Strain identifier
version 9.3 (current version)
General
@ref: 53871
BacDive-ID: 149461
keywords: genome sequence, Bacteria, anaerobe, spore-forming, mesophilic
description: Clostridioides difficile CCUG 37785 is an anaerobe, spore-forming, mesophilic bacterium of the family Peptostreptococcaceae.
NCBI tax id
- NCBI tax id: 1496
- Matching level: species
doi: 10.13145/bacdive149461.20250331.9.3
Name and taxonomic classification
LPSN
- @ref: 20215
- description: domain/bacteria
- keyword: phylum/bacillota
- domain: Bacteria
- phylum: Bacillota
- class: Clostridia
- order: Eubacteriales
- family: Peptostreptococcaceae
- genus: Clostridioides
- species: Clostridioides difficile
- full scientific name: Clostridioides difficile (Hall and O'Toole 1935) Lawson et al. 2016
synonyms
@ref synonym 20215 Peptoclostridium difficile 20215 Bacillus difficilis 20215 Clostridium difficile
@ref: 53871
domain: Bacteria
phylum: Firmicutes
class: Clostridia
order: Eubacteriales
family: Peptostreptococcaceae
genus: Clostridioides
species: Clostridioides difficile
type strain: no
Culture and growth conditions
culture temp
- @ref: 53871
- growth: positive
- type: growth
- temperature: 37
Physiology and metabolism
oxygen tolerance
| @ref | oxygen tolerance | confidence |
|---|---|---|
| 53871 | anaerobe | |
| 125438 | anaerobe | 91.819 |
| 125439 | anaerobe | 99.9 |
Sequence information
Genome sequences
| @ref | description | accession | assembly level | database | NCBI tax ID |
|---|---|---|---|---|---|
| 66792 | Clostridioides difficile CCUG37785 | GCA_019067085 | scaffold | ncbi | 1496 |
| 66792 | Clostridioides difficile strain CCUG37785 | 1496.6057 | wgs | patric | 1496 |
Genome-based predictions
predictions
| @ref | model | trait | description | prediction | confidence | training_data |
|---|---|---|---|---|---|---|
| 125438 | gram-positive | gram-positive | Positive reaction to Gram-staining | yes | 59.539 | no |
| 125438 | anaerobic | anaerobic | Ability to grow under anoxygenic conditions (including facultative anaerobes) | yes | 91.819 | yes |
| 125438 | aerobic | aerobic | Ability to grow under oxygenic conditions (including facultative aerobes) | no | 97.269 | no |
| 125438 | spore-forming | spore-forming | Ability to form endo- or exospores | yes | 66.777 | no |
| 125438 | thermophile | thermophilic | Ability to grow at temperatures above or equal to 45°C | no | 90.894 | no |
| 125438 | motile2+ | flagellated | Ability to perform flagellated movement | yes | 75.146 | no |
| 125439 | BacteriaNet | spore_formation | Ability to form endo- or exospores | yes | 55.5 | |
| 125439 | BacteriaNet | motility | Ability to perform movement | yes | 64.6 | |
| 125439 | BacteriaNet | gram_stain | Reaction to gram-staining | positive | 81.5 | |
| 125439 | BacteriaNet | oxygen_tolerance | Oxygenic conditions needed for growth | anaerobe | 99.9 |
External links
@ref: 53871
culture collection no.: CCUG 37785, ATCC 43601
literature
| topic | Pubmed-ID | title | authors | journal | DOI | year | mesh | topic2 |
|---|---|---|---|---|---|---|---|---|
| Pathogenicity | 35315695 | Genomic and Phenotypic Characterization of the Nontoxigenic Clostridioides difficile Strain CCUG37785 and Demonstration of Its Therapeutic Potential for the Prevention of C. difficile Infection. | Wang S, Heuler J, Wickramage I, Sun X | Microbiol Spectr | 10.1128/spectrum.01788-21 | 2022 | Animals, Bacterial Proteins/genetics, *Bacterial Toxins/genetics, Clostridioides, *Clostridioides difficile/genetics, *Clostridium Infections/prevention & control, Enterotoxins/genetics, Genomics, Mice | Genetics |
| 35583336 | Development of an Effective Nontoxigenic Clostridioides difficile-Based Oral Vaccine against C. difficile Infection. | Wang S, Zhu D, Sun X | Microbiol Spectr | 10.1128/spectrum.00263-22 | 2022 |
Reference
| @id | authors | title | doi/url | catalogue |
|---|---|---|---|---|
| 20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M. | List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ | 10.1099/ijsem.0.004332 | |
| 53871 | Curators of the CCUG | https://www.ccug.se/strain?id=37785 | Culture Collection University of Gothenburg (CCUG) (CCUG 37785) | |
| 66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | https://diaspora-project.de/progress.html#genomes | |
| 125438 | Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann | Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets | 10.1101/2024.08.12.607695 | |
| 125439 | Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy | deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 | https://github.com/GenomeNet/deepG |