Strain identifier

BacDive ID: 1757

Type strain: Yes

Species: Gardnerella vaginalis

Strain Designation: 594

Strain history: CIP <- 1974, NCTC <- 1962, K. Zinnemann Leeds <- C.D. Dukes, Haemophilus vaginalis: strain 594

NCBI tax ID(s): 585528 (strain), 2702 (species)

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General

@ref: 1884

BacDive-ID: 1757

DSM-Number: 4944

keywords: genome sequence, 16S sequence, Bacteria, anaerobe, thermophilic, Gram-variable, colony-forming

description: Gardnerella vaginalis 594 is an anaerobe, thermophilic, Gram-variable bacterium that forms round colonies and was isolated from vaginal secretions.

NCBI tax id

NCBI tax idMatching level
2702species
585528strain

strain history

@refhistory
1884<- ATCC <- C.D. Dukes, 594
67770CIP 70.74 <-- NCTC 10287 <-- K. Zimmermann Leeds <-- C. D. Dukes 594.
123778CIP <- 1974, NCTC <- 1962, K. Zinnemann Leeds <- C.D. Dukes, Haemophilus vaginalis: strain 594

doi: 10.13145/bacdive1757.20230509.8.1

Name and taxonomic classification

LPSN

  • @ref: 20215
  • description: domain/bacteria
  • keyword: phylum/actinomycetota
  • domain: Bacteria
  • phylum: Actinomycetota
  • class: Actinomycetes
  • order: Bifidobacteriales
  • family: Bifidobacteriaceae
  • genus: Gardnerella
  • species: Gardnerella vaginalis
  • full scientific name: Gardnerella vaginalis (Gardner and Dukes 1955) Greenwood and Pickett 1980

  • synonyms

    @refsynonym
    20215Corynebacterium vaginale
    20215Haemophilus vaginalis

@ref: 1884

domain: Bacteria

phylum: Actinobacteria

class: Actinobacteria

order: Bifidobacteriales

family: Bifidobacteriaceae

genus: Gardnerella

species: Gardnerella vaginalis

full scientific name: Gardnerella vaginalis (Gardner and Dukes 1955) Greenwood and Pickett 1980 emend. Nouioui et al. 2018 emend. Vaneechoutte et al. 2019

strain designation: 594

type strain: yes

Morphology

cell morphology

@refgram staincell lengthcell widthmotilityconfidencecell shape
22917variable1.5 µm0.5 µm
69480no92.218
69480positive99.999
123778negativenorod-shaped

colony morphology

@refcolony colorcolony shapehemolysis ability
22917opaqueround
1237781

Culture and growth conditions

culture medium

@refnamegrowthlinkcomposition
1884COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)yeshttps://mediadive.dsmz.de/medium/693Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base
1884BHI MEDIUM (DSMZ Medium 215)yeshttps://mediadive.dsmz.de/medium/215Name: BHI MEDIUM (DSMZ Medium 215; with strain-specific modifications) Composition: Brain heart infusion 37.0 g/l Maltose 10.0 g/l Distilled water
36208MEDIUM 252 - for Gardnerella and Propionibacterium lymphophilumyesDistilled water make up to (1000.000 ml);Horse serum (200.000 ml);Brainheart infusion agar (37.000 g);Maltose 10 % solution - M0173 (200.000 ml)
123778CIP Medium 252yeshttps://catalogue-crbip.pasteur.fr/fiche_milieu.xhtml?crbip=252
123778CIP Medium 26yeshttps://catalogue-crbip.pasteur.fr/fiche_milieu.xhtml?crbip=26

culture temp

@refgrowthtypetemperaturerange
22917positivemaximum42thermophilic
22917positiveminimum25mesophilic
1884positivegrowth37mesophilic
36208positivegrowth37mesophilic
44687positivegrowth37mesophilic
67770positivegrowth37mesophilic
123778positivegrowth30-41
123778nogrowth10psychrophilic
123778nogrowth15psychrophilic
123778nogrowth25mesophilic
123778nogrowth45thermophilic

culture pH

@refabilitytypepH
22917positiveminimum4.5
22917positiveoptimum6 - 6.5

Physiology and metabolism

oxygen tolerance

@refoxygen toleranceconfidence
1884anaerobe
1884microaerophile
44687anaerobe
44687microaerophile
69480anaerobe99.999
123778facultative anaerobe

