Strain identifier

BacDive ID: 4962

Type strain: No

Species: Klebsiella pneumoniae

Strain Designation: K6, MCV37

Strain history: CIP <- 2014, NCTC <- 2007, H. Dalton, Hospital, Richmond, Virginia, USA: strain K6, MCV37

NCBI tax ID(s): 573 (species)

For citation purpose refer to the digital object identifier (doi) of the current version.
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General

@ref: 18197

BacDive-ID: 4962

DSM-Number: 26371

keywords: genome sequence, Bacteria, mesophilic, Gram-negative, antibiotic resistance, human pathogen

description: Klebsiella pneumoniae K6 is a mesophilic, Gram-negative human pathogen that has multiple antibiotic resistances and was isolated from urine of hospitalized patient.

NCBI tax id

  • NCBI tax id: 573
  • Matching level: species

strain history

@refhistory
18197<- LMG <- ATCC <- J. Swanson <- M. J. Ferraro <- G. Jacoby <- H. Dalton
122107CIP <- 2014, NCTC <- 2007, H. Dalton, Hospital, Richmond, Virginia, USA: strain K6, MCV37

doi: 10.13145/bacdive4962.20230509.8.1

Name and taxonomic classification

LPSN

  • @ref: 20215
  • description: domain/bacteria
  • keyword: phylum/pseudomonadota
  • domain: Bacteria
  • phylum: Pseudomonadota
  • class: Gammaproteobacteria
  • order: Enterobacterales
  • family: Enterobacteriaceae
  • genus: Klebsiella
  • species: Klebsiella pneumoniae
  • full scientific name: Klebsiella pneumoniae (Schroeter 1886) Trevisan 1887 (Approved Lists 1980)
  • synonyms

    • @ref: 20215
    • synonym: Hyalococcus pneumoniae

@ref: 18197

domain: Bacteria

phylum: Proteobacteria

class: Gammaproteobacteria

order: Enterobacteriales, not validated

family: Enterobacteriaceae

genus: Klebsiella

species: Klebsiella pneumoniae

full scientific name: Klebsiella pneumoniae (Schroeter 1886) Trevisan 1887

strain designation: K6, MCV37

type strain: no

Morphology

cell morphology

@refgram stainconfidencecell shapemotility
69480negative99.936
122107negativerod-shapedno

multimedia

  • @ref: 18197
  • multimedia content: https://www.dsmz.de/microorganisms/photos/DSM_26371.jpg
  • intellectual property rights: © Leibniz-Institut DSMZ

Culture and growth conditions

culture medium

@refnamegrowthlinkcomposition
18197COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)yeshttps://mediadive.dsmz.de/medium/693Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base
41591MEDIUM 72- for trypto casein soja agaryesDistilled water make up to (1000.000 ml);Trypto casein soy agar (40.000 g)
18197TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92)yeshttps://mediadive.dsmz.de/medium/92Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water
122107CIP Medium 72yeshttps://catalogue-crbip.pasteur.fr/fiche_milieu.xhtml?crbip=72

culture temp

@refgrowthtypetemperaturerange
18197positivegrowth30mesophilic
41591positivegrowth30mesophilic

Physiology and metabolism

antibiogram

@refmediumincubation temperatureincubation timeoxygen conditionPenicillin Goxacillinampicillinticarcillinmezlocillincefalotincefazolincefotaximeaztreonamimipenemtetracyclinechloramphenicolgentamycinamikacinvancomycinerythromycinlincomycinofloxacinnorfloxacincolistinpipemidic acidnitrofurantoinbacitracinpolymyxin bkanamycinneomycindoxycyclineceftriaxoneclindamycinfosfomycinmoxifloxacinlinezolidnystatinquinupristin/dalfopristinteicoplaninpiperacillin/tazobactam
18197Mueller-Hinton Agar301aerob000000020034-362026102606020221816120200101016014-1618000018
18197Mueller-Hinton Agar301aerob0000808-102010-12341210-121422-2406018-2028141212014-1614-1614102001618-20000018
18197Mueller-Hinton Agar301aerob000080102210-123614814-162600020-222216141401614-1616102001620000018
18197Mueller-Hinton Agar30aerob0000806221038148-101228080202414-161410-12016-1820208-102001820000020
18197Mueller-Hinton Agar301aerob00001008221040146-82024060222216141401620-22201020-2202020000020
18197Mueller-Hinton Agar30aerob000080622103412101626-28080222414-16161201614-16181020-22014-1620-22000020
18197Mueller-Hinton Agar30aerob000080620103614610240001820161012016221282001816000016-18

spore formation

@refspore formationconfidence
69481no100
69480no99.891
122107no

compound production

@refcompound
18197SHV-18 beta lactamase
18197extended spectrum ß-lactamase ESBL

metabolite utilization

@refChebi-IDmetaboliteutilization activitykind of utilization tested
6836830849L-arabinose+fermentation
6836827613amygdalin+fermentation
6836828053melibiose+fermentation
6836817992sucrose+fermentation
6836862345L-rhamnose+fermentation
6836830911sorbitol+fermentation
6836817268myo-inositol+fermentation
6836816899D-mannitol+fermentation
6836817634D-glucose+fermentation
683685291gelatin-hydrolysis
6836827897tryptophan-energy source
6836816947citrate+assimilation
6836818257ornithine-degradation
6836829016arginine-hydrolysis
6837418257ornithine-degradation
6837429016arginine-hydrolysis
6837425094lysine+degradation
6837416199urea+hydrolysis
6837418403L-arabitol-builds acid from
6837418024D-galacturonic acid+builds acid from
68374Potassium 5-ketogluconate-builds acid from
6837416899D-mannitol+builds acid from
6837417306maltose+builds acid from
6837415963ribitol+builds acid from
6837418394palatinose+builds acid from
6837415792malonate+assimilation
6837427897tryptophan-energy source
6837417634D-glucose+builds acid from
6837417992sucrose+builds acid from
6837430849L-arabinose+builds acid from
6837418333D-arabitol+builds acid from
6837427082trehalose+builds acid from
6837462345L-rhamnose+builds acid from
6837417268myo-inositol+builds acid from
6837417057cellobiose+builds acid from
6837430911sorbitol+builds acid from

