Strain identifier

BacDive ID: 1599

Type strain: Yes

Species: Bacteroides thetaiotaomicron

Strain Designation: E50 (VPI 5482), VPI-5482

Strain history: ATCC 29148 <-- E. P. Cato VPI 5482 <-- H. Werner E 50.

NCBI tax ID(s): 818 (species)

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General

@ref: 714

BacDive-ID: 1599

DSM-Number: 2079

keywords: genome sequence, 16S sequence, Bacteria, anaerobe, mesophilic

description: Bacteroides thetaiotaomicron E50 is an anaerobe, mesophilic bacterium that was isolated from human faeces.

NCBI tax id

  • NCBI tax id: 818
  • Matching level: species

strain history

@refhistory
714<- NCTC <- H. Werner, E50 (VPI 5482)
67770ATCC 29148 <-- E. P. Cato VPI 5482 <-- H. Werner E 50.

doi: 10.13145/bacdive1599.20230509.8.1

Name and taxonomic classification

LPSN

  • @ref: 20215
  • description: domain/bacteria
  • keyword: phylum/bacteroidota
  • domain: Bacteria
  • phylum: Bacteroidota
  • class: Bacteroidia
  • order: Bacteroidales
  • family: Bacteroidaceae
  • genus: Bacteroides
  • species: Bacteroides thetaiotaomicron
  • full scientific name: Bacteroides thetaiotaomicron (Distaso 1912) Castellani and Chalmers 1919 (Approved Lists 1980)

  • synonyms

    @refsynonym
    20215Bacteroides fragilis subsp. thetaiotaomicron
    20215Bacillus thetaiotaomicron

@ref: 714

domain: Bacteria

phylum: Bacteroidetes

class: Bacteroidia

order: Bacteroidales

family: Bacteroidaceae

genus: Bacteroides

species: Bacteroides thetaiotaomicron

full scientific name: Bacteroides thetaiotaomicron (Distaso 1912) Castellani and Chalmers 1919 emend. Hahnke et al. 2016

strain designation: E50 (VPI 5482), VPI-5482

type strain: yes

Morphology

cell morphology

@refmotilityconfidencegram stain
69480no91.919
6948099.998negative

colony morphology

  • @ref: 714
  • incubation period: 1-2 days

Culture and growth conditions

culture medium

@refnamegrowthlinkcomposition
714COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)yeshttps://mediadive.dsmz.de/medium/693Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base
714CHOPPED MEAT MEDIUM (DSMZ Medium 78)yeshttps://mediadive.dsmz.de/medium/78Name: CHOPPED MEAT MEDIUM (DSMZ Medium 78) Composition: Ground beef 500.0 g/l Casitone 30.0 g/l Agar 15.0 g/l Ethanol 9.5 g/l (optional) K2HPO4 5.0 g/l Yeast extract 5.0 g/l L-Cysteine HCl 0.5 g/l Haemin 0.005 g/l (optional) Resazurin 0.001 g/l Vitamin K3 0.0005 g/l (optional) Vitamin K1 (optional) NaOH (optional) Distilled water
41048MEDIUM 20 - for Anaerobic bacteriayesAgar (15.000 g);Glucose (5.000 g);Yeast extract (20.000 g);Tryptone (30.000 g);Cysteine hydrochloride (0.500 g);distilled water (1000.000 ml);Hemin solution -M00149 (25.000 ml)
42081MEDIUM 20 - for Anaerobic bacteriayesAgar (15.000 g);Glucose (5.000 g);Yeast extract (20.000 g);Tryptone (30.000 g);Cysteine hydrochloride (0.500 g);distilled water (1000.000 ml);Hemin solution -M00149 (25.000 ml)
714FASTIDIOUS ANAEROBE BROTH (DSMZ Medium 1203a)yeshttps://mediadive.dsmz.de/medium/1203aName: FASTIDIOUS ANAEROBE BROTH (DSMZ Medium 1203a) Composition: Fastidious Anaerobe Basal Broth 35.4 g/l Distilled water

culture temp

@refgrowthtypetemperaturerange
714positivegrowth37mesophilic
41048positivegrowth37mesophilic
42081positivegrowth37mesophilic
45331positivegrowth37mesophilic
67770positivegrowth37mesophilic

