Archive BacDiveID:10.13145/bacdive1709.20230509.8.1

Strain identifier

BacDive ID: 1709

Type strain:

Species: Bifidobacterium longum

Strain Designation: E194b (Variant a), E194b

Strain history: CIP <- 1964, Lab. Ident. Inst. Pasteur, Paris, France <- M. Sebald, Inst. Pasteur, Paris, France <- H. Werner <- G. Reuter: strain E194b

NCBI tax ID(s): 565042 (strain), 216816 (species)

For citation purpose refer to the digital object identifier (doi) of the current version.

General

@ref: 8612

BacDive-ID: 1709

DSM-Number: 20219

keywords: genome sequence, 16S sequence, Bacteria, anaerobe, mesophilic, Gram-positive, rod-shaped

description: Bifidobacterium longum E194b is an anaerobe, mesophilic, Gram-positive bacterium that was isolated from intestine of adult.

NCBI tax id

NCBI tax id	Matching level
565042	strain
216816	species

strain history

@ref	history
8612	<- G. Reuter, E194b (Variant a)
67770	ATCC 15707 <-- G. Reuter E194b (Variant a).
120652	CIP <- 1964, Lab. Ident. Inst. Pasteur, Paris, France <- M. Sebald, Inst. Pasteur, Paris, France <- H. Werner <- G. Reuter: strain E194b

doi: 10.13145/bacdive1709.20230509.8.1

Name and taxonomic classification

LPSN

@ref: 20215
description: domain/bacteria
keyword: phylum/actinomycetota
domain: Bacteria
phylum: Actinomycetota
class: Actinomycetes
order: Bifidobacteriales
family: Bifidobacteriaceae
genus: Bifidobacterium
species: Bifidobacterium longum
full scientific name: Bifidobacterium longum Reuter 1963 (Approved Lists 1980)

@ref: 8612

domain: Bacteria

phylum: Actinobacteria

class: Actinobacteria

order: Bifidobacteriales

family: Bifidobacteriaceae

genus: Bifidobacterium

species: Bifidobacterium longum subsp. longum

full scientific name: Bifidobacterium longum subsp. longum (Reuter 1963) Mattarelli et al. 2008

strain designation: E194b (Variant a), E194b

type strain: yes

Morphology

cell morphology

@ref: 120652
gram stain: positive
cell shape: rod-shaped
motility: no

Culture and growth conditions

culture medium

@ref	name	growth	composition	link
38030	MEDIUM 20 - for Anaerobic bacteria	yes	Agar (15.000 g);Glucose (5.000 g);Yeast extract (20.000 g);Tryptone (30.000 g);Cysteine hydrochloride (0.500 g);distilled water (1000.000 ml);Hemin solution -M00149 (25.000 ml)
8612	BIFIDOBACTERIUM MEDIUM (DSMZ Medium 58)	yes	Name: BIFIDOBACTERIUM MEDIUM (DSMZ Medium 58) Composition: Glucose 10.0 g/l Casein peptone 10.0 g/l Bacto Soytone 5.0 g/l Meat extract 5.0 g/l Yeast extract 5.0 g/l L-Cysteine HCl x H2O 0.5 g/l NaHCO3 0.4 g/l NaCl 0.08 g/l MnSO4 x H2O 0.05 g/l KH2PO4 0.04 g/l K2HPO4 0.04 g/l MgSO4 x 7 H2O 0.02 g/l CaCl2 x 2 H2O 0.01 g/l Tween 80 Resazurin Distilled water	https://mediadive.dsmz.de/medium/58
120652	CIP Medium 20	yes		https://catalogue-crbip.pasteur.fr/fiche_milieu.xhtml?crbip=20

culture temp

@ref	growth	type	temperature	range
38030	positive	growth	37	mesophilic
49449	positive	growth	37	mesophilic
8612	positive	growth	37	mesophilic
67770	positive	growth	37	mesophilic

Physiology and metabolism

oxygen tolerance

@ref	oxygen tolerance
8612	anaerobe
49449	anaerobe
120652	facultative anaerobe

murein

@ref: 8612
murein short key: A21.03
type: A3ß L-Orn-L-Ser-L-Ala-L-Thr-L-Ala

metabolite utilization

@ref	metabolite	utilization activity	kind of utilization tested	Chebi-ID
68371	Potassium 2-ketogluconate	-	builds acid from
68371	gluconate	-	builds acid from	24265
68371	L-arabitol	-	builds acid from	18403
68371	D-arabitol	-	builds acid from	18333
68371	L-fucose	-	builds acid from	18287
68371	D-fucose	-	builds acid from	28847
68371	D-tagatose	-	builds acid from	16443
68371	D-lyxose	-	builds acid from	62318
68371	gentiobiose	-	builds acid from	28066
68371	xylitol	-	builds acid from	17151
68371	glycogen	-	builds acid from	28087
68371	raffinose	+	builds acid from	16634
68371	melezitose	+	builds acid from	6731
68371	melibiose	+	builds acid from	28053
68371	lactose	+	builds acid from	17716
68371	maltose	+	builds acid from	17306
68371	cellobiose	-	builds acid from	17057
68371	salicin	-	builds acid from	17814
68371	arbutin	-	builds acid from	18305
68371	amygdalin	-	builds acid from	27613
68371	N-acetylglucosamine	-	builds acid from	59640
68371	methyl alpha-D-glucopyranoside	+	builds acid from	320061
68371	D-sorbitol	-	builds acid from	17924
68371	D-mannitol	-	builds acid from	16899
68371	myo-inositol	-	builds acid from	17268
68371	galactitol	-	builds acid from	16813
68371	L-rhamnose	-	builds acid from	62345
68371	D-fructose	+	builds acid from	15824
68371	D-glucose	+	builds acid from	17634
68371	D-galactose	+	builds acid from	12936
68371	methyl beta-D-xylopyranoside	-	builds acid from	74863
68371	ribitol	-	builds acid from	15963
68371	L-xylose	-	builds acid from	65328
68371	D-xylose	+	builds acid from	65327
68371	D-ribose	+	builds acid from	16988
68371	L-arabinose	+	builds acid from	30849
68371	D-arabinose	-	builds acid from	17108
68371	erythritol	-	builds acid from	17113
68371	glycerol	-	builds acid from	17754
120652	nitrate	-	reduction	17632
120652	nitrite	-	reduction	16301

metabolite production

@ref: 120652
Chebi-ID: 35581
metabolite: indole
production: no

enzymes

@ref	value	activity	ec
68382	alpha-fucosidase	-	3.2.1.51
68382	alpha-mannosidase	-	3.2.1.24
68382	N-acetyl-beta-glucosaminidase	+	3.2.1.52
68382	beta-glucosidase	+	3.2.1.21
68382	alpha-glucosidase	+	3.2.1.20
68382	beta-glucuronidase	-	3.2.1.31
68382	beta-galactosidase	+	3.2.1.23
68382	alpha-galactosidase	+	3.2.1.22
68382	naphthol-AS-BI-phosphohydrolase	-
68382	acid phosphatase	+	3.1.3.2
68382	alpha-chymotrypsin	-	3.4.21.1
68382	trypsin	-	3.4.21.4
68382	cystine arylamidase	-	3.4.11.3
68382	valine arylamidase	-
68382	leucine arylamidase	+	3.4.11.1
68382	lipase (C 14)	-
68382	esterase lipase (C 8)	+
68382	esterase (C 4)	+
68382	alkaline phosphatase	-	3.1.3.1
120652	oxidase	-
120652	catalase	-	1.11.1.6
120652	urease	-	3.5.1.5

