Strain identifier
BacDive ID: 4948
Type strain:
Species: Klebsiella pneumoniae
Strain Designation: 240
Strain history: CIP <- 1993, NCIMB <- NCTC, Klebsiella aerogenes <- C.E.H. Winslow AMNH <- J. Hopkins Hosp., UK
NCBI tax ID(s): 573 (species)
General
@ref: 959
BacDive-ID: 4948
DSM-Number: 2026
keywords: genome sequence, Bacteria, facultative anaerobe, mesophilic, Gram-negative, human pathogen
description: Klebsiella pneumoniae 240 is a facultative anaerobe, mesophilic, Gram-negative human pathogen of the family Enterobacteriaceae.
NCBI tax id
- NCBI tax id: 573
- Matching level: species
strain history
@ref | history |
---|---|
959 | <- NCIB <- NCTC (Klebsiella aerogenes) <- C.W. Winslow <- John Hopkins Hosp., 240 |
121883 | CIP <- 1993, NCIMB <- NCTC, Klebsiella aerogenes <- C.E.H. Winslow AMNH <- J. Hopkins Hosp., UK |
doi: 10.13145/bacdive4948.20230509.8.1
Name and taxonomic classification
LPSN
- @ref: 20215
- description: domain/bacteria
- keyword: phylum/pseudomonadota
- domain: Bacteria
- phylum: Pseudomonadota
- class: Gammaproteobacteria
- order: Enterobacterales
- family: Enterobacteriaceae
- genus: Klebsiella
- species: Klebsiella pneumoniae
- full scientific name: Klebsiella pneumoniae (Schroeter 1886) Trevisan 1887 (Approved Lists 1980)
synonyms
- @ref: 20215
- synonym: Hyalococcus pneumoniae
@ref: 959
domain: Bacteria
phylum: Proteobacteria
class: Gammaproteobacteria
order: Enterobacteriales, not validated
family: Enterobacteriaceae
genus: Klebsiella
species: Klebsiella pneumoniae
full scientific name: Klebsiella pneumoniae (Schroeter 1886) Trevisan 1887
strain designation: 240
type strain: no
Morphology
cell morphology
@ref | gram stain | confidence | cell shape | motility |
---|---|---|---|---|
69480 | negative | 99.963 | ||
121883 | negative | rod-shaped | no |
Culture and growth conditions
culture medium
@ref | name | growth | link | composition |
---|---|---|---|---|
959 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | yes | https://mediadive.dsmz.de/medium/693 | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base |
959 | NUTRIENT AGAR (DSMZ Medium 1) | yes | https://mediadive.dsmz.de/medium/1 | Name: NUTRIENT AGAR (DSMZ Medium 1) Composition: Agar 15.0 g/l Peptone 5.0 g/l Meat extract 3.0 g/l Distilled water |
35132 | MEDIUM 3 - Columbia agar | yes | Columbia agar (39.000 g);distilled water (1000.000 ml) | |
121883 | CIP Medium 3 | yes | https://catalogue-crbip.pasteur.fr/fiche_milieu.xhtml?crbip=3 |
culture temp
@ref | growth | type | temperature | range |
---|---|---|---|---|
959 | positive | growth | 37 | mesophilic |
35132 | positive | growth | 30 | mesophilic |
121883 | positive | growth | 30-41 | |
121883 | no | growth | 5 | psychrophilic |
121883 | no | growth | 10 | psychrophilic |
Physiology and metabolism
oxygen tolerance
- @ref: 121883
- oxygen tolerance: facultative anaerobe
spore formation
@ref | spore formation | confidence |
---|---|---|
69481 | no | 100 |
69480 | no | 99.906 |
compound production
@ref | compound |
---|---|
959 | bacteriocin |
959 | 1,3 propanediol |
959 | 1,3 propanediol oxidoreductase |
metabolite utilization
@ref | metabolite | utilization activity | kind of utilization tested | Chebi-ID |
---|---|---|---|---|
68371 | Potassium 5-ketogluconate | - | builds acid from | |
68371 | Potassium 2-ketogluconate | - | builds acid from | |
68371 | gluconate | + | builds acid from | 24265 |
68371 | L-arabitol | - | builds acid from | 18403 |
68371 | D-arabitol | + | builds acid from | 18333 |