Physiology and metabolism

oxygen tolerance

@refoxygen toleranceconfidence
714anaerobe
45331anaerobe
69480anaerobe99.322

spore formation

@refspore formationconfidence
69481no100
69480no99.989

observation

  • @ref: 67770
  • observation: quinones: MK-10, MK-11

metabolite utilization

@refChebi-IDmetaboliteutilization activitykind of utilization tested
6836727082trehalose+builds acid from
6836762345L-rhamnose+builds acid from
6836716634raffinose+builds acid from
683676731melezitose+builds acid from
6836716024D-mannose+builds acid from
6836717057cellobiose+builds acid from
683674853esculin+hydrolysis
6836730849L-arabinose+builds acid from
6836765327D-xylose+builds acid from
6836717306maltose+builds acid from
6836717992sucrose+builds acid from
6836717716lactose+builds acid from
6836717634D-glucose+builds acid from
6836716199urea-hydrolysis
6836727897tryptophan+energy source
6838016199urea-hydrolysis
6838029016arginine-hydrolysis
6838016024D-mannose+fermentation
6838016634raffinose+fermentation
6838029985L-glutamate+degradation
6838017632nitrate-reduction
6838027897tryptophan+energy source

metabolite production

@refChebi-IDmetaboliteproduction
6836735581indoleyes
6838035581indoleyes

metabolite tests

@refChebi-IDmetaboliteindole test
6838035581indole+
6836735581indole+

enzymes

@refvalueactivityec
68380serine arylamidase-
68380glycin arylamidase-
68380alanine arylamidase+3.4.11.2
68380pyrrolidonyl arylamidase-3.4.19.3
68380leucine arylamidase+3.4.11.1
68380leucyl glycin arylamidase+3.4.11.1
68380proline-arylamidase-3.4.11.5
68380L-arginine arylamidase+
68380alkaline phosphatase+3.1.3.1
68380tryptophan deaminase+4.1.99.1
68380alpha-fucosidase+3.2.1.51
68380glutamate decarboxylase+4.1.1.15
68380N-acetyl-beta-glucosaminidase+3.2.1.52
68380beta-glucuronidase-3.2.1.31
68380alpha-arabinosidase+3.2.1.55
68380beta-glucosidase+3.2.1.21
68380alpha-glucosidase+3.2.1.20
68380beta-Galactosidase 6-phosphate-
68380beta-galactosidase+3.2.1.23
68380alpha-galactosidase+3.2.1.22
68380arginine dihydrolase-3.5.3.6
68380urease-3.5.1.5
68367beta-glucosidase+3.2.1.21
68367urease-3.5.1.5

API 20A

@refINDUREGLUMANLACSACMALSALXYLARAGELESCGLYCELMNEMLZRAFSORRHATRE
714+-+-+++-++-+-++++-++
714+-++++++++-++/-+++++/-++
714+-+-+++-++-+-++++-++
714+-+-+++-++++-++++-++

API rID32A

@refUREADH Argalpha GALbeta GALbeta GPalpha GLUbeta GLUalpha ARAbeta GURbeta NAGMNERAFGDCalpha FUCNITINDPALArgAProALGAPheALeuAPyrATyrAAlaAGlyAHisAGGASerA
714--++-+++-+++++-+++-++/-+--+-+/-+/--
714--++-+++-+++++-+++-++/-+--+-+/-+/--
714--++-+++-+++++-+++-++/-+--+-+/---
714--++-+++-+++++-+++-++/-+--+-+/-+/--
714--++-+++-+++++-+++-+-+--+-++-
714--++-+++-+++++-+++-+-+--+----
714--++-+++-+++++-+++-+-+--+----
714--++-+++-+++++-+++-+-+--+----
714--++-+++-+++++-+++-+-+--+--+-
714--++-+++-+++++-+++-++/-+-+/-+-++/--

Isolation, sampling and environmental information

isolation

@refsample type
714human faeces
45331Human feces
67770Human feces

isolation source categories

Cat1Cat2Cat3
#Host#Human
#Host Body Product#Gastrointestinal tract#Feces (Stool)

Safety information

risk assessment

  • @ref: 714
  • biosafety level: 2
  • biosafety level comment: Risk group (German classification)

Sequence information

16S sequences

@refdescriptionaccessionlengthdatabaseNCBI tax ID
20218Bacteroides thetaiotaomicron 16S-23S ribosomal RNA intergenic spacer region, partial sequenceAF172710523ena818
20218Bacteroides thetaiotaomicron strain DSM 2079 16S ribosomal RNA gene, partial sequenceHQ012026931ena818
20218Bacteroides thetaiotaomicron (ATCC 29148) 16S ribosomal RNAL164891475ena818
714Bacteroides thetaiotaomicron VPI-5482, complete genomeAE0159286260361ena226186
67770Bacteroides thetaiotaomicron gene for 16S ribosomal RNA, partial sequence, strain: JCM 5827AB5107101461ena818
67770Bacteroides thetaiotaomicron 16S ribosomal RNA gene, partial sequenceM587631482ena818