API zym

@ref	Control	Alkaline phosphatase	Esterase	Esterase Lipase	Lipase	Leucine arylamidase	Valine arylamidase	Cystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
120652	-	-	+	+	-	+	-	-	-	-	+	-	+	+	-	+	+	+	-	-

API 50CHac

@ref	Q	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
8612	-	-	-	-	+	+	+	-	-	-	+	+	+	-	-	-	-	-	-	-	-	+	-	-	-	+	-	-	+	+	+	+	-	-	+	+	-	-	-	-	+	-	-	-	-	-	-	-	-	-
8612	-	-	-	-	+	+	+	-	-	-	+	+	+	+	+	-	-	-	-	-	+/-	+	-	-	-	-	-	-	+	+	+	+	+	+	+	+	+/-	-	-	-	+/-	-	-	-	-	-	-	-	-	+/-
8612	-	-	-	-	+	+	+	-	-	-	+	+	+	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	+	+	+	+	-	-	+	+	-	-	-	-	+/-	-	-	-	-	-	-	-	-	-
8612	-	-	-	-	+	+	+	-	-	-	+	+	+	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	+	+	+	-	-	-	+	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-

Isolation, sampling and environmental information

isolation

@ref	sample type
8612	intestine of adult
49449	Human intestine,adult
67770	Intestine of adult
120652	Human, Intestine (adult)

isolation source categories

Cat1: #Host Body-Site
Cat2: #Gastrointestinal tract

taxonmaps

@ref: 69479
File name: preview.99_48.png
url: https://microbeatlas.org/index.html?action=taxon&taxon_id=90_24;96_39;97_41;98_45;99_48&stattab=map
Last taxonomy: Bifidobacterium longum subclade
16S sequence: LC071818
Sequence Identity:
Total samples: 207055
soil counts: 1795
aquatic counts: 7450
animal counts: 197025
plant counts: 785

Safety information

risk assessment

@ref	biosafety level	biosafety level comment
8612	1	Risk group (German classification)
120652	1	Risk group (French classification)

Sequence information

16S sequences

@ref	description	accession	length	database	NCBI tax ID
20218	Bifidobacterium longum strain ATCC 15707 16S ribosomal RNA gene, partial sequence	M58739	1476	ena	216816
20218	Bifidobacterium longum (ATCC 15707) 16S ribosomal RNA gene, partial	M84781	642	ena	216816
20218	Bifidobacterium longum subsp. longum strain DSM 20219 16S ribosomal RNA gene, partial sequence	HQ012022	940	ena	1679
20218	Bifidobacterium longum subsp. longum JCM 1217 gene for 16S rRNA, partial sequence	AB116313	476	ena	565042
20218	Bifidobacterium longum gene for 16S rRNA, partial sequence, strain: JCM 1217	AB507101	669	ena	565042
20218	Bifidobacterium longum subsp. longum strain KCTC 3128 16S ribosomal RNA gene, partial sequence	GU361823	1477	ena	1679
67770	Bifidobacterium longum subsp. longum gene for 16S ribosomal RNA, partial sequence	AB437359	1507	ena	1679
67770	Bifidobacterium longum subsp. longum gene for 16S ribosomal RNA, partial sequence, strain: JCM 1217	LC071818	1456	ena	1679

Genome sequences

@ref	description	accession	assembly level	database	NCBI tax ID
66792	Bifidobacterium longum NCTC11818	GCA_900637335	complete	ncbi	216816
66792	Bifidobacterium longum subsp. longum KCTC 3128	GCA_017132775	complete	ncbi	1679
66792	Bifidobacterium longum subsp. longum JCM 1217	GCA_000196555	complete	ncbi	565042
66792	Bifidobacterium longum strain DSM 20219	216816.128	wgs	patric	216816
66792	Bifidobacterium longum strain NCTC11818	216816.359	complete	patric	216816
66792	Bifidobacterium longum subsp. longum JCM 1217	565042.3	complete	patric	565042
66792	Bifidobacterium longum subsp. longum strain KCTC 3128	1679.291	complete	patric	1679
66792	Bifidobacterium longum subsp. longum strain LMG 13197	1679.6	wgs	patric	1679
66792	Bifidobacterium longum longum LMG 13197	2600254982	draft	img	1679
66792	Bifidobacterium longum longum DSM 20219	2634166334	draft	img	216816
66792	Bifidobacterium longum longum JCM 1217	649633019	complete	img	565042
67770	Bifidobacterium longum DSM 20219	GCA_900104835	contig	ncbi	216816
67770	Bifidobacterium longum subsp. longum LMG 13197	GCA_000741245	contig	ncbi	1679

GC content

@ref	GC-content	method
8612	61.4
67770	61.4	thermal denaturation, midpoint method (Tm)
67770	61.3	high performance liquid chromatography (HPLC)

Genome-based predictions

predictions

trait	prediction	confidence	training_data
motile	no	94.944	no
flagellated	no	97.197	no
gram-positive	yes	91.824	no
anaerobic	yes	98.353	no
aerobic	no	96.551	no
halophile	no	77.889	no
spore-forming	no	96.519	no
thermophile	no	95.572	yes
glucose-util	yes	87.063	no
glucose-ferment	yes	81.812	no