metabolite production

@refChebi-IDmetaboliteproduction
6837435581indoleno
6836815688acetoinyes
6836835581indoleno
6836816136hydrogen sulfideno

metabolite tests

@refChebi-IDmetaboliteindole testvoges-proskauer-test
6837435581indole-
6836815688acetoin+
6836835581indole-

enzymes

@refvalueactivityec
68374L-aspartate arylamidase-3.4.11.21
68374alpha-maltosidase-
68374alpha-galactosidase+3.2.1.22
68374alpha-glucosidase-3.2.1.20
68374beta-galactosidase+3.2.1.23
68374N-acetyl-beta-glucosaminidase-3.2.1.52
68374beta-glucuronidase-3.2.1.31
68374beta-glucosidase+3.2.1.21
68374lipase-
68374urease+3.5.1.5
68374lysine decarboxylase+4.1.1.18
68374arginine dihydrolase-3.5.3.6
68374ornithine decarboxylase-4.1.1.17
68368gelatinase-
68368tryptophan deaminase-4.1.99.1
68368ornithine decarboxylase-4.1.1.17
68368arginine dihydrolase-3.5.3.6
68368beta-galactosidase+3.2.1.23

fatty acid profile

  • fatty acids

    @reffatty acidpercentageECL
    56773C12:00.612
    56773C14:01114
    56773C15:02.715
    56773C16:02116
    56773C17:00.917
    56773C13:0 3OH/C15:1 i I/H0.914.469
    56773C14:0 2OH6.215.205
    56773C14:0 3OH/C16:1 ISO I1815.485
    56773C16:1 ω7c1015.819
    56773C17:0 CYCLO12.316.888
    56773C18:1 ω7c /12t/9t15.417.824
    56773C19:0 CYCLO ω8c1.118.9
  • type of FA analysis: whole cell analysis
  • method/protocol: CCUG

API 20E

@refONPGADH ArgLDC LysODCCITH2SURETDA TrpINDVPGELGLUMANINOSorRHASACMELAMYARAOX
18197+-+/--+-+--+-+++++++++-
18197+-+-+-+--+-+++++++++-
56773+-+-+-+--+-+++++++++-
18197+-+-+-+--+-++++++++++
18197+-+-+----+-+++++++++-

API ID32E

@refODCADH ArgLDC LysURELARLGAT5KGLIPRPbeta GLUMANMALADOPLEbeta GURMNTINDbeta NAGbeta GALGLUSACLARADARLalpha GLUalpha GALTRERHAINOCELSORalphaMALAspA
56773--++-+---+++++-+--+++++-++++++--

Isolation, sampling and environmental information

isolation

@refsample typegeographic locationcountryorigin.countrycontinentisolation date
18197urine of hospitalized patientVirginia, RichmondUSAUSANorth America
56773Human urineVA,RichmondUSAUSANorth America
122107Human, UrineRichmond, VirginiaUnited States of AmericaUSANorth America1994

isolation source categories

Cat1Cat2Cat3
#Infection#Medical environment#Clinic
#Infection#Patient
#Host Body Product#Fluids#Urine

Safety information

risk assessment

@refpathogenicity humanpathogenicity animalbiosafety levelbiosafety level comment
18197yesyes2Risk group (German classification)
1221072Risk group (French classification)

Sequence information

Genome sequences

@refdescriptionaccessionassembly leveldatabaseNCBI tax ID
66792Klebsiella quasipneumoniae ATCC 700603GCA_001596075completencbi1463165
66792Klebsiella quasipneumoniae subsp. similipneumoniae ATCC 700603GCA_003181175completencbi1463164
66792Klebsiella pneumoniae k6GCA_016651535scaffoldncbi573
66792Klebsiella quasipneumoniae strain ATCC 7006031463165.70completepatric1463165
66792Klebsiella quasipneumoniae strain ATCC 7006031463165.4completepatric1463165
66792Klebsiella quasipneumoniae strain ATCC 700603 strain K61463165.32plasmidpatric1463165
66792Klebsiella quasipneumoniae strain ATCC 700603 strain K61463165.33plasmidpatric1463165
66792Klebsiella quasipneumoniae subsp. similipneumoniae strain ATCC 7006031463164.100completepatric1463164
66792Klebsiella quasipneumoniae ATCC 7006032684623138completeimg1463165
66792Klebsiella pneumoniae K6GCA_025628705contigncbi573
66792Klebsiella pneumoniae K6GCA_025699315scaffoldncbi573

Genome-based predictions

predictions

traitpredictionconfidencetraining_data
spore-formingno100no
flagellatedno93.526no
flagellatedno93.526no
gram-positiveno97.337no
gram-positiveno97.337no
anaerobicno96.141no
anaerobicno96.141no
aerobicyes88.61no
aerobicyes88.61no
halophileno88.825no
halophileno88.825no
spore-formingno92.743no
spore-formingno92.743no
glucose-utilyes94.044no
glucose-utilyes94.044no
motileno81.93no
motileno81.93no
thermophileno99.602yes
thermophileno99.602yes
glucose-fermentyes90.122yes
glucose-fermentyes90.122yes