68371 | L-fucose | + | builds acid from | 18287 |
68371 | D-fucose | - | builds acid from | 28847 |
68371 | D-tagatose | - | builds acid from | 16443 |
68371 | D-lyxose | - | builds acid from | 62318 |
68371 | gentiobiose | + | builds acid from | 28066 |
68371 | xylitol | - | builds acid from | 17151 |
68371 | starch | + | builds acid from | 28017 |
68371 | raffinose | + | builds acid from | 16634 |
68371 | melezitose | - | builds acid from | 6731 |
68371 | inulin | - | builds acid from | 15443 |
68371 | trehalose | + | builds acid from | 27082 |
68371 | sucrose | + | builds acid from | 17992 |
68371 | melibiose | + | builds acid from | 28053 |
68371 | lactose | + | builds acid from | 17716 |
68371 | maltose | + | builds acid from | 17306 |
68371 | cellobiose | + | builds acid from | 17057 |
68371 | salicin | + | builds acid from | 17814 |
68371 | esculin | + | builds acid from | 4853 |
68371 | arbutin | + | builds acid from | 18305 |
68371 | N-acetylglucosamine | + | builds acid from | 59640 |
68371 | methyl alpha-D-glucopyranoside | + | builds acid from | 320061 |
68371 | methyl alpha-D-mannoside | - | builds acid from | 43943 |
68371 | D-sorbitol | + | builds acid from | 17924 |
68371 | D-mannitol | + | builds acid from | 16899 |
68371 | myo-inositol | + | builds acid from | 17268 |
68371 | galactitol | - | builds acid from | 16813 |
68371 | L-rhamnose | + | builds acid from | 62345 |
68371 | L-sorbose | + | builds acid from | 17266 |
68371 | D-mannose | + | builds acid from | 16024 |
68371 | D-fructose | + | builds acid from | 15824 |
68371 | D-glucose | + | builds acid from | 17634 |
68371 | D-galactose | + | builds acid from | 12936 |
68371 | methyl beta-D-xylopyranoside | - | builds acid from | 74863 |
68371 | ribitol | + | builds acid from | 15963 |
68371 | L-xylose | - | builds acid from | 65328 |
68371 | D-xylose | + | builds acid from | 65327 |
68371 | D-ribose | + | builds acid from | 16988 |
68371 | L-arabinose | + | builds acid from | 30849 |
68371 | D-arabinose | - | builds acid from | 17108 |
68371 | erythritol | - | builds acid from | 17113 |
68371 | glycerol | + | builds acid from | 17754 |
68368 | L-arabinose | + | fermentation | 30849 |
68368 | amygdalin | + | fermentation | 27613 |
68368 | melibiose | + | fermentation | 28053 |
68368 | sucrose | + | fermentation | 17992 |
68368 | L-rhamnose | + | fermentation | 62345 |
68368 | sorbitol | + | fermentation | 30911 |
68368 | myo-inositol | + | fermentation | 17268 |
68368 | D-mannitol | + | fermentation | 16899 |
68368 | D-glucose | + | fermentation | 17634 |
68368 | gelatin | - | hydrolysis | 5291 |
68368 | tryptophan | - | energy source | 27897 |
68368 | urea | + | hydrolysis | 16199 |
68368 | citrate | + | assimilation | 16947 |
68368 | ornithine | - | degradation | 18257 |
68368 | arginine | - | hydrolysis | 29016 |
121883 | mannitol | + | fermentation | 29864 |
121883 | citrate | + | carbon source | 16947 |
121883 | glucose | + | fermentation | 17234 |
121883 | lactose | + | fermentation | 17716 |
121883 | nitrate | + | reduction | 17632 |
121883 | nitrite | - | reduction | 16301 |
121883 | malonate | + | assimilation | 15792 |
121883 | sodium thiosulfate | - | builds gas from | 132112 |
121883 | glucose | + | degradation | 17234 |
antibiotic resistance
- @ref: 121883
- metabolite: 0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate)
- is antibiotic: yes
- is sensitive: no
- is resistant: yes
metabolite production
@ref | Chebi-ID | metabolite | production |
---|---|---|---|
68368 | 15688 | acetoin | yes |