Genome sequences

@refdescriptionaccessionassembly leveldatabaseNCBI tax ID
66792Bacteroides thetaiotaomicron DSM 2079GCA_014131755completencbi818
66792Bacteroides thetaiotaomicron VPI-5482GCA_000011065completencbi226186
66792Bacteroides thetaiotaomicron VPI-5482GCA_002959695contigncbi818
66792Bacteroides thetaiotaomicron NCTC10582GCA_900445595contigncbi818
66792Bacteroides thetaiotaomicron VPI-5482GCA_020179495contigncbi818
66792Bacteroides thetaiotaomicron VPI-5482226186.70wgspatric226186
66792Bacteroides thetaiotaomicron VPI-5482226186.12completepatric226186
66792Bacteroides thetaiotaomicron VPI-5482226186.66plasmidpatric226186
66792Bacteroides thetaiotaomicron strain DSM 2079818.1357completepatric818
66792Bacteroides thetaiotaomicron strain FDAARGOS_912818.1393wgspatric818
66792Bacteroides thetaiotaomicron strain NCTC10582818.190wgspatric818
66792Bacteroides thetaiotaomicron VPI-5482637000026completeimg226186
66792Bacteroides thetaiotaomicron VPI 5482GCA_022453665completencbi818
66792Bacteroides thetaiotaomicron DSM 2079GCA_028539425contigncbi818

GC content

@refGC-contentmethod
71442.0thermal denaturation, midpoint method (Tm)
71442.9sequence analysis
6777042thermal denaturation, midpoint method (Tm)

Genome-based predictions

predictions

traitpredictionconfidencetraining_data
spore-formingno100no
motileno91.904no
flagellatedno96.945no
gram-positiveno97.103no
anaerobicyes94.443yes
aerobicno96.026yes
halophileno90.279no
spore-formingno94.57no
glucose-utilyes87.734no
thermophileno99.646yes
glucose-fermentyes71no

External links

@ref: 714

culture collection no.: DSM 2079, ATCC 29148, NCTC 10582, CCUG 10774, CIP 104206, VPI 5482, JCM 5827, CGMCC 1.5132