External links

@ref: 18197

culture collection no.: DSM 26371, ATCC 700603, CCUG 45421, LMG 20218, CIP 110855, NCTC 13368

straininfo link

  • @ref: 74458
  • straininfo: 44033

literature

topicPubmed-IDtitleauthorsjournalDOIyearmeshtopic2
Enzymology10952583Characterization of the extended-spectrum beta-lactamase reference strain, Klebsiella pneumoniae K6 (ATCC 700603), which produces the novel enzyme SHV-18.Rasheed JK, Anderson GJ, Yigit H, Queenan AM, Domenech-Sanchez A, Swenson JM, Biddle JW, Ferraro MJ, Jacoby GA, Tenover FCAntimicrob Agents Chemother10.1128/AAC.44.9.2382-2388.20002000Amino Acid Sequence, Anti-Bacterial Agents/pharmacology, Bacterial Outer Membrane Proteins/genetics/metabolism, Base Sequence, DNA, Bacterial/analysis, Humans, Kinetics, Klebsiella pneumoniae/drug effects/enzymology/*genetics/metabolism, Microbial Sensitivity Tests, Molecular Sequence Data, Nucleic Acid Hybridization, Plasmids/genetics, Polymerase Chain Reaction, beta-Lactam Resistance/*genetics, beta-Lactamases/*genetics/metabolism, beta-LactamsMetabolism
Pathogenicity12239838Prevalence of extended spectrum beta lactamase producing gram negative bacteria in a tertiary care hospital.Mathur P, Kapil A, Das B, Dhawan BIndian J Med Res2002Cross Infection/*epidemiology, Gram-Negative Bacteria/*metabolism, Gram-Negative Bacterial Infections/*epidemiology/*microbiology, Humans, India/epidemiology, Prevalence, beta-Lactamases/*biosynthesisMetabolism
Pathogenicity16871970[Sanfetrinem, the member of trinems--in vitro activity against Klebsiella pneumoniae producing ESBL].Wieczorek P, Sacha PT, Leszczynska K, Jakoniuk P, Zalewska MMed Dosw Mikrobiol2006Anti-Bacterial Agents/*pharmacology, Drug Resistance, Multiple, Bacterial, Hospitals, Humans, Imipenem/pharmacology, Klebsiella Infections/microbiology, Klebsiella pneumoniae/*drug effects/*enzymology/isolation & purification, Lactams/*pharmacology, Microbial Sensitivity Tests, beta-Lactam Resistance, beta-Lactamases/*metabolismEnzymology
Enzymology19459007Activity of the antimicrobial peptide and thanatin analog S-thanatin on clinical isolates of Klebsiella pneumoniae resistant to conventional antibiotics with different structures.Wu GQ, Ding JX, Li LX, Wang HL, Zhao R, Shen ZLCurr Microbiol10.1007/s00284-009-9410-22009Animals, Anti-Bacterial Agents/*pharmacology, Antimicrobial Cationic Peptides/isolation & purification/*pharmacology, *Drug Resistance, Bacterial, Drug Synergism, Heteroptera/chemistry, Klebsiella Infections/*microbiology, Klebsiella pneumoniae/*drug effects/isolation & purification, Microbial Sensitivity Tests, Microbial Viability/drug effects, Peptides, Cyclic/isolation & purification/*pharmacologyPhylogeny
Pathogenicity20084919[Investigation of antibacterial activity of sertralin].Coban AY, Tanriverdi Cayci Y, Keles Uludag S, Durupinar BMikrobiyol Bul2009Anti-Bacterial Agents/*pharmacology, Antidepressive Agents/pharmacology, Bacteria/*drug effects, Humans, Microbial Sensitivity Tests, Serotonin Uptake Inhibitors/pharmacology, Sertraline/*pharmacology
Pathogenicity20455414[Investigation of the in vitro antibacterial effects of statins].Coban AY, Tekeli HO, Guney AK, Durupinar BMikrobiyol Bul2010Atorvastatin, Bacteria/*drug effects, Drug Resistance, Bacterial, Heptanoic Acids/*pharmacology, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors/*pharmacology, Microbial Sensitivity Tests, Pyrroles/*pharmacology, Simvastatin/*pharmacologyEnzymology
Pathogenicity20623220Glucosamine-functionalized silver glyconanoparticles: characterization and antibacterial activity.Veerapandian M, Lim SK, Nam HM, Kuppannan G, Yun KSAnal Bioanal Chem10.1007/s00216-010-3964-52010Anti-Bacterial Agents/*chemistry/*pharmacology, Bacteria/*drug effects, Glucosamine/*chemistry/*pharmacology, Magnetic Resonance Spectroscopy, Microbial Sensitivity Tests, Nanoparticles/*chemistry/ultrastructure, Silver/*chemistry/*pharmacology, Spectrophotometry, Spectrum Analysis, Raman
Enzymology21243821[Research regarding extended-spectrum beta-lactamases produced by enterobacteria strains].Copacianu B, Tuchilus C, Poiata A, Iancu LSRev Med Chir Soc Med Nat Iasi2010Anti-Bacterial Agents/pharmacology, Cephalosporins/pharmacology, Escherichia coli/drug effects/*enzymology, Klebsiella pneumoniae/drug effects/*enzymology, Microbial Sensitivity Tests/*methods, *beta-Lactam Resistance, beta-Lactamases/*metabolismPathogenicity
Pathogenicity22012019Sensitive and specific modified Hodge test for KPC and metallo-beta- lactamase detection in Pseudomonas aeruginosa by use of a novel indicator strain, Klebsiella pneumoniae ATCC 700603.Pasteran F, Veliz O, Rapoport M, Guerriero L, Corso AJ Clin Microbiol10.1128/JCM.05602-112011Anti-Bacterial Agents/*pharmacology, Bacteriological Techniques/*methods, Escherichia coli/drug effects/growth & development, Humans, Klebsiella pneumoniae/*drug effects/*growth & development, Pseudomonas aeruginosa/*enzymology, Sensitivity and Specificity, beta-Lactamases/*metabolism, beta-Lactams/*pharmacologyEnzymology