External links

@ref: 8612

culture collection no.: DSM 20219, ATCC 15707, NCTC 11818, CCUG 28903, LMG 13197, JCM 1217, LMG 10497, BCRC 11847, CECT 4503, CIP 64.62, KCTC 3128, KCTC 3215, NCFB 2259, VTT E-96664, NCDO 2259, WDCM 00225

straininfo link

@ref: 71356
straininfo: 376921

literature

topic	Pubmed-ID	title	authors	journal	DOI	year	mesh	topic2
Pathogenicity	1808458	Quantitative fluorometric assay for rapid enzymatic characterization of Bifidobacterium longum and related bifidobacteria.	O'Brien M, Mitsuoka T	Microbiol Immunol	10.1111/j.1348-0421.1991.tb01626.x	1991	Adolescent, Adult, Bifidobacterium/enzymology, Feces/microbiology, Fluorometry/methods, Humans, Hymecromone, Infant, Substrate Specificity	Enzymology
	3410989	Preparation of the bifidus milk powder.	Nagawa M, Nakabayashi A, Fujino S	J Dairy Sci	10.3168/jds.S0022-0302(88)79745-3	1988	Animals, Bifidobacterium, Milk/microbiology, Powders
Enzymology	7745146	Viability and enzymatic activity of bifidobacteria in milk.	Hughes DB, Hoover DG	J Dairy Sci	10.3168/jds.S0022-0302(95)76634-6	1995	Animals, Bifidobacterium/enzymology/growth & development, Cold Temperature, Freezing, Milk/microbiology, alpha-Galactosidase/metabolism	Metabolism
Genetics	7754230	Selection of species-specific DNA probes which detect strain restriction polymorphism in four Bifidobacterium species.	Mangin I, Bourget N, Simonet JM, Decaris B	Res Microbiol	10.1016/0923-2508(96)80271-3	1995	Base Sequence, Bifidobacterium/genetics, Blotting, Southern, DNA, Bacterial/genetics, Genomic Library, In Vitro Techniques, Molecular Sequence Data, Nucleic Acid Hybridization, Open Reading Frames/genetics, Polymorphism, Restriction Fragment Length	Phylogeny
Cultivation	7763698	Effect of chelatants on gellan gel rheological properties and setting temperature for immobilization of living bifidobacteria.	Camelin I, Lacroix C, Paquin C, Prevost H, Cachon R, Divies C	Biotechnol Prog	10.1021/bp00021a008	1993	Bifidobacterium, Cell Movement, Chelating Agents, Culture Media, Gels, Hydrogen-Ion Concentration, Polysaccharides, Bacterial/chemistry, Rheology, Temperature
Metabolism	9145444	Investigations of bifidobacterial ecology and oligosaccharide metabolism in a three-stage compound continuous culture system.	McBain AJ, Macfarlane GT	Scand J Gastroenterol Suppl	10.1080/00365521.1997.11720715	1997	Arylsulfatases/metabolism, Bacteriological Techniques, Bifidobacterium/growth & development/metabolism, Colon/metabolism/microbiology, Ecosystem, Fermentation, Gastrointestinal Transit, Glucuronidase/metabolism, Humans, NADH, NADPH Oxidoreductases/metabolism, Nitroreductases/metabolism, Oligosaccharides/*metabolism, beta-Glucosidase/metabolism	Pathogenicity
Cultivation	10653768	Survival of Bifidobacterium longum immobilized in calcium alginate beads in simulated gastric juices and bile salt solution.	Lee KY, Heo TR	Appl Environ Microbiol	10.1128/AEM.66.2.869-873.2000	2000	Alginates, Bifidobacterium/growth & development, Bile Acids and Salts/pharmacology, Cells, Immobilized, Colony Count, Microbial, Culture Media, Gastric Juice/microbiology, Glucuronic Acid, Hexuronic Acids, Microspheres, Models, Biological
Metabolism	11286405	Formulations and processing of yogurt affect the microbial quality of carbonated yogurt.	Karagul-Yuceer Y, Wilson JC, White CH	J Dairy Sci	10.3168/jds.S0022-0302(01)74506-7	2001	Bacillus/growth & development/metabolism, Bacteria/growth & development/metabolism, Bifidobacterium/growth & development/metabolism, Carbon Dioxide, Colony Count, Microbial, Escherichia coli/growth & development/metabolism, Fermentation, Food Handling, Food Microbiology, Hydrogen-Ion Concentration, Lactobacillus/growth & development/metabolism, Listeria monocytogenes/growth & development/metabolism, Streptococcus/growth & development/metabolism, Taste, Temperature, Time Factors, Yogurt/analysis/microbiology	Biotechnology
Enzymology	12005055	Cloning and expression in Escherichia coli of a gene, hup, encoding the histone-like protein HU of Bifidobacterium longum.	Takeuchi A, Matsumura H, Kano Y	Biosci Biotechnol Biochem	10.1271/bbb.66.598	2002	Amino Acid Sequence, Bacterial Proteins/biosynthesis/genetics, Bacteriophage mu/genetics, Base Sequence, Bifidobacterium/genetics, Cloning, Molecular, DNA, Bacterial/biosynthesis/genetics, DNA-Binding Proteins/biosynthesis/genetics, Electroporation, Escherichia coli/metabolism, Gene Expression Regulation, Bacterial/genetics, Genes, Bacterial/*genetics, Molecular Sequence Data, Plasmids/genetics	Genetics
	12111161	Quantitative determination of the spatial distribution of pure- and mixed-strain immobilized cells in gel beads by immunofluorescence.	Doleyres Y, Fliss I, Lacroix C	Appl Microbiol Biotechnol	10.1007/s00253-002-1004-x	2002	Bifidobacterium/growth & development, Biomass, Cells, Immobilized, Enzyme-Linked Immunosorbent Assay, Fermentation, Fluorescent Antibody Technique, Lactobacillus/growth & development
Metabolism	12382059	Bifidobacterium longum ATCC 15707 cell production during free- and immobilized-cell cultures in MRS-whey permeate medium.	Doleyres Y, Paquin C, LeRoy M, Lacroix C	Appl Microbiol Biotechnol	10.1007/s00253-002-1103-8	2002	Bifidobacterium/growth & development/metabolism, Biomass, Cells, Immobilized, Culture Media/metabolism, Fermentation, Hydrogen-Ion Concentration, Milk Proteins/metabolism, Whey Proteins	Biotechnology
Metabolism	14763837	Continuous production of mixed lactic starters containing probiotics using immobilized cell technology.	Doleyres Y, Fliss I, Lacroix C	Biotechnol Prog	10.1021/bp020096w	2004	Bacterial Adhesion/physiology, Bifidobacterium/cytology/growth & development/metabolism, Bioreactors/microbiology, Carbohydrate Metabolism, Cell Division, Cell Survival/physiology, Cells, Immobilized/physiology, Coculture Techniques/methods, Lactic Acid/metabolism, Lactococcus lactis/cytology/growth & development/*metabolism, Species Specificity, Temperature	Phylogeny
Pathogenicity	15281933	Increased stress tolerance of Bifidobacterium longum and Lactococcus lactis produced during continuous mixed-strain immobilized-cell fermentation.	Doleyres Y, Fliss I, Lacroix C	J Appl Microbiol	10.1111/j.1365-2672.2004.02326.x	2004	Anti-Bacterial Agents/pharmacology, Bifidobacterium/drug effects/physiology, Cells, Immobilized, Chloramphenicol/pharmacology, Colony Count, Microbial, Culture Media, Drug Resistance, Microbial, Duodenum/microbiology, Fermentation/physiology, Food Microbiology, Freeze Drying/methods, Gastric Juice/physiology, Hydrogen Peroxide/metabolism, Lactococcus lactis/drug effects/physiology, Nisin/*analogs & derivatives/pharmacology, Probiotics	Cultivation
