Strain identifier
BacDive ID: 2631
Type strain: 
Species: Clostridium perfringens
Strain Designation: S107
Strain history: ATCC 13124 <-- NCTC 8237 ("Clostridium welchii") <-- Wellcome Lab.; CN 1491.
NCBI tax ID(s): 195103 (strain), 1502 (species)
version 8.1 (current version)
General
@ref: 428
BacDive-ID: 2631
DSM-Number: 756
keywords: genome sequence, 16S sequence, Bacteria, anaerobe, spore-forming, mesophilic, Gram-positive, toxin production, human pathogen
description: Clostridium perfringens S107 is an anaerobe, spore-forming, mesophilic human pathogen that produces toxins and was isolated from bovine.
NCBI tax id
| NCBI tax id | Matching level |
|---|---|
| 195103 | strain |
| 1502 | species |
strain history
| @ref | history |
|---|---|
| 428 | <- NCIB <- NCTC <- D. McClean <- H. Schmidt, Marburg, Germany, S107 ("Clostridium welchii") |
| 67770 | ATCC 13124 <-- NCTC 8237 ("Clostridium welchii") <-- Wellcome Lab.; CN 1491. |
doi: 10.13145/bacdive2631.20230509.8.1
Name and taxonomic classification
LPSN
- @ref: 20215
- description: domain/bacteria
- keyword: phylum/bacillota
- domain: Bacteria
- phylum: Bacillota
- class: Clostridia
- order: Eubacteriales
- family: Clostridiaceae
- genus: Clostridium
- species: Clostridium perfringens
- full scientific name: Clostridium perfringens (Veillon and Zuber 1898) Hauduroy et al. 1937 (Approved Lists 1980)
synonyms
- @ref: 20215
- synonym: Bacillus perfringens
@ref: 428
domain: Bacteria
phylum: Firmicutes
class: Clostridia
order: Clostridiales
family: Clostridiaceae
genus: Clostridium
species: Clostridium perfringens
full scientific name: Clostridium perfringens (Veillon and Zuber 1898) Hauduroy et al. 1937
strain designation: S107
type strain: yes
Morphology
cell morphology
- @ref: 69480
- gram stain: positive
- confidence: 100
Culture and growth conditions
culture medium
| @ref | name | growth | link | composition |
|---|---|---|---|---|
| 428 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | yes | https://mediadive.dsmz.de/medium/693 | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base |
| 428 | FASTIDIOUS ANAEROBE BROTH (DSMZ Medium 1203a) | yes | https://mediadive.dsmz.de/medium/1203a | Name: FASTIDIOUS ANAEROBE BROTH (DSMZ Medium 1203a) Composition: Fastidious Anaerobe Basal Broth 35.4 g/l Distilled water |
| 428 | CHOPPED MEAT MEDIUM WITH CARBOHYDRATES (DSMZ Medium 110) | yes | https://mediadive.dsmz.de/medium/110 | Name: CHOPPED MEAT MEDIUM WITH CARBOHYDRATES (DSMZ Medium 110) Composition: Ground beef 500.0 g/l Casitone 30.0 g/l Agar 15.0 g/l K2HPO4 5.0 g/l Yeast extract 5.0 g/l D-Glucose 4.0 g/l Starch 1.0 g/l Maltose 1.0 g/l Cellobiose 1.0 g/l L-Cysteine HCl 0.5 g/l Ethanol 0.19 g/l Vitamin K3 0.05 g/l Hemin 0.005 g/l Sodium resazurin 0.0005 g/l Vitamin K1 NaOH Distilled water |
| 42056 | MEDIUM 20 - for Anaerobic bacteria | yes | Agar (15.000 g);Glucose (5.000 g);Yeast extract (20.000 g);Tryptone (30.000 g);Cysteine hydrochloride (0.500 g);distilled water (1000.000 ml);Hemin solution -M00149 (25.000 ml) |
culture temp
| @ref | growth | type | temperature | range |
|---|---|---|---|---|
| 428 | positive | growth | 37 | mesophilic |
| 42056 | positive | growth | 37 | mesophilic |
| 44424 | positive | growth | 37 | mesophilic |
| 67770 | positive | growth | 37 | mesophilic |
Physiology and metabolism
oxygen tolerance
| @ref | oxygen tolerance | confidence |
|---|---|---|
| 428 | anaerobe | |
| 44424 | anaerobe | |
| 69480 | anaerobe | 98.649 |
spore formation
| @ref | spore formation | confidence |
|---|---|---|
| 69481 | yes | 100 |
| 69480 | yes | 99.999 |
compound production
| @ref | compound |
|---|---|
| 428 | haemolysins |
| 428 | lecithinase |
| 428 | lethal toxins |
| 428 | phospholipase C |
| 67770 | haemolysins |
| 67770 | lethal toxins |
metabolite utilization
| @ref | Chebi-ID | metabolite | utilization activity | kind of utilization tested |
|---|---|---|---|---|
| 68367 | 27082 | trehalose | + | builds acid from |
| 68367 | 62345 | L-rhamnose | - | builds acid from |
| 68367 | 30911 | sorbitol | - | builds acid from |
| 68367 | 16634 | raffinose | - | builds acid from |
| 68367 | 6731 | melezitose | - | builds acid from |
| 68367 | 16024 | D-mannose | + | builds acid from |
| 68367 | 17057 | cellobiose | - | builds acid from |
| 68367 | 4853 | esculin | + | hydrolysis |
| 68367 | 5291 | gelatin | + | hydrolysis |
| 68367 | 30849 | L-arabinose | - | builds acid from |
| 68367 | 65327 | D-xylose | - | builds acid from |
| 68367 | 17814 | salicin | - | builds acid from |
| 68367 | 17306 | maltose | + | builds acid from |
| 68367 | 17992 | sucrose | + | builds acid from |
| 68367 | 17716 | lactose | + | builds acid from |
| 68367 | 17634 | D-glucose | + | builds acid from |
| 68367 | 16199 | urea | - | hydrolysis |
| 68367 | 27897 | tryptophan | - | energy source |
| 68380 | 16199 | urea | - | hydrolysis |
| 68380 | 29016 | arginine | + | hydrolysis |
| 68380 | 16024 | D-mannose | + | fermentation |
| 68380 | 16634 | raffinose | + | fermentation |
| 68380 | 29985 | L-glutamate | - | degradation |
| 68380 | 17632 | nitrate | + | reduction |
| 68380 | 27897 | tryptophan | - | energy source |
metabolite production
| @ref | Chebi-ID | metabolite | production |
|---|---|---|---|
| 68367 | 35581 | indole | no |
| 68380 | 35581 | indole | no |
metabolite tests
| @ref | Chebi-ID | metabolite | indole test |
|---|---|---|---|
| 68380 | 35581 | indole | - |
| 68367 | 35581 | indole | - |
enzymes
| @ref | value | activity | ec |
|---|---|---|---|
| 68380 | serine arylamidase | - | |
| 68380 | glutamyl-glutamate arylamidase | - | |
| 68380 | histidine arylamidase | - | |
| 68380 | glycin arylamidase | - | |
| 68380 | alanine arylamidase | - | 3.4.11.2 |
| 68380 | tyrosine arylamidase | - | |
| 68380 | pyrrolidonyl arylamidase | + | 3.4.19.3 |
| 68380 | leucine arylamidase | - | 3.4.11.1 |
| 68380 | phenylalanine arylamidase | - | |
| 68380 | leucyl glycin arylamidase | - | 3.4.11.1 |
| 68380 | proline-arylamidase | - | 3.4.11.5 |
| 68380 | alkaline phosphatase | + | 3.1.3.1 |
| 68380 | tryptophan deaminase | - | 4.1.99.1 |
| 68380 | alpha-fucosidase | + | 3.2.1.51 |
| 68380 | glutamate decarboxylase | - | 4.1.1.15 |
| 68380 | N-acetyl-beta-glucosaminidase | + | 3.2.1.52 |
| 68380 | beta-glucuronidase | - | 3.2.1.31 |
| 68380 | alpha-arabinosidase | - | 3.2.1.55 |
| 68380 | alpha-glucosidase | + | 3.2.1.20 |
| 68380 | beta-galactosidase | + | 3.2.1.23 |
| 68380 | alpha-galactosidase | + | 3.2.1.22 |
| 68380 | arginine dihydrolase | + | 3.5.3.6 |
| 68380 | urease | - | 3.5.1.5 |
| 67770 | phospholipase C | 3.1.4.11 | |
| 68367 | beta-glucosidase | + | 3.2.1.21 |
| 68367 | gelatinase | + | |
| 68367 | urease | - | 3.5.1.5 |
API 20A