Pathogenicity22461001In vitro study of elution kinetics and bio-activity of meropenem-loaded acrylic bone cement.Samuel S, Mathew BS, Veeraraghavan B, Fleming DH, Chittaranjan SB, Prakash JAJ Orthop Traumatol10.1007/s10195-012-0191-12012Anti-Bacterial Agents/pharmacology, Bacteria/*drug effects/growth & development, Humans, Meropenem, Microbial Sensitivity Tests, Orthopedic Equipment/*microbiology, Polymethyl Methacrylate/*pharmacology, Prosthesis-Related Infections/microbiology/*prevention & control, Thienamycins/*pharmacologyEnzymology
Pathogenicity22713942Antimicrobial activities of Aerva javanica and Paeonia emodi plants.Mufti FU, Ullah H, Bangash A, Khan N, Hussain S, Ullah F, Jamil M, Jabeen MPak J Pharm Sci2012*Amaranthaceae, Anti-Bacterial Agents/*pharmacology, Antifungal Agents/*pharmacology, Aspergillus/drug effects, Escherichia coli/drug effects, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, *Paeonia, Plant Extracts/*pharmacology, Pseudomonas aeruginosa/drug effects
Pathogenicity22751540In vitro synergy of colistin combinations against colistin-resistant Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae isolates.Vidaillac C, Benichou L, Duval REAntimicrob Agents Chemother10.1128/AAC.05996-112012Acinetobacter baumannii/*drug effects/growth & development/isolation & purification, Anti-Bacterial Agents/*pharmacology, Colistin/*pharmacology, Drug Resistance, Multiple, Bacterial/drug effects, Drug Synergism, Gram-Negative Bacterial Infections/microbiology, Humans, Klebsiella pneumoniae/*drug effects/growth & development/isolation & purification, Microbial Sensitivity Tests, Microbial Viability/drug effects, Pseudomonas aeruginosa/*drug effects/growth & development/isolation & purification, Trimethoprim, Sulfamethoxazole Drug Combination/*pharmacology, Vancomycin/*pharmacologyEnzymology
Pathogenicity22796180N-heterocyclic dicarboxylic acids: broad-spectrum inhibitors of metallo-beta-lactamases with co-antibacterial effect against antibiotic-resistant bacteria.Feng L, Yang KW, Zhou LS, Xiao JM, Yang X, Zhai L, Zhang YL, Crowder MWBioorg Med Chem Lett10.1016/j.bmcl.2012.06.0742012Anti-Bacterial Agents/chemical synthesis/*chemistry/pharmacology, Dicarboxylic Acids/chemical synthesis/*chemistry/pharmacology, Drug Resistance, Bacterial/*drug effects, Enzyme Inhibitors/chemical synthesis/*chemistry/pharmacology, Escherichia coli/drug effects/enzymology, Heterocyclic Compounds/*chemistry, Klebsiella pneumoniae/drug effects/enzymology, Methicillin-Resistant Staphylococcus aureus/drug effects/enzymology, Microbial Sensitivity Tests, *beta-Lactamase Inhibitors, beta-Lactamases/metabolismEnzymology
Pathogenicity23011289Contribution of OqxAB efflux pumps to quinolone resistance in extended-spectrum-beta-lactamase-producing Klebsiella pneumoniae.Rodriguez-Martinez JM, Diaz de Alba P, Briales A, Machuca J, Lossa M, Fernandez-Cuenca F, Rodriguez Bano J, Martinez-Martinez L, Pascual AJ Antimicrob Chemother10.1093/jac/dks3772012Drug Resistance, Bacterial/drug effects/*genetics, *Gene Expression Regulation, Bacterial, Humans, Klebsiella pneumoniae/drug effects/*enzymology/*genetics, Microbial Sensitivity Tests/methods, Quinolones/*pharmacology, beta-Lactamases/biosynthesis/*genetics/isolation & purificationEnzymology
Pathogenicity23923648Antibacterial activity of the recombinant antimicrobial peptide Ib-AMP4 from Impatiens balsamina and its synergy with other antimicrobial agents against drug resistant bacteria.Fan X, Reichling J, Wink MPharmazie2013Anti-Bacterial Agents/*pharmacology, Antimicrobial Cationic Peptides/*metabolism/*pharmacology, Bacteria/drug effects, Culture Media, Drug Resistance, Bacterial, Drug Synergism, Fibroblasts/drug effects, Gram-Positive Bacteria/drug effects, Impatiens/*metabolism, Kinetics, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity TestsMetabolism
Pathogenicity24097361Antibacterial effects of curcumin: An in vitro minimum inhibitory concentration study.Gunes H, Gulen D, Mutlu R, Gumus A, Tas T, Topkaya AEToxicol Ind Health10.1177/07482337134984582013Anti-Bacterial Agents/*pharmacology, Bacillus subtilis/drug effects, Curcumin/*pharmacology, Enterococcus faecalis/drug effects, Escherichia coli/drug effects, Klebsiella pneumoniae/drug effects, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, Pseudomonas aeruginosa/drug effects
24122217Anti-ESBL activity of silver nanoparticles biosynthesized using soil Streptomyces species.Subashini J, Khanna VG, Kannabiran KBioprocess Biosyst Eng10.1007/s00449-013-1070-82014*Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Citrobacter/growth & development, Escherichia coli/growth & development, Klebsiella pneumoniae/growth & development, Metal Nanoparticles/*chemistry, *Silver/chemistry/pharmacology, *Soil Microbiology, Streptomyces/*chemistry
Metabolism25776607Investigation on the conA binding properties of Klebsiella pneumoniae.Anuar AS, Tay STTrop Biomed2014Agglutination, Agglutinins/*metabolism, Animals, Antibodies, Bacterial/immunology, Antigens, Bacterial/chemistry/immunology/isolation & purification/metabolism, Bacterial Proteins/chemistry/immunology/isolation & purification/metabolism, Blotting, Western, Chromatography, Affinity, Concanavalin A/*metabolism, Humans, Klebsiella Infections/microbiology, Klebsiella pneumoniae/isolation & purification/*metabolism, Mass Spectrometry, Molecular Weight, Protein Binding, RabbitsEnzymology