Metabolism	15662546	Fermentation of a milk-soymilk and Lycium chinense Miller mixture using a new isolate of Lactobacillus paracasei subsp. paracasei NTU101 and Bifidobacterium longum.	Lin FM, Chiu CH, Pan TM	J Ind Microbiol Biotechnol	10.1007/s10295-004-0184-z	2004	Animals, Bifidobacterium/metabolism, Colony Count, Microbial, Culture Media, Fermentation, Food Microbiology, Hydrogen-Ion Concentration, Industrial Microbiology/methods, Lactobacillus/metabolism, Lycium/metabolism/microbiology, Milk/metabolism/microbiology, Probiotics, Soy Milk/metabolism	Biotechnology
Metabolism	15747118	Kinetics of Bifidobacterium longum ATCC 15707 fermentations: effect of the dilution rate and carbon source.	Shene C, Mardones M, Zamora P, Bravo S	Appl Microbiol Biotechnol	10.1007/s00253-004-1792-2	2005	Acetic Acid/metabolism, Bacterial Proteins/analysis, Bifidobacterium/metabolism, Biomass, Fermentation, Formates/metabolism, Fructose/metabolism, Glucose/metabolism, Kinetics, Lactic Acid/metabolism, Mathematics, Models, Biological, Oligosaccharides/metabolism	Enzymology
Metabolism	15862361	Optimization of a Bifidobacterium longum production process.	Kiviharju K, Leisola M, Eerikainen T	J Biotechnol	10.1016/j.jbiotec.2005.02.007	2005	Bifidobacterium/cytology/growth & development/metabolism, Bioreactors/microbiology, Biotechnology/*methods, Cell Culture Techniques, Culture Media/chemistry, Cysteine/metabolism, Desiccation, Fermentation, Freeze Drying, Glucose/analysis, Probiotics/metabolism, Temperature, Time Factors	Biotechnology
Metabolism	15933016	Novel putative galactose operon involving lacto-N-biose phosphorylase in Bifidobacterium longum.	Kitaoka M, Tian J, Nishimoto M	Appl Environ Microbiol	10.1128/AEM.71.6.3158-3162.2005	2005	Acetylglucosamine/analogs & derivatives/metabolism, Amino Acid Sequence, Animals, Bacterial Proteins/genetics/metabolism, Bifidobacterium/enzymology/genetics, Cloning, Molecular, Galactose/metabolism, Milk/chemistry, Operon, Pantetheine/analogs & derivatives/chemistry/metabolism, Phosphorylases/chemistry/genetics/isolation & purification/*metabolism, Sequence Alignment, Substrate Specificity	Enzymology
Enzymology	16141207	Identification and molecular cloning of a novel glycoside hydrolase family of core 1 type O-glycan-specific endo-alpha-N-acetylgalactosaminidase from Bifidobacterium longum.	Fujita K, Oura F, Nagamine N, Katayama T, Hiratake J, Sakata K, Kumagai H, Yamamoto K	J Biol Chem	10.1074/jbc.M506874200	2005	Amino Acid Sequence, Bifidobacterium/classification/enzymology/genetics, Cloning, Molecular, Glycosylation, Hydrolysis, Molecular Sequence Data, Multigene Family, Phylogeny, Substrate Specificity, alpha-N-Acetylgalactosaminidase/chemistry/genetics/metabolism	Phylogeny
Metabolism	17720833	Identification of N-acetylhexosamine 1-kinase in the complete lacto-N-biose I/galacto-N-biose metabolic pathway in Bifidobacterium longum.	Nishimoto M, Kitaoka M	Appl Environ Microbiol	10.1128/AEM.01425-07	2007	Acetylglucosamine/analogs & derivatives/metabolism, Bacterial Proteins/genetics/metabolism, Bifidobacterium/enzymology/genetics, Disaccharides/metabolism, Escherichia coli/enzymology/genetics, Hexosamines/metabolism, Molecular Sequence Data, Operon, Phosphotransferases/*metabolism, Sequence Analysis, DNA	Enzymology
Enzymology	17768345	Purification, crystallization and preliminary X-ray analysis of the galacto-N-biose-/lacto-N-biose I-binding protein (GL-BP) of the ABC transporter from Bifidobacterium longum JCM1217.	Wada J, Suzuki R, Fushinobu S, Kitaoka M, Wakagi T, Shoun H, Ashida H, Kumagai H, Katayama T, Yamamoto K	Acta Crystallogr Sect F Struct Biol Cryst Commun	10.1107/S1744309107036263	2007	ATP-Binding Cassette Transporters/chemistry/isolation & purification, Bacterial Proteins/chemistry/isolation & purification, Bifidobacterium/chemistry, Crystallization, DNA Primers, Plasmids, Recombinant Proteins/chemistry/isolation & purification, X-Ray Diffraction	Phylogeny
Enzymology	18183385	Identification of galacto-N-biose phosphorylase from Clostridium perfringens ATCC13124.	Nakajima M, Nihira T, Nishimoto M, Kitaoka M	Appl Microbiol Biotechnol	10.1007/s00253-007-1319-8	2008	Bacterial Proteins/genetics/metabolism, Base Sequence, Bifidobacterium/enzymology, Cloning, Molecular, Clostridium perfringens/enzymology/metabolism, Codon, Initiator/analysis, Enzyme Stability, Galactose/metabolism, Humans, Kinetics, Phosphorylases/chemistry/genetics/isolation & purification/metabolism, Phosphorylation, Recombinant Proteins/genetics/metabolism, Substrate Specificity	Metabolism
Phylogeny	18398167	Proposal to reclassify the three biotypes of Bifidobacterium longum as three subspecies: Bifidobacterium longum subsp. longum subsp. nov., Bifidobacterium longum subsp. infantis comb. nov. and Bifidobacterium longum subsp. suis comb. nov.	Mattarelli P, Bonaparte C, Pot B, Biavati B	Int J Syst Evol Microbiol	10.1099/ijs.0.65319-0	2008	Bacterial Proteins/genetics, Bacterial Typing Techniques, Bifidobacterium/classification/genetics/metabolism, Carbohydrate Metabolism, Chaperonin 60/genetics, DNA, Bacterial/genetics, Fermentation, Genes, Bacterial, Genotype, Nucleic Acid Hybridization, Phenotype, Plasmids/genetics, Polymerase Chain Reaction, RNA, Bacterial/genetics, RNA, Ribosomal, 16S/genetics, Ribotyping, Species Specificity, Terminology as Topic	Metabolism
Pathogenicity	18539808	Differential transcriptional response of Bifidobacterium longum to human milk, formula milk, and galactooligosaccharide.	Gonzalez R, Klaassens ES, Malinen E, de Vos WM, Vaughan EE	Appl Environ Microbiol	10.1128/AEM.00122-08	2008	Bifidobacterium/drug effects/genetics/growth & development, Culture Media, DNA, Bacterial/genetics, Female, Galactose, Humans, Infant Food/microbiology, Milk, Human/microbiology, Oligonucleotide Array Sequence Analysis, Oligosaccharides/pharmacology, RNA, Bacterial/genetics/isolation & purification, *Transcription, Genetic/drug effects	Cultivation
Pathogenicity	18614524	Analysis of tetracycline resistance tet(W) genes and their flanking sequences in intestinal Bifidobacterium species.	Ammor MS, Florez AB, Alvarez-Martin P, Margolles A, Mayo B	J Antimicrob Chemother	10.1093/jac/dkn280	2008	Anti-Bacterial Agents/pharmacology, Bacterial Proteins/genetics, Bifidobacterium/genetics/isolation & purification, DNA Transposable Elements, DNA, Bacterial/chemistry/genetics, Gastrointestinal Tract/microbiology, Humans, Molecular Sequence Data, Mutagenesis, Insertional, Recombination, Genetic, Sequence Analysis, DNA, Sequence Homology, Amino Acid, Sequence Homology, Nucleic Acid, Tetracycline/pharmacology, *Tetracycline Resistance	Genetics