straininfo link

  • @ref: 71244
  • straininfo: 39378

literature

topicPubmed-IDtitleauthorsjournalDOIyearmeshtopic2
Metabolism2022195Metabolism of 1,4-dinitro-2-methylpyrrole, a mutagen formed by a sorbic acid-nitrite reaction, by intestinal bacteria.Shu YZ, Kingston DG, Van Tassell RL, Wilkins TDEnviron Mol Mutagen10.1002/em.28501703071991Bacteria, Anaerobic/*metabolism, Bacteroides/metabolism, Biotransformation, Chromatography, High Pressure Liquid, Chromatography, Thin Layer, Feces/microbiology, Female, Humans, Intestines/*microbiology, Kinetics, Magnetic Resonance Spectroscopy, Male, Mutagens/*metabolism, Oxidation-Reduction, Pyrroles/*metabolism/toxicity, Sodium Nitrite/*metabolism, Sorbic Acid/*metabolismPathogenicity
Phylogeny8833931[Use of cell-surface antigens of Bacteroides thetaiotaomicron in the passive hemagglutination test and in the inhibition of passive hemagglutination].Rokosz A, Meisel-Mikolajczyk FMed Dosw Mikrobiol1995Animals, Antigens, Surface/isolation & purification/*pharmacology, Bacteroides/classification/*immunology, Hemagglutination/*drug effects, Hemagglutination Tests, Humans, In Vitro Techniques, Intestines/microbiology, Lipopolysaccharides/isolation & purification/*pharmacology, Pancreatic Fistula/microbiology, Rabbits, Sheep, Species SpecificityPathogenicity
Metabolism11298652A heat labile soluble factor from Bacteroides thetaiotaomicron VPI-5482 specifically increases the galactosylation pattern of HT29-MTX cells.Freitas M, Cayuela C, Antoine JM, Piller F, Sapin C, Trugnan GCell Microbiol10.1046/j.1462-5822.2001.00113.x2001Bacteroides/*chemistry, Biological Factors/*chemistry/metabolism/*pharmacology, Blotting, Western, Cell Differentiation, Culture Media, Conditioned/chemistry/pharmacology, Dipeptidyl Peptidase 4/metabolism, Enzyme Activation/drug effects, Flow Cytometry, Galactose/metabolism, Galactosyltransferases/genetics/metabolism, Glycosylation/drug effects, HT29 Cells, Hot Temperature, Humans, Intestinal Mucosa/cytology/drug effects/enzymology/metabolism, Lectins/metabolism, Microscopy, Confocal, Microvilli/drug effects/enzymology/metabolism, Molecular Weight, RNA, Messenger/genetics/metabolism, Reverse Transcriptase Polymerase Chain Reaction, Solubility, Symbiosis, ThermodynamicsPathogenicity
Phylogeny15071033Identification of Bacteroides thetaiotaomicron on the basis of an unexpected specific amplicon of universal 16S ribosomal DNA PCR.Teng LJ, Hsueh PR, Huang YH, Tsai JCJ Clin Microbiol10.1128/JCM.42.4.1727-1730.20042004Bacterial Typing Techniques, Bacteroides/*classification/genetics/isolation & purification, Bacteroides Infections/microbiology, DNA Primers, DNA, Bacterial/analysis/genetics, DNA, Ribosomal/analysis/*genetics, Humans, Polymerase Chain Reaction/*methods, RNA, Ribosomal, 16S/*genetics, Sensitivity and Specificity, Species SpecificityPathogenicity
Genetics15805532Genetic and structural analysis of the Bacteroides conjugative transposon CTn341.Bacic M, Parker AC, Stagg J, Whitley HP, Wells WG, Jacob LA, Smith CJJ Bacteriol10.1128/JB.187.8.2858-2869.20052005Bacteroides/*genetics, *Conjugation, Genetic, DNA Transposable Elements/*genetics, DNA, Bacterial/metabolism, DNA, Circular/genetics, Gene Order, Genes, Bacterial, Genome, Bacterial, Molecular Sequence DataMetabolism
Enzymology15952775HAD superfamily phosphotransferase substrate diversification: structure and function analysis of HAD subclass IIB sugar phosphatase BT4131.Lu Z, Dunaway-Mariano D, Allen KNBiochemistry10.1021/bi050009j2005Amino Acid Sequence, Bacterial Proteins/chemistry/genetics/metabolism, Bacteroides/*enzymology, Base Sequence, Binding Sites, Cloning, Molecular, Crystallography, X-Ray, DNA Primers, Kinetics, Models, Molecular, Phosphoric Monoester Hydrolases/*chemistry/genetics/*metabolism, Protein Conformation, Recombinant Proteins/chemistry/metabolism, Substrate Specificity, Sulfates/metabolismMetabolism
Metabolism16552061Characterization of Bacteroides fragilis hemolysins and regulation and synergistic interactions of HlyA and HlyB.Robertson KP, Smith CJ, Gough AM, Rocha ERInfect Immun10.1128/IAI.74.4.2304-2316.20062006Animals, Bacterial Proteins/chemistry/genetics/*metabolism, Bacteroides fragilis/genetics/*metabolism, Base Sequence, Carrier Proteins/chemistry/genetics/*metabolism, Cattle, Culture Media, Escherichia coli/genetics, Escherichia coli Proteins/chemistry/genetics/*metabolism, Hemolysin Proteins/*chemistry/genetics/*metabolism, Hemolysis/physiology, Humans, Iron/metabolism, Membrane Glycoproteins/chemistry/genetics/metabolism, Mutation, Oxidative Stress/physiology, Perforin, Pore Forming Cytotoxic Proteins, *Protein Interaction Mapping, Rabbits, Sequence DeletionCultivation
16887504Carbohydrate utilization patterns and substrate preferences in Bacteroides thetaiotaomicron.Degnan BA, Macfarlane GTAnaerobe10.1016/s1075-9964(95)80392-01995