Pathogenicity25777982Multifunctional lanthanide and silver ion co-doped nano-chlorapatites with combined spectroscopic and antimicrobial properties.Wiglusz RJ, Drulis-Kawa Z, Pazik R, Zawisza K, Dorotkiewicz-Jach A, Roszkowiak J, Nedelec JMDalton Trans10.1039/c5dt00046g2015*Anti-Bacterial Agents/chemistry/pharmacology, *Apatites/chemistry/pharmacology, Erbium/chemistry/pharmacology, Escherichia coli/drug effects/growth & development, *Europium/chemistry/pharmacology, Klebsiella pneumoniae/drug effects/growth & development, Microscopy, Electron, Transmission, *Nanoparticles/chemistry/ultrastructure, Pseudomonas aeruginosa/drug effects/growth & development, *Silver/chemistry/pharmacology, Spectrophotometry, Atomic, X-Ray Diffraction, *Ytterbium/chemistry/pharmacology
Pathogenicity26017037Unravelling of a mechanism of resistance to colistin in Klebsiella pneumoniae using atomic force microscopy.Formosa C, Herold M, Vidaillac C, Duval RE, Dague EJ Antimicrob Chemother10.1093/jac/dkv1182015Anti-Bacterial Agents/*pharmacology, Bacterial Capsules/drug effects/ultrastructure, Colistin/*pharmacology, *Drug Resistance, Bacterial, Klebsiella pneumoniae/*drug effects, Microbial Sensitivity Tests, *Microscopy, Atomic Force
Pathogenicity26184804Determining the resistance of carbapenem-resistant Klebsiella pneumoniae to common disinfectants and elucidating the underlying resistance mechanisms.Guo W, Shan K, Xu B, Li JPathog Glob Health10.1179/2047773215Y.00000000222015Anti-Bacterial Agents, Bacteremia/microbiology, Carbapenems/*therapeutic use, Cross Infection/*microbiology/prevention & control, Disinfectants, Drug Resistance, Bacterial/*drug effects, *Hospitals, Humans, Immunocompromised Host/*immunology, Klebsiella Infections/drug therapy/*microbiology/mortality, Klebsiella pneumoniae/*drug effects, Treatment Outcome
26578959S-thanatin functionalized liposome potentially targeting on Klebsiella pneumoniae and its application in sepsis mouse model.Fan X, Fan J, Wang X, Wu P, Wu GFront Pharmacol10.3389/fphar.2015.002492015
26824520gamma-Cyclodextrin capped silver nanoparticles for molecular recognition and enhancement of antibacterial activity of chloramphenicol.Gannimani R, Ramesh M, Mtambo S, Pillay K, Soliman ME, Govender PJ Inorg Biochem10.1016/j.jinorgbio.2016.01.0082016Anti-Bacterial Agents/*pharmacology, Chloramphenicol/*pharmacology, *Metal Nanoparticles, Microscopy, Electron, Scanning, Molecular Dynamics Simulation, Silver/*chemistry, Spectrum Analysis, gamma-Cyclodextrins/*chemistry
Pathogenicity27514961Reduced susceptibility of carbapenem-resistant Klebsiella pneumoniae to biocides: An emerging threat.Bhatia M, Loomba PS, Mishra B, Dogra V, Thakur AIndian J Med Microbiol10.4103/0255-0857.1883452016Aged, Blood/microbiology, Carbapenems/*pharmacology, Cross Infection/*microbiology, Disinfectants/*pharmacology, Disk Diffusion Antimicrobial Tests, *Drug Resistance, Bacterial, Ethanol/pharmacology, Female, Hospitals, Humans, Intensive Care Units, Klebsiella Infections/*microbiology, Klebsiella pneumoniae/*drug effects/isolation & purification, Mucus/microbiology, Povidone-Iodine/pharmacology, Sodium Hypochlorite/pharmacologyEnzymology
Cultivation27554144Potential transfer of extended spectrum beta-lactamase encoding gene, blashv18 gene, between Klebsiella pneumoniae in raw foods.Jung Y, Matthews KRFood Microbiol10.1016/j.fm.2016.06.0022016Animals, Anti-Bacterial Agents/pharmacology, Caseins, Ceftazidime/pharmacology, Child, *Conjugation, Genetic, Culture Media, Drug Resistance, Multiple, Bacterial/*genetics, Escherichia coli/genetics, Food Safety, Humans, Integrases/genetics, Klebsiella pneumoniae/*genetics, Lettuce/microbiology, Microbial Sensitivity Tests, Milk/microbiology, Protein Hydrolysates, Raw Foods/*microbiology, Seedlings/microbiology, beta-Lactamases/*geneticsPathogenicity
Enzymology28364624Biocontrol of the internalization of Salmonella enterica and Enterohaemorrhagic Escherichia coli in mung bean sprouts with an endophytic Bacillus subtilis.Shen Z, Mustapha A, Lin M, Zheng GInt J Food Microbiol10.1016/j.ijfoodmicro.2017.03.0162017Bacillus subtilis/genetics/*metabolism, Biological Control Agents/*metabolism, Chloramphenicol O-Acetyltransferase/genetics, Colony Count, Microbial, Escherichia coli O157/*growth & development/isolation & purification, Food Contamination/*prevention & control, Food Microbiology, Germination, Klebsiella pneumoniae/*growth & development/isolation & purification, Listeria monocytogenes/*growth & development/isolation & purification, Salmonella typhimurium/*growth & development/isolation & purification, Seeds/microbiology, Staphylococcus aureus/*growth & development/isolation & purification, Vegetables/microbiology, Vigna/*microbiologyPhylogeny
Pathogenicity28530185Effect of GNP functionalisation and multiple N-methylation of beta-amyloid residue (32-37) on Gram-positive bacterium.Hemmaragala NM, Abrahamse H, George BPIET Nanobiotechnol10.1049/iet-nbt.2016.00832017Amyloid beta-Peptides/*administration & dosage/chemistry, Cell Survival/*drug effects/physiology, Drug Combinations, Drug Compounding/methods, Gold/*administration & dosage/chemistry, Gram-Negative Bacteria/cytology/*drug effects/physiology, Materials Testing, Metal Nanoparticles/*administration & dosage/*chemistry/ultrastructure, Methylation, Nanoconjugates/administration & dosage/chemistry/ultrastructure, Particle Size, Treatment Outcome