Metabolism	19502354	Crystallographic and mutational analyses of substrate recognition of endo-alpha-N-acetylgalactosaminidase from Bifidobacterium longum.	Suzuki R, Katayama T, Kitaoka M, Kumagai H, Wakagi T, Shoun H, Ashida H, Yamamoto K, Fushinobu S	J Biochem	10.1093/jb/mvp086	2009	Amino Acid Sequence, Bacterial Proteins/chemistry/genetics/metabolism, Bifidobacterium/enzymology, Biocatalysis, Catalytic Domain, Crystallography, X-Ray, Disaccharides/metabolism, Enzyme Stability, Gram-Positive Bacteria/enzymology, Kinetics, Ligands, Metals/chemistry, Models, Molecular, Molecular Sequence Data, Mutagenesis, Site-Directed, Mutant Proteins/chemistry/metabolism, Polysaccharides/metabolism, Protein Binding, Protein Structure, Tertiary, Recombinant Fusion Proteins/chemistry/metabolism, Sequence Alignment, Substrate Specificity, alpha-N-Acetylgalactosaminidase/chemistry/genetics/*metabolism	Enzymology
Metabolism	19694435	In vitro fermentation of arabinoxylan-derived carbohydrates by bifidobacteria and mixed fecal microbiota.	Pastell H, Westermann P, Meyer AS, Tuomainen P, Tenkanen M	J Agric Food Chem	10.1021/jf901397b	2009	Arabinose/metabolism, Bifidobacterium/genetics/growth & development/metabolism, DNA, Bacterial/analysis, Feces/microbiology, Fermentation, Humans, Hydrogen-Ion Concentration, Oligosaccharides/metabolism, Species Specificity, Xylans/*metabolism, Xylose/metabolism	Pathogenicity
Pathogenicity	19763042	The screening method of a bifidogenic dietary fiber extracted from inedible parts of vegetables.	Iwata E, Hotta H, Goto M	J Nutr Sci Vitaminol (Tokyo)	10.3177/jnsv.55.385	2009	Animals, Bacteria/drug effects/growth & development, Bifidobacterium/drug effects/growth & development, Cecum/microbiology, Colony Count, Microbial, Dietary Fiber/pharmacology, Feces/microbiology, Fermentation, Fruit, Humans, Magnoliopsida/chemistry, Peas/chemistry, Prebiotics, Rats, Vegetables
Metabolism	19845481	Development of silk fibroin-based beads for immobilized cell fermentations.	Yildirim S, Borer ME, Wenk E, Meinel L, Lacroix C	J Microencapsul	10.3109/02652040802217516	2010	Animals, Bifidobacterium/cytology/metabolism, Bombyx/chemistry, Cells, Immobilized/cytology/metabolism, Fermentation, Fibroins/chemistry/isolation & purification, Silk/chemistry/isolation & purification	Enzymology
Pathogenicity	20007908	Pivotal Advance: Bifidobacteria and Gram-negative bacteria differentially influence immune responses in the proinflammatory milieu of celiac disease.	De Palma G, Cinova J, Stepankova R, Tuckova L, Sanz Y	J Leukoc Biol	10.1189/jlb.0709471	2009	Bifidobacterium/immunology, Caco-2 Cells, Celiac Disease/immunology/microbiology, Cell Separation, Coculture Techniques, Cytokines/biosynthesis, Flow Cytometry, Gram-Negative Bacteria/immunology, Humans, Intestinal Mucosa/immunology/microbiology, Leukocytes, Mononuclear/*immunology
Enzymology	21149454	Molecular cloning and characterization of a beta-L-Arabinobiosidase in Bifidobacterium longum that belongs to a novel glycoside hydrolase family.	Fujita K, Sakamoto S, Ono Y, Wakao M, Suda Y, Kitahara K, Suganuma T	J Biol Chem	10.1074/jbc.M110.190512	2010	Amino Acid Sequence, Arabinose/analogs & derivatives/chemistry/metabolism, Bacterial Proteins/chemistry/genetics/metabolism, Bifidobacterium/enzymology/genetics, Cloning, Molecular, Glycoside Hydrolases/*chemistry/genetics/metabolism, Molecular Sequence Data, Xanthomonas/enzymology/genetics	Metabolism
Metabolism	21832085	Physiology of consumption of human milk oligosaccharides by infant gut-associated bifidobacteria.	Asakuma S, Hatakeyama E, Urashima T, Yoshida E, Katayama T, Yamamoto K, Kumagai H, Ashida H, Hirose J, Kitaoka M	J Biol Chem	10.1074/jbc.M111.248138	2011	Adult, Bifidobacteriales Infections/microbiology, Bifidobacterium/metabolism, Carbohydrates/chemistry, Chromatography, High Pressure Liquid/methods, Female, Gastrointestinal Tract/microbiology, Humans, Infant, Newborn, Intestines/microbiology, Japan, Milk, Human/metabolism, Molecular Sequence Data, Monosaccharides, Oligosaccharides/chemistry/metabolism, Time Factors	Pathogenicity
Enzymology	21914802	Characterization of a novel beta-L-Arabinofuranosidase in Bifidobacterium longum: functional elucidation of A DUF1680 family member.	Fujita K, Takashi Y, Obuchi E, Kitahara K, Suganuma T	J Biol Chem	10.1074/jbc.M111.248690	2011	Bifidobacterium/enzymology, Chromatography, High Pressure Liquid, Fermentation, Glycoside Hydrolases/chemistry, Glycosylation, Hydrolysis, Kinetics, Models, Chemical, Molecular Sequence Data, Mutagenesis, Site-Directed, Oligosaccharides/chemistry, Polymers/chemistry, Substrate Specificity, Temperature, Time Factors	Genetics
Pathogenicity	23010308	Bifidobacterium spp. influences the production of autoinducer-2 and biofilm formation by Escherichia coli O157:H7.	Kim Y, Lee JW, Kang SG, Oh S, Griffiths MW	Anaerobe	10.1016/j.anaerobe.2012.08.006	2012	Adult, Animals, Anti-Bacterial Agents/isolation & purification/pharmacology, Bifidobacterium/chemistry, Biofilms/growth & development, Caenorhabditis elegans/microbiology, Disease Models, Animal, Escherichia coli Infections/microbiology, Escherichia coli O157/chemistry/drug effects/pathogenicity/physiology, Escherichia coli Proteins/analysis, Homoserine/analogs & derivatives/metabolism, Humans, Infant, Lactones/metabolism, Microbial Interactions, Proteome/analysis, Survival Analysis, Vibrio/growth & development/metabolism/physiology	Metabolism
Metabolism	23332852	Antimicrobial potential for the combination of bovine lactoferrin or its hydrolysate with lactoferrin-resistant probiotics against foodborne pathogens.	Chen PW, Jheng TT, Shyu CL, Mao FC	J Dairy Sci	10.3168/jds.2012-6112	2013	Animals, Anti-Infective Agents/administration & dosage/therapeutic use, Bifidobacterium/metabolism, Cattle, Enterococcus faecalis/drug effects, Escherichia coli/drug effects, Lactobacillus/metabolism, Lactobacillus acidophilus/metabolism, Lactobacillus rhamnosus/metabolism, Lactoferrin/administration & dosage/drug effects/therapeutic use, Pediococcus/metabolism, Probiotics/administration & dosage/*therapeutic use, Protein Hydrolysates, Salmonella typhimurium/drug effects	Pathogenicity