| @ref | IND | URE | GLU | MAN | LAC | SAC | MAL | SAL | XYL | ARA | GEL | ESC | GLY | CEL | MNE | MLZ | RAF | SOR | RHA | TRE |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 428 | - | - | + | - | + | + | + | - | - | - | + | + | - | - | + | - | - | - | - | + |
| 428 | - | - | + | +/- | + | + | + | - | - | - | + | + | + | - | + | - | - | - | - | + |
API rID32A
| @ref | URE | ADH Arg | alpha GAL | beta GAL | beta GP | alpha GLU | beta GLU | alpha ARA | beta GUR | beta NAG | MNE | RAF | GDC | alpha FUC | NIT | IND | PAL | ArgA | ProA | LGA | PheA | LeuA | PyrA | TyrA | AlaA | GlyA | HisA | GGA | SerA |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 428 | - | + | + | + | - | + | - | - | - | + | + | + | - | + | + | - | + | - | - | - | - | - | + | - | - | - | - | - | - |
| 428 | - | + | + | + | + | + | + | - | - | + | + | + | - | + | + | - | + | - | - | - | - | - | + | - | - | - | - | - | - |
| 428 | - | + | + | + | - | + | - | - | - | + | + | + | - | + | + | - | + | + | - | - | - | - | + | - | - | - | - | - | - |
Isolation, sampling and environmental information
isolation
| @ref | sample type |
|---|---|
| 428 | bovine |
| 44424 | Bovine |
| 67770 | Bovine |
isolation source categories
- Cat1: #Host
- Cat2: #Mammals
- Cat3: #Bovinae (Cow, Cattle)
taxonmaps
- @ref: 69479
- File name: preview.99_335.png
- url: https://microbeatlas.org/index.html?action=taxon&taxon_id=90_34;96_235;97_257;98_286;99_335&stattab=map
- Last taxonomy: Clostridium perfringens subclade
- 16S sequence: AB573713
- Sequence Identity:
- Total samples: 88326
- soil counts: 3063
- aquatic counts: 8762
- animal counts: 75654
- plant counts: 847
Safety information
risk assessment
- @ref: 428
- pathogenicity human: yes
- pathogenicity animal: yes
- biosafety level: 2
- biosafety level comment: Risk group (German classification)
Sequence information
16S sequences
| @ref | description | accession | length | database | NCBI tax ID |
|---|---|---|---|---|---|
| 20218 | Clostridium perfringens gene for 16S rRNA, partial sequence, strain: ATCC 13124 | AB075767 | 1460 | ena | 195103 |
| 20218 | Clostridium perfringens partial 16S rRNA gene, strain ATCC 13124 | FM207095 | 390 | ena | 195103 |
| 20218 | Clostridium perfringens strain DSM 756 16S ribosomal RNA gene, partial sequence | HQ012013 | 933 | ena | 1502 |
| 20218 | Clostridium perfringens 16S ribosomal RNA | M59103 | 1462 | ena | 1502 |
| 20218 | {16S/23S ribosomal DNA spacer region} [Clostridium perfringens, ATCC 13124, Genomic, 239 nt] | S51964 | 239 | ena | 1502 |
| 67770 | Clostridium perfringens gene for 16S ribosomal RNA, partial sequence, strain: JCM 1290 | AB573713 | 1474 | ena | 1502 |
Genome sequences
| @ref | description | accession | assembly level | database | NCBI tax ID |
|---|---|---|---|---|---|
| 66792 | Clostridium perfringens ATCC 13124 | GCA_000013285 | complete | ncbi | 195103 |
| 66792 | Clostridium perfringens ATCC 13124 | 195103.10 | complete | patric | 195103 |
| 66792 | Clostridium perfringens strain FDAARGOS_903 | 1502.1789 | complete | patric | 1502 |
| 66792 | Clostridium perfringens ATCC 13124 | 637000077 | complete | img | 195103 |
GC content
| @ref | GC-content | method |
|---|---|---|
| 428 | 24.0 | |
| 67770 | 24 | thermal denaturation, midpoint method (Tm) |
Genome-based predictions
predictions
| trait | prediction | confidence | training_data |
|---|---|---|---|
| spore-forming | yes | 100 | no |
| motile | no | 80.249 | no |
| flagellated | no | 90.214 | no |
| gram-positive | yes | 92.714 | no |
| anaerobic | yes | 97.401 | yes |
| halophile | no | 75.27 | no |
| spore-forming | yes | 90.952 | no |
| thermophile | no | 99.342 | no |
| glucose-util | yes | 89.989 | no |
| aerobic | no | 96.247 | no |
| glucose-ferment | yes | 76.721 | no |
External links
@ref: 428
culture collection no.: DSM 756, ATCC 13124, ATCC 19408, NCIB 6125, NCTC 6125, NCTC 8237, WDCM 00007, CCUG 1795, CIP 103409, JCM 1290, BCRC 10913, CCM 4435, CECT 376, KCTC 3269, LMG 11264, NCIMB 6125
straininfo link
- @ref: 72162
- straininfo: 289341
literature
| topic | Pubmed-ID | title | authors | journal | DOI | year | mesh | topic2 |
|---|---|---|---|---|---|---|---|---|
| Pathogenicity | 10344 | Production of phospholipase C (alpha-toxin), haemolysins and lethal toxins by Clostridium perfringens types A to D. | Mollby R, Holme T, Nord CE, Smyth CJ, Wadstrom T | J Gen Microbiol | 10.1099/00221287-96-1-137 | 1976 | Abdominal Injuries/microbiology, Clostridium Infections/microbiology, Clostridium perfringens/classification/growth & development/*metabolism, Feces/microbiology, Gas Gangrene/microbiology, Hemolysin Proteins/*biosynthesis, Humans, Hydrogen-Ion Concentration, Phospholipases/*biosynthesis, Serotyping, Species Specificity, Toxins, Biological/*biosynthesis | Phylogeny |
| Cultivation | 518079 | Collaborative evaluation of a proposed reference dilution method of susceptibility testing of anaerobic bacteria. | Sutter VL, Barry AL, Wilkins TD, Zabransky RJ | Antimicrob Agents Chemother | 10.1128/AAC.16.4.495 | 1979 | Anaerobiosis, Anti-Bacterial Agents/*pharmacology, Bacteria/*drug effects, Culture Media, Evaluation Studies as Topic, Microbial Sensitivity Tests/*methods | Pathogenicity |
| Enzymology | 1665065 | Collagenase of Clostridium perfringens type A: degradation of human complement component C1q. | Wolf U, Bauer D, Traub WH | Zentralbl Bakteriol | 10.1016/s0934-8840(11)80215-x | 1991 | Blotting, Western, Clostridium perfringens/*enzymology, Complement C1q/*metabolism, Electrophoresis, Polyacrylamide Gel, Humans, Isoelectric Point, Microbial Collagenase/chemistry/isolation & purification/*metabolism, Molecular Weight | Metabolism |
| Pathogenicity | 2280013 | Quality control criteria for testing the susceptibility of anaerobic bacteria to meropenem. | Zabransky RJ, Bayola-Mueller L, Jenkins SG, Pitkin DR, Schreckenberger PC, Celig DM, Spiegel CA | J Clin Microbiol | 10.1128/jcm.28.12.2804-2805.1990 | 1990 | Bacteria, Anaerobic/*drug effects, Meropenem, Microbial Sensitivity Tests/methods/*standards, Quality Control, Reference Values, Thienamycins/*pharmacology | |
| Pathogenicity | 2643621 | Quality control guidelines for testing cefotetan in the reference agar dilution procedure for susceptibility testing of anaerobic bacteria. | Zabransky RJ, Bobey DG, Barry AL, Allen SD, Fuchs PC, Gerlach EH, Thornsberry C, Sheikh W, Jones RN | J Clin Microbiol | 10.1128/jcm.27.1.190-191.1989 | 1989 | Bacteria, Anaerobic/*drug effects, Cefotetan/*pharmacology, Microbial Sensitivity Tests/*standards, Multicenter Studies as Topic, Quality Control, Reference Values | |
