Strain identifier
BacDive ID: 15462
Type strain: 
Species: Streptomyces peucetius
Strain Designation: 106FI
Strain history: C. C. Ho H3502 <-- IMRU 3920 <-- Farmitalia FI 106.
NCBI tax ID(s): 316280 (strain), 1950 (species)
version 8.1 (current version)
General
@ref: 10124
BacDive-ID: 15462
DSM-Number: 41231
keywords: genome sequence, 16S sequence, Bacteria, spore-forming, mesophilic, antibiotic compound production
description: Streptomyces peucetius 106FI is a spore-forming, mesophilic bacterium that produces antibiotic compounds.
NCBI tax id
| NCBI tax id | Matching level |
|---|---|
| 316280 | strain |
| 1950 | species |
strain history
| @ref | history |
|---|---|
| 10124 | <- R. E. Gordon, IMRU <- B. Camerino, Farmitalia, Fi 106, ("Streptomyces peuceticus ssp. caesius") |
| 67770 | C. C. Ho H3502 <-- IMRU 3920 <-- Farmitalia FI 106. |
doi: 10.13145/bacdive15462.20230509.8.1
Name and taxonomic classification
LPSN
- @ref: 20215
- description: domain/bacteria
- keyword: phylum/actinomycetota
- domain: Bacteria
- phylum: Actinomycetota
- class: Actinomycetes
- order: Kitasatosporales
- family: Streptomycetaceae
- genus: Streptomyces
- species: Streptomyces peucetius
- full scientific name: Streptomyces peucetius Grein et al. 1963 (Approved Lists 1980)
@ref: 10124
domain: Bacteria
phylum: Actinobacteria
class: Actinobacteria
order: Actinomycetales
family: Streptomycetaceae
genus: Streptomyces
species: Streptomyces peucetius
full scientific name: Streptomyces peucetius Grein et al. 1963
strain designation: 106FI
type strain: no
Morphology
cell morphology
| @ref | motility | confidence | gram stain |
|---|---|---|---|
| 69480 | no | 91.202 | |
| 69480 | 100 | positive |
multimedia
- @ref: 10124
- multimedia content: https://www.dsmz.de/microorganisms/photos/DSM_41231.jpg
- caption: Medium 65 28°C
- intellectual property rights: © Leibniz-Institut DSMZ
Culture and growth conditions
culture medium
| @ref | name | growth | link | composition |
|---|---|---|---|---|
| 10124 | STARCH - MINERAL SALT - AGAR (STMS) (DSMZ Medium 252) | yes | https://mediadive.dsmz.de/medium/252 | Name: STARCH - MINERAL SALT - AGAR (STMS) (DSMZ Medium 252) Composition: Agar 14.985 g/l Starch 9.99001 g/l (NH4)2SO4 1.998 g/l CaCO3 1.998 g/l K2HPO4 0.999001 g/l MgSO4 x 7 H2O 0.999001 g/l NaCl 0.999001 g/l FeSO4 x 7 H2O 0.000999001 g/l MnCl2 x 4 H2O 0.000999001 g/l ZnSO4 x 7 H2O 0.000999001 g/l Distilled water |
| 10124 | GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) | yes | https://mediadive.dsmz.de/medium/65 | Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 18.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water |
culture temp
| @ref | growth | type | temperature | range |
|---|---|---|---|---|
| 10124 | positive | growth | 28 | mesophilic |
| 67770 | positive | growth | 28 | mesophilic |
Physiology and metabolism
spore formation
| @ref | spore formation | confidence |
|---|---|---|
| 69481 | yes | 100 |
| 69480 | yes | 100 |
compound production
- @ref: 10124
- compound: adriamycin
metabolite production
| @ref | Chebi-ID | metabolite | production |
|---|---|---|---|
| 67770 | 41977 | daunorubicin | yes |
| 67770 | 28748 | doxorubicin | yes |
Safety information
risk assessment
- @ref: 10124
- biosafety level: 1
- biosafety level comment: Risk group (German classification)
Sequence information
16S sequences
| @ref | description | accession | length | database | NCBI tax ID |
|---|---|---|---|---|---|
| 20218 | Streptomyces peucetius subsp. caesius gene for 16S rRNA, partial sequence, strain: NBRC 14660 | AB184608 | 1479 | ena | 55158 |
| 20218 | Streptomyces peucetius subsp. caesius strain CHEM8003UV1-3G3 16S ribosomal RNA gene, partial sequence | KC137355 | 1426 | ena | 55158 |
Genome sequences
| @ref | description | accession | assembly level | database | NCBI tax ID |
|---|---|---|---|---|---|