Metabolism	23843461	Lacto-N-biosidase encoded by a novel gene of Bifidobacterium longum subspecies longum shows unique substrate specificity and requires a designated chaperone for its active expression.	Sakurama H, Kiyohara M, Wada J, Honda Y, Yamaguchi M, Fukiya S, Yokota A, Ashida H, Kumagai H, Kitaoka M, Yamamoto K, Katayama T	J Biol Chem	10.1074/jbc.M113.484733	2013	Bacterial Proteins/chemistry/genetics/metabolism, Bifidobacterium/enzymology/genetics, Calcium/chemistry/metabolism, Genes, Bacterial/physiology, Glycoside Hydrolases/chemistry/genetics/metabolism, Humans, Infant, Magnesium/chemistry/metabolism, Oligosaccharides/chemistry/genetics/metabolism, Substrate Specificity	Pathogenicity
Metabolism	24072764	Synergistic antibacterial efficacies of the combination of bovine lactoferrin or its hydrolysate with probiotic secretion in curbing the growth of meticillin-resistant Staphylococcus aureus.	Chen PW, Jheng TT, Shyu CL, Mao FC	J Med Microbiol	10.1099/jmm.0.052639-0	2013	Animals, Anti-Bacterial Agents/metabolism, Bifidobacterium/metabolism, Cattle, Humans, Lactobacillus fermentum/metabolism, Lactoferrin/metabolism, Methicillin-Resistant Staphylococcus aureus/immunology, Microbial Sensitivity Tests/methods, Probiotics/metabolism, Protein Hydrolysates/*metabolism, Staphylococcal Infections/metabolism	Pathogenicity
Metabolism	24385433	Characterization of a novel beta-L-arabinofuranosidase in Bifidobacterium longum: functional elucidation of a DUF1680 protein family member.	Fujita K, Takashi Y, Obuchi E, Kitahara K, Suganuma T	J Biol Chem	10.1074/jbc.M113.528711	2014	Amino Acids/metabolism, Arabinose/analogs & derivatives/chemistry/metabolism, Bacterial Proteins/chemistry/isolation & purification/metabolism, Bifidobacterium/enzymology/growth & development, Chromatography, High Pressure Liquid, Chromatography, Ion Exchange, Chromatography, Thin Layer, Electrophoresis, Polyacrylamide Gel, Fermentation, Glycoproteins/metabolism, Glycoside Hydrolases/chemistry/metabolism, Glycosylation, Hydrogen-Ion Concentration, Kinetics, Magnetic Resonance Spectroscopy, Models, Biological, Molecular Sequence Data, Mutagenesis, Site-Directed, Mutant Proteins/metabolism, Recombinant Proteins/metabolism, Sequence Analysis, Protein, Substrate Specificity, Temperature	Enzymology
Metabolism	24816108	Insights into the binding specificity and catalytic mechanism of N-acetylhexosamine 1-phosphate kinases through multiple reaction complexes.	Wang KC, Lyu SY, Liu YC, Chang CY, Wu CJ, Li TL	Acta Crystallogr D Biol Crystallogr	10.1107/S1399004714004209	2014	Acetylglucosamine/metabolism, Adenosine Diphosphate/metabolism, Adenosine Triphosphate/metabolism, Bifidobacterium/enzymology/metabolism, Binding Sites, Crystallography, X-Ray, Magnesium/metabolism, Models, Molecular, Mutagenesis, Site-Directed, Phosphotransferases/chemistry/genetics/*metabolism, Protein Conformation, Substrate Specificity	Enzymology
Enzymology	24817727	Crystallization and preliminary X-ray diffraction analysis of a novel beta-L-arabinofuranosidase (HypBA1) from Bifidobacterium longum.	Zhu Z, He M, Huang CH, Ko TP, Zeng YF, Huang YN, Jia S, Lu F, Liu JR, Guo RT	Acta Crystallogr F Struct Biol Commun	10.1107/S2053230X14001812	2014	Bifidobacterium/enzymology, Crystallization, Glycoside Hydrolases/chemistry/*isolation & purification, X-Ray Diffraction	Phylogeny
Enzymology	24837371	Bifidobacterium longum subsp. longum Exo-beta-1,3-Galactanase, an enzyme for the degradation of type II arabinogalactan.	Fujita K, Sakaguchi T, Sakamoto A, Shimokawa M, Kitahara K	Appl Environ Microbiol	10.1128/AEM.00802-14	2014	Bacterial Proteins/chemistry/genetics/metabolism, Bifidobacterium/chemistry/classification/enzymology/genetics, Cloning, Molecular, Enzyme Stability, Galactans/metabolism, Glycoside Hydrolases/chemistry/genetics/metabolism, Kinetics, Molecular Sequence Data, Phylogeny, Protein Structure, Tertiary, Substrate Specificity	Metabolism
	24936358	Effects of Enteric-coated Lactoferrin Tablets Containing Lactobacillus brevis subsp. coagulans on Fecal Properties, Defecation Frequency and Intestinal Microbiota of Japanese Women with a Tendency for Constipation: a Randomized Placebo-controlled Crossover Study.	Suzuki N, Murakoshi M, Ono T, Morishita S, Koide M, Bae MJ, Totsuka M, Shimizu M, Sugiyama K, Nishino H, Iida N	Biosci Microbiota Food Health	10.12938/bmfh.32.13	2013
Stress	25729438	Cocktails of probiotics pre-adapted to multiple stress factors are more robust under simulated gastrointestinal conditions than their parental counterparts and exhibit enhanced antagonistic capabilities against Escherichia coli and Staphylococcus aureus.	Mathipa MG, Thantsha MS	Gut Pathog	10.1186/s13099-015-0053-5	2015
	26458011	Lyophilised Vegetal BM 297 ATO-Inulin lipid-based synbiotic microparticles containing Bifidobacterium longum LMG 13197: design and characterisation.	Amakiri AC, Kalombo L, Thantsha MS	J Microencapsul	10.3109/02652048.2015.1094534	2015	Bifidobacterium/chemistry, Diglycerides/chemistry, Freeze Drying, Inulin/chemistry, Porosity, Symbiosis
Pathogenicity	26486646	Membrane filter method to study the effects of Lactobacillus acidophilus and Bifidobacterium longum on fecal microbiota.	Shimizu H, Benno Y	Microbiol Immunol	10.1111/1348-0421.12332	2015	Bifidobacterium/physiology, Clostridium/growth & development/physiology, Coculture Techniques/methods, Gastrointestinal Microbiome, Humans, Lactobacillus acidophilus/physiology, Ruminococcus/growth & development/physiology, Streptococcus/growth & development/physiology, Veillonella/growth & development/*physiology
	27588236	Survival of Bifidobacterium longum LMG 13197 microencapsulated in Vegetal or Vegetal-inulin matrix in simulated gastrointestinal fluids and yoghurt.	Amakiri AC, Thantsha MS	Springerplus	10.1186/s40064-016-3010-y	2016
Enzymology	28283459	Characterization of novel thermophilic alpha-glucosidase from Bifidobacterium longum.	Kim NR, Jeong DW, Ko DS, Shim JH	Int J Biol Macromol	10.1016/j.ijbiomac.2017.03.009	2017	Bifidobacterium longum/enzymology/genetics, Cloning, Molecular, Enzyme Stability, Hydrogen-Ion Concentration, Kinetics, Metals/pharmacology, Recombinant Proteins/chemistry/genetics/isolation & purification/metabolism, Temperature, alpha-Glucosidases/chemistry/genetics/isolation & purification/metabolism	Phylogeny