Metabolism17654545Crystal structures of two novel dye-decolorizing peroxidases reveal a beta-barrel fold with a conserved heme-binding motif.Zubieta C, Krishna SS, Kapoor M, Kozbial P, McMullan D, Axelrod HL, Miller MD, Abdubek P, Ambing E, Astakhova T, Carlton D, Chiu HJ, Clayton T, Deller MC, Duan L, Elsliger MA, Feuerhelm J, Grzechnik SK, Hale J, Hampton E, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kumar A, Marciano D, Morse AT, Nigoghossian E, Okach L, Oommachen S, Reyes R, Rife CL, Schimmel P, van den Bedem H, Weekes D, White A, Xu Q, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IAProteins10.1002/prot.215502007Amino Acid Motifs, Amino Acid Sequence, Bacterial Proteins/*chemistry/physiology, Bacteroides/enzymology, Catalytic Domain, Coloring Agents/*metabolism, *Conserved Sequence, Crystallography, X-Ray, Heme/*metabolism, Molecular Sequence Data, Multienzyme Complexes/*chemistry/physiology, Peroxidases/*chemistry/metabolism, Protein Binding, *Protein Folding, Protein Structure, Secondary, Shewanella/enzymologyEnzymology
Enzymology18398008The catalytic scaffold of the haloalkanoic acid dehalogenase enzyme superfamily acts as a mold for the trigonal bipyramidal transition state.Lu Z, Dunaway-Mariano D, Allen KNProc Natl Acad Sci U S A10.1073/pnas.07108001052008Bacterial Proteins/chemistry, Bacteroides/*enzymology, *Catalysis, Crystallography, X-Ray, Hydrolases/*chemistry, Phosphoric Monoester Hydrolases, Protein Conformation, Static Electricity
Pathogenicity19149766Use of a Bacteroides thetaiotaomicron-specific alpha-1-6, mannanase quantitative PCR to detect human faecal pollution in water.Yampara-Iquise H, Zheng G, Jones JE, Carson CAJ Appl Microbiol10.1111/j.1365-2672.2008.03895.x2008Animals, Bacteroides/genetics/*isolation & purification, *DNA Primers, DNA, Bacterial/genetics, Feces/*microbiology, Humans, Polymerase Chain Reaction/*methods, Sensitivity and Specificity, Sewage/microbiology, *Water Microbiology, *Water PollutionEnzymology
Phylogeny20008108Bacteroides faecis sp. nov., isolated from human faeces.Kim MS, Roh SW, Bae JWInt J Syst Evol Microbiol10.1099/ijs.0.020024-02009Adult, Bacteroides/*classification/genetics/*isolation & purification/metabolism, Base Composition, DNA, Bacterial/genetics, Fatty Acids/metabolism, Feces/*microbiology, Humans, Male, Molecular Sequence Data, Phylogeny, RNA, Ribosomal, 16S/geneticsMetabolism
Enzymology21989931The X-ray crystallographic structure and specificity profile of HAD superfamily phosphohydrolase BT1666: comparison of paralogous functions in B. thetaiotaomicron.Lu Z, Dunaway-Mariano D, Allen KNProteins10.1002/prot.231372011Bacteroides/*enzymology, Catalytic Domain, Crystallography, X-Ray, Kinetics, Models, Molecular, Phosphoric Monoester Hydrolases/*chemistry/metabolism, Protein Conformation, Substrate SpecificityMetabolism
Pathogenicity22140448A conformational switch in the active site of BT_2972, a methyltransferase from an antibiotic resistant pathogen B. thetaiotaomicron.Kumar V, Sivaraman JPLoS One10.1371/journal.pone.00275432011Amino Acid Sequence, Anti-Bacterial Agents/*pharmacology, Bacteroides/*drug effects/*enzymology, Calorimetry, *Catalytic Domain, Crystallography, X-Ray, Drug Resistance, Bacterial/*drug effects, Methyltransferases/*chemistry/*metabolism, Models, Molecular, Molecular Sequence Data, Protein Conformation, S-Adenosylhomocysteine/chemistry/metabolism, S-Adenosylmethionine/chemistry/metabolism, Sequence Analysis, Protein, Structural Homology, Protein, Structure-Activity Relationship, Substrate Specificity/drug effects, ThermodynamicsMetabolism
Phylogeny22544795Bacteroides reticulotermitis sp. nov., isolated from the gut of a subterranean termite (Reticulitermes speratus).Sakamoto M, Ohkuma MInt J Syst Evol Microbiol10.1099/ijs.0.040931-02012Animals, Bacterial Typing Techniques, Bacteroides/*classification/genetics/isolation & purification, Base Composition, DNA, Bacterial/genetics, Fatty Acids/analysis, Gastrointestinal Tract/*microbiology, Isoptera/*microbiology, Molecular Sequence Data, *Phylogeny, RNA, Ribosomal, 16S/genetics, Sequence Analysis, DNA, Vitamin K 2/analysisGenetics
Enzymology22776355Bacteroides thetaiotaomicron VPI-5482 glycoside hydrolase family 66 homolog catalyzes dextranolytic and cyclization reactions.Kim YM, Yamamoto E, Kang MS, Nakai H, Saburi W, Okuyama M, Mori H, Funane K, Momma M, Fujimoto Z, Kobayashi M, Kim D, Kimura AFEBS J10.1111/j.1742-4658.2012.08698.x2012Amino Acid Sequence, Bacteroides/*enzymology, Biocatalysis, Cloning, Molecular, Cyclization, Dextrans/*metabolism, Electrophoresis, Polyacrylamide Gel, Gene Expression, Glycoside Hydrolases/chemistry/genetics/*metabolism, Molecular Sequence Data, Phylogeny, Recombinant Proteins/metabolism, Sequence Homology, Amino AcidMetabolism
Metabolism23943617Discovery of beta-1,4-D-mannosyl-N-acetyl-D-glucosamine phosphorylase involved in the metabolism of N-glycans.Nihira T, Suzuki E, Kitaoka M, Nishimoto M, Ohtsubo K, Nakai HJ Biol Chem10.1074/jbc.M113.4690802013Acetylglucosamine/genetics/*metabolism, Adenosine Triphosphate/genetics/metabolism, Bacterial Proteins/genetics/*metabolism, Bacteroides/*enzymology/genetics, Biological Transport, Active/physiology, Glucans/genetics/*metabolism, Multigene Family/physiology, Phosphorylases/genetics/*metabolismEnzymology
Proteome24246060Filling out the structural map of the NTF2-like superfamily.Eberhardt RY, Chang Y, Bateman A, Murzin AG, Axelrod HL, Hwang WC, Aravind LBMC Bioinformatics10.1186/1471-2105-14-3272013Bacterial Proteins/*chemistry, Bacteroides/chemistry, Campylobacter jejuni/chemistry, Catalytic Domain, Crystallography, X-Ray, Ligands, Nucleocytoplasmic Transport Proteins/*chemistry, Peptide Mapping/*methods, Protein Folding, Protein Multimerization, Protein Structure, Tertiary, Ruminococcus/chemistry