| 66792 | Streptomyces peucetius subsp. caesius ATCC 27952 | GCA_002777535 | complete | ncbi | 316280 |
| 66792 | Streptomyces peucetius subsp. caesius ATCC 27952 | 316280.3 | complete | patric | 316280 |
| 66792 | Streptomyces peucetius ATCC 27952 | 2867039408 | complete | img | 316280 |
Genome-based predictions
predictions
| trait | prediction | confidence | training_data |
|---|---|---|---|
| spore-forming | yes | 100 | no |
| flagellated | no | 98.011 | no |
| gram-positive | yes | 88.48 | no |
| anaerobic | no | 98.645 | no |
| aerobic | yes | 89.287 | no |
| halophile | no | 92.821 | no |
| spore-forming | yes | 94.647 | no |
| glucose-util | yes | 90.826 | no |
| thermophile | no | 97.701 | no |
| motile | no | 94.194 | no |
| glucose-ferment | no | 90.411 | no |
External links
@ref: 10124
culture collection no.: DSM 41231, ATCC 27952, IFO 14660, IMRU 3920, IPV 1946, NBRC 14660, JCM 10035, ATCC 43817, CECT 3227, NRRL B-16117
straininfo link
- @ref: 84550
- straininfo: 70701
literature
| topic | Pubmed-ID | title | authors | journal | DOI | year | mesh | topic2 |
|---|---|---|---|---|---|---|---|---|
| Metabolism | 1729206 | Regulation of secondary metabolism in Streptomyces spp. and overproduction of daunorubicin in Streptomyces peucetius. | Stutzman-Engwall KJ, Otten SL, Hutchinson CR | J Bacteriol | 10.1128/jb.174.1.144-154.1992 | 1992 | Amino Acid Sequence, Anthracyclines, Antibiotics, Antineoplastic/analysis/*biosynthesis, Base Sequence, Daunorubicin/analysis/*biosynthesis, Drug Resistance, Microbial, Gene Expression, Molecular Sequence Data, Mutagenesis, Insertional, Protein Conformation, Restriction Mapping, Sequence Homology, Nucleic Acid, Streptomyces/genetics/*metabolism, Transformation, Genetic | Genetics |
| Enzymology | 2345153 | Cloning and expression of daunorubicin biosynthesis genes from Streptomyces peucetius and S. peucetius subsp. caesius. | Otten SL, Stutzman-Engwall KJ, Hutchinson CR | J Bacteriol | 10.1128/jb.172.6.3427-3434.1990 | 1990 | Anthracyclines, Antibiotics, Antineoplastic/biosynthesis, *Cloning, Molecular, Daunorubicin/*biosynthesis, *Gene Expression, *Genes, Bacterial, Genetic Complementation Test, Mutation, Streptomyces/*genetics/metabolism | Metabolism |
| Pathogenicity | 7492117 | Expression of Streptomyces peucetius genes for doxorubicin resistance and aklavinone 11-hydroxylase in Streptomyces galilaeus ATCC 31133 and production of a hybrid aclacinomycin. | Hwang CK, Kim HS, Hong YS, Kim YH, Hong SK, Kim SJ, Lee JJ | Antimicrob Agents Chemother | 10.1128/AAC.39.7.1616 | 1995 | Aclarubicin/*analogs & derivatives/biosynthesis, Aryl Hydrocarbon Hydroxylases/genetics, Carbohydrate Sequence, Doxorubicin/*pharmacology, Drug Resistance, Microbial, Gene Expression, *Genes, Bacterial, Humans, Molecular Sequence Data, Neoplasms/drug therapy, Streptomyces/enzymology/*genetics/*metabolism, Tumor Cells, Cultured/drug effects | Genetics |
| Enzymology | 7961477 | Molecular cloning and characterization of the aklavinone 11-hydroxylase gene of Streptomyces peucetius subsp. caesius ATCC 27952. | Hong YS, Hwang CK, Hong SK, Kim YH, Lee JJ | J Bacteriol | 10.1128/jb.176.22.7096-7101.1994 | 1994 | Amino Acid Sequence, Aryl Hydrocarbon Hydroxylases/*genetics, Base Sequence, Cloning, Molecular, Flavin-Adenine Dinucleotide, Genes, Fungal/*genetics, Molecular Sequence Data, NAD, Naphthacenes/metabolism, Sequence Analysis, DNA, Streptomyces/enzymology/*genetics, Transcription, Genetic | Genetics |
| Pathogenicity | 11692678 | [Characteristics of mutants of Streptomyces peucetius subsp. caesius ATCC 27952 resistant to anthracycline antibiotics]. | Dubyts'ka LP, Fedorenko VO | Mikrobiol Z | 2001 | Antibiotics, Antineoplastic/biosynthesis/*pharmacology, Culture Media, Daunorubicin/biosynthesis/pharmacology, Doxorubicin/biosynthesis/pharmacology, Drug Resistance, Microbial/*genetics, Methylnitronitrosoguanidine/pharmacology, Mutagenesis/drug effects, Mutation, Spores, Bacterial/drug effects, Streptomyces/drug effects/*genetics/metabolism | Cultivation | |