68368 | 35581 | indole | no |
68368 | 16136 | hydrogen sulfide | no |
121883 | 35581 | indole | no |
metabolite tests
@ref | Chebi-ID | metabolite | voges-proskauer-test | indole test | methylred-test |
---|---|---|---|---|---|
68368 | 15688 | acetoin | + | ||
68368 | 35581 | indole | - | ||
121883 | 15688 | acetoin | + | ||
121883 | 17234 | glucose | - |
enzymes
@ref | value | activity | ec |
---|---|---|---|
68382 | alpha-fucosidase | - | 3.2.1.51 |
68382 | alpha-mannosidase | - | 3.2.1.24 |
68382 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 |
68382 | beta-glucosidase | - | 3.2.1.21 |
68382 | alpha-glucosidase | - | 3.2.1.20 |
68382 | beta-glucuronidase | - | 3.2.1.31 |
68382 | beta-galactosidase | - | 3.2.1.23 |
68382 | alpha-galactosidase | - | 3.2.1.22 |
68382 | naphthol-AS-BI-phosphohydrolase | - | |
68382 | acid phosphatase | - | 3.1.3.2 |
68382 | alpha-chymotrypsin | - | 3.4.21.1 |
68382 | trypsin | - | 3.4.21.4 |
68382 | cystine arylamidase | - | 3.4.11.3 |
68382 | valine arylamidase | - | |
68382 | leucine arylamidase | - | 3.4.11.1 |
68382 | lipase (C 14) | - | |
68382 | esterase lipase (C 8) | - | |
68382 | esterase (C 4) | - | |
68382 | alkaline phosphatase | - | 3.1.3.1 |
68368 | cytochrome oxidase | - | 1.9.3.1 |
68368 | gelatinase | - | |
68368 | tryptophan deaminase | - | 4.1.99.1 |
68368 | urease | + | 3.5.1.5 |
68368 | ornithine decarboxylase | - | 4.1.1.17 |
68368 | arginine dihydrolase | - | 3.5.3.6 |
68368 | beta-galactosidase | + | 3.2.1.23 |
121883 | oxidase | - | |
121883 | beta-galactosidase | + | 3.2.1.23 |
121883 | alcohol dehydrogenase | - | 1.1.1.1 |
121883 | gelatinase | - | |
121883 | catalase | + | 1.11.1.6 |
121883 | lysine decarboxylase | + | 4.1.1.18 |
121883 | ornithine decarboxylase | - | 4.1.1.17 |
121883 | tryptophan deaminase | - | |
121883 | urease | + | 3.5.1.5 |
API zym
@ref | Control | Alkaline phosphatase | Esterase | Esterase Lipase | Lipase | Leucine arylamidase | Valine arylamidase | Cystine arylamidase | Trypsin | alpha- Chymotrypsin | Acid phosphatase | Naphthol-AS-BI-phosphohydrolase | alpha- Galactosidase | beta- Galactosidase | beta- Glucuronidase | alpha- Glucosidase | beta- Glucosidase | N-acetyl-beta- glucosaminidase | alpha- Mannosidase | alpha- Fucosidase |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
121883 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
API 20E
@ref | ONPG | ADH Arg | LDC Lys | ODC | CIT | H2S | URE | TDA Trp | IND | VP | GEL | GLU | MAN | INO | Sor | RHA | SAC | MEL | AMY | ARA | OX |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
959 | + | - | +/- | - | + | - | + | - | - | + | - | + | + | + | + | + | + | + | + | + | - |
959 | + | - | + | - | + | - | + | - | - | + | - | + | + | + | + | + | + | + | + | + | - |
API 50CHac
@ref | GLY | ERY | DARA | LARA | RIB | DXYL | LXYL | ADO | MDX | GAL | GLU | FRU | MNE | SBE | RHA | DUL | INO | MAN | SOR | MDM | MDG | NAG | AMY | ARB | ESC | SAL | CEL | MAL | LAC | MEL | SAC | TRE | INU | MLZ | RAF | AMD | GLYG | XLT | GEN | TUR | LYX | TAG | DFUC | LFUC | DARL | LARL | GNT | 2KG | 5KG |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
121883 | + | - | - | + | + | + | - | + | - | + | + | + | + | + | + | - | + | + | + | - | + | + | +/- | + | + | + | + | + | + | + | + | + | - | - | + | + | +/- | - | + | +/- | - | - | - | + | + | - | + | - | - |
Isolation, sampling and environmental information
isolation
- @ref: 121883
- isolation date: 1911
Safety information
risk assessment
@ref | pathogenicity human | pathogenicity animal | biosafety level | biosafety level comment |
