Strain identifier
BacDive ID: 4986
Type strain:
Species: Morganella morganii
Strain Designation: M 11, 33 M
Strain history: CIP <- 1953, H. de R. Morgan: strain 33 M, Proteus morganii
NCBI tax ID(s): 1223504 (strain), 582 (species)
General
@ref: 9174
BacDive-ID: 4986
DSM-Number: 30164
keywords: genome sequence, 16S sequence, Bacteria, facultative anaerobe, mesophilic, Gram-negative, rod-shaped, antibiotic resistance, human pathogen
description: Morganella morganii M 11 is a facultative anaerobe, mesophilic, Gram-negative human pathogen that has multiple antibiotic resistances and was isolated from stool of a summer diarrhoea case.
NCBI tax id
NCBI tax id | Matching level |
---|---|
582 | species |
1223504 | strain |
strain history
@ref | history |
---|---|
9174 | <- ATCC; ATCC 25830 <- M. J. Pelczar; M 11 (Proteus morganii) <- NCTC; NCTC 235 <- H. de R. Morgan; 33 M |
40631 | 1953, H. de R. Morgan: strain 33 M, Proteus morganii |
67770 | R. Sakazaki <-- ATCC 25830 <-- M. J. Pelczar M11 <-- NCTC 235 <-- H. de R. Morgan. |
121143 | CIP <- 1953, H. de R. Morgan: strain 33 M, Proteus morganii |
doi: 10.13145/bacdive4986.20230509.8.1
Name and taxonomic classification
LPSN
- @ref: 20215
- description: domain/bacteria
- keyword: phylum/pseudomonadota
- domain: Bacteria
- phylum: Pseudomonadota
- class: Gammaproteobacteria
- order: Enterobacterales
- family: Morganellaceae
- genus: Morganella
- species: Morganella morganii
- full scientific name: Morganella morganii (Winslow et al. 1919) Fulton 1943 (Approved Lists 1980)
synonyms
@ref synonym 20215 Proteus morganii 20215 Bacillus morgani
@ref: 9174
domain: Bacteria
phylum: Proteobacteria
class: Gammaproteobacteria
order: Enterobacteriales, not validated
family: Morganellaceae
genus: Morganella
species: Morganella morganii subsp. morganii
full scientific name: Morganella morganii subsp. morganii (Winslow et al. 1919) Jensen et al. 1992
strain designation: M 11, 33 M
type strain: yes
Morphology
cell morphology
- @ref: 121143
- gram stain: negative
- cell shape: rod-shaped
Culture and growth conditions
culture medium
@ref | name | growth | link | composition |
---|---|---|---|---|
9174 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | yes | https://mediadive.dsmz.de/medium/693 | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base |
9174 | TRYPTICASE SOY BROTH AGAR (DSMZ Medium 535) | yes | https://mediadive.dsmz.de/medium/535 | Name: TRYPTICASE SOY BROTH AGAR (DSMZ Medium 535) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Distilled water |
40631 | MEDIUM 3 - Columbia agar | yes | Columbia agar (39.000 g);distilled water (1000.000 ml) | |
121143 | CIP Medium 72 | yes | https://catalogue-crbip.pasteur.fr/fiche_milieu.xhtml?crbip=72 | |
121143 | CIP Medium 3 | yes | https://catalogue-crbip.pasteur.fr/fiche_milieu.xhtml?crbip=3 |
culture temp
@ref | growth | type | temperature | range |
---|---|---|---|---|
9174 | positive | growth | 37 | mesophilic |
40631 | positive | growth | 30 | mesophilic |
67770 | positive | growth | 37 | mesophilic |
121143 | positive | growth | 10-41 | |
121143 | no | growth | 5 | psychrophilic |
121143 | no | growth | 44 | thermophilic |
Physiology and metabolism
oxygen tolerance
- @ref: 121143
- oxygen tolerance: facultative anaerobe
antibiogram
- @ref: 9174
- medium: Mueller-Hinton Agar
- Penicillin G: 20
- oxacillin: 10
- ampicillin: 30
- ticarcillin: 40
- mezlocillin: 40
- cefalotin: 10
- cefazolin: 10
- cefotaxime: 50
- aztreonam: 50
- imipenem: 28-30
- tetracycline: 32
- chloramphenicol: 32
- gentamycin: 24-26
- amikacin: 26
- vancomycin: 0
- erythromycin: 0
- lincomycin: 8-10
- ofloxacin: 36-38
- norfloxacin: 38-40
- colistin: 0
- pipemidic acid: 30
- nitrofurantoin: 14-16
- bacitracin: 0
