Strain identifier
BacDive ID: 169112
Type strain: 
Species: Burkholderia mallei
NCBI tax ID(s): 243160 (strain), 13373 (species)
version 9.3 (current version)
General
@ref: 20215
BacDive-ID: 169112
keywords: genome sequence, 16S sequence, Bacteria, Gram-negative
description: Burkholderia mallei NCTC 12938 is a Gram-negative bacterium of the family Burkholderiaceae.
NCBI tax id
| NCBI tax id | Matching level |
|---|---|
| 243160 | strain |
| 13373 | species |
doi: 10.13145/bacdive169112.20250331.9.3
Name and taxonomic classification
LPSN
- @ref: 20215
- description: domain/bacteria
- keyword: phylum/pseudomonadota
- domain: Bacteria
- phylum: Pseudomonadota
- class: Betaproteobacteria
- order: Burkholderiales
- family: Burkholderiaceae
- genus: Burkholderia
- species: Burkholderia mallei
- full scientific name: Burkholderia mallei (Zopf 1885) Yabuuchi et al. 1993
synonyms
@ref synonym 20215 Pseudomonas mallei 20215 Bacillus mallei 20215 Malleomyces mallei
@ref: 20215
domain: Bacteria
phylum: Pseudomonadota
class: Betaproteobacteria
order: Burkholderiales
family: Burkholderiaceae
genus: Burkholderia
species: Burkholderia mallei
full scientific name: Burkholderia mallei (Zopf 1885) Yabuuchi et al. 1993
type strain: yes
Morphology
cell morphology
| @ref | gram stain | confidence |
|---|---|---|
| 125439 | negative | 94.3 |
| 125438 | negative | 98.5 |
Physiology and metabolism
oxygen tolerance
- @ref: 125439
- oxygen tolerance: obligate aerobe
- confidence: 98.8
spore formation
- @ref: 125439
- spore formation: no
- confidence: 92.8
Isolation, sampling and environmental information
taxonmaps
- @ref: 69479
- File name: preview.99_22.png
- url: https://microbeatlas.org/index.html?action=taxon&taxon_id=90_12;96_18;97_18;98_21;99_22&stattab=map
- Last taxonomy: Burkholderia
- 16S sequence: AF110188
- Sequence Identity:
- Total samples: 15491
- soil counts: 4295
- aquatic counts: 1640
- animal counts: 7137
- plant counts: 2419
Safety information
risk assessment
- @ref: 20215
- biosafety level: 3
- biosafety level comment: Risk group
Sequence information
16S sequences
| @ref | description | accession | length | database | NCBI tax ID |
|---|---|---|---|---|---|
| 20215 | Burkholderia mallei strain ATCC 23344 16S ribosomal RNA gene, complete sequence | AF110188 | 1488 | nuccore | 13373 |
| 124043 | Burkholderia mallei gene for 16S rRNA, partial sequence, strain: ATCC 23344 (= EY 2233, = RH 627, = NCTC 7383). | D13057 | 160 | nuccore | 13373 |
Genome sequences
| @ref | description | accession | assembly level | database | NCBI tax ID |
|---|---|---|---|---|---|
| 66792 | Burkholderia mallei ATCC 23344 | GCA_000011705 | complete | ncbi | 243160 |
| 66792 | Burkholderia mallei NCTC12938 | GCA_900446245 | contig | ncbi | 13373 |
| 66792 | Burkholderia mallei ATCC 23344 | 243160.12 | complete | patric | 243160 |
| 66792 | Burkholderia mallei strain NCTC12938 | 13373.76 | wgs | patric | 13373 |
Genome-based predictions
predictions
| @ref | model | trait | description | prediction | confidence | training_data |
|---|---|---|---|---|---|---|
| 125438 | gram-positive | gram-positive | Positive reaction to Gram-staining | no | 98.5 | no |
| 125438 | anaerobic | anaerobic | Ability to grow under anoxygenic conditions (including facultative anaerobes) | no | 96.93 | no |
| 125438 | aerobic | aerobic | Ability to grow under oxygenic conditions (including facultative aerobes) | yes | 88.287 | no |
| 125438 | spore-forming | spore-forming | Ability to form endo- or exospores | no | 88.572 | no |
| 125438 | thermophile | thermophilic | Ability to grow at temperatures above or equal to 45°C | no | 98 | no |
| 125438 | motile2+ | flagellated | Ability to perform flagellated movement | yes | 83.568 | no |
| 125439 | BacteriaNet | spore_formation | Ability to form endo- or exospores | no | 92.8 | |
