Strain identifier

BacDive ID: 6405

Type strain: No

Species: Lactobacillus acidophilus

Strain history: DSM 20242 <-- ATCC.

NCBI tax ID(s): 1226679 (strain), 1579 (species)

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General

@ref: 8653

BacDive-ID: 6405

DSM-Number: 20242

keywords: genome sequence, Bacteria, anaerobe, mesophilic, Gram-positive, lactate production, human pathogen

description: Lactobacillus acidophilus DSM 20242 is an anaerobe, mesophilic, Gram-positive human pathogen that produces lactate and was isolated from Vagina.

NCBI tax id

NCBI tax idMatching level
1226679strain
1579species

strain history

@refhistory
8653<- ATCC
67770DSM 20242 <-- ATCC.

doi: 10.13145/bacdive6405.20230509.8.1

Name and taxonomic classification

LPSN

  • @ref: 20215
  • description: domain/bacteria
  • keyword: phylum/bacillota
  • domain: Bacteria
  • phylum: Bacillota
  • class: Bacilli
  • order: Lactobacillales
  • family: Lactobacillaceae
  • genus: Lactobacillus
  • species: Lactobacillus acidophilus
  • full scientific name: Lactobacillus acidophilus (Moro 1900) Hansen and Mocquot 1970 (Approved Lists 1980)

  • synonyms

    • @ref: 20215
    • synonym: Bacillus acidophilus

@ref: 8653

domain: Bacteria

phylum: Firmicutes

class: Bacilli

order: Lactobacillales

family: Lactobacillaceae

genus: Lactobacillus

species: Lactobacillus acidophilus

full scientific name: Lactobacillus acidophilus (Moro 1900) Hansen and Mocquot 1970

type strain: no

Morphology

cell morphology

  • @ref: 69480
  • gram stain: positive
  • confidence: 100

Culture and growth conditions

culture medium

@refnamegrowthlinkcomposition
8653MRS MEDIUM (DSMZ Medium 11)yeshttps://mediadive.dsmz.de/medium/11Name: MRS MEDIUM (DSMZ Medium 11) Composition: Glucose 20.0 g/l Casein peptone 10.0 g/l Meat extract 10.0 g/l Na-acetate 5.0 g/l Yeast extract 5.0 g/l (NH4)3 citrate 2.0 g/l K2HPO4 2.0 g/l Tween 80 1.0 g/l MgSO4 x 7 H2O 0.2 g/l MnSO4 x H2O 0.05 g/l Distilled water
35006MEDIUM 40- for Lactobacillus and LeuconostocyesDistilled water make up to (1000.000 ml);Man Rogosa Sharp agar (68.000 g)

culture temp

@refgrowthtypetemperaturerange
8653positivegrowth37mesophilic
35006positivegrowth37mesophilic
67770positivegrowth37mesophilic

Physiology and metabolism

oxygen tolerance

@refoxygen tolerance
8653anaerobe
8653microaerophile

spore formation

@refspore formationconfidence
69481no100
69480no99.999

compound production

  • @ref: 8653
  • compound: DL lactic acid

murein

  • @ref: 8653
  • murein short key: A11.31
  • type: A4alpha L-Lys-D-Asp

metabolite utilization

@refmetaboliteutilization activitykind of utilization testedChebi-ID
68371Potassium 5-ketogluconate-builds acid from
68371Potassium 2-ketogluconate-builds acid from
68371gluconate-builds acid from24265
68371L-arabitol-builds acid from18403
68371D-arabitol-builds acid from18333
68371L-fucose-builds acid from18287
68371D-fucose-builds acid from28847
68371D-tagatose-builds acid from16443
68371D-lyxose-builds acid from62318
68371turanose-builds acid from32528
68371xylitol-builds acid from17151
68371glycogen-builds acid from28087
68371starch-builds acid from28017
68371melezitose-builds acid from6731
68371inulin-builds acid from15443
68371trehalose+builds acid from27082
68371sucrose+builds acid from17992
68371melibiose-builds acid from28053
68371lactose+builds acid from17716
68371maltose+builds acid from17306
68371salicin+builds acid from17814
68371esculin+builds acid from4853
68371arbutin-builds acid from18305
68371N-acetylglucosamine+builds acid from59640
68371methyl alpha-D-glucopyranoside-builds acid from320061
68371methyl alpha-D-mannoside-builds acid from43943
68371D-sorbitol-builds acid from17924
68371D-mannitol-builds acid from16899
68371myo-inositol-builds acid from17268
68371galactitol-builds acid from16813
68371L-rhamnose-builds acid from62345
68371L-sorbose-builds acid from17266
68371D-mannose+builds acid from16024
68371D-fructose+builds acid from15824
68371D-glucose+builds acid from17634
68371D-galactose+builds acid from12936
68371methyl beta-D-xylopyranoside-builds acid from74863
68371ribitol-builds acid from15963
68371L-xylose-builds acid from65328
68371D-xylose-builds acid from65327
68371D-ribose-builds acid from16988
68371L-arabinose-builds acid from30849
68371D-arabinose-builds acid from17108
68371erythritol-builds acid from17113
68371glycerol-builds acid from17754