Genetics24742328Structural genomics analysis of uncharacterized protein families overrepresented in human gut bacteria identifies a novel glycoside hydrolase.Sheydina A, Eberhardt RY, Rigden DJ, Chang Y, Li Z, Zmasek CC, Axelrod HL, Godzik ABMC Bioinformatics10.1186/1471-2105-15-1122014Amino Acid Sequence, Bacterial Proteins/*chemistry/genetics, Bacteroides/enzymology, Computational Biology, Gastrointestinal Tract/microbiology, Genomics, Glycoside Hydrolases/*chemistry/genetics, Humans, Protein Structure, TertiaryPathogenicity
25452698Evaluative profiling of arsenic sensing and regulatory systems in the human microbiome project genomes.Isokpehi RD, Udensi UK, Simmons SS, Hollman AL, Cain AE, Olofinsae SA, Hassan OA, Kashim ZA, Enejoh OA, Fasesan DE, Nashiru OMicrobiol Insights10.4137/MBI.S180762014
Metabolism25719195The gut bacterium Bacteroides thetaiotaomicron influences the virulence potential of the enterohemorrhagic Escherichia coli O103:H25.Iversen H, Lindback T, L'Abee-Lund TM, Roos N, Aspholm M, Stenfors Arnesen LPLoS One10.1371/journal.pone.01181402015Bacteroides/*metabolism, Enteropathogenic Escherichia coli/genetics/metabolism/*pathogenicity, *Gene Expression Regulation, Bacterial, HeLa Cells, Humans, *Microbial Consortia, Operon, Shiga Toxin 2/genetics/metabolism, Transcriptome, Virulence/geneticsPathogenicity
Biotechnology25988123Degradation of Fructans and Production of Propionic Acid by Bacteroides thetaiotaomicron are Enhanced by the Shortage of Amino Acids.Adamberg S, Tomson K, Vija H, Puurand M, Kabanova N, Visnapuu T, Jogi E, Alamae T, Adamberg KFront Nutr10.3389/fnut.2014.000212014Metabolism
Metabolism26370847The microbiota shifts the iron sensing of intestinal cells.Deschemin JC, Noordine ML, Remot A, Willemetz A, Afif C, Canonne-Hergaux F, Langella P, Karim Z, Vaulont S, Thomas M, Nicolas GFASEB J10.1096/fj.15-2768402015Animals, Cation Transport Proteins/genetics/*metabolism, Colon/metabolism/microbiology, Cytochromes b/genetics/metabolism, Duodenum/metabolism/microbiology, Ferritins/blood, Intestinal Mucosa/*metabolism/microbiology, Iron/*metabolism, Liver/metabolism, Male, Mice, Mice, Inbred C57BL, *Microbiota
Metabolism28397401Anaerobic utilization of Fe(III)-xenosiderophores among Bacteroides species and the distinct assimilation of Fe(III)-ferrichrome by Bacteroides fragilis within the genus.Rocha ER, Krykunivsky ASMicrobiologyopen10.1002/mbo3.4792017Anaerobiosis, Bacterial Proteins/genetics/metabolism, Bacteroides/genetics/*metabolism, Biological Transport, Enterobactin/analogs & derivatives/metabolism, Ferric Compounds/*metabolism, Ferrichrome/*metabolism, Gene Deletion, Genetic Complementation Test, Glucosides/metabolism, Membrane Transport Proteins/genetics/metabolism, Siderophores/*metabolism
Pathogenicity28404640Comprehensive evaluation of the bactericidal activities of free bile acids in the large intestine of humans and rodents.Watanabe M, Fukiya S, Yokota AJ Lipid Res10.1194/jlr.M0751432017Animals, Anti-Bacterial Agents/chemistry/metabolism/*pharmacology, Bacteroidaceae/cytology/*drug effects/physiology, Bifidobacterium breve/cytology/*drug effects/physiology, Bile Acids and Salts/chemistry/metabolism/*pharmacology, Cell Membrane/drug effects, Humans, Hydrogen-Ion Concentration, Hydrophobic and Hydrophilic Interactions, Intestine, Large/*metabolism, Intracellular Space/drug effects, Mice, Microbial Viability/drug effectsMetabolism
29430381Characterization of a glycoside hydrolase family 78 alpha-l-rhamnosidase from Bacteroides thetaiotaomicron VPI-5482 and identification of functional residues.Li B, Ji Y, Li Y, Ding G3 Biotech10.1007/s13205-018-1139-92018
Metabolism29535205The Biosynthesis of Lipooligosaccharide from Bacteroides thetaiotaomicron.Jacobson AN, Choudhury BP, Fischbach MAmBio10.1128/mBio.02289-172018Bacteroides thetaiotaomicron/*genetics/*metabolism, Biosynthetic Pathways/*genetics, Lipopolysaccharides/*biosynthesis/chemistry, Mutation, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Metabolism30243237Characterization of a alpha-l-rhamnosidase from Bacteroides thetaiotaomicron with high catalytic efficiency of epimedin C.Wu T, Pei J, Ge L, Wang Z, Ding G, Xiao W, Zhao LBioorg Chem10.1016/j.bioorg.2018.08.0042018Amino Acid Sequence, Bacteroides Infections/microbiology, Bacteroides thetaiotaomicron/chemistry/*enzymology, Flavonoids/*metabolism, Glycoside Hydrolases/chemistry/*metabolism, Glycosides/metabolism, Hesperidin/metabolism, Hydrolysis, Rutin/metabolism, Substrate SpecificityEnzymology
Pathogenicity30833358A Putative Type V Pilus Contributes to Bacteroides thetaiotaomicron Biofilm Formation Capacity.Mihajlovic J, Bechon N, Ivanova C, Chain F, Almeida A, Langella P, Beloin C, Ghigo JMJ Bacteriol10.1128/JB.00650-182019Animals, Bacterial Adhesion/physiology, Bacteroides thetaiotaomicron/*physiology, Biofilms/*growth & development, Fimbriae, Bacterial/*physiology, Gastrointestinal Microbiome/physiology, Humans, Male, Mice, Mice, Inbred C3H