| 125439 | BacteriaNet | motility | Ability to perform movement | yes | 68.3 | |
| 125439 | BacteriaNet | gram_stain | Reaction to gram-staining | negative | 94.3 | |
| 125439 | BacteriaNet | oxygen_tolerance | Oxygenic conditions needed for growth | obligate aerobe | 98.8 |
External links
@ref: 20215
culture collection no.: NCTC 12938, ATCC 23344
straininfo link
- @ref: 115381
- straininfo: 87678
literature
| topic | Pubmed-ID | title | authors | journal | DOI | year | mesh | topic2 |
|---|---|---|---|---|---|---|---|---|
| Genetics | 11373120 | Identification of a Burkholderia mallei polysaccharide gene cluster by subtractive hybridization and demonstration that the encoded capsule is an essential virulence determinant. | DeShazer D, Waag DM, Fritz DL, Woods DE | Microb Pathog | 10.1006/mpat.2000.0430 | 2001 | Amino Acid Sequence, Animals, Bacterial Capsules/analysis/chemistry/*genetics, Base Composition, Base Sequence, Burkholderia/chemistry/genetics/*pathogenicity, Cloning, Molecular, Cricetinae, DNA Transposable Elements, Disease Models, Animal, Female, *Genes, Bacterial, Genome, Bacterial, Melioidosis/microbiology, Mice, Mice, Inbred BALB C, Microscopy, Immunoelectron, Molecular Sequence Data, Multigene Family, Mutation, Nucleic Acid Hybridization, Polysaccharides, Bacterial/analysis/*genetics, Sequence Alignment, Virulence | Enzymology |
| 11790757 | Molecular and physical characterization of Burkholderia mallei O antigens. | Burtnick MN, Brett PJ, Woods DE | J Bacteriol | 10.1128/JB.184.3.849-852.2002 | 2002 | Burkholderia/*immunology, Burkholderia pseudomallei/immunology, Cross Reactions, Genes, Bacterial, Multigene Family, O Antigens/chemistry/*genetics, Restriction Mapping, Serum Bactericidal Test | ||
| Genetics | 12081973 | Burkholderia thailandensis E125 harbors a temperate bacteriophage specific for Burkholderia mallei. | Woods DE, Jeddeloh JA, Fritz DL, DeShazer D | J Bacteriol | 10.1128/JB.184.14.4003-4017.2002 | 2002 | Burkholderia/*virology, DNA Methylation, Genome, Viral, O Antigens/physiology, RNA, Transfer, Pro/genetics, Siphoviridae/*genetics, Virus Integration | |
| Metabolism | 14614070 | Experimental aerogenic Burkholderia mallei (glanders) infection in the BALB/c mouse. | Lever MS, Nelson M, Ireland PI, Stagg AJ, Beedham RJ, Hall GA, Knight G, Titball RW | J Med Microbiol | 10.1099/jmm.0.05180-0 | 2003 | Aerosols, Animals, Antigens, Bacterial/analysis, Burkholderia Infections/metabolism/microbiology/*pathology, Burkholderia mallei, Colony Count, Microbial, Disease Models, Animal, Female, Immunohistochemistry, Lung/pathology, Mice, Mice, Inbred BALB C | |
| Metabolism | 14742564 | Type III secretion: a virulence factor delivery system essential for the pathogenicity of Burkholderia mallei. | Ulrich RL, DeShazer D | Infect Immun | 10.1128/IAI.72.2.1150-1154.2004 | 2004 | Animals, Burkholderia mallei/immunology/metabolism/*pathogenicity, Cricetinae, Female, Mesocricetus, Mice, Mice, Inbred BALB C, Vaccination, Virulence Factors/*metabolism | |
| Genetics | 15377793 | Structural flexibility in the Burkholderia mallei genome. | Nierman WC, DeShazer D, Kim HS, Tettelin H, Nelson KE, Feldblyum T, Ulrich RL, Ronning CM, Brinkac LM, Daugherty SC, Davidsen TD, Deboy RT, Dimitrov G, Dodson RJ, Durkin AS, Gwinn ML, Haft DH, Khouri H, Kolonay JF, Madupu R, Mohammoud Y, Nelson WC, Radune D, Romero CM, Sarria S, Selengut J, Shamblin C, Sullivan SA, White O, Yu Y, Zafar N, Zhou L, Fraser CM | Proc Natl Acad Sci U S A | 10.1073/pnas.0403306101 | 2004 | Animals, Base Composition/genetics, Base Sequence, Burkholderia mallei/*genetics/pathogenicity, Chromosomes, Bacterial/genetics, Cricetinae, *Genome, Bacterial, Glanders/microbiology, Liver/metabolism, Mesocricetus, Molecular Sequence Data, Multigene Family, Oligonucleotide Array Sequence Analysis, Open Reading Frames/genetics, Virulence | Metabolism |
