Strain identifier

BacDive ID: 149461

Type strain: No

Species: Clostridioides difficile

NCBI tax ID(s): 1496 (species)

For citation purpose refer to the digital object identifier (doi) of the current version.
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General

@ref: 53871

BacDive-ID: 149461

keywords: genome sequence, Bacteria, anaerobe, spore-forming, mesophilic, Gram-positive

description: Clostridioides difficile CCUG 37785 is an anaerobe, spore-forming, mesophilic bacterium of the family Peptostreptococcaceae.

NCBI tax id

  • NCBI tax id: 1496
  • Matching level: species

doi: 10.13145/bacdive149461.20230509.8.1

Name and taxonomic classification

LPSN

  • @ref: 20215
  • description: domain/bacteria
  • keyword: phylum/bacillota
  • domain: Bacteria
  • phylum: Bacillota
  • class: Clostridia
  • order: Eubacteriales
  • family: Peptostreptococcaceae
  • genus: Clostridioides
  • species: Clostridioides difficile
  • full scientific name: Clostridioides difficile (Hall and O'Toole 1935) Lawson et al. 2016
  • synonyms

    @refsynonym
    20215Bacillus difficilis
    20215Peptoclostridium difficile
    20215Clostridium difficile

@ref: 53871

domain: Bacteria

phylum: Firmicutes

class: Clostridia

order: Eubacteriales

family: Peptostreptococcaceae

genus: Clostridioides

species: Clostridioides difficile

type strain: no

Morphology

cell morphology

  • @ref: 69480
  • gram stain: positive
  • confidence: 100

Culture and growth conditions

culture temp

  • @ref: 53871
  • growth: positive
  • type: growth
  • temperature: 37
  • range: mesophilic

Physiology and metabolism

oxygen tolerance

@refoxygen toleranceconfidence
53871anaerobe
69480anaerobe99.55

spore formation

@refspore formationconfidence
69480yes99.563
69481yes100

Sequence information

Genome sequences

@refdescriptionaccessionassembly leveldatabaseNCBI tax ID
66792Clostridioides difficile CCUG37785GCA_019067085scaffoldncbi1496
66792Clostridioides difficile strain CCUG377851496.6057wgspatric1496

Genome-based predictions

predictions

traitpredictionconfidencetraining_data
spore-formingyes100no
flagellatedno69.167no
gram-positiveyes91.51no
anaerobicyes98.691yes
aerobicno97.437no
halophileno92.972no
spore-formingyes93.72no
motileyes75.27no
thermophileno92.306yes
glucose-utilyes88.245no
glucose-fermentyes57.867no

External links

@ref: 53871

culture collection no.: CCUG 37785, ATCC 43601

literature

topicPubmed-IDtitleauthorsjournalDOIyearmeshtopic2
Pathogenicity35315695Genomic and Phenotypic Characterization of the Nontoxigenic Clostridioides difficile Strain CCUG37785 and Demonstration of Its Therapeutic Potential for the Prevention of C. difficile Infection.Wang S, Heuler J, Wickramage I, Sun XMicrobiol Spectr10.1128/spectrum.01788-212022Animals, Bacterial Proteins/genetics, *Bacterial Toxins/genetics, Clostridioides, *Clostridioides difficile/genetics, *Clostridium Infections/prevention & control, Enterotoxins/genetics, Genomics, MiceGenetics
35583336Development of an Effective Nontoxigenic Clostridioides difficile-Based Oral Vaccine against C. difficile Infection.Wang S, Zhu D, Sun XMicrobiol Spectr10.1128/spectrum.00263-222022

Reference

@idauthorstitledoi/urlcatalogue
20215Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ10.1099/ijsem.0.004332
53871Curators of the CCUGhttps://www.ccug.se/strain?id=37785Culture Collection University of Gothenburg (CCUG) (CCUG 37785)
66792Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg OvermannAutomatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)https://diaspora-project.de/progress.html#genomes
69480Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg OvermannPredictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)https://diaspora-project.de/progress.html#genomes
69481Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. MünchPredictions based on the model GenomeNet Sporulation v. 110.21203/rs.3.rs-2527258/v1