	28437455	Effect of a probiotic beverage consumption (Enterococcus faecium CRL 183 and Bifidobacterium longum ATCC 15707) in rats with chemically induced colitis.	Celiberto LS, Bedani R, Dejani NN, Ivo de Medeiros A, Sampaio Zuanon JA, Spolidorio LC, Tallarico Adorno MA, Amancio Varesche MB, Carrilho Galvao F, Valentini SR, Font de Valdez G, Rossi EA, Cavallini DCU	PLoS One	10.1371/journal.pone.0175935	2017	Animals, Beverages, Bifidobacterium longum, Colitis/chemically induced/drug therapy/microbiology, Dextran Sulfate, Disease Models, Animal, Enterococcus faecium, Fatty Acids, Volatile/analysis, Feces/chemistry/microbiology, Intestines/microbiology, Probiotics/therapeutic use, Rats, Treatment Outcome
	28747822	Beneficial Effect of Bifidobacterium longum ATCC 15707 on Survival Rate of Clostridium difficile Infection in Mice.	Yun B, Song M, Park DJ, Oh S	Korean J Food Sci Anim Resour	10.5851/kosfa.2017.37.3.368	2017
	28763015	Effect of Non-Dairy Food Matrices on the Survival of Probiotic Bacteria during Storage.	Min M, Bunt CR, Mason SL, Bennett GN, Hussain MA	Microorganisms	10.3390/microorganisms5030043	2017
Enzymology	29380264	Expression and Characterization of Recombinant Sucrose Phosphorylase.	Zhang H, Sun X, Li W, Li T, Li S, Kitaoka M	Protein J	10.1007/s10930-017-9754-6	2018	Bacterial Proteins/biosynthesis/genetics, Bifidobacterium longum/enzymology/genetics, Escherichia coli/genetics/metabolism, Gene Expression, Glucosyltransferases/biosynthesis/genetics, Recombinant Proteins/biosynthesis/genetics	Metabolism
Metabolism	29914471	How accurate is automated gap filling of metabolic models?	Karp PD, Weaver D, Latendresse M	BMC Syst Biol	10.1186/s12918-018-0593-7	2018	Algorithms, Automation, Bifidobacterium longum/metabolism, Biomass, Metabolism, Models, Biological
Metabolism	30564851	Degradative enzymes for type II arabinogalactan side chains in Bifidobacterium longum subsp. longum.	Fujita K, Sakamoto A, Kaneko S, Kotake T, Tsumuraya Y, Kitahara K	Appl Microbiol Biotechnol	10.1007/s00253-018-9566-4	2018	Bifidobacterium longum/enzymology/genetics/metabolism, Galactans/metabolism, Gastrointestinal Microbiome/genetics, Gastrointestinal Tract/microbiology, Glycoside Hydrolases/genetics/metabolism, Humans, Recombinant Proteins/genetics/metabolism, beta-Galactosidase/*genetics/metabolism	Enzymology
Metabolism	30635377	Two Novel alpha-l-Arabinofuranosidases from Bifidobacterium longum subsp. longum Belonging to Glycoside Hydrolase Family 43 Cooperatively Degrade Arabinan.	Komeno M, Hayamizu H, Fujita K, Ashida H	Appl Environ Microbiol	10.1128/AEM.02582-18	2019	Amino Acid Sequence, Bacterial Proteins/chemistry/genetics/metabolism, Bifidobacterium longum/chemistry/enzymology/genetics/growth & development, Cloning, Molecular, Glycoside Hydrolases/chemistry/genetics/metabolism, Multigene Family, Polysaccharides/metabolism, Sequence Alignment, Substrate Specificity	Enzymology
Metabolism	31040837	Efficient Phytase Secretion and Phytate Degradation by Recombinant Bifidobacterium longum JCM 1217.	Sun Z, Yue Z, Yang X, Hao X, Song M, Li L, Chen C, Chu C, Li C	Front Microbiol	10.3389/fmicb.2019.00796	2019
Biotechnology	31733264	Viability assessment of Bifidobacterium longum ATCC 15707 on non-dairy foods using quantitative fluorescence microscopy.	Min M, Mason SL, Bennett GN, Hussain MA, Bunt CR	J Microbiol Methods	10.1016/j.mimet.2019.105778	2019	Bifidobacterium longum/growth & development, Centrifugation, Density Gradient/methods, Colony Count, Microbial/methods, Food Microbiology/methods, Microbial Viability, Microscopy, Fluorescence/methods, Povidone, Silicon Dioxide, Staining and Labeling/methods
Pathogenicity	32114169	Rheological properties of a neutral polysaccharide extracted from maca (Lepidium meyenii Walp.) roots with prebiotic and anti-inflammatory activities.	Lee YK, Jung SK, Chang YH	Int J Biol Macromol	10.1016/j.ijbiomac.2020.02.307	2020	Animals, Anti-Inflammatory Agents/chemistry, Cell Line, Hydrogen Bonding, Lepidium/chemistry, Mice, Molecular Weight, Plant Extracts/chemistry, Plant Roots/chemistry, Polysaccharides/*chemistry, Prebiotics, RAW 264.7 Cells, Rheology/methods, Viscosity/drug effects
	32419965	Properties of recombinant 4-alpha-glucanotransferase from Bifidobacterium longum subsp. longum JCM 1217 and its application.	Jeong DW, Jeong HM, Shin YJ, Woo SH, Shim JH	Food Sci Biotechnol	10.1007/s10068-019-00707-4	2019
Enzymology	32479540	Crystal structure of beta-L-arabinobiosidase belonging to glycoside hydrolase family 121.	Saito K, Viborg AH, Sakamoto S, Arakawa T, Yamada C, Fujita K, Fushinobu S	PLoS One	10.1371/journal.pone.0231513	2020	Amino Acid Sequence, Bifidobacterium longum/enzymology, Catalytic Domain, Crystallography, X-Ray, Glycoside Hydrolases/*chemistry/genetics, Models, Molecular, Mutagenesis, Site-Directed, Sequence Alignment
Metabolism	33674431	Novel 3-O-alpha-d-Galactosyl-alpha-l-Arabinofuranosidase for the Assimilation of Gum Arabic Arabinogalactan Protein in Bifidobacterium longum subsp. longum.	Sasaki Y, Horigome A, Odamaki T, Xiao JZ, Ishiwata A, Ito Y, Kitahara K, Fujita K	Appl Environ Microbiol	10.1128/AEM.02690-20	2021	Bacterial Proteins/genetics/metabolism, Bifidobacterium/enzymology/genetics, Galactans/metabolism, Glycoside Hydrolases/*genetics/metabolism, Gum Arabic	Enzymology
	34681443	Effect of Rosemary (Rosmarinus officinalis L.) Supplementation on Probiotic Yoghurt: Physicochemical Properties, Microbial Content, and Sensory Attributes.	Ali HI, Dey M, Alzubaidi AK, Alneamah SJA, Altemimi AB, Pratap-Singh A	Foods	10.3390/foods10102393	2021
Pathogenicity	35092420	Crystal structures of glycoside hydrolase family 136 lacto-N-biosidases from monkey gut- and human adult gut bacteria.	Yamada C, Katayama T, Fushinobu S	Biosci Biotechnol Biochem	10.1093/bbb/zbac015	2022	Animals, Bacterial Proteins/chemistry, Glycoside Hydrolases/chemistry, Haplorhini, Humans, Milk, Human, Oligosaccharides/chemistry
Metabolism	35235007	Two alpha-L-arabinofuranosidases from Bifidobacterium longum subsp. longum are involved in arabinoxylan utilization.	Komeno M, Yoshihara Y, Kawasaki J, Nabeshima W, Maeda K, Sasaki Y, Fujita K, Ashida H	Appl Microbiol Biotechnol	10.1007/s00253-022-11845-x	2022	Bifidobacterium/enzymology, Glycoside Hydrolases/genetics/metabolism, Substrate Specificity, Xylans/metabolism	Enzymology
	35783421	In vivo Trial of Bifidobacterium longum Revealed the Complex Network Correlations Between Gut Microbiota and Health Promotional Effects.	Kim YT, Kim CH, Kwon JG, Cho JH, Shin YS, Kim HB, Lee JH	Front Microbiol	10.3389/fmicb.2022.886934	2022