| Metabolism | 12422641 | [Effect of glucose on the antibiotic activity and antibiotic resistance of Streptomyces peucetius subsp. caesius ATCC 27952-2 and its mutants]. | Dubitskaia LP, Fedorenko VA | Antibiot Khimioter | 2002 | Antibiotics, Antineoplastic/*metabolism/*pharmacology, Biomass, Culture Media, Depression, Chemical, Glucose/metabolism/*pharmacology, Mutation, Streptomyces/*drug effects/genetics/growth & development/metabolism | Pathogenicity | |
| Phylogeny | 15111132 | Genome analyses of Streptomyces peucetius ATCC 27952 for the identification and comparison of cytochrome P450 complement with other Streptomyces. | Parajuli N, Basnet DB, Chan Lee H, Sohng JK, Liou K | Arch Biochem Biophys | 10.1016/j.abb.2004.03.011 | 2004 | Amino Acid Sequence, Cytochrome P-450 Enzyme System/*chemistry/classification/*genetics/metabolism, Gene Expression Profiling/*methods, *Genome, Bacterial, Molecular Sequence Data, Phylogeny, Sequence Alignment, *Sequence Analysis, Protein, Sequence Homology, Amino Acid, Streptomyces/chemistry/classification/*enzymology/*genetics | Genetics |
| Enzymology | 15921897 | Identification and characterization of the afsR homologue regulatory gene from Streptomyces peucetius ATCC 27952. | Parajuli N, Viet HT, Ishida K, Tong HT, Lee HC, Liou K, Sohng JK | Res Microbiol | 10.1016/j.resmic.2005.03.005 | 2005 | Amino Acid Sequence, Anthraquinones/analysis, Bacterial Proteins/genetics, Clavulanic Acid/analysis, Cloning, Molecular, DNA, Bacterial/chemistry/genetics, DNA-Binding Proteins/*genetics, Doxorubicin/analysis, Gene Expression, Gene Expression Regulation, Bacterial, Genes, Bacterial, *Genes, Regulator, Lactones/analysis, Methyltransferases/genetics, Molecular Sequence Data, Promoter Regions, Genetic, Sequence Analysis, DNA, Sequence Homology, Amino Acid, Streptomyces/*genetics, Streptomycin/analysis, Transcription Factors/*genetics | Genetics |
| Metabolism | 18421418 | Heterologous expression of metK1-sp and afsR-sp in Streptomyces venezuelae for the production of pikromycin. | Maharjan S, Oh TJ, Lee HC, Sohng JK | Biotechnol Lett | 10.1007/s10529-008-9735-0 | 2008 | Chromatography, High Pressure Liquid, Gene Expression Regulation, Bacterial, *Genes, Bacterial, Macrolides/analysis/chemistry/*metabolism, Plasmids/metabolism, Reverse Transcriptase Polymerase Chain Reaction, Streptomyces/*genetics/growth & development | Biotechnology |
| Enzymology | 18612244 | Identification of a cryptic type III polyketide synthase (1,3,6,8-tetrahydroxynaphthalene synthase) from Streptomyces peucetius ATCC 27952. | Ghimire GP, Oh TJ, Liou K, Sohng JK | Mol Cells | 117 | 2008 | Acyltransferases/chemistry/*isolation & purification, Amino Acid Sequence, Chromatography, High Pressure Liquid, Electrophoresis, Polyacrylamide Gel, Molecular Sequence Data, Naphthols/chemistry, Naphthoquinones/chemistry, Phenotype, Sequence Alignment, Sequence Analysis, Protein, Spectrometry, Mass, Electrospray Ionization, Streptomyces/*enzymology | Genetics |
| Enzymology | 18667848 | Cloning and functional characterization of the germacradienol synthase (spterp13) from Streptomyces peucetius ATCC 27952. | Ghimire GP, Oh TJ, Lee HC, Kim BG, Sohng JK | J Microbiol Biotechnol | 7474 | 2008 | Amino Acid Sequence, Bacterial Proteins/*chemistry/*genetics/isolation & purification/metabolism, *Cloning, Molecular, Escherichia coli/genetics/metabolism, Gene Expression, Molecular Sequence Data, Molecular Weight, Naphthols/*metabolism, Phylogeny, Recombinant Proteins/chemistry/genetics/isolation & purification/metabolism, Sequence Alignment, Streptomyces/chemistry/classification/*enzymology/genetics | Phylogeny |