Metabolism30936421Single cell fluorescence imaging of glycan uptake by intestinal bacteria.Hehemann JH, Reintjes G, Klassen L, Smith AD, Ndeh D, Arnosti C, Amann R, Abbott DWISME J10.1038/s41396-019-0406-z2019Bacteroides thetaiotaomicron/genetics/*metabolism, *Carbohydrate Metabolism, Cell Wall/chemistry, Dietary Carbohydrates/*metabolism, Fluorescence, *Gastrointestinal Microbiome, Genome, Bacterial/*genetics, Intestines/microbiology, Pectins/metabolism, Polysaccharides/*metabolismGenetics
Phylogeny31635446Bifidobacterium adolescentis P2P3, a Human Gut Bacterium Having Strong Non-Gelatinized Resistant Starch-Degrading Activity.Jung DH, Kim GY, Kim IY, Seo DH, Nam YD, Kang H, Song Y, Park CSJ Microbiol Biotechnol10.4014/jmb.1909.090102019Adult, Animals, Bifidobacterium adolescentis/classification/genetics/isolation & purification/*metabolism, Coculture Techniques, Cytokines, Feces/microbiology, Gastrointestinal Microbiome/*physiology, Gelatin, Humans, Immunologic Factors, Macrophages/drug effects/metabolism, Male, Mice, Mice, Inbred BALB C, Phylogeny, Prebiotics/microbiology, Probiotics/pharmacology, Starch/*metabolismMetabolism
31690674Intestinal IgA Regulates Expression of a Fructan Polysaccharide Utilization Locus in Colonizing Gut Commensal Bacteroides thetaiotaomicron.Joglekar P, Ding H, Canales-Herrerias P, Pasricha PJ, Sonnenburg JL, Peterson DAmBio10.1128/mBio.02324-192019Animals, Bacteroides thetaiotaomicron/*immunology, Diet/methods, Dietary Carbohydrates/*immunology, Fructans/*immunology, Gastrointestinal Microbiome/*immunology, Germ-Free Life/immunology, Immunoglobulin A/*immunology, Intestines/*immunology/*microbiology, Mice, Mice, Inbred C57BL
Pathogenicity32019793Endotoxin Producers Overgrowing in Human Gut Microbiota as the Causative Agents for Nonalcoholic Fatty Liver Disease.Fei N, Bruneau A, Zhang X, Wang R, Wang J, Rabot S, Gerard P, Zhao LmBio10.1128/mBio.03263-192020Adult, Animals, Child, Preschool, Diet, High-Fat, Endotoxins/*biosynthesis, Enterobacteriaceae/genetics/*metabolism, Female, *Gastrointestinal Microbiome, Germ-Free Life, Humans, Male, Mice, Mice, Inbred C57BL, Non-alcoholic Fatty Liver Disease/*microbiology, Obesity, Morbid, *Signal Transduction, Toll-Like Receptor 4/*metabolismMetabolism
32576670Capsular Polysaccharide Cross-Regulation Modulates Bacteroides thetaiotaomicron Biofilm Formation.Bechon N, Mihajlovic J, Vendrell-Fernandez S, Chain F, Langella P, Beloin C, Ghigo JMmBio10.1128/mBio.00729-202020Animals, Bacterial Adhesion/genetics, Bacterial Capsules/chemistry/*genetics, Bacteroides thetaiotaomicron/*genetics/*physiology, Biofilms/*growth & development, Gene Expression Regulation, Bacterial, Male, Mice, Mice, Inbred C3H, Mutagenesis, Polysaccharides, Bacterial/*chemistry, Specific Pathogen-Free Organisms
Biotechnology33936013GABA Production by Human Intestinal Bacteroides spp.: Prevalence, Regulation, and Role in Acid Stress Tolerance.Otaru N, Ye K, Mujezinovic D, Berchtold L, Constancias F, Cornejo FA, Krzystek A, de Wouters T, Braegger C, Lacroix C, Pugin BFront Microbiol10.3389/fmicb.2021.6568952021Stress
Metabolism34074097Rational Design for Broadened Substrate Specificity and Enhanced Activity of a Novel Acetyl Xylan Esterase from Bacteroides thetaiotaomicron.Wang L, Han X, Wang Y, Wei X, Liu S, Shao S, Yang S, Sun L, Xin FJ Agric Food Chem10.1021/acs.jafc.1c007502021Acetylesterase/genetics/metabolism, *Bacteroides thetaiotaomicron/genetics, Molecular Docking Simulation, Substrate Specificity
Metabolism35080445Lipidomics Analysis of Outer Membrane Vesicles and Elucidation of the Inositol Phosphoceramide Biosynthetic Pathway in Bacteroides thetaiotaomicron.Sartorio MG, Valguarnera E, Hsu FF, Feldman MFMicrobiol Spectr10.1128/spectrum.00634-212022Bacterial Outer Membrane/chemistry/metabolism, Bacterial Proteins/genetics/metabolism, Bacteroides thetaiotaomicron/genetics/*metabolism, Biosynthetic Pathways, Ceramides/*biosynthesis/chemistry, Glycerophospholipids/chemistry/metabolism, Inositol/*metabolism, Lipidomics, Mass Spectrometry, Operon, Sphingolipids/chemistry/metabolism, Transport Vesicles/chemistry/genetics/*metabolism
Metabolism35145026Bacteroides thetaiotaomicron uses a widespread extracellular DNase to promote bile-dependent biofilm formation.Bechon N, Mihajlovic J, Lopes AA, Vendrell-Fernandez S, Deschamps J, Briandet R, Sismeiro O, Martin-Verstraete I, Dupuy B, Ghigo JMProc Natl Acad Sci U S A10.1073/pnas.21112281192022Bacterial Proteins/genetics/*metabolism, Bacteroides thetaiotaomicron/*enzymology/genetics/physiology, Bile/*metabolism, Biofilms/*growth & development, DNA, Bacterial/genetics/metabolism, Deoxyribonucleases/genetics/*metabolism, Gene Expression Regulation, Bacterial/*physiology, Gene Expression Regulation, Enzymologic/physiologyEnzymology
Metabolism35462273Modification to increase the thermostability and catalytic efficiency of alpha-L-rhamnosidase from Bacteroides thetaiotaomicron and high-level expression.Lu C, Dong Y, Ke K, Zou K, Wang Z, Xiao W, Pei J, Zhao LEnzyme Microb Technol10.1016/j.enzmictec.2022.1100402022*Bacteroides thetaiotaomicron/genetics, Glycoside Hydrolases/metabolism, Glycosides, Hydrogen-Ion Concentration, Rhamnose
Pathogenicity36113733Growth of succinate consumer Dialister hominis is supported by Bacteroides thetaiotaomicron.Sakamoto M, Ikeyama N, Iino T, Ohkuma MAnaerobe10.1016/j.anaerobe.2022.1026422022Humans, *Bacteroides thetaiotaomicron, Succinic Acid, *Gastrointestinal Microbiome, Succinates