Reference

@id	authors	catalogue	doi/url	title	journal	pubmed
8612	Curators of the DSMZ	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 20219)	https://www.dsmz.de/collection/catalogue/details/culture/DSM-20219
20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.		10.1099/ijsem.0.004332	List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ
20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.		10.1016/j.syapm.2013.11.002	StrainInfo introduces electronic passports for microorganisms.	Syst Appl Microbiol. 37: 42-50 2014	24321274
38030	Curators of the CIP		https://brclims.pasteur.fr/brcWeb/souche/detail/1/10167
49449	Curators of the CCUG	Culture Collection University of Gothenburg (CCUG) (CCUG 28903)	https://www.ccug.se/strain?id=28903
66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann		https://diaspora-project.de/progress.html#genomes	Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)
67770	Curators of the JCM		https://jcm.brc.riken.jp/en/
68371				Automatically annotated from API 50CH acid
68382				Automatically annotated from API zym
69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.		https://microbeatlas.org/	MicrobeAtlas 1.0 beta
71356	Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.		10.60712/SI-ID376921.1	StrainInfo: A central database for resolving microbial strain identifiers
120652	Curators of the CIP	Collection of Institut Pasteur (CIP 64.62)	https://catalogue-crbip.pasteur.fr/fiche_catalogue.xhtml?crbip=CIP%2064.62