Strain identifier
BacDive ID: 165408
Type strain: 
Species: Cutibacterium acnes subsp. acnes
Strain history: Y. Benno <-- T. Mitsuoka <-- ATCC 11827 <-- H. P. Seeliger strain Gerath <-- Lentze.
NCBI tax ID(s): 1734925 (subspecies)
version 9.3 (current version)
General
@ref: 67770
BacDive-ID: 165408
keywords: genome sequence, 16S sequence, Bacteria, mesophilic, polysaccharide production
description: Cutibacterium acnes subsp. acnes JCM 6495 is a mesophilic bacterium that produces polysaccharides.
NCBI tax id
- NCBI tax id: 1734925
- Matching level: subspecies
strain history
- @ref: 67770
- history: Y. Benno <-- T. Mitsuoka <-- ATCC 11827 <-- H. P. Seeliger strain Gerath <-- Lentze.
doi: 10.13145/bacdive165408.20250331.9.3
Name and taxonomic classification
LPSN
- @ref: 20215
- description: domain/bacteria
- keyword: phylum/actinomycetota
- domain: Bacteria
- phylum: Actinomycetota
- class: Actinomycetes
- order: Propionibacteriales
- family: Propionibacteriaceae
- genus: Cutibacterium
- species: Cutibacterium acnes subsp. acnes
- full scientific name: Cutibacterium acnes subsp. acnes (Gilchrist 1900) Nouioui et al. 2018
synonyms
- @ref: 20215
- synonym: Propionibacterium acnes subsp. acnes
@ref: 67770
domain: Bacteria
phylum: Actinobacteria
class: Actinobacteria
order: Propionibacteriales
family: Propionibacteriaceae
genus: Cutibacterium
species: Cutibacterium acnes subsp. acnes
full scientific name: Cutibacterium acnes subsp. acnes (Gilchrist 1900) Nouioui et al. 2018
type strain: no
Morphology
cell morphology
| @ref | motility | confidence | gram stain |
|---|---|---|---|
| 125438 | no | 94 | |
| 125438 | 90.058 | positive | |
| 125439 | 93.1 | positive | |
| 125439 | no | 90.9 |
Culture and growth conditions
culture temp
- @ref: 67770
- growth: positive
- type: growth
- temperature: 37
Physiology and metabolism
oxygen tolerance
- @ref: 125439
- oxygen tolerance: anaerobe
- confidence: 92.4
compound production
- @ref: 67770
- compound: Lipopolysaccharide (US Pat. 4,746,511)
Isolation, sampling and environmental information
taxonmaps
- @ref: 69479
- File name: preview.99_663.png
- url: https://microbeatlas.org/index.html?action=taxon&taxon_id=90_15360;96_410;97_465;98_535;99_663&stattab=map
- Last taxonomy: Cutibacterium acnes
- 16S sequence: AB693168
- Sequence Identity:
- Total samples: 60269
- soil counts: 3573
- aquatic counts: 7473
- animal counts: 47966
- plant counts: 1257
Sequence information
16S sequences
- @ref: 67770
- description: Propionibacterium acnes gene for 16S ribosomal RNA, partial sequence, strain: JCM 6495
- accession: AB693168
- length: 1486
- database: nuccore
- NCBI tax ID: 1747
Genome sequences
| @ref | description | accession | assembly level | database | NCBI tax ID |
|---|---|---|---|---|---|
| 66792 | Cutibacterium acnes strain ATCC 11827 | 1747.867 | wgs | patric | 1747 |
| 67770 | Cutibacterium acnes ATCC 11827 | GCA_008868325 | contig | ncbi | 1747 |
GC content
- @ref: 67770
- GC-content: 57
- method: thermal denaturation, midpoint method (Tm)
Genome-based predictions
predictions
| @ref | model | trait | description | prediction | confidence | training_data |
|---|---|---|---|---|---|---|
| 125438 | gram-positive | gram-positive | Positive reaction to Gram-staining | yes | 90.058 | no |