| Phylogeny | 15501656 | Genome-wide comparison reveals great inter- and intraspecies variability in B. pseudomallei and B. mallei pathogens. | Monastyrskaya G, Fushan A, Abaev I, Filyukova O, Kostina M, Pecherskih E, Sverdlov E | Res Microbiol | 10.1016/j.resmic.2004.05.014 | 2004 | Bacterial Typing Techniques, Burkholderia/*classification/genetics, Burkholderia mallei/*classification/genetics, *Genetic Variation, *Genome, Bacterial, Humans, Molecular Sequence Data, Nucleic Acid Hybridization/methods, Sequence Analysis, DNA, Species Specificity | Genetics |
| Metabolism | 15501791 | Quorum sensing: a transcriptional regulatory system involved in the pathogenicity of Burkholderia mallei. | Ulrich RL, Deshazer D, Hines HB, Jeddeloh JA | Infect Immun | 10.1128/IAI.72.11.6589-6596.2004 | 2004 | 4-Butyrolactone/*analogs & derivatives/chemistry/metabolism, Animals, Bacterial Proteins/genetics/metabolism, Burkholderia mallei/*growth & development/*pathogenicity, Cricetinae, *Gene Expression Regulation, Bacterial, Gram-Negative Bacterial Infections/microbiology, Homoserine/*analogs & derivatives/metabolism, Humans, Lactones/metabolism, Mesocricetus, Mice, Mice, Inbred BALB C, Repressor Proteins/genetics/metabolism, *Signal Transduction, Trans-Activators/genetics/metabolism, Transcription Factors/genetics/metabolism, Transcription, Genetic, Virulence Factors/genetics/*metabolism | Pathogenicity |
| 15734072 | Aerogenic vaccination with a Burkholderia mallei auxotroph protects against aerosol-initiated glanders in mice. | Ulrich RL, Amemiya K, Waag DM, Roy CJ, DeShazer D | Vaccine | 10.1016/j.vaccine.2004.10.017 | 2005 | Aerosols, Animals, Antibodies, Bacterial/analysis/biosynthesis, Bacterial Vaccines/*administration & dosage/*immunology, Burkholderia mallei/*immunology, DNA, Bacterial/immunology, Female, Genetic Vectors, Glanders/*immunology/mortality/*prevention & control, Immunity, Cellular/immunology, Immunoglobulin G/biosynthesis, Mice, Mice, Inbred BALB C, Plasmids, Reverse Transcriptase Polymerase Chain Reaction, Survival Analysis, Th1 Cells/immunology, Th2 Cells/immunology, Vaccination/*methods, Vaccines, Attenuated/administration & dosage/immunology | ||
| Phylogeny | 15748995 | Genome-wide identification and mapping of variable sequences in the genomes of Burkholderia mallei and Burkholderia pseudomallei. | Fushan A, Monastyrskaya G, Abaev I, Kostina M, Filyukova O, Pecherskih E, Sverdlov E | Res Microbiol | 10.1016/j.resmic.2004.09.009 | 2004 | Animals, Bacterial Proteins/chemistry/genetics, Base Sequence, Burkholderia mallei/*classification/genetics, Burkholderia pseudomallei/*classification/genetics, Chromosome Mapping/*methods, Gene Library, *Genetic Markers, *Genetic Variation, *Genome, Bacterial, Humans, Molecular Sequence Data, Nucleic Acid Hybridization, Sequence Analysis, DNA | Genetics |
| Enzymology | 16466896 | Detection of the reemerging agent Burkholderia mallei in a recent outbreak of glanders in the United Arab Emirates by a newly developed fliP-based polymerase chain reaction assay. | Scholz HC, Joseph M, Tomaso H, Al Dahouk S, Witte A, Kinne J, Hagen RM, Wernery R, Wernery U, Neubauer H | Diagn Microbiol Infect Dis | 10.1016/j.diagmicrobio.2005.09.018 | 2006 | Animals, Burkholderia mallei/genetics/*isolation & purification, DNA, Bacterial/analysis, Disease Outbreaks/*veterinary, Flagellin/*genetics, Glanders/*epidemiology/microbiology, Horses, Polymerase Chain Reaction/*methods, United Arab Emirates/epidemiology | Phylogeny |