---|---|---|---|---|
959 | yes | yes | 2 | Risk group (German classification) |
121883 | 2 | Risk group (French classification) |
Sequence information
Genome sequences
@ref | description | accession | assembly level | database | NCBI tax ID |
---|---|---|---|---|---|
66792 | Klebsiella pneumoniae NCTC418 | GCA_900635995 | complete | ncbi | 573 |
66792 | Klebsiella pneumoniae 240 | GCA_019336325 | contig | ncbi | 573 |
66792 | Klebsiella pneumoniae DSM 2026 | GCA_000949515 | contig | ncbi | 573 |
66792 | Klebsiella pneumoniae NCTC 418 | GCA_003076915 | chromosome | ncbi | 573 |
66792 | Klebsiella aerogenes strain NCTC418 | 548.407 | complete | patric | 548 |
66792 | Klebsiella pneumoniae strain DSM 2026 | 573.1480 | wgs | patric | 573 |
66792 | Klebsiella pneumoniae strain NCTC 418 | 573.18084 | complete | patric | 573 |
66792 | Klebsiella pneumoniae subsp. pneumoniae Ecl8 | 1226680.3 | wgs | patric | 1226680 |
66792 | Klebsiella aerogenes NCTC418 | 2922810722 | complete | img | 548 |
66792 | Klebsiella pneumoniae DSM 2026 | 2740892456 | draft | img | 573 |
Genome-based predictions
predictions
trait | prediction | confidence | training_data |
---|---|---|---|
spore-forming | no | 100 | no |
flagellated | no | 93.064 | no |
gram-positive | no | 96.998 | no |
anaerobic | no | 95.883 | no |
aerobic | yes | 87.194 | no |
halophile | no | 88.663 | no |
spore-forming | no | 92.425 | no |
thermophile | no | 99.623 | yes |
glucose-util | yes | 94.485 | no |
motile | no | 84.374 | no |
glucose-ferment | yes | 91.353 | no |
External links
@ref: 959
culture collection no.: DSM 2026, ATCC 15380, NCIB 418, NCTC 418, CIP 103733, NCDO 711, NCTC 240
straininfo link
- @ref: 74444
- straininfo: 45585
literature
topic | Pubmed-ID | title | authors | journal | DOI | year | mesh | topic2 |
---|---|---|---|---|---|---|---|---|
Metabolism | 1593257 | Anaerobic 2-ketogluconate metabolism of Klebsiella pneumoniae NCTC 418 grown in chemostat culture: involvement of the pentose phosphate pathway. | Simons JA, Snoep JL, Feitz S, Teixeira de Mattos MJ, Neijssel OM | J Gen Microbiol | 10.1099/00221287-138-3-423 | 1992 | Adenosine Triphosphate/metabolism, Anaerobiosis, Cell Division, Culture Media, Enzymes/analysis, Gluconates/*metabolism, Hydrogen-Ion Concentration, Klebsiella pneumoniae/*metabolism, NADP/metabolism, Pentose Phosphate Pathway/*physiology | Cultivation |
Metabolism | 1659609 | Aerobic 2-ketogluconate metabolism of Klebsiella pneumoniae NCTC 418 grown in chemostat culture. | Simons JA, Teixeira de Mattos MJ, Neijssel OM | J Gen Microbiol | 10.1099/00221287-137-7-1479 | 1991 | Adenosine Triphosphate/metabolism, Aerobiosis, Carbohydrate Dehydrogenases/biosynthesis/*metabolism, Cell Fractionation, Gluconates/*metabolism, Kinetics, Klebsiella pneumoniae/growth & development/*metabolism, NADP/metabolism, Phosphotransferases/metabolism, *Phosphotransferases (Alcohol Group Acceptor) | Enzymology |
1768141 | Utility of phenomenological models for describing temperature dependence of bacterial growth. | Heitzer A, Kohler HP, Reichert P, Hamer G | Appl Environ Microbiol | 10.1128/aem.57.9.2656-2665.1991 | 1991 | Bacteria/*growth & development, DNA Damage, DNA Repair, Models, Biological, *Models, Theoretical, *Temperature | ||