| Pathogenicity | 2882731 | Effect of antibiotics on toxin production and viability of Clostridium perfringens. | Stevens DL, Maier KA, Mitten JE | Antimicrob Agents Chemother | 10.1128/AAC.31.2.213 | 1987 | Anti-Bacterial Agents/*pharmacology, Bacterial Toxins/*biosynthesis, *Calcium-Binding Proteins, Cefoxitin/pharmacology, Chloramphenicol/pharmacology, Clindamycin/pharmacology, Clostridium perfringens/*drug effects/growth & development/metabolism, Kinetics, Metronidazole/pharmacology, Microbial Sensitivity Tests, Penicillin G/pharmacology, Rifampin/pharmacology, Tetracycline/pharmacology, *Type C Phospholipases | Enzymology |
| Cultivation | 2886986 | Evaluation of some commercial media for the cultivation and enumeration of Clostridium perfringens from the chick intestine. | Dafwang II, Ricke SC, Schaefer DM, Brotz PG, Sunde ML, Pringle DJ | Poult Sci | 10.3382/ps.0660652 | 1987 | Animals, Chickens/*microbiology, Clostridium perfringens/growth & development/*isolation & purification, Culture Media, Intestines/*microbiology | Enzymology |
| Cultivation | 2892327 | Growth curves of Clostridium perfringens in Schaedler and brain heart infusion broths. | Traub WH, Spohr M, Bauer D | Zentralbl Bakteriol Mikrobiol Hyg A | 10.1016/s0176-6724(87)80035-4 | 1987 | Animals, Clostridium perfringens/*growth & development/pathogenicity, Culture Media, Humans, Mice, Virulence | Pathogenicity |
| Enzymology | 2903127 | Cloning and expression in Escherichia coli of the perfringolysin O (theta-toxin) gene from Clostridium perfringens and characterization of the gene product. | Tweten RK | Infect Immun | 10.1128/iai.56.12.3228-3234.1988 | 1988 | Amino Acid Sequence, Bacterial Toxins/*genetics/metabolism, Cloning, Molecular, Clostridium perfringens/*genetics, Escherichia coli/genetics/metabolism, Genes, Bacterial, Hemolysin Proteins, Hemolysis, Molecular Sequence Data, Molecular Weight, Peptide Mapping, Recombinant Proteins/genetics, Restriction Mapping | Metabolism |
| Enzymology | 3492177 | Inactivation of cefoxitin and moxalactam by Bacteroides bivius beta-lactamase. | Malouin F, Fijalkowski C, Lamothe F, Lacroix JM | Antimicrob Agents Chemother | 10.1128/AAC.30.5.749 | 1986 | Bacteroides/*enzymology, Biological Assay, Cefoxitin/*antagonists & inhibitors/pharmacology, Hydrolysis, Microbial Sensitivity Tests, Moxalactam/*antagonists & inhibitors/pharmacology, Spectrophotometry, Ultraviolet, beta-Lactamases/*pharmacology | |
| Pathogenicity | 3888103 | Establishment of MICs of moxalactam for control and reference anaerobic organisms in agar dilution and microdilution techniques. | Sutter VL, Emmerman J, Randall E, Zabransky RJ, Birk RJ | Antimicrob Agents Chemother | 10.1128/AAC.27.3.424 | 1985 | Agar, Bacteria, Anaerobic/*drug effects, Microbial Sensitivity Tests, Microbiological Techniques, Moxalactam/*pharmacology | |
| Pathogenicity | 3972999 | Evaluation of broth microdilution susceptibility results for anaerobic organisms by use of a rapid direct colony inoculum. | Mangels JI, Lindberg LH | J Clin Microbiol | 10.1128/jcm.21.2.269-272.1985 | 1985 | Bacteria, Anaerobic/*drug effects, Humans, Microbial Sensitivity Tests/*methods, Quality Control, Tetracycline/pharmacology | |
| Pathogenicity | 6222065 | Establishment of minimum inhibitory concentrations of cefoperazone for control and reference anaerobic organisms. | Zabransky RJ, Randall E, Sutter VL, Birk RJ, Westenfelder G, Emmerman J, Ghoneim AT | J Clin Microbiol | 10.1128/jcm.17.4.711-714.1983 | 1983 | Anaerobiosis, Bacteria/*drug effects, Cefoperazone, Cephalosporins/*pharmacology, Microbial Sensitivity Tests | |
| Phylogeny | 7603469 | Synthesis and evaluation of a non-radioactive gene probe for the detection of C.perfringens alpha toxin. | Schlapp T, Blaha I, Bauerfeind R, Wieler LH, Schoepe H, Weiss R, Baljer G | Mol Cell Probes | 10.1016/s0890-8508(95)80034-4 | 1995 | Bacillus cereus/classification, Bacterial Toxins/*analysis/genetics, Base Sequence, *Calcium-Binding Proteins, Chromosomes, Bacterial, Clostridium/classification/genetics, Clostridium perfringens/classification/genetics/*isolation & purification, DNA Primers/*chemical synthesis, Genes, Bacterial, Humans, Listeria monocytogenes/classification, Molecular Sequence Data, Nucleic Acid Hybridization, Staphylococcus aureus/classification, *Type C Phospholipases | Pathogenicity |
| Metabolism | 7927785 | Role of alpha-toxin in Clostridium perfringens infection determined by using recombinants of C. perfringens and Bacillus subtilis. | Ninomiya M, Matsushita O, Minami J, Sakamoto H, Nakano M, Okabe A | Infect Immun | 10.1128/iai.62.11.5032-5039.1994 | 1994 | Animals, Bacillus subtilis, Bacterial Toxins/metabolism/*toxicity, *Calcium-Binding Proteins, Clostridium Infections/pathology/*physiopathology, Clostridium perfringens/*pathogenicity, Erythrocyte Count, Gas Gangrene/physiopathology, Hemolysin Proteins, Macrophages, Peritoneal/microbiology, Male, Mice, Platelet Count, Transformation, Genetic, Type C Phospholipases/metabolism | Pathogenicity |
| Phylogeny | 8123556 | 16S ribosomal DNA sequences of anaerobic cocci and proposal of Ruminococcus hansenii comb. nov. and Ruminococcus productus comb. nov. | Ezaki T, Li N, Hashimoto Y, Miura H, Yamamoto H | Int J Syst Bacteriol | 10.1099/00207713-44-1-130 | 1994 | Anaerobiosis, Base Sequence, DNA, Bacterial/*chemistry, DNA, Ribosomal/*chemistry, Molecular Sequence Data, Peptococcaceae/*classification/*genetics, RNA, Ribosomal, 16S/*genetics | Genetics |
| Genetics | 8423073 | Comparison of the alpha-toxin genes of Clostridium perfringens type A and C strains: evidence for extragenic regulation of transcription. | Katayama S, Matsushita O, Minami J, Mizobuchi S, Okabe A | Infect Immun | 10.1128/iai.61.2.457-463.1993 | 1993 | Amino Acid Sequence, Bacterial Toxins/*genetics, Base Sequence, *Calcium-Binding Proteins, Clostridium perfringens/enzymology/*genetics/pathogenicity, Escherichia coli/genetics, Gene Expression Regulation, *Genes, Bacterial, Molecular Sequence Data, RNA, Messenger/analysis, *Transcription, Genetic, Type C Phospholipases/*genetics | Pathogenicity |
| Enzymology | 8561916 | Diversity in the properties of two sialidase isoenzymes produced by Clostridium perfringens spp. | Roggentin P, Kleineidam RG, Schauer R | Biol Chem Hoppe Seyler | 10.1515/bchm3.1995.376.9.569 | 1995 | Chromatography, Gel, Clostridium perfringens/*enzymology, Electrophoresis, Polyacrylamide Gel, Hydrogen-Ion Concentration, Hydrolysis, Isoelectric Focusing, Isoenzymes/chemistry/*metabolism, Kinetics, Molecular Weight, Neuraminidase/chemistry/*metabolism, Recombinant Proteins/biosynthesis, Substrate Specificity, Temperature | Metabolism |