| Enzymology | 16546342 | Development of a polymerase chain reaction assay for the specific identification of Burkholderia mallei and differentiation from Burkholderia pseudomallei and other closely related Burkholderiaceae. | Ulrich RL, Ulrich MP, Schell MA, Kim HS, DeShazer D | Diagn Microbiol Infect Dis | 10.1016/j.diagmicrobio.2005.11.007 | 2006 | Bacterial Typing Techniques/*methods, Burkholderia mallei/*genetics/isolation & purification, Burkholderia pseudomallei/*genetics/isolation & purification, DNA Primers/chemistry, DNA, Bacterial/analysis/*genetics, *Genes, Bacterial, Genotype, Glanders/diagnosis/microbiology, Humans, Melioidosis/diagnosis/microbiology, Polymerase Chain Reaction/*methods, Sensitivity and Specificity | Phylogeny |
| Metabolism | 16790809 | The animal pathogen-like type III secretion system is required for the intracellular survival of Burkholderia mallei within J774.2 macrophages. | Ribot WJ, Ulrich RL | Infect Immun | 10.1128/IAI.01939-05 | 2006 | Animals, Burkholderia mallei/genetics/*pathogenicity/physiology, Cell Line, Intracellular Fluid/immunology/*metabolism/*microbiology, Lysosomal-Associated Membrane Protein 1/metabolism, Macrophages/metabolism/*microbiology/ultrastructure, Mice, Mutagenesis, Mutation | |
| Genetics | 16953889 | Genome sequence alterations detected upon passage of Burkholderia mallei ATCC 23344 in culture and in mammalian hosts. | Romero CM, DeShazer D, Feldblyum T, Ravel J, Woods D, Kim HS, Yu Y, Ronning CM, Nierman WC | BMC Genomics | 10.1186/1471-2164-7-228 | 2006 | Animals, Burkholderia mallei/*genetics/growth & development, Gene Deletion, Gene Expression Profiling, Genome, Bacterial/genetics, Glanders/*microbiology, Horses, Humans, Mice, Mice, Inbred BALB C, Minisatellite Repeats/genetics, Mutation/*genetics, Oligonucleotide Array Sequence Analysis, Polymorphism, Single Nucleotide/genetics, Sequence Analysis, DNA/methods | Pathogenicity |
| Genetics | 17391530 | ATP-binding cassette systems in Burkholderia pseudomallei and Burkholderia mallei. | Harland DN, Dassa E, Titball RW, Brown KA, Atkins HS | BMC Genomics | 10.1186/1471-2164-8-83 | 2007 | ATP-Binding Cassette Transporters/*genetics/physiology, Burkholderia mallei/*genetics/pathogenicity, Burkholderia pseudomallei/*genetics/pathogenicity, Chromosome Mapping, Drug Resistance, Bacterial/genetics, Genome, Bacterial, Iron/metabolism, Sequence Analysis, DNA, Virulence/genetics | Transcriptome |
| Enzymology | 17406228 | mini-Tn7 insertion in bacteria with multiple glmS-linked attTn7 sites: example Burkholderia mallei ATCC 23344. | Choi KH, DeShazer D, Schweizer HP | Nat Protoc | 10.1038/nprot.2006.25 | 2006 | *Attachment Sites, Microbiological, Bacterial Proteins/chemistry/genetics, Burkholderia mallei/*genetics, Chromosomes, Bacterial, Cloning, Molecular, *DNA Transposable Elements, Genetic Vectors, Transformation, Bacterial | |
| Metabolism | 17496085 | Octanoyl-homoserine lactone is the cognate signal for Burkholderia mallei BmaR1-BmaI1 quorum sensing. | Duerkop BA, Ulrich RL, Greenberg EP | J Bacteriol | 10.1128/JB.00317-07 | 2007 | 4-Butyrolactone/*analogs & derivatives/chemistry/isolation & purification/metabolism, Bacterial Proteins/genetics/*metabolism/physiology, Base Sequence, Binding Sites, Burkholderia mallei/genetics/*metabolism, Chromatography, High Pressure Liquid, Escherichia coli/genetics/metabolism, Mutation, Octanes/chemistry/metabolism, Promoter Regions, Genetic, Protein Binding, Quorum Sensing/genetics/*physiology, Sequence Homology, Nucleic Acid | Enzymology |
| Genetics | 17498635 | The factors shaping synonymous codon usage in the genome of Burkholderia mallei. | Zhao S, Zhang Q, Chen Z, Zhao Y, Zhong J | J Genet Genomics | 10.1016/S1673-8527(07)60039-3 | 2007 | Burkholderia mallei/*genetics, Codon/*genetics, *Gene Expression Regulation, Bacterial, Genome, Bacterial/*genetics, Genomics, Multivariate Analysis, Protein Biosynthesis | |