spore formation

@refspore formationconfidence
69481no100
69480no99.997

compound production

  • @ref: 22917
  • compound: Acetic acid

halophily

@refsaltgrowthtested relationconcentration
123778NaClpositivegrowth0 %
123778NaClnogrowth2 %
123778NaClnogrowth4 %
123778NaClnogrowth6 %
123778NaClnogrowth8 %
123778NaClnogrowth10 %

metabolite utilization

@refChebi-IDmetaboliteutilization activitykind of utilization tested
2291718305arbutin-builds acid from
2291717057cellobiose-builds acid from
2291723652dextrin+builds acid from
2291728757fructose+builds acid from
2291728260galactose+builds acid from
2291717234glucose+builds acid from
2291717268myo-inositol-builds acid from
2291717716lactose+fermentation
2291717306maltose+builds acid from
2291729864mannitol-builds acid from
2291737684mannose+builds acid from
2291726546rhamnose-builds acid from
2291733942ribose+builds acid from
2291730911sorbitol-builds acid from
2291728017starch+builds acid from
2291717992sucrose+fermentation
2291718222xylose+fermentation
2291717632nitrate-reduction
2291715956biotin+required for growth
2291762501folate+required for growth
2291717154nicotinamide+required for growth
2291726948thiamine+required for growth
2291717015riboflavin+required for growth
6836817632nitrate-reduction
6836828053melibiose-fermentation
6836817992sucrose-fermentation
6836862345L-rhamnose-fermentation
6836830911sorbitol-fermentation
6836817268myo-inositol-fermentation
6836817634D-glucose-fermentation
683685291gelatin-hydrolysis
6836827897tryptophan-energy source
6836816199urea-hydrolysis
6836816947citrate-assimilation
6836818257ornithine-degradation
6836825094lysine-degradation
6836829016arginine-hydrolysis
12377816947citrate-carbon source
1237784853esculin-hydrolysis
123778606565hippurate+hydrolysis
12377817632nitrate-reduction
12377816301nitrite-reduction
12377835020tributyrin+hydrolysis
12377817632nitrate+respiration
683764853esculin-hydrolysis
6837618333D-arabitol-builds acid from
6837665327D-xylose-builds acid from
6837662345L-rhamnose-builds acid from
68376320061methyl alpha-D-glucopyranoside-builds acid from
6837616988D-ribose-builds acid from
6837629042glucose 1-phosphate-builds acid from
6837616443D-tagatose-builds acid from
6837717634D-glucose+builds acid from
6837715824D-fructose+builds acid from
6837717306maltose+builds acid from
6837717992sucrose-builds acid from
6837718257ornithine-degradation
6837716199urea-hydrolysis
6837727897tryptophan-energy source
6838016199urea-hydrolysis
6838029016arginine-hydrolysis
6838017632nitrate-reduction
6838027897tryptophan-energy source
6838129016arginine-hydrolysis
6838116988D-ribose-builds acid from
6838116899D-mannitol-builds acid from
6838130911sorbitol-builds acid from
6838117716lactose-builds acid from
6838127082trehalose-builds acid from
6838116634raffinose-builds acid from
6838117992sucrose-builds acid from
6838130849L-arabinose-builds acid from
6838118333D-arabitol-builds acid from
6838140585alpha-cyclodextrin-builds acid from
6838128087glycogen-builds acid from
6838127941pullulan-builds acid from
6838117306maltose-builds acid from
6838128053melibiose-builds acid from
683816731melezitose-builds acid from
68381320055methyl beta-D-glucopyranoside-builds acid from
6838116443D-tagatose-builds acid from
6838116199urea-hydrolysis

antibiotic resistance

  • @ref: 123778
  • metabolite: 0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate)
  • is antibiotic: yes
  • is sensitive: yes
  • is resistant: no

metabolite production

@refChebi-IDmetaboliteproduction
2291735581indoleno
2291730089acetateyes
6837735581indoleno
6836817997dinitrogenno
6836816301nitriteno
6836815688acetoinno
6836835581indoleno
6836816136hydrogen sulfideno
12377835581indoleno
6838035581indoleno
6838115688acetoinno

