Strain identifier

BacDive ID: 160395

Type strain: No

Species: Staphylococcus aureus

Strain Designation: CC22-MRSA-IV, Barnim"(IsolateA257)

Strain history: <- L. Corsini; PhagoMed Biopharma GmbH; CC22-MRSA-IV

NCBI tax ID(s): 1280 (species)

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General

@ref: 67301

BacDive-ID: 160395

DSM-Number: 111210

keywords: Bacteria, mesophilic, human pathogen

description: Staphylococcus aureus CC22-MRSA-IV is a mesophilic human pathogen that was isolated from abscess or skin/soft tissue infection .

NCBI tax id

  • NCBI tax id: 1280
  • Matching level: species

strain history

  • @ref: 67301
  • history: <- L. Corsini; PhagoMed Biopharma GmbH; CC22-MRSA-IV

doi: 10.13145/bacdive160395.20230509.8.1

Name and taxonomic classification

LPSN

  • @ref: 20215
  • description: domain/bacteria
  • keyword: phylum/bacillota
  • domain: Bacteria
  • phylum: Bacillota
  • class: Bacilli
  • order: Caryophanales
  • family: Staphylococcaceae
  • genus: Staphylococcus
  • species: Staphylococcus aureus
  • full scientific name: Staphylococcus aureus Rosenbach 1884 (Approved Lists 1980)

  • synonyms

    • @ref: 20215
    • synonym: Staphylococcus aureus subsp. anaerobius

@ref: 67301

domain: Bacteria

phylum: Firmicutes

class: Bacilli

order: Caryophanales

family: Staphylococcaceae

genus: Staphylococcus

species: Staphylococcus aureus

full scientific name: Staphylococcus aureus Rosenbach 1884

strain designation: CC22-MRSA-IV, Barnim"(IsolateA257)

type strain: no

Culture and growth conditions

culture medium

@refnamegrowthlinkcomposition
67301TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92)yeshttps://mediadive.dsmz.de/medium/92Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water
67301COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)yeshttps://mediadive.dsmz.de/medium/693Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base

culture temp

  • @ref: 67301
  • growth: positive
  • type: growth
  • temperature: 37
  • range: mesophilic

Physiology and metabolism

metabolite utilization

@refChebi-IDmetaboliteutilization activitykind of utilization tested
6837516199urea-hydrolysis
6837529016arginine+hydrolysis
6837518257ornithine-degradation
683754853esculin-hydrolysis
6837517634D-glucose+fermentation
6837515824D-fructose+fermentation
6837516024D-mannose+fermentation
6837517306maltose+fermentation
6837517716lactose+fermentation
6837527082trehalose+fermentation
6837516899D-mannitol+fermentation
6837516634raffinose-fermentation
6837516988D-ribose-fermentation
6837517057cellobiose-fermentation
6837517632nitrate+reduction
6837517992sucrose+fermentation
6837559640N-acetylglucosamine+fermentation
6837532528turanose+fermentation
6837522599arabinose-fermentation

antibiotic resistance

  • @ref: 68375
  • ChEBI: 28368
  • metabolite: novobiocin
  • is antibiotic: yes
  • is resistant: yes
  • resistance conc.: 1.8 µg

metabolite production

  • @ref: 68375
  • Chebi-ID: 15688
  • metabolite: acetoin
  • production: yes

metabolite tests

  • @ref: 68375
  • Chebi-ID: 15688
  • metabolite: acetoin
  • voges-proskauer-test: +

enzymes

@refvalueactivityec
68375beta-glucuronidase-3.2.1.31
68375pyrrolidonyl arylamidase+3.4.19.3
68375alkaline phosphatase+3.1.3.1
68375L-arginine arylamidase-
68375beta-galactosidase-3.2.1.23
68375beta-glucosidase-3.2.1.21
68375ornithine decarboxylase-4.1.1.17
68375arginine dihydrolase+3.5.3.6
68375urease-3.5.1.5

API ID32STA

@refUREADH ArgODCESCGLUFRUMNEMALLACTREMANRAFRIBCELNITVPbeta GALArgAPALPyrANOVOSACNAGTURARAbeta GUR
67301-+--+++++++---++--++++++--

Isolation, sampling and environmental information

isolation

  • @ref: 67301
  • sample type: abscess or skin/soft tissue infection (human)
  • geographic location: Dresden
  • country: Germany
  • origin.country: DEU
  • continent: Europe
  • latitude: 51.0557
  • longitude: 13.7806