| Metabolism | 18614331 | A disruption of ctpA encoding carboxy-terminal protease attenuates Burkholderia mallei and induces partial protection in CD1 mice. | Bandara AB, DeShazer D, Inzana TJ, Sriranganathan N, Schurig GG, Boyle SM | Microb Pathog | 10.1016/j.micpath.2008.05.005 | 2008 | Animals, Antibodies, Bacterial/blood, Bacterial Proteins/*genetics/metabolism, Burkholderia mallei/*enzymology/genetics/immunology/*pathogenicity, Cell Line, Endopeptidases/*genetics/metabolism, Female, Glanders/immunology/*microbiology, Immunoglobulin G/blood, Macrophages/microbiology, Mice, Mice, Inbred Strains, *Sequence Deletion | Enzymology |
| Pathogenicity | 19426516 | Comparison of the in vitro and in vivo susceptibilities of Burkholderia mallei to Ceftazidime and Levofloxacin. | Judy BM, Whitlock GC, Torres AG, Estes DM | BMC Microbiol | 10.1186/1471-2180-9-88 | 2009 | Animals, Anti-Bacterial Agents/*pharmacology, Burkholderia mallei/*drug effects, Ceftazidime/*pharmacology, Cell Line, Drug Resistance, Bacterial, Female, Glanders/drug therapy/microbiology, *Levofloxacin, Macrophages/drug effects, Mice, Mice, Inbred BALB C, Microbial Sensitivity Tests, Ofloxacin/*pharmacology | |
| Phylogeny | 20920184 | Identification of Burkholderia mallei and Burkholderia pseudomallei adhesins for human respiratory epithelial cells. | Balder R, Lipski S, Lazarus JJ, Grose W, Wooten RM, Hogan RJ, Woods DE, Lafontaine ER | BMC Microbiol | 10.1186/1471-2180-10-250 | 2010 | Adhesins, Bacterial/*genetics, Amino Acid Sequence, Animals, Burkholderia mallei/classification/*genetics/pathogenicity, Burkholderia pseudomallei/classification/*genetics/pathogenicity, Cell Line, Epithelial Cells/*microbiology, Female, Gene Expression Regulation, Bacterial, Genes, Bacterial, Humans, Mice, Mice, Inbred BALB C, Molecular Sequence Data, Sequence Analysis, DNA, Species Specificity | Pathogenicity |
| Metabolism | 21115721 | Burkholderia thailandensis oacA mutants facilitate the expression of Burkholderia mallei-like O polysaccharides. | Brett PJ, Burtnick MN, Heiss C, Azadi P, DeShazer D, Woods DE, Gherardini FC | Infect Immun | 10.1128/IAI.01023-10 | 2010 | Bacterial Proteins/genetics/*metabolism, Burkholderia/*classification/*genetics, Carbohydrate Conformation, Gene Expression Regulation, Bacterial/*physiology, Mutation, O Antigens/genetics/*metabolism | Phylogeny |
| Pathogenicity | 21720554 | Alanine racemase mutants of Burkholderia pseudomallei and Burkholderia mallei and use of alanine racemase as a non-antibiotic-based selectable marker. | Zajdowicz SL, Jones-Carson J, Vazquez-Torres A, Jobling MG, Gill RE, Holmes RK | PLoS One | 10.1371/journal.pone.0021523 | 2011 | Alanine/pharmacology, Alanine Racemase/chemistry/*genetics, Amino Acid Sequence, Animals, Anti-Bacterial Agents/*pharmacology, Burkholderia mallei/drug effects/*enzymology/genetics/ultrastructure, Burkholderia pseudomallei/drug effects/*enzymology/genetics/ultrastructure, Gene Deletion, Genes, Bacterial/genetics, Genetic Loci/genetics, Genetic Markers, Macrophages, Peritoneal/drug effects/microbiology/ultrastructure, Mice, Microbial Viability/drug effects, Molecular Sequence Data, Mutation/*genetics, Periodic Acid/pharmacology, Plasmids/genetics, Polymerase Chain Reaction, Reproducibility of Results, Sequence Alignment | Enzymology |
| 21811486 | Autotransporters and Their Role in the Virulence of Burkholderia pseudomallei and Burkholderia mallei. | Lazar Adler NR, Stevens JM, Stevens MP, Galyov EE | Front Microbiol | 10.3389/fmicb.2011.00151 | 2011 | |||
| 22125550 | Protective antigens against glanders identified by expression library immunization. | Whitlock GC, Robida MD, Judy BM, Qazi O, Brown KA, Deeraksa A, Taylor K, Massey S, Loskutov A, Borovkov AY, Brown K, Cano JA, Torres AG, Estes DM, Sykes KF | Front Microbiol | 10.3389/fmicb.2011.00227 | 2011 | |||