| Metabolism | 19557446 | Exploration of geosmin synthase from Streptomyces peucetius ATCC 27952 by deletion of doxorubicin biosynthetic gene cluster. | Singh B, Oh TJ, Sohng JK | J Ind Microbiol Biotechnol | 10.1007/s10295-009-0605-0 | 2009 | Bacterial Proteins/genetics/*metabolism, Cloning, Molecular, Doxorubicin/*biosynthesis, Gene Dosage, Ligases/genetics/*metabolism, Metabolic Networks and Pathways/genetics, *Multigene Family, Naphthols/*metabolism, *Sequence Deletion, Sequence Homology, Amino Acid, Streptomyces/*enzymology/genetics | Enzymology |
| Metabolism | 19619853 | Enhancement of doxorubicin production by expression of structural sugar biosynthesis and glycosyltransferase genes in Streptomyces peucetius. | Malla S, Niraula NP, Liou K, Sohng JK | J Biosci Bioeng | 10.1016/j.jbiosc.2009.03.002 | 2009 | Bacterial Proteins/*biosynthesis/genetics, Cytochrome P-450 Enzyme System, Deoxy Sugars/genetics/*metabolism, Doxorubicin/*biosynthesis, Gene Expression, Glycosyltransferases/*biosynthesis/genetics, Methyltransferases/genetics, Plasmids/genetics/metabolism, Promoter Regions, Genetic/genetics, Streptomyces/*enzymology/genetics | Genetics |
| Metabolism | 19651502 | Self-resistance mechanism in Streptomyces peucetius: overexpression of drrA, drrB and drrC for doxorubicin enhancement. | Malla S, Niraula NP, Liou K, Sohng JK | Microbiol Res | 10.1016/j.micres.2009.04.002 | 2009 | ATP-Binding Cassette Transporters/genetics/*metabolism, Antibiotics, Antineoplastic/*biosynthesis/metabolism, Bacterial Proteins/genetics/*metabolism, DNA-Binding Proteins/genetics/*metabolism, Doxorubicin/*biosynthesis/metabolism, Drug Resistance, Bacterial/genetics, Multidrug Resistance-Associated Proteins, Streptomyces/genetics/*metabolism | |
| Metabolism | 19767465 | Improved squalene production via modulation of the methylerythritol 4-phosphate pathway and heterologous expression of genes from Streptomyces peucetius ATCC 27952 in Escherichia coli. | Ghimire GP, Lee HC, Sohng JK | Appl Environ Microbiol | 10.1128/AEM.01402-09 | 2009 | Alkyl and Aryl Transferases/genetics/metabolism, Bacterial Proteins/genetics/metabolism, *Biotechnology, Carbon-Carbon Double Bond Isomerases/genetics/metabolism, Escherichia coli/enzymology/*genetics/metabolism, Escherichia coli Proteins/genetics/metabolism, Farnesyl-Diphosphate Farnesyltransferase/genetics/metabolism, *Gene Expression Regulation, Bacterial, Geranylgeranyl-Diphosphate Geranylgeranyltransferase, Geranyltranstransferase/genetics/metabolism, Hemiterpenes, Molecular Sequence Data, Squalene/chemistry/isolation & purification/*metabolism, Streptomyces/*genetics, Transferases/genetics/metabolism | Biotechnology |
| Metabolism | 19777229 | Precursor for biosynthesis of sugar moiety of doxorubicin depends on rhamnose biosynthetic pathway in Streptomyces peucetius ATCC 27952. | Singh B, Lee CB, Sohng JK | Appl Microbiol Biotechnol | 10.1007/s00253-009-2225-z | 2009 | Amino Acid Sequence, Bacterial Proteins/genetics/metabolism, Base Sequence, Biosynthetic Pathways/genetics, Cloning, Molecular, DNA, Bacterial/genetics/metabolism, Doxorubicin/*biosynthesis/metabolism, Enzyme Assays, Escherichia coli/genetics/metabolism, Frameshift Mutation, Gene Silencing, Genes, Bacterial, Genetic Complementation Test, Glucose/*analogs & derivatives/metabolism, Hexosamines/biosynthesis, Hydro-Lyases/*genetics/*metabolism, Molecular Sequence Data, Multigene Family, Rhamnose/*biosynthesis/metabolism, Streptomyces/enzymology/genetics/*metabolism, Thymine Nucleotides/*metabolism, Transformation, Bacterial | Enzymology |
| Pathogenicity | 20045726 | Improvement in doxorubicin productivity by overexpression of regulatory genes in Streptomyces peucetius. | Malla S, Niraula NP, Liou K, Sohng JK | Res Microbiol | 10.1016/j.resmic.2009.12.003 | 2010 | Biosynthetic Pathways/genetics, Doxorubicin/*biosynthesis, *Gene Dosage, Gene Expression Profiling, *Gene Expression Regulation, Bacterial, Genetic Engineering, Humans, Molecular Structure, *Plasmids, Recombination, Genetic, Streptomyces/*genetics/*metabolism | Metabolism |