- polymyxin b: 0
- kanamycin: 38
- neomycin: 22
- doxycycline: 30
- ceftriaxone: 48
- clindamycin: 10-12
- fosfomycin: 20
- moxifloxacin: 32
- linezolid: 14
- nystatin: 0
- quinupristin/dalfopristin: 0
- teicoplanin: 0
- piperacillin/tazobactam: 42
compound production
- @ref: 9174
- compound: histidine decarboxylase
metabolite utilization
@ref | Chebi-ID | metabolite | utilization activity | kind of utilization tested |
---|---|---|---|---|
68368 | 30849 | L-arabinose | - | fermentation |
68368 | 27613 | amygdalin | - | fermentation |
68368 | 28053 | melibiose | - | fermentation |
68368 | 17992 | sucrose | - | fermentation |
68368 | 62345 | L-rhamnose | - | fermentation |
68368 | 17268 | myo-inositol | - | fermentation |
68368 | 16899 | D-mannitol | - | fermentation |
68368 | 17634 | D-glucose | + | fermentation |
68368 | 5291 | gelatin | - | hydrolysis |
68368 | 27897 | tryptophan | + | energy source |
68368 | 16199 | urea | + | hydrolysis |
68368 | 18257 | ornithine | + | degradation |
68368 | 25094 | lysine | - | degradation |
68368 | 29016 | arginine | - | hydrolysis |
121143 | 29864 | mannitol | + | fermentation |
121143 | 16947 | citrate | - | carbon source |
121143 | 17234 | glucose | + | fermentation |
121143 | 17716 | lactose | - | fermentation |
121143 | 17632 | nitrate | + | reduction |
121143 | 16301 | nitrite | - | reduction |
121143 | 15792 | malonate | - | assimilation |
121143 | 132112 | sodium thiosulfate | - | builds gas from |
121143 | 17234 | glucose | + | degradation |
antibiotic resistance
- @ref: 121143
- metabolite: 0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate)
- is antibiotic: yes
- is sensitive: no
- is resistant: yes
metabolite production
@ref | Chebi-ID | metabolite | production |
---|---|---|---|
68368 | 35581 | indole | yes |
68368 | 16136 | hydrogen sulfide | no |
121143 | 35581 | indole | yes |
metabolite tests
- @ref: 68368
- Chebi-ID: 35581
- metabolite: indole
- indole test: +
enzymes
@ref | value | activity | ec |
---|---|---|---|
68382 | alpha-fucosidase | - | 3.2.1.51 |
68382 | alpha-mannosidase | - | 3.2.1.24 |
68382 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 |
68382 | beta-glucosidase | - | 3.2.1.21 |
68382 | alpha-glucosidase | - | 3.2.1.20 |
68382 | beta-glucuronidase | - | 3.2.1.31 |
68382 | beta-galactosidase | - | 3.2.1.23 |
68382 | alpha-galactosidase | - | 3.2.1.22 |
68382 | naphthol-AS-BI-phosphohydrolase | - | |
68382 | acid phosphatase | - | 3.1.3.2 |
68382 | alpha-chymotrypsin | - | 3.4.21.1 |
68382 | trypsin | - | 3.4.21.4 |
68382 | cystine arylamidase | - | 3.4.11.3 |
68382 | valine arylamidase | - | |
68382 | leucine arylamidase | - | 3.4.11.1 |
68382 | lipase (C 14) | - | |
68382 | esterase lipase (C 8) | - | |
68382 | esterase (C 4) | - | |
68382 | alkaline phosphatase | - | 3.1.3.1 |
68368 | cytochrome oxidase | - | 1.9.3.1 |
68368 | gelatinase | - | |
68368 | tryptophan deaminase | + | 4.1.99.1 |
68368 | urease | + | 3.5.1.5 |
68368 | ornithine decarboxylase | + | 4.1.1.17 |
68368 | lysine decarboxylase | - | 4.1.1.18 |
68368 | arginine dihydrolase | - | 3.5.3.6 |
68368 | beta-galactosidase | - | 3.2.1.23 |
121143 | oxidase | - | |
121143 | alcohol dehydrogenase | - | 1.1.1.1 |
121143 | catalase | + | 1.11.1.6 |
121143 | lysine decarboxylase | - | 4.1.1.18 |
121143 | ornithine decarboxylase | + | 4.1.1.17 |
121143 | phenylalanine ammonia-lyase | + | 4.3.1.24 |
121143 | tryptophan deaminase | + | |
121143 | urease | + | 3.5.1.5 |
API zym
@ref | Control | Alkaline phosphatase | Esterase | Esterase Lipase | Lipase | Leucine arylamidase | Valine arylamidase | Cystine arylamidase | Trypsin | alpha- Chymotrypsin | Acid phosphatase | Naphthol-AS-BI-phosphohydrolase | alpha- Galactosidase | beta- Galactosidase | beta- Glucuronidase | alpha- Glucosidase | beta- Glucosidase | N-acetyl-beta- glucosaminidase | alpha- Mannosidase | alpha- Fucosidase |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