metabolite tests

@refChebi-IDmetabolitevoges-proskauer-testindole testmethylred-test
6838115688acetoin-
6838035581indole-
6837735581indole-
6836815688acetoin-
6836835581indole-
12377815688acetoin-
12377817234glucose+

enzymes

@refvalueactivityec
22917catalase-1.11.1.6
22917cytochrome oxidase-1.9.3.1
22917urease-3.5.1.5
68382alpha-fucosidase-3.2.1.51
68382alpha-mannosidase-3.2.1.24
68382N-acetyl-beta-glucosaminidase-3.2.1.52
68382beta-glucosidase-3.2.1.21
68382alpha-glucosidase+3.2.1.20
68382beta-glucuronidase-3.2.1.31
68382beta-galactosidase+3.2.1.23
68382alpha-galactosidase-3.2.1.22
68382naphthol-AS-BI-phosphohydrolase-
68382acid phosphatase+3.1.3.2
68382alpha-chymotrypsin-3.4.21.1
68382trypsin-3.4.21.4
68382cystine arylamidase-3.4.11.3
68382valine arylamidase-
68382leucine arylamidase+3.4.11.1
68382lipase (C 14)-
68382alkaline phosphatase-3.1.3.1
68381urease-3.5.1.5
68381beta-mannosidase-3.2.1.25
68381glycyl tryptophan arylamidase-
68381N-acetyl-beta-glucosaminidase-3.2.1.52
68381pyrrolidonyl arylamidase-3.4.19.3
68381beta-galactosidase+3.2.1.23
68381Alanyl-Phenylalanyl-Proline arylamidase+
68381alkaline phosphatase+3.1.3.1
68381alpha-galactosidase-3.2.1.22
68381beta-glucuronidase-3.2.1.31
68381beta-glucosidase-3.2.1.21
68381arginine dihydrolase-3.5.3.6
68380glutamyl-glutamate arylamidase-
68380pyrrolidonyl arylamidase-3.4.19.3
68380proline-arylamidase+3.4.11.5
68380alkaline phosphatase-3.1.3.1
68380tryptophan deaminase-4.1.99.1
68380N-acetyl-beta-glucosaminidase-3.2.1.52
68380beta-glucuronidase-3.2.1.31
68380alpha-arabinosidase-3.2.1.55
68380beta-glucosidase-3.2.1.21
68380beta-Galactosidase 6-phosphate-
68380alpha-galactosidase-3.2.1.22
68380arginine dihydrolase-3.5.3.6
68380urease-3.5.1.5
68377tryptophan deaminase-4.1.99.1
68377gamma-glutamyltransferase-2.3.2.2
68377proline-arylamidase+3.4.11.5
68377beta-galactosidase-3.2.1.23
68377alkaline phosphatase-3.1.3.1
68377lipase-
68377urease-3.5.1.5
68377ornithine decarboxylase-4.1.1.17
68377beta-lactamase-3.5.2.6
68376alpha-mannosidase-3.2.1.24
68376beta-glucosidase-3.2.1.21
68368gelatinase-
68368tryptophan deaminase-4.1.99.1
68368urease-3.5.1.5
68368ornithine decarboxylase-4.1.1.17
68368lysine decarboxylase-4.1.1.18
68368arginine dihydrolase-3.5.3.6
68368beta-galactosidase-3.2.1.23
123778oxidase-
123778beta-galactosidase+3.2.1.23
123778alcohol dehydrogenase-1.1.1.1
123778gelatinase-
123778amylase-
123778DNase-
123778caseinase-3.4.21.50
123778catalase-1.11.1.6
123778tween esterase+
123778gamma-glutamyltransferase-2.3.2.2
123778lecithinase-
123778lipase-
123778lysine decarboxylase-4.1.1.18
123778ornithine decarboxylase-4.1.1.17
123778phenylalanine ammonia-lyase-4.3.1.24
123778protease-
123778tryptophan deaminase-
123778urease-3.5.1.5