Safety information

risk assessment

  • @ref: 67301
  • pathogenicity human: yes
  • pathogenicity animal: yes
  • biosafety level: 2
  • biosafety level comment: Risk group (German classification)

External links

@ref: 67301

culture collection no.: DSM 111210

straininfo link

  • @ref: 112644
  • straininfo: 405235

literature

topicPubmed-IDtitleauthorsjournalDOIyearmeshtopic2
Pathogenicity22140542Clonal replacement of epidemic methicillin-resistant Staphylococcus aureus strains in a German university hospital over a period of eleven years.Albrecht N, Jatzwauk L, Slickers P, Ehricht R, Monecke SPLoS One10.1371/journal.pone.00281892011Adolescent, Adult, Child, Clone Cells, Epidemics/*statistics & numerical data, Female, Germany/epidemiology, Hospitals, University/*statistics & numerical data, Humans, Male, Methicillin-Resistant Staphylococcus aureus/*isolation & purification, Middle Aged, Staphylococcal Infections/*epidemiology/*microbiology, Time FactorsEnzymology
Enzymology22972817Characterization of methicillin-resistant Staphylococcus aureus strains recovered from a phase IV clinical trial for linezolid versus vancomycin for treatment of nosocomial pneumonia.Mendes RE, Deshpande LM, Smyth DS, Shopsin B, Farrell DJ, Jones RNJ Clin Microbiol10.1128/JCM.02024-122012Acetamides/*therapeutic use, Anti-Bacterial Agents/*therapeutic use, Cluster Analysis, Cross Infection/*drug therapy/microbiology, DNA, Bacterial/genetics, Double-Blind Method, Electrophoresis, Gel, Pulsed-Field, Genotype, Humans, Linezolid, Methicillin-Resistant Staphylococcus aureus/*isolation & purification, Microbial Sensitivity Tests, Molecular Epidemiology, Multilocus Sequence Typing, Oxazolidinones/*therapeutic use, Pneumonia, Staphylococcal/*drug therapy/microbiology, Prospective Studies, Staphylococcal Protein A/genetics, United States, Vancomycin/*therapeutic useGenetics
Pathogenicity27578204Diversity of methicillin-resistant Staphylococcus aureus CC22-MRSA-IV from Saudi Arabia and the Gulf region.Senok A, Somily A, Raji A, Gawlik D, Al-Shahrani F, Baqi S, Boswihi S, Skakni L, Udo EE, Weber S, Ehricht R, Monecke SInt J Infect Dis10.1016/j.ijid.2016.08.0162016Germany, Humans, India, Kuwait, Male, Methicillin-Resistant Staphylococcus aureus/*isolation & purification, Middle Aged, Saudi Arabia/epidemiology, Staphylococcal Infections/epidemiology/*microbiology, United Arab Emirates, Virulence FactorsEnzymology
29184755Dissemination of high-level mupirocin-resistant CC22-MRSA-IV in Saxony.Monecke S, Ruppelt-Lorz A, Muller E, Reissig A, Thurmer A, Shore AC, Coleman DC, Ehricht R, Jatzwauk LGMS Hyg Infect Control10.3205/dgkh0003042017
Pathogenicity30473348Methicillin-resistant Staphylococcus aureus CC22-MRSA-IV as an agent of dairy cow intramammary infections.Magro G, Rebolini M, Beretta D, Piccinini RVet Microbiol10.1016/j.vetmic.2018.10.0212018Animals, Anti-Bacterial Agents/pharmacology, Cattle, Female, Genotype, Humans, Lactation, Mammary Glands, Animal/*microbiology, Mastitis, Bovine/epidemiology/*microbiology/prevention & control/transmission, Methicillin/pharmacology, Methicillin-Resistant Staphylococcus aureus/drug effects/*genetics/isolation & purification, Microbial Sensitivity Tests, Milk/microbiology, Oligonucleotide Array Sequence Analysis, Staphylococcal Infections/epidemiology/microbiology/prevention & control/*veterinary, Zoonoses/*epidemiology/microbiology/prevention & control/transmissionGenetics