| Pathogenicity | 8581165 | Molecular variation between the alpha-toxins from the type strain (NCTC 8237) and clinical isolates of Clostridium perfringens associated with disease in man and animals. | Ginter A, Williamson ED, Dessy F, Coppe P, Bullifent H, Howells A, Titball RW | Microbiology (Reading) | 10.1099/13500872-142-1-191 | 1996 | Animals, Antibodies, Bacterial, Antibodies, Monoclonal, Antibody Specificity, Bacterial Toxins/*genetics/immunology/therapeutic use/toxicity, Bacterial Vaccines/*therapeutic use, Base Sequence, *Calcium-Binding Proteins, Cattle, Clostridium Infections/*prevention & control, Clostridium perfringens/genetics/*pathogenicity, Epitope Mapping, Female, *Genetic Variation, Humans, Intestinal Diseases/microbiology, Mice, Mice, Inbred BALB C, Molecular Sequence Data, Peptide Fragments/immunology, Sequence Analysis, DNA, Soft Tissue Infections/microbiology, Species Specificity, Type C Phospholipases/analysis, Vaccines, Synthetic/*therapeutic use, Virulence | Genetics |
| Metabolism | 8867610 | Characterization of a toxin-deficient Clostridium perfringens strain, KZ1340. | Shimizu T, Ohtani K, Ba-Thein W, Inui S, Nakamura S, Hayashi H | Microbiol Immunol | 10.1111/j.1348-0421.1996.tb03329.x | 1996 | Bacterial Toxins/*genetics/metabolism, *Calcium-Binding Proteins, Clostridium perfringens/*genetics/isolation & purification/metabolism, *Genes, Bacterial, Hemolysin Proteins, Microbial Collagenase/*genetics/metabolism, Plasmids, Transcription, Genetic, Transformation, Genetic, *Type C Phospholipases | Pathogenicity |
| Phylogeny | 8880985 | Improved isolation of Clostridium perfringens from foal faeces. | Netherwood T, Chanter N, Mumford JA | Res Vet Sci | 10.1016/s0034-5288(96)90090-9 | 1996 | Animals, Bacteriological Techniques, Clostridium Infections/diagnosis/*veterinary, Clostridium perfringens/*isolation & purification/physiology, Diarrhea/microbiology/*veterinary, Feces/microbiology, *Horse Diseases, Horses, Spores, Bacterial | Enzymology |
| Genetics | 9053381 | Collagenase gene (colA) is located in the 3'-flanking region of the perfringolysin O (pfoA) locus in Clostridium perfringens. | Ohtani K, Bando M, Swe T, Banu S, Oe M, Hayashi H, Shimizu T | FEMS Microbiol Lett | 10.1111/j.1574-6968.1997.tb10186.x | 1997 | Amino Acid Sequence, Bacterial Toxins/*genetics, Base Sequence, Chromosome Mapping, Clostridium perfringens/*enzymology/*genetics/pathogenicity, Collagenases/*genetics, DNA Primers/genetics, *Genes, Bacterial, Hemolysin Proteins, Molecular Sequence Data, Open Reading Frames, Virulence/genetics, beta-Galactosidase/genetics | Pathogenicity |
| Phylogeny | 9241799 | Evaluation of the synergistic haemolysis (CAMP-like) test in the identification of motile, mesophilic Aeromonas species. | Gubash SM | Zentralbl Bakteriol | 10.1016/s0934-8840(97)80073-4 | 1997 | Aeromonas/*classification/*isolation & purification, Aeromonas hydrophila/isolation & purification, Animals, Bacterial Toxins/immunology, *Bacterial Typing Techniques, Clostridium perfringens/immunology, Erythrocytes/immunology, Hemolysin Proteins, *Hemolysis, Sheep, *Sphingomyelin Phosphodiesterase, Staphylococcus aureus/immunology | Enzymology |
| Phylogeny | 10089527 | Crystallization and preliminary X-ray diffraction studies of alpha-toxin from two different strains (NCTC8237 and CER89L43) of Clostridium perfringens. | Basak AK, Howells A, Eaton JT, Moss DS, Naylor CE, Miller J, Titball RW | Acta Crystallogr D Biol Crystallogr | 10.1107/s0907444998005186 | 1998 | Bacterial Toxins/*chemistry/isolation & purification, *Calcium-Binding Proteins, Clostridium perfringens/*chemistry/classification, Crystallization, Crystallography, X-Ray, Escherichia coli, Protein Conformation, Recombinant Fusion Proteins/chemistry/isolation & purification, Species Specificity, Type C Phospholipases/*chemistry/isolation & purification | Enzymology |
| Enzymology | 10585141 | A Clostridium perfringens hem gene cluster contains a cysG(B) homologue that is involved in cobalamin biosynthesis. | Koyama M, Katayama S, Kaji M, Taniguchi Y, Matsushita O, Minami J, Morita S, Okabe A | Microbiol Immunol | 10.1111/j.1348-0421.1999.tb03355.x | 1999 | Base Sequence, Cloning, Molecular, Clostridium perfringens/*genetics/growth & development, DNA, Bacterial, *Genes, Bacterial, Methyltransferases/*genetics, Molecular Sequence Data, *Multigene Family, Mutagenesis, Open Reading Frames, Sequence Analysis, DNA, Sequence Homology, Amino Acid, Vitamin B 12/*biosynthesis | Genetics |
| Cultivation | 10716567 | An effective lacticin biopreservative in fresh pork sausage. | Scannell AG, Ross RP, Hill C, Arendt EK | J Food Prot | 10.4315/0362-028x-63.3.370 | 2000 | Animals, Bacterial Proteins/pharmacology, Bacteriocins/*pharmacology, Clostridium perfringens/growth & development, Culture Media, Food Handling, *Food Preservation, Food Preservatives/pharmacology, Lactococcus lactis/*metabolism, Listeria/growth & development, Meat Products/*microbiology, Salmonella/growth & development, Swine | Metabolism |
| Pathogenicity | 11297853 | Bactericidal properties of the chloroform fraction from rhizomes of Aristolochia paucinervis Pomel. | Gadhi CA, Hatier R, Mory F, Marchal L, Weber M, Benharref A, Jana M, Lozniewski A | J Ethnopharmacol | 10.1016/s0378-8741(01)00185-4 | 2001 | Anti-Bacterial Agents/*pharmacology, Chloroform/chemistry, Clostridium perfringens/*drug effects/ultrastructure, Enterococcus faecalis/*drug effects/ultrastructure, Magnoliopsida/*chemistry, Microbial Sensitivity Tests, Microscopy, Electron, Plant Extracts/*pharmacology | |
| Pathogenicity | 11938715 | In vitro effect of intracanal medicaments on strict anaerobes by means of the broth dilution method. | Rosa OP, Torres SA, Ferreira CM, Ferreira FB | Pesqui Odontol Bras | 10.1590/s1517-74912002000100006 | 2002 | Bacteria, Anaerobic/*drug effects, Indicator Dilution Techniques, Reproducibility of Results, Root Canal Therapy/*methods, Therapeutic Irrigation | |
| Pathogenicity | 12238802 | Activity of endodontic antibacterial agents against selected anaerobic bacteria. | Ferreira CM, da Silva Rosa OP, Torres SA, Ferreira FB, Bernardinelli N | Braz Dent J | 10.1590/s0103-64402002000200008 | 2002 | Bacteria, Anaerobic/*drug effects, Bacteroides fragilis/drug effects, Calcium Hydroxide/pharmacology, Camphor/pharmacology, Castor Oil/pharmacology, Chlorhexidine/*analogs & derivatives/pharmacology, Chlorophenols/pharmacology, Clostridium perfringens/drug effects, Culture Media, Detergents/pharmacology, Disinfectants/*pharmacology, Drug Combinations, Fusobacterium nucleatum/drug effects, Humans, Microbial Sensitivity Tests, Prevotella/drug effects, Root Canal Irrigants/*pharmacology, Spectrophotometry | Cultivation |
| Pathogenicity | 12650667 | Growth inhibition of intestinal bacteria and mutagenicity of 2-, 3-, 4-aminobiphenyls, benzidine, and biphenyl. | Chung KT, Adris P | Toxicol In Vitro | 10.1016/s0887-2333(02)00131-5 | 2003 | Aminobiphenyl Compounds/*toxicity, Benzidines/*toxicity, Biphenyl Compounds/*toxicity, Gram-Negative Bacteria/drug effects/growth & development, Gram-Positive Bacteria/drug effects/growth & development, Humans, Intestines/*microbiology, Mutagenicity Tests, Mutagens/*toxicity | |