API zym

@refControlAlkaline phosphataseEsteraseEsterase LipaseLipaseLeucine arylamidaseValine arylamidaseCystine arylamidaseTrypsinalpha- ChymotrypsinAcid phosphataseNaphthol-AS-BI-phosphohydrolasealpha- Galactosidasebeta- Galactosidasebeta- Glucuronidasealpha- Glucosidasebeta- GlucosidaseN-acetyl-beta- glucosaminidasealpha- Mannosidasealpha- Fucosidase
44687-----+----+--+-+----
123778--++-+----+--+-+----

API 20E

@refONPGADH ArgLDC LysODCCITH2SURETDA TrpINDVPGELGLUINOSorRHASACMELNO2N2
123778-------------------

API LIST

@refDIMESCalpha MANDARLXYLRHAMDGRIBG1PTAG
123778----------

API NH

@refPENGLUFRUMALSACODCURELIPPALbeta GALProAGGTIND
44687-+++------+--

API rID32A

@refUREADH Argalpha GALbeta GALbeta GPalpha GLUbeta GLUalpha ARAbeta GURbeta NAGMNERAFGDCalpha FUCNITINDPALArgAProALGAPheALeuAPyrATyrAAlaAGlyAHisAGGASerA
1884---+/--+-----------+/-+-+/---+/------
1884---+-+------++---+++/-++-++/-+/-+-+/-
1884------------------+----------
1884---+-+----++/------++-++-++/-+/-+-+
1884---+-+-----------++-++-++/-+/-+-+/-
1884---+-+----+/-+/------++-++-+-----
44687---+-+-----------+++++-++++--
1884---+-+----++-----++-++-++++-+

API rID32STR

@refADH Argbeta GLUbeta GARbeta GURalpha GALPALRIBMANSORLACTRERAFSACLARADARLCDEXVPAPPAbeta GALPyrAbeta NAGGTAHIPGLYGPULMALMELMLZMbeta DGTAGbeta MANURE
1884--+--+-----------++---+/----------

API biotype100

@refGLUFRUGALTREMNESBEMELSACRAFMTEMALLACLTEMbGaMaGaCELGENMbGuESCRIBARAXYLPLERHAFUCMLZDARLLARLXLTDULTAGGLYINOMANMTLTURSORADOHBGLYXERYMDG3MDGSATMUCLTATDTATMTATDMLTLMLTCATETATETTECITGRTGAT2KG5KGTRYNAGGNTPACPATpOBEQATGTEmOBEBATPPATCMTTGEBETPCEABTHINLATCAPCYTHISSUCFUMGREGYTAVTETNTTNGLNITA3OBUAPTGTTPRODALALALASERMNTPROPTYR2KT
123778---------------------------------------------------------------------------------------------------

Isolation, sampling and environmental information

isolation

@refsample typecountryorigin.countrycontinent
1884vaginal secretions
44687Human vaginaUSAUSANorth America
67770Human genital tract
123778Vaginal secretions

isolation source categories

Cat1Cat2Cat3
#Host Body-Site#Urogenital tract#Vagina
#Host Body Product#Urogenital tract#Vaginal secretion

taxonmaps

  • @ref: 69479
  • File name: preview.99_404.png
  • url: https://microbeatlas.org/index.html?action=taxon&taxon_id=90_24;96_274;97_302;98_336;99_404&stattab=map
  • Last taxonomy: Gardnerella vaginalis
  • 16S sequence: JQ354968
  • Sequence Identity:
  • Total samples: 58380
  • soil counts: 1125
  • aquatic counts: 1865
  • animal counts: 54923
  • plant counts: 467

Safety information

risk assessment

@refbiosafety levelbiosafety level comment
18842Risk group (German classification)
1237782Risk group (French classification)

Sequence information

16S sequences

@refdescriptionaccessionlengthdatabaseNCBI tax ID
20218Gardnerella vaginalis genes for 16S rRNA, ITS, 23S rRNA, strain: ATCC 14018AB547907728ena585528
20218Gardnerella vaginalis ATCC 14018 = JCM 11026 16S ribosomal RNA gene, partial sequenceJQ3549681364ena585528
20218Gardnerella vaginalis ATCC 14018 = JCM 11026 16S ribosomal RNA gene, partial sequenceM587441475ena585528
67770Gardnerella vaginalis gene for 16S ribosomal RNA, partial sequence, strain: JCM 11026AB9718201489ena585528