Enzymology | 2160228 | The role of magnesium and calcium ions in the glucose dehydrogenase activity of Klebsiella pneumoniae NCTC 418. | Buurman ET, Boiardi JL, Teixeira de Mattos MJ, Neijssel OM | Arch Microbiol | 10.1007/BF00248434 | 1990 | Calcium/*physiology, Carbohydrate Dehydrogenases/*metabolism, Culture Media, Glucose 1-Dehydrogenase, Glucose Dehydrogenases/*metabolism, Klebsiella pneumoniae/*enzymology, Magnesium/*physiology, PQQ Cofactor, Quinolones/pharmacology | Metabolism |
Cultivation | 2185712 | Recovery of exponentially growing cultures of Klebsiella pneumoniae NCIB 418 after heat shocks. | Heitzer A, Hamer G | Arch Microbiol | 10.1007/BF00249081 | 1990 | Colony Count, Microbial, Culture Media, Glucose/metabolism, *Hot Temperature, Kinetics, Klebsiella pneumoniae/*growth & development | Stress |
Metabolism | 2187428 | Quantification of multiple-substrate controlled growth--simultaneous ammonium and glucose limitation in chemostat cultures of Klebsiella pneumoniae. | Rutgers M, Balk PA, van Dam K | Arch Microbiol | 10.1007/BF00248430 | 1990 | Ammonium Chloride/*metabolism, Culture Media, Glucose/*metabolism, Kinetics, Klebsiella pneumoniae/*growth & development/metabolism | Cultivation |
Enzymology | 2539792 | The separate roles of PQQ and apo-enzyme syntheses in the regulation of glucose dehydrogenase activity in Klebsiella pneumoniae NCTC 418. | Hommes RW, Herman PT, Postma PW, Tempest DW, Neijssel OM | Arch Microbiol | 10.1007/BF00413139 | 1989 | Aerobiosis, Anaerobiosis, Apoenzymes/*biosynthesis, Apoproteins/*biosynthesis, Carbohydrate Dehydrogenases/*metabolism, Carbon Dioxide/metabolism, Coenzymes/*biosynthesis, Gluconates/biosynthesis, Glucose/metabolism, Glucose Dehydrogenases/biosynthesis/*metabolism, Klebsiella pneumoniae/*enzymology/growth & development, Oxygen Consumption, PQQ Cofactor, Quinolones/*biosynthesis | Metabolism |
Enzymology | 2650650 | The influence of the culture pH value on the direct glucose oxidative pathway in Klebsiella pneumoniae NCTC 418. | Hommes RW, Postma PW, Tempest DW, Neijssel OM | Arch Microbiol | 10.1007/BF00413140 | 1989 | Aerobiosis, Carbohydrate Dehydrogenases/biosynthesis/metabolism, Culture Media, Gluconates/biosynthesis, Glucose/*metabolism, Glucose 1-Dehydrogenase, Glucose Dehydrogenases/biosynthesis/metabolism, Hydrogen-Ion Concentration, Klebsiella pneumoniae/enzymology/*metabolism, Oxidation-Reduction | Metabolism |
Metabolism | 2663635 | Nitrogen-limited behaviour of micro-organisms growing in the presence of large concentrations of ammonium ions. | Buurman ET, Teixeira de Mattos MJ, Neijssel OM | FEMS Microbiol Lett | 10.1016/0378-1097(89)90043-8 | 1989 | Ammonia/*metabolism, Biological Transport, Active, Glucose/metabolism, Glutamate Dehydrogenase/metabolism, Glutamate Synthase/metabolism, Hydrogen-Ion Concentration, Klebsiella pneumoniae/*metabolism, Nitrogen/*metabolism | Enzymology |
Pathogenicity | 3015853 | Potential prodrugs of 6-acetylmethylenepenicillanic acid (Ro 15-1903). | Adam S, Then R, Angehrn P | J Antibiot (Tokyo) | 10.7164/antibiotics.39.833 | 1986 | Ampicillin/pharmacology, Bacteria/drug effects, Drug Synergism, Penicillanic Acid/*chemical synthesis, *beta-Lactamase Inhibitors | |
Cultivation | 3309157 | Establishment of the steady state in glucose-limited chemostat cultures of Klebsiella pneumoniae. | Rutgers M, Teixeira de Mattos MJ, Postma PW, Van Dam K | J Gen Microbiol | 10.1099/00221287-133-2-445 | 1987 | Culture Media, Glucose/*metabolism, Kinetics, Klebsiella pneumoniae/*growth & development | Enzymology |