| Metabolism | 20116225 | Limitations in doxorubicin production from Streptomyces peucetius. | Malla S, Niraula NP, Singh B, Liou K, Sohng JK | Microbiol Res | 10.1016/j.micres.2009.11.006 | 2010 | Anthracyclines/metabolism, Biosynthetic Pathways, Cytochrome P-450 Enzyme Inhibitors, Doxorubicin/antagonists & inhibitors/*biosynthesis, Feedback, Physiological, Glycosylation, Hexosamines/biosynthesis, Streptomyces/*metabolism | Biotechnology |
| Genetics | 20163498 | Identification of the duplicated genes for S-adenosyl-l-methionine synthetase (metK1-sp and metK2-sp) in Streptomyces peucetius var. caesius ATCC 27952. | Oh TJ, Niraula NP, Liou K, Sohng JK | J Appl Microbiol | 10.1111/j.1365-2672.2010.04688.x | 2010 | Amino Acid Sequence, Doxorubicin/biosynthesis, *Genes, Duplicate, Methionine Adenosyltransferase/chemistry/*genetics/metabolism, Molecular Sequence Annotation, Molecular Sequence Data, Sequence Homology, Amino Acid, Streptomyces/*enzymology/genetics/growth & development | Metabolism |
| Biotechnology | 20508927 | Biotechnological doxorubicin production: pathway and regulation engineering of strains for enhanced production. | Niraula NP, Kim SH, Sohng JK, Kim ES | Appl Microbiol Biotechnol | 10.1007/s00253-010-2675-3 | 2010 | Antibiotics, Antineoplastic/*biosynthesis, Doxorubicin/*biosynthesis, Gene Expression Regulation, Bacterial, *Genetic Engineering, *Industrial Microbiology, Streptomyces/*genetics/*metabolism | Metabolism |
| Enzymology | 20888207 | Superoxide dismutase (SOD) genes in Streptomyces peucetius: effects of SODs on secondary metabolites production. | Kanth BK, Jnawali HN, Niraula NP, Sohng JK | Microbiol Res | 10.1016/j.micres.2010.07.003 | 2010 | Anti-Bacterial Agents/biosynthesis, Biomass, Cloning, Molecular, DNA, Bacterial/chemistry/genetics, Gene Expression, Gene Expression Profiling, *Metabolome, Molecular Sequence Data, Sequence Analysis, DNA, Streptomyces/*enzymology/genetics/*metabolism, Superoxide Dismutase/*genetics/*metabolism | Genetics |
| Metabolism | 20889382 | Homology modeling, binding site identification and docking in flavone hydroxylase CYP105P2 in Streptomyces peucetius ATCC 27952. | Kanth BK, Liou K, Sohng JK | Comput Biol Chem | 10.1016/j.compbiolchem.2010.08.002 | 2010 | Amino Acid Sequence, Binding Sites, Cytochrome P-450 Enzyme System/*chemistry/*metabolism, Flavones/*metabolism, Molecular Dynamics Simulation, Molecular Sequence Data, Protein Binding, Sequence Alignment, Sequence Homology, Amino Acid, Streptomyces/chemistry/*enzymology, Structural Homology, Protein | Genetics |
| Enzymology | 21193825 | Identification and characterization of a pantothenate kinase (PanK-sp) from streptomyces peucetius ATCC 27952. | Mandakh A, Niraula NP, Kim EP, Sohng JK | J Microbiol Biotechnol | JMB020-12-12 | 2010 | Anthraquinones/metabolism, Chromatography, Affinity, Cloning, Molecular, Coenzymes/metabolism, DNA, Bacterial/chemistry/genetics, Escherichia coli/genetics, Gene Expression, Molecular Sequence Data, Molecular Weight, NAD/metabolism, Phosphotransferases (Alcohol Group Acceptor)/chemistry/*isolation & purification/*metabolism, Recombinant Proteins/genetics/isolation & purification/metabolism, Sequence Analysis, DNA, Sequence Homology, Amino Acid, Streptomyces/*enzymology | Metabolism |
| Metabolism | 21308395 | Proteomic approach to enhance doxorubicin production in panK-integrated Streptomyces peucetius ATCC 27952. | Song E, Malla S, Yang YH, Lee K, Kim EJ, Lee HC, Sohng JK, Oh MK, Kim BG | J Ind Microbiol Biotechnol | 10.1007/s10295-010-0903-6 | 2011 | Anthracyclines/metabolism, Antibiotics, Antineoplastic/*biosynthesis, Daunorubicin/biosynthesis, Doxorubicin/*biosynthesis, Escherichia coli/genetics, Escherichia coli Proteins/genetics/metabolism, Glycosyltransferases/genetics/metabolism, Phosphotransferases (Alcohol Group Acceptor)/*genetics/metabolism, Proteomics, Streptomyces/enzymology/genetics/*metabolism | Biotechnology |