API 50CHac

@refQGLYERYDARALARARIBDXYLLXYLADOMDXGALGLUFRUMNESBERHADULINOMANSORMDMMDGNAGAMYARBESCSALCELMALLACMELSACTREINUMLZRAFAMDGLYGXLTGENTURLYXTAGDFUCLFUCDARLLARLGNT2KG5KG
8653----------++++--------+--++-++-++-----------------
8653----------++++--------++-+++++-++--+---+----------
8653----------++++--------++-++-++-++--+---+----------

Isolation, sampling and environmental information

isolation

  • @ref: 67770
  • sample type: Vagina

Safety information

risk assessment

  • @ref: 8653
  • pathogenicity human: yes, in single cases
  • biosafety level: 1
  • biosafety level comment: Risk group (German classification)

Sequence information

Genome sequences

@refdescriptionaccessionassembly leveldatabaseNCBI tax ID
66792Lactobacillus acidophilus DSM 202421226679.3wgspatric1226679
66792Lactobacillus acidophilus DSM 202422602041538draftimg1226679
67770Lactobacillus acidophilus DSM 20242GCA_000442825contigncbi1226679

GC content

@refGC-content
865336.7
6777035

Genome-based predictions

predictions

traitpredictionconfidencetraining_data
spore-formingno100no
motileno95.596no
gram-positiveyes94.491no
anaerobicyes65.124no
aerobicno97.521yes
halophileyes82.53no
spore-formingno95.821no
thermophileno99.545yes
glucose-utilyes94.402no
flagellatedno97.363no
glucose-fermentyes90.998no

External links

@ref: 8653

culture collection no.: DSM 20242, JCM 2124

straininfo link

  • @ref: 75878
  • straininfo: 265364

literature

topicPubmed-IDtitleauthorsjournalDOIyearmeshtopic2
Phylogeny9066117Isolation and partial characterization of bacteriocins produced by Lactobacillus gasseri JCM 2124.Tahara T, Yoshioka S, Utsumi R, Kanatani KFEMS Microbiol Lett10.1111/j.1574-6968.1997.tb10273.x1997Amino Acid Sequence, Bacteriocins/chemistry/genetics/*isolation & purification, Chromatography, Ion Exchange, Lactobacillus/*chemistry/metabolism, Mass Spectrometry, Molecular Sequence DataGenetics
Enzymology23231860Hypolipidemic effects of lactic acid bacteria fermented cereal in rats.Banjoko IO, Adeyanju MM, Ademuyiwa O, Adebawo OO, Olalere RA, Kolawole MO, Adegbola IA, Adesanmi TA, Oladunjoye TO, Ogunnowo AA, Shorinola AA, Daropale O, Babatope EB, Osibogun AO, Ogunfowokan DT, Jentegbe TA, Apelehin TG, Ogunnowo O, Olokodana O, Fetuga FY, Omitola M, Okafor LA, Ebohon CL, Ita JO, Disu KA, Ogherebe O, Eriobu SU, Bakare AALipids Health Dis10.1186/1476-511X-11-1702012Animals, Bifidobacterium/enzymology, Diet, High-Fat, *Dyslipidemias/blood/drug therapy, Edible Grain/*chemistry, *Fermentation, Food Analysis, *Hypolipidemic Agents/chemistry/pharmacology, Lactic Acid/biosynthesis, Lactobacillus acidophilus/enzymology, Lactobacillus helveticus/enzymology, *Lipids/analysis/blood/chemistry, Rats
Metabolism30919101The antioxidant and prebiotic properties of lactobionic acid.Goderska KAppl Microbiol Biotechnol10.1007/s00253-019-09754-72019Antioxidants/*chemistry/*metabolism, Disaccharides/*chemistry/*metabolism, Hot Temperature, Lactobacillus fermentum/growth & development/metabolism, Oxidation-Reduction, Peroxides/chemistry, Prebiotics/*analysis, Pseudomonas/*metabolism, Rapeseed Oil/chemistry, Whey/metabolism/*microbiology, Whey Proteins/metabolismStress

Reference

@idauthorscataloguedoi/urltitle
8653Curators of the DSMZLeibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 20242)https://www.dsmz.de/collection/catalogue/details/culture/DSM-20242
20215Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.10.1099/ijsem.0.004332List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ
35006Curators of the CIPhttps://brclims.pasteur.fr/brcWeb/souche/detail/1/9964
66792Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmannhttps://diaspora-project.de/progress.html#genomesAutomatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)
67770Curators of the JCMhttps://jcm.brc.riken.jp/en/
68371Automatically annotated from API 50CH acid
69480Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmannhttps://diaspora-project.de/progress.html#genomesPredictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)
69481Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch10.21203/rs.3.rs-2527258/v1Predictions based on the model GenomeNet Sporulation v. 1
75878Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.10.60712/SI-ID265364.1StrainInfo: A central database for resolving microbial strain identifiers