| 23429539 | Virulence of Burkholderia mallei quorum-sensing mutants. | Majerczyk C, Kinman L, Han T, Bunt R, Greenberg EP | Infect Immun | 10.1128/IAI.00048-13 | 2013 | Animals, Bacterial Proteins/genetics/physiology, Burkholderia Infections/genetics/*microbiology, Burkholderia mallei/genetics/growth & development/*pathogenicity, Cells, Cultured, Disease Models, Animal, Female, Gene Expression Regulation, Bacterial, Macrophages/microbiology, Mice, Mice, Inbred BALB C, Quorum Sensing/*physiology, Virulence/genetics | ||
| Pathogenicity | 23800426 | Novel Burkholderia mallei virulence factors linked to specific host-pathogen protein interactions. | Memisevic V, Zavaljevski N, Pieper R, Rajagopala SV, Kwon K, Townsend K, Yu C, Yu X, DeShazer D, Reifman J, Wallqvist A | Mol Cell Proteomics | 10.1074/mcp.M113.029041 | 2013 | Animals, Bacterial Proteins/genetics/metabolism, Burkholderia mallei/genetics/*metabolism/*pathogenicity, Female, Host-Pathogen Interactions/genetics/*physiology, Humans, Mice, Mice, Inbred BALB C, Mutagenesis, Insertional, Protein Interaction Mapping, Proteomics, Two-Hybrid System Techniques, Virulence/genetics/physiology, Virulence Factors/genetics/*metabolism | Metabolism |
| Pathogenicity | 24098563 | Use of a safe, reproducible, and rapid aerosol delivery method to study infection by Burkholderia pseudomallei and Burkholderia mallei in mice. | Lafontaine ER, Zimmerman SM, Shaffer TL, Michel F, Gao X, Hogan RJ | PLoS One | 10.1371/journal.pone.0076804 | 2013 | Administration, Inhalation, Aerosols/*administration & dosage, Animals, Antibodies, Bacterial/*blood, Bacteremia/blood/*immunology/microbiology/pathology, Biological Warfare Agents, Burkholderia mallei/*immunology/pathogenicity, Burkholderia pseudomallei/*immunology/pathogenicity, Disease Models, Animal, Female, Glanders/blood/*immunology/microbiology/pathology, Horses, Humans, Lung/immunology/microbiology/pathology, Melioidosis/blood/*immunology/microbiology/pathology, Mice, Mice, Inbred BALB C, Spleen/immunology/microbiology/pathology | |
| 24379895 | Protective response to subunit vaccination against intranasal Burkholderia mallei and B. pseudomallei challenge. | Whitlock GC, Deeraksa A, Qazi O, Judy BM, Taylor K, Propst KL, Duffy AJ, Johnson K, Kitto GB, Brown KA, Dow SW, Torres AG, Estes DM | Procedia Vaccinol | 10.1016/j.provac.2010.03.013 | 2010 | |||
| Metabolism | 24731253 | Characterization of an autotransporter adhesin protein shared by Burkholderia mallei and Burkholderia pseudomallei. | Lafontaine ER, Balder R, Michel F, Hogan RJ | BMC Microbiol | 10.1186/1471-2180-14-92 | 2014 | Adhesins, Bacterial/genetics/*metabolism, Animals, *Bacterial Adhesion, Bacterial Outer Membrane Proteins/genetics/metabolism, Burkholderia mallei/genetics/*physiology, Burkholderia pseudomallei/genetics/*physiology, Epithelial Cells/microbiology, Escherichia coli/genetics/physiology, Female, Gene Deletion, Gene Expression, Humans, Membrane Transport Proteins/genetics/*metabolism, Mice, Mice, Inbred BALB C, Recombinant Proteins/genetics/metabolism | Pathogenicity |
| Metabolism | 25030112 | DBSecSys: a database of Burkholderia mallei secretion systems. | Memisevic V, Kumar K, Cheng L, Zavaljevski N, DeShazer D, Wallqvist A, Reifman J | BMC Bioinformatics | 10.1186/1471-2105-15-244 | 2014 | Animals, Bacterial Proteins/*metabolism, *Bacterial Secretion Systems, Burkholderia mallei/metabolism/pathogenicity/*physiology, *Databases, Protein, Host-Pathogen Interactions, Humans, Mice, Virulence Factors/metabolism | Pathogenicity |
| Pathogenicity | 25503969 | Oropharyngeal aspiration of Burkholderia mallei and Burkholderia pseudomallei in BALB/c mice. | Schully KL, Bell MG, Ward JM, Keane-Myers AM | PLoS One | 10.1371/journal.pone.0115066 | 2014 | Acute Disease, Animals, Bacterial Infections/immunology/*pathology/transmission, Burkholderia mallei/immunology/*pathogenicity, Burkholderia pseudomallei/immunology/*pathogenicity, Disease Models, Animal, Female, Host-Pathogen Interactions/immunology, Humans, *Immunity, Innate, Mice, Mice, Inbred BALB C, Post-Exposure Prophylaxis | |