121143 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
API 20E
@ref | ONPG | ADH Arg | LDC Lys | ODC | CIT | H2S | URE | TDA Trp | IND | VP | GEL | GLU | MAN | INO | Sor | RHA | SAC | MEL | AMY | ARA | OX |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
9174 | - | - | - | + | + | - | + | + | + | - | - | + | - | - | - | - | - | - | - | - | - |
9174 | - | - | - | + | +/- | - | + | + | + | + | - | + | - | - | + | - | - | - | - | - | - |
9174 | - | - | - | + | - | - | + | + | + | + | - | + | - | - | + | - | - | - | - | - | - |
9174 | - | - | - | + | - | - | + | + | + | + | - | + | - | - | + | - | - | - | - | - | - |
Isolation, sampling and environmental information
isolation
@ref | sample type | geographic location | country | origin.country | continent | isolation date |
---|---|---|---|---|---|---|
9174 | stool of a summer diarrhoea case | |||||
44889 | Human feces,summer diarrhoea | |||||
67770 | Patient with summer diarrhoea | |||||
121143 | A case of summer diarrhoea | London | United Kingdom | GBR | Europe | 1920 |
isolation source categories
- Cat1: #Host Body Product
- Cat2: #Gastrointestinal tract
- Cat3: #Feces (Stool)
taxonmaps
- @ref: 69479
- File name: preview.99_237.png
- url: https://microbeatlas.org/index.html?action=taxon&taxon_id=90_6;96_168;97_181;98_202;99_237&stattab=map
- Last taxonomy: Morganella morganii subclade
- 16S sequence: HM122047
- Sequence Identity:
- Total samples: 34343
- soil counts: 3066
- aquatic counts: 3670
- animal counts: 26248
- plant counts: 1359
Safety information
risk assessment
@ref | pathogenicity human | pathogenicity animal | biosafety level | biosafety level comment |
---|---|---|---|---|
9174 | yes | yes | 2 | Risk group (German classification) |
121143 | 2 | Risk group (French classification) |
Sequence information
16S sequences
@ref | description | accession | length | database | NCBI tax ID |
---|---|---|---|---|---|
20218 | Morganella morganii subsp. morganii strain ATCC25830 16S ribosomal RNA gene, partial sequence | AF500485 | 786 | ena | 180434 |
20218 | Morganella morganii 16S rRNA gene, strain CIPA231T | AJ301681 | 1502 | ena | 180434 |
20218 | Morganella morganii subsp. morganii strain ATCC 25830 16S ribosomal RNA gene, partial sequence | HM122047 | 1471 | ena | 180434 |
20218 | Morganella morganii strain ATCC 8076 16S ribosomal RNA gene, partial sequence | FJ971868 | 797 | ena | 582 |
20218 | Morganella morganii gene for 16S rRNA, partial sequence, strain:JCM1672 | AB089243 | 1436 | ena | 582 |
20218 | Morganella morganii strain LMG 7874 16S ribosomal RNA gene, partial sequence | DQ358131 | 1356 | ena | 582 |
20218 | Morganella morganii subsp. morganii gene for 16S rRNA, partial sequence, strain: NBRC 3848 | AB680150 | 1468 | ena | 1223504 |
20218 | Morganella morganii strain NCTC 00235 16S ribosomal RNA gene, partial sequence | DQ885260 | 1403 | ena | 582 |
Genome sequences
@ref | description | accession | assembly level | database | NCBI tax ID |
---|---|---|---|---|---|
66792 | Morganella morganii DSM 30164 | GCA_019243775 | complete | ncbi | 582 |
66792 | Morganella morganii subsp. morganii ATCC 25830 | GCA_006094455 | complete | ncbi | 180434 |
66792 | Morganella morganii NCTC235 | GCA_900635025 | complete | ncbi | 582 |
66792 | Morganella morganii strain DSM 30164 | 582.587 | complete | patric | 582 |
66792 | Morganella morganii strain NCTC235 | 582.221 | complete | patric | 582 |
66792 | Morganella morganii subsp. morganii NBRC 3848 | 1223504.3 | wgs | patric | 1223504 |