| 125438 | anaerobic | anaerobic | Ability to grow under anoxygenic conditions (including facultative anaerobes) | no | 64.73 | no |
| 125438 | spore-forming | spore-forming | Ability to form endo- or exospores | no | 79.931 | no |
| 125438 | aerobic | aerobic | Ability to grow under oxygenic conditions (including facultative aerobes) | no | 69.685 | no |
| 125438 | thermophile | thermophilic | Ability to grow at temperatures above or equal to 45°C | no | 93.077 | yes |
| 125438 | motile2+ | flagellated | Ability to perform flagellated movement | no | 94 | no |
| 125439 | BacteriaNet | spore_formation | Ability to form endo- or exospores | no | 88.4 | |
| 125439 | BacteriaNet | motility | Ability to perform movement | no | 90.9 | |
| 125439 | BacteriaNet | gram_stain | Reaction to gram-staining | positive | 93.1 | |
| 125439 | BacteriaNet | oxygen_tolerance | Oxygenic conditions needed for growth | anaerobe | 92.4 |
External links
@ref: 67770
culture collection no.: JCM 6495, ATCC 11827, KCTC 5012, VPI 4979
literature
| topic | Pubmed-ID | title | authors | journal | DOI | year | mesh | topic2 |
|---|---|---|---|---|---|---|---|---|
| Enzymology | 2818796 | Two-dimensional gel electrophoresis of ribosomal proteins from Propionibacterium acnes and granulosum. | Dekio S, Hashimoto K, Makino M | Zentralbl Bakteriol | 10.1016/s0934-8840(89)80103-3 | 1989 | Animals, Electrophoresis, Gel, Two-Dimensional, Humans, Propionibacterium/*analysis/genetics, Propionibacterium acnes/*analysis/genetics, Ribosomal Proteins/*analysis | Pathogenicity |
| Pathogenicity | 16511806 | Long-chain 3-acyl-4-hydroxycoumarins: structure and antibacterial activity. | Cravotto G, Tagliapietra S, Cappello R, Palmisano G, Curini M, Boccalini M | Arch Pharm (Weinheim) | 10.1002/ardp.200500127 | 2006 | 4-Hydroxycoumarins/*chemical synthesis/pharmacology, Anti-Bacterial Agents/*chemical synthesis/pharmacology, Microbial Sensitivity Tests, Staphylococcus aureus/drug effects, Staphylococcus epidermidis/drug effects, Structure-Activity Relationship | |
| Genetics | 23115111 | In vitro emergence of rifampicin resistance in Propionibacterium acnes and molecular characterization of mutations in the rpoB gene. | Furustrand Tafin U, Trampuz A, Corvec S | J Antimicrob Chemother | 10.1093/jac/dks428 | 2012 | Anti-Bacterial Agents/*pharmacology, DNA Mutational Analysis, DNA-Directed RNA Polymerases/*genetics, *Drug Resistance, Bacterial, Microbial Sensitivity Tests, Molecular Sequence Data, *Mutation, Missense, Propionibacterium acnes/*drug effects/genetics, Rifampin/*pharmacology, Sequence Analysis, DNA, Serial Passage | Transcriptome |
| Pathogenicity | 24289140 | Evaluation of antibacterial and anti-inflammatory activities of less polar ginsenosides produced from polar ginsenosides by heat-transformation. | Wang L, Yang X, Yu X, Yao Y, Ren G | J Agric Food Chem | 10.1021/jf404461q | 2013 | Animals, Anti-Bacterial Agents/*chemistry/*pharmacology, Anti-Inflammatory Agents/*chemistry/*pharmacology, Cell Line, Ginsenosides/*chemistry/*pharmacology, Hot Temperature, Macrophages/drug effects/immunology, Mice, Microbial Sensitivity Tests, Molecular Structure, Propionibacterium acnes/drug effects | Stress |