Pathogenicity29143727Characterization of clinically isolated thymidine-dependent small-colony variants of Escherichia coli producing extended-spectrum beta-lactamase.Negishi T, Matsumoto T, Horiuchi K, Kasuga E, Natori T, Matsuoka M, Ogiwara N, Sugano M, Uehara T, Nagano N, Honda TJ Med Microbiol10.1099/jmm.0.0006342017Anti-Bacterial Agents/pharmacology, Drug Resistance, Bacterial/drug effects/genetics, Escherichia coli/drug effects/genetics/*isolation & purification/*metabolism, Escherichia coli Infections/drug therapy/*microbiology, Escherichia coli Proteins/metabolism, Humans, Japan, Klebsiella Infections/drug therapy/microbiology, Klebsiella pneumoniae/drug effects/genetics/isolation & purification/metabolism, Mutation/genetics, Plasmids/genetics, Thymidine/*metabolism, beta-Lactamases/*metabolismMetabolism
Pathogenicity29216563Synthesis and antimicrobial activity of amino acid and peptide derivatives of mycophenolic acid.Siebert A, Wysocka M, Krawczyk B, Cholewinski G, Rachon JEur J Med Chem10.1016/j.ejmech.2017.11.0942017Amino Acids/chemistry/*pharmacology, Anti-Bacterial Agents/chemical synthesis/chemistry/*pharmacology, Dose-Response Relationship, Drug, Escherichia coli/drug effects, Klebsiella pneumoniae/drug effects, Microbial Sensitivity Tests, Molecular Structure, Mycophenolic Acid/chemical synthesis/chemistry/*pharmacology, Peptides/chemistry/*pharmacology, Pseudomonas aeruginosa/drug effects, Staphylococcus aureus/drug effects, Structure-Activity Relationship
Pathogenicity29462537[In vitro antibacterial activity of Curcuma longa (Zingiberaceae) against nosocomial bacteria in Monteria, Colombia].Mendez Alvarez N, Angulo Ortiz A, Contreras Martinez ORev Biol Trop2016Anti-Bacterial Agents/*pharmacology, Bacteria/*drug effects/growth & development, Colombia, Cross Infection/*microbiology/prevention & control, Curcuma/*chemistry, Enzyme-Linked Immunosorbent Assay, Ethanol/chemistry, Formazans, Microbial Sensitivity Tests, Oils, Volatile/pharmacology, Plant Extracts/*pharmacology, Reproducibility of Results, Tetrazolium Salts
Pathogenicity29603034Development of EUCAST zone diameter breakpoints and quality control criteria for ceftazidime-avibactam 10-4 mug.Koeth LM, Matuschek E, Kahlmeter G, Stone GEur J Clin Microbiol Infect Dis10.1007/s10096-018-3215-92018Anti-Bacterial Agents/*pharmacology, Azabicyclo Compounds/*pharmacology, Ceftazidime/*pharmacology, Disk Diffusion Antimicrobial Tests/instrumentation/*methods, Drug Combinations, Enterobacteriaceae/*drug effects, Escherichia coli/drug effects, Humans, Klebsiella pneumoniae/drug effects, Pseudomonas aeruginosa/drug effects, Quality Control, beta-Lactamases/drug effects
30538974High-Temperature Short-Time Treatment of Human Milk for Bacterial Count Reduction.Klotz D, Schreiner M, Falcone V, Jonas D, Kunze M, Weber A, Fuchs H, Hentschel RFront Pediatr10.3389/fped.2018.003592018
Pathogenicity30561174Isothiazolopyridine Mannich bases and their antibacterial effect.Swiatek P, Strzelecka MAdv Clin Exp Med10.17219/acem/993102019Anti-Bacterial Agents/*pharmacology, Bacteria/*drug effects, Humans, Mannich Bases/*pharmacology, Microbial Sensitivity Tests, Spectroscopy, Fourier Transform Infrared
Pathogenicity30630320Antimicrobial effect of novel hydrogel matrix based on natural polysaccharide Sterculia urens.Lipovy B, Holoubek J, Vacek L, Ruzicka F, Nedomova E, Postulkova H, Vojtova LEpidemiol Mikrobiol Imunol107027*Anti-Infective Agents/pharmacology, *Bacteria/drug effects, *Hydrogels/chemistry, Microbial Sensitivity Tests, *Polysaccharides/pharmacology, *Sterculia/chemistry
Phylogeny30886188Uncovering the potential of novel micromonosporae isolated from an extreme hyper-arid Atacama Desert soil.Carro L, Castro JF, Razmilic V, Nouioui I, Pan C, Igual JM, Jaspars M, Goodfellow M, Bull AT, Asenjo JA, Klenk HPSci Rep10.1038/s41598-019-38789-z2019Anti-Infective Agents/*isolation & purification/therapeutic use, Antineoplastic Agents/*isolation & purification/therapeutic use, Cell Extracts, Chile, Desert Climate, Drug Discovery, Hep G2 Cells, Humans, Klebsiella Infections/*therapy, Klebsiella pneumoniae/*physiology, Liver Neoplasms/*therapy, Methanol/*isolation & purification, Micromonospora/*physiology, Phylogeny, Soil Microbiology, Streptomyces/physiology, Stress, Physiological/geneticsEnzymology
30905995A Comparison of Bacterial Adhesion and Biofilm Formation on Commonly Used Orthopaedic Metal Implant Materials: An In vitro Study.Malhotra R, Dhawan B, Garg B, Shankar V, Nag TCIndian J Orthop10.4103/ortho.IJOrtho_66_182019
Pathogenicity31167844Development of Broth Microdilution MIC and Disk Diffusion Antimicrobial Susceptibility Test Quality Control Ranges for the Combination of Cefepime and the Novel beta-Lactamase Inhibitor Enmetazobactam.Belley A, Huband MD, Fedler KA, Watters AA, Flamm RK, Shapiro S, Knechtle PJ Clin Microbiol10.1128/JCM.00607-192019Anti-Bacterial Agents/*pharmacology, Azabicyclo Compounds/*pharmacology, Cefepime/*pharmacology, Disk Diffusion Antimicrobial Tests/*methods/standards, Enterobacteriaceae/*drug effects, Microbial Sensitivity Tests/standards, *Quality Control, Triazoles/*pharmacology, beta-Lactamase Inhibitors/*pharmacology