66792 | Morganella morganii subsp. morganii strain ATCC 25830 | 180434.13 | complete | patric | 180434 |
66792 | Morganella morganii morganii NBRC 3848 | 2675903361 | draft | img | 1223504 |
67770 | Morganella morganii subsp. morganii NBRC 3848 | GCA_001598895 | contig | ncbi | 1223504 |
Genome-based predictions
predictions
trait | prediction | confidence | training_data |
---|---|---|---|
flagellated | yes | 61.626 | no |
gram-positive | no | 98.19 | no |
anaerobic | no | 94.189 | no |
aerobic | yes | 82.735 | no |
halophile | no | 89.827 | no |
spore-forming | no | 96.764 | no |
motile | yes | 86.295 | no |
thermophile | no | 99.423 | yes |
glucose-util | yes | 88.547 | no |
glucose-ferment | yes | 87.115 | no |
External links
@ref: 9174
culture collection no.: DSM 30164, ATCC 25830, IFO 3848, LMG 7874, NBRC 3848, NCIB 235, NCTC 235, WDCM 00112, CCUG 6328, JCM 1672, ATCC 8076H, BCRC 10706, CECT 173, CGMCC 1.6767, CIP 103763, CIP A231, KACC 13822, NBRC 105691, NCCB 73065, NCIMB 235
straininfo link
- @ref: 74481
- straininfo: 36194
literature
topic | Pubmed-ID | title | authors | journal | DOI | year | mesh | topic2 |
---|---|---|---|---|---|---|---|---|
Enzymology | 96731 | Beta-lactamases: determination of their isoelectric points. | Barthelemy M, Guionie M, Labia R | Antimicrob Agents Chemother | 10.1128/AAC.13.4.695 | 1978 | Amidohydrolases/*analysis, Cephalosporinase/*analysis, Escherichia coli/enzymology, Isoelectric Focusing/methods, Isoelectric Point, Molecular Weight, Pseudomonas aeruginosa/enzymology | |
Phylogeny | 1390112 | Recognition of Morganella subspecies, with proposal of Morganella morganii subsp. morganii subsp. nov. and Morganella morganii subsp. sibonii subsp. nov. | Jensen KT, Frederiksen W, Hickman-Brenner FW, Steigerwalt AG, Riddle CF, Brenner DJ | Int J Syst Bacteriol | 10.1099/00207713-42-4-613 | 1992 | Bacterial Typing Techniques, Carboxy-Lyases/metabolism, DNA, Bacterial/chemistry, Enterobacteriaceae/*classification/genetics/metabolism, Fermentation, Humans, Nucleic Acid Hybridization, Ornithine Decarboxylase/metabolism, Phenotype, Trehalose/metabolism | Metabolism |
Pathogenicity | 1864765 | Mode of antibacterial action of cefprozil, a new cephalosporin, on Escherichia coli, Serratia marcescens and Morganella morganii. | Nishimoto K, Usui T, Miyake Y, Suginaka H | Hiroshima J Med Sci | 1991 | Bacteria/*drug effects/metabolism, Cephalosporins/metabolism/*pharmacology, Escherichia coli/drug effects, Peptidoglycan/biosynthesis, Proteus/drug effects, Serratia marcescens/drug effects, beta-Lactamases/metabolism | Metabolism | |
Phylogeny | 15033270 | Photobacterium phosphoreum caused a histamine fish poisoning incident. | Kanki M, Yoda T, Ishibashi M, Tsukamoto T | Int J Food Microbiol | 10.1016/j.ijfoodmicro.2003.08.019 | 2004 | Animals, DNA, Bacterial/analysis, DNA, Ribosomal/analysis, Fishes/*microbiology, Food Contamination, Food Handling/methods, Food Microbiology, Foodborne Diseases/*epidemiology, Histamine/*biosynthesis/isolation & purification, Japan/epidemiology, Photobacterium/*isolation & purification/*metabolism, Polymerase Chain Reaction, RNA, Ribosomal, 16S/genetics | Biotechnology |
Phylogeny | 17012582 | Morganella psychrotolerans sp. nov., a histamine-producing bacterium isolated from various seafoods. | Emborg J, Dalgaard P, Ahrens P | Int J Syst Evol Microbiol | 10.1099/ijs.0.64357-0 | 2006 | Animals, Bacterial Proteins/genetics, Cold Temperature, Fishes/*microbiology, Galactose/metabolism, Genes, rRNA, Histamine/*biosynthesis, Humans, Molecular Sequence Data, Morganella/*classification/genetics/growth & development/isolation & purification, Nucleic Acid Hybridization, Phylogeny, RNA, Ribosomal, 16S, Seafood/*microbiology, Sequence Analysis, DNA, Sodium Chloride/metabolism, Tuna/*microbiology | Metabolism |
