/ultrastructure, Lysine, Microscopy, Electron, Scanning, Phosphates/metabolism, *Synbiotics	Metabolism
	34577129	Development and Optimization of Djulis Sourdough Bread Fermented by Lactic Acid Bacteria for Antioxidant Capacity.	Chen HY, Hsieh CW, Chen PC, Lin SP, Lin YF, Cheng KC	Molecules	10.3390/molecules26185658	2021	Antioxidants, Bread, Fermentation, *Flour, Lactobacillales
Phylogeny	34604450	Isolation and Characterization of Membrane Vesicles from Lactobacillus Species.	Caruana JC, Dean SN, Walper SA	Bio Protoc	10.21769/BioProtoc.4145	2021
	34676502	Alterations in Faecal Microbiota and Elevated Levels of Intestinal IgA Following Oral Administration of Lacticaseibacillus casei in mice.	Aindelis G, Ypsilantis P, Chlichlia K	Probiotics Antimicrob Proteins	10.1007/s12602-021-09864-7	2021
Metabolism	34755743	Lactobacillus casei ATCC 393 and it's metabolites alleviate dextran sulphate sodium-induced ulcerative colitis in mice through the NLRP3-(Caspase-1)/IL-1beta pathway.	Dou X, Qiao L, Chang J, Yan S, Song X, Chen Y, Xu Q, Xu C	Food Funct	10.1039/d1fo02405a	2021	Animals, Caspase 1/metabolism, Colitis, Ulcerative/chemically induced/metabolism, Dextran Sulfate/adverse effects, Disease Models, Animal, Gastrointestinal Diseases, Interleukin-1beta/metabolism, Lactobacillus casei, Male, Mice, Mice, Inbred C57BL, NLR Family, Pyrin Domain-Containing 3 Protein/metabolism, Probiotics/*pharmacology, Signal Transduction/drug effects	Pathogenicity
	34771499	Anticancer Activity of Biogenic Selenium Nanoparticles: Apoptotic and Immunogenic Cell Death Markers in Colon Cancer Cells.	Spyridopoulou K, Aindelis G, Pappa A, Chlichlia K	Cancers (Basel)	10.3390/cancers13215335	2021
	34777606	Polymer and Crosslinker Content Influences Performance of Encapsulated Live Biotherapeutic Products.	Qiu K, Huang Y, Anselmo AC	Cell Mol Bioeng	10.1007/s12195-021-00674-z	2021
Metabolism	34899686	The Role of Vasoactive Intestinal Peptide and Mast Cells in the Regulatory Effect of Lactobacillus casei ATCC 393 on Intestinal Mucosal Immune Barrier.	Song X, Pi S, Gao Y, Zhou F, Yan S, Chen Y, Qiao L, Dou X, Shao D, Xu C	Front Immunol	10.3389/fimmu.2021.723173	2021	Animals, Coculture Techniques, Enterotoxigenic Escherichia coli, Gastrointestinal Microbiome/physiology, Intestinal Mucosa/metabolism/microbiology, Lactobacillus casei, Mast Cells/metabolism, Mice, Mice, Inbred C57BL, Swine, Vasoactive Intestinal Peptide/*metabolism
	34946147	Lacticaseibacillus casei ATCC 393 Cannot Colonize the Gastrointestinal Tract of Crucian Carp.	Zhang H, Mu X, Wang H, Wang H, Wang H, Li Y, Mu Y, Song J, Xia L	Microorganisms	10.3390/microorganisms9122547	2021
	35335620	Antiparasitic Action of Lactobacillus casei ATCC 393 and Lactobacillus paracasei CNCM Strains in CD-1 Mice Experimentally Infected with Trichinella britovi.	Boros Z, Baies MH, Vodnar DC, Gherman CM, Borsan SD, Cozma-Petrut A, Lefkaditis M, Gyorke A, Cozma V	Pathogens	10.3390/pathogens11030296	2022
	35632632	Evaluation of the Immunogenicity in Mice Orally Immunized with Recombinant Lactobacillus casei Expressing Porcine Epidemic Diarrhea Virus S1 Protein.	Xiao Y, Wang X, Li Y, Li F, Zhao H, Shao Y, Zhang L, Ding G, Li J, Jiang Y, Cui W, Shan Z, Zhou H, Wang L, Qiao X, Tang L, Li Y	Viruses	10.3390/v14050890	2022	Animals, Antibodies, Viral, Coronavirus Infections/prevention & control/veterinary, Diarrhea, Lactobacillus casei, Mice, Porcine epidemic diarrhea virus/genetics, Swine, Viral Vaccines
	36134160	Biogenic selenium nanoparticles produced by Lactobacillus casei ATCC 393 inhibit colon cancer cell growth in vitro and in vivo.	Spyridopoulou K, Tryfonopoulou E, Aindelis G, Ypsilantis P, Sarafidis C, Kalogirou O, Chlichlia K	Nanoscale Adv	10.1039/d0na00984a	2021
Metabolism	36246933	Selenium Nanoparticles-Enriched Lactobacillus casei ATCC 393 Prevents Cognitive Dysfunction in Mice Through Modulating Microbiota-Gut-Brain Axis.	Qiao L, Chen Y, Song X, Dou X, Xu C	Int J Nanomedicine	10.2147/IJN.S374024	2022	Aluminum Chloride/pharmacology, Amyloid beta-Peptides/metabolism, Animals, Antioxidants/pharmacology, Brain-Derived Neurotrophic Factor/metabolism, Brain-Gut Axis, Cognitive Dysfunction/prevention & control, Food Additives, Galactose, Gastrointestinal Microbiome, Lacticaseibacillus casei/metabolism, Mice, Nanoparticles/chemistry, Neurodegenerative Diseases, Proto-Oncogene Proteins c-akt/metabolism, RNA, Ribosomal, 16S, Selenium/metabolism/pharmacology, tau Proteins/metabolism	Phylogeny
Metabolism	36371888	Dietary supplementation with selenium nanoparticles-enriched Lactobacillus casei ATCC 393 alleviates intestinal barrier dysfunction of mice exposed to deoxynivalenol by regulating endoplasmic reticulum stress and gut microbiota.	Song X, Qiao L, Chang J, Dou X, Zhang X, Pi S, Xu C	Ecotoxicol Environ Saf	10.1016/j.ecoenv.2022.114276	2022	Humans, Mice, Animals, Gastrointestinal Microbiome, Lacticaseibacillus casei/genetics/metabolism, Selenium/pharmacology/metabolism, Endoplasmic Reticulum Stress, Mice, Inbred C57BL, Fatty Acids, Volatile/metabolism, Nanoparticles, RNA, Messenger/metabolism, Dietary Supplements	Pathogenicity
	36435923	Biogenic Selenium Nanoparticles Attenuate Abeta(25-35)-Induced Toxicity in PC12 Cells via Akt/CREB/BDNF Signaling Pathway.	Qiao L, Chen Y, Dou X, Song X, Xu C	Neurotox Res	10.1007/s12640-022-00590-8	2022
	36469280	Biogenic Selenium Nanoparticles Synthesized by Lactobacillus casei ATCC 393 Alleviate Acute Hypobaric Hypoxia-Induced Intestinal Barrier Dysfunction in C57BL/6 Mice.	Dou X, Zhang B, Qiao L, Song X, Pi S, Chang J, Zhang X, Zeng X, Zhu L, Xu C	Biol Trace Elem Res	10.1007/s12011-022-03513-y	2022