| Cultivation | 15960756 | Susceptibility of Clostridium perfringens to C-C fatty acids. | Skrivanova E, Marounek M, Dlouha G, Kanka J | Lett Appl Microbiol | 10.1111/j.1472-765X.2005.01709.x | 2005 | Clostridium Infections/prevention & control/veterinary, Clostridium perfringens/*drug effects/growth & development/ultrastructure, Culture Media, Fatty Acids/administration & dosage/*pharmacology, Food Additives/administration & dosage, Glucose, Hydrogen-Ion Concentration, Lauric Acids/pharmacology, Microbial Sensitivity Tests, Microscopy, Electron, Transmission | Pathogenicity |
| Metabolism | 16085801 | Inhibition of Clostridium perfringens by a novel strain of Bacillus subtilis isolated from the gastrointestinal tracts of healthy chickens. | Teo AY, Tan HM | Appl Environ Microbiol | 10.1128/AEM.71.8.4185-4190.2005 | 2005 | Animals, *Antibiosis, Bacillus subtilis/classification/growth & development/*metabolism, Bacteriocins/chemistry/metabolism/*pharmacology, Chickens/*microbiology, Clostridium perfringens/*drug effects/growth & development, Culture Media, Gastrointestinal Tract/*microbiology, Hydrogen-Ion Concentration, Microbial Sensitivity Tests/methods, Temperature | Cultivation |
| Enzymology | 16511172 | Cloning, recombinant production, crystallization and preliminary X-ray diffraction studies of a family 84 glycoside hydrolase from Clostridium perfringens. | Ficko-Blean E, Boraston AB | Acta Crystallogr Sect F Struct Biol Cryst Commun | 10.1107/S1744309105024012 | 2005 | Catalysis, Cloning, Molecular, Clostridium perfringens/*enzymology/genetics, Crystallization, Glycoside Hydrolases/*chemistry/genetics, Recombinant Proteins/chemistry, X-Ray Diffraction | Biotechnology |
| Genetics | 16825665 | Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens. | Myers GS, Rasko DA, Cheung JK, Ravel J, Seshadri R, DeBoy RT, Ren Q, Varga J, Awad MM, Brinkac LM, Daugherty SC, Haft DH, Dodson RJ, Madupu R, Nelson WC, Rosovitz MJ, Sullivan SA, Khouri H, Dimitrov GI, Watkins KL, Mulligan S, Benton J, Radune D, Fisher DJ, Atkins HS, Hiscox T, Jost BH, Billington SJ, Songer JG, McClane BA, Titball RW, Rood JI, Melville SB, Paulsen IT | Genome Res | 10.1101/gr.5238106 | 2006 | Bacterial Toxins, Base Sequence, Clostridium perfringens/*genetics, DNA, Bacterial, *Genome, Bacterial, Molecular Sequence Data, Polymerase Chain Reaction | Pathogenicity |
| Metabolism | 17189979 | Detection of fibronectin-binding proteins in Clostridium perfringens. | Katayama S, Nozu N, Yokoyama M, Hitsumoto Y | Acta Med Okayama | 10.18926/AMO/30720 | 2006 | Carrier Proteins/*metabolism, Clostridium perfringens/*metabolism, Fibronectins/*metabolism, Humans, Protein Binding | Pathogenicity |
| Pathogenicity | 17981974 | Carbon catabolite repression of type IV pilus-dependent gliding motility in the anaerobic pathogen Clostridium perfringens. | Mendez M, Huang IH, Ohtani K, Grau R, Shimizu T, Sarker MR | J Bacteriol | 10.1128/JB.01407-07 | 2007 | Anaerobiosis, Animals, Bacterial Proteins/genetics, Chemotaxis/genetics/physiology, Cloning, Molecular, Clostridium perfringens/drug effects/genetics/*pathogenicity/*physiology, DNA Primers, DNA-Binding Proteins/genetics, Fimbriae, Bacterial/*physiology, Gene Deletion, Genetic Complementation Test, Glucose/pharmacology, Glucuronidase/genetics/metabolism, Humans, Plasmids, Repressor Proteins/genetics | Enzymology |
| Enzymology | 18183385 | Identification of galacto-N-biose phosphorylase from Clostridium perfringens ATCC13124. | Nakajima M, Nihira T, Nishimoto M, Kitaoka M | Appl Microbiol Biotechnol | 10.1007/s00253-007-1319-8 | 2008 | Bacterial Proteins/genetics/metabolism, Base Sequence, Bifidobacterium/enzymology, Cloning, Molecular, Clostridium perfringens/*enzymology/metabolism, Codon, Initiator/analysis, Enzyme Stability, Galactose/*metabolism, Humans, Kinetics, Phosphorylases/chemistry/*genetics/isolation & purification/*metabolism, Phosphorylation, Recombinant Proteins/genetics/metabolism, Substrate Specificity | Metabolism |
| Proteome | 19000325 | Immunization against Clostridium perfringens cells elicits protection against Clostridium tetani in mouse model: identification of cross-reactive proteins using proteomic methodologies. | Alam SI, Bansod S, Singh L | BMC Microbiol | 10.1186/1471-2180-8-194 | 2008 | Animals, Antibodies, Bacterial/immunology, Bacterial Proteins/*immunology, Bacterial Vaccines/*immunology, Clostridium perfringens/*immunology, Clostridium tetani/*immunology, Cross Reactions, Female, Immunization, Mice, Mice, Inbred BALB C, Proteome/immunology, Proteomics, Tetanus/immunology | |
| Metabolism | 19292998 | Characterization of two putative fibronectin-binding proteins of Clostridium perfringens. | Katayama S, Nozu N, Okuda M, Hirota S, Yamasaki T, Hitsumoto Y | Anaerobe | 10.1016/j.anaerobe.2009.03.001 | 2009 | Bacterial Proteins/genetics/*metabolism, Cloning, Molecular, Clostridium perfringens/genetics/growth & development/isolation & purification/*metabolism, Enzyme-Linked Immunosorbent Assay, Fibronectins/*metabolism, Gas Gangrene/microbiology, Gene Expression Regulation, Bacterial, Humans, Polymerase Chain Reaction, Protein Binding, Recombinant Proteins/genetics/metabolism | Enzymology |
| Metabolism | 19664283 | Differential proteomic analysis of Clostridium perfringens ATCC13124; identification of dominant, surface and structure associated proteins. | Alam SI, Bansod S, Kumar RB, Sengupta N, Singh L | BMC Microbiol | 10.1186/1471-2180-9-162 | 2009 | Animals, Bacterial Outer Membrane Proteins/*metabolism, Clostridium perfringens/*metabolism, Computational Biology, Culture Media, Female, Lyases/metabolism, Mass Spectrometry, Mice, Mice, Inbred BALB C, Ornithine Carbamoyltransferase/metabolism, Proteome/*metabolism, Proteomics | Cultivation |
| Pathogenicity | 20193771 | Virulence for chickens of Clostridium perfringens isolated from poultry and other sources. | Cooper KK, Theoret JR, Stewart BA, Trinh HT, Glock RD, Songer JG | Anaerobe | 10.1016/j.anaerobe.2010.02.006 | 2010 | Animals, Bacterial Toxins/*metabolism, Calcium-Binding Proteins/*metabolism, Cattle, Chickens, Clostridium Infections/microbiology/*veterinary, Clostridium perfringens/isolation & purification/*pathogenicity, Enteritis/microbiology/*veterinary, Humans, Poultry, Poultry Diseases/*microbiology, Species Specificity, Swine, Type C Phospholipases/*metabolism, Virulence | Metabolism |