Reference

@idauthorscataloguedoi/urltitlejournalpubmed
714Curators of the DSMZLeibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 2079)https://www.dsmz.de/collection/catalogue/details/culture/DSM-2079
20215Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.10.1099/ijsem.0.004332List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ
20218Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.10.1016/j.syapm.2013.11.002StrainInfo introduces electronic passports for microorganisms.Syst Appl Microbiol. 37: 42-50 201424321274
41048Curators of the CIPhttps://brclims.pasteur.fr/brcWeb/souche/detail/1/16088
42081Curators of the CIPhttps://brclims.pasteur.fr/brcWeb/souche/detail/1/16091
45331Curators of the CCUGCulture Collection University of Gothenburg (CCUG) (CCUG 10774)https://www.ccug.se/strain?id=10774
66792Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmannhttps://diaspora-project.de/progress.html#genomesAutomatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)
67770Curators of the JCMhttps://jcm.brc.riken.jp/en/
68367Automatically annotated from API 20A
68380Automatically annotated from API rID32A
69480Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmannhttps://diaspora-project.de/progress.html#genomesPredictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)
69481Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch10.21203/rs.3.rs-2527258/v1Predictions based on the model GenomeNet Sporulation v. 1
71244Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.10.60712/SI-ID39378.1StrainInfo: A central database for resolving microbial strain identifiers