Genetics31482419Genotyping of methicillin-resistant Staphylococcus aureus from sepsis patients in Pakistan and detection of antibodies against staphylococcal virulence factors.Monecke S, Syed MA, Khan MA, Ahmed S, Tabassum S, Gawlik D, Muller E, Reissig A, Braun SD, Ehricht REur J Clin Microbiol Infect Dis10.1007/s10096-019-03695-92019Adult, Afghanistan, Antibodies, Bacterial/*blood, Bacterial Typing Techniques, Female, Genotype, Humans, Male, Methicillin-Resistant Staphylococcus aureus/*classification/pathogenicity, Pakistan, Protein Array Analysis, Sepsis/*microbiology, Staphylococcal Infections/*blood/microbiology, Virulence Factors/genetics/*immunologyPathogenicity
Enzymology31811246Molecular Characterization of Methicillin- Resistant Staphylococcus aureus in a Tertiary Care hospital in Kuwait.Alfouzan W, Udo EE, Modhaffer A, Alosaimi ASci Rep10.1038/s41598-019-54794-82019Community-Acquired Infections/drug therapy/epidemiology/*microbiology, Cross Infection/drug therapy/epidemiology/*microbiology, DNA, Bacterial/genetics/isolation & purification, Drug Resistance, Multiple, Bacterial/genetics, Female, Humans, Kuwait/epidemiology, Male, Methicillin/*pharmacology/therapeutic use, Methicillin Resistance/genetics, Methicillin-Resistant Staphylococcus aureus/drug effects/*genetics/isolation & purification/pathogenicity, Microbial Sensitivity Tests, Molecular Epidemiology, Molecular Typing, Oligonucleotide Array Sequence Analysis, Staphylococcal Infections/drug therapy/epidemiology/*microbiology, Tertiary Care Centers/statistics & numerical data, Virulence Factors/genetics/isolation & purificationPhylogeny
31865293Genotyping of Staphylococcus aureus associated with nasal colonization among healthcare workers using DNA microarray.Senok AC, Somily A, Raji M, Garaween G, Kabil M, Shibl A, Monecke S, Ehricht RJ Infect Dev Ctries10.3855/jidc.103282018
Genetics31910349Molecular Characterization of Staphylococcus aureus Isolates Associated with Nasal Colonization and Environmental Contamination in Academic Dental Clinics.Senok A, Nassar R, Kaklamanos EG, Belhoul K, Abu Fanas S, Nassar M, Azar AJ, Muller E, Reissig A, Gawlik D, Monecke S, Ehricht RMicrob Drug Resist10.1089/mdr.2019.03182020Adult, Anti-Bacterial Agents, Dental Clinics/*statistics & numerical data, Female, Genes, Bacterial, Genotype, Humans, Male, Methicillin-Resistant Staphylococcus aureus/*genetics, Microbial Sensitivity Tests, Middle Aged, Nose/microbiology, Staphylococcus/genetics/isolation & purification, United Arab Emirates/epidemiology, Young AdultPathogenicity
Phylogeny32102470Phenotypic and Molecular Detection of Biofilm Formation in Staphylococcus aureus Isolated from Different Sources in Algeria.Achek R, Hotzel H, Nabi I, Kechida S, Mami D, Didouh N, Tomaso H, Neubauer H, Ehricht R, Monecke S, El-Adawy HPathogens10.3390/pathogens90201532020
Pathogenicity33389264Antibiotic resistance profile and molecular characterization of Staphylococcus aureus strains isolated in hospitals in Kabul, Afghanistan.Naimi HM, Andre C, Bes M, Tristan A, Gustave CA, Vandenesch F, Nazari QA, Laurent F, Dupieux CEur J Clin Microbiol Infect Dis10.1007/s10096-020-04130-02021Afghanistan/epidemiology, Anti-Bacterial Agents/*pharmacology, *Drug Resistance, Bacterial, Humans, Staphylococcal Infections/*epidemiology/*microbiology, Staphylococcus aureus/*drug effects/genetics, Virulence Factors/genetics
35992657Diversity of clonal complex 22 methicillin-resistant Staphylococcus aureus isolates in Kuwait hospitals.Boswihi SS, Verghese T, Udo EEFront Microbiol10.3389/fmicb.2022.9709242022

Reference

@idauthorstitledoi/urlcatalogue
20215Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ10.1099/ijsem.0.004332
67301Curators of the DSMZhttps://www.dsmz.de/collection/catalogue/details/culture/DSM-111210Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 111210)
68375Automatically annotated from API ID32STA
112644Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.StrainInfo: A central database for resolving microbial strain identifiers10.60712/SI-ID405235.1