Metabolism | 6284704 | DHA system mediating aerobic and anaerobic dissimilation of glycerol in Klebsiella pneumoniae NCIB 418. | Forage RG, Lin EC | J Bacteriol | 10.1128/jb.151.2.591-599.1982 | 1982 | Aerobiosis, Anaerobiosis, Cyclic AMP/pharmacology, Enzyme Repression, Glycerol/*metabolism, Glycerophosphates/metabolism, Klebsiella pneumoniae/genetics/*metabolism, Mutation, Phosphotransferases/*metabolism, *Phosphotransferases (Alcohol Group Acceptor) | |
Pathogenicity | 7003318 | Cobalt and nickel sensitivity and tolerance in Klebsiella pneumoniae. | Ainsworth MA, Tompsett CP, Dean AC | Microbios | 1980 | Cadmium/pharmacology, Cobalt/*pharmacology, Dose-Response Relationship, Drug, Drug Synergism, Klebsiella pneumoniae/*drug effects/growth & development, Nickel/*pharmacology, Zinc/pharmacology | ||
Metabolism | 7755965 | Comparison of the energetic efficiencies of hydrogen and oxychemicals formation in Klebsiella pneumoniae and Clostridium butyricum during anaerobic growth on glycerol. | Solomon BO, Zeng AP, Biebl H, Schlieker H, Posten C, Deckwer WD | J Biotechnol | 10.1016/0168-1656(94)00148-6 | 1995 | Clostridium/growth & development/*metabolism, Culture Media, Electrons, Energy Metabolism, Glycerol/*metabolism, Hydrogen/*metabolism, Klebsiella pneumoniae/growth & development/*metabolism | Cultivation |
Metabolism | 7952195 | The physiological function of periplasmic glucose oxidation in phosphate-limited chemostat cultures of Klebsiella pneumoniae NCTC 418. | Buurman ET, ten Voorde GJ, Teixeira de Mattos MJ | Microbiology (Reading) | 10.1099/13500872-140-9-2451 | 1994 | Adenosine Triphosphate/metabolism, Carbohydrate Dehydrogenases/metabolism, Carbon Dioxide/metabolism, Culture Media, Enzyme Activation, Glucose/*metabolism, Glucose 1-Dehydrogenase, Glucose Dehydrogenases/metabolism, Glyceraldehyde-3-Phosphate Dehydrogenases/metabolism, Kinetics, Klebsiella pneumoniae/*metabolism, Oxidation-Reduction, Oxygen Consumption, Phosphates/metabolism | Enzymology |
Metabolism | 8387264 | Gluconate metabolism of Klebsiella pneumoniae NCTC 418 grown in chemostat culture. | Simons JA, Teixeira de Mattos MJ, Neijssel OM | Arch Microbiol | 10.1007/BF00290922 | 1993 | Aerobiosis, Anaerobiosis, Carbohydrate Dehydrogenases/*metabolism, Gluconates/*metabolism, Hydrogen-Ion Concentration, Klebsiella pneumoniae/enzymology/*metabolism, Phosphotransferases/*metabolism, *Phosphotransferases (Alcohol Group Acceptor) | Enzymology |
Pathogenicity | 8879559 | Synthesis and biological evaluation of an electronically activated isooxacephem. | Hakimelahi GH, Tsay SC, Tso HH, Ramezani Z, Hwu JR | Bioorg Med Chem | 10.1016/0968-0896(96)00131-9 | 1996 | Anti-Bacterial Agents/*chemistry, Cephalosporins/*chemistry, Microbial Sensitivity Tests, Pseudomonas aeruginosa/drug effects, Staphylococcus aureus/drug effects | |
Metabolism | 12908084 | Microbial fed-batch production of 1,3-propanediol by Klebsiella pneumoniae under micro-aerobic conditions. | Chen X, Zhang DJ, Qi WT, Gao SJ, Xiu ZL, Xu P | Appl Microbiol Biotechnol | 10.1007/s00253-003-1369-5 | 2003 | Aerobiosis, Anaerobiosis, Bioreactors, Biotechnology/methods, Culture Media, Fermentation/drug effects, Glycerol/*metabolism, Klebsiella pneumoniae/*growth & development/*metabolism, Propylene Glycols/*metabolism | Biotechnology |