| Metabolism | 22112829 | Hydrogen peroxide-mediated dealkylation of 7-ethoxycoumarin by cytochrome P450 (CYP107AJ1) from Streptomyces peucetius ATCC27952. | Niraula NP, Kanth BK, Sohng JK, Oh TJ | Enzyme Microb Technol | 10.1016/j.enzmictec.2010.10.001 | 2010 | Amino Acid Sequence, Biotechnology/*methods, Coumarins/*metabolism, Cytochrome P-450 Enzyme System/*chemistry/genetics/*metabolism, Dealkylation/drug effects, Escherichia coli/enzymology/genetics, Hydrogen Peroxide/*pharmacology, Models, Molecular, Molecular Sequence Data, Recombinant Proteins/chemistry/genetics/metabolism, Sequence Alignment, Sequence Homology, Amino Acid, Streptomyces/*enzymology/genetics/metabolism, Structural Homology, Protein | Enzymology |
| Genetics | 22825833 | Genome-based cryptic gene discovery and functional identification of NRPS siderophore peptide in Streptomyces peucetius. | Park HM, Kim BG, Chang D, Malla S, Joo HS, Kim EJ, Park SJ, Sohng JK, Kim PI | Appl Microbiol Biotechnol | 10.1007/s00253-012-4268-9 | 2012 | Computational Biology, DNA, Bacterial/chemistry/genetics, *Genetic Association Studies, Genome, Bacterial, Genomics, Mass Spectrometry, Molecular Weight, Multigene Family, Peptide Synthases/*genetics/*metabolism, Peptides, Cyclic/chemistry/genetics/metabolism, Sequence Analysis, DNA, Siderophores/chemistry/*genetics/*metabolism, Streptomyces/*genetics/*metabolism | Metabolism |
| Genetics | 22893224 | Exploration of two epimerase homologs in Streptomyces peucetius ATCC 27952. | Singh B, Oh TJ, Sohng JK | Appl Microbiol Biotechnol | 10.1007/s00253-012-4327-2 | 2012 | Amino Acid Sequence, Carbohydrate Epimerases/*genetics/*metabolism, Gene Deletion, Gene Order, Genetic Complementation Test, Microscopy, Molecular Sequence Data, Sequence Alignment, Sequence Homology, Amino Acid, Streptomyces/cytology/*enzymology/*genetics/growth & development | Metabolism |
| Metabolism | 24786531 | Switching antibiotics production on and off in actinomycetes by an IclR family transcriptional regulator from Streptomyces peucetius ATCC 27952. | Chaudhary AK, Singh B, Maharjan S, Jha AK, Kim BG, Sohng JK | J Microbiol Biotechnol | 10.4014/jmb.1403.03026 | 2014 | Actinobacteria/*genetics/*metabolism, Anti-Bacterial Agents/*biosynthesis, *Gene Expression Regulation, Bacterial, Pigments, Biological/biosynthesis, Recombinant Proteins/genetics/metabolism, Transcription Factors/*genetics/*metabolism | Biotechnology |
| Metabolism | 24858680 | Methylation and subsequent glycosylation of 7,8-dihydroxyflavone. | Koirala N, Pandey RP, Parajuli P, Jung HJ, Sohng JK | J Biotechnol | 10.1016/j.jbiotec.2014.05.005 | 2014 | Escherichia coli/genetics/metabolism, Flavones/*metabolism, Flavonoids/*metabolism, Glycosylation, *Metabolic Engineering, Methylation, Protein O-Methyltransferase/biosynthesis/genetics/*metabolism, Streptomyces/enzymology | Enzymology |
| Enzymology | 25022520 | Characterization of dephosphocoenzyme A kinase from Streptomyces peucetius ATCC27952, and its application for doxorubicin overproduction. | Lee NR, Rimal H, Lee JH, Oh TJ | J Microbiol Biotechnol | 10.4014/jmb.1404.04053 | 2014 | Biotechnology, Doxorubicin/analysis/*metabolism, Escherichia coli/genetics, Metabolic Networks and Pathways, Phosphotransferases (Alcohol Group Acceptor)/*chemistry/genetics/isolation & purification/*metabolism, Plasmids, Recombinant Fusion Proteins/*chemistry/genetics/isolation & purification/*metabolism, Streptomyces/enzymology/*genetics | Biotechnology |
| Metabolism | 25406531 | Activation of Cryptic hop Genes from Streptomyces peucetius ATCC 27952 Involved in Hopanoid Biosynthesis. | Ghimire GP, Koirala N, Sohng JK | J Microbiol Biotechnol | 10.4014/jmb.1408.08058 | 2015 | Cloning, Molecular, Genes, Bacterial/*genetics, Multigene Family/*genetics, Recombinant Proteins/genetics/metabolism, Streptomyces/*genetics/metabolism, Triterpenes/*metabolism | Enzymology |