Genome sequences

@refdescriptionaccessionassembly leveldatabaseNCBI tax ID
66792Gardnerella vaginalis NCTC10287GCA_900637625completencbi2702
66792Gardnerella vaginalis ATCC 14018 = JCM 11026GCA_001042655completencbi585528
66792Gardnerella vaginalis DSM 4944GCA_900105405chromosomencbi2702
66792Gardnerella vaginalis ATCC 14018 = JCM 11026585528.15wgspatric585528
66792Gardnerella vaginalis ATCC 14018 = JCM 11026585528.19wgspatric585528
66792Gardnerella vaginalis ATCC 14018 = JCM 11026585528.11completepatric585528
66792Gardnerella vaginalis ATCC 14018 = JCM 11026585528.6wgspatric585528
66792Gardnerella vaginalis strain DSM 49442702.105completepatric2702
66792Gardnerella vaginalis strain NCTC102872702.194completepatric2702
66792Gardnerella vaginalis ATCC 140182854645441draftimg585528
66792Gardnerella vaginalis ATCC 14018648276678draftimg585528
66792Gardnerella vaginalis NCTC102872841333980completeimg2702
66792Gardnerella vaginalis DSM 49442630968301draftimg2702
67770Gardnerella vaginalis ATCC 14018 = JCM 11026GCA_000178355scaffoldncbi585528
67770Gardnerella vaginalis ATCC 14018 = JCM 11026GCA_003397685contigncbi585528
67770Gardnerella vaginalis ATCC 14018 = JCM 11026GCA_004336685contigncbi585528

GC content

@refGC-contentmethod
2291743.1Buoyant density centrifugation (BD)
6777043high performance liquid chromatography (HPLC)

Genome-based predictions

predictions

traitpredictionconfidencetraining_data
spore-formingno100no
motileno94.511no
flagellatedno96.599no
gram-positiveyes55.436yes
anaerobicyes94.967no
aerobicno97.598yes
halophileno60.01no
spore-formingno96.618no
thermophileno88.281no
glucose-utilyes88.234no
glucose-fermentyes79.749no

External links

@ref: 1884

culture collection no.: DSM 4944, ATCC 14018, CCUG 3717, NCTC 10915, NCTC 10287, LMG 7832, JCM 11026, BCRC 17040, CIP 70.74, KCTC 5096, LMG 14323