| Enzymology | 20605988 | Comparative proteomic analysis of extracellular proteins of Clostridium perfringens type A and type C strains. | Sengupta N, Alam SI, Kumar B, Kumar RB, Gautam V, Kumar S, Singh L | Infect Immun | 10.1128/IAI.00374-10 | 2010 | Animals, Bacterial Proteins/*analysis/immunology, Clostridium perfringens/*chemistry/classification/pathogenicity, Electrophoresis, Gel, Two-Dimensional, Female, Mice, Mice, Inbred BALB C, Ornithine Carbamoyltransferase/immunology, Proteomics/*methods, Virulence | Phylogeny |
| Pathogenicity | 20944240 | Comparison of a nontoxic variant of Clostridium perfringens alpha-toxin with the toxic wild-type strain. | Vachieri SG, Clark GC, Alape-Giron A, Flores-Diaz M, Justin N, Naylor CE, Titball RW, Basak AK | Acta Crystallogr D Biol Crystallogr | 10.1107/S090744491003369X | 2010 | Animals, Apoptosis/drug effects/genetics, Bacterial Toxins/*chemistry/genetics/metabolism/toxicity, Calcium-Binding Proteins/*chemistry/genetics/metabolism/toxicity, Catalytic Domain/genetics, Cattle, Cell Line, Cell Membrane/metabolism, Clostridium perfringens/*pathogenicity, Creatine Kinase/blood, Crystallization, Endothelial Cells/*drug effects/pathology, Host-Pathogen Interactions, Humans, Mice, Mice, Inbred Strains, Mutant Proteins/*chemistry/genetics/metabolism/toxicity, Phospholipids/*metabolism, Protein Binding, Protein Conformation, Substrate Specificity/genetics, Type C Phospholipases/*chemistry/genetics/metabolism/toxicity | Metabolism |
| Enzymology | 21085950 | Lytic enzyme discovery through multigenomic sequence analysis in Clostridium perfringens. | Schmitz JE, Ossiprandi MC, Rumah KR, Fischetti VA | Appl Microbiol Biotechnol | 10.1007/s00253-010-2982-8 | 2010 | Amino Acid Sequence, Bacteriophages/*enzymology/genetics, Cloning, Molecular, Clostridium perfringens/enzymology/*genetics/virology, Cluster Analysis, Computational Biology/*methods, Endopeptidases/*genetics/isolation & purification/metabolism, Enzyme Stability, Gene Expression, *Genome, Bacterial, Hydrogen-Ion Concentration, Molecular Sequence Data, Phylogeny, Recombinant Proteins/chemistry/genetics/isolation & purification/metabolism, Sequence Analysis, Sequence Homology, Amino Acid, Temperature | Phylogeny |
| Metabolism | 21905105 | Structural analysis of CPF_2247, a novel alpha-amylase from Clostridium perfringens. | Ficko-Blean E, Stuart CP, Boraston AB | Proteins | 10.1002/prot.23116 | 2011 | Amino Acid Sequence, Bacterial Proteins/*chemistry/genetics/metabolism, Clostridium perfringens/*enzymology, Crystallography, X-Ray, Molecular Sequence Data, Protein Conformation, Protein Structure, Secondary, Protein Structure, Tertiary, Sequence Homology, Amino Acid, alpha-Amylases/*chemistry/genetics/*metabolism | Genetics |
| 22062270 | Use of gamma-irradiation to reduce Clostridium perfringens on ready-to-eat bovine tripe. | Parry-Hanson A, Hall A, Minnaar A, Buys EM | Meat Sci | 10.1016/j.meatsci.2007.06.010 | 2007 | |||
| Pathogenicity | 23452396 | Comparative transcription analysis and toxin production of two fluoroquinolone-resistant mutants of Clostridium perfringens. | Park S, Park M, Rafii F | BMC Microbiol | 10.1186/1471-2180-13-50 | 2013 | Anti-Bacterial Agents/*pharmacology, Bacterial Toxins/*metabolism, Clostridium perfringens/drug effects/*genetics/*metabolism, *Drug Resistance, Bacterial, Fluoroquinolones/*pharmacology, Microarray Analysis, Real-Time Polymerase Chain Reaction, Selection, Genetic, *Transcriptome | Metabolism |
| Pathogenicity | 23668605 | A recombinant carboxy-terminal domain of alpha-toxin protects mice against Clostridium perfringens. | Nagahama M, Oda M, Kobayashi K, Ochi S, Takagishi T, Shibutani M, Sakurai J | Microbiol Immunol | 10.1111/1348-0421.12036 | 2013 | Animals, Antibodies, Bacterial/blood, Antibodies, Neutralizing/blood, Antitoxins/blood, Bacterial Toxins/genetics/*immunology, Bacterial Vaccines/administration & dosage/genetics/*immunology, Calcium-Binding Proteins/genetics/*immunology, Clostridium Infections/immunology/*prevention & control, Clostridium perfringens/*immunology, Disease Models, Animal, Female, Mice, Mice, Inbred BALB C, Neutralization Tests, Recombinant Proteins/genetics/immunology, Survival Analysis, Type C Phospholipases/genetics/*immunology, Vaccines, Synthetic/administration & dosage/genetics/immunology | |
| Pathogenicity | 23789809 | Effect of fluoroquinolone resistance selection on the fitness of three strains of Clostridium perfringens. | Park M, Sutherland JB, Kim JN, Rafii F | Microb Drug Resist | 10.1089/mdr.2013.0056 | 2013 | Anti-Bacterial Agents/*pharmacology, Ciprofloxacin/*pharmacology, Clostridium perfringens/*drug effects/genetics/growth & development, Drug Resistance, Bacterial/genetics, Fluoroquinolones/*pharmacology, Gatifloxacin, Genetic Fitness/*drug effects, Microbial Sensitivity Tests, Microbial Viability/drug effects, Mutation, Norfloxacin/*pharmacology | |
| Pathogenicity | 24083511 | Growth-Inhibiting and morphostructural effects of constituents identified in Asarum heterotropoides root on human intestinal bacteria. | Perumalsamy H, Jung MY, Hong SM, Ahn YJ | BMC Complement Altern Med | 10.1186/1472-6882-13-245 | 2013 | Asarum/*chemistry, Bacteria/*drug effects, Cell Shape/drug effects, Gastrointestinal Tract/drug effects/*microbiology, Humans, Microbial Sensitivity Tests, Microbiota/*drug effects, Plant Extracts/chemistry/*pharmacology, Plant Roots/chemistry | |
| Pathogenicity | 24215704 | Inhibition of Clostridium perfringens growth by potassium lactate during an extended cooling of cooked uncured ground turkey breasts. | Kennedy KM, Milkowski AL, Glass KA | J Food Prot | 10.4315/0362-028X.JFP-13-106 | 2013 | Animals, Clostridium perfringens/drug effects/growth & development/physiology, Cold Temperature, Colony Count, Microbial, Dose-Response Relationship, Drug, Food Contamination/analysis/prevention & control, Food Handling/methods, Food Microbiology, Food Preservation/*methods, Food Preservatives/*pharmacology, Humans, Poultry Products/*microbiology, Sodium Lactate/pharmacology, Turkeys, United States | Biotechnology |
| Enzymology | 26238688 | Comparative analysis of extractable proteins from Clostridium perfringens type A and type C strains showing varying degree of virulence. | Dwivedi P, Alam SI, Kumar O, Kumar RB | Anaerobe | 10.1016/j.anaerobe.2015.07.006 | 2015 | Animals, Bacterial Proteins/*analysis/isolation & purification, Clostridium Infections/microbiology, Clostridium perfringens/*chemistry/pathogenicity, Disease Models, Animal, Electrophoresis, Gel, Two-Dimensional, Mass Spectrometry, Mice, Proteome/*analysis/isolation & purification, Survival Analysis, Virulence, Virulence Factors/*analysis/isolation & purification | Phylogeny |
| Biotechnology | 26492174 | Changes in microbial community during biohydrogen production using gamma irradiated sludge as inoculum. | Yin Y, Wang J | Bioresour Technol | 10.1016/j.biortech.2015.10.027 | 2015 | *Biofuels, *Gamma Rays, Hydrogen/*metabolism, *Microbial Consortia/genetics/radiation effects, Sewage/*microbiology | Metabolism |