Pathogenicity | 12956062 | Application of the Barton photochemical reaction in the synthesis of 1-dethia-3-aza-1-carba-2-oxacephem: a novel agent against resistant pathogenic microorganisms. | Hakimelahi GH, Li PC, Moosavi-Movahedi AA, Chamani J, Khodarahmi GA, Ly TW, Valiyev F, Leong MK, Hakimelahi S, Shia KS, Chao I | Org Biomol Chem | 10.1039/b304167k | 2003 | Anti-Infective Agents/*chemical synthesis/chemistry/*pharmacology, Cell Division/drug effects, Cells, Cultured, Cephalosporins/*chemical synthesis/chemistry/*pharmacology, Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/chemistry, Drug Resistance, Bacterial, Enzyme Inhibitors/chemistry/pharmacology, Escherichia coli/*drug effects/enzymology/genetics, Humans, Isomerism, Klebsiella pneumoniae/drug effects/genetics, Methicillin/pharmacology, Microbial Sensitivity Tests, Models, Molecular, Pseudomonas aeruginosa/*drug effects/enzymology/genetics, Staphylococcus aureus/*drug effects/enzymology/genetics, beta-Lactamase Inhibitors, beta-Lactams/chemistry/pharmacology | Enzymology |
Pathogenicity | 15804533 | Carbapenem-based prodrugs. Design, synthesis, and biological evaluation of carbapenems. | Hakimelahi GH, Moosavi-Movahedi AA, Saboury AA, Osetrov V, Khodarahmi GA, Shia KS | Eur J Med Chem | 10.1016/j.ejmech.2004.11.002 | 2005 | Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Carbapenems/*chemical synthesis/chemistry/*pharmacology, *Drug Design, Enzyme Inhibitors/chemical synthesis/chemistry/pharmacology, Molecular Structure, Prodrugs/*chemical synthesis/chemistry/*pharmacology, beta-Lactamase Inhibitors, beta-Lactamases/metabolism | Metabolism |
Enzymology | 16697481 | Discovery and investigation of a new, second triose phosphate isomerase in Klebsiella pneumoniae. | Zheng P, Sun J, van den Heuvel J, Zeng AP | J Biotechnol | 10.1016/j.jbiotec.2006.03.034 | 2006 | 3' Flanking Region, 5' Flanking Region, Amino Acid Sequence, Cloning, Molecular, Computational Biology, Genes, Bacterial/physiology, Klebsiella pneumoniae/*enzymology/*genetics, Models, Genetic, Molecular Sequence Data, Sequence Homology, Amino Acid, Triose-Phosphate Isomerase/*genetics/*isolation & purification/physiology | Genetics |
Metabolism | 17260330 | Optimization of bio-hydrogen production from biodiesel wastes by Klebsiella pneumoniae. | Liu F, Fang B | Biotechnol J | 10.1002/biot.200600102 | 2007 | Bioreactors/microbiology, Carbon Dioxide/metabolism, Chromatography, Gas, Chromatography, High Pressure Liquid, Fermentation, Glycerol/*metabolism, Hydrogen/*metabolism, Hydrogen-Ion Concentration, Industrial Microbiology/methods, Klebsiella pneumoniae/*metabolism, Models, Biological, Propylene Glycols/metabolism, Temperature | Biotechnology |
18475938 | C-3 Substituted Lawsonemonoximates of Holmium(III): Synthesis, Characterization, and Antimicrobial Activity. | Jagtap SB, Joshi SG, Litake GM, Ghole VS, Kulkarni BA | Met Based Drugs | 10.1155/MBD.2000.147 | 2000 | |||
Metabolism | 20601262 | 1,3-Propanediol production from crude glycerol from Jatropha biodiesel process. | Hiremath A, Kannabiran M, Rangaswamy V | N Biotechnol | 10.1016/j.nbt.2010.06.006 | 2010 | *Biofuels, Biotechnology/*methods, Fermentation, Glucose/metabolism, Glycerol/*metabolism, Jatropha/*metabolism, Klebsiella pneumoniae/metabolism, Polyethylene Terephthalates/metabolism, Polymerization, Propylene Glycols/isolation & purification/*metabolism | Biotechnology |
Metabolism | 21336929 | Development of recombinant Klebsiella pneumoniae dhaT strain for the co-production of 3-hydroxypropionic acid and 1,3-propanediol from glycerol. | Ashok S, Raj SM, Rathnasingh C, Park S | Appl Microbiol Biotechnol | 10.1007/s00253-011-3148-z | 2011 | Alcohol Dehydrogenase/*genetics/metabolism, Aldehyde Oxidoreductases/genetics/metabolism, Bacterial Proteins/*genetics/metabolism, *Gene Deletion, Genetic Engineering, Glycerol/*metabolism, Klebsiella pneumoniae/enzymology/genetics/*metabolism, Lactic Acid/*analogs & derivatives/metabolism, Propylene Glycols/*metabolism | Enzymology |