| Pathogenicity | 26806150 | In vitro antimicrobial activity of benzoyl peroxide against Propionibacterium acnes assessed by a novel susceptibility testing method. | Okamoto K, Ikeda F, Kanayama S, Nakajima A, Matsumoto T, Ishii R, Umehara M, Gotoh N, Hayashi N, Iyoda T, Matsuzaki K, Matsumoto S, Kawashima M | J Infect Chemother | 10.1016/j.jiac.2015.12.010 | 2016 | Acne Vulgaris/microbiology, Anti-Bacterial Agents/*pharmacology, Benzoyl Peroxide/*pharmacology, Culture Media, Humans, Microbial Sensitivity Tests/*methods, Propionibacterium acnes/*drug effects/isolation & purification, Reproducibility of Results | Cultivation |
| Genetics | 28602804 | In vitro emergence of fluoroquinolone resistance in Cutibacterium (formerly Propionibacterium) acnes and molecular characterization of mutations in the gyrA gene. | Takoudju EM, Guillouzouic A, Kambarev S, Pecorari F, Corvec S | Anaerobe | 10.1016/j.anaerobe.2017.06.005 | 2017 | Anti-Bacterial Agents/*pharmacology, Bacteriological Techniques, DNA Gyrase/*genetics, *Drug Resistance, Bacterial, Fluoroquinolones/*pharmacology, Genotype, Microbial Sensitivity Tests, Mutation Rate, *Mutation, Missense, Propionibacterium acnes/*drug effects/*genetics, Selection, Genetic, Sequence Analysis, DNA | Transcriptome |
| 29574906 | The in vitro antimicrobial evaluation of commercially essential oils and their combinations against acne. | Orchard A, van Vuuren SF, Viljoen AM, Kamatou G | Int J Cosmet Sci | 10.1111/ics.12456 | 2018 | |||
| 32429267 | Radial Extracorporeal Shock Wave Therapy Against Cutibacterium acnes Implant-Associated Infections: An in Vitro Trial. | Tsikopoulos K, Drago L, Koutras G, Givissis P, Vagdatli E, Soukiouroglou P, Papaioannidou P | Microorganisms | 10.3390/microorganisms8050743 | 2020 | |||
| Pathogenicity | 32712375 | Lactobacillus paraplantarum THG-G10 as a potential anti-acne agent with anti-bacterial and anti-inflammatory activities. | Cha H, Kim SK, Kook M, Yi TH | Anaerobe | 10.1016/j.anaerobe.2020.102243 | 2020 | Acne Vulgaris/*drug therapy/microbiology, Animals, Anti-Bacterial Agents/*pharmacology, Anti-Inflammatory Agents/*pharmacology, Cell Line, Cell Survival, DNA, Bacterial/genetics, HaCaT Cells, Humans, *Lactobacillus, Mice, Microbial Sensitivity Tests, Phylogeny, Propionibacterium acnes/*drug effects, RAW 264.7 Cells, RNA, Ribosomal, 16S/genetics, Republic of Korea | Phylogeny |
| 33425708 | Peel-off emulgel mask of Cocos nucifera L. Extract using gelling agent carbomer 940 as antiacne against Propionibacterium acnes ATCC 11827. | Hariyadi DM, Isnaeni I, Sudarma S, Suciati S, Rosita N | J Adv Pharm Technol Res | 10.4103/japtr.JAPTR_51_20 | 2020 |
Reference
| @id | authors | title | doi/url |
|---|---|---|---|
| 20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M. | List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ | 10.1099/ijsem.0.004332 |
| 66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | https://diaspora-project.de/progress.html#genomes |
| 67770 | Curators of the JCM | https://jcm.brc.riken.jp/en/ | |
| 69479 | João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich. | MicrobeAtlas 1.0 beta | https://microbeatlas.org/ |
| 125438 | Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann | Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets | 10.1101/2024.08.12.607695 |
| 125439 | Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy | deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 | https://github.com/GenomeNet/deepG |