Metabolism | 22200744 | [Inhibitory effect of essential oils, food additives, peracetic acid and detergents on bacterial histidine decarboxylase]. | Kamii E, Terada G, Akiyama J, Isshiki K | Shokuhin Eiseigaku Zasshi | 10.3358/shokueishi.52.271 | 2011 | Detergents/*pharmacology, Food Additives/*pharmacology, Foodborne Diseases/prevention & control, Histamine/metabolism/poisoning, Histidine/metabolism, Histidine Decarboxylase/*antagonists & inhibitors, Morganella morganii/*enzymology/metabolism, Oils, Volatile/*pharmacology, Peracetic Acid/*pharmacology, Sodium Hypochlorite/*pharmacology | Enzymology |
Metabolism | 22200745 | [Antibacterial activity of essential oil vapor for histamine-producing bacteria]. | Kamii E, Terada G, Akiyama J, Isshiki K | Shokuhin Eiseigaku Zasshi | 10.3358/shokueishi.52.276 | 2011 | Aldehydes/*pharmacology, Drug Resistance, Bacterial, Enterobacteriaceae/*drug effects/metabolism, Fish Products/microbiology, *Food Microbiology, Histamine/*metabolism, Isothiocyanates/*pharmacology, Morganella morganii/*drug effects/metabolism, Oils, Volatile/*pharmacology, Volatilization | Pathogenicity |
Pathogenicity | 22200801 | [Antibacterial effect of food additives and detergents against histamine-producing bacteria on food contact material surfaces]. | Kamii E, Terada G, Akiyama J, Isshiki K | Shokuhin Eiseigaku Zasshi | 10.3358/shokueishi.52.340 | 2011 | Detergents/*pharmacology, Dose-Response Relationship, Drug, Drug Resistance, Bacterial, Enterobacter aerogenes/*drug effects/metabolism, Enterobacteriaceae/*drug effects/metabolism, Food Additives/*pharmacology, Food Contamination/prevention & control, Food Handling/*instrumentation, Foodborne Diseases/microbiology/prevention & control, Histamine/biosynthesis/poisoning, Morganella morganii/*drug effects/metabolism, Sodium Hypochlorite/pharmacology | Metabolism |
Enzymology | 35822812 | The Identification of Ethidium Bromide-Degrading Bacteria from Laboratory Gel Electrophoresis Waste. | Gandhi VP, Kesari KK, Kumar A | BioTech (Basel) | 10.3390/biotech11010004 | 2022 |
Reference
@id | authors | catalogue | doi/url | title | journal | pubmed |
---|---|---|---|---|---|---|
9174 | Curators of the DSMZ | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 30164) | https://www.dsmz.de/collection/catalogue/details/culture/DSM-30164 | |||
20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M. | 10.1099/ijsem.0.004332 | List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ | |||
20218 | Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P. | 10.1016/j.syapm.2013.11.002 | StrainInfo introduces electronic passports for microorganisms. | Syst Appl Microbiol. 37: 42-50 2014 | 24321274 | |
40631 | Curators of the CIP | https://brclims.pasteur.fr/brcWeb/souche/detail/1/10945 | ||||
44889 | Curators of the CCUG | Culture Collection University of Gothenburg (CCUG) (CCUG 6328) | https://www.ccug.se/strain?id=6328 | |||
66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | https://diaspora-project.de/progress.html#genomes | Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | |||
67770 | Curators of the JCM | https://jcm.brc.riken.jp/en/ | ||||
68368 | Automatically annotated from API 20E | |||||
68382 | Automatically annotated from API zym | |||||
69479 | João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich. | https://microbeatlas.org/ | MicrobeAtlas 1.0 beta | |||
74481 | Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J. | 10.60712/SI-ID36194.1 | StrainInfo: A central database for resolving microbial strain identifiers | |||
121143 | Curators of the CIP | Collection of Institut Pasteur (CIP A231) | https://catalogue-crbip.pasteur.fr/fiche_catalogue.xhtml?crbip=CIP%20A231 |