Strain identifier
BacDive ID: 650
Type strain: 
Species: Heyndrickxia coagulans
Strain Designation: M-39
Strain history: IAM 12320 <-- O. Nakayama M-39 ("Bacillus racemilacticus").
NCBI tax ID(s): 1398 (species)
version 8.1 (current version)
General
@ref: 1042
BacDive-ID: 650
DSM-Number: 2314
keywords: genome sequence, Bacteria, spore-forming, thermophilic, Gram-positive, lactate production, human pathogen
description: Heyndrickxia coagulans M-39 is a spore-forming, thermophilic, Gram-positive human pathogen that produces lactate and was isolated from rhizosphere.
NCBI tax id
- NCBI tax id: 1398
- Matching level: species
strain history
| @ref | history |
|---|---|
| 1042 | <- NCIB <- O. Nakayama, M-39 (Bacillus racemilacticus) |
| 67770 | IAM 12320 <-- O. Nakayama M-39 ("Bacillus racemilacticus"). |
doi: 10.13145/bacdive650.20230509.8.1
Name and taxonomic classification
LPSN
- @ref: 20215
- description: domain/bacteria
- keyword: phylum/bacillota
- domain: Bacteria
- phylum: Bacillota
- class: Bacilli
- order: Caryophanales
- family: Bacillaceae
- genus: Heyndrickxia
- species: Heyndrickxia coagulans
- full scientific name: Heyndrickxia coagulans (Hammer 1915) Narsing Rao et al. 2023
synonyms
@ref synonym 20215 Bacillus coagulans 20215 Weizmannia coagulans
@ref: 1042
domain: Bacteria
phylum: Firmicutes
class: Bacilli
order: Bacillales
family: Bacillaceae
genus: Weizmannia
species: Weizmannia coagulans
full scientific name: Weizmannia coagulans (Hammer 1915) Gupta et al. 2020
strain designation: M-39
type strain: no
Morphology
cell morphology
- @ref: 69480
- gram stain: positive
- confidence: 100
Culture and growth conditions
culture medium
| @ref | name | growth | link | composition |
|---|---|---|---|---|
| 1042 | CASO AGAR (MERCK 105458) (DSMZ Medium 220) | yes | https://mediadive.dsmz.de/medium/220 | Name: CASO AGAR (Merck 105458) (DSMZ Medium 220) Composition: Agar 15.0 g/l Casein peptone 15.0 g/l NaCl 5.0 g/l Soy peptone 5.0 g/l Distilled water |
| 1042 | NUTRIENT AGAR (DSMZ Medium 1) | yes | https://mediadive.dsmz.de/medium/1 | Name: NUTRIENT AGAR (DSMZ Medium 1) Composition: Agar 15.0 g/l Peptone 5.0 g/l Meat extract 3.0 g/l Distilled water |
culture temp
| @ref | growth | type | temperature | range |
|---|---|---|---|---|
| 1042 | positive | growth | 55 | thermophilic |
| 67770 | positive | growth | 30 | mesophilic |
Physiology and metabolism
spore formation
| @ref | spore formation | confidence |
|---|---|---|
| 69481 | yes | 95 |
| 69480 | yes | 100 |
compound production
| @ref | compound |
|---|---|
| 1042 | L(+) lactic acid |
| 1042 | DL lactic acid |
Isolation, sampling and environmental information
isolation
| @ref | sample type | geographic location | country | origin.country | continent |
|---|---|---|---|---|---|
| 1042 | rhizosphere | ||||
| 67770 | Soil | Kofu, Yamanashi Pref. | Japan | JPN | Asia |
isolation source categories
- Cat1: #Host Body-Site
- Cat2: #Plant
- Cat3: #Rhizosphere
Safety information
risk assessment
- @ref: 1042
- pathogenicity human: yes, in single cases
- biosafety level: 1
- biosafety level comment: Risk group (German classification)
Sequence information
Genome sequences
| @ref | description | accession | assembly level | database | NCBI tax ID |
|---|---|---|---|---|---|
| 66792 | Heyndrickxia coagulans DSM 2314 | GCA_006716385 | complete | ncbi | 1398 |
| 66792 | Bacillus coagulans strain DSM 2314 | 1398.125 | complete | patric | 1398 |
GC content
- @ref: 1042
- GC-content: 45.3
Genome-based predictions
predictions
| trait | prediction | confidence | training_data |
|---|---|---|---|
| spore-forming | yes | 95 | no |
| flagellated | yes | 80.82 | no |
| gram-positive | yes | 83.36 | no |