straininfo link

  • @ref: 71404
  • straininfo: 92252

literature

topicPubmed-IDtitleauthorsjournalDOIyearmeshtopic2
Phylogeny1410795Heterogeneity in restriction patterns of Gardnerella vaginalis isolates from individuals with bacterial vaginosis.Nath K, Devlin D, Beddoe AMRes Microbiol10.1016/0923-2508(92)90009-d1992Bacterial Typing Techniques, DNA, Bacterial/*classification/genetics, Electrophoresis, Agar Gel, Female, Gardnerella vaginalis/*classification/genetics/isolation & purification, Humans, In Vitro Techniques, Prohibitins, Restriction Mapping, Vaginosis, Bacterial/*classification/genetics/microbiologyEnzymology
Pathogenicity1947429The characterization of Gardnerella vaginalis DNA using non-radioactive DNA probes.Nath K, Choi DJ, Devlin DRes Microbiol10.1016/0923-2508(91)90190-l1991Blotting, Southern, DNA Probes/*analysis, DNA, Bacterial/*analysis, Female, Gardnerella vaginalis/*genetics, Humans, Immunoenzyme Techniques, In Vitro Techniques, Restriction Mapping
Pathogenicity6607519Characterization of Gardnerella vaginalis by gas chromatography.Csango PA, Hagen N, Jagars GScand J Infect Dis Suppl1983Agar, Animals, Blood, Chromatography, Gas/methods, Fatty Acids/analysis, Female, Gardnerella vaginalis/*analysis/growth & development/isolation & purification, Haemophilus/*analysis, Haemophilus Infections/microbiology, Hemolysis, Humans, In Vitro Techniques, Sheep, Vaginitis/microbiologyEnzymology
Enzymology7584037Determination of Gardnerella vaginalis genome size by pulsed-field gel electrophoresis.Lim D, Trivedi H, Nath KDNA Res10.1093/dnares/1.3.1151994Base Sequence, DNA Restriction Enzymes, DNA, Bacterial/chemistry, Electrophoresis, Gel, Pulsed-Field, Gardnerella vaginalis/*genetics, *Genome, Bacterial, Molecular Sequence Data, Molecular WeightGenetics
Phylogeny9097423Identification and quantification of Bifidobacterium species isolated from food with genus-specific 16S rRNA-targeted probes by colony hybridization and PCR.Kaufmann P, Pfefferkorn A, Teuber M, Meile LAppl Environ Microbiol10.1128/aem.63.4.1268-1273.19971997Bacterial Typing Techniques, Bifidobacterium/classification/genetics/*isolation & purification, DNA Probes, *Food Microbiology, Molecular Probe Techniques, Molecular Sequence Data, Polymerase Chain Reaction, RNA, Bacterial/*analysis/genetics, RNA, Ribosomal, 16S/*analysis/geneticsBiotechnology
Phylogeny9858460Phylogenetic analysis of the genus Bifidobacterium and related genera based on 16S rDNA sequences.Miyake T, Watanabe K, Watanabe T, Oyaizu HMicrobiol Immunol10.1111/j.1348-0421.1998.tb02337.x1998Base Sequence, Bifidobacterium/classification/*genetics, *DNA, Bacterial, *DNA, Ribosomal, Databases, Factual, Humans, Molecular Sequence Data, Phylogeny, *RNA, Ribosomal, 16SPathogenicity
Enzymology11107902[The production of a latex immunoglobulin conjugate for the diagnosis of Gardnerella vaginalis].Espinosa I, Alvarez E, Amaral C, Alonso M, Lorenzo MRev Cubana Med Trop2000Animals, Antigens, Bacterial/analysis/immunology, Electrophoresis, Polyacrylamide Gel, Female, Gardnerella vaginalis/*immunology, Humans, Immune Sera/analysis/isolation & purification, Immunization/methods, Immunoblotting, *Immunoglobulins/isolation & purification, *Latex, Latex Fixation Tests/methods, Sheep, Vaginosis, Bacterial/*diagnosisPathogenicity
Pathogenicity11851605A study to detect Gardnerella vaginalis DNA in interstitial cystitis.Agarwal M, Dixon RABJU Int10.1046/j.1464-4096.2001.01441.x2001Cystitis, Interstitial/diagnosis/*microbiology, DNA, Bacterial/*analysis, Female, Gardnerella vaginalis/*genetics/isolation & purification, Humans, Polymerase Chain Reaction/methods, Vaginosis, Bacterial/complications/*diagnosisEnzymology
Pathogenicity16907815In vitro antibacterial activity of Lactobacillus helveticus strain KS300 against diarrhoeagenic, uropathogenic and vaginosis-associated bacteria.Atassi F, Brassart D, Grob P, Graf F, Servin ALJ Appl Microbiol10.1111/j.1365-2672.2006.02933.x2006Bacterial Adhesion/physiology, Caco-2 Cells, Coculture Techniques/methods, Diarrhea/diet therapy/*microbiology, Escherichia coli/growth & development, Female, Gardnerella vaginalis/growth & development, HeLa Cells, Humans, Lactobacillus helveticus/*physiology, Prevotella/growth & development, Probiotics/*therapeutic use, Salmonella typhimurium/growth & development, Urologic Diseases/diet therapy/*microbiology, Vaginosis, Bacterial/diet therapy/*microbiology
Metabolism20082639Individual and co-operative roles of lactic acid and hydrogen peroxide in the killing activity of enteric strain Lactobacillus johnsonii NCC933 and vaginal strain Lactobacillus gasseri KS120.1 against enteric, uropathogenic and vaginosis-associated pathogens.Atassi F, Servin ALFEMS Microbiol Lett10.1111/j.1574-6968.2009.01887.x2009Anti-Bacterial Agents/metabolism/pharmacology, *Antibiosis, Drug Synergism, Enterobacteriaceae/classification/growth & development/metabolism, Female, Gardnerella vaginalis/drug effects/growth & development, Humans, *Hydrogen Peroxide/metabolism/pharmacology, *Lactic Acid/metabolism/pharmacology, *Lactobacillus/classification/growth & development/metabolism, Salmonella Infections/microbiology/prevention & control, *Salmonella typhimurium/drug effects/growth & development, Urinary Tract Infections/microbiology/prevention & control, *Uropathogenic Escherichia coli/drug effects/growth & development, Vagina/microbiology, Vaginosis, Bacterial/microbiology/prevention & controlPathogenicity