Metabolism | 22307808 | Fermentation and evaluation of Klebsiella pneumoniae and K. oxytoca on the production of 2,3-butanediol. | Cho JH, Rathnasingh C, Song H, Chung BW, Lee HJ, Seung D | Bioprocess Biosyst Eng | 10.1007/s00449-012-0691-7 | 2012 | Butylene Glycols/*metabolism, *Fermentation, Klebsiella oxytoca/*metabolism, Klebsiella pneumoniae/*metabolism, Microscopy, Electron, Scanning | Biotechnology |
Metabolism | 23022570 | Effect of puuC overexpression and nitrate addition on glycerol metabolism and anaerobic 3-hydroxypropionic acid production in recombinant Klebsiella pneumoniae DeltaglpKDeltadhaT. | Ashok S, Mohan Raj S, Ko Y, Sankaranarayanan M, Zhou S, Kumar V, Park S | Metab Eng | 10.1016/j.ymben.2012.09.004 | 2012 | Aldehyde Oxidoreductases/genetics/*metabolism, Anaerobiosis/physiology, Genetic Enhancement/*methods, Glycerol/*metabolism, Klebsiella pneumoniae/classification/*physiology, Lactic Acid/*analogs & derivatives/biosynthesis, Nitrates/*metabolism, Recombination, Genetic/*genetics, Species Specificity, Up-Regulation | Phylogeny |
Genetics | 23405357 | Genome Sequence of Klebsiella pneumoniae Ecl8, a Reference Strain for Targeted Genetic Manipulation. | Fookes M, Yu J, De Majumdar S, Thomson N, Schneiders T | Genome Announc | 10.1128/genomeA.00027-12 | 2013 | ||
Metabolism | 24002450 | Characterization and cofactor binding mechanism of a novel NAD(P)H-dependent aldehyde reductase from Klebsiella pneumoniae DSM2026. | Ma CW, Zhang L, Dai JY, Xiu ZL | J Microbiol Biotechnol | 10.4014/jmb.1307.07015 | 2013 | Alcohol Oxidoreductases/chemistry/genetics/*metabolism, Cloning, Molecular, Coenzymes/chemistry/*metabolism, Glyceraldehyde/analogs & derivatives/metabolism, Klebsiella pneumoniae/*enzymology/genetics, Models, Molecular, Molecular Dynamics Simulation, NAD/chemistry/*metabolism, NADP/chemistry/*metabolism, Propane/metabolism, Propylene Glycols/*metabolism, Protein Binding, Static Electricity, Substrate Specificity | Enzymology |
Reference
@id | authors | catalogue | doi/url | title |
---|---|---|---|---|
959 | Curators of the DSMZ | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 2026) | https://www.dsmz.de/collection/catalogue/details/culture/DSM-2026 | |
20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M. | 10.1099/ijsem.0.004332 | List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ | |
35132 | Curators of the CIP | https://brclims.pasteur.fr/brcWeb/souche/detail/1/15563 | ||
66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | https://diaspora-project.de/progress.html#genomes | Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | |
68368 | Automatically annotated from API 20E | |||
68371 | Automatically annotated from API 50CH acid | |||
68382 | Automatically annotated from API zym | |||
69480 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | https://diaspora-project.de/progress.html#genomes | Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | |
69481 | Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch | 10.21203/rs.3.rs-2527258/v1 | Predictions based on the model GenomeNet Sporulation v. 1 | |
74444 | Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J. | 10.60712/SI-ID45585.1 | StrainInfo: A central database for resolving microbial strain identifiers | |
121883 | Curators of the CIP | Collection of Institut Pasteur (CIP 103733) | https://catalogue-crbip.pasteur.fr/fiche_catalogue.xhtml?crbip=CIP%20103733 |