| Metabolism | 26085470 | Structure determination of a siderophore peucechelin from Streptomyces peucetius. | Kodani S, Komaki H, Suzuki M, Kobayakawa F, Hemmi H | Biometals | 10.1007/s10534-015-9866-4 | 2015 | Gallium/chemistry, Hydroxamic Acids/*chemistry, Iron/chemistry/*metabolism, Macromolecular Substances/chemistry, Magnetic Resonance Spectroscopy, Peptides, Cyclic/*chemistry, *Protein Conformation, Siderophores/*chemistry/genetics, Streptomyces/chemistry/genetics | |
| Enzymology | 26334717 | Understanding of real alternative redox partner of Streptomyces peucetius DoxA: Prediction and validation using in silico and in vitro analyses. | Rimal H, Lee SW, Lee JH, Oh TJ | Arch Biochem Biophys | 10.1016/j.abb.2015.08.019 | 2015 | Bacterial Proteins/*chemistry/genetics, Catalytic Domain, Cytochrome P-450 Enzyme System/*chemistry/genetics, Daunorubicin/*chemistry, Doxorubicin/*chemistry, Escherichia coli/genetics/metabolism, Ferredoxins/*chemistry, Gene Expression, Hydrogen-Ion Concentration, Hydroxylation, Kinetics, Molecular Docking Simulation, NADH, NADPH Oxidoreductases/*chemistry/genetics, Oxidation-Reduction, Protein Structure, Secondary, Protein Structure, Tertiary, Pseudomonas putida/chemistry/enzymology, Recombinant Proteins/chemistry/genetics, Streptomyces/*chemistry/enzymology, Structural Homology, Protein, Substrate Specificity, Temperature | Metabolism |
| Metabolism | 27231902 | Crystal Structure of Cytochrome P450 (CYP105P2) from Streptomyces peucetius and Its Conformational Changes in Response to Substrate Binding. | Lee CW, Lee JH, Rimal H, Park H, Lee JH, Oh TJ | Int J Mol Sci | 10.3390/ijms17060813 | 2016 | Bacterial Proteins/*chemistry/metabolism, Catalytic Domain, Crystallography, X-Ray, Cytochrome P-450 Enzyme System/*chemistry/metabolism, Hydrogen Bonding, Hydrophobic and Hydrophilic Interactions, Ligands, Models, Molecular, Protein Binding, Protein Structure, Secondary, Streptomyces/chemistry/*enzymology | Enzymology |
| Biotechnology | 27664727 | Overexpression of a pathway specific negative regulator enhances production of daunorubicin in bldA deficient Streptomyces peucetius ATCC 27952. | Pokhrel AR, Chaudhary AK, Nguyen HT, Dhakal D, Le TT, Shrestha A, Liou K, Sohng JK | Microbiol Res | 10.1016/j.micres.2016.06.009 | 2016 | Anti-Bacterial Agents/*biosynthesis, Bacterial Proteins/*genetics, Chromatography, High Pressure Liquid, Codon, Cytochrome P-450 Enzyme System/*deficiency, Daunorubicin/*biosynthesis/chemistry, *Gene Expression, *Metabolic Networks and Pathways, Streptomyces/*genetics/*metabolism, Transcription, Genetic | Metabolism |
| Metabolism | 29043664 | Substrate Scope of O-Methyltransferase from Streptomyces peucetius for Biosynthesis of Diverse Natural Products Methoxides. | Parajuli P, Pandey RP, Nguyen THT, Dhakal D, Sohng JK | Appl Biochem Biotechnol | 10.1007/s12010-017-2603-4 | 2017 | *Bacterial Proteins/genetics/metabolism, *Escherichia coli/genetics/metabolism, Flavonoids/genetics/*metabolism, *Methyltransferases/genetics/metabolism, Recombinant Proteins/genetics/metabolism, Streptomyces/enzymology/*genetics | Enzymology |
| Genetics | 29307836 | Complete genome sequence of Streptomyces peucetius ATCC 27952, the producer of anticancer anthracyclines and diverse secondary metabolites. | Dhakal D, Lim SK, Kim DH, Kim BG, Yamaguchi T, Sohng JK | J Biotechnol | 10.1016/j.jbiotec.2017.12.024 | 2018 | Anthracyclines/*metabolism/therapeutic use, Daunorubicin/biosynthesis/chemistry, Doxorubicin/biosynthesis/chemistry, Genome, Bacterial/*genetics, Humans, Molecular Sequence Annotation, Polyketide Synthases/biosynthesis/chemistry, Secondary Metabolism/genetics, Streptomyces/chemistry/*genetics/metabolism, *Whole Genome Sequencing | Metabolism |