31198423Determination of In Vitro Antimicrobial Activity of Five Sri Lankan Medicinal Plants against Selected Human Pathogenic Bacteria.De Zoysa MHN, Rathnayake H, Hewawasam RP, Wijayaratne WMDGBInt J Microbiol10.1155/2019/74314392019
31600969Clarithromycin-Loaded Poly (Lactic-co-glycolic Acid) (PLGA) Nanoparticles for Oral Administration: Effect of Polymer Molecular Weight and Surface Modification with Chitosan on Formulation, Nanoparticle Characterization and Antibacterial Effects.Ozturk AA, Yenilmez E, Ozarda MGPolymers (Basel)10.3390/polym111016322019
32128281Antimicrobial activities of Tephrosia vogelii against selected pathogenic fungi and bacteria strains.Mlozi SH, Mmongoyo JA, Chacha MMycology10.1080/21501203.2019.17059292019
Phylogeny32300363Isolation, Characterization, and Screening of Antimicrobial-Producing Actinomycetes from Soil Samples.Sapkota A, Thapa A, Budhathoki A, Sainju M, Shrestha P, Aryal SInt J Microbiol10.1155/2020/27165842020
32308717Antimicrobial Evaluation of Latex and TLC Fractions from the Leaves of Aloe adigratana Reynolds.Asmerom D, Hailu GS, Yimer EM, Bitew H, Kahsay GEvid Based Complement Alternat Med10.1155/2020/83124712020
Enzymology32486455Bioassay Guided Isolation and Docking Studies of a Potential beta-Lactamase Inhibitor from Clutia myricoides.Elfaky MA, El-Halawany AM, Koshak AE, Alshali KZ, El-Araby ME, Khayat MT, Abdallah HMMolecules10.3390/molecules251125662020Anti-Bacterial Agents/pharmacology, Binding Sites, Biological Assay, Cephalosporins/chemistry, Chloroform/chemistry, Escherichia coli/drug effects/enzymology, Furans/chemistry, Klebsiella pneumoniae/drug effects/enzymology, Magnetic Resonance Spectroscopy, Magnoliopsida/*chemistry, Microbial Sensitivity Tests, Models, Molecular, Molecular Docking Simulation, Protein Binding, beta-Lactamase Inhibitors/*chemistry/pharmacology, beta-Lactamases/*chemistryPathogenicity
Metabolism32652494Phenotypical and molecular assessment of the virulence potential of KPC-3-producing Klebsiella pneumoniae ST392 clinical isolates.D'Apolito D, Arena F, Conte V, De Angelis LH, Di Mento G, Carreca AP, Cuscino N, Russelli G, Iannolo G, Barbera F, Pasqua S, Monaco F, Cardinale F, Rossolini GM, Conaldi PG, Douradinha BMicrobiol Res10.1016/j.micres.2020.1265512020Animals, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/genetics/*metabolism, Biofilms, Cross Infection/microbiology, Drug Resistance, Multiple, Bacterial/genetics, HT29 Cells, Humans, Italy, Klebsiella, Klebsiella pneumoniae/drug effects/genetics/*isolation & purification/*metabolism, Larva, Microbial Sensitivity Tests, *Phenotype, Polysaccharides, Bacterial/metabolism, Virulence, beta-Lactamases/genetics/*metabolismPathogenicity
32655515Rapid Detection to Differentiate Hypervirulent Klebsiella pneumoniae (hvKp) From Classical K. pneumoniae by Identifying peg-344 With Loop-Mediated Isothermal Amplication (LAMP).Liao W, Long D, Huang Q, Wei D, Liu X, Wan L, Feng Y, Zhang W, Liu YFront Microbiol10.3389/fmicb.2020.011892020
33134573Nutraceutical and antimicrobial potentials of Bambara groundnut (Vigna subterranean): A review.Udeh EL, Nyila MA, Kanu SAHeliyon10.1016/j.heliyon.2020.e052052020
Phylogeny33162956Antimicrobial Potential of Streptomyces ansochromogenes (PB3) Isolated From a Plant Native to the Amazon Against Pseudomonas aeruginosa.Amorim EADF, Castro EJM, da Souza SV, Alves MS, Dias LRL, Melo MHF, da Silva IMA, Villis PCM, Bonfim MRQ, Falcai A, Silva MRC, Monteiro-Neto V, Alianca A, da Silva LCN, de Miranda RCMFront Microbiol10.3389/fmicb.2020.5746932020
Pathogenicity33390165Antibacterial activity of methanol extracts of the leaves of three medicinal plants against selected bacteria isolated from wounds of lymphoedema patients.Nigussie D, Davey G, Legesse BA, Fekadu A, Makonnen EBMC Complement Med Ther10.1186/s12906-020-03183-02021Achyranthes/chemistry, Anti-Bacterial Agents/*analysis, Azadirachta/chemistry, Humans, Lawsonia Plant/chemistry, Lymphedema/complications/*microbiology, Microbial Sensitivity Tests, Plant Extracts/*chemistry/therapeutic use, Plants, Medicinal/*chemistry, Wound Infection/drug therapy/*microbiologyPhylogeny
33459199Enhancing bactericidal strategy with selected aromatic compounds: in vitro and in silico study.Oztekin A, Karagoz K, Adem S, Comakli VJ Biomol Struct Dyn10.1080/07391102.2021.18718642021
Phylogeny33597879Antibacterial Activities of Echinops kebericho Mesfin Tuber Extracts and Isolation of the Most Active Compound, Dehydrocostus Lactone.Deyno S, Mtewa AG, Hope D, Bazira J, Makonnen E, Alele PEFront Pharmacol10.3389/fphar.2020.6086722021
Pathogenicity33616480Development and characterization of lyophilized cefpodoxime proxetil-Pluronic((R)) F127/polyvinylpyrrolidone K30 solid dispersions with improved dissolution and enhanced antibacterial activity.Yurtdas-Kirimlioglu GPharm Dev Technol10.1080/10837450.2021.18895842021Anti-Bacterial Agents/*administration & dosage/chemistry/pharmacology, Bacteria/*drug effects, Capsules, Ceftizoxime/administration & dosage/*analogs & derivatives/chemistry/pharmacology, Chemistry, Pharmaceutical/methods, Drug Carriers/*chemistry, Drug Liberation, Freeze Drying, Microbial Sensitivity Tests, Particle Size, Poloxamer/chemistry, Povidone/analogs & derivatives/chemistry, Solubility, Wettability