Genetics20865041Comparative genomics of Gardnerella vaginalis strains reveals substantial differences in metabolic and virulence potential.Yeoman CJ, Yildirim S, Thomas SM, Durkin AS, Torralba M, Sutton G, Buhay CJ, Ding Y, Dugan-Rocha SP, Muzny DM, Qin X, Gibbs RA, Leigh SR, Stumpf R, White BA, Highlander SK, Nelson KE, Wilson BAPLoS One10.1371/journal.pone.00124112010Bacterial Proteins/genetics/metabolism, Female, Gardnerella vaginalis/classification/*genetics/*metabolism/pathogenicity, *Genomics, Humans, Male, Molecular Sequence Data, Phylogeny, Vagina/microbiology, Vaginosis, Bacterial/*microbiology, VirulencePhylogeny
Pathogenicity23880127Plants traditionally used individually and in combination to treat sexually transmitted infections in northern Maputaland, South Africa: antimicrobial activity and cytotoxicity.Naidoo D, van Vuuren SF, van Zyl RL, de Wet HJ Ethnopharmacol10.1016/j.jep.2013.07.0182013Anti-Infective Agents/administration & dosage/pharmacology/*therapeutic use/toxicity, Cell Survival/drug effects, Drug Synergism, Drug Therapy, Combination, HEK293 Cells, Humans, *Medicine, African Traditional, Microbial Sensitivity Tests, Plant Extracts/administration & dosage/pharmacology/*therapeutic use/toxicity, Plants, Medicinal/*chemistry, Sexually Transmitted Diseases/*drug therapy/*microbiology, South Africa, Treatment Outcome
Phylogeny24813010Inhibitory effects of seaweed extracts on the growth of the vaginal bacterium Gardnerella vaginalis.Ha YM, Choi JS, Lee BB, Moon HE, Cho KK, Choi ISJ Environ Biol2014Anti-Bacterial Agents/chemistry/*pharmacology, Gardnerella vaginalis/*drug effects, Plant Extracts/chemistry/*pharmacology, Seaweed/*chemistry/classification, Species SpecificityPathogenicity
Genetics25858849Complete Genome Sequence of Gardnerella vaginalis Strain JCM 11026T, Isolated from Vaginal Tracts of Women.Oshima K, Hisamatsu S, Toh H, Nakano A, Kiuchi M, Kuroyanagi H, Morita H, Hattori MGenome Announc10.1128/genomeA.00286-152015Phylogeny
Pathogenicity28893789Gemini Cationic Amphiphiles Control Biofilm Formation by Bacterial Vaginosis Pathogens.Algburi A, Zhang Y, Weeks R, Comito N, Zehm S, Pinto J, Uhrich KE, Chikindas MLAntimicrob Agents Chemother10.1128/AAC.00650-172017Anti-Bacterial Agents/*pharmacology, Bacterial Adhesion/drug effects, Biofilms/*growth & development, Drug Synergism, Female, Gardnerella vaginalis/*drug effects, Humans, Lactobacillus plantarum/*drug effects, Metronidazole/pharmacology, Microbial Sensitivity Tests, Surface-Active Agents/*pharmacology, Vagina/microbiology, Vaginosis, Bacterial/*drug therapy/microbiology
Pathogenicity30057443Benzoyl Peroxide Inhibits Quorum Sensing and Biofilm Formation by Gardnerella vaginalis 14018.Algburi A, Zehm S, Netrebov V, Weeks R, Zubovskiy K, Chikindas MLInfect Dis Obstet Gynecol10.1155/2018/14261092018Anti-Bacterial Agents/*pharmacology, Benzoyl Peroxide/*pharmacology, Biofilms/*drug effects, Female, Gardnerella vaginalis/*drug effects/physiology, Humans, Quorum Sensing/*drug effects, Salicylic Acid/pharmacology, Vaginosis, Bacterial/drug therapy
Phylogeny30648938Emended description of Gardnerella vaginalis and description of Gardnerella leopoldii sp. nov., Gardnerella piotii sp. nov. and Gardnerella swidsinskii sp. nov., with delineation of 13 genomic species within the genus Gardnerella.Vaneechoutte M, Guschin A, Van Simaey L, Gansemans Y, Van Nieuwerburgh F, Cools PInt J Syst Evol Microbiol10.1099/ijsem.0.0032002019Bacterial Typing Techniques, Base Composition, DNA, Bacterial/genetics, Gardnerella/*classification, Gardnerella vaginalis/*classification, Nucleic Acid Hybridization, *Phylogeny, RNA, Ribosomal, 16S/genetics, Sequence Analysis, DNA, Spectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationTranscriptome
30728634Evaluation of Lactobacilli for Antagonistic Activity Against the Growth, Adhesion and Invasion of Klebsiella pneumoniae and Gardnerella vaginalis.Tsai CC, Lai TM, Hsieh YMIndian J Microbiol10.1007/s12088-018-0753-x2018
32867033Type II Restriction-Modification System from Gardnerella vaginalis ATCC 14018.Bulavaite A, Dalgediene I, Michailoviene V, Pleckaityte MPathogens10.3390/pathogens90907032020
Pathogenicity33680986Lactobacillus rhamnosus and Lactobacillus casei Affect Various Stages of Gardnerella Species Biofilm Formation.He Y, Na R, Niu X, Xiao B, Yang HFront Cell Infect Microbiol10.3389/fcimb.2021.5681782021Biofilms, Female, Gardnerella, Gardnerella vaginalis, Humans, *Lactobacillus casei, *Lactobacillus rhamnosus, *Probiotics, Vagina
Pathogenicity35440653Identification and characterization of novel endolysins targeting Gardnerella vaginalis biofilms to treat bacterial vaginosis.Arroyo-Moreno S, Cummings M, Corcoran DB, Coffey A, McCarthy RRNPJ Biofilms Microbiomes10.1038/s41522-022-00285-02022Biofilms, Dysbiosis, Endopeptidases, Escherichia coli, Female, Gardnerella vaginalis, Humans, Infant, Newborn, Pregnancy, *Premature Birth, *Vaginosis, Bacterial/drug therapy/microbiology

