Strain identifier
BacDive ID: 6403
Type strain:
Species: Lactobacillus acidophilus
Strain Designation: A 16
Strain history: <- E. Lauer <- F. Gasser <- M.E. Sharpe, A16
NCBI tax ID(s): 1226676 (strain), 1579 (species)
General
@ref: 3477
BacDive-ID: 6403
DSM-Number: 9126
keywords: genome sequence, Bacteria, mesophilic, Gram-positive, human pathogen
description: Lactobacillus acidophilus A 16 is a mesophilic, Gram-positive human pathogen of the family Lactobacillaceae.
NCBI tax id
NCBI tax id | Matching level |
---|---|
1226676 | strain |
1579 | species |
strain history
- @ref: 3477
- history: <- E. Lauer <- F. Gasser <- M.E. Sharpe, A16
doi: 10.13145/bacdive6403.20230509.8.1
Name and taxonomic classification
LPSN
- @ref: 20215
- description: domain/bacteria
- keyword: phylum/bacillota
- domain: Bacteria
- phylum: Bacillota
- class: Bacilli
- order: Lactobacillales
- family: Lactobacillaceae
- genus: Lactobacillus
- species: Lactobacillus acidophilus
- full scientific name: Lactobacillus acidophilus (Moro 1900) Hansen and Mocquot 1970 (Approved Lists 1980)
synonyms
- @ref: 20215
- synonym: Bacillus acidophilus
@ref: 3477
domain: Bacteria
phylum: Firmicutes
class: Bacilli
order: Lactobacillales
family: Lactobacillaceae
genus: Lactobacillus
species: Lactobacillus acidophilus
full scientific name: Lactobacillus acidophilus (Moro 1900) Hansen and Mocquot 1970
strain designation: A 16
type strain: no
Morphology
cell morphology
- @ref: 69480
- gram stain: positive
- confidence: 100
Culture and growth conditions
culture medium
- @ref: 3477
- name: MRS MEDIUM (DSMZ Medium 11)
- growth: yes
- link: https://mediadive.dsmz.de/medium/11
- composition: Name: MRS MEDIUM (DSMZ Medium 11) Composition: Glucose 20.0 g/l Casein peptone 10.0 g/l Meat extract 10.0 g/l Na-acetate 5.0 g/l Yeast extract 5.0 g/l (NH4)3 citrate 2.0 g/l K2HPO4 2.0 g/l Tween 80 1.0 g/l MgSO4 x 7 H2O 0.2 g/l MnSO4 x H2O 0.05 g/l Distilled water
culture temp
- @ref: 3477
- growth: positive
- type: growth
- temperature: 37
- range: mesophilic
Physiology and metabolism
spore formation
@ref | spore formation | confidence |
---|---|---|
69481 | no | 100 |
69480 | no | 99.999 |
murein
- @ref: 3477
- murein short key: A11.31
- type: A4alpha L-Lys-D-Asp
metabolite utilization
@ref | metabolite | utilization activity | kind of utilization tested | Chebi-ID |
---|---|---|---|---|
68371 | Potassium 5-ketogluconate | - | builds acid from | |
68371 | Potassium 2-ketogluconate | - | builds acid from | |
68371 | gluconate | - | builds acid from | 24265 |
68371 | L-arabitol | - | builds acid from | 18403 |
68371 | D-arabitol | - | builds acid from | 18333 |
68371 | L-fucose | - | builds acid from | 18287 |
68371 | D-fucose | - | builds acid from | 28847 |
68371 | D-tagatose | - | builds acid from | 16443 |
68371 | D-lyxose | - | builds acid from | 62318 |
68371 | turanose | - | builds acid from | 32528 |
68371 | xylitol | - | builds acid from | 17151 |
68371 | glycogen | - | builds acid from | 28087 |
68371 | starch | - | builds acid from | 28017 |
68371 | melezitose | - | builds acid from | 6731 |
68371 | inulin | - | builds acid from | 15443 |
68371 | sucrose | + | builds acid from | 17992 |
68371 | melibiose | - | builds acid from | 28053 |
68371 | maltose | + | builds acid from | 17306 |
68371 | esculin | + | builds acid from | 4853 |
68371 | arbutin | - | builds acid from | 18305 |
68371 | methyl alpha-D-glucopyranoside | - | builds acid from | 320061 |
68371 | methyl alpha-D-mannoside | - | builds acid from | 43943 |
68371 | D-sorbitol | - | builds acid from | 17924 |
68371 | D-mannitol | - | builds acid from | 16899 |
68371 | myo-inositol | - | builds acid from | 17268 |
68371 | galactitol | - | builds acid from | 16813 |
68371 | L-rhamnose | - | builds acid from | 62345 |
68371 | L-sorbose | - | builds acid from | 17266 |
68371 | D-fructose | + | builds acid from | 15824 |
68371 | D-glucose | + | builds acid from | 17634 |
68371 | methyl beta-D-xylopyranoside | - | builds acid from | 74863 |
68371 | ribitol | - | builds acid from | 15963 |
68371 | L-xylose | - | builds acid from | 65328 |
68371 | D-xylose | - | builds acid from | 65327 |
68371 | D-ribose | - | builds acid from | 16988 |
68371 | L-arabinose | - | builds acid from | 30849 |
68371 | D-arabinose | - | builds acid from | 17108 |
68371 | erythritol | - | builds acid from | 17113 |
68371 | glycerol | - | builds acid from | 17754 |
API 50CHac
@ref | Q | GLY | ERY | DARA | LARA | RIB | DXYL | LXYL | ADO | MDX | GAL | GLU | FRU | MNE | SBE | RHA | DUL | INO | MAN | SOR | MDM | MDG | NAG | AMY | ARB | ESC | SAL | CEL | MAL | LAC | MEL | SAC | TRE | INU | MLZ | RAF | AMD | GLYG | XLT | GEN | TUR | LYX | TAG | DFUC | LFUC | DARL | LARL | GNT | 2KG | 5KG |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3477 | - | - | - | - | - | - | - | - | - | - | + | + | + | + | - | - | - | - | - | - | - | - | + | - | - | + | + | + | + | + | - | + | + | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