| anaerobic | no | 98.436 | no |
| aerobic | yes | 72.679 | no |
| halophile | yes | 53.995 | no |
| spore-forming | yes | 94.227 | no |
| thermophile | no | 57.818 | no |
| glucose-util | yes | 92.351 | no |
| motile | yes | 88.967 | no |
| glucose-ferment | no | 69.451 | no |
External links
@ref: 1042
culture collection no.: DSM 2314, ATCC 23498, NCIB 10276, JCM 20478, IAM 12320, NCIMB 10276
straininfo link
- @ref: 70325
- straininfo: 92159
literature
| topic | Pubmed-ID | title | authors | journal | DOI | year | mesh | topic2 |
|---|---|---|---|---|---|---|---|---|
| Metabolism | 18247027 | Lactic acid production from lime-treated wheat straw by Bacillus coagulans: neutralization of acid by fed-batch addition of alkaline substrate. | Maas RH, Bakker RR, Jansen ML, Visser D, de Jong E, Eggink G, Weusthuis RA | Appl Microbiol Biotechnol | 10.1007/s00253-008-1361-1 | 2008 | Bacillus/enzymology/*metabolism, Biodegradation, Environmental, Biomass, Bioreactors, Calcium Compounds/*chemistry, Calcium Hydroxide/*chemistry, *Fermentation, Hydrogen-Ion Concentration, Hydrolysis, Industrial Microbiology, Lactic Acid/chemistry/*metabolism, Oxides/*chemistry, Triticum/chemistry/*metabolism, Waste Products/analysis | Biotechnology |
| Metabolism | 27464829 | Precultivation of Bacillus coagulans DSM2314 in the presence of furfural decreases inhibitory effects of lignocellulosic by-products during L(+)-lactic acid fermentation. | van der Pol E, Springer J, Vriesendorp B, Weusthuis R, Eggink G | Appl Microbiol Biotechnol | 10.1007/s00253-016-7725-z | 2016 | Adaptation, Physiological, Bacillus coagulans/*drug effects/*metabolism/physiology, Biosynthetic Pathways/genetics, Cell Wall/metabolism, Culture Media/chemistry, Drug Tolerance, Fermentation, Furaldehyde/*metabolism/toxicity, Gene Expression Profiling, Lactic Acid/*metabolism, Lignin/*metabolism | Cultivation |
| Biotechnology | 27872661 | Production of l(+)-lactic acid from acid pretreated sugarcane bagasse using Bacillus coagulans DSM2314 in a simultaneous saccharification and fermentation strategy. | van der Pol EC, Eggink G, Weusthuis RA | Biotechnol Biofuels | 10.1186/s13068-016-0646-3 | 2016 | ||
| Biotechnology | 34799761 | Revisiting the production of L( +)-lactic acid from vine shoots: bioconversion improvements by employing thermotolerant bacteria. | Garita-Cambronero J, Hijosa-Valsero M, Paniagua-Garcia AI, Diez-Antolinez R | Appl Microbiol Biotechnol | 10.1007/s00253-021-11693-1 | 2021 | *Bacillus coagulans, Fermentation, Hydrolysis, Lactic Acid, *Wine |
Reference
| @id | authors | catalogue | doi/url | title |
|---|---|---|---|---|
| 1042 | Curators of the DSMZ | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 2314) | https://www.dsmz.de/collection/catalogue/details/culture/DSM-2314 | |
| 20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M. | 10.1099/ijsem.0.004332 | List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ | |
| 66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | https://diaspora-project.de/progress.html#genomes | Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | |
| 67770 | Curators of the JCM | https://jcm.brc.riken.jp/en/ | ||
| 69480 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | https://diaspora-project.de/progress.html#genomes | Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | |
| 69481 | Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch | 10.21203/rs.3.rs-2527258/v1 | Predictions based on the model GenomeNet Sporulation v. 1 | |
| 70325 | Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J. | 10.60712/SI-ID92159.1 | StrainInfo: A central database for resolving microbial strain identifiers |