| Pathogenicity | 25738731 | Mining host-pathogen protein interactions to characterize Burkholderia mallei infectivity mechanisms. | Memisevic V, Zavaljevski N, Rajagopala SV, Kwon K, Pieper R, DeShazer D, Reifman J, Wallqvist A | PLoS Comput Biol | 10.1371/journal.pcbi.1004088 | 2015 | Algorithms, Animals, Bacterial Proteins/physiology, Burkholderia mallei/*pathogenicity/*physiology, Cluster Analysis, Computational Biology, Focal Adhesions, Glanders/microbiology/physiopathology, Host-Pathogen Interactions/*physiology, Humans, Mice, Protein Interaction Maps/physiology, Signal Transduction/physiology, Virulence Factors/metabolism | Metabolism |
| Pathogenicity | 25860021 | Use of the common marmoset to study Burkholderia mallei infection. | Jelesijevic T, Zimmerman SM, Harvey SB, Mead DG, Shaffer TL, Estes DM, Michel F, Quinn FD, Hogan RJ, Lafontaine ER | PLoS One | 10.1371/journal.pone.0124181 | 2015 | Administration, Intranasal, Animals, Bacterial Load, Burkholderia mallei/*pathogenicity, Callithrix/*microbiology, Disease Models, Animal, Female, Glanders/*etiology/pathology/transmission, Horses, Humans, Liver/microbiology/pathology, Lung/microbiology/pathology, Male, Species Specificity, Spleen/microbiology/pathology, Zoonoses/etiology/pathology/transmission | Phylogeny |
| Metabolism | 25993100 | The Autotransporter BpaB Contributes to the Virulence of Burkholderia mallei in an Aerosol Model of Infection. | Zimmerman SM, Michel F, Hogan RJ, Lafontaine ER | PLoS One | 10.1371/journal.pone.0126437 | 2015 | Aerosols, Animals, Antibodies, Bacterial/chemistry, Antibodies, Monoclonal/chemistry, Bacterial Proteins/chemistry/*genetics/metabolism, Biofilms/*growth & development, Burkholderia mallei/*genetics/metabolism/*pathogenicity, Cell Line, Cloning, Molecular, Epithelial Cells/microbiology/pathology, Escherichia coli/genetics/metabolism, Female, Gene Deletion, Gene Expression, Glanders/*microbiology/mortality/pathology/transmission, Humans, Macrophages/microbiology/pathology, Mice, Mice, Inbred BALB C, Recombinant Proteins/genetics/metabolism, Survival Analysis, Type V Secretion Systems/chemistry/*genetics/metabolism, Virulence | Enzymology |
| Metabolism | 26955620 | Phenotypic Characterization of a Novel Virulence-Factor Deletion Strain of Burkholderia mallei That Provides Partial Protection against Inhalational Glanders in Mice. | Bozue JA, Chaudhury S, Amemiya K, Chua J, Cote CK, Toothman RG, Dankmeyer JL, Klimko CP, Wilhelmsen CL, Raymond JW, Zavaljevski N, Reifman J, Wallqvist A | Front Cell Infect Microbiol | 10.3389/fcimb.2016.00021 | 2016 | Administration, Inhalation, Aerosols, Animals, Antibodies, Bacterial/*immunology, Bacterial Vaccines/*immunology, Burkholderia mallei/genetics/*immunology/*pathogenicity, Cytokines/metabolism, Female, Gene Deletion, Glanders/*immunology/microbiology, Host-Pathogen Interactions, Immunoglobulin G/*immunology, Macrophages/immunology, Mice, Mice, Inbred BALB C, Vaccination, Vaccines, Attenuated/immunology, Virulence/genetics | Pathogenicity |
| Metabolism | 27650316 | DBSecSys 2.0: a database of Burkholderia mallei and Burkholderia pseudomallei secretion systems. | Memisevic V, Kumar K, Zavaljevski N, DeShazer D, Wallqvist A, Reifman J | BMC Bioinformatics | 10.1186/s12859-016-1242-z | 2016 | Animals, Bacterial Proteins/genetics/*metabolism, Bacterial Secretion Systems/genetics/*metabolism, Burkholderia mallei/genetics/metabolism/*pathogenicity, Burkholderia pseudomallei/genetics/metabolism/*pathogenicity, *Databases, Protein, Humans, Mice, Virulence Factors/genetics/metabolism | Pathogenicity |