Reference

@idauthorscataloguedoi/urltitlejournalpubmed
1884Curators of the DSMZLeibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 4944)https://www.dsmz.de/collection/catalogue/details/culture/DSM-4944
20215Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.10.1099/ijsem.0.004332List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ
20218Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.10.1016/j.syapm.2013.11.002StrainInfo introduces electronic passports for microorganisms.Syst Appl Microbiol. 37: 42-50 201424321274
22917J. R. GREENWOOD, M. J. PICKETT10.1099/00207713-30-1-170Transfer of Haemophilus vaginalis Gardner and Dukes to a New Genus, Gardnerella: G. vaginalis (Gardner and Dukes) comb. novIJSEM 30: 170-178 1980
36208Curators of the CIPhttps://brclims.pasteur.fr/brcWeb/souche/detail/1/10550
44687Curators of the CCUGCulture Collection University of Gothenburg (CCUG) (CCUG 3717)https://www.ccug.se/strain?id=3717
66792Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmannhttps://diaspora-project.de/progress.html#genomesAutomatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)
67770Curators of the JCMhttps://jcm.brc.riken.jp/en/
68368Automatically annotated from API 20E
68376Automatically annotated from API LIST
68377Automatically annotated from API NH
68380Automatically annotated from API rID32A
68381Automatically annotated from API rID32STR
68382Automatically annotated from API zym
69479João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.https://microbeatlas.org/MicrobeAtlas 1.0 beta
69480Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmannhttps://diaspora-project.de/progress.html#genomesPredictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)
69481Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch10.21203/rs.3.rs-2527258/v1Predictions based on the model GenomeNet Sporulation v. 1
71404Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.10.60712/SI-ID92252.1StrainInfo: A central database for resolving microbial strain identifiers
123778Curators of the CIPCollection of Institut Pasteur (CIP 70.74)https://catalogue-crbip.pasteur.fr/fiche_catalogue.xhtml?crbip=CIP%2070.74