34335776Determination of the Chemical Composition and Antimicrobial Activity of Lavatera thuringiaca L. Medicinal Herb Material Extracted under Subcritical Conditions by the Liquid Carbon Dioxide Method.Zhandabayeva MA, Kozhanova KK, Boshkayeva AK, Kataev VA, Ustenova GO, Gemejiyeva NG, Iskakbayeva ZAInt J Biomater10.1155/2021/75415552021
Pathogenicity34343655Antioxidant and antibacterial study of 10 flavonoids revealed rutin as a potential antibiofilm agent in Klebsiella pneumoniae strains isolated from hospitalized patients.Wang Z, Ding Z, Li Z, Ding Y, Jiang F, Liu JMicrob Pathog10.1016/j.micpath.2021.1051212021Anti-Bacterial Agents/pharmacology/therapeutic use, *Antioxidants, Biofilms, Escherichia coli, Flavonoids/pharmacology, Humans, *Klebsiella pneumoniae, Rutin/pharmacology
34718011Antimicrobial and antifungal properties of NiCu-PANI/PVA quaternary nanocomposite synthesized by chemical oxidative polymerization of polyaniline.Laourari I, Lakhdari N, Belgherbi O, Medjili C, Berkani M, Vasseghian Y, Golzadeh N, Lakhdari DChemosphere10.1016/j.chemosphere.2021.1326962021Aniline Compounds, Anti-Bacterial Agents/pharmacology, *Anti-Infective Agents, Antifungal Agents/pharmacology, Gram-Negative Bacteria, Gram-Positive Bacteria, Microbial Sensitivity Tests, *Nanocomposites, Oxidative Stress, Polymerization
Pathogenicity34784023Efficacy and mechanism of carvacrol with octanoic acid against mastitis causing multi-drug-resistant pathogens.Rani S, Singh H, Ram CBraz J Microbiol10.1007/s42770-021-00639-42021Animals, Anti-Bacterial Agents/pharmacology, Caprylates/pharmacology, Cattle, Cymenes, Escherichia coli, Female, Humans, *Mastitis, Microbial Sensitivity Tests, *Oils, Volatile/pharmacology, *Pharmaceutical Preparations
Pathogenicity35269342Loaded n-Hydroxyapatite/SSG 3D Scaffolds as a Drug Delivery System of Nigella sativa Fractions for the Management of Local Antibacterial Infections.Dalli M, El Guerraf A, Azizi SE, Benataya K, Azghar A, Mi-Kyung J, Maleb A, Bonglee K, Gseyra NNanomaterials (Basel)10.3390/nano120508562022
35595177Nosocomial transmission and rearrangement of large resistance-virulence hybrid plasmids between two bacteremic ST11 carbapenem-resistant hypervirulent Klebsiella pneumoniae strains with low fitness cost.Liao W, Huang QS, Wei D, Xiong Z, Du FL, Xiang TX, Zhang S, Wan LG, Zhang W, Liu YMicrob Pathog10.1016/j.micpath.2022.1055932022
35967858Genetic characterization and passage instability of a novel hybrid virulence plasmid in a ST23 hypervirulent Klebsiella pneumoniae.Fan LP, Yu Y, Huang S, Liao W, Huang QS, Du FL, Xiang TX, Wei DD, Wan LG, Zhang W, Liu YFront Cell Infect Microbiol10.3389/fcimb.2022.8707792022Animals, Escherichia coli/genetics, *Klebsiella Infections/microbiology, *Klebsiella pneumoniae/genetics, Mice, Plasmids/genetics, Virulence/genetics, Virulence Factors/genetics
36296456Antimicrobial Activity of Silver and Gold Nanoparticles Prepared by Photoreduction Process with Leaves and Fruit Extracts of Plinia cauliflora and Punica granatum.Franzolin MR, Courrol DDS, Silva FRO, Courrol LCMolecules10.3390/molecules272068602022Silver/pharmacology/chemistry, Gold/pharmacology, *Metal Nanoparticles/chemistry, *Pomegranate, Fruit, *Methicillin-Resistant Staphylococcus aureus, Excipients, Microbial Sensitivity Tests, *Anti-Infective Agents/pharmacology/chemistry, *Lythraceae, Anti-Bacterial Agents/pharmacology, Escherichia coli, Gram-Positive Bacteria, *Myrtaceae, Plant Extracts/pharmacology/chemistry, Plant Leaves

Reference

@idauthorscataloguedoi/urltitle
18197Curators of the DSMZLeibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 26371)https://www.dsmz.de/collection/catalogue/details/culture/DSM-26371
20215Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.10.1099/ijsem.0.004332List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ
41591Curators of the CIPhttps://brclims.pasteur.fr/brcWeb/souche/detail/1/34409
56773Curators of the CCUGCulture Collection University of Gothenburg (CCUG) (CCUG 45421)https://www.ccug.se/strain?id=45421
66792Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmannhttps://diaspora-project.de/progress.html#genomesAutomatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)
68368Automatically annotated from API 20E
68374Automatically annotated from API ID32E
69480Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmannhttps://diaspora-project.de/progress.html#genomesPredictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)
69481Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch10.21203/rs.3.rs-2527258/v1Predictions based on the model GenomeNet Sporulation v. 1
74458Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.10.60712/SI-ID44033.1StrainInfo: A central database for resolving microbial strain identifiers
122107Curators of the CIPCollection of Institut Pasteur (CIP 110855)https://catalogue-crbip.pasteur.fr/fiche_catalogue.xhtml?crbip=CIP%20110855