| Genetics | 26528533 | Identification of a Bacteria-Specific Binding Protein from the Sequenced Bacterial Genome. | Kong M, Ryu S | J Microbiol Biotechnol | 10.4014/jmb.1510.10056 | 2016 | Amino Acid Sequence, Bacterial Proteins/chemistry/genetics/*metabolism, Carrier Proteins/chemistry/genetics/*metabolism, Clostridium perfringens/chemistry/genetics/*metabolism, *Genome, Bacterial, Molecular Sequence Data, Protein Binding, Protein Structure, Tertiary, Sequence Alignment/*methods | Metabolism |
| Enzymology | 26663202 | Cloning, characterization, and production of three alpha-L-fucosidases from Clostridium perfringens ATCC 13124. | Fan S, Zhang H, Chen X, Lu L, Xu L, Xiao M | J Basic Microbiol | 10.1002/jobm.201500582 | 2015 | Animals, Cloning, Molecular, Clostridium perfringens/*enzymology/*genetics, Enzyme Activation, Escherichia coli/genetics, Fucose/metabolism, Gastric Mucins/metabolism, Glutamic Acid/metabolism, Mutagenesis, Site-Directed, Polysaccharides/metabolism, Substrate Specificity, Swine, alpha-L-Fucosidase/*biosynthesis/*genetics | Metabolism |
| 26761495 | Screening of Bacteriocin-producing Enterococcus faecalis Strains for Antagonistic Activities against Clostridium perfringens. | Han SK, Shin MS, Park HE, Kim SY, Lee WK | Korean J Food Sci Anim Resour | 10.5851/kosfa.2014.34.5.614 | 2014 | |||
| Metabolism | 27038508 | The Details of Glycolipid Glycan Hydrolysis by the Structural Analysis of a Family 123 Glycoside Hydrolase from Clostridium perfringens. | Noach I, Pluvinage B, Laurie C, Abe KT, Alteen MG, Vocadlo DJ, Boraston AB | J Mol Biol | 10.1016/j.jmb.2016.03.020 | 2016 | Catalysis, Catalytic Domain/physiology, Clostridium perfringens/*metabolism, Galactose/metabolism, Glycolipids/*metabolism, Glycoside Hydrolases/*metabolism, Hydrolysis, beta-N-Acetyl-Galactosaminidase/metabolism | |
| Pathogenicity | 27060276 | Ex vivo pharmacokinetic/pharmacodynamic relationship of valnemulin against Clostridium perfringens in plasma, the small intestinal and caecal contents of rabbits. | Zhou YF, Yu Y, Sun J, Tao MT, Zhou WJ, Li X, Liao XP, Liu YH | Anaerobe | 10.1016/j.anaerobe.2016.04.005 | 2016 | Administration, Oral, Animals, Anti-Bacterial Agents/blood/*pharmacokinetics/pharmacology, Cecum/drug effects/microbiology, Clostridium Infections/blood/*drug therapy/microbiology, Clostridium perfringens/*drug effects/growth & development, Diterpenes/blood/pharmacokinetics/pharmacology, Drug Administration Schedule, Female, Half-Life, Injections, Intravenous, Intestine, Small/drug effects/microbiology, Male, Microbial Sensitivity Tests, Rabbits | Enzymology |
| Metabolism | 27353489 | Putative function of hypothetical proteins expressed by Clostridium perfringens type A strains and their protective efficacy in mouse model. | Alam SI, Dwivedi P | Infect Genet Evol | 10.1016/j.meegid.2016.06.040 | 2016 | Animals, Bacterial Proteins/*genetics/*immunology/metabolism, Cloning, Molecular, Clostridium perfringens/genetics/*pathogenicity, Disease Models, Animal, Escherichia coli/genetics, Female, Gas Gangrene/immunology, Mice, Inbred BALB C, Phylogeny, Recombinant Proteins/genetics/immunology/metabolism | Enzymology |
| Enzymology | 27422836 | Efficient and Regioselective Synthesis of beta-GalNAc/GlcNAc-Lactose by a Bifunctional Transglycosylating beta-N-Acetylhexosaminidase from Bifidobacterium bifidum. | Chen X, Xu L, Jin L, Sun B, Gu G, Lu L, Xiao M | Appl Environ Microbiol | 10.1128/AEM.01325-16 | 2016 | Acetylgalactosamine/*metabolism, Acetylglucosamine/*metabolism, Bacteroides fragilis/enzymology/genetics, Bifidobacterium bifidum/*enzymology/genetics, Cloning, Molecular, Clostridium perfringens/enzymology/genetics, Enzyme Stability, Escherichia coli/genetics/metabolism, Gene Expression, Hydrogen-Ion Concentration, Kinetics, Lactose/*metabolism, Molecular Docking Simulation, Recombinant Proteins/chemistry/genetics/isolation & purification/metabolism, Temperature, beta-N-Acetylhexosaminidases/chemistry/genetics/isolation & purification/*metabolism | Metabolism |
| Stress | 28058047 | Effect of Trehalose and Trehalose Transport on the Tolerance of Clostridium perfringens to Environmental Stress in a Wild Type Strain and Its Fluoroquinolone-Resistant Mutant. | Park M, Mitchell WJ, Rafii F | Int J Microbiol | 10.1155/2016/4829716 | 2016 | ||
| Enzymology | 28185856 | Exposure to beta-lactams results in the alteration of penicillin-binding proteins in Clostridium perfringens. | Park M, Rafii F | Anaerobe | 10.1016/j.anaerobe.2017.02.004 | 2017 | Animals, Anti-Bacterial Agents/*pharmacology, Cattle, Chickens, Clostridium Infections/microbiology/veterinary, Clostridium perfringens/*drug effects/*enzymology/isolation & purification, DNA Mutational Analysis, *Mutation, Missense, Penicillin-Binding Proteins/*genetics, Selection, Genetic, *beta-Lactam Resistance, beta-Lactams/*pharmacology | Phylogeny |
| Pathogenicity | 28213749 | Effect of continuous sub-culturing on infectivity of Clostridium perfringens ATCC13124 in mouse gas gangrene model. | Kumar RB, Alam SI | Folia Microbiol (Praha) | 10.1007/s12223-017-0503-1 | 2017 | Animals, Bacterial Proteins/genetics/metabolism, Clostridium perfringens/genetics/growth & development/*physiology, Disease Models, Animal, Gas Gangrene/*microbiology, Host-Pathogen Interactions, Humans, Mice, Mice, Inbred BALB C | Metabolism |
| Metabolism | 28628892 | Structural characterization of wall and lipidated polysaccharides from Clostridium perfringens ATCC 13124. | Vinogradov E, Aubry A, Logan SM | Carbohydr Res | 10.1016/j.carres.2017.06.003 | 2017 | Animals, Cell Wall/*chemistry, Clostridium perfringens/*chemistry/*cytology, *Lipid Metabolism, Lipopolysaccharides/chemistry, Polysaccharides/*chemistry/immunology/*metabolism, Rabbits, Teichoic Acids/chemistry | |
| Enzymology | 29678922 | Enzymatic Synthesis of 6'-Sialyllactose, a Dominant Sialylated Human Milk Oligosaccharide, by a Novel exo-alpha-Sialidase from Bacteroides fragilis NCTC9343. | Guo L, Chen X, Xu L, Xiao M, Lu L | Appl Environ Microbiol | 10.1128/AEM.00071-18 | 2018 | Bacteroides fragilis/*enzymology/*genetics, Bifidobacterium bifidum/enzymology/genetics, Cloning, Molecular, Clostridium perfringens/enzymology/genetics, Escherichia coli/genetics, Gene Expression Regulation, Bacterial, Humans, Hydrogen-Ion Concentration, Infant Formula, Lactose/*analogs & derivatives/biosynthesis/metabolism, Milk, Human/*chemistry, Models, Molecular, Molecular Weight, Neuraminidase/*genetics/isolation & purification/*metabolism, Oligosaccharides/*metabolism, Protein Domains, Recombinant Proteins, Sequence Alignment, Sequence Analysis, Sialic Acids/metabolism, Substrate Specificity, Temperature, Time Factors | Metabolism |