Reference

@id	authors	catalogue	doi/url	title	journal	pubmed
8425	Curators of the DSMZ	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 20011)	https://www.dsmz.de/collection/catalogue/details/culture/DSM-20011
20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.		10.1099/ijsem.0.004332	List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ
20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.		10.1016/j.syapm.2013.11.002	StrainInfo introduces electronic passports for microorganisms.	Syst Appl Microbiol. 37: 42-50 2014	24321274
22930	Evelia Acedo-Félix, Gaspar Pérez-Martínez		10.1099/ijs.0.02325-0	Significant differences between Lactobacillus casei subsp. casei ATCC 393T and a commonly used plasmid-cured derivative revealed by a polyphasic study	IJSEM 53: 67-75 2003	12656154
41833	Curators of the CIP		https://brclims.pasteur.fr/brcWeb/souche/detail/1/14902
47412	Curators of the CCUG	Culture Collection University of Gothenburg (CCUG) (CCUG 21451)	https://www.ccug.se/strain?id=21451
66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann		https://diaspora-project.de/progress.html#genomes	Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)
67770	Curators of the JCM		https://jcm.brc.riken.jp/en/
68371				Automatically annotated from API 50CH acid
68379				Automatically annotated from API Coryne
68382				Automatically annotated from API zym
69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.		https://microbeatlas.org/	MicrobeAtlas 1.0 beta
69480	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann		https://diaspora-project.de/progress.html#genomes	Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)
69481	Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch		10.21203/rs.3.rs-2527258/v1	Predictions based on the model GenomeNet Sporulation v. 1
76030	Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.		10.60712/SI-ID9751.1	StrainInfo: A central database for resolving microbial strain identifiers
117199	Curators of the CIP	Collection of Institut Pasteur (CIP 103137)	https://catalogue-crbip.pasteur.fr/fiche_catalogue.xhtml?crbip=CIP%20103137

General

NCBI tax id

strain history

Name and taxonomic classification

LPSN

synonyms

Morphology

cell morphology

Culture and growth conditions

culture medium

culture temp

Physiology and metabolism

oxygen tolerance

spore formation

compound production

murein

metabolite utilization

metabolite tests

enzymes

API coryne

API zym

API 50CHac

Isolation, sampling and environmental information

isolation

isolation source categories

taxonmaps

Safety information

risk assessment

Sequence information

16S sequences

Genome sequences

GC content

Genome-based predictions

predictions

External links

straininfo link

literature

Reference