| Metabolism | 29602983 | Genome-guided exploration of metabolic features of Streptomyces peucetius ATCC 27952: past, current, and prospect. | Thuan NH, Dhakal D, Pokhrel AR, Chu LL, Van Pham TT, Shrestha A, Sohng JK | Appl Microbiol Biotechnol | 10.1007/s00253-018-8957-x | 2018 | Antibiotics, Antineoplastic/metabolism, Biotechnology/*trends, Daunorubicin/metabolism, Doxorubicin/metabolism, Genome, Bacterial/*genetics, Streptomyces/enzymology/*genetics/*metabolism | Genetics |
| Genetics | 30031480 | Implication of orphan histidine kinase (OhkAsp) in biosynthesis of doxorubicin and daunorubicin in Streptomyces peucetius ATCC 27952. | Pokhrel AR, Nguyen HT, Dhakal D, Chaudhary AK, Sohng JK | Microbiol Res | 10.1016/j.micres.2018.05.007 | 2018 | Antibiotics, Antineoplastic/*biosynthesis, DNA Mutational Analysis, Daunorubicin/*biosynthesis, Doxorubicin/*biosynthesis, Gene Deletion, Gene Expression Regulation, Bacterial, Genotype, Histidine Kinase/genetics/*metabolism, Phenotype, Streptomyces/cytology/*enzymology/*metabolism | Metabolism |
| Enzymology | 32423668 | Biochemical characterization of a novel thermostable DFA I-forming inulin fructotransferases from Streptomyces peucetius subsp. caesius ATCC 27952. | Cheng M, Zhu Y, Chen Z, Guang C, Zhang W, Mu W | Enzyme Microb Technol | 10.1016/j.enzmictec.2020.109519 | 2020 | Biocatalysis, Biotransformation, Cloning, Molecular, Enzyme Stability, Genes, Bacterial, Hexosyltransferases/*genetics/*metabolism, Hydrogen-Ion Concentration, Mutagenesis, Site-Directed, Streptomyces/*enzymology/genetics, Sweetening Agents/*metabolism, *Temperature | Metabolism |
| Enzymology | 32958729 | Characterization of CYP125A13, the First Steroid C-27 Monooxygenase from Streptomyces peucetius ATCC27952. | Rimal H, Subedi P, Kim KH, Park H, Lee JH, Oh TJ | J Microbiol Biotechnol | 10.4014/jmb.2007.07004 | 2020 | Catalytic Domain, Cloning, Molecular, Cytochrome P-450 Enzyme System/metabolism, Ferredoxins/metabolism, Hydroxylation, Kinetics, Models, Chemical, Molecular Docking Simulation, NADH, NADPH Oxidoreductases, Oxidation-Reduction, Phylogeny, Pseudomonas putida/metabolism, Sequence Alignment, Steroid Hydroxylases/*chemistry/classification/genetics/*metabolism, Sterols/chemistry, Streptomyces/*enzymology/genetics/*metabolism, Substrate Specificity | Metabolism |
| Enzymology | 36411834 | Functional expression and purification of DoxA, a key cytochrome P450 from Streptomyces peucetius ATCC 27952. | Yang L, Yang D, Wang Q, Li J, Li HL, Pan L | PeerJ | 10.7717/peerj.14373 | 2022 |
Reference
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| 10124 | Curators of the DSMZ | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 41231) | https://www.dsmz.de/collection/catalogue/details/culture/DSM-41231 | |||
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| 20218 | Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P. | 10.1016/j.syapm.2013.11.002 | StrainInfo introduces electronic passports for microorganisms. | Syst Appl Microbiol. 37: 42-50 2014 | 24321274 | |
| 66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | https://diaspora-project.de/progress.html#genomes | Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | |||
| 66794 | Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg | 10.1093/nar/gkaa1025 | BRENDA, the ELIXIR core data resource in 2021: new developments and updates | Nucleic Acids Res. 49: D498-D508 2020 | 33211880 | |
| 67770 | Curators of the JCM | https://jcm.brc.riken.jp/en/ | ||||
| 69480 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | https://diaspora-project.de/progress.html#genomes | Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | |||
| 69481 | Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch | 10.21203/rs.3.rs-2527258/v1 | Predictions based on the model GenomeNet Sporulation v. 1 | |||
| 84550 | Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J. | 10.60712/SI-ID70701.1 | StrainInfo: A central database for resolving microbial strain identifiers |