3477 | - | - | - | - | - | - | - | - | - | - | + | + | + | + | - | - | - | - | - | - | - | - | + | - | - | + | + | + | + | + | - | + | + | - | - | + | - | - | - | + | - | - | - | - | - | - | - | - | - | - |
3477 | - | - | - | - | - | - | - | - | - | - | - | + | + | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | + | - | - | + | + | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
3477 | - | - | - | - | - | - | - | - | - | - | - | + | + | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | + | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
3477 | - | - | - | - | - | - | - | - | - | - | + | + | + | + | - | - | - | - | - | - | - | - | + | +/- | - | + | + | + | + | + | - | + | + | - | - | + | - | - | - | + | - | - | - | - | - | - | - | - | - | - |
Safety information
risk assessment
- @ref: 3477
- pathogenicity human: yes, in single cases
- biosafety level: 1
- biosafety level comment: Risk group (German classification)
Sequence information
Genome sequences
@ref | description | accession | assembly level | database | NCBI tax ID |
---|---|---|---|---|---|
66792 | Lactobacillus acidophilus DSM 9126 | GCA_000469745 | scaffold | ncbi | 1226676 |
66792 | Lactobacillus acidophilus DSM 9126 | 1226676.3 | wgs | patric | 1226676 |
Genome-based predictions
predictions
trait | prediction | confidence | training_data |
---|---|---|---|
spore-forming | no | 100 | no |
motile | no | 95.679 | no |
flagellated | no | 97.235 | no |
gram-positive | yes | 94.305 | no |
anaerobic | yes | 64.773 | no |
aerobic | no | 97.442 | no |
halophile | yes | 82.702 | no |
spore-forming | no | 96.053 | no |
thermophile | no | 99.52 | yes |
glucose-util | yes | 94.607 | no |
glucose-ferment | yes | 90.69 | no |
External links
@ref: 3477
culture collection no.: DSM 9126, ATCC 13651, NCDO 1360
straininfo link
- @ref: 75876
- straininfo: 14521
literature
topic | Pubmed-ID | title | authors | journal | DOI | year | mesh | topic2 |
---|---|---|---|---|---|---|---|---|
Enzymology | 6419677 | Production and properties of alpha-glucosidase from Lactobacillus acidophilus. | Li KB, Chan KY | Appl Environ Microbiol | 10.1128/aem.46.6.1380-1387.1983 | 1983 | Carbohydrates/pharmacology, Cations, Cytoplasm/enzymology, Glucosidases/*biosynthesis, Hydrogen-Ion Concentration, Lactobacillus acidophilus/*enzymology, Temperature, Urea/pharmacology, alpha-Glucosidases/*biosynthesis/metabolism | Biotechnology |
Genetics | 23969059 | Draft Genome Sequences of Five Strains of Lactobacillus acidophilus, Strain CIP 76.13T, Isolated from Humans, Strains CIRM-BIA 442 and CIRM-BIA 445, Isolated from Dairy Products, and Strains DSM 20242 and DSM 9126 of Unknown Origin. | Falentin H, Cousin S, Clermont D, Creno S, Ma L, Chuat V, Loux V, Rudiger P, Bizet C, Bouchier C | Genome Announc | 10.1128/genomeA.00658-13 | 2013 | Phylogeny | |
Pathogenicity | 29224862 | In vitro investigation of anticancer, antihypertensive, antidiabetic, and antioxidant activities of camel milk fermented with camel milk probiotic: A comparative study with fermented bovine milk. | Ayyash M, Al-Dhaheri AS, Al Mahadin S, Kizhakkayil J, Abushelaibi A | J Dairy Sci | 10.3168/jds.2017-13400 | 2017 | Animals, Antihypertensive Agents/*pharmacology, Antineoplastic Agents/*pharmacology, Antioxidants/*metabolism, Caco-2 Cells, Camelus, Cattle, Cell Proliferation/drug effects, Enzyme Activation/drug effects, Fermentation, HeLa Cells, Humans, Hypoglycemic Agents/*pharmacology, Lactobacillus acidophilus/chemistry, Lactococcus lactis/*chemistry, MCF-7 Cells, Milk/*chemistry/microbiology, Probiotics/administration & dosage/pharmacology | Metabolism |
Reference
@id | authors | catalogue | doi/url | title |
---|---|---|---|---|
3477 | Curators of the DSMZ | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 9126) | https://www.dsmz.de/collection/catalogue/details/culture/DSM-9126 | |
20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M. | 10.1099/ijsem.0.004332 | List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ | |
66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | https://diaspora-project.de/progress.html#genomes | Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | |
68371 | Automatically annotated from API 50CH acid | |||
69480 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | https://diaspora-project.de/progress.html#genomes | Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | |
69481 | Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch | 10.21203/rs.3.rs-2527258/v1 | Predictions based on the model GenomeNet Sporulation v. 1 | |
75876 | Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J. | 10.60712/SI-ID14521.1 | StrainInfo: A central database for resolving microbial strain identifiers |