| 28507073 | Antibodies against In Vivo-Expressed Antigens Are Sufficient To Protect against Lethal Aerosol Infection with Burkholderia mallei and Burkholderia pseudomallei. | Zimmerman SM, Dyke JS, Jelesijevic TP, Michel F, Lafontaine ER, Hogan RJ | Infect Immun | 10.1128/IAI.00102-17 | 2017 | Animals, Antibodies, Bacterial/*immunology, Bacterial Proteins/genetics, Burkholderia mallei/genetics/growth & development/*immunology/pathogenicity, Burkholderia pseudomallei/*immunology/pathogenicity, Disease Models, Animal, Glanders/immunology/microbiology/prevention & control, Immunoglobulin G/immunology, Melioidosis/immunology/microbiology/*prevention & control, Mice, Mice, Inbred BALB C, Mutation, Vaccination, Virulence Factors/genetics | ||
| Pathogenicity | 31306423 | Evaluation of Burkholderia mallei DeltatonB Deltahcp1 (CLH001) as a live attenuated vaccine in murine models of glanders and melioidosis. | Khakhum N, Bharaj P, Myers JN, Tapia D, Walker DH, Endsley JJ, Torres AG | PLoS Negl Trop Dis | 10.1371/journal.pntd.0007578 | 2019 | Animals, Antibodies, Bacterial/immunology, Bacterial Proteins/genetics/*immunology, Bacterial Vaccines/*immunology, Burkholderia mallei/genetics/*immunology, CD8-Positive T-Lymphocytes/immunology, Disease Models, Animal, Female, Glanders/*immunology/microbiology/prevention & control, Humans, Immunity, Humoral, *Immunization, Melioidosis/*immunology/microbiology/prevention & control, Membrane Proteins/genetics/*immunology, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Vaccination, Vaccines, Attenuated/*immunology, Virulence Factors/genetics/immunology | |
| 32799724 | The Peptidoglycan-associated lipoprotein Pal contributes to the virulence of Burkholderia mallei and provides protection against lethal aerosol challenge. | Dyke JS, Huertas-Diaz MC, Michel F, Holladay NE, Hogan RJ, He B, Lafontaine ER | Virulence | 10.1080/21505594.2020.1804275 | 2020 | Aerosols, Animals, Bacterial Vaccines/administration & dosage/*immunology, Burkholderia mallei/*chemistry/immunology/*pathogenicity, Cell Line, Female, Genetic Vectors, Immunization, Lipoproteins/administration & dosage/*immunology, Macrophages/microbiology, Melioidosis/immunology/*prevention & control, Mice, Mice, Inbred BALB C, Parainfluenza Virus 5/genetics, Peptidoglycan/*chemistry, Vaccines, Synthetic/administration & dosage/immunology, Virulence | ||
| Pathogenicity | 35467945 | Validation of a Lateral Flow Test for the Presumptive Identification of the Presence of Burkholderia mallei or Burkholderia pseudomallei in Environmental Samples. | Venkateswaran KS, Parameswaran N, Sarwar J, Plummer A, Santos A, Pillai CA, Bowen S, Granville M, Selvan S, Babu P, Thirunavukkarasu N, Venkateswaran N, Sharma S, Morse SA, Anderson K, Hodge DR, Pillai SP | Health Secur | 10.1089/hs.2021.0168 | 2022 | *Burkholderia mallei, *Burkholderia pseudomallei, Humans, *Melioidosis/diagnosis, Phylogeny, Plant Extracts | Phylogeny |
Reference
| @id | authors | title | doi/url |
|---|---|---|---|
| 20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M. | List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ | 10.1099/ijsem.0.004332 |
| 66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | https://diaspora-project.de/progress.html#genomes |
| 69479 | João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich. | MicrobeAtlas 1.0 beta | https://microbeatlas.org/ |
| 115381 | Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J. | StrainInfo: A central database for resolving microbial strain identifiers | 10.60712/SI-ID87678.1 |
| 124043 | Isabel Schober, Julia Koblitz | Data extracted from sequence databases, automatically matched based on designation and taxonomy | |
| 125438 | Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann | Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets | 10.1101/2024.08.12.607695 |
| 125439 | Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy | deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 | https://github.com/GenomeNet/deepG |