| 29725227 | Inhibition of Clostridium perfringens using Bacteriophages and Bacteriocin Producing Strains. | Heo S, Kim MG, Kwon M, Lee HS, Kim GB | Korean J Food Sci Anim Resour | 10.5851/kosfa.2018.38.1.88 | 2018 | |||
| Biotechnology | 30637638 | Evaluation of Lactobacillus plantarum encapsulated with Eleutherine americana oligosaccharide extract as food additive in yoghurt. | Phoem AN, Mayiding A, Saedeh F, Permpoonpattana P | Braz J Microbiol | 10.1007/s42770-018-0017-2 | 2018 | Food Additives/*chemistry, Food Microbiology/*methods, Iridaceae/*chemistry, Lactobacillus plantarum/*chemistry/growth & development, Microbial Viability, Oligosaccharides/*chemistry, Plant Extracts/*chemistry, Probiotics/*chemistry, Yogurt/*analysis/microbiology | |
| Pathogenicity | 30669805 | [A study on clinical application of a novel reagent detecting toxigenic strains of Clostridium difficile]. | Wang SM, Wang ZY | Zhonghua Yi Xue Za Zhi | 10.3760/cma.j.issn.0376-2491.2018.48.013 | 2018 | Bacterial Toxins, *Clostridioides difficile, *Clostridium Infections, Feces, Humans, Polymerase Chain Reaction | |
| 31333591 | Galleria mellonella Infection Model Identifies Both High and Low Lethality of Clostridium perfringens Toxigenic Strains and Their Response to Antimicrobials. | Kay S, Edwards J, Brown J, Dixon R | Front Microbiol | 10.3389/fmicb.2019.01281 | 2019 | |||
| Phylogeny | 31683584 | Capsular Polysaccharide Is a Receptor of a Clostridium perfringens Bacteriophage CPS1. | Ha E, Chun J, Kim M, Ryu S | Viruses | 10.3390/v11111002 | 2019 | Bacterial Capsules/chemistry/genetics, Bacterial Proteins/genetics, *Bacteriophages/genetics/isolation & purification, Carbohydrate Epimerases/genetics, Clostridium perfringens/genetics/*virology, Genes, Bacterial, Genome, Viral, Phylogeny, *Podoviridae/classification/genetics/isolation & purification/ultrastructure, Polysaccharides, Bacterial/*genetics, Receptors, Virus/*genetics, UDPglucose 4-Epimerase/genetics | Enzymology |
| Pathogenicity | 32088319 | beta-Lactam resistance development affects binding of penicillin-binding proteins (PBPs) of Clostridium perfringens to the fluorescent penicillin, BOCILLIN FL. | Park M, Sutherland JB, Rafii F | Anaerobe | 10.1016/j.anaerobe.2020.102179 | 2020 | Anti-Bacterial Agents/pharmacology, Bacterial Proteins/genetics, Clostridium Infections/*diagnosis/*microbiology, Clostridium perfringens/drug effects/*genetics, Gene Expression Regulation, Bacterial, Humans, Penicillin-Binding Proteins/*genetics, Penicillins/pharmacology, Real-Time Polymerase Chain Reaction, *beta-Lactam Resistance | |
| Phylogeny | 32097777 | Antibiotic resistance, genome analysis and further safe traits of Clostridium perfringens ICVB082; a strain capable of producing an inhibitory compound directed only against a closely related pathogenic strain. | Vieco-Saiz N, Belguesmia Y, Vachee A, Le Marechal C, Salvat G, Drider D | Anaerobe | 10.1016/j.anaerobe.2020.102177 | 2020 | Animals, Anti-Bacterial Agents/*pharmacology, Antibiosis, Bacterial Toxins/genetics, Clostridium Infections/*veterinary, Clostridium perfringens/*drug effects/*genetics/pathogenicity, *Drug Resistance, Bacterial, Drug Resistance, Multiple, Bacterial, *Genome, Bacterial, Hemolysis, Phylogeny, Poultry Diseases/microbiology, RNA, Ribosomal, 16S, Virulence, Virulence Factors | Pathogenicity |
| Phylogeny | 32388703 | Biodiversity and Phylogenetic Relationships of Novel Bacteriocinogenic Strains Isolated from Animal's Droppings at the Zoological Garden of Lille, France. | Eveno M, Salouhi A, Belguesmia Y, Bazinet L, Gancel F, Fliss I, Drider D | Probiotics Antimicrob Proteins | 10.1007/s12602-020-09657-4 | 2021 | Animals, Animals, Zoo/*microbiology, *Bacteria/classification/genetics/isolation & purification/metabolism, *Bacteriocins/biosynthesis/genetics, *Biodiversity, Feces/*microbiology, France, *Phylogeny | Enzymology |
| Phylogeny | 33451155 | Dual Inhibition of Salmonella enterica and Clostridium perfringens by New Probiotic Candidates Isolated from Chicken Intestinal Mucosa. | Lone A, Mottawea W, Ait Chait Y, Hammami R | Microorganisms | 10.3390/microorganisms9010166 | 2021 | ||
| Pathogenicity | 33734645 | In-laboratory quality control of nutrients for automatic bacteriology analyzer YUNON(R)Labstar 50. | Boronina LG, Samatova EV, Kukushkina MP, Panova SA, Ustyugova SS | Klin Lab Diagn | 10.51620/0869-2084-2021-66-2-110-114 | 2021 | Anti-Bacterial Agents, *Bacterial Infections, *Bacteriology, Child, Humans, Laboratories, Microbial Sensitivity Tests, Nutrients, Quality Control | |
| 36185515 | Immunogenicity of a newly developed vaccine against Clostridium perfringens alpha-toxin in rabbits and cattle. | Saadh MJ, Lafi FF, Dahadha AA, Albannan MS | Vet World | 10.14202/vetworld.2022.1617-1623 | 2022 |
Reference
| @id | authors | catalogue | doi/url | title | journal | pubmed |
|---|---|---|---|---|---|---|
| 428 | Curators of the DSMZ | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 756) | https://www.dsmz.de/collection/catalogue/details/culture/DSM-756 | |||
| 20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M. | 10.1099/ijsem.0.004332 | List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ | |||
| 20218 | Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P. | 10.1016/j.syapm.2013.11.002 | StrainInfo introduces electronic passports for microorganisms. | Syst Appl Microbiol. 37: 42-50 2014 | 24321274 | |
| 42056 | Curators of the CIP | https://brclims.pasteur.fr/brcWeb/souche/detail/1/15204 | ||||
| 44424 | Curators of the CCUG | Culture Collection University of Gothenburg (CCUG) (CCUG 1795) | https://www.ccug.se/strain?id=1795 | |||
| 66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | https://diaspora-project.de/progress.html#genomes | Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | |||
| 67770 | Curators of the JCM | https://jcm.brc.riken.jp/en/ | ||||
| 68367 | Automatically annotated from API 20A | |||||
| 68380 | Automatically annotated from API rID32A | |||||
| 69479 | João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich. | https://microbeatlas.org/ | MicrobeAtlas 1.0 beta | |||
| 69480 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | https://diaspora-project.de/progress.html#genomes | Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | |||
| 69481 | Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch | 10.21203/rs.3.rs-2527258/v1 | Predictions based on the model GenomeNet Sporulation v. 1 | |||
| 72162 | Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J. | 10.60712/SI-ID289341.1 | StrainInfo: A central database for